CN107158154A - 一种治疗风湿病的回药外用制剂及其制备方法 - Google Patents
一种治疗风湿病的回药外用制剂及其制备方法 Download PDFInfo
- Publication number
- CN107158154A CN107158154A CN201710457897.4A CN201710457897A CN107158154A CN 107158154 A CN107158154 A CN 107158154A CN 201710457897 A CN201710457897 A CN 201710457897A CN 107158154 A CN107158154 A CN 107158154A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- root
- external preparation
- blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 42
- 239000003814 drug Substances 0.000 title claims description 46
- 240000007551 Boswellia serrata Species 0.000 claims abstract description 16
- 241000112528 Ligusticum striatum Species 0.000 claims abstract description 16
- 235000013871 bee wax Nutrition 0.000 claims abstract description 16
- 239000012166 beeswax Substances 0.000 claims abstract description 16
- 235000003717 Boswellia sacra Nutrition 0.000 claims abstract description 15
- 235000012035 Boswellia serrata Nutrition 0.000 claims abstract description 15
- 239000004863 Frankincense Substances 0.000 claims abstract description 15
- 210000000582 semen Anatomy 0.000 claims abstract description 15
- 241000227129 Aconitum Species 0.000 claims abstract description 14
- 244000020518 Carthamus tinctorius Species 0.000 claims abstract description 14
- 241000723346 Cinnamomum camphora Species 0.000 claims abstract description 14
- 240000007311 Commiphora myrrha Species 0.000 claims abstract description 14
- 235000006965 Commiphora myrrha Nutrition 0.000 claims abstract description 14
- 235000007265 Myrrhis odorata Nutrition 0.000 claims abstract description 14
- 235000004072 Ocimum sanctum Nutrition 0.000 claims abstract description 14
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims abstract description 13
- 244000037364 Cinnamomum aromaticum Species 0.000 claims abstract description 13
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims abstract description 13
- 241000405414 Rehmannia Species 0.000 claims abstract description 13
- 229960000846 camphor Drugs 0.000 claims abstract description 13
- 229930008380 camphor Natural products 0.000 claims abstract description 13
- 235000018597 common camellia Nutrition 0.000 claims abstract description 13
- 239000011505 plaster Substances 0.000 claims abstract description 13
- RSWGJHLUYNHPMX-UHFFFAOYSA-N Abietic-Saeure Natural products C12CCC(C(C)C)=CC2=CCC2C1(C)CCCC2(C)C(O)=O RSWGJHLUYNHPMX-UHFFFAOYSA-N 0.000 claims abstract description 12
- 240000001548 Camellia japonica Species 0.000 claims abstract description 12
- KHPCPRHQVVSZAH-HUOMCSJISA-N Rosin Natural products O(C/C=C/c1ccccc1)[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 KHPCPRHQVVSZAH-HUOMCSJISA-N 0.000 claims abstract description 12
- KHPCPRHQVVSZAH-UHFFFAOYSA-N trans-cinnamyl beta-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OCC=CC1=CC=CC=C1 KHPCPRHQVVSZAH-UHFFFAOYSA-N 0.000 claims abstract description 12
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 claims abstract description 11
- 235000006226 Areca catechu Nutrition 0.000 claims abstract description 11
- 244000080767 Areca catechu Species 0.000 claims abstract description 10
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 244000136948 Ocimum sanctum Species 0.000 claims abstract 5
- 239000000203 mixture Substances 0.000 claims description 24
- 244000061520 Angelica archangelica Species 0.000 claims description 13
- 235000002566 Capsicum Nutrition 0.000 claims description 13
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims description 13
- 235000001287 Guettarda speciosa Nutrition 0.000 claims description 13
- 239000009636 Huang Qi Substances 0.000 claims description 13
- 235000006484 Paeonia officinalis Nutrition 0.000 claims description 13
- 239000006002 Pepper Substances 0.000 claims description 13
- 241000132171 Phryma leptostachya Species 0.000 claims description 13
- 235000016761 Piper aduncum Nutrition 0.000 claims description 13
- 240000003889 Piper guineense Species 0.000 claims description 13
- 235000017804 Piper guineense Nutrition 0.000 claims description 13
- 235000008184 Piper nigrum Nutrition 0.000 claims description 13
- 239000000843 powder Substances 0.000 claims description 13
- 241000756943 Codonopsis Species 0.000 claims description 12
- 244000246386 Mentha pulegium Species 0.000 claims description 12
- 235000016257 Mentha pulegium Nutrition 0.000 claims description 12
- 235000004357 Mentha x piperita Nutrition 0.000 claims description 12
- 235000001050 hortel pimenta Nutrition 0.000 claims description 12
- 239000000341 volatile oil Substances 0.000 claims description 12
- 239000000758 substrate Substances 0.000 claims description 11
- 238000010438 heat treatment Methods 0.000 claims description 8
- 238000000605 extraction Methods 0.000 claims description 7
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- 235000008331 Pinus X rigitaeda Nutrition 0.000 claims description 3
- 235000011613 Pinus brutia Nutrition 0.000 claims description 3
- 241000018646 Pinus brutia Species 0.000 claims description 3
- -1 asafoetide Substances 0.000 claims description 2
- 238000004891 communication Methods 0.000 claims description 2
- 229910052742 iron Inorganic materials 0.000 claims description 2
- 244000170916 Paeonia officinalis Species 0.000 claims 4
- 239000000463 material Substances 0.000 claims 2
- 230000036407 pain Effects 0.000 abstract description 50
- 208000002193 Pain Diseases 0.000 abstract description 49
- 239000008280 blood Substances 0.000 abstract description 46
- 210000004369 blood Anatomy 0.000 abstract description 45
- 230000000694 effects Effects 0.000 abstract description 24
- 230000001737 promoting effect Effects 0.000 abstract description 18
- 206010062717 Increased upper airway secretion Diseases 0.000 abstract description 14
- 208000026435 phlegm Diseases 0.000 abstract description 14
- 230000017531 blood circulation Effects 0.000 abstract description 13
- 230000008961 swelling Effects 0.000 abstract description 10
- 230000008901 benefit Effects 0.000 abstract description 6
- 230000001717 pathogenic effect Effects 0.000 abstract description 5
- 238000005728 strengthening Methods 0.000 abstract description 5
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 abstract description 3
- 230000001105 regulatory effect Effects 0.000 abstract description 3
- 210000002435 tendon Anatomy 0.000 abstract description 3
- 238000010792 warming Methods 0.000 abstract description 3
- 241000382455 Angelica sinensis Species 0.000 abstract 1
- 241000045403 Astragalus propinquus Species 0.000 abstract 1
- 208000017667 Chronic Disease Diseases 0.000 abstract 1
- 241000007126 Codonopsis pilosula Species 0.000 abstract 1
- 206010010356 Congenital anomaly Diseases 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 244000018716 Impatiens biflora Species 0.000 abstract 1
- 235000015912 Impatiens biflora Nutrition 0.000 abstract 1
- 235000006679 Mentha X verticillata Nutrition 0.000 abstract 1
- 235000002899 Mentha suaveolens Nutrition 0.000 abstract 1
- 235000001636 Mentha x rotundifolia Nutrition 0.000 abstract 1
- 208000004880 Polyuria Diseases 0.000 abstract 1
- 235000005155 Tanacetum balsamita Nutrition 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 230000035619 diuresis Effects 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 241000411851 herbal medicine Species 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 230000003571 opsonizing effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 description 17
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 17
- 229940079593 drug Drugs 0.000 description 15
- 208000006820 Arthralgia Diseases 0.000 description 13
- 235000009508 confectionery Nutrition 0.000 description 11
- 240000002837 Ocimum tenuiflorum Species 0.000 description 9
- 241000736199 Paeonia Species 0.000 description 9
- 210000004185 liver Anatomy 0.000 description 9
- 206010019233 Headaches Diseases 0.000 description 8
- 231100000869 headache Toxicity 0.000 description 8
- 208000034783 hypoesthesia Diseases 0.000 description 8
- 230000007812 deficiency Effects 0.000 description 7
- 210000003414 extremity Anatomy 0.000 description 7
- 208000014674 injury Diseases 0.000 description 7
- 210000001503 joint Anatomy 0.000 description 7
- 231100000862 numbness Toxicity 0.000 description 7
- 210000001124 body fluid Anatomy 0.000 description 6
- 239000010839 body fluid Substances 0.000 description 6
- 210000000038 chest Anatomy 0.000 description 6
- 230000001276 controlling effect Effects 0.000 description 6
- 208000002173 dizziness Diseases 0.000 description 6
- 238000000227 grinding Methods 0.000 description 6
- 210000004072 lung Anatomy 0.000 description 6
- 210000000952 spleen Anatomy 0.000 description 6
- 230000008736 traumatic injury Effects 0.000 description 6
- 206010011224 Cough Diseases 0.000 description 5
- 210000004247 hand Anatomy 0.000 description 5
- 210000003734 kidney Anatomy 0.000 description 5
- 231100000614 poison Toxicity 0.000 description 5
- 208000004371 toothache Diseases 0.000 description 5
- 206010012735 Diarrhoea Diseases 0.000 description 4
- 208000004044 Hypesthesia Diseases 0.000 description 4
- 206010030113 Oedema Diseases 0.000 description 4
- 210000001015 abdomen Anatomy 0.000 description 4
- 210000000988 bone and bone Anatomy 0.000 description 4
- 239000000796 flavoring agent Substances 0.000 description 4
- 235000019634 flavors Nutrition 0.000 description 4
- 235000013305 food Nutrition 0.000 description 4
- 230000001114 myogenic effect Effects 0.000 description 4
- 201000003068 rheumatic fever Diseases 0.000 description 4
- 210000002784 stomach Anatomy 0.000 description 4
- 239000003440 toxic substance Substances 0.000 description 4
- 231100000397 ulcer Toxicity 0.000 description 4
- 206010007247 Carbuncle Diseases 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 208000025865 Ulcer Diseases 0.000 description 3
- 206010046788 Uterine haemorrhage Diseases 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 230000000202 analgesic effect Effects 0.000 description 3
- 230000002146 bilateral effect Effects 0.000 description 3
- 210000004556 brain Anatomy 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 230000008602 contraction Effects 0.000 description 3
- 238000005469 granulation Methods 0.000 description 3
- 230000003179 granulation Effects 0.000 description 3
- 210000003127 knee Anatomy 0.000 description 3
- 230000033001 locomotion Effects 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 239000011347 resin Substances 0.000 description 3
- 229920005989 resin Polymers 0.000 description 3
- 206010039073 rheumatoid arthritis Diseases 0.000 description 3
- CCEKAJIANROZEO-UHFFFAOYSA-N sulfluramid Chemical group CCNS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F CCEKAJIANROZEO-UHFFFAOYSA-N 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 206010000087 Abdominal pain upper Diseases 0.000 description 2
- 235000013479 Amaranthus retroflexus Nutrition 0.000 description 2
- 201000000736 Amenorrhea Diseases 0.000 description 2
- 206010001928 Amenorrhoea Diseases 0.000 description 2
- 244000080208 Canella winterana Species 0.000 description 2
- 235000008499 Canella winterana Nutrition 0.000 description 2
- 240000005674 Ceanothus americanus Species 0.000 description 2
- 235000014224 Ceanothus americanus Nutrition 0.000 description 2
- 235000001904 Ceanothus herbaceus Nutrition 0.000 description 2
- 206010008190 Cerebrovascular accident Diseases 0.000 description 2
- 241000125183 Crithmum maritimum Species 0.000 description 2
- 206010013935 Dysmenorrhoea Diseases 0.000 description 2
- 208000012895 Gastric disease Diseases 0.000 description 2
- 206010023232 Joint swelling Diseases 0.000 description 2
- 208000037093 Menstruation Disturbances Diseases 0.000 description 2
- 206010027339 Menstruation irregular Diseases 0.000 description 2
- 240000007817 Olea europaea Species 0.000 description 2
- 206010033557 Palpitations Diseases 0.000 description 2
- 206010033799 Paralysis Diseases 0.000 description 2
- 241000013557 Plantaginaceae Species 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 241000218201 Ranunculaceae Species 0.000 description 2
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 2
- 208000006011 Stroke Diseases 0.000 description 2
- 208000033809 Suppuration Diseases 0.000 description 2
- 206010053615 Thermal burn Diseases 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 231100000540 amenorrhea Toxicity 0.000 description 2
- 210000000544 articulatio talocruralis Anatomy 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 208000001848 dysentery Diseases 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 239000003205 fragrance Substances 0.000 description 2
- 208000006278 hypochromic anemia Diseases 0.000 description 2
- 206010022437 insomnia Diseases 0.000 description 2
- 210000000629 knee joint Anatomy 0.000 description 2
- 201000005630 leukorrhea Diseases 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 201000002266 mite infestation Diseases 0.000 description 2
- 230000036565 night sweats Effects 0.000 description 2
- 206010029410 night sweats Diseases 0.000 description 2
- 230000008506 pathogenesis Effects 0.000 description 2
- 231100000915 pathological change Toxicity 0.000 description 2
- 230000036285 pathological change Effects 0.000 description 2
- 230000007170 pathology Effects 0.000 description 2
- 239000002304 perfume Substances 0.000 description 2
- 238000010791 quenching Methods 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 235000013599 spices Nutrition 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 230000035922 thirst Effects 0.000 description 2
- 201000004647 tinea pedis Diseases 0.000 description 2
- 239000011573 trace mineral Substances 0.000 description 2
- 235000013619 trace mineral Nutrition 0.000 description 2
- 206010046901 vaginal discharge Diseases 0.000 description 2
- 239000001993 wax Substances 0.000 description 2
- 239000002023 wood Substances 0.000 description 2
- MCSXGCZMEPXKIW-UHFFFAOYSA-N 3-hydroxy-4-[(4-methyl-2-nitrophenyl)diazenyl]-N-(3-nitrophenyl)naphthalene-2-carboxamide Chemical group Cc1ccc(N=Nc2c(O)c(cc3ccccc23)C(=O)Nc2cccc(c2)[N+]([O-])=O)c(c1)[N+]([O-])=O MCSXGCZMEPXKIW-UHFFFAOYSA-N 0.000 description 1
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 244000235603 Acacia catechu Species 0.000 description 1
- 206010063409 Acarodermatitis Diseases 0.000 description 1
- 241000553739 Aconitum carmichaelii var. truppelianum Species 0.000 description 1
- 241000826247 Aconitum flavum Species 0.000 description 1
- 240000002234 Allium sativum Species 0.000 description 1
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 241000256837 Apidae Species 0.000 description 1
- 241000256844 Apis mellifera Species 0.000 description 1
- 235000018062 Boswellia Nutrition 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 241000209507 Camellia Species 0.000 description 1
- 241000522254 Cassia Species 0.000 description 1
- 241000205571 Caulophyllum Species 0.000 description 1
- 208000010445 Chilblains Diseases 0.000 description 1
- 206010008528 Chillblains Diseases 0.000 description 1
- 206010008631 Cholera Diseases 0.000 description 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 1
- 244000192528 Chrysanthemum parthenium Species 0.000 description 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 1
- 206010010071 Coma Diseases 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 description 1
- 206010013911 Dysgeusia Diseases 0.000 description 1
- 208000005171 Dysmenorrhea Diseases 0.000 description 1
- 206010016952 Food poisoning Diseases 0.000 description 1
- 208000019331 Foodborne disease Diseases 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 206010019468 Hemiplegia Diseases 0.000 description 1
- 208000000616 Hemoptysis Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 206010019909 Hernia Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010061217 Infestation Diseases 0.000 description 1
- 241001571736 Lysimachia foenum-graecum Species 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 description 1
- 235000008708 Morus alba Nutrition 0.000 description 1
- 240000000249 Morus alba Species 0.000 description 1
- 206010028289 Muscle atrophy Diseases 0.000 description 1
- 240000009023 Myrrhis odorata Species 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 206010028817 Nausea and vomiting symptoms Diseases 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- 241000590428 Panacea Species 0.000 description 1
- 208000033952 Paralysis flaccid Diseases 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 241000218602 Pinus <genus> Species 0.000 description 1
- 241000758706 Piperaceae Species 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 206010061926 Purulence Diseases 0.000 description 1
- 208000004680 Rectal Fistula Diseases 0.000 description 1
- 241000447727 Scabies Species 0.000 description 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 1
- 206010040007 Sense of oppression Diseases 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 239000005864 Sulphur Substances 0.000 description 1
- 241001627955 Tetraodon lineatus Species 0.000 description 1
- 241001122767 Theaceae Species 0.000 description 1
- 206010043540 Thromboangiitis obliterans Diseases 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- 206010070863 Toxicity to various agents Diseases 0.000 description 1
- 206010053476 Traumatic haemorrhage Diseases 0.000 description 1
- 206010044546 Traumatic ulcer Diseases 0.000 description 1
- 206010044565 Tremor Diseases 0.000 description 1
- 208000037386 Typhoid Diseases 0.000 description 1
- 208000003443 Unconsciousness Diseases 0.000 description 1
- 208000024780 Urticaria Diseases 0.000 description 1
- 206010046910 Vaginal haemorrhage Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 230000035508 accumulation Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000004411 aluminium Substances 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 206010002156 anal fistula Diseases 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 230000000146 antalgic effect Effects 0.000 description 1
- 239000004410 anthocyanin Substances 0.000 description 1
- 229930002877 anthocyanin Natural products 0.000 description 1
- 235000010208 anthocyanin Nutrition 0.000 description 1
- 150000004636 anthocyanins Chemical class 0.000 description 1
- 230000002082 anti-convulsion Effects 0.000 description 1
- 230000003260 anti-sepsis Effects 0.000 description 1
- 201000007201 aphasia Diseases 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 208000034158 bleeding Diseases 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 210000003797 carpal joint Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000012174 chinese wax Substances 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 239000010941 cobalt Substances 0.000 description 1
- 229910017052 cobalt Inorganic materials 0.000 description 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 210000003792 cranial nerve Anatomy 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 230000009089 cytolysis Effects 0.000 description 1
- 238000007791 dehumidification Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 210000001513 elbow Anatomy 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 241001233957 eudicotyledons Species 0.000 description 1
- 230000005713 exacerbation Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 235000008384 feverfew Nutrition 0.000 description 1
- 208000028331 flaccid paralysis Diseases 0.000 description 1
- 210000002683 foot Anatomy 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 235000004611 garlic Nutrition 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 229930182478 glucoside Natural products 0.000 description 1
- 150000008131 glucosides Chemical class 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 208000021760 high fever Diseases 0.000 description 1
- 210000001624 hip Anatomy 0.000 description 1
- 210000004394 hip joint Anatomy 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000011229 interlayer Substances 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- 201000003265 lymphadenitis Diseases 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 239000011733 molybdenum Substances 0.000 description 1
- 229910052750 molybdenum Inorganic materials 0.000 description 1
- 230000020763 muscle atrophy Effects 0.000 description 1
- 201000000585 muscular atrophy Diseases 0.000 description 1
- 239000004084 narcotic analgesic agent Substances 0.000 description 1
- 201000009240 nasopharyngitis Diseases 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 239000008601 oleoresin Substances 0.000 description 1
- 229940126701 oral medication Drugs 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 230000003071 parasitic effect Effects 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 208000005687 scabies Diseases 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 210000002832 shoulder Anatomy 0.000 description 1
- 210000000323 shoulder joint Anatomy 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 235000015096 spirit Nutrition 0.000 description 1
- 201000005671 spondyloarthropathy Diseases 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 210000001226 toe joint Anatomy 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 231100000925 very toxic Toxicity 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 239000005335 volcanic glass Substances 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 210000000707 wrist Anatomy 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A61K31/125—Camphor; Nuclear substituted derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
- A61K35/10—Peat; Amber; Turf; Humus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Insects & Arthropods (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开一种治疗风湿病的回药外用制剂及其制备方法,该制剂由以下重量份的原料制成:党参10~30份,黄芪10~100份,生地10~100份,熟地10~30份,当归10~30份,川芎10~30份,桂枝10~30份,白芍10~30份,甘草10‑50份,透骨草10~30份,儿茶10~30份,白芥子10~60份,铁棒锤10~30份,草乌10~30份,零陵香10~30份,松香10~30份,樟脑10~30份,白芷10~30份,薄荷10~30份,乳香10~30份,没药10~30份,山茶10~30份,蜂蜡10~80份,火山泥50~300份,膏药基质50~200份,红花10~30份,阿魏10~30份,胡椒10~30份。本发明以补气血,调营卫为原则,注重突出回药香药的优势,芳香走窜之性,以温宣性、调理性、通络性,纠正禀性衰败,扶正祛邪,以治顽疾。因此,本发明制备的外用制剂具有补气血,通络强筋,活血化瘀,祛痰利湿,轻化骨刺,消肿止痛的功效。
Description
技术领域:
本发明属于回药技术领域,具体涉及一种治疗风湿病的回药外用制剂及其制备方法。
背景技术:
回族医学认为:禀性衰败是人体发生疾病的内在原因。所谓禀性衰败,是生命体为响应内外环境干扰与刺激,改变禀性气质体液机能应变能力的一种态势。在脑神经体液的统一调控下,使身心的生命活动维持在适度的弱的稳态状况。禀性衰败是对疾病过程中形质性智应变所处功能态势的概括,也反映出致病因素、疾病根源和禀性体液应变能力两个方面所处的状态和进一步变化的趋势。禀性衰败突出了身心在受到病因干扰刺激后,产生的生理病理变化以及抗病反映时的特定机能状态。禀性衰败不仅与四气(火、气、土、水)相互关联,为禀性衰败定质;而且与四性(热、冷、湿、干)关系密切,为禀性衰败定性。
风湿类疾病是由于禀性衰败寒热夹杂体质异常所致,具体说是寒性、湿性禀性体质,是感受隐潜性的现显性的致病因素,导致具体液质分泌异常(或称黑血根源)或白体液异常“沉淀”而产生的异常,黑白血质及湿浊根源自“脑”随经脉流向关节筋骨等处所引起的病征。回族医学之体液病现与疾病根源说,认为“黑浊血根源”和“浊痰”、湿浊根源多为风湿类疾病的病理依据。因此,风湿类疾病的病理根源与气血变化有关,如“动之于四肢百骸者,气与血兼行之事”,即四肢骨筋的正常或病理变化亦与气血的质量、虚实与运行相关,故在治疗过程多与外气血、活血药配伍施治。
目前,治疗风湿类疾病采用中、西药口服治疗非常常见,中医主要多以祛痰湿,益肝肾,补气血为主要治疗原则,对风湿类疾病的防治取得了一定的效果,但基于中回医融合,用于治疗风湿类疾病的回药制剂,临床尚属少见。鉴于此,针对风湿病的病因病机,在中回医理论指导下,以扶正祛病,养气血,调营卫,改善体质禀性衰败之根源为其主要的治疗原则,提供一种治疗风湿病的回药外用制剂及其制备方法。
发明内容:
本发明的目的旨在根据回族医药理论,提供一种治疗风湿类疾病的回药外用制剂及其制备方法。
为达到上述目的,本发明采取以下技术方案:
一种治疗风湿病的回药外用制剂,由以下重量份的原料制成:党参10~30份,黄芪10~100份,生地10~100份,熟地10~30份,当归10~30份,川芎10~30份,桂枝10~30份,白芍10~30份,甘草10-50份,透骨草10~30份,儿茶10~30份,白芥子10~60份,铁棒锤10~30份,草乌10~30份,零陵香10~30份,松香10~30份,樟脑10~30份,白芷10~30份,薄荷10~30份,乳香10~30份,没药10~30份,山茶10~30份,蜂蜡10~80份,火山泥50~300份,膏药基质50~200份,红花10~30份,阿魏10~30份,胡椒10~30份。
上述治疗风湿病的回药外用制剂的制备方法,包括如下步骤:
1)按重量份称取党参、黄芪、生地、熟地、当归、川芎、桂枝、白芍、甘草、透骨草、儿茶、铁棒锤、草乌、胡椒、阿魏、乳香、没药、樟脑,分别粉碎后混合极细,备用;
2)按重量份称取零陵香、松香、白芷、薄荷、山茶、红花、白芥子,分别萃取制成精油,备用;
3)按重量份称取蜂蜡、膏药基质、火山泥、天然发热剂加热后,与步骤1)和步骤2)制备的混合物混匀,即得所述的回药外用制剂。
上述步骤1)中粉碎采用超微粉碎将原料制成超微粉,便于皮肤经脉吸收,充分发挥香药透皮走窜功能。
本发明各原料的药理性能及功效作用如下:
党参,为菊科多年生草本植物,以根茎入药,味甘性平,以条粗大,皮松肉紧,横纹多,质地柔韧,有香气,味甜者为佳。主治:补中益气。
黄芪,性味甘,微温,补气升阳、益卫固表、托毒生肌、利水退肿,具有治疗肺脾气虚,中气下陷,气虚血滞导致肢体麻木,关节痹痛,半身不遂,气虚津亏的消渴等症。
生地,为玄参科植物地黄的块根。味甘,性寒,归心,肝,肾经。具有清热凉血、益阴生津之功效。用于温热病热入营血,壮热神昏,口干舌绛,如清营汤。
熟地,为玄参科植物地黄的块根。味甘,微温。归肝、肾经。具有补血滋阴功效,可用于血虚萎黄,眩晕,心悸失眠,***,崩漏等症,亦可用于肾阴不足的潮热骨蒸、盗汗、遗精、消渴等症。
当归,味甘、辛,性温,归肝、心、脾经。有补血活血,调经止痛,润肠通便之功。其甘润以补血,辛散温通以活血,“诚为血中之气药,亦血中之圣药。”还能散寒止痛,可治疗血虚、血寒、血瘀所致的虚寒腹痛,风湿痹痛。
川芎,为伞形科植物川芎的根茎。味辛,性温。入肝、胆经。常用于活血行气,祛风止痛,川芎辛温香燥,走而不守,既能行散,上行可达巅顶;又入血分,下行可达血海。活血祛瘀作用广泛,适宜瘀血阻滞各种病症;祛风止痛,效用甚佳,可治头风头痛、风湿痹痛等症。昔人谓川芎为血中之气药,殆言其寓辛散、解郁、通达、止痛等功能。
桂枝,为樟科植物肉桂的干燥嫩枝。性味辛、甘,温,入肺、心、膀胱经,是主治里寒常用的温里药,具有补元阳、通血脉、暖脾胃之功效。用于风寒感冒,脘腹冷痛,血寒经闭,关节痹痛,痰饮,水肿,心悸,奔豚。
白芍,为毛莨科植物芍药的干燥根。平肝止痛,养血调经,敛阴止汗。用于头痛眩晕,胁痛,腹痛,四肢挛痛,血虚萎黄,***,自汗,盗汗。
甘草,味甘,性微寒。益气补中,缓急止痛,祛痰止咳,消热解毒,调和诸药。用于脾胃虚弱,怠食乏力,心悸气短,咳嗽痰多,脘腹、四肢挛急疼痛,痈肿疮毒,缓解药物毒性、烈性。又可用于阴血不足、筋失所养、四肢挛急、转筋疼痛。还有缓和药性、调和百药之功。
透骨草,为伞形菊科植物。味苦,微甘、辛,性寒。具有祛风除湿、活血止痛、消肿痛经、软坚功能。有治疗慢性风湿性关节炎疗效。
儿茶,为豆科植物儿茶的去皮枝、干的干燥煎膏。味苦、涩,微寒。归肺、心经。具有活血止痛,止血生肌,收湿敛疮,清肺化痰的功效。用于跌扑伤痛,外伤出血,吐血衄血,疮疡不敛,湿疹、湿疮,肺热咳嗽。
白芥子,为十字花科植物白芥的种子。《回回药方》称“白西盘丹”。性温,味辛。有利气豁痰、温中散寒、通络止痛之功效。用治痰饮咳喘、胸胁胀满疼痛、反胃呕吐、中风不语、肢体痹痛麻木、脚气、阴疽、肿毒、跌打肿痛。
铁棒锤,为毛茛科植物铁棒锤和伏毛铁棒锤的块根。苦辛,热,有大毒。活血祛瘀,驱风除湿,止痛消肿。主治跌打损伤,风湿关节痛,牙痛,食积腹痛,妇女痛经,痈肿,冻疮。
草乌,为毛茛科植物北乌头的干燥块根。味辛、苦,性热。归心、肝、肾、脾经。祛风除湿,温经止痛。用于风寒湿痹,关节疼痛,心腹冷痛,寒疝作痛及麻醉止痛。
零陵香,为双子叶植物药报春花科植物灵香草的带根全草。味甘,平,无毒。具有祛风的功效。主治伤寒、感冒头痛,胸腹胀满,下利,遗精,鼻塞,牙痛。
松香,为松科松属若干植物中渗出的油树脂,经蒸馏或提取除去挥发油后所余固体树脂。味苦、甘,性温。归肝、脾经。具有祛风燥湿,排脓拔毒,生肌止痛之功效。常用于痈疽恶疮,瘰疬,痿症,疥癣,白秃,疠风,痹症,金疮,扭伤,妇女白带,血栓闭塞性脉管炎。
樟脑,为樟科植物樟的根、干、枝、叶,经提炼制成的颗粒状结晶。《回回药方》称“马可夫儿”、“可福黎”、“可福而”。味辛,性热。有通窍、杀虫、止痛、辟秽之功效。用治心腹胀痛、脚气、疮疡疥癣、牙痛、跌打损伤。涂于皮肤,有温和的刺激及防腐、镇痛、止痒作用。少量口服有驱风及轻微祛痰作用。
白芷,性温,味辛,气芳香,微苦。祛风湿,活血排脓,生肌止痛。用于头痛、牙痛、鼻渊、肠风痔漏、赤白带下、痈疽疮疡、皮肤瘙痒。
薄荷,为唇形科植物香薄荷或家薄荷的全草或叶。《回回药方》称“麻而桑哥失”、“木失其他剌迷石亦”。味辛,性凉。有疏风、散热、辟秽、解毒之功效。用治外感风热、头痛目赤、咽喉肿痛、食滞气胀、血疮、牙痛、疮疥、瘾疹。该药性升,在回族医学中属于“宣药”,上清头目浊风,治头痛、眩晕、发热;又祛浊风恶痰,治中风左瘫右痪、癫痫及伤风咳嗽、脑楼鼻渊。
乳香,为橄榄科植物卡氏乳香树及同属其他植物树干皮部切伤后渗流出的油胶树脂。《回回药方》称“滴乳”、“木瓦”、“捆都而”。性温,味辛、苦。有活血止痛、消肿生肌之功效。用治血瘀气滞的脘腹疼痛、痛经、经闭以及跌打损伤和痈疽疼痛。因其活血止痛作用良好,兼能行气,亦用治气血凝滞之疼痛,同没药合用,能增强活血止痛功效。还用于外科疮疡溃破久不收口等。
没药,为橄榄科植物没药树的树脂。《回回药方》称“木儿”、“木里叶”。性平,味苦。有活血行气、止痛、生肌之功效,并有兴奋、收敛与防腐作用。用途与乳香类同。
山茶,含有花白甙及花色甙等敛止血剂,有止血、散瘀消肿之功用,主治咳血、鼻出血、肠胃山血、子宫出血以及烧伤、烫伤、跌打损伤、创伤出血等症。
蜂蜡,为蜜蜂科昆虫蜜蜂等分泌的蜡质,经精制而成。又名“蜜蜡”,有黄蜡、白蜡二种。味甘淡,性平。有解毒、生肌定痛之功效。用治急心痛、下痢脓血、久泻不止、胎动下血、疮痈内攻、久溃不敛、水火烫伤。该药味淡,性啬而质坚,不仅疗久泄下痢,亦可贴疮生肌止痛。
火山泥,是火山的产物,是以火山玻璃为主要成分的深灰到黑色的无黏性泥。火山泥蕴含三十多种微量元素和矿物质:硅、铝、镁、钙、铁、钛、硫、磷、钠、铜、锌、硒、钴、锰、钼等。古人把火山泥涂抹在衣服夹层上,经常穿着可以强筋健骨,预防风湿等疾病。由于火山泥的多种成分渗入人体内部,对于缓解疲劳,减轻压力,消除疼痛有非常好的效果。
红花,味辛,性温。入心、肝经。具有活血通经,散瘀止痛的功效,有助于治经闭、痛经、恶露不行、胸痹心痛、瘀滞腹痛、胸胁刺痛、跌打损伤、疮疡肿痛疗效。
阿魏,为伞形科植物阿魏的树脂。《回回药方》称“黑黎提提”、“安古丹”。性微温,味辛,具有强烈而持久的蒜样特异臭气。有消积、杀虫、解毒之功效。用治痞块、积食、虫积、胸腹胀痛、疟疾、痢疾。国外有用其抗惊厥,治疗某些精神病。亦有作驱虫、驱风及刺激性祛痰剂。多用于痛经止痛、去风寒、强筋健脑。
胡椒,为胡椒科植物胡椒的果实。《海药本草》:“多食,损肺,令人吐血。”“去胃口虚冷气,宿食不消,霍乱气逆,心腹卒痛,冷气上冲。”本品温中、下气、消痰、解毒。用治寒痰食积、脘腹冷痛、反胃、呕吐清水、泄泻、冷痢,并解食物中毒。
本发明的各个原料以补气血,调营卫为主要原则,注重突出回药香药的优势,芳香走窜之性,以温宣性、调理性、通络性,纠正禀性衰败,扶正祛邪,以治顽疾。因此,本发明制备的外用制剂具有补气血,通络强筋,活血化瘀,祛痰利湿,轻化骨刺,消肿止痛的功效。较现有技术,本发明的优势在于:
(1)针对风湿病的病因病机,本发明的组方是在中回医理论指导,扶正祛病,养气血,调营卫,改善体质禀性衰败之根源,达到治疗疾病的目的。配方中首先以黄芪四物汤加减,滋养气血,调和营卫,恢复禀性正气;以铁棒锤、透骨草、红花、乳香等拔膏化瘀,祛除风湿寒瘀痰毒邪;配伍零陵香、松香、白芷、白芥子等香药,以其透皮浸肌之属性,使药力直达病所,使以火山泥、蜂蜡、发热剂加强组分的功力和疗效,使邪毒通过皮肤排除体外;
(2)以中医“正气存内,邪不干”之学说,和回医禀性衰败学说对风湿病的认识,中回医融合,以扶正为生,应运外用制剂治疗风湿病,临床尚属少见;
(3)利用超微粉碎技术,将主要原料制成超微粉,便于皮肤经脉吸收,充分发挥香药透皮走窜功能,再以火山泥、蜂蜡、天然发热剂加强其功能,使药性药力直达病所,三合一其功力倍增,亦属创新。
具体实施方式:
下面结合具体实施方式及其治病例对本发明的技术方案进行详细说明。
实施例1
按重量份计,称取党参25份,黄芪60份,生地60份,熟地15份,当归20份,川芎15份,桂枝15份,白芍20份,甘草30份,透骨草20份,儿茶20份,铁棒锤15份,草乌15份,胡椒20份,阿魏20份,乳香15份,没药15份,樟脑20份,分别采用超微粉碎制成超微粉后混合极细,备用;然后,称取零陵香15份,松香15份,白芷20份,薄荷15份,山茶20份,红花20份,白芥子45份,分别进行萃取制成精油,备用;最后,称取蜂蜡50份,火山泥250份,膏药基质150份,加入天然发热剂加热后,与上述超微粉混合物和制备的精油混合物混匀,即得治疗风湿病的回药外用制剂。
实施例2
按重量份计,称取党参10份,黄芪80份,生地80份,熟地10份,当归30份,川芎10份,桂枝30份,白芍10份,甘草50份,透骨草10份,儿茶10份,铁棒锤30份,草乌10份,胡椒30份,阿魏10份,乳香30份,没药10份,樟脑30份,分别采用超微粉碎制成超微粉后混合极细,备用;然后,称取零陵香10份,松香30份,白芷10份,薄荷30份,山茶10份,红花30份,白芥子60份,分别进行萃取制成精油,备用;最后,称取蜂蜡20份,火山泥200份,膏药基质100份,加入天然发热剂加热后,与上述超微粉混合物和制备的精油混合物混匀,即得治疗风湿病的回药外用制剂。
实施例3
按重量份计,称取党参30份,黄芪25份,生地35份,熟地30份,当归10份,川芎30份,桂枝10份,白芍30份,甘草10份,透骨草30份,儿茶30份,铁棒锤10份,草乌30份,胡椒10份,阿魏30份,乳香10份,没药30份,樟脑10份,分别采用超微粉碎制成超微粉后混合极细,备用;然后,称取零陵香30份,松香10份,白芷30份,薄荷10份,山茶30份,红花10份,白芥子15份,分别进行萃取制成精油,备用;最后,称取蜂蜡80份,火山泥100份,膏药基质200份,加入天然发热剂加热后,与上述超微粉混合物和制备的精油混合物混匀,即得治疗风湿病的回药外用制剂。
实施例4
按重量份计,称取党参15份,黄芪65份,生地75份,熟地15份,当归25份,川芎15份,桂枝25份,白芍15份,甘草25份,透骨草15份,铁棒锤25份,草乌15份,胡椒25份,阿魏15份,乳香25份,没药15份,樟脑25份,分别采用超微粉碎制成超微粉后混合极细,备用;然后,称取零陵香15份,松香25份,白芷15份,薄荷25份,山茶15份,红花25份,白芥子15份,分别进行萃取制成精油,备用;最后,称取蜂蜡55份,火山泥150份,膏药基质150份,加入天然发热剂加热后,与上述超微粉混合物和制备的精油混合物混匀,即得治疗风湿病的回药外用制剂。
实施例5
按重量份计,称取党参20份,黄芪100份,生地100份,熟地20份,当归10份,川芎20份,桂枝15份,白芍20份,甘草30份,透骨草10份,铁棒锤20份,草乌15份,胡椒20份,阿魏25份,乳香10份,没药15份,樟脑25份,分别采用超微粉碎制成超微粉后混合极细,备用;然后,称取零陵香10份,松香25份,白芷20份,薄荷25份,山茶15份,红花20份,白芥子10份,分别进行萃取制成精油,备用;最后,称取蜂蜡40份,火山泥300份,膏药基质50份,加入天然发热剂加热后,与上述超微粉混合物和制备的精油混合物混匀,即得治疗风湿病的回药外用制剂。
实施例1~实施例5制备的治疗风湿病的回药外用制剂的使用方法:涂抹前于微波炉中加热2~5分钟,取药膏适量均匀的涂抹在患部,然后用薄膜包裹患部保持30~60分钟后,取下薄膜即为一次;每三天一次,依患者的患病情况,持续涂抹3~5次为一个疗程。
临床应用的效果:
治病例1:
王先生,年纪52岁,患风湿性关节炎(颈椎病),治疗前症状:全身怕冷、关节游走性疼痛,以肩、肘、腕、膝、髋、踝关节等大关节为主,遇热疼痛减轻,遇冷疼痛加重,又出现颈部僵硬、活动受限,相继出现头晕、头痛、失眠、耳鸣及双手麻木,夜间较为明显,患者耳廓***变薄,压痛阳性。经过按上述实施例1制备的外用制剂使用每三天涂抹一次,经过三个疗程30天的治疗后,患者双手麻木症状消失,关节疼痛明显减轻,活动自如,身体恢复正常。
治病例2:
张女士,49岁,患风湿性关节炎。患者全身关节间断性疼痛已有4-5年,后因劳累、受凉后出现颈椎关节、腰椎关节、双膝关节及左侧足跟关节疼痛加重,活动受限,并伴有头晕、头痛、双手麻木、迎风脸麻等。经过按上述实施例2制备的外用制剂使用每三天涂抹一次,经过四个疗程60天的治疗后,患者双脚麻木症状消失,关节疼痛减轻,活动自如,身体恢复正常。
治病例3:
陈女士,22岁,患类风湿性关节炎。患者全身关节肿痛,面色苍白,浮肿,双手关节肿胀,双肘关节肿痛,肩关节肿痛,双脚趾及踝关节肿痛,压痛均明显;双侧膝关节肿痛,曲伸不利,不能下蹲,影响大小便;脊柱关节,双侧髋关节均肿痛,生活不能自理。经过按上述实施例3制备的外用制剂使用每三天涂抹一次,经过三个疗程45天的治疗后,患者全身关节疼痛明显减轻,水肿完全消失,可以独立行走,蹲起,翻身各关节活动不再受限,生活能自理,半年复诊基本痊愈。
治病例4:
孙先生,45岁,患类风湿性关节炎。患者面容憔悴、精神萎靡、身体消瘦,查体时,全身关节疼痛明显,双肩关节不能抬起,双膝关节肿痛,不能下蹲,全身肌肉萎缩,生活不能自理。经过按上述实施例3制备的外用制剂使用每三天涂抹一次,经过三个疗程45天的治疗后,患者关节疼痛明显好转,生活完全自理。
治病例5:
杨女士,49岁,患类风湿性关节炎。患者全身肿胀,面色苍白、浮肿,神情沮丧,缓慢步行,查体时:双手腕关节肿痛以及指间关节呈梭形肿胀,压痛明显;双侧膝关节肿痛,下蹲困难;肩关节疼痛,双上臂不能抬起,梳头、穿衣需家人帮助;全身骨关节均压痛明显。经过按上述实施例3制备的外用制剂使用每三天涂抹一次,经过四个疗程40天的治疗后,患者病情明显好转,全身关节疼痛消失,患者面色红润,精神饱满。
据临床资料统计:使用本发明制备的治疗风湿病的回药外用制剂第一疗程明显好转,自觉症状明显减轻,显效率达95%以上,随着疗程增加,根据不同患者的情况,三、四个疗程后疼痛、麻木感消失,病人恢复正常,活动自如,总治愈率可达到80%以上。
Claims (5)
1.一种治疗风湿病的回药外用制剂,其特征在于:由以下重量份的原料制成:党参10~30份,黄芪10~100份,生地10~100份,熟地10~30份,当归10~30份,川芎10~30份,桂枝10~30份,白芍10~30份,甘草10-50份,透骨草10~30份,儿茶10~30份,白芥子10~60份,铁棒锤10~30份,草乌10~30份,零陵香10~30份,松香10~30份,樟脑10~30份,白芷10~30份,薄荷10~30份,乳香10~30份,没药10~30份,山茶10~30份,蜂蜡10~80份,火山泥50~300份,膏药基质50~200份,红花10~30份,阿魏10~30份,胡椒10~30份。
2.根据权利要求1所述的治疗风湿病的回药外用制剂,其特征在于:由以下重量份的原料制成:党参25份,黄芪60份,生地60份,熟地15份,当归20份,川芎15份,桂枝15份,白芍20份,甘草30份,透骨草20份,儿茶20份,白芥子45份,铁棒锤15份,草乌15份,零陵香15份,松香15份,樟脑20份,白芷20份,薄荷15份,乳香15份,没药15份,山茶20份,蜂蜡50份,火山泥250份,膏药基质150份,红花20份,阿魏20份,胡椒20份。
3.根据权利要求1所述的治疗风湿病的回药外用制剂,其特征在于:由以下重量份的原料制成:党参30份,黄芪25份,生地35份,熟地30份,当归10份,川芎30份,桂枝10份,白芍30份,甘草10份,透骨草30份,儿茶30份,白芥子15份,铁棒锤10份,草乌30份,零陵香30份,松香10份,樟脑10份,白芷30份,薄荷10份,乳香10份,没药30份,山茶30份,蜂蜡80份,火山泥100份,膏药基质200份,红花10份,阿魏30份,胡椒10份。
4.根据权利要求1、2或3所述的治疗风湿病的回药外用制剂的制备方法,其特征在于:包括如下步骤:
1)按重量份称取党参、黄芪、生地、熟地、当归、川芎、桂枝、白芍、甘草、透骨草、儿茶、铁棒锤、草乌、胡椒、阿魏、乳香、没药、樟脑,分别粉碎后混合极细,备用;
2)按重量份称取零陵香、松香、白芷、薄荷、山茶、红花、白芥子,分别萃取制成精油,备用;
3)按重量份称取蜂蜡、膏药基质、火山泥、天然发热剂加热后,与步骤1)和步骤2)制备的混合物混匀,即得所述的回药外用制剂。
5.根据权利要求4所述的治疗风湿病的回药外用制剂的制备方法,其特征在于:所述步骤1)中粉碎采用超微粉碎技术将原料制成超微粉。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710457897.4A CN107158154A (zh) | 2017-06-16 | 2017-06-16 | 一种治疗风湿病的回药外用制剂及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710457897.4A CN107158154A (zh) | 2017-06-16 | 2017-06-16 | 一种治疗风湿病的回药外用制剂及其制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN107158154A true CN107158154A (zh) | 2017-09-15 |
Family
ID=59819728
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710457897.4A Pending CN107158154A (zh) | 2017-06-16 | 2017-06-16 | 一种治疗风湿病的回药外用制剂及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN107158154A (zh) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1433782A (zh) * | 2002-01-22 | 2003-08-06 | 康长生 | 一种治疗风寒湿痹痛的外用药物的配方及制备方法 |
CN102266398A (zh) * | 2011-07-07 | 2011-12-07 | 夏军秀 | 一种泥灸风湿疾病的组合物 |
CN104436103A (zh) * | 2014-11-06 | 2015-03-25 | 王全文 | 一种外用追风透骨贴及其制备方法 |
CN104758382A (zh) * | 2014-04-15 | 2015-07-08 | 河南中医学院 | 一种治疗风湿病的中药组合物、软膏剂及其制备方法 |
-
2017
- 2017-06-16 CN CN201710457897.4A patent/CN107158154A/zh active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1433782A (zh) * | 2002-01-22 | 2003-08-06 | 康长生 | 一种治疗风寒湿痹痛的外用药物的配方及制备方法 |
CN102266398A (zh) * | 2011-07-07 | 2011-12-07 | 夏军秀 | 一种泥灸风湿疾病的组合物 |
CN104758382A (zh) * | 2014-04-15 | 2015-07-08 | 河南中医学院 | 一种治疗风湿病的中药组合物、软膏剂及其制备方法 |
CN104436103A (zh) * | 2014-11-06 | 2015-03-25 | 王全文 | 一种外用追风透骨贴及其制备方法 |
Non-Patent Citations (1)
Title |
---|
魏澜涛: "中西医结合治疗类风湿性关节炎临床观察", 《实用中医内科杂志》 * |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN105708612B (zh) | 扁鹊砭石能量泥基质、含有该基质的扁鹊砭石能量泥及其制作方法 | |
CN106421649A (zh) | 一种治疗脑中风的中药组合物及其制备方法 | |
CN103638250B (zh) | 一种治疗面神经***中药制剂及其制备方法 | |
CN103705670A (zh) | 一种祛风除湿止痛的中药及其制备方法 | |
CN103768567A (zh) | 一种黑膏药及其制备方法 | |
CN103316146A (zh) | 一种麻醉用中药制剂 | |
CN105560748A (zh) | 一种拔毒膏及其制备方法 | |
CN103893670B (zh) | 一种治疗心脑血管病的中药药丸 | |
CN102008674B (zh) | 一种治疗椎间盘突出、骨质增生和类风湿的膏药及其制备方法 | |
CN106880826A (zh) | 一种治疗慢性心力衰竭的中药制剂及其制备方法 | |
CN104173957A (zh) | 一种抗衰延年膏药 | |
CN108671095A (zh) | 一种缓解眼部不适症的中药组合物、中药液的制备方法及中药制剂贴片 | |
CN101766799A (zh) | 参附蜈蚣保健酒 | |
CN105412864A (zh) | 一种用于治疗腰椎间盘突出症的祛痛膏 | |
CN104623532A (zh) | 一种治疗脑胶质瘤的中药组合物及其制备方法 | |
CN104840773A (zh) | 治疗椎动脉型颈椎病的中药组合物及制法 | |
CN109464640A (zh) | 调理脱发重生白发转黑的食用药物及其制备方法 | |
CN107158154A (zh) | 一种治疗风湿病的回药外用制剂及其制备方法 | |
CN104257986A (zh) | 一种治疗肾炎的中药 | |
CN103055172A (zh) | 一种治疗白癜风的中药组合 | |
CN107441278A (zh) | 药物组合物、药物制剂及其制备方法和应用 | |
CN108114112A (zh) | 一种化瘀止痛膏及其制备方法 | |
CN107115391A (zh) | 一种中药醋生铁落敷灸 | |
CN104940870B (zh) | 治疗产后无奶症的中药组合物及其制备方法 | |
CN104606605A (zh) | 一种治疗乳腺增生的中药组合物及其制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170915 |
|
RJ01 | Rejection of invention patent application after publication |