CN107149662A - 一种治疗纳呆的新型中药组合物及其制备方法 - Google Patents
一种治疗纳呆的新型中药组合物及其制备方法 Download PDFInfo
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Abstract
本发明属于中药制剂领域,目的是根据中医对纳呆的认识机理而提供的一种治疗纳呆的新型中药组合物,所述中药组合物的各个组分及其质量份比如下:苏合香、安息香、沙参、零陵香、石菖蒲、冰片、麦冬(去心)、樟脑、神曲、生黄芪、当归、山药、生地黄、炒麦芽、莱菔子、焦槟榔、谷芽、甘草、焦山楂、鸡内金(炒)、陈皮、枳实(炒)、川楝子、沉香、檀香、香附子、玫瑰花、九香虫、木香、厚朴、砂仁、桑叶、黄连、大黄;本发明提供的药物是一个标本兼治的中药组方。
Description
技术领域
本发明属于中药制剂领域,具体涉及一种治疗纳呆的新型中药组合物,特别是供纳呆患者使用的新型中药组合物及其制备方法的领域。
背景技术
胃的受纳功能呆滞,故名纳呆,也称“胃呆”。即消化不良、食欲不振的症状。如果胃口不好,常有饱滞之感的,称为“胃纳呆滞”。纳呆是消化***常见疾病之一,表现为食欲不振,不思饮食,饮食减少,不饥不纳,或食不知味等。引起纳呆的原因很多,外感六淫、内伤脏腑都可导致脾胃运化功能失调,出现纳呆。随着现代社会生活方式的改变,近年临床发病率有不断的上升趋势。
那么,就如何找到一种可有效治疗纳呆的新型中药组合物,是我们目前急需要解决的问题。
发明内容
随着我国中医中药学的不断发展,在治疗纳呆上,人们逐渐意识到了中医治疗纳呆的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗纳呆的现状,本发明的目的是在于提供一种治疗纳呆的新型中药组合物,以解决纳呆患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及质量份比,可有效治疗上述纳呆。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种治疗纳呆的新型中药组合物及其制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
苏合香3~10g、安息香3~16g、沙参100~160g、零陵香100~160g、石菖蒲30~100g、冰片3~6g、麦冬(去心)6~16g、樟脑0.6~2g、神曲100~160g、生黄芪100~260g、当归80~160g、山药150~350g、生地黄100~360g、炒麦芽100~160g、莱菔子50~100g、焦槟榔30~100g、谷芽100~160g、甘草30~120g、焦山楂100~120g、鸡内金(炒)50~160g、陈皮30~160g、枳实(炒)50~120g、川楝子50~90g、沉香30~60g、檀香15~30g、香附子50~120g、玫瑰花30~300g、九香虫30~100g、木香30~100g、厚朴30~100g、砂仁30~70g、 桑叶50~120g、黄连30~60g、大黄50~220g。
一种治疗纳呆的新型中药组合物及其制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
苏合香5~9g、安息香6~14g、沙参115~140g、零陵香115~140g、石菖蒲35~90g、冰片3.5~5.5g、麦冬(去心)10~14g、樟脑0.8~1.8g、神曲115~140g、生黄芪115~230g、当归90~140g、山药170~300g、生地黄115~300g、炒麦芽115~140g、莱菔子60~90g、焦槟榔35~90g、谷芽115~140g、甘草35~105g、焦山楂115~105g、鸡内金(炒)60~140g、陈皮35~140g、枳实(炒)60~105g、川楝子60~80g、沉香35~50g、檀香18~25g、香附子60~105g、玫瑰花35~260g、九香虫35~90g、木香35~90g、厚朴35~90g、砂仁35~60g、 桑叶60~105g、黄连35~50g、大黄60~200g。
一种治疗纳呆的新型中药组合物及其制备方法,其特征在于,所述“最佳方案”的中药组合物的各个组分及其质量份比如下所示:
苏合香8g、安息香12g、沙参120g、零陵香120g、石菖蒲80g、冰片5g、麦冬(去心)12g、樟脑1.5g、神曲120g、生黄芪200g、当归120g、山药260g、生地黄260g、炒麦芽120g、莱菔子80g、焦槟榔80g、谷芽120g、甘草95g、焦山楂95g、鸡内金(炒120g、陈皮120g、枳实(炒)90g、川楝子70g、沉香45g、檀香22g、香附子95g、玫瑰花230g、九香虫80g、木香80g、厚朴80g、砂仁50g、桑叶95g、黄连45g、大黄170g。
一种治疗纳呆的新型中药组合物及其制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、将上述原料中药拣去杂质、粉尘及干燥后,按照质量份比共研为极细末待用;
B、按照传统制备中药水丸剂的方法,将研磨好的极细末药物过筛后,放入药器中混合拌均,然后制备成水丸剂(其水丸的粒度为:(4.9mm~5.0mm),进而晒干,分装密封即可。
一种治疗纳呆的新型中药组合物及其制备方法,其特征在于,所述服用方法为:将制备好的水丸剂药物以每日三次服用,早中晚各服一次,给药量6g /次,温开水送下。一个月为一疗程,服药2~3.5个疗程即可痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及其中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
苏合香,性味:辛、甘、温,无毒,具有通窍辟秽、开郁豁痰、行气止痛之功效,用于治疗中风、痰厥、气厥之寒闭症、温疟、惊痫、湿浊吐利、心腹卒痛以及冻疮、疥癣等症;
安息香,性味:辛、苦、性平,具有开窍醒神、豁痰辟秽、行气活血、止痛之功效,用于治疗中风痰劂、惊痫昏迷、产后血晕、心腹疼痛、风痹肢节痛;
沙参,性味:味甘、微苦、性微寒,具有养阴清热、润肺化痰、益胃生津之功效,用于治疗阴虚久咳、痨嗽痰血、燥咳痰少、虚热喉痹、津伤口渴;
零陵香,性味:辛、甘、性平,具有解表、止痛、行气、驱蛔之功效,用于治疗感冒头痛、咽喉肿痛、牙痛、胸腹胀满、蛔虫病等症;
石菖蒲,性味:辛、苦、温,具有化湿开胃、开窍豁痰、醒神益智之功效,用于治疗脘痞不饥、噤口下痢、神昏癫痫、健忘耳聋等症;
冰片,性味:辛、苦、微寒,具有开窍醒神、清热止痛之功效,用于治疗热病神昏、痉厥、中风痰厥、气郁暴厥、中恶昏迷、目赤、口疮、咽喉肿痛、耳道流脓等症;
麦冬(去心),性味:甘、微苦微寒,具有养阴润肺、益胃清心之功效,用于治疗阴虚肺燥、干咳痰稠、劳嗽咯血、津少口渴、心烦失眠、肠燥便秘;
樟脑,性味:辛、热,有小毒,具有通关窍、利滞气、辟秽浊、杀虫止痒、消肿止痛之功效,用于治疗热病神昏、中恶猝倒、痧胀吐泻腹痛、寒湿脚气、疥疮顽癣、秃疮、冻疮、臁疮、水火烫伤、跌打伤痛、牙痛、风火赤眼;
神曲,性味:甘、辛、温,无毒,具有健脾和胃、消食化积之功效,用于治疗饮食停滞、消化不良、脘腹胀满、食欲不振、呕吐泻痢;
生黄芪,性味:味甘、微温,具有补气固表、托疮生肌、利水之功效,用于治疗气血虚弱、自汗、久泻脱肛、子宫脱垂、肾炎浮肿、蛋白尿、糖尿病、慢性溃疡;
当归,性味:性温、味甘辛, 具有补血和血、调经止痛、润燥滑肠之功效,用于治疗血虚、面色萎黄、眩晕心悸、血虚、或兼有瘀滞的***、经闭、痛经、虚寒性腹痛、冠心病心绞痛、风湿痹痛、跌打损伤;
山药,性味:甘、平,具有补脾养胃、生津益肺、补肾涩精的功效,用于治疗脾虚食少、久泻不止、肺虚喘咳、肾虚遗精、带下、尿频、虚热消渴,麸炒山药补脾健胃,用于脾虚食少、泄泻便溏,白带过多;
生地黄,性味:味甘、苦、性寒,具有清热、凉血之功效,用于治疗温热病热入营血、壮热神昏、口干舌绛;
炒麦芽,性味:甘、平,具有行气消食,健脾开胃,退乳消胀之功效,用于治疗食积不消、脘腹胀痛、脾虚食少、乳汗郁积、***胀痛、妇女断乳;
莱菔子,性味:味辛、甘、性平,具有消食导滞、降气化痰之功效,用于治疗食积气滞、脘腹胀满、腹泻、下痢后重、咳嗽多痰、气逆喘满;
焦槟榔,性味:苦、辛、温,具有消食导滞之功效,用于治疗食积不消、泻痢后重;
谷芽,性味:甘、平,具有消食化积、健脾开胃之功效,用于治疗食品店积停滞、胀满泄泻、脾虚少食、脚气浮肿;
甘草,性味:甘、平,具有益气补中、缓急止痛、润肺止咳、泻火解毒、调和诸药之功效,用于治疗倦怠食少、肌瘦面黄、心悸气短、腹痛便溏、四肢挛急疼痛、脏躁、咳嗽气喘、咽喉肿痛、痈疮肿痛、小儿胎毒及药物、食物中毒;
焦山楂,性味:酸、甘、微温,具有消食健胃,行气散瘀之功效,用于治疗肉食积滞、胃脘胀满、泻痢腹痛、瘀血经闭、产后瘀阻、心腹刺痛、疝气疼痛、高脂血症,焦山楂消食导滞作用增强,用于肉食积滞、泻痢不爽;
鸡内金(炒),性味:味甘、性平,具有健脾消食、涩精止遗、消症化石之功效,用于治疗消化不良、饮食积滞、呕吐反胃、泄泻下痢、小儿疳积、遗精、遗尿、小便频数、泌尿系结石及胆结石、症瘕经闭、喉痹乳蛾、牙疳口疮;
陈皮,性味:味辛、苦、性温,具有理气和中,燥湿化痰,利水通便的功效,用于脾胃不和、脘腹胀痛、不思饮食、呕吐哕逆、痰湿阻肺、咳嗽痰多、胸膈满闷、头目眩晕、水肿、小便不利、大便秘结、乳痈疥癣、中鱼蟹毒、酒毒等症;
枳实(炒)性味:苦、寒,具有破气、散痞、泻痰、消积之功效,用于治疗胸腹胀满、胸痹、痞痛、痰癖、水肿、食积、便秘、胃下垂、子宫下垂、脱肛;
川楝子,性味:苦、寒,有小毒,具有舒肝行气止痛、驱虫之功效,用于治疗胸胁、脘腹胀痛、疝痛、虫积腹痛;
沉香,性味:辛苦、温,具有降气温中、暖肾纳气之功效,用于治疗气逆喘息、呕吐呃逆、脘腹胀痛、腰膝虚冷、大肠虚秘、小便气淋、男子精冷;
檀香,性味:辛、性温,具有行气、散寒、止痛之功效,用于治疗胸腹胀痛、霍乱吐泻、噎膈吐食、寒疝腹痛及肿毒;
香附子,性味:味辛、微寒,无毒,具有理气解郁、调经止痛、安胎之功效,用于治疗胁肋胀痛、***胀育、疝气疼痛、***、脘腹痞满疼痛、嗳气吞酸,呕恶、经行腹痛、崩漏带下、胎动不安等症;
玫瑰花,性味:甘、微苦、温,具有理气解郁、和血散瘀之功效,用于治疗肝胃气痛、新久风痹、吐血咯血、***、赤白带下、痢疾、乳痈、肿毒;
九香虫,性味:味咸、性温,具有行气止痛、温肾壮阳之功效,用于治疗肝胃不和或寒郁中焦所致的胸历胁胃脘胀痛,以及坚阳不足之腰痛、阳痿等症;
木香,性味:辛苦、温,具有行气止痛、温中和胃之功效,用于治疗中寒气滞、胸腹胀痛、呕吐、泄泻、下痢里急后重、寒疝;
厚朴, 性味:苦、辛、温,具有燥湿消痰、下气除满之功效,用于治疗湿阻中焦,脘腹胀满,食积气滞,腹胀便秘, 痰饮喘咳;此外,七情郁结,痰气互阻,咽中如有物阻,咽之不下,吐之不出的梅核气证,亦可取本品燥湿消痰,下气宽中之效;
砂仁, 性味:味辛、性温,具有化湿开胃、温脾止泻、理气安胎之功效,用于治疗湿浊中阻、脘痞不饥、脾胃虚寒、呕吐泄泻、妊娠恶阻、胎动不安;
桑叶,性味:味苦、甘、性寒,具有疏散风热、清肺、明目之功效,用于治疗风热感冒、风温初起,发热头痛,汗出恶风,咳嗽胸痛、或肺燥干咳无痰、咽干口渴、风热及肝阳上扰、目赤肿痛;
黄连,性味:苦、寒,具有清热泻火、燥湿、解毒之功效,用于治疗热病邪入心经之高热、烦躁、谵妄或热盛迫血妄行之吐衄、湿热胸痞、泄泻、痢疾、心火亢盛之心烦失眠、胃热呕吐或消谷善饥、肝火目赤肿痛、以及热毒疮疡、疔毒走黄、牙龈肿痛、口舌生疮、聤耳、阴肿、痔血、湿疹、烫伤等症;
大黄,性味:苦、寒,具有泻实热、破积滞、行瘀血之功效,用于治疗实热便秘、食积停滞、腹痛、急性阑尾炎、急性传染性肝炎、血瘀经闭、牙痛、衄血、急性结膜炎、外用治烧烫伤、化脓性皮肤病、痈肿疮疡等症。
本发明药物是基于中医治疗纳呆的原则,从药理作用及其作用机制认为:就纳呆,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述纳呆的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种治疗纳呆的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
苏合香8g、安息香12g、沙参120g、零陵香120g、石菖蒲80g、冰片5g、麦冬(去心)12g、樟脑1.5g、神曲120g、生黄芪200g、当归120g、山药260g、生地黄260g、炒麦芽120g、莱菔子80g、焦槟榔80g、谷芽120g、甘草95g、焦山楂95g、鸡内金(炒120g、陈皮120g、枳实(炒)90g、川楝子70g、沉香45g、檀香22g、香附子95g、玫瑰花230g、九香虫80g、木香80g、厚朴80g、砂仁50g、桑叶95g、黄连45g、大黄170g。
实施例2:
一种治疗纳呆的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
苏合香9g、安息香14g、沙参140g、零陵香140g、石菖蒲90g、冰片5.5g、麦冬(去心)14g、樟脑1.8g、神曲140g、生黄芪230g、当归140g、山药300g、生地黄300g、炒麦芽140g、莱菔子90g、焦槟榔90g、谷芽140g、甘草105g、焦山楂105g、鸡内金(炒) 140g、陈皮140g、枳实(炒)105g、川楝子80g、沉香50g、檀香25g、香附子105g、玫瑰花260g、九香虫90g、木香90g、厚朴90g、砂仁60g、桑叶105g、黄连50g、大黄200g。
实施例3:
一种治疗纳呆的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
苏合香10g、安息香16g、沙参160g、零陵香160g、石菖蒲100g、冰片6g、麦冬(去心)16g、樟脑2g、神曲160g、生黄芪260g、当归160g、山药350g、生地黄360g、炒麦芽160g、莱菔子100g、焦槟榔100g、谷芽160g、甘草120g、焦山楂120g、鸡内金(炒) 160g、陈皮160g、枳实(炒)120g、川楝子90g、沉香60g、檀香30g、香附子120g、玫瑰花300g、九香虫100g、木香100g、厚朴100g、砂仁70g、 桑叶120g、黄连60g、大黄220g。
典型病例
经临床诊断治疗纳呆患者共595例,年龄为45岁以上的300例,只有295例为45岁以下。595例患者中痊愈的586例,显效的的9例,总有效率达100%。
Claims (3)
1.一种治疗纳呆的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
苏合香3~10g、安息香3~16g、沙参100~160g、零陵香100~160g、石菖蒲30~100g、冰片3~6g、麦冬(去心)6~16g、樟脑0.6~2g、神曲100~160g、生黄芪100~260g、当归80~160g、山药150~350g、生地黄100~360g、炒麦芽100~160g、莱菔子50~100g、焦槟榔30~100g、谷芽100~160g、甘草30~120g、焦山楂100~120g、鸡内金(炒)50~160g、陈皮30~160g、枳实(炒)50~120g、川楝子50~90g、沉香30~60g、檀香15~30g、香附子50~120g、玫瑰花30~300g、九香虫30~100g、木香30~100g、厚朴30~100g、砂仁30~70g、 桑叶50~120g、黄连30~60g、大黄50~220g。
2.根据权利要求1所述的治疗纳呆的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
苏合香5~9g、安息香6~14g、沙参115~140g、零陵香115~140g、石菖蒲35~90g、冰片3.5~5.5g、麦冬(去心)10~14g、樟脑0.8~1.8g、神曲115~140g、生黄芪115~230g、当归90~140g、山药170~300g、生地黄115~300g、炒麦芽115~140g、莱菔子60~90g、焦槟榔35~90g、谷芽115~140g、甘草35~105g、焦山楂115~105g、鸡内金(炒)60~140g、陈皮35~140g、枳实(炒)60~105g、川楝子60~80g、沉香35~50g、檀香18~25g、香附子60~105g、玫瑰花35~260g、九香虫35~90g、木香35~90g、厚朴35~90g、砂仁35~60g、 桑叶60~105g、黄连35~50g、大黄60~200g。
3.根据权利要求1至2所述的治疗纳呆的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
苏合香8g、安息香12g、沙参120g、零陵香120g、石菖蒲80g、冰片5g、麦冬(去心)12g、樟脑1.5g、神曲120g、生黄芪200g、当归120g、山药260g、生地黄260g、炒麦芽120g、莱菔子80g、焦槟榔80g、谷芽120g、甘草95g、焦山楂95g、鸡内金(炒120g、陈皮120g、枳实(炒)90g、川楝子70g、沉香45g、檀香22g、香附子95g、玫瑰花230g、九香虫80g、木香80g、厚朴80g、砂仁50g、桑叶95g、黄连45g、大黄170g。
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