CN107050409A - A kind of herbal composite for adjusting intestine of young pigs health and preparation method and application - Google Patents

A kind of herbal composite for adjusting intestine of young pigs health and preparation method and application Download PDF

Info

Publication number
CN107050409A
CN107050409A CN201710139850.3A CN201710139850A CN107050409A CN 107050409 A CN107050409 A CN 107050409A CN 201710139850 A CN201710139850 A CN 201710139850A CN 107050409 A CN107050409 A CN 107050409A
Authority
CN
China
Prior art keywords
intestine
young pigs
atractylodes rhizome
bighead atractylodes
herbal composite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710139850.3A
Other languages
Chinese (zh)
Inventor
乔家运
朱琪
陈龙宾
李海花
王文杰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tianjin Institute of Animal Husbandry and Veterinary Science
Original Assignee
Tianjin Institute of Animal Husbandry and Veterinary Science
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tianjin Institute of Animal Husbandry and Veterinary Science filed Critical Tianjin Institute of Animal Husbandry and Veterinary Science
Priority to CN201710139850.3A priority Critical patent/CN107050409A/en
Publication of CN107050409A publication Critical patent/CN107050409A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998Hordeum (barley)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Fodder In General (AREA)

Abstract

The invention discloses a kind of preparation method for adjusting the healthy herbal composite of intestine of young pigs and application.It is made up of the 10g of rhizoma atractylodis 5, the 8g of the bighead atractylodes rhizome 3, the 12g of rhizoma zingiberis 7, the 5g of dried orange peel 3, the 5g of charred FRUCTUS CRATAEGI 2, the 5g of stir-baked MASSA FERMENTATA MEDICI-NALIS 3, the 5g of melanoidin malt 2.Improving intestine of young pigs form and gut flora the present invention further discloses the healthy herbal composite of regulation intestine of young pigs, the application in terms of improving weaned piglets by promoting intestinal health.As a result show:Two art three is added in baby pig feedstuff celestial scattered, intestine of young pigs form and gut flora can be improved, promote intestinal health effect notable.

Description

A kind of herbal composite for adjusting intestine of young pigs health and preparation method and application
Technical field
The invention belongs to farm animals nutrition technique research field, it is related to a kind of healthy Chinese herbal medicine group of regulation intestine of young pigs Compound and preparation method and application.
Background technology
The health of piglet is largely influenceed by intestinal health, because the enteron aisle of piglet is digestion and absorbs nutrition The important place of material, to safeguarding that piglet is normal, health grow has extremely important effect.Now with pig row Industry develops towards scale, intensive direction, and piglet weans technology in major pig farm extensive uses in advance.General piglet reaches It is to be weaned to 21-28 ages in days, this is all played actively in terms of the utilization rate for growing and improving sow of piglet is promoted Effect.But the development of this stage piglet digestive is perfect not enough, every physiological function is all also unsound, to external world respectively The change performance of kind of factor it is more sensitive, wean can be brought to piglet it is huge stress, and because source of nutrition becomes Change, the intestinal mucosa for being easily caused piglet is destroyed, and causes the nutriment for taking the photograph people to be digested absorption well so that The immunity degradation of piglet, have impact on the health of piglet, growing for weanling pig is obstructed, therefore, carry out the battalion of piglet Support regulation and control work, it is ensured that the health of intestine of young pigs, so as to keep piglet health, the generation of disease is reduced, with highly important Meaning.
The enteron aisle of piglet is the important place of digestion, and Intestinal Morphology change also can be such that intestine of young pigs is made for the absorption of nutrition Into very big injury.Influence of many researchers of China with regard to Bacillus acidi lactici for intestine of young pigs form had certain research, Think that Bacillus acidi lactici can suppress the adhesion of pathogen mucous membrane surface in enteron aisle, reduce the connection of pathogen and enteron aisle, so that Maintain the integrality of intestinal cell.
Bacillus acidi lactici is the normal flora in enteron aisle, and numerous studies all have shown that Bacillus acidi lactici has micro- life in regulation enteron aisle Thing ratio, the advantages of maintaining enteric microorganism stable state, enhancing immunity of organisms.In recent years, the machine of the beneficial body of Bacillus acidi lactici Research processed deepens continuously, as probiotics piglet cultivation on also by increasing concern.Bacillus acidi lactici can produce breast The pH value of the acidic materials such as acid, effectively reduction surrounding environment, can effectively suppress harmful bacteria, if also studies have reported that crossing in son Bacillus acidi lactici is added in the feed of pig can cause the ammonia density in enteron aisle to be eased, and reduce diarrhea rate, also there is research in addition Show that Bacillus acidi lactici can also improve the transformation efficiency of feed, promote piglet growth.
Reasonably use feed addictive.After piglet feeding feed, some can be added in the daily ration of piglet to change It is apt to the feed addictive of intestine of young pigs health to promote the digestion and absorption of piglet, so as to reduce the generation of intestines problem, promotes The health of enteron aisle.Sodium butyrate is added such as in daily ration can promote the propagation of intestinal lactobacillus, so as to reduce Escherichia coli Quantity;When stress reaction occurs for piglet, addition glutamine can reduce the permeability of enteric epithelium, and stable intestines slime layer makes to answer Swash the intestinal mucosa metabolic stability of piglet under state;Various single enzymes or complex enzyme formulation are added in feed, it is probiotics, prebiotic Member, or some medicine class additives can act as the effect of improvement intestinal health.
The development of piglet digestive is perfect not enough, relatively low to nutrient digestion utilization rate.Early stage is being carried out to piglet During wean, huge ablactation stress can be produced, Feed forms, source of nutrition is added and changes and can produce larger shadow to healthy Ring, therefore carry out the intestinal health regulation of piglet and be particularly important.
The content of the invention
By being added in weaning pigs, two art three is celestial to be dissipated for this research, is improved intestine of young pigs form and gut flora, is promoted Enter intestinal health, and then improve the production performance of piglet.
To achieve the above object, the invention discloses following technology contents:
The healthy herbal composite of one kind regulation intestine of young pigs(Two art three is celestial to be dissipated), it is characterised in that it is the original by following weight Material composition:
Rhizoma atractylodis 5-10g, bighead atractylodes rhizome 3-8g, rhizoma zingiberis 7-12g, dried orange peel 3-5g, charred FRUCTUS CRATAEGI 2-5g, stir-baked MASSA FERMENTATA MEDICI-NALIS 3-5g, melanoidin malt 2-5g.
The currently preferred healthy herbal composite of regulation intestine of young pigs(Two art three is celestial to be dissipated), it is characterised in that it be by The raw material composition of following weight:
Rhizoma atractylodis 5g, bighead atractylodes rhizome 3g, rhizoma zingiberis 10g, dried orange peel 3g, charred FRUCTUS CRATAEGI 2g, stir-baked MASSA FERMENTATA MEDICI-NALIS 3g, melanoidin malt 2g.
The present invention further discloses the preparation method of the healthy herbal composite of regulation intestine of young pigs:
(1)The broken sieving of low-temperature submicron powder:Rhizoma atractylodis and bighead atractylodes rhizome cake first crushed 300 mesh sieves with the broken machine of low-temperature submicron powder;Remaining medicine Beater grinder crushing is fixed with small-sized low temperature respectively, 80 mesh sieves are crossed standby.
(2)Mixed components:First will be based on rhizoma atractylodis and the bighead atractylodes rhizome add and be well mixed in mixer, then by rhizoma zingiberis, old Skin is added in mixer and mixed, and is finally gradually added to remaining traditional Chinese medicine powder in mixer by several times, until whole traditional Chinese medicine powders are mixed It is even.All traditional Chinese medicine powders are weighed by prescribed dose electronic scale.
(3)Quality inspection is packed:Finished product should be dried, loose, well mixed, color and luster is consistent, and packaging is using built-in vinyon Bag film, external application plastic-aluminum vacuum valve bag.
The present invention further discloses the healthy herbal composite of regulation intestine of young pigs for adjusting intestine of young pigs form And gut flora, promote the application in terms of intestinal health.Result of the test is shown:Celestial dissipate of two art three is added in Piglet Diets can be with Improve intestine of young pigs health, improve the production performance of piglet.
Rhizoma atractylodis are main ingredient in the formula of the present invention, are aided with the bighead atractylodes rhizome, rhizoma zingiberis, dried orange peel, and Charred Triplet etc., wherein rhizoma atractylodis consumption should More than 15g.
The present invention is according to the various Chinese medicine physicochemical properties and active ingredient in this formula, and the preparation technology to traditional Chinese powder medicine is done System optimization, at utmost to play its drug action.We have mainly investigated following condition in development process:
1st, the broken technology of low-temperature submicron powder
The broken technology of low-temperature submicron powder is carried out to crucial medicinal material rhizoma atractylodis, the bighead atractylodes rhizome in formula, remaining medicinal material low temperature is routinely crushed mixed Close.
2nd, mix:Mixed using equal increments method.
3rd, divided dose:By the contrast with gravimetric method and volumetric method, we determine to use gravimetric method, and this method dosage is accurate, Error is small, easily adjustment.
4th, pack:Packaging is using built-in sealed polyethylene plastic bag, external application plastic-aluminum vacuum valve bag.Preferably prevent from inhaling Wet, caking, changes colour, and decomposes, so as to guaranteed quality and take effect.
The pharmacological action of Chinese medicine used in the present invention is as follows:
Rhizoma atractylodis
Process:Rhizoma atractylodis piece is taken, a few hours are soaked with water in which rice has been washed, is taken out, is put in frying container, heated with moderate heat, when frying to brown, A little clear water is sprayed, then uses slow fire fried dry, taking-up is cooled, and weeds out chip.
Pharmacology:With drying damp and strengthening spleen, wind-dispelling, cold dispelling, the function of improving eyesight.
The bighead atractylodes rhizome:
Process:First pot is heated with moderate heat, wheat bran is sprinkled into, when smoldering, bighead atractylodes rhizome piece is put into, constantly stir-fries, is fried to the bighead atractylodes rhizome in Huang Brown, takes out, weeds out wheat bran, cool.Bighead atractylodes rhizome piece is per 100g wheat bran 10g.
Pharmacology:With strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, antiabortive function.
Rhizoma zingiberis
Process:First net sand is put in frying container, intense fire heating in angle is fried to flexible state, adds in ginger splices or block, constantly turn over It is dynamic, fry to heaving, surface sepia is taken out, weeds out sand, dry in the air cool.
Pharmacology:With warming spleen and stomach for dispelling cold, Back to Yang Tongmai, eliminating dampness dissolving phlegm function.
Hawthorn
Process:Net hawthorn is taken, puts in frying container, is heated with moderate heat, is fried to the burnt brown of appearance, internal coke yellow, taking-up is cooled.
Pharmacology:With promoting digestion and removing indigestion, the stagnant function of stasis of blood row is dissipated.
Divine Comedy
Process:Take raw six songs to put in medicine cookeding pot, heated, constantly stir-fried with slow fire, it is internal slightly yellow to surface coke yellow, there is perfume (or spice) When gas is escaped, take out, cool.
Pharmacology:Function with food digesting stomach fortifying.
Malt
Process:Net malt is taken, according to the method for frying(The stir-fry method for being not added with auxiliary material is referred to as the method for frying.)Fry to burnt brown, cool, weed out ash Bits.
Pharmacology:Relieving dyspepsia.For dyspepsia, abdominal distention.
Dried orange peel
Process:Crude drug is taken, impurity is removed, clear water is sprayed, runs through, chopping is dried in the shade.
Pharmacology:With regulating qi-flowing for strengthening spleen, eliminating dampness and eliminating phlegm function.
More detailed description of the present invention is as follows:
1 materials and methods
1.1 feed addictive prescriptions
Prescription title:Two art three is celestial to be dissipated
Formula:Rhizoma atractylodis 5g, bighead atractylodes rhizome 3g, rhizoma zingiberis 10g, dried orange peel 3g, charred FRUCTUS CRATAEGI 2g, stir-baked MASSA FERMENTATA MEDICI-NALIS 3g, melanoidin malt 2g.
Major function:Eliminating dampness wind-dispelling, strengthening the spleen and stomach, the wide intestines of qi-regulating, change product is led stagnant.For incoordination between the spleen and the stomach, phlegm and retained fluid stagnation, gastral cavity Abdomen feeling of fullness.
Usage and dosage:It is for oral administration, weanling pig consumption 0.5-1g/Kg body weight.Spice is in use, above-mentioned feed addictive is pressed 1-2% addition is used after being mixed with pig starter feed.
Experiment uses corn-soybean meal diet, with reference to NRC(1998)Swine rearing standard preparation pig starter feed.Test daily ration Composition it is as follows:
Corn 60.35, dregs of beans 25, whey powder 5, fish meal 4, soya-bean oil 2.0, calcium monohydrogen phosphate 1.2, stone flour 0.8, salt 0.3, lysine 0.35th, premix 1.
Premix provides VA 12000 IU, VD3 3000 IU, VE 60 IU, VK3 3 ㎎, VB1 3 for every kilogram of diet ㎎, VB2 7.5 ㎎, VB6 4.8 ㎎, VB12 40 ug, the ㎎ of D-VB5 30, the ㎎ of folic acid 1.2, the ㎎ of nicotinic acid 45, biotin 0.22 ㎎, the ㎎ of copper 15, the ㎎ of manganese 50, the ㎎ of zinc 120, the ㎎ of iron 120, the ㎎ of selenium 0.6, the ㎎ of iodine 0.3.
1.2 experimental design
Experiment 28 ages in days of selection(Du × length × big)Weanling pig 80, average weight is 7.36 ± 0.42 kg, by completely random Divide into two processing:Blank control group, diet is without feed addictive;Test group, diet is by 2% addition feed addition Agent.Each 4 repetitions of processing, each repeat 10 piglets, i.e., every group 40 weanling pigs are tested in after the wean of the age in days of piglet 28 Start, 42 ages in days terminate, experimental period is 14 d.
1.3 feeding management
Pig enclosed grazing during experiment, test pig uses identical feeding management and environmental condition, and dry mash feeding is freely adopted Food and drinking-water, are immunized by pig farm normal procedure during experiment, are carried out disinfection and sanitation and hygiene by pig farm feeding management code Deng work.
At the end of testing, four repetitions each handled randomly select 1 piglet and carry out slaughter experiment respectively.Cut open and kill preceding 12 h Fasting, is put to death using the method for jugular vein bloodletting, opens abdominal cavity, and ligation spray door valve, pyloric valve, rectum distal end, sterile to take immediately The contents such as ileum, caecum, are placed in after liquid nitrogen flash freezer, relay frozen in -80 DEG C of refrigerators it is to be analyzed.Take duodenum, jejunum, Ileum etc. is put in 10% neutral formalin fixer, is shaken up, histotomy to be done.
1.4 Testing index and method
1.4.1 enteron aisle structure
The taking-up of the sample after 24 h will be fixed in 10% neutral formalin liquid, it is pruned blocking, distill water washing, gradient wine Essence dehydration, transparent, FFPE, paraffin cooled and solidified, section, paster, bake piece at room temperature, after hematoxylin-eosin (HE) dyeing, Observed under low power lens (5 ×), every sections observation 10-20 root complete, long and straight intestinal villus and corresponding crypts, measurement Height of naps and Crypt depth.
1.4.2 gut flora
In the sterile intestinal contents sample 1g for weighing different parts, the sterile saline for being dissolved in 9 mL, it is sufficiently mixed, then It is serially diluted step by step to 10 for 10 times-7.Selection 10-5-10-7Dilution factor, take 0.1 mL dilutions to be inoculated into corresponding rolling Guan Pei Support and Bacillus acidi lactici culture is carried out in base.Choose 10-2-10-5Dilution factor, take 0.2 mL dilutions in corresponding plating medium The middle counting for carrying out Escherichia coli.
E. coli counts use maconkey agar culture medium:Peptone, 20.0 g/L;Lactose, 10.0g/L;Cholate, 5.0 g/L;Sodium chloride, 5.0 g/L;Dimethyl diaminophenazine chloride, 0.075 g/L;Agar, 12.0 g/L;pH 7.4 ± 0.2.
Bacillus acidi lactici, which is counted, uses Rogosa agar:Tryptone, 10.0 g/L;Yeast extract, 5.0 g/L;Glucose, 20.0 g/L;Tween 80,1.0 mL/L;Potassium dihydrogen phosphate, 6.0 g/L;Ammonium citrate, 2.0 g/L;Sodium acetate, 17.0 g/L; Magnesium sulfate, 0.575g/L;Manganese sulfate, 0.12 g/L;Ferrous sulfate, 0.034 g/L;Agar, 20.0 g/L;pH 5.4 ± 0.2。
1.5 statistical analysis
The indexs such as duodenum, barnyard, the enteron aisle structure of ileum and the gut flora of statistical analysis each group, using single-factor ANOVA(IBM SPSS Statistics 20.0)Variance test is analyzed.Data are represented with " means standard deviation " in text, probability P <Significant difference, probability P are thought when 0.05<Think that difference is extremely notable when 0.01.
2 results and analysis
2.1 enteron aisle structures
As shown in Table 1, during off-test, the Duodenal villi height of test group piglet, duodenal recess depth, 12 fingers Intestines/Crypt depth, Jejunum Crypt depth, ileum height of naps and ileum Crypt depth and control group do not have difference;Test group is young Pig jejunum villi height, jejunum villi height/Crypt depth compared with control group, 13.03%, 21.18%, difference is respectively increased It is extremely notable(P<0.01);Ileum height of naps/Crypt depth of test group piglet improves 13.48%, difference compared with control group It is extremely notable(P<0.01).It was found from result above, diet, which adds celestial dissipate of two art three, to promote intestine of young pigs to develop.
The intestine of young pigs structure of table 1
Note:Colleague's shoulder notes different capitalizations and represents that control group is extremely notable with test group difference(p<0.01).
2.2 gut flora
As shown in Table 2, during off-test, the ileum Escherichia coli level of test group piglet is reduced compared with control group 9.30%, significant difference(P<0.05);The ileum Bacillus acidi lactici level of test group piglet is compared with control group, and raising 5.30% is poor It is different notable(P<0.05);Caecum Escherichia coli level, caecum Bacillus acidi lactici level and the control group of test group piglet do not have difference. It was found from result above, diet, which adds celestial dissipate of two art three, can improve intestine of young pigs Bacterial community.
The intestine of young pigs flora of table 2
Note:Go together different lowercase letter control groups and test group significant difference(p<0.05).
The present invention adds 2% feed addictive in pig starter feed(Two art three is celestial to be dissipated), to feed addictive(Two art three is celestial Dissipate)Safety experiment is carried out, its method is as follows:
1 step:
(1)Material and method:Du × length × big piglet 10 of 28 ages in days is selected, clinical health, development are normal, experimental period 14 My god, poisoning manifestations and death condition are observed in experimental period at any time.
(2)The pig starter feed raw material composition of feeding:
Corn 60.35, dregs of beans 25, whey powder 5, fish meal 4, soya-bean oil 2.0, calcium monohydrogen phosphate 1.2, stone flour 0.8, salt 0.3, lysine 0.35th, premix 1.
Premix provides VA 12000 IU, VD3 3000 IU, VE 60 IU, VK3 3 ㎎, VB1 3 for every kilogram of diet ㎎, VB2 7.5 ㎎, VB6 4.8 ㎎, VB12 40 ug, the ㎎ of D-VB5 30, the ㎎ of folic acid 1.2, the ㎎ of nicotinic acid 45, biotin 0.22 ㎎, the ㎎ of copper 15, the ㎎ of manganese 50, the ㎎ of zinc 120, the ㎎ of iron 120, the ㎎ of selenium 0.6, the ㎎ of iodine 0.3.
In use, celestial dissipate of two art three is added in pig starter feed in 2% ratio, experiment is made and is tested with daily ration.
2 results:The celestial being of two art three is added to pig starter feed to dissipate, continuous feeding 28 days has no obvious intoxicating phenomenon, observation period It is interior without death, each main organs of cut open inspection are shown no obvious abnormalities.
3 conclusions:Two art three of addition 2% in pig starter feed is celestial to dissipate feeding piglet, feeding effect safety.
It is positive that the herbal composite of regulation intestine of young pigs health disclosed by the invention has compared with prior art Effect is:
(1)Rhizoma atractylodis, the bighead atractylodes rhizome in the present invention have good improvement result to intestine of young pigs morphosis and effect are aobvious as main ingredient Write.
(2)Dried orange peel, Divine Comedy, hawthorn, malt compatibility have adjustment effect to intestine of young pigs microorganism species in the present invention, can promote Enter beneficial bacterium propagation, suppress harmful bacteria, so as to be played a positive role to intestinal health.
(3)Chinese herbal medicine in the present invention, safe and efficient, integration of drinking and medicinal herbs.
Embodiment
The present invention is described below by specific embodiment.Unless stated otherwise, technological means used in the present invention It is method known in those skilled in the art.In addition, embodiment is interpreted as illustrative, it is not intended to limit the present invention Scope, the spirit and scope of the invention are limited only by the claims that follow.To those skilled in the art, without departing substantially from this The various changes carried out on the premise of invention spirit and scope to the material component in these embodiments and consumption or change Belong to protection scope of the present invention.Chinese herbal medicine used and reagent of the invention are commercially available.The broken machine of other low-temperature submicron powder is commercially available.
Embodiment 1
The celestial being of two art three is made up of the raw material of following weight:
Rhizoma atractylodis 6g, bighead atractylodes rhizome 5g, rhizoma zingiberis 7g, dried orange peel 5g, charred FRUCTUS CRATAEGI 3g, stir-baked MASSA FERMENTATA MEDICI-NALIS 3g, melanoidin malt 3g.
Embodiment 2
The celestial being of two art three is made up of the raw material of following weight:
Rhizoma atractylodis 5g, bighead atractylodes rhizome 3g, rhizoma zingiberis 10g, dried orange peel 3g, charred FRUCTUS CRATAEGI 2g, stir-baked MASSA FERMENTATA MEDICI-NALIS 3g, melanoidin malt 2g.
Embodiment 3(Embodiment 1-2)
Adjust the preparation method of the healthy herbal composite of intestine of young pigs:
(1)The broken sieving of low-temperature submicron powder:Rhizoma atractylodis and bighead atractylodes rhizome cake first crushed 300 mesh sieves with the broken machine of low-temperature submicron powder;Remaining medicine Beater grinder crushing is fixed with small-sized low temperature respectively, 80 mesh sieves are crossed standby.
(2)Mixed components:First will be based on rhizoma atractylodis and the bighead atractylodes rhizome add and be well mixed in mixer, then by rhizoma zingiberis, old Skin is added in mixer and mixed, and is finally gradually added to remaining traditional Chinese medicine powder in mixer by several times, until whole traditional Chinese medicine powders are mixed It is even.All traditional Chinese medicine powders are weighed by prescribed dose electronic scale.
(3)Quality inspection is packed:Finished product should be dried, loose, well mixed, color and luster is consistent, and packaging is using built-in vinyon Bag film, external application plastic-aluminum vacuum valve bag.

Claims (5)

1. the healthy herbal composite of one kind regulation intestine of young pigs, it is characterised in that it is made up of the raw material of following weight:
Rhizoma atractylodis 5-10g, bighead atractylodes rhizome 3-8g, rhizoma zingiberis 7-12g, dried orange peel 3-5g,
Charred FRUCTUS CRATAEGI 2-5g, stir-baked MASSA FERMENTATA MEDICI-NALIS 3-5g, melanoidin malt 2-5g.
2. the composition described in claim 1, it is characterised in that it is made up of the raw material of following weight:
Rhizoma atractylodis 5g, bighead atractylodes rhizome 3g, rhizoma zingiberis 10g, dried orange peel 3g, charred FRUCTUS CRATAEGI 2g, stir-baked MASSA FERMENTATA MEDICI-NALIS 3g, melanoidin malt 2g.
3. the preparation method of any one of the claim 1-2 additives, it is characterised in that carried out by the steps:
(1)The broken sieving of low-temperature submicron powder:Rhizoma atractylodis and bighead atractylodes rhizome cake first crushed 300 mesh sieves with the broken machine of low-temperature submicron powder;Remaining medicine Beater grinder crushing is fixed with small-sized low temperature respectively, 80 mesh sieves are crossed standby;
(2)Mixed components:First rhizoma atractylodis and the bighead atractylodes rhizome are added based on being well mixed in mixer, then added rhizoma zingiberis, dried orange peel Enter in mixer and mix, be finally gradually added to remaining traditional Chinese medicine powder in mixer by several times, until whole traditional Chinese medicine powders are mixed, institute There is traditional Chinese medicine powder to be weighed by prescribed dose electronic scale;
(3)Quality inspection is packed:Finished product should be dried, loose, well mixed, color and luster is consistent, and packaging is using built-in sealed polyethylene plastic Bag, external application plastic-aluminum vacuum valve bag.
4. the healthy herbal composite of intestine of young pigs is adjusted described in claim 1 is improving intestine of young pigs form and gut flora, Promote the application of chitling road development.
5. application of the healthy herbal composite of intestine of young pigs in terms of weaned piglets are improved is adjusted described in claim 1.
CN201710139850.3A 2017-03-10 2017-03-10 A kind of herbal composite for adjusting intestine of young pigs health and preparation method and application Pending CN107050409A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710139850.3A CN107050409A (en) 2017-03-10 2017-03-10 A kind of herbal composite for adjusting intestine of young pigs health and preparation method and application

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710139850.3A CN107050409A (en) 2017-03-10 2017-03-10 A kind of herbal composite for adjusting intestine of young pigs health and preparation method and application

Publications (1)

Publication Number Publication Date
CN107050409A true CN107050409A (en) 2017-08-18

Family

ID=59622614

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710139850.3A Pending CN107050409A (en) 2017-03-10 2017-03-10 A kind of herbal composite for adjusting intestine of young pigs health and preparation method and application

Country Status (1)

Country Link
CN (1) CN107050409A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107518189A (en) * 2017-09-01 2017-12-29 山西碧云天饲料有限公司 A kind of child care pig starter feed for adding antibacterial peptide and Chinese herbal medicine and preparation method thereof
CN113273649A (en) * 2021-06-30 2021-08-20 北京局气网络技术有限公司 Additive for improving pig intestinal flora structure and preparation method thereof
CN113813345A (en) * 2021-10-12 2021-12-21 吴晓林 Fermented traditional Chinese medicine preparation for improving health vitality of young livestock and preparation method thereof
CN116172965A (en) * 2022-09-19 2023-05-30 沈阳药科大学 Preparation method and application of charred triplet formula particles

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101658250A (en) * 2009-08-26 2010-03-03 王直军 Chinese medicinal feed additive for promoting digestion and strengthening stomach
CN103585599A (en) * 2013-11-06 2014-02-19 青岛农业大学 Veterinary medicine for treating animal digestive tract diseases
CN105125972A (en) * 2015-09-21 2015-12-09 山西省农业科学院畜牧兽医研究所 Chinese herbal preparation for improving intestinal microecology and repairing intestinal mucosa injuries of piglets

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101658250A (en) * 2009-08-26 2010-03-03 王直军 Chinese medicinal feed additive for promoting digestion and strengthening stomach
CN103585599A (en) * 2013-11-06 2014-02-19 青岛农业大学 Veterinary medicine for treating animal digestive tract diseases
CN105125972A (en) * 2015-09-21 2015-12-09 山西省农业科学院畜牧兽医研究所 Chinese herbal preparation for improving intestinal microecology and repairing intestinal mucosa injuries of piglets

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107518189A (en) * 2017-09-01 2017-12-29 山西碧云天饲料有限公司 A kind of child care pig starter feed for adding antibacterial peptide and Chinese herbal medicine and preparation method thereof
CN113273649A (en) * 2021-06-30 2021-08-20 北京局气网络技术有限公司 Additive for improving pig intestinal flora structure and preparation method thereof
CN113813345A (en) * 2021-10-12 2021-12-21 吴晓林 Fermented traditional Chinese medicine preparation for improving health vitality of young livestock and preparation method thereof
CN116172965A (en) * 2022-09-19 2023-05-30 沈阳药科大学 Preparation method and application of charred triplet formula particles

Similar Documents

Publication Publication Date Title
CN102754753B (en) Feed for improving growth performances of broiler chickens and preparation method thereof
CN102835609B (en) Pig feed capable of preventing piglets from diarrhea and traditional Chinese medicine composition
CN102450523B (en) Feed for meat ducks and traditional Chinese medicine additive thereof
CN103355552B (en) Mixed feed for carp in fingerling stage and preparation method thereof
CN103749982B (en) Feed for improving egg yield, traditional Chinese medicine additive and preparation method thereof
CN103583928B (en) Feed used for improving immune functions of grass carp
CN105124230A (en) Taihu sheep feed and production method thereof
CN106819497A (en) A kind of feed for improving piglet anti diar rhea ability and preparation method thereof
CN107050409A (en) A kind of herbal composite for adjusting intestine of young pigs health and preparation method and application
CN107198052A (en) A kind of peacock Chinese medicine fodder and preparation method thereof
CN109221675A (en) A kind of feed additive for weaning piglet and preparation method thereof
CN110037127A (en) A kind of probiotics preparation and preparation method thereof improving infant&#39;s enteron aisle
CN103110861A (en) Granular preparation for preventing infants from getting inflamed and adjusting intestines and stomach and preparation method thereof
CN105249109A (en) Preparation method of composite-probiotics-enriched plant enzymes drink capable of improving gastrointestinal function of child
CN104799317B (en) Sweet potato biscuit and preparation method thereof
CN106614310B (en) A kind of cultural method of zinc-rich sheep
CN105685476A (en) Grouper feed and preparing method thereof
CN106577543A (en) Squab breeding method capable of preventing diseases
CN105146134A (en) Green and safe pork type pig feed
CN105941878A (en) Sheep feed curing enteritis and diarrhea
CN105533450A (en) Nutritional health-care rice flour and preparation method thereof
CN103461756B (en) Mixed grain rice total nutrient formula food for patient with cancer
CN107712414A (en) A kind of chicken feed for improving resistance
CN106260658A (en) One boar anti-heat stress Chinese herbal medicine feed additive
CN106107121A (en) A kind of composite feed additive preventing and treating sow puerperal hypogalactia and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20170818