CN107007256A - Photoacoustic imaging fixture and its opto-acoustic imaging devices of application - Google Patents

Photoacoustic imaging fixture and its opto-acoustic imaging devices of application Download PDF

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Publication number
CN107007256A
CN107007256A CN201710116558.XA CN201710116558A CN107007256A CN 107007256 A CN107007256 A CN 107007256A CN 201710116558 A CN201710116558 A CN 201710116558A CN 107007256 A CN107007256 A CN 107007256A
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China
Prior art keywords
accommodating chamber
speculum
waterproof case
photoacoustic imaging
photon
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CN201710116558.XA
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CN107007256B (en
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宋亮
李牧聪
刘成波
邢沐悦
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Shenzhen Institute of Advanced Technology of CAS
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Shenzhen Institute of Advanced Technology of CAS
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Priority to CN201710116558.XA priority Critical patent/CN107007256B/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0093Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
    • A61B5/0095Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements

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  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Acoustics & Sound (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
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Abstract

Embodiment of the present invention discloses a kind of photoacoustic imaging fixture and its opto-acoustic imaging devices of application, belongs to the technical scheme in photoacoustic imaging field, including shell, photon-phonon coupling mechanism and the first waterproof case;Shell includes the housing of two relative splicings, each housing is equipped with the first cavity and the second cavity, two the first cavitys are surrounded by the first accommodating chamber, two the second cavitys are surrounded by the second accommodating chamber, first accommodating chamber is arranged side by side with the second accommodating chamber, and the first end of the first accommodating chamber and the second accommodating chamber with shell is turned on;Photon-phonon coupling mechanism couples with the first end of shell, and photon-phonon coupling mechanism is simultaneously positioned opposite with the first accommodating chamber, the second accommodating chamber;First waterproof case is at the abutting of two housings, and the first waterproof case is used for realizing anti-water segregation between the first accommodating chamber and the second accommodating chamber;This scheme can prevent the water in the first accommodating chamber from leaking out in the second accommodating chamber, so as to avoid influenceing the quality of hot spot, important leverage is provided for the quality of photoacoustic imaging.

Description

Photoacoustic imaging fixture and its opto-acoustic imaging devices of application
Technical field
The present invention relates to the technical scheme in photoacoustic imaging field, the light of more particularly to a kind of photoacoustic imaging fixture and its application Acoustic imaging apparatus.
Background technology
Photoacoustic imaging technology, because it has optical imagery high-contrast and the high-resolution advantage of ultrasonic imaging concurrently, has been subjected to To extensive concern, develop particularly rapid.The mechanism of its high-contrast, be the biological tissue of different constituents has not to light With the absorption of degree.Based on this mechanism, organism chemical constituent and physiological function etc. can be obtained by photoacoustic imaging technology and believed Breath, complements each other with the organizational information acquired in ultrasonic imaging technique.A variety of different types of photoacoustic imaging devices are It is developed, is applied to multiple medical domains, such as infantile tumour detection, the detection of intravascular vulnerable plaque, pin puncture is drawn Sentinel lymph node biopsy in breast cancer led etc..In the last few years, seminar utilizes existing clinical medical supersonic imaging apparatus And its hand-held probe carries out building for photoacoustic imaging, the advantage of this kind of technology is that clinical ultrasound probe can be made full use of just In the characteristic of operation, the optoacoustic detection of body different parts and depth is carried out.In addition, on this basis, the original ultrasound of system Imaging can also be retained, both modalities which can Auto-matching overlap, formed optoacoustic/ultrasound bimodal imaging system, more It is easy to be received by clinician.It there is now various ways and can realize and exciting light is sent to destination organization position, including light field Illumination and dark-ground illumination, are required for realizing consolidating for optical component and ultrasonic probe using the fixture of different shape and function It is set for using.Bright field illumination refers to that, on detecting objects surface, exciting light hot spot is overlapped with supersonic sounding, and during dark-ground illumination, Both are misaligned.The difficult point of mechanical clamp design is essentially consisted in:First will not dramatically increase the feelings of ultrasonic probe size Under condition, the transmission of light is efficiently carried out, it is therefore desirable to enough succinct of the mechanical clamp;Second, it is necessary to retain ultrasonic probe with The high impedance matching properties of tissue, while, it is necessary to so that light path is not contaminated in bright field illumination, it is therefore desirable to probe machinery folder With preferable sealing;3rd, it is necessary to reduce cost of manufacture, and retain the flexibility of its design variation as far as possible.
In the photoacoustic imaging system for being currently based on ultrasonic hand-held linear transducer array, its optoacoustic/ultrasonic double-mode state probe gripper Design mainly have two kinds:
The first be exciting light from light source outgoing, by being divided into two similar circular light spots after fibre bundle.Mechanical clamp Fibre bundle exit end and ultrasonic probe are integrated so that irradiation hot spot is located at ultrasonic probe array element both sides, the convergent point of light harmony Result from organization internal.In such a design, mechanical clamp needs fixed ultrasonic probe simultaneously and its fibre bundle of both sides certain Relative angle, its size-constrained large scale in fibre bundle and this relative angle, be generally difficult to do is compact succinct, So that the operation of doctor is inconvenient.On the other hand, because the light output end of light shafts is not by any waterproofing protection, ultrasound Glue or water easily cause the pollution of fiber end face after sticking together, reduce its service life, and destroy original preferable hot spot shape Shape.
Second of design is by designing L-type mechanical clamp, light path being coupled with ultrasonic probe.Such a jig Design is used The mode of bright field illumination, can preferably couple incident light and ultrasonic probe.Fixture is always divided into three major parts.Its left side the A part is primarily used to mounted lens group, and rightward second portion is used for fixing ultrasonic probe, and Part III is used for carrying out light The coupling of sound and ultrasonic part inside it, it is necessary to install the prism of the anti-sound of printing opacity.Additionally due to ultrasound needs and tissue Coupled, it is necessary to fill up water in Part III.Wherein second and Part III in order to easy for installation and be divided into two sub-portions Part, two parts are connected by screw.Its major defect is:First, probe gripper design is complicated, and size is than larger, no Beneficial to clinic conversion;Second, the water for being filled in Part III easily flows into light path part, pollution light path and optical element, shadow Ring optical quality;3rd, when entering units installation with the fixture, ultrasonic probe is that side is put, and this just puts probe to being used to use Doctor for, it is and inconvenient.
In summary, two ways can not ensure optical quality, have a strong impact on the effect of photoacoustic imaging.
The content of the invention
, can not to solve prior art it is an object of the invention to provide a kind of photoacoustic imaging fixture and opto-acoustic imaging devices The problem of ensureing optical quality.
In order to solve the above-mentioned technical problem, the invention provides a kind of photoacoustic imaging fixture, including shell, photon-phonon coupling machine Structure and the first waterproof case;The shell includes the housings of two relative splicings, and each housing is equipped with the first cavity and the Two cavitys, two first cavitys are surrounded by the first accommodating chamber, and two second cavitys are surrounded by the second accommodating chamber, described First accommodating chamber is arranged side by side with second accommodating chamber, first accommodating chamber and second accommodating chamber with the shell First end conducting;The photon-phonon coupling mechanism couples with the first end of the shell, the photon-phonon coupling mechanism simultaneously with institute State the first accommodating chamber, second accommodating chamber positioned opposite;First waterproof case is at the abutting of two housings, institute Stating the first waterproof case is used for realizing anti-water segregation between first accommodating chamber and second accommodating chamber.
Wherein, the photon-phonon coupling mechanism includes the first speculum and the second speculum;First speculum with it is described First accommodating chamber is positioned opposite, and the reflecting surface of first speculum is towards outside first accommodating chamber;Second speculum It is positioned opposite with second accommodating chamber, the reflecting surface of second speculum reflecting surface simultaneously with first speculum, Second accommodating chamber is relative.
Wherein, the reflecting surface of first speculum is parallel with the reflecting surface of second speculum relative.
Wherein, the reflecting surface of first speculum and the central axial angle of first accommodating chamber are 45 °, described the The reflecting surface of two-mirror and the central axial angle of second accommodating chamber are 45 °.
Wherein, the photon-phonon coupling mechanism also include lucite, the lucite simultaneously with first accommodating chamber, Second accommodating chamber is positioned opposite, and first speculum and second speculum are inside the lucite.
Wherein, plano-convex post lens and Plano concave cylindr lens are provided with second accommodating chamber, the plano-convex post lens include phase A convex surface and a plane to arrangement, the Plano concave cylindr lens include a concave surface positioned opposite and a plane, the plane-concave column Lens are placed between the plano-convex post lens and second speculum, the plane of the Plano concave cylindr lens and the described second reflection The reflecting surface of mirror is positioned opposite, and the concave surface of the Plano concave cylindr lens and the plane of the plano-convex post lens are positioned opposite.
Wherein, the photoacoustic imaging fixture also includes the second waterproof case, and second waterproof case is located at the shell first Between the end face at end and the photon-phonon coupling mechanism, second waterproof case possesses two cyclic structures, a ring-type knot Structure surrounds the port arrangements of first accommodating chamber, and another described cyclic structure surrounds the port cloth of second accommodating chamber Put.
Wherein, one end of first waterproof case extends to the first end of the shell, and with the second waterproof case phase Connect, the first waterproof case second end end face of the other end away from the shell;The photoacoustic imaging fixture also includes three proofings Water part, the 3rd waterproof case is in first accommodating chamber, and the 3rd waterproof case is located at the two ends of the first waterproof case Between, the 3rd waterproof case is arranged as ring-type around the described first receiving cavity wall, and the 3rd waterproof case is used for described First accommodating chamber loads after ultrasonic probe, and liquid storage cylinder is separated to form in first accommodating chamber.
Wherein, the end of at least one housing offers water injection hole, and the water injection hole is turned on the liquid storage cylinder, institute The part for stating waterproof case is blocked between the water injection hole and the liquid storage cylinder.
A kind of opto-acoustic imaging devices, including ultrasonic probe, optical fiber and above-mentioned photoacoustic imaging fixture, the ultrasonic probe are set In in first accommodating chamber, the optical fiber is in second accommodating chamber, the transmitting of the ultrasonic probe and the optical fiber End is towards the photon-phonon coupling mechanism.
Beneficial effects of the present invention are as follows:
In use, it is necessary to which ultrasonic probe is positioned in the first accommodating chamber, optical fiber is positioned over the second accommodating chamber It is interior, and the water filling in the first accommodating chamber, but because first waterproof case is at the abutting of two housings, the waterproof Part is used for realizing anti-water segregation between first accommodating chamber and second accommodating chamber, thus the water in the first accommodating chamber without Method is leaked out in the second accommodating chamber, so as to avoid influenceing the quality of hot spot, important leverage is provided for the quality of photoacoustic imaging.
Brief description of the drawings
In order to illustrate more clearly of technical scheme, the required accompanying drawing used in embodiment will be made below Simply introduce, it should be apparent that, drawings in the following description are only some embodiments of the present invention, general for this area For logical technical staff, on the premise of not paying creative work, other accompanying drawings can also be obtained according to these accompanying drawings.
Fig. 1 is the structural representation that the preferred embodiment for the present invention is provided;
Fig. 2 is the assembling of the first waterproof case, the second waterproof case and the 3rd waterproof case that the preferred embodiment for the present invention is provided Relation schematic diagram;
Fig. 3 is the positioning slot structure schematic diagram that the preferred embodiment for the present invention is provided.
Reference is as follows:
1st, ultrasonic probe;
2nd, optical fiber;
3rd, photon-phonon coupling mechanism;31st, the first speculum;32nd, the second speculum;33rd, lucite;
41st, the first waterproof case;42nd, the second waterproof case;43rd, the 3rd waterproof case;
5th, plano-convex post lens;
6th, Plano concave cylindr lens;
7th, housing;
8th, liquid storage cylinder;
9th, water injection hole;
10th, locating slot;101st, raised line.
Embodiment
Below in conjunction with the accompanying drawing in embodiment of the present invention, the technical scheme in embodiment of the present invention is carried out clear Chu, it is fully described by.
It was found from Fig. 1 to 3, the photoacoustic imaging fixture described in embodiment of the present invention, including shell, photon-phonon coupling mechanism 3 With the first waterproof case 41;The shell includes the housings 7 of two relative splicings, each housing 7 be equipped with the first cavity and Second cavity, two first cavitys are surrounded by the first accommodating chamber, and two second cavitys are surrounded by the second accommodating chamber, institute The first accommodating chamber is stated to be arranged side by side with second accommodating chamber, first accommodating chamber and second accommodating chamber with it is described outer The first end conducting of shell;The photon-phonon coupling mechanism 3 couples with the first end of the shell, and the photon-phonon coupling mechanism 3 is simultaneously It is positioned opposite with first accommodating chamber, second accommodating chamber;First waterproof case 41 is supported located at two housings 7 Place is met, first waterproof case 41 is used for realizing anti-water segregation between first accommodating chamber and second accommodating chamber.
Reference is shown with Fig. 1, housing 7 includes left side edge, center edge portion (not shown) and right side edge, housing It is the first cavity between 7 left side edge and center edge portion, is the second cavity between the center edge portion of housing 7 and right side edge, and First waterproof case 41 will be located at the surface of left side edge, center edge portion and the right side edge of housing 7 simultaneously, when two housings 7 are spelled It is connected in after one, just the first waterproof case 41 can be gripped, and the first accommodating chamber is formed in the left side of shell, in shell Right side formed the second accommodating chamber, wherein, using process approximately as:
1st, ultrasonic probe 1 is positioned in the first accommodating chamber, optical fiber 2 is positioned in the second accommodating chamber, and keep ultrasound The transmitting terminal of probe 1 and optical fiber 2 is towards photon-phonon coupling mechanism 3;
2nd, the water filling in the first accommodating chamber so that water level can flood the transmitting terminal of lid ultrasonic probe 1;
3rd, ultrasonic probe 1 sends sound wave, and transmitting terminal of the light source through optical fiber 2 is projected, and both converge in photon-phonon coupling mechanism 3 Poly-, coupling, and be incident upon in the tissue for needing to carry out photoacoustic imaging.
Due to realizing anti-water segregation between 41 pair of first accommodating chamber of the first waterproof case and the second accommodating chamber, so first holds The water of intracavitary received can not be leaked out in the second accommodating chamber, so as to avoid influenceing the quality of hot spot, provided for the quality of photoacoustic imaging Important leverage;In addition, from fig. 1, it can be seen that in use, the water in the first accommodating chamber only needs to flood the hair of ultrasonic probe 1 Penetrate end just can, so the length of the first waterproof case 41 can be shortened suitably, the two ends without extending to shell simultaneously.
A kind of improve of photoacoustic imaging fixture described in embodiment of the present invention can be as shown in figure 1, the photon-phonon coupling mechanism 3 Including the first speculum 31 and the second speculum 32;First speculum 31 and first accommodating chamber are positioned opposite, described The reflecting surface of first speculum 31 is towards outside first accommodating chamber;Second speculum 32 is relative with second accommodating chamber Arrangement, the reflecting surface of second speculum 32 reflecting surface simultaneously with first speculum 31, the second accommodating chamber phase It is right.
Its course of work approximately as:
1st, ultrasonic probe 1 sends sound wave, and transmitting terminal of the light through optical fiber 2 of light source is projected;
2nd, outgoing route of the sound wave along ultrasonic probe 1 is sent;
3rd, the light of light source is incident upon on the reflecting surface of the second speculum 32, and reflexes to the reflecting surface of the first speculum 31 On, then projected along the bearing of trend of the outgoing route of ultrasonic probe 1, and coupled with sound wave generation.
By the collective effect of the first speculum 31 and the second speculum 32 so that the injection path of light source finally and ultrasound The outgoing route of probe 1 is consistent, thus sound wave will be produced with light source meet, it is overlapping, the coupling of sound wave and light source is realized with this.
A kind of improve of photoacoustic imaging fixture described in embodiment of the present invention can be as shown in figure 1, first speculum 31 Reflecting surface it is parallel with the reflecting surface of second speculum 32 relative.
Using direction shown in Fig. 1 as reference, it is assumed that now transmitting terminal of the light source through optical fiber 2 is projected, its project direction perpendicular to Horizontal direction, it can be seen from incidence angle is equal to the principle of angle of reflection, in the reflecting surface and the second speculum 32 of the first speculum 31 Reflecting surface it is parallel it is relative in the case of, light source can be kept to be projected perpendicular to the angle of horizontal direction, i.e., in progress optoacoustic During imaging, opto-acoustic imaging devices, which can keep just putting angle, to be detected, and is that the operation of doctor brings great convenience.
It may be noted that the angle of inclination of the first speculum 31 and the second speculum 32 can influence the reflection direction of light source, it is Ensure that the first speculum 31 can receive light source at the second speculum 32, both distances in vertical direction need to be adjusted, i.e., The angle of inclination of first speculum 31 and the second speculum 32 will influence the thickness of photon-phonon coupling mechanism 3.
A kind of improve of photoacoustic imaging fixture described in embodiment of the present invention can be as shown in figure 1, first speculum 31 Reflecting surface and the central axial angle of first accommodating chamber be 45 °, the reflecting surface of second speculum 32 and described the The central axial angle of two accommodating chambers is 45 °.
Using direction shown in Fig. 1 as reference, it is assumed that now transmitting terminal of the light source through optical fiber 2 is projected, its project direction perpendicular to Horizontal direction, it can be seen from incidence angle is equal to the principle of angle of reflection, in the reflecting surface and the second speculum 32 of the first speculum 31 Reflecting surface keep 45 ° be in tilted layout in the case of, light source will reflex to the first reflection with horizontal direction from the second speculum 32 Mirror 31 so that the first speculum 31 and the second speculum 32 are arranged in same level, reduces the occupancy of photon-phonon coupling mechanism 3 Space, valuable help is provided to reduce equipment volume.
A kind of improve of photoacoustic imaging fixture described in embodiment of the present invention can be as shown in figure 1, the photon-phonon coupling mechanism 3 Also include lucite 33, the lucite 33 while, institute positioned opposite with first accommodating chamber, second accommodating chamber The first speculum 31 and second speculum 32 are stated inside the lucite 33.
The area of lucite 33 could be arranged to, and with the port of shell relative cloth consistent with the area of outer cover port Put, to ensure that the sound wave sent of ultrasonic probe 1 and the light source projected from optical fiber 2 can be projected by lucite 33;Separately Outside, because lucite 33 is most excellent macromolecule transparent material at present, light transmittance reaches 92%, than the light transmittance of glass Height, can reduce loss when light source is projected;Furthermore, lucite 33 has good comprehensive mechanical property, can be to its inside The first speculum 31 and the second speculum 32 protected, for improve opto-acoustic imaging devices service life provide important side Help.
A kind of improve of photoacoustic imaging fixture described in embodiment of the present invention can be as shown in figure 1, in second accommodating chamber Provided with plano-convex post lens 5 and Plano concave cylindr lens 6, the plano-convex post lens 5 include a convex surface positioned opposite and a plane, described Plano concave cylindr lens 6 include a concave surface positioned opposite and a plane, the Plano concave cylindr lens 6 be placed in the plano-convex post lens 5 with Between second speculum 32, the plane of the Plano concave cylindr lens 6 and the reflecting surface of second speculum 32 are positioned opposite, The concave surface of the Plano concave cylindr lens 6 and the plane of the plano-convex post lens 5 are positioned opposite.
When light source is projected from the transmitting terminal of optical fiber 2, light source can sequentially pass through the convex surfaces of plano-convex post lens 5 and plane, flat The concave surface of concave cylindrical lenses 6 and plane, are matched the circular light broadening that optical fiber 2 is launched into the search coverage of ultrasonic probe 1 with this Rectangular elongate hot spot, improve photoacoustic imaging quality.
A kind of improve of photoacoustic imaging fixture described in embodiment of the present invention can be such as Fig. 1 and 2, and the photoacoustic imaging fixture is also Including the second waterproof case 42, end face and the photon-phonon coupling mechanism 3 of second waterproof case 42 located at the shell first end Between, second waterproof case 42 possesses two cyclic structures, and a cyclic structure surrounds the end of first accommodating chamber Mouth arrangement, another described cyclic structure surrounds the port arrangements of second accommodating chamber.
Refer to the attached drawing 1 and 2 understands that in use, the left and right sides of the second waterproof case 42 is respectively provided with a ring-type knot Structure, the cyclic structure for being placed in left side will be around the port perimeter arrangement of the first accommodating chamber, and the cyclic structure for being placed in right side will be around The port perimeter arrangement of second accommodating chamber, i.e., further strengthen the first accommodating chamber and the second accommodating chamber by the second waterproof case 42 Anti- water segregation, so the water in the first accommodating chamber can not leak out to the second receiving through the junction of shell and photon-phonon coupling mechanism 3 Chamber, so as to avoid influenceing the quality of hot spot, important leverage is provided for the quality of photoacoustic imaging.
Photoacoustic imaging fixture described in embodiment of the present invention it is a kind of improve can such as Fig. 1 and 2, first waterproof case 41 One end extends to the first end of the shell, and connects with second waterproof case 42, the first waterproof case 41 the other end it is remote From the second end end face of the shell;The photoacoustic imaging fixture also includes the 3rd waterproof case 43, and the 3rd waterproof case 43 is set In in first accommodating chamber, and the 3rd waterproof case 43 is between the two ends of the first waterproof case 41, the 3rd waterproof Part 43 is arranged as ring-type around the described first receiving cavity wall, and the 3rd waterproof case 43 is used to load in first accommodating chamber After ultrasonic probe 1, liquid storage cylinder 8 is separated to form in first accommodating chamber.
From fig. 1, it can be seen that in use, the water in the first accommodating chamber only need to flood the transmitting terminal of ultrasonic probe 1 just can, So the length of the first waterproof case 41 can be shortened suitably, the two ends without extending to shell simultaneously;In addition, being accommodated when first Intracavitary loads after ultrasonic probe 1, and the 3rd waterproof case 43 for being arranged as ring-type fits the outer wall with ultrasonic probe 1, with this Liquid storage cylinder 8 is separated to form in one accommodating chamber, from fig. 1, it can be seen that because the volume of liquid storage cylinder 8 is much smaller than the volume of the first accommodating chamber, Less water, which need to only be injected, just can ensure to flood the transmitting terminal of lid ultrasonic probe 1, and the accommodating chamber waterproof of liquid storage cylinder 8 and first every From also avoiding liquid storage cylinder 8 from seeping water to the first accommodating chamber, kept for the moment of ultrasonic probe 1 be in the state of lid of being flooded, be optoacoustic The quality of imaging, which is provided, to be ensured.
In addition, the first waterproof case 41 shown in Fig. 1 is arc, the first waterproof case 41 shown in Fig. 2 is bar shaped, specifically because It can be made up, the first waterproof case 41 can be bent in installation process of soft materials such as rubber of the first waterproof case 41, Being matched with this needs progress to be installed as position, similarly, and the second waterproof case 42 and the 3rd waterproof case 43 are also such.
Further, can in order to strengthen the fixation to the first waterproof case 41, the second waterproof case 42 and the 3rd waterproof case 43 With the corresponding position of housing 7 set locating slot 10, by corresponding waterproof case be embedded in locating slot 10 in just can, as shown in figure 3, also Raised line 101, bearing of trend arrangement of the raised line 101 along locating slot 10, it is assumed that needs pair can be set in the bottom land of locating slot 10 First waterproof case 41 is fixed, after two housings 7 and photon-phonon coupling mechanism 3 are assembled into one, and raised line 101 will embedded first In waterproof case 41, the position of water-proof strip can be fixed by extruding force, and increase the first waterproof case 41 and the journey of fitting between housing 7 Degree, it is to avoid produce seepage through the first waterproof case 41, similarly, the second waterproof case 42 and the 3rd waterproof case 43 are also such.
A kind of improve of photoacoustic imaging fixture described in embodiment of the present invention can be as shown in figure 1, at least one described housing 7 End offer water injection hole 9, the water injection hole 9 is turned on the liquid storage cylinder 8, and a part for the waterproof case 4 is blocked in institute State between water injection hole 9 and the liquid storage cylinder 8.
In use, water filling can be carried out to liquid storage cylinder 8 by water injection hole 9, for example passes through water injection hole using needle tubing 9th, waterproof case 4 so that needle tubing is inserted into liquid storage cylinder 8, the then water filling in liquid storage cylinder 8 after water filling is finished, is taken out needle tubing, prevented Water part 4 is just blocked to water injection hole 9 automatically because of elastic deformation, so as to avoid water injection hole 9 from infiltration phenomenon occur;Wherein it is possible to As needed, select different flexible glues, cushion as waterproof case 4, clog various gaps as long as can be abutted by elasticity, it is to avoid go out Now infiltration phenomenon just may be used.
From fig. 1, it can be seen that the opto-acoustic imaging devices described in embodiment of the present invention, including ultrasonic probe 1, optical fiber 2 and above-mentioned Photoacoustic imaging fixture, the ultrasonic probe 1 is in first accommodating chamber, and the optical fiber 2 is located at second accommodating chamber Interior, the transmitting terminal of the ultrasonic probe 1 and the optical fiber 2 is towards the photon-phonon coupling mechanism 3.
Specifically, it is also possible that the outgoing route of the outgoing route of ultrasonic probe 1 and optical fiber 2 is parallel to each other, now The both sides of one accommodating chamber could be arranged to the side wall of ultrasonic probe 1, and the both sides of the second accommodating chamber could be arranged to light The side wall of fibre 2, the i.e. horizontal space-consuming of the first accommodating chamber is consistent with the width of ultrasonic probe 1, and the transverse direction of the second accommodating chamber is accounted for It is consistent with the width of optical fiber 2 with space so that the volume of shell can tend to minimize, provided for diminution equipment volume important Help.
Described above is the preferred embodiment of the present invention, it is noted that for those skilled in the art For, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications are also considered as Protection scope of the present invention.

Claims (10)

1. a kind of photoacoustic imaging fixture, it is characterised in that
Including shell, photon-phonon coupling mechanism and the first waterproof case;
The shell includes the housing of two relative splicings, and each housing is equipped with the first cavity and the second cavity, two First cavity is surrounded by the first accommodating chamber, and two second cavitys are surrounded by the second accommodating chamber, first accommodating chamber It is arranged side by side with second accommodating chamber, the first end of first accommodating chamber and second accommodating chamber with the shell is led It is logical;
The photon-phonon coupling mechanism couples with the first end of the shell, and the photon-phonon coupling mechanism is accommodated with described first simultaneously Chamber, second accommodating chamber are positioned opposite;
First waterproof case is at the abutting of two housings, and first waterproof case is used for first accommodating chamber Anti- water segregation is realized between second accommodating chamber.
2. photoacoustic imaging fixture according to claim 1, it is characterised in that
The photon-phonon coupling mechanism includes the first speculum and the second speculum;
First speculum and first accommodating chamber are positioned opposite, and the reflecting surface of first speculum is towards described first Outside accommodating chamber;
Second speculum and second accommodating chamber are positioned opposite, and the reflecting surface of second speculum is simultaneously with described the The reflecting surface of one speculum, second accommodating chamber are relative.
3. photoacoustic imaging fixture according to claim 2, it is characterised in that the reflecting surface of first speculum with it is described The reflecting surface of second speculum is parallel relative.
4. photoacoustic imaging fixture according to claim 3, it is characterised in that the reflecting surface of first speculum with it is described The central axial angle of first accommodating chamber is 45 °, and the reflecting surface of second speculum and second accommodating chamber are central axial Angle be 45 °.
5. photoacoustic imaging fixture according to claim 2, it is characterised in that the photon-phonon coupling mechanism also includes organic glass Glass, the lucite are while, first speculum and institute positioned opposite with first accommodating chamber, second accommodating chamber The second speculum is stated inside the lucite.
6. photoacoustic imaging fixture according to claim 2, it is characterised in that saturating provided with plano-convex post in second accommodating chamber Mirror and Plano concave cylindr lens, the plano-convex post lens include a convex surface positioned opposite and a plane, and the Plano concave cylindr lens include A concave surface positioned opposite and a plane, the Plano concave cylindr lens be placed in the plano-convex post lens and second speculum it Between, the plane of the Plano concave cylindr lens and the reflecting surface of second speculum are positioned opposite, the concave surface of the Plano concave cylindr lens Plane with the plano-convex post lens is positioned opposite.
7. photoacoustic imaging fixture according to claim 1, it is characterised in that the photoacoustic imaging fixture, which also includes second, to be prevented Water part, second waterproof case is between the end face and the photon-phonon coupling mechanism of the shell first end, and described second prevents Water part possesses two cyclic structures, and a cyclic structure surrounds the port arrangements of first accommodating chamber, described in another Cyclic structure surrounds the port arrangements of second accommodating chamber.
8. photoacoustic imaging fixture according to claim 7, it is characterised in that
One end of first waterproof case extends to the first end of the shell, and connects with second waterproof case, institute first Second end end face of the other end of waterproof case away from the shell;
The photoacoustic imaging fixture also includes the 3rd waterproof case, and the 3rd waterproof case is in first accommodating chamber, and institute The 3rd waterproof case is stated between the two ends of the first waterproof case, the 3rd waterproof case accommodates cavity wall arrangement around described first For ring-type, the 3rd waterproof case is used for after first accommodating chamber loads ultrasonic probe, divides in first accommodating chamber Every formation liquid storage cylinder.
9. photoacoustic imaging fixture according to claim 8, it is characterised in that the end of at least one housing is offered Water injection hole, the water injection hole is turned on the liquid storage cylinder, and a part for the waterproof case is blocked in the water injection hole and the storage Between sap cavity.
10. a kind of opto-acoustic imaging devices, it is characterised in that including described in ultrasonic probe, optical fiber and any one of claim 1 to 9 Photoacoustic imaging fixture, the ultrasonic probe in first accommodating chamber, the optical fiber in second accommodating chamber, The transmitting terminal of the ultrasonic probe and the optical fiber is towards the photon-phonon coupling mechanism.
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