CN106942505B - A kind of feed addictive and its application method improving Pili in Fetus of Haired Rabbit production performance - Google Patents
A kind of feed addictive and its application method improving Pili in Fetus of Haired Rabbit production performance Download PDFInfo
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- 238000004519 manufacturing process Methods 0.000 title claims abstract description 30
- 238000000034 method Methods 0.000 title abstract description 11
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims abstract description 52
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 36
- 239000000843 powder Substances 0.000 claims abstract description 33
- 239000011669 selenium Substances 0.000 claims abstract description 26
- 229960003080 taurine Drugs 0.000 claims abstract description 26
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims abstract description 24
- 229910052711 selenium Inorganic materials 0.000 claims abstract description 24
- 235000006886 Zingiber officinale Nutrition 0.000 claims abstract description 23
- 235000008397 ginger Nutrition 0.000 claims abstract description 23
- 244000063299 Bacillus subtilis Species 0.000 claims abstract description 16
- 235000014469 Bacillus subtilis Nutrition 0.000 claims abstract description 16
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims abstract description 12
- 229930182817 methionine Natural products 0.000 claims abstract description 12
- 239000007787 solid Substances 0.000 claims description 37
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims description 34
- 241000234314 Zingiber Species 0.000 claims description 22
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Landscapes
- Fodder In General (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a kind of feed addictives and its application method for improving Pili in Fetus of Haired Rabbit production performance.The feed addictive is using yeast aspergillus culture D3 as diluent; compound bacillus subtilis, yeast selenium, methionine, taurine and ginger powder; each raw material collective effect; it can promote the lipid-metabolism of Pili in Fetus of Haired Rabbit; improve immunity and resistance to oxidation; the growth for promoting Pili in Fetus of Haired Rabbit, can especially increase the follicle population of long haired rabbit skin skin tissue, improve the wool production of Pili in Fetus of Haired Rabbit.Antibiotic when basal diet is prepared in the 5 ‰ alternative daily rations of the feed addictive of addition, to improve Pili in Fetus of Haired Rabbit production performance and the general level of the health.
Description
Technical field
The present invention relates to a kind of feed addictives and its application method for improving Pili in Fetus of Haired Rabbit production performance, belong to feed technology
Field.
Background technique
The Pili in Fetus of Haired Rabbit rabbit hair has many advantages, such as warming, slim and graceful, soft, good hygroscopicity, is natural grade textiles raw material.Make
It is hair with economic animal, the Pili in Fetus of Haired Rabbit rabbit hair is expected same wool in the effect of textile industry and has half share.With people's living standard
The improvement with rabbit hair textile technology is improved, it is increasing to the demand of the rabbit hair.But current rabbit hair yield is lower, seriously undermines
The market competitiveness of the Pili in Fetus of Haired Rabbit rabbit hair constrains the development of Pili in Fetus of Haired Rabbit industry.By to hair follicle molecular regulation, environment and nutrition tune
The research of control can find out the method for improving rabbit hair yield.But other than sulfur-containing amino acid, other improvement are not found at present
The Pili in Fetus of Haired Rabbit feed additive special of rabbit hair growth.
European Union completely forbids food animal and uses antibiotic feed additive for promoting growth from January, 2006, therefore, finds
Efficient, the green and safe feed addictive for increasing rabbit hair stand density with exploitation comes substitute antibiotics and chemicals, is
Improve the important link of Pili in Fetus of Haired Rabbit production performance.Existing research confirm, Chinese herbal feed additive because its green natural, have it is more
Kind of biological function, have no toxic side effect, the advantages such as noresidue and become the hot spot of current animal husbandry research.A variety of bacillus can
It is all significant to the maintenance and growth and breeding of animal normal physiological condition to generate a variety of nutriments.
Summary of the invention
The present invention provides a kind of its application methods of the feed addictive of raising Pili in Fetus of Haired Rabbit production performance.The feed addictive
Using yeast aspergillus culture D3 as diluent, compounding bacillus subtilis, yeast selenium, methionine, taurine and ginger powder, each original
Expect collective effect, can promote the lipid-metabolism of Pili in Fetus of Haired Rabbit, improves immunity and resistance to oxidation, promote the growth of Pili in Fetus of Haired Rabbit, especially
It is the follicle population that can increase long haired rabbit skin skin tissue, improves the wool production of Pili in Fetus of Haired Rabbit.Basal diet adds the feed when preparing
Antibiotic in the alternative daily ration of additive, to improve Pili in Fetus of Haired Rabbit production performance and the general level of the health.
The technical scheme is that a kind of feed addictive for improving Pili in Fetus of Haired Rabbit production performance, characterized in that every 1kg
The component and content of feed addictive are as follows: bacillus subtilis 1500~250,000,000,000,8~12g of taurine, ginger powder 280~
320g, 12~20g of methionine, yeast selenium 0.8~1.2g, D3 (yeast aspergillus culture) surplus.
Preferably, the component and content of every 1kg feed addictive are as follows: bacillus subtilis 200,000,000,000, taurine 10g,
Ginger powder 300g, methionine 16g, yeast selenium 1g, D3 surplus.
Wherein,
Bacillus subtilis is provided by bacillus subtilis powder, it is desirable that viable count >=20,000,000,000/g of bacterium powder product.
Ginger powder is the powder worn by the ginger after drying, and crosses 80 meshes.
Total Se content requirement >=1000mg/kg, organic selenium content >=95% in yeast selenium.It is preferred that patent of invention
201010185083.8 (denomination of invention: one plant with stronger organic selenium tolerance, enrichment and conversion capability saccharomycete and its answer
With) in yeast selenium.
Wherein, the component and weight ratio of D3 are as follows: saccharomyces cerevisiae solid culture 25~35%, aspergillus niger solid culture 30
~40% and aspergillus oryzae solid culture 30~40%.Optimal proportion are as follows: saccharomyces cerevisiae solid culture 30%, aspergillus niger solid
Culture 35% and aspergillus oryzae solid culture 35%.
Wherein saccharomyces cerevisiae solid culture is the saccharomyces cerevisiae for being CCTCC NO:M2015209 by deposit number
(Saccharomycescerevisiae) BLNJ03 uses wheat bran for primary raw material (wheat bran 90%, maize flour 3%, dregs of beans 7%)
It produces to obtain through solid fermentation.Aspergillus niger solid culture is the aspergillus niger for being CCTCC NO:M2015722 by deposit number
(Aspergillusniger) BLCC6-0009 produces to obtain using wheat bran solid fermentation.Aspergillus oryzae solid culture is by meter Qu
Mould (Aspergillusoryzae) CICC2174 (being purchased from Chinese industrial Culture Collection) uses wheat bran solid fermentation
Production obtains.
The preparation method of above-mentioned three kinds of solid cultures is shown in application for a patent for invention, application number: CN201610452514.X, hair
A kind of bright title: granular pattern probiotics and preparation method thereof that ruminant production performance can be improved.It is solid by above-mentioned three kinds
Body culture raw material, which is crushed to, to be stirred evenly by the fine powder of 20 meshes, spare.Through detecting, the cellulose of mixture D 3
Enzyme activity >=500U/g, neutral protease vigor >=300U/g, amylase activity >=300U/g, Xylanase activity >=200U/
g。
Preparation method: being crushed to 200 meshes for each raw material of feed addictive, spare after mixing.
Application method: adding when basal diet is prepared, and additive amount is the 5 ‰ of Pili in Fetus of Haired Rabbit daily ration total weight, and full price is made
Particulate material feeding.
Each raw material effect:
Bacillus subtilis: there is strong resistance, high temperature resistant, the easily unique biological characteristics such as storage, be national permission
The feed microbe strain used.Take oxygen by force with biology, antagonism pathogenic microorganisms improves inside and outside ecological environment and enhancing body
The effect of immunity, while can produce a variety of enzymes, promote animal digestion enzymatic activity, has effects that promote body growth.
Taurine: being a kind of half required, free amino acid in animal body as a kind of sulfur-containing amino acid.With the machine of raising
The antioxidant levels of body improve lipid-metabolism, improve immunity, improve growth of animals or poultry, improve reproductive performance, promote feeding etc. raw
Object function, in livestock and poultry breeding industry using more and more extensive.
Ginger powder: being a kind of natural green feed additive for having both nutrition and health care dual function, has and increases animal
Feed intake improves feed nutrient digestive utilization ratio, promotes growth of animal, improves livestock products quality, and it is anti-oxidant to improve animal body
With the functions such as immune level, while having the function of a variety of biological healths such as reducing blood lipid, antibacterial, antitumor, as replacing for antibiotic
Dai Pin is with good development and application prospects.
Methionine: being one of amino acid necessary to growth of animal, has and promotes growth of animal, improves immunity, enhancing
The effect of body anti-oxidation function, while being also the important essential amino acid of fur-bearing animal body, growth of fur-bearing animals is developed
It plays a significant role.
Yeast selenium: it is the inorganic selenium that the forms such as sodium selenite are added during Yeast Cultivation, makes selenium with the shape of organic selenium
Formula (selenium methionine, cystine selenium) is enriched in yeast and a kind of microbial fermentation product for producing.Yeast selenium can improve poultry
Fowl growth and antioxygenic property, improve immune function and meat.
D3: using the final product after yeast, aspergillus fermentation wheat bran, dregs of beans etc., metabolizable generation cellulase, albumen
Enzyme, amylase etc., and effectively molecular peptide, vitamin, amino acid, minerals etc., form compound substance, provide nutrition.It can promote
It is digested and assimilated into feed nutrient, improves efficiency of feed utilization, promote digestion and metabolism, promote body growth.
Beneficial effects of the present invention: above-mentioned several raw materials are carried out prescription and feed addictive are made by the present invention, and each raw material is total
Same-action promotes the lipid-metabolism of Pili in Fetus of Haired Rabbit, improves immunocompetence and oxidation resistance, improves body growth correlation thyroid gland and swashs
It is plain horizontal, promote the growth of Pili in Fetus of Haired Rabbit, increase the follicle population of long haired rabbit skin skin tissue, improves the blood rabbit hair and grow correlation factor
Para-insulin like growth factor 1 and melatonin level improve the wool production of Pili in Fetus of Haired Rabbit.
Detailed description of the invention
Fig. 1 is different group Pili in Fetus of Haired Rabbit skin follicle cross cut structure HE dyeing × 100.Wherein A:1 group；B:2 group；C:3 group.
Specific embodiment
Embodiment 1
Proportion: bacillus subtilis powder (50,000,000,000/g of viable count) 4g, taurine 10g, ginger powder 300g, methionine
16g, yeast selenium 1g, D3 surplus.Wherein, the component and weight ratio of D3 are as follows: saccharomyces cerevisiae solid culture 30%, aspergillus niger solid
Culture 35% and aspergillus oryzae solid culture 35%.
Wherein saccharomyces cerevisiae solid culture is the saccharomyces cerevisiae for being CCTCC NO:M2015209 by deposit number
(Saccharomycescerevisiae) BLNJ03 uses wheat bran for primary raw material (wheat bran 90%, maize flour 3%, dregs of beans 7%)
It produces to obtain through solid fermentation.Aspergillus niger solid culture is the aspergillus niger for being CCTCC NO:M2015722 by deposit number
(Aspergillusniger) BLCC6-0009 produces to obtain using wheat bran solid fermentation.Aspergillus oryzae solid culture is by meter Qu
Mould (Aspergillusoryzae) CICC2174 (being purchased from Chinese industrial Culture Collection) uses wheat bran solid fermentation
Production obtains.The preparation method of above-mentioned three kinds of solid cultures is shown in application for a patent for invention, application number: CN201610452514.X,
A kind of denomination of invention: granular pattern probiotics and preparation method thereof that ruminant production performance can be improved.By above-mentioned three kinds
Solid culture raw material, which is crushed to, to be stirred evenly by the fine powder of 20 meshes, spare.Through detecting, the fiber of mixture D 3
Plain enzyme activity >=500U/g, neutral protease vigor >=300U/g, amylase activity >=300U/g, Xylanase activity >=
200U/g.Similarly hereinafter.
Preparation method: being crushed to 200 mesh for above-mentioned raw materials, spare after mixing.
Application method: adding when basal diet is prepared, and additive amount is the 5 ‰ of Pili in Fetus of Haired Rabbit daily ration total weight, and full price is made
Particulate material feeding.
Embodiment 2: feeding effect
Or so August age, weight Pili in Fetus of Haired Rabbit 120 (male and female is fifty-fifty) of similar test is selected to be randomly divided into after unified cropping
3 groups, every group 40 (male and female is fifty-fifty).Using basal diet (table 1) as blank control group (i.e. 3 groups), and in the base of basal diet
The compound additive for adding 5 ‰ formulas 1 and formula 2 on plinth respectively, is made 1 group and 2 groups of full-valence pellet feeds carry out feed addition
The screening of agent, each group of formula are as follows.It tests the outer rabbit home single cage in rabbit room to raise, feeds above-mentioned 1-3 group feed respectively, free water,
Each group individual feed consumption rate is counted weekly.At the end of 1 feeding hair phase (73 days), each group test rabbit unifies cropping, and measurement weight produces hair
Amount counts feed consumption rate, calculates material hair ratio；Acquire the horizontal situation of change of index of correlation in samples for analysis of serum；Dermal tissue harvesting
Make slice analysis follicle population.
Three groups of designs:
1 group: (table 1) adds 5 ‰ formulas 1 respectively on the basis of basal diet.Formula 1: bacillus licheniformis 200,000,000,000/
kg；200,000,000,000/kg of bacillus subtilis；Lactic acid bacteria spray powder 100g；Taurine 50g；Methionine 30g；Sodium sulphate 30g；Sulfuric acid
Zinc 1g；Manganese sulfate 1g；Yeast selenium 1g；D3 (yeast aspergillus culture) polishing is to 1000g.
2 groups: (table 1) adds 5 ‰ formulas 2 respectively on the basis of basal diet.Formula 2: bacillus subtilis 200,000,000,000/
kg；Taurine 10g；Ginger powder 300g；Methionine 16g；Yeast selenium 1g；D3 polishing is to 1000g.
3 groups (control group): basal diet is control group.
1 basal diet of table and trophic level
Note: premix is containing vitamin A, D3, E, B6, B12, niacin, choline chloride, iron, manganese, zinc, copper, iodine, selenium, calcium
The mixture of product composition.
Data carry out one-way analysis of variance using SPSS Statistics 17.0, as a result with the shape of means standard deviation
Formula provides.Single rabbit hair profit, single gross profit=124 yuan/kg × wool production mean value that is only averaged are calculated according to current market price
(kg)-feed consumption rate mean value (kg) × (1.6 yuan/kg+ be formulated 1 additive amount (kg) × 13.23 yuan/kg or formula 2 additive amounts (kg) ×
9.49 yuan/kg).Detailed results are tested as shown in table 2-7 and Fig. 1.
The production performance of the different group Pili in Fetus of Haired Rabbit of table 2
Note: same column shoulder, which infuses the identical person of letter, indicates that difference is not significant (P>0.05), letter difference person's expression significant difference (P<
0.05), similarly hereinafter.
As shown in table 2, basal diet control group is compared, the answering containing taurine and ginger powder simultaneously of present invention addition 5 ‰
It closes additive (2 groups), the production performance of Pili in Fetus of Haired Rabbit can be made to increase substantially, wherein hair rabbit weight and wool production significantly improve, material
For hair than significantly reducing, the gross profit of single rabbit improves 3.7 yuan, improves the final economic benefit of Pili in Fetus of Haired Rabbit.And 5 ‰ are only added containing ox
Compared with basal diet control group, wool production significantly improves the compound additive (1 group) of sulfonic acid, and material hair ratio is remarkably decreased, hair rabbit
Weight improves not significant, 2.12 yuan of the gross profit raising of single rabbit.
The changes of contents (mmol/L) of the different group Pili in Fetus of Haired Rabbit serum TCs of table 3, TG, HDL and LDL
As shown in table 3, only the compound additive containing taurine (2 groups) and addition 5 ‰ contain simultaneously for addition 5 ‰ in daily ration
The compound additive (1 group) of taurine and ginger powder can reduce serum total cholesterol (TC) and low close compared with basal diet group
Lipoprotein (LDL) level is spent, lipid-metabolism is promoted.
The different groups of table 4 become mildewed the changes of contents (g/L) of IgA, IgG and IgM in rabbit anteserum
Such as table 4 it can be seen that after compound additive of the present invention addition 5 ‰ simultaneously containing taurine and ginger powder (2 groups)
Compared with basal diet control group, it is remarkably improved the content of IgA and IgG in serum, improves immune function.And only add 5 ‰
After compound additive containing taurine (1 group) compared with basal diet control group, IgA and IgG index slightly improve, be immunized function
It can improve unobvious.
The different groups of table 5 become mildewed the changes of contents of SOD, T-AOC and MDA in rabbit anteserum
Such as table 5 it can be seen that after compound additive (2 groups) of the present invention addition 5 ‰ simultaneously containing taurine and ginger powder,
Compared with basal diet control group, it is remarkably improved serum superoxide dismutases (SOD) and total antioxidant capacity (T-AOC) is living
Property, and malonaldehyde (MDA) content is significantly reduced, enhance the oxidation resistance of body.And 5 ‰ are only added containing the compound of taurine
After additive (1 group) compared with basal diet control group, SOD activity is significantly improved, T-AOC activity slightly improves, and MDA content is aobvious
Decline is write, the oxidation resistance of body is dramatically increased.Meanwhile compared to only adding the compound additive containing taurine, the present invention
The addition compound additive containing taurine and ginger powder simultaneously is remarkably improved serum superoxide dismutases (SOD) and always
Oxidation resistance (T-AOC) activity, and malonaldehyde (MDA) content is significantly reduced, enhance the oxidation resistance of body.
The different groups of table 6 become mildewed the changes of contents of T4, IGF-1 and MTL in rabbit anteserum
As can be seen from Table 6: after compound additive of the present invention addition 5 ‰ simultaneously containing taurine and ginger powder (2 groups),
Compared with basal diet control group, thyroid hormone (T4) level can be improved, promote the growth and development of Pili in Fetus of Haired Rabbit；Serum can be improved
Middle type-1 insulin like growth factor (IGF-1) and melatonin (MTL) are horizontal, promote the growth and development of the rabbit hair.And only add 5 ‰
For compound additive (1 group) containing taurine compared with basal diet control group, the raising of T4, IGF-1 and MTL index is not significant,
The growth and development of the rabbit hair cannot be remarkably promoted.
The follicle population of the different group long haired rabbit skin skin tissues of table 7
From table 7 and Fig. 1 it can be seen that after compound additive of the present invention addition 5 ‰ simultaneously containing taurine and ginger powder
(2 groups) can obviously increase the density of hair follicle in Pili in Fetus of Haired Rabbit skin compared with basal diet control group, final realization wool production
It improves.And after only adding 5 ‰ compound additives containing taurine (1 group) compared with basal diet control group, follicle population is mentioned
It is high but significant level cannot be reached.
It can be seen that Taurine, ginger powder, the related additives such as probiotics and bioactive enzyme are subjected to compatibility simultaneously,
Respective advantage can not only be given full play to, and there is synergistic effect, can obviously improve the lipid-metabolism of Pili in Fetus of Haired Rabbit, is improved immune
Body growth correlation thyroid hormones level can be improved in ability and oxidation resistance, and the hair follicle for increasing long haired rabbit skin skin tissue is close
Degree improves blood rabbit hair growth correlation factor IGF-1 and MTL level, so that Pili in Fetus of Haired Rabbit weight and wool production be made to significantly improve.
Embodiment 3
Proportion: bacillus subtilis powder (100,000,000,000/g of viable count) 2g, taurine 12g, ginger powder 280g, methionine
15g, yeast selenium 1g, D3 surplus.Wherein, the component and weight ratio of D3 are as follows: saccharomyces cerevisiae solid culture 30%, aspergillus niger solid
Culture 40% and aspergillus oryzae solid culture 30%.
Preparation method: being crushed to 200 mesh for above-mentioned raw materials, spare after mixing.
Application method: adding when basal diet is prepared, and additive amount is the 5 ‰ of Pili in Fetus of Haired Rabbit daily ration total weight, and full price is made
Particulate material feeding.
Embodiment 4
Proportion: bacillus subtilis powder (20,000,000,000/g of viable count) 10g, taurine 9g, ginger powder 310g, methionine
14g, yeast selenium 1g, D3 surplus.Wherein, the component and weight ratio of D3 are as follows: saccharomyces cerevisiae solid culture 30%, aspergillus niger solid
Culture 30% and aspergillus oryzae solid culture 40%.
Preparation method: being crushed to 200 mesh for above-mentioned raw materials, spare after mixing.
Application method: adding when basal diet is prepared, and additive amount is the 5 ‰ of Pili in Fetus of Haired Rabbit daily ration total weight, and full price is made
Particulate material feeding.
Claims (7)
1. a kind of feed addictive for improving Pili in Fetus of Haired Rabbit production performance, characterized in that
The component and content of every 1kg feed addictive are as follows: bacillus subtilis 1500~250,000,000,000,8~12g of taurine are raw
280~320g of ginger powder, 12~20g of methionine, yeast selenium 0.8~1.2g, D3 surplus；
The component and weight ratio of the D3 are as follows: saccharomyces cerevisiae solid culture 25~35%, aspergillus niger solid culture 30~
40% and aspergillus oryzae solid culture 30~40%.
2. a kind of feed addictive for improving Pili in Fetus of Haired Rabbit production performance as described in claim 1, characterized in that every 1kg
The component and content of feed addictive are as follows: bacillus subtilis 200,000,000,000, taurine 10g, ginger powder 300g, methionine 16g,
Yeast selenium 1g, D3 surplus.
3. a kind of feed addictive for improving Pili in Fetus of Haired Rabbit production performance as described in claim 1, characterized in that the group of the D3
Point and weight ratio are as follows: saccharomyces cerevisiae solid culture 30%, aspergillus niger solid culture 35% and aspergillus oryzae solid culture
35%.
4. a kind of feed addictive of raising Pili in Fetus of Haired Rabbit production performance as described in any one of claim 1-3, feature
It is that the bacillus subtilis is provided by bacillus subtilis powder, it is desirable that viable count >=20,000,000,000/g of bacterium powder product.
5. a kind of feed addictive of raising Pili in Fetus of Haired Rabbit production performance as described in any one of claim 1-3, feature
It is that the ginger powder is the powder worn by the ginger after drying, crosses 80 meshes.
6. a kind of feed addictive of raising Pili in Fetus of Haired Rabbit production performance as described in any one of claim 1-3, feature
It is total Se content requirement >=1000mg/kg, organic selenium content >=95% in the yeast selenium.
7. a kind of feed addictive of raising Pili in Fetus of Haired Rabbit production performance as described in any one of claim 1-3, feature
It is that each component of feed addictive was crushed to 200 meshes, it is spare after mixing.
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| CN112006170A (en) * | 2020-07-31 | 2020-12-01 | 黑龙江省农业科学院畜牧研究所 | Feed additive for promoting production performance of fur-bearing animals and application thereof |
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| CN1095898A (en) * | 1993-06-03 | 1994-12-07 | 山东大学 | A kind of preparation method of basic feed for rabbits |
| CN104082555A (en) * | 2014-06-10 | 2014-10-08 | 芜湖县绿色草原兔业养殖专业合作社 | Rabbit feed capable of preventing cold and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1095898A (en) * | 1993-06-03 | 1994-12-07 | 山东大学 | A kind of preparation method of basic feed for rabbits |
| CN104082555A (en) * | 2014-06-10 | 2014-10-08 | 芜湖县绿色草原兔业养殖专业合作社 | Rabbit feed capable of preventing cold and preparation method thereof |
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