CN106860495A - Fat-reducing liver-protecting Chinese medicine composition - Google Patents
Fat-reducing liver-protecting Chinese medicine composition Download PDFInfo
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- CN106860495A CN106860495A CN201510910477.8A CN201510910477A CN106860495A CN 106860495 A CN106860495 A CN 106860495A CN 201510910477 A CN201510910477 A CN 201510910477A CN 106860495 A CN106860495 A CN 106860495A
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Abstract
The invention discloses a kind of fat-reducing liver-protecting Chinese medicine composition, belong to technical field of traditional Chinese medicine.Fat-reducing liver-protecting Chinese medicine composition disclosed by the invention, is medicament, health products or the food being made as raw material with radix bupleuri cauline leaf, the root of herbaceous peony, Radix Glycyrrhizae, hawthorn, the red sage root, rhizoma alismatis.Show according to clinical verification, Chinese medicine composition long-term use of the invention can be with liver protecting, softening blood vessel, reducing blood lipid, to mid-aged population because of fatty liver caused by glucose -lipid metabolism disorder, high fat of blood, the symptom such as vascular sclerosis and disease have significant preventive and therapeutic action.
Description
Technical field
The invention discloses a kind of fat-reducing liver-protecting Chinese medicine composition, belong to food, health products or the field of Chinese medicines.
Background technology
Modern way of life changes the physical and mental health that the metabolic disease for causing has had a strong impact on people, causes great society
Burden, increasing people suffers from glucose -lipid metabolism disorder illness, and the elderly is particularly acute.Modern medicine thinks that glycolipid metabolism is disorderly
It is disorderly the major pathologic features of metabolic syndrome, is also the key element of multiple risk factors in metabolic syndrome, it is headstroke, hat
The pathologic basis and main risk factor of worry, miocardial infarction and other various chronic diseases, it is most common to have hyperlipemia, sugar
Urine disease, fatty liver, hypertension, Impaired Glucose Tolerance Treated（IGI), fasting blood-glucose detraction（IFG) etc., for its prevention and treatment, medical science
Not yet there is the significant medicine of therapeutic action on boundary.
The traditional Chinese medical science thinks, glucose -lipid metabolism disorder relevant disease belong to the traditional Chinese medical science quench one's thirst, the obstruction of qi in the chest, palpitaition, headache, dizziness, phlegm wet etc.
Category, main pathogenesis are liver dysfunction, cause visceral dysfunction, body fluid to lose the syndrome caused by defeatedization.Liver controlling conveyance and dispersion,
Catharsis is " dredging ", and " happy ", the meaning of " bar reaches ", that is to say, that under normal physiological condition, irritability have dredging, what bar reached
Characteristic, this function is mainly reflected in dredging of the liver to mechanism of qi, and " mechanism of qi " is the lifting discrepancy motion of gas.The internal organs of body, warp
The activities such as network, organ, the lifting relied entirely in gas comes in and goes out and moves.And the physilogical characteristics of liver are main liters, active, so, this is right
Dredging, fluent, liter hair in mechanism of qi are undoubtedly an important factor.Therefore, whether the catharsis function of liver is normal, for gas
Balance coordination between lifting comes in and goes out plays a part of regulation.Blood-fat and blood sugar, just as ying blood body fluid, is the precise and tiny thing of water paddy metaplasia
Matter, the catharsis function of liver is normal, then QI movement being in harmonious way, and lifting is suitable, qi and blood and tune, and channels and collaterals tonneau, internal organs organ function is normal.Water
Paddy is precise and tiny to concentrate blood vessels on, and warm skin moistens foster internal organs bones of the body collectively.Overfeeding delicious food pure wine savoury, sitting are crouched damage temper long, and spleen is not
Dissipate essence, vital essence can not on be attributed to lung and towards hundred arteries and veins, water paddy elite is detained and do not change, soil plug wood is strongly fragrant, strongly fragrant and change heat, and gas consumption hinders Tianjin, clearly
Gas does not rise, failure in sending down turbid yin, accumulatively wet raise phlegm, stays and forms the stasis of blood, and phlegm is turbid, hemostasis checks channels and collaterals internal organs causes blood pressure and blood lipoid to raise, and this is
The Basic disease cause interpretation of the cause, onset and process of an illness of glucose -lipid metabolism disorder relevant disease.Therefore, soothing the liver nourishing blood and liver, promoting flow of qi and blood circulation stagnation resolvation is changed turbid lipid-loweringing and is oozed
Wet is the base therapy and Precautionary Principle of glucose -lipid metabolism disorder.
The crucial interpretation of the cause, onset and process of an illness that Traditional Chinese Medicine University Of Guangzhou Guo Jiao etc. is also considered as metabolic disease is " liver loses pivot use ", it is proposed that " with
Liver is pivot, adjust it is esterified turbid " theory and " hinge hepatic metabolism regulating system " concept, it is believed that liver is the metabolism that hyperlipidemia is representative
Property disease incidence internal organs (liver spleen kidney）Core and hinge, for the traditional Chinese medicine prevention of metabolic disease provides thinking.
Therefore, soothing the liver nourishing blood and liver, promoting flow of qi and blood circulation stagnation resolvation, it is the new direction for treating glucose -lipid metabolism disorder to change turbid lipid-loweringing.West
Though medicine instant effect in terms of glucose -lipid metabolism disorder illness is treated, cures the symptoms, not the disease, toxic and side effect is big, increases new to patient
Burden, such as：Simvastatin Treatment hyperlipidemia lipid-lowering effect is fast, but has certain damaging action to liver function；Chinese herbal medicine specimen is simultaneous
Control, toxic and side effect is small, mid-aged population is more suitable in terms of glucose -lipid metabolism disorder illness is treated.So, there is provided it is a kind of extensive
Be adapted to mid-aged population and can the Chinese medicine preparation of effectively fat-reducing liver-protecting be a worth problem studied.
Radix bupleuri is large conventional Chinese medicine, and States Pharmacopoeia specifications radix bupleuri only root can just be used as medicine, so general with radix bupleuri at present
Root is used as medicine, and there is antipyretic, analgesia, calmness, anti-inflammatory etc. to act on for its root.Generally believe that radix bupleuri all herbal medicine can reduce the matter of medicine
Amount, so harvested in the early spring being abandoned radix bupleuri cauline leaf as discarded object often.In recent years, gradually carried out to total flavone both at home and abroad
The pharmacological research of leaf, it is found that radix bupleuri cauline leaf has strengthen immunity, antiviral, anti-inflammatory, analgesia and anti-oxidant etc. acts on.Cause
This radix bupleuri cauline leaf goes out of use, and not only causes the huge wasting of resources, also causes economic loss to peasant, is highly detrimental to radix bupleuri
The development of industry.
For application of the radix bupleuri cauline leaf in specific medicine, also nobody is related to.And also have no with total flavone both at home and abroad at present
Leaf is made document report and the patent application of medicine, health products or food for primary raw material.
The content of the invention
The purpose of the present invention is to solve the shortcomings of the prior art, change radix bupleuri industry now and the utilization of radix bupleuri cauline leaf is not good at
Situation, while making up blank of the radix bupleuri cauline leaf in terms of medicinal application, there is provided radix bupleuri cauline leaf prepare with fat-reducing liver-protecting make
Application in Chinese medicine composition, it is further provided one kind wants one of composition based on radix bupleuri cauline leaf, it is old in being widely used in
Year, crowd had the liver protecting of positive and sure effect, and softening blood vessel changes the Chinese medicine composition of turbid lipid-loweringing.
In order to realize foregoing invention purpose, the technical solution adopted by the present invention is as follows：
- kind of fat-reducing liver-protecting Chinese medicine composition, it is medicament, health products or the food for wanting raw material to be made based on radix bupleuri cauline leaf.
Further, radix bupleuri cauline leaf can be used with one or more drug matching of regulation glycolipid metabolism, such as：It is the root of herbaceous peony, sweet
Grass, hawthorn, the red sage root, rhizoma alismatis, the Radix Astragali, ganoderma lucidum, dandelion, the root of kudzu vine, turmeric, rhizoma atractylodis, lotus leaf, pawpaw, bluish dogbane, the root of bidentate achyranthes, mast,
Matrimony vine, chrysanthemum, glutinous rehmannia, rhizoma Gastrodiae, yncaria stem with hooks, keel, oyster, mother-of-pearl, tortoiseshell, the root of large-flowered skullcap, play both sides of the street, the shell of seaear, selfheal etc..
Further, radix bupleuri cauline leaf of the present invention is the tender point of radix bupleuri.
The fat-reducing liver-protecting Chinese medicine composition that the present invention is provided, raw material also includes hawthorn, the red sage root, rhizoma alismatis.
Best, fat-reducing liver-protecting Chinese medicine composition of the invention, raw material also includes the root of herbaceous peony, Radix Glycyrrhizae.The Chinese medicine composition with
Radix bupleuri cauline leaf, the root of herbaceous peony are altogether monarch drug in a prescription, with hawthorn, the red sage root altogether as ministerial drug, with rhizoma alismatis as adjutant, with Radix Glycyrrhizae to make medicine.Radix bupleuri leaf 5
The root of herbaceous peony, soothing liver-qi stagnation, nourishing blood and liver, hawthorn scattered stasis change turbid lipid-loweringing, and red sage root promoting blood circulation, relieving restlessness that clears away heart-fire, rhizoma alismatis Li Shui oozes
It is wet, expel the heat-evil, change turbid lipid-loweringing, Radix Glycyrrhizae is clearing heat and detoxicating, coordinating the drug actions of a prescription.All medicines share, with significant fat-reducing liver-protecting effect.
Further, the weight portion of each raw material is in above-mentioned fat-reducing liver-protecting Chinese medicine composition：10-50 parts of radix bupleuri cauline leaf, the root of herbaceous peony
8-30 parts, Radix Glycyrrhizae 2-15 parts, hawthorn 20-60 parts, red sage root 20-60 parts, rhizoma alismatis 2-12 parts.
Preferably, the weight portion of each raw material is in fat-reducing liver-protecting Chinese medicine composition of the invention：12-40 parts of radix bupleuri cauline leaf,
Root of herbaceous peony 9-20 parts, Radix Glycyrrhizae 3-10 parts, hawthorn 25-45 parts, red sage root 25-45 parts, rhizoma alismatis 5-10 parts.
It is furthermore preferred that the weight portion of each raw material is in fat-reducing liver-protecting Chinese medicine composition of the invention：Radix bupleuri cauline leaf 15-30
Part, root of herbaceous peony 10-15 parts, Radix Glycyrrhizae 4-8 parts, hawthorn 27-35 parts, red sage root 26-40 parts, rhizoma alismatis 7-9 parts.
Most preferably, the weight portion of each raw material is in fat-reducing liver-protecting Chinese medicine composition of the invention：20 parts of radix bupleuri cauline leaf, in vain
12 parts of Chinese herbaceous peony, 5 parts of Radix Glycyrrhizae, 30 parts of hawthorn, 30 parts of the red sage root, 8 parts of rhizoma alismatis.
Application of the radix bupleuri cauline leaf in the Chinese medicine composition with fat-reducing liver-protecting effect is prepared.
The medicament of fat-reducing liver-protecting Chinese medicine composition of the invention, health products or food, can constitute by by above-mentioned formula
Raw material through extraction or other modes processing, be made pharmaceutically active substance, with the material as raw material, it is necessary to when addition medicine,
Health products or food acceptable carrier or auxiliary material, are made according to routine techniques.The active material can be by carrying respectively
Take raw material to obtain, it is also possible to obtained by the common raw material that extracts, it is also possible to obtain by other means, such as：By crushing, pressing
Squeezing, grinding, sieving, extraction, water extraction, alcohol extracting, ester the method such as put forward, chromatograph and obtaining, and these active materials can be medicinal extract form
Material, can be that dry extract can also be liquid extract, and different according to preparation need to determine to be made different concentration.
Fat-reducing liver-protecting Chinese medicine composition of the invention, its pharmaceutically active substance is obtained by extracting processing, and processing can
With using any combinations in the above method.
A kind of preparation method of fat-reducing liver-protecting Chinese medicine composition of the invention, comprises the following steps：
(1) radix bupleuri cauline leaf, the root of herbaceous peony, Radix Glycyrrhizae, hawthorn, the red sage root, rhizoma alismatis are weighed in proportion；
(2) by step（1) raw material in is prepared into extract or crude drug powder in the following manner：
A) extract or crude drug powder are prepared into respectively,
B)-kind or several raw materials be prepared by mixing into extract or crude drug powder,
C) whole raw materials are prepared by mixing into extract or crude drug powder；
(3) by step（2) extract of gained raw material or crude drug powder mixing, are made acceptable various pharmaceutical dosage forms, health care in
Product or food.
Further, step in the preparation method of fat-reducing liver-protecting Chinese medicine composition of the invention（2) include：Take step（1) in
Radix bupleuri cauline leaf, the root of herbaceous peony, Radix Glycyrrhizae, hawthorn, the red sage root, rhizoma alismatis, mixing, extract, obtain extract.
Fat-reducing liver-protecting Chinese medicine composition of the invention according to common process add customary adjuvant or carrier can be made decoction,
Medicinal tea, beverage, oral liquid, mixture, granule, capsule, tablet, syrup, lozenge, chewable tablets, electuary, pill, dripping pill or note
One or more product such as agent is penetrated to be used.For example, radix bupleuri cauline leaf is weighed in proportion, the root of herbaceous peony, Radix Glycyrrhizae, hawthorn, the red sage root, pool
Rush down, above-mentioned raw materials are crushed, be well mixed, every part, by a certain amount of health paper bag for loading and making tea, is packed after sealing, that is, be made
Medicinal tea；Or radix bupleuri cauline leaf is weighed in proportion, the root of herbaceous peony, Radix Glycyrrhizae, hawthorn, the red sage root, rhizoma alismatis is well mixed, is carried using decocting cooking method
Thick paste is taken, drying under reduced pressure is crushed, and obtains dry extract, adds auxiliary material, is well mixed, and granulation is encapsulated, obtains final product capsule.
Compared with prior art, the beneficial effects of the invention are as follows：
A kind of fat-reducing liver-protecting Chinese medicine composition of the invention, there is provided Chinese traditional medicine composition one of with radix bupleuri cauline leaf as constituent
Thing, realizes the comprehensive utilization of radix bupleuri, compensate for radix bupleuri cauline leaf medicinal application in terms of blank, composition of the invention
Liver protecting, softening blood vessel, lipid-lowering effect is notable, Small side effects, to mid-aged population because of fat caused by glucose -lipid metabolism disorder
The symptoms such as liver, high fat of blood, vascular sclerosis and disease have significant preventive and therapeutic action.And show by clinical observation, its is total
It is efficient up to 98. 18%.
Fat-reducing liver-protecting Chinese medicine composition of the invention can both be made health products, food, and medicine can be made again, open up significantly
Open up and used scope.Medicine material of the invention is all easily commercially available, and preparation method is simple, with very strong popularization and application
Value.
Specific embodiment
With reference to test example and specific embodiment, the present invention is described in further detail.But this should not be understood
For the scope of above-mentioned theme of the invention is only limitted to following embodiment, all technologies realized based on present invention belong to this
The scope of invention.
Following embodiments and experimental technique, unless otherwise specified, are conventional method；The reagent and medicine, such as without spy
Different explanation, commercially obtains.
The medicinal tea of embodiment 1
Radix bupleuri cauline leaf 10g, root of herbaceous peony 8g, Radix Glycyrrhizae 5g, hawthorn 20g, red sage root 20g, rhizoma alismatis 8g, above-mentioned raw materials are crushed, and mixing is equal
Even, every part of 5g loads the health paper bag made tea, and is packed after sealing, that is, be made medicinal tea.
The beverage of embodiment 2
Radix bupleuri cauline leaf 30g, root of herbaceous peony 15g, Radix Glycyrrhizae 10g, hawthorn 40g, red sage root 40g, rhizoma alismatis 10g, are well mixed, and are boiled using decocting
Method extracts thick paste, and drying under reduced pressure is crushed, and obtains dry extract.
Above-mentioned dry extract is taken, routinely process, i.e. ,-degassing-pasteurize-is filling-cold comprising allotment-homogeneous
The step such as but, you can obtain finished beverage.
The capsule of embodiment 3
Radix bupleuri cauline leaf 40g, root of herbaceous peony 20g, Radix Glycyrrhizae 15g, hawthorn 50g, red sage root 40g, rhizoma alismatis 12g, are well mixed, and are boiled using decocting
Method extracts thick paste, and drying under reduced pressure is crushed, and obtains dry extract.
Above-mentioned dry extract is taken, talcum powder, starch are added according to common process, be well mixed, granulation is encapsulated, obtains final product
Capsule.
The tablet of embodiment 4
Radix bupleuri cauline leaf 50g, root of herbaceous peony 20g, Radix Glycyrrhizae 15g, hawthorn 60g, red sage root 60g, rhizoma alismatis 12g, are well mixed, and are boiled using decocting
Method extracts thick paste, and drying under reduced pressure is crushed, and obtains dry extract.
Above-mentioned dry extract is taken, calcium carbonate, starch are added according to common process, be well mixed, compressing tablet obtains final product tablet.
The oral liquid of embodiment 5
Radix bupleuri cauline leaf 25g, root of herbaceous peony 12g, Radix Glycyrrhizae 5g, hawthorn 30g, red sage root 30g, rhizoma alismatis 8g, are well mixed, using decocting cooking method
Thick paste is extracted, drying under reduced pressure is crushed, and obtains dry extract.
Above-mentioned dry extract is taken, is dissolved in water according to common process, adjust pH value, add solubilizer, preservative, flavoring
Agent, it is filling, it is made oral liquid.
Claims (6)
1. a kind of fat-reducing liver-protecting Chinese medicine composition, it is characterised in that it be want raw material to be made based on radix bupleuri cauline leaf medicament, protect
Strong product or food.
2. fat-reducing liver-protecting Chinese medicine composition according to claim 1, it is characterised in that the raw material of the Chinese medicine composition is also
Including hawthorn, the red sage root, rhizoma alismatis.
3. fat-reducing liver-protecting Chinese medicine composition according to claim 2, it is characterised in that the raw material of the Chinese medicine composition is also
Including the root of herbaceous peony, Radix Glycyrrhizae.
4. fat-reducing liver-protecting Chinese medicine composition according to claim 6, it is characterised in that each raw material in Chinese medicine composition
Weight portion is：20 parts of radix bupleuri cauline leaf, 12 parts of the root of herbaceous peony, 5 parts of Radix Glycyrrhizae, 30 parts of hawthorn, 30 parts of the red sage root, 8 parts of rhizoma alismatis.
5. the fat-reducing liver-protecting Chinese medicine composition according to claim any one of 1-7, it is characterised in that：Described medicament, guarantor
Strong product or food are decoction, medicinal tea, beverage, oral liquid, mixture, granule, capsule, tablet, syrup, lozenge, chewable tablets, punching
Agent, pill, dripping pill or injection.
6. a kind of preparation method of the soothing the liver beauty treatment Chinese medicine composition according to claim any one of 1-7, including following step
Suddenly：
Radix bupleuri cauline leaf, the root of herbaceous peony, Radix Glycyrrhizae, hawthorn, the red sage root, rhizoma alismatis are weighed in proportion；
By step（1) raw material in is prepared into extract or crude drug powder in the following manner：
Extract or crude drug powder are prepared into respectively,
- kind or several raw materials be prepared by mixing into extract or crude drug powder,
Whole raw materials are prepared by mixing into extract or crude drug powder；
By step（2) extract of gained raw material or crude drug powder mixing, are made acceptable various pharmaceutical dosage forms, health products in
Or food.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113797282A (en) * | 2020-06-14 | 2021-12-17 | 烟台圣莱恩康复医院有限公司 | Traditional Chinese medicine composition for reducing blood fat and protecting liver for old people and preparation process thereof |
| CN115869365A (en) * | 2022-12-23 | 2023-03-31 | 西藏月王药诊生态藏药科技有限公司 | Preparation ratio and preparation process of lipid-lowering and liver-protecting composition |
-
2015
- 2015-12-10 CN CN201510910477.8A patent/CN106860495A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113797282A (en) * | 2020-06-14 | 2021-12-17 | 烟台圣莱恩康复医院有限公司 | Traditional Chinese medicine composition for reducing blood fat and protecting liver for old people and preparation process thereof |
| CN115869365A (en) * | 2022-12-23 | 2023-03-31 | 西藏月王药诊生态藏药科技有限公司 | Preparation ratio and preparation process of lipid-lowering and liver-protecting composition |
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