CN106728752A - A kind of medicine for treating anemopyretic cold and preparation method thereof - Google Patents

A kind of medicine for treating anemopyretic cold and preparation method thereof Download PDF

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CN106728752A
CN106728752A CN201611235906.7A CN201611235906A CN106728752A CN 106728752 A CN106728752 A CN 106728752A CN 201611235906 A CN201611235906 A CN 201611235906A CN 106728752 A CN106728752 A CN 106728752A
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parts
medicine
vitamin
anemopyretic cold
flavonols
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不公告发明人
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Henan Eight Ling Electronic Technology Co Ltd
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Henan Eight Ling Electronic Technology Co Ltd
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    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A61K31/51—Thiamines, e.g. vitamin B1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives

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Abstract

The invention discloses a kind of medicine for treating anemopyretic cold, it is made up of according to weight portion following raw material：0.5 4 parts of Chai huang granule, 13 parts of qinghaosu, 25 parts of flavonols, 0.5 4 parts of brufen, 36 parts of streptomysin, 5 10 parts of pseudoephedrine, 0.1 1.5 parts of vitamin B1,4 12 parts of vitamin C, 5 12 parts of honey, 5 15 parts of garlic juice, 38 parts of caffeine, 26 parts of glycerine and 15 32 parts of the ethanol solution that volume fraction is 55 70%.The present invention also disclosed the preparation method of the medicine.Raw material sources of the present invention are extensive, preparation process is simple, investment of production equipment low cost, it is adaptable to large-scale industrial production；The component such as brufen, flavonols, pseudoephedrine plays synergy in the present invention, can fundamentally cure anemopyretic cold, instant effect, and therapeutic effect is far superior to existing product and no toxic and side effect, wide market.

Description

A kind of medicine for treating anemopyretic cold and preparation method thereof
Technical field
The present invention relates to a kind of medicine, specifically a kind of medicine for treating anemopyretic cold.
Background technology
Flu, also known as the infection of the upper respiratory tract, is the general name for including nasal cavity, pharynx or acute throat inflammation.Sensu lato flu is not It is a medical diagnosis on disease, but one group of disease, including anemopyretic cold, viral pharyngitis, laryngitis, herpangina, pharynx conjunctiva Heat and bacterial pharyngotonsillitis.The upper sense of narrow sense, also known as anemopyretic cold, is most common acute infections of respiratory tract disease, It is in self limiting more, but incidence is higher.Anemopyretic cold is commonly called as " cold ", also known as acute rhinitis or common cold, more by nose Virus causes, secondly for coronavirus, parainfluenza virus, Respiratory Syncytial Virus(RSV), echovirus, Coxsackie virus etc. cause, It is mainly shown as sniffle, such as sneeze, nasal obstruction and stream clear water sample nasal mucus, can also appear as cough, dry throat, pharynx and itch or scorching hot Sense, or even Postnasal drip sense.Morbidity can have the symptoms such as sneeze, nasal obstruction and stream clear water sample nasal mucus simultaneously or after a few hours.Morbidity 2-3 Nasal mucus retrogradation after it, often with pharyngalgia, shed tears, hypogeusia, unsmooth breath, trachyphonia etc..Although existing Western medicine can treat wind Thermal sensation emits, but cures the symptoms, not the disease, and the toxic and side effect of long-term taking is big, and this is just for patient brings inconvenience.
The content of the invention
It is an object of the invention to provide a kind of medicine for treating anemopyretic cold, to solve to be carried in above-mentioned background technology The problem for going out.
To achieve the above object, the present invention provides following technical scheme：
A kind of medicine for treating anemopyretic cold, is made up of following raw material according to weight portion：Chai huang granule 0.5-4 parts, Qinghaosu 1-3 parts, flavonols 2-5 parts, brufen 0.5-4 parts, streptomysin 3-6 parts, pseudoephedrine 5-10 parts, vitaminB10 .1- 1.5 parts, vitamin C 4-12 parts, honey 5-12 parts, garlic juice 5-15 parts, caffeine 3-8 parts, glycerine 2-6 parts and volume fraction are Ethanol solution 15-32 parts of 55-70%.
As further scheme of the invention：The medicine for treating anemopyretic cold, by following raw material according to weight Part composition：Chai huang granule 2-4 parts, qinghaosu 1.5-3 parts, flavonols 3-5 parts, brufen 2-4 parts, streptomysin 4-6 parts, False path Alkali 7-10 parts, vitaminB10 .4-1.5 parts, vitamin C 7-12 parts, honey 7-12 parts, garlic juice 8-15 parts, caffeine 5-8 parts, Glycerine 3-6 parts and volume fraction are ethanol solution 21-32 parts of 55-70%.
As further scheme of the invention：The medicine for treating anemopyretic cold, by following raw material according to weight Part composition：3 parts of Chai huang granule, 2.5 parts of qinghaosu, 4 parts of flavonols, 3 parts of brufen, 5 parts of streptomysin, 9 parts of pseudoephedrine, dimension life Plain B10.9 parts, 10 parts of vitamin C, 11 parts of honey, 13 parts of garlic juice, 6 parts of caffeine, 5 parts of glycerine and volume fraction are 55- 28 parts of 70% ethanol solution.
The preparation method for treating the medicine of anemopyretic cold, comprises the following steps that：
Step one, to adding ethanol solution in garlic juice, then is added thereto to Chai huang granule, qinghaosu, flavonols and cloth Ibuprofen, mixer is stirred 15-25 minutes with the rotating speed of 60-120rpm at normal temperatures, and stirring seals 2-5 hours and mistake after terminating Filter, obtains the first mixed solution；
Step 2, streptomysin, pseudoephedrine, vitamin B1, vitamin C and glycerine are stirred, and are added while stirring Caffeine, caffeine is added after finishing, and mixer is stirred 20-45 minutes under 30-45 degrees Celsius with 150-240rpm, obtains the Two mixed solutions；
Step 3, honey, the first mixed solution and the second mixed solution is stirred and bottling is filtered, in 100- Cooking disinfection is carried out under 200 degrees Celsius, you can obtain finished product.
Compared with prior art, the beneficial effects of the invention are as follows：Extensively, preparation process is simple is raw for raw material sources of the present invention Produce equipment investment cost low, it is adaptable to large-scale industrial production；The group such as brufen, flavonols, pseudoephedrine in the present invention Synergy is divided, can fundamentally cure anemopyretic cold, instant effect, therapeutic effect has been far superior to existing product and has not had Toxic and side effect, wide market.
Specific embodiment
The technical scheme of this patent is described in more detail with reference to specific embodiment.
Embodiment 1
A kind of medicine for treating anemopyretic cold, is made up of following raw material according to weight portion：0.5 part of Chai huang granule, green grass or young crops 1 part of artemisin, 2 parts of flavonols, 0.5 part of brufen, 3 parts of streptomysin, 5 parts of pseudoephedrine, vitaminB10 .1 parts, 4 parts of vitamin C, 5 parts of honey, 5 parts of garlic juice, 3 parts of caffeine, 2 parts of glycerine and 15 parts of the ethanol solution that volume fraction is 55%.
The preparation method for treating the medicine of anemopyretic cold, comprises the following steps that：
Step one, to adding ethanol solution in garlic juice, then is added thereto to Chai huang granule, qinghaosu, flavonols and cloth Ibuprofen, mixer is stirred 20 minutes with the rotating speed of 60rpm at normal temperatures, and stirring sealing 3 hours and is filtered after terminating, and obtains the One mixed solution；
Step 2, streptomysin, pseudoephedrine, vitamin B1, vitamin C and glycerine are stirred, and are added while stirring Caffeine, caffeine is added after finishing, and mixer is stirred 20 minutes under 30 degrees Celsius with 150rpm, obtains the second mixing molten Liquid；
Step 3, honey, the first mixed solution and the second mixed solution are stirred and bottling is filtered, and are taken the photograph 120 Cooking disinfection is carried out under family name's degree, you can obtain finished product.
Embodiment 2
A kind of medicine for treating anemopyretic cold, is made up of following raw material according to weight portion：2 parts of Chai huang granule, sweet wormwood Element 1.5 parts, 3 parts of flavonols, 2 parts of brufen, 4 parts of streptomysin, 7 parts of pseudoephedrine, vitaminB10 .4 parts, 7 parts of vitamin C, honeybee 7 parts of honey, 8 parts of garlic juice, 5 parts of caffeine, 3 parts of glycerine and 21 parts of the ethanol solution that volume fraction is 60%.
The preparation method for treating the medicine of anemopyretic cold, comprises the following steps that：
Step one, to adding ethanol solution in garlic juice, then is added thereto to Chai huang granule, qinghaosu, flavonols and cloth Ibuprofen, mixer is stirred 15 minutes with the rotating speed of 80rpm at normal temperatures, and stirring sealing 4 hours and is filtered after terminating, and obtains the One mixed solution；
Step 2, streptomysin, pseudoephedrine, vitamin B1, vitamin C and glycerine are stirred, and are added while stirring Caffeine, caffeine is added after finishing, and mixer is stirred 30 minutes under 36 degrees Celsius with 180rpm, obtains the second mixing molten Liquid；
Step 3, honey, the first mixed solution and the second mixed solution are stirred and bottling is filtered, and are taken the photograph 150 Cooking disinfection is carried out under family name's degree, you can obtain finished product.
Embodiment 3
A kind of medicine for treating anemopyretic cold, is made up of following raw material according to weight portion：3 parts of Chai huang granule, sweet wormwood Element 2.5 parts, 4 parts of flavonols, 3 parts of brufen, 5 parts of streptomysin, 9 parts of pseudoephedrine, vitaminB10 .9 parts, 10 parts of vitamin C, 11 parts of honey, 13 parts of garlic juice, 6 parts of caffeine, 5 parts of glycerine and 28 parts of the ethanol solution that volume fraction is 65%.
The preparation method for treating the medicine of anemopyretic cold, comprises the following steps that：
Step one, to adding ethanol solution in garlic juice, then is added thereto to Chai huang granule, qinghaosu, flavonols and cloth Ibuprofen, mixer is stirred 22 minutes with the rotating speed of 110rpm at normal temperatures, and stirring is sealed 4 hours and filtered after terminating, and is obtained First mixed solution；
Step 2, streptomysin, pseudoephedrine, vitamin B1, vitamin C and glycerine are stirred, and are added while stirring Caffeine, caffeine is added after finishing, and mixer is stirred 35 minutes under 42 degrees Celsius with 210rpm, obtains the second mixing molten Liquid；
Step 3, honey, the first mixed solution and the second mixed solution are stirred and bottling is filtered, and are taken the photograph 180 Cooking disinfection is carried out under family name's degree, you can obtain finished product.
Embodiment 4
A kind of medicine for treating anemopyretic cold, is made up of following raw material according to weight portion：4 parts of Chai huang granule, sweet wormwood Element 3 parts, 5 parts of flavonols, 4 parts of brufen, 6 parts of streptomysin, 10 parts of pseudoephedrine, VB11 .5 parts, 12 parts of vitamin C, honeybee 12 parts of honey, 15 parts of garlic juice, 8 parts of caffeine, 6 parts of glycerine and 32 parts of the ethanol solution that volume fraction is 70%.
The preparation method for treating the medicine of anemopyretic cold, comprises the following steps that：
Step one, to adding ethanol solution in garlic juice, then is added thereto to Chai huang granule, qinghaosu, flavonols and cloth Ibuprofen, mixer is stirred 18 minutes with the rotating speed of 120rpm at normal temperatures, and stirring is sealed 4 hours and filtered after terminating, and is obtained First mixed solution；
Step 2, streptomysin, pseudoephedrine, vitamin B1, vitamin C and glycerine are stirred, and are added while stirring Caffeine, caffeine is added after finishing, and mixer is stirred 30 minutes under 45 degrees Celsius with 240rpm, obtains the second mixing molten Liquid；
Step 3, honey, the first mixed solution and the second mixed solution are stirred and bottling is filtered, and are taken the photograph 150 Cooking disinfection is carried out under family name's degree, you can obtain finished product.
500 patients of selection, men and women respectively accounts for half.500 patient's stochastic averaginas are divided into 5 groups and every group in sex and It is almost identical on age.Patient by the product of embodiment 1-4 to 1-4 groups takes, and existing product is taken to 5 groups of patients, often It three times, each 200ml and warm water delivery service is used, continue 3 days, therapeutic effect is shown in Table 1.Treatment standard：Cure：Various senses Emit symptom to be wholly absent, drug withdrawal is no longer recurred in one week；Effectively：Various cold symptoms substantially mitigate more than half；It is invalid：It is various Cold symptoms do not mitigate substantially, or even aggravate.
Table 1
As it can be seen from table 1 the cure rate of the product of embodiment 1-4 is more than 68%, significantly larger than existing product 43%；The effective percentage of the product of embodiment 1-4 more than 96%, significantly larger than the 64% of existing product, the product of embodiment 1-4 During patient's use, there is not any discomfort in patient.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie In the case of without departing substantially from spirit or essential attributes of the invention, the present invention can be in other specific forms realized.Therefore, no matter From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power Profit requires to be limited rather than described above, it is intended that all in the implication and scope of the equivalency of claim by falling Change is included in the present invention.
Moreover, it will be appreciated that although the present specification is described in terms of embodiments, not each implementation method is only wrapped Containing an independent technical scheme, this narrating mode of specification is only that for clarity, those skilled in the art should Specification an as entirety, the technical scheme in each embodiment can also be formed into those skilled in the art through appropriately combined May be appreciated other embodiment.

Claims (4)

1. a kind of medicine for treating anemopyretic cold, it is characterised in that be made up of according to weight portion following raw material：Chai huang granule 0.5-4 parts, qinghaosu 1-3 parts, flavonols 2-5 parts, brufen 0.5-4 parts, streptomysin 3-6 parts, pseudoephedrine 5-10 parts, dimension life Plain B10.1-1.5 parts, vitamin C 4-12 parts, honey 5-12 parts, garlic juice 5-15 parts, caffeine 3-8 parts, glycerine 2-6 parts and body Fraction is ethanol solution 15-32 part of 55-70%.
2. the medicine for treating anemopyretic cold according to claim 1, it is characterised in that by following raw material according to weight Part composition：Chai huang granule 2-4 parts, qinghaosu 1.5-3 parts, flavonols 3-5 parts, brufen 2-4 parts, streptomysin 4-6 parts, False path Alkali 7-10 parts, vitaminB10 .4-1.5 parts, vitamin C 7-12 parts, honey 7-12 parts, garlic juice 8-15 parts, caffeine 5-8 parts, Glycerine 3-6 parts and volume fraction are ethanol solution 21-32 parts of 55-70%.
3. the medicine for treating anemopyretic cold according to claim 1, it is characterised in that by following raw material according to weight Part composition：3 parts of Chai huang granule, 2.5 parts of qinghaosu, 4 parts of flavonols, 3 parts of brufen, 5 parts of streptomysin, 9 parts of pseudoephedrine, dimension life Plain B10.9 parts, 10 parts of vitamin C, 11 parts of honey, 13 parts of garlic juice, 6 parts of caffeine, 5 parts of glycerine and volume fraction are 55- 28 parts of 70% ethanol solution.
4. the preparation method of a kind of medicine for treating anemopyretic cold as described in claim 1-3 is any, it is characterised in that Comprise the following steps that：
Step one, to adding ethanol solution in garlic juice, then is added thereto to Chai huang granule, qinghaosu, flavonols and brufen, Mixer is stirred 15-25 minutes with the rotating speed of 60-120rpm at normal temperatures, and stirring is sealed 2-5 hours and filtered after terminating, and is obtained To the first mixed solution；
Step 2, streptomysin, pseudoephedrine, vitamin B1, vitamin C and glycerine are stirred, and coffee is added while stirring Cause, caffeine is added after finishing, and mixer is stirred 20-45 minutes under 30-45 degrees Celsius with 150-240rpm, is obtained second and is mixed Close solution；
Step 3, honey, the first mixed solution and the second mixed solution are stirred and bottling is filtered, and are taken the photograph in 100-200 Cooking disinfection is carried out under family name's degree, you can obtain finished product.
CN201611235906.7A 2016-12-28 2016-12-28 A kind of medicine for treating anemopyretic cold and preparation method thereof Pending CN106728752A (en)

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