CN106727923A - A kind of anti-bacteriostatic solution of Quaternary Ammonium Salt of Chitosan silver particles and preparation method thereof - Google Patents
A kind of anti-bacteriostatic solution of Quaternary Ammonium Salt of Chitosan silver particles and preparation method thereof Download PDFInfo
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Abstract
A kind of anti-bacteriostatic solution of Quaternary Ammonium Salt of Chitosan silver particles, the anti-bacteriostatic solution is by following components into being grouped into:Nano silver particles 5%~20%, Quaternary Ammonium Salt of Chitosan 0.5%~5%, ethanol 1%~3%, peppermint 0.1%~0.4%, remaining component is pure water.The beneficial effects of the invention are as follows, there is provided a kind of anti-bacteriostatic solution of Quaternary Ammonium Salt of Chitosan silver particles and preparation method thereof, anti-antibacterial effect, antibiotic rate > 99.99% can be effectively played.
Description
Technical field
The present invention relates to a kind of antiseptic solution, more particularly to a kind of anti-bacteriostatic solution of Quaternary Ammonium Salt of Chitosan silver particles and its system
Preparation Method.
Background technology
Be flooded with a large amount of bacteriums in life, silver be all since ancient times be verified with very strong antibacterial ability and have
The bactericidal effect of wide spectrum, Chinese patent CN101223887B proposes a kind of nano-silver antiseptic solution and preparation method, the original for using
Expect to be the nano silver particles and carboxymethyl chitosan of particle diameter 3nm~80nm, with antibacterial ability very high, its initial average antibacterial
Rate reaches 99.96%, and one annual antibiotic rate of storage reaches 90.35%, and sterilizing rate is lower slightly.
The content of the invention
It is an object of the present invention to provide a kind of anti-bacteriostatic solution of Quaternary Ammonium Salt of Chitosan silver particles, to solve the above problems.
Another object of the present invention is to, there is provided the preparation method of the above-mentioned anti-bacteriostatic solution of Quaternary Ammonium Salt of Chitosan silver particles.
The present invention is accomplished by the following way:
A kind of anti-bacteriostatic solution of Quaternary Ammonium Salt of Chitosan silver particles, the anti-bacteriostatic solution is by following components into being grouped into:Receive
Rice silver particles 5%~20%, Quaternary Ammonium Salt of Chitosan 0.5%~5%, ethanol 1%~3%, peppermint 0.1%~0.4%, remaining group
It is divided into pure water.
Further, the anti-bacteriostatic solution by following components into being grouped into:Nano silver particles 5%, Quaternary Ammonium Salt of Chitosan
1%, ethanol 2%, peppermint 0.1%, remaining component is pure water.
Further, a diameter of 2nm~20nm of the nano silver particles.
Further, the most preferred diameters of the nano silver particles are 2nm.
The preparation method of the above-mentioned anti-bacteriostatic solution of Quaternary Ammonium Salt of Chitosan silver particles, comprises the following steps:
S1:Dissolved at normal temperatures during Quaternary Ammonium Salt of Chitosan is added into pure water, and stood 10~14 hours;
S2:Nano silver particles are added into the mixed solution prepared by S1, suspension is made;
S3:Suspension prepared by S2 is stirred, mixing time 30 minutes is uniformly distributed nano silver particles, shape
Into the anti-bacteriostatic solution of Quaternary Ammonium Salt of Chitosan silver particles.
Further, the S1 stages Quaternary Ammonium Salt of Chitosan adds the optimal standing dissolved at normal temperatures in pure water
Time is 12 hours.
Core content of the invention is that Quaternary Ammonium Salt of Chitosan and silver particles are added in raw material, and Quaternary Ammonium Salt of Chitosan is with pure
Water purification leaching is molten 12 hours, is completely dissolved into liquid, and silver particles are extracted its silver from freshwater mussel pearl, are made into nanometer technology
Nanometer-level silver particle, add chitosan solution, the two mix after Cheng Kangyin solution.
Shitosan is lived as a kind of natural polymer with excellent biological functionality and compatibility with preferable antibacterial
Property, the growth and breeding of some fungies, bacterium and virus can be suppressed, chitosan gel rubber can add silver as the carrier of silver particles
Anti- bacteriostasis can be strengthened after particle.
According to the examining report at Guangzhou industrial microorganism center, the solution antibiotic rate > made by above-mentioned preparation method
99.99%.
The beneficial effects of the invention are as follows, there is provided a kind of anti-bacteriostatic solution of Quaternary Ammonium Salt of Chitosan silver particles and preparation method thereof,
Anti- antibacterial effect, antibiotic rate > 99.99% can be effectively played.
Specific embodiment
A kind of anti-bacteriostatic solution of Quaternary Ammonium Salt of Chitosan silver particles and preparation method thereof:
Its silver is extracted from freshwater mussel pearl, the nanometer-level silver particle that particle diameter is 2nm is made into nanometer technology, then adopt
Take following steps:
S1:Dissolved at normal temperatures during Quaternary Ammonium Salt of Chitosan is added into pure water, and stood 12 hours;
S2:Nano silver particles are added into the mixed solution prepared by S1, suspension is made;
S3:Suspension prepared by S2 is stirred, mixing time 30 minutes is uniformly distributed nano silver particles, shape
Into the anti-bacteriostatic solution of Quaternary Ammonium Salt of Chitosan silver particles.
According to the clinical data that concrete practice draws, during above-mentioned S1, in Quaternary Ammonium Salt of Chitosan addition pure water simultaneously
Dissolved at normal temperatures, be within 12 hours optimal, then sterilizing rate can slowly be declined dissolution time more than 12 hours, sterilizing rate is in line
Property downward trend.
Above-mentioned S2 and S3, adds nano silver particles and is stirred, and is in order that nano silver particles are uniformly distributed in dissolving
In Quaternary Ammonium Salt of Chitosan afterwards so that the anti-bacteriostatic solution ratio uniform made.
Claims (6)
1. a kind of anti-bacteriostatic solution of Quaternary Ammonium Salt of Chitosan silver particles, it is characterised in that:The anti-bacteriostatic solution by following components into
It is grouped into:Nano silver particles 5%~20%, Quaternary Ammonium Salt of Chitosan 0.5%~5%, ethanol 1%~3%, peppermint 0.1%~
0.4%, remaining component is pure water.
2. anti-bacteriostatic solution according to claim 1, it is characterised in that:The anti-bacteriostatic solution is by following components into packet
Into:Nano silver particles 5%, Quaternary Ammonium Salt of Chitosan 1%, ethanol 2%, peppermint 0.1%, remaining component is pure water.
3. anti-bacteriostatic solution according to claim 1 and 2, it is characterised in that:A diameter of 2nm of the nano silver particles~
20nm。
4. anti-bacteriostatic solution according to claim 3, it is characterised in that:The most preferred diameters of the nano silver particles are
2nm。
5. the preparation method of the anti-bacteriostatic solution of Quaternary Ammonium Salt of Chitosan silver particles described in a kind of claim 1, it is characterised in that:Bag
Include following steps:
S1:Dissolved at normal temperatures during Quaternary Ammonium Salt of Chitosan is added into pure water, and stood 10~14 hours;
S2:Nano silver particles are added into the mixed solution prepared by S1, suspension is made;
S3:Suspension prepared by S2 is stirred, mixing time 30 minutes is uniformly distributed nano silver particles, forms season
The anti-bacteriostatic solution of ammonium salt shitosan silver particles.
6. preparation method according to claim 5, it is characterised in that:The S1 stages Quaternary Ammonium Salt of Chitosan adds pure water
In the optimal time of repose that is dissolved at normal temperatures be 12 hours.
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107019002A (en) * | 2017-06-02 | 2017-08-08 | 兴化市恒威生物技术有限公司 | Culture of Chinese mitten crab pool-cleaning agent and preparation method thereof |
CN107258814A (en) * | 2017-07-11 | 2017-10-20 | 广东火云生态科技有限公司 | A kind of composite disinfectant of Quick disinfection sterilization and its preparation method and application |
CN110215534A (en) * | 2018-12-08 | 2019-09-10 | 普宁康特生物科技有限公司 | A kind of nanometer level pearl silver is medical to resist antibacterial gauze |
CN111995915A (en) * | 2020-08-11 | 2020-11-27 | 深圳市鼎元恒泰科技有限公司 | Water-soluble composite antibacterial coating and preparation method thereof |
CN112704088A (en) * | 2020-12-29 | 2021-04-27 | 南京启佑生物科技有限公司 | Special disinfectant for chopping board and preparation method and application thereof |
WO2021183041A1 (en) * | 2020-03-09 | 2021-09-16 | Kit Yew Cheng | The chemical composition for impregnation via spraying on disposable sugical masks, sleeves gowns made from hydrophilic and hydrophobic materials for the inactivation of bacteria and viruses such as coronavirus, sars, mers, influenza a and influenza b viruses |
CN114097825A (en) * | 2021-12-16 | 2022-03-01 | 山东大学 | Quaternized chitosan coated Ag-loaded CoP nanoneedle and preparation method thereof |
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107019002A (en) * | 2017-06-02 | 2017-08-08 | 兴化市恒威生物技术有限公司 | Culture of Chinese mitten crab pool-cleaning agent and preparation method thereof |
CN107258814A (en) * | 2017-07-11 | 2017-10-20 | 广东火云生态科技有限公司 | A kind of composite disinfectant of Quick disinfection sterilization and its preparation method and application |
CN110215534A (en) * | 2018-12-08 | 2019-09-10 | 普宁康特生物科技有限公司 | A kind of nanometer level pearl silver is medical to resist antibacterial gauze |
WO2021183041A1 (en) * | 2020-03-09 | 2021-09-16 | Kit Yew Cheng | The chemical composition for impregnation via spraying on disposable sugical masks, sleeves gowns made from hydrophilic and hydrophobic materials for the inactivation of bacteria and viruses such as coronavirus, sars, mers, influenza a and influenza b viruses |
CN111995915A (en) * | 2020-08-11 | 2020-11-27 | 深圳市鼎元恒泰科技有限公司 | Water-soluble composite antibacterial coating and preparation method thereof |
CN112704088A (en) * | 2020-12-29 | 2021-04-27 | 南京启佑生物科技有限公司 | Special disinfectant for chopping board and preparation method and application thereof |
CN114097825A (en) * | 2021-12-16 | 2022-03-01 | 山东大学 | Quaternized chitosan coated Ag-loaded CoP nanoneedle and preparation method thereof |
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