CN106727010A - A kind of special antibacterial film forming leaching hand liquid of milker - Google Patents
A kind of special antibacterial film forming leaching hand liquid of milker Download PDFInfo
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- CN106727010A CN106727010A CN201710006193.5A CN201710006193A CN106727010A CN 106727010 A CN106727010 A CN 106727010A CN 201710006193 A CN201710006193 A CN 201710006193A CN 106727010 A CN106727010 A CN 106727010A
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- Prior art keywords
- milker
- film forming
- hand liquid
- antibacterial film
- extract solution
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to a kind of special antibacterial film forming leaching hand liquid of milker, every kilogram of leaching hand liquid includes following components by weight percent：The 10g of chitosan oligosaccharide 5, the 10g of n-trimethyl chitosan chloride 5, the 300g of rosemary extract solution 200, the 80g of dandelion extract solution 50, the 5g of acetic acid 1, the 10g of glycerine 5, the 10g of emulsifying agent 5, the 5g of skin conditioner 1, balance of purified water.Chitosan oligosaccharide, n-trimethyl chitosan chloride, dandelion, rosemary are all organic-biological compositions, and most of pathogen that may be present to milking parlour to have preferably suppress kills effect.The present invention can form one layer of medicine film with n-trimethyl chitosan chloride as filmogen on both hands and forearm, can sustained anti-microbial protection, to milker operationally between interior energy form effectively protection, and the finger movement of milker is not interfered with, on work without influenceing.The medicine film that the special antibacterial film forming leaching hand liquid of milker of the invention is formed externally has protection antibacterial action, internally there is skin care moisture-keeping function, a kind of more preferable labour protection selection for milker.
Description
Technical field
The present invention relates to livestock breeding industry field of medicaments, more particularly to a kind of special antibacterial film forming leaching hand liquid of milker.
Background technology
Modern dairy cow farm is all to concentrate to milk using milking parlour, and general dairy cow farm is milked 2-3 times for one day, every time
Milk, working time of milker is more than 3 hours, repeatedly sterilize, paper handkerchief is blotted, a set of cups, take cup, dipping nipple it is dynamic
Make, work uninteresting and intensity is higher, and have directly contact with cow breast, emulsion, urine, saliva, excrement etc., sometimes
Waiting milk cow has wound, also therefore can considerably increase the infection probability of zoonosis with milk cow wound and contacting blood, although
Milker can put on mouth mask and avoid intrusion of the pathogen from mouth and nose, but hand and arm can not but be protected well, because
To have gloves on, operation is very inconvenient, can not the massaging breasts promotion milk-ejection reflex before milking well, a set of cups takes cup
Easily slip out of the hand, fine movement as dipping nipple is even more do bad, therefore most of milkers are all that light without gloves
Hand and arm are operated, but so cause milker to be exposed in high-risk environment.
Common at present is exactly directly left-hand seat operation after disinfecting in alcohol, but long-term very big to skin damage with alcohol,
And the alcohol disinfecting duration is not long, but milker one enters the milk Room, and work is exactly lasting more than 3 hours, not how many people
Can stop midway and carry out opponent and arm is sterilized again.So not only milker itself it is dangerous, and milker hand
It is also an approach for propagation pathogen from this ox to that ox.
The content of the invention
In order to solve problem above, the present invention proposes a kind of special antibacterial film forming leaching hand liquid of milker, it is intended to be milker
A kind of leaching hand articles for use for having antibacterial functions, energy film forming to protect are provided, for milk cattle cultivating enterprise provides a kind of preferably selection：
The special antibacterial film forming leaching hand liquid of milker of the invention, every kilogram of leaching hand liquid includes following components by weight percent：
Chitosan oligosaccharide 5-10g, n-trimethyl chitosan chloride 5-10g, rosemary extract solution 200-300g, dandelion extract solution 50-
80g, acetic acid 1-5g, glycerine 5-10g, emulsifying agent 5-10g, skin conditioner 1-5g, balance of purified water.
Further, the chitosan oligosaccharide molecular weight is less than 3000.
Further, the rosemary extract solution is the distillation stoste that fresh rosemary cauline leaf takes first 20 minutes after distillation.
Further, the dandelion extract solution is added water to cook 2 hours for dry dandelion leaf, is taken filtrate and is concentrated into 1ml phases
When in crude drug 1g.
Further, the emulsifying agent is OP-10, polysorbas20, ethoxylated alkyl sulfate, laureth sodium sulfovinate
In one or more.
Further, the skin conditioner be vitamin E, aloe in one or two.
The special antibacterial film forming of milker of the present invention soaks the preparation method of hand liquid, comprises the following steps：
(1) under the conditions of sterile purification room, load weighted chitosan oligosaccharide is mixed with medical purified water and obtains chitosan oligosaccharide
Solution, is then placed in load weighted n-trimethyl chitosan chloride, and being positioned over after stirring and dissolving in ultraviolet sterilizing cabinet carries out ultraviolet disinfection, goes out
Bacterium 15min；
(2) ultraviolet disinfecting is closed, to step 1) rosemary extract solution and dandelion extract solution are added in resulting solution, stir
Mix well mixed；Then acetic acid is added dropwise and adjusts mixed liquor pH value to 6.2-6.4；To addition glycerine, emulsifying agent, shield in mixed solution
Skin agent, accelerates stirring, ultraviolet disinfection 30min after stirring；
(3) finally mixed solution is dispensed according to product specification, after detection meets product standard, is packed,
It is made the special antibacterial film forming leaching hand liquid of milker.
Compared with prior art, the present invention has following gain effect：
1st, with chitosan oligosaccharide it is main antibacterial material in technical scheme, n-trimethyl chitosan chloride is main film forming
Material, dandelion extract solution, rosemary extract solution are auxiliary antibacterial material.Chitosan oligosaccharide, n-trimethyl chitosan chloride, dandelion, fan change
Perfume is all organic-biological composition, without any side effects, even if imprudence enters in milk in operation, also will not be to milk
Food security forms harmful effect.The organic anti-bacterial of the technical program increased the special antibacterial film forming leaching of milker into subassembly
The antibacterial range of hand liquid, to Escherichia coli, Salmonella, staphylococcus aureus, Pseudomonas aeruginosa, Liszt's monocyte hyperplasia
The life of bacterium, brief summary enteritis Yersinia, streptococcus, comma bacillus, shigella, Aerononas punctata category and some fungies etc.
It is long that there is preferably suppression killing action.
2nd, with n-trimethyl chitosan chloride as filmogen, chitosan oligosaccharide is anti-biotic material to the present invention.The film forming of shitosan and anti-
Bacterium property has been confirmed and widely uses in medical domain, and the chitosan anti-bacteria effect of different molecular weight is different, and molecular weight is low
Chitosan oligosaccharide antibacterial efficacy in 3000 is best, and shitosan filming performance is good, and n-trimethyl chitosan chloride under any circumstance can
Water is dissolved in, more conducively commercialization is used.Leaching hand liquid of the invention, it is only necessary to milker before the milk Room is entered, by both hands and small
In arm immersion leaching hand liquid, then take out again, one layer of medicine film will be formed at once on both hands and forearm.Shitosan is formed
Medicine film compare moistening and fit completely skin, it is different from the medicine film that polyvinyl alcohol is formed, obstruction will not be caused to the action of finger.
3rd, the leaching hand liquid of the technical program forms medicine film, energy sustained anti-microbial protection, to milker in work on hand and arm
The time interior energy of work is formed effectively to be protected, and does not interfere with the finger movement of milker, on work without influence.Work a period of time
If feeling medicine film on finger because operating friction causes thinning or missing, it is only necessary in placing into the technical program
It is stained with leaching hand liquid, every time in 3 hours of milking parlour work, both hands can be again stained with any time, to ensure work
Protected in time.
4th, the leaching hand liquid of the technical program does not have any side effect to skin, shitosan and rosemary extract solution to skin also
Play the role of to nourish and repair, in milker After Hours, rinsed with water to rinse out the film of formation, both hands and forearm dermal sensation
Moistening is flexible, and milker can be with long-term use.
5th, extensively, dandelion is common Chinese medicine material to the raw material sources in the technical program, cheap, and rosemary is Yunnan
The industrial crops of plantation, will monthly cradle for several times extensively, and fresh cauline leaf is dirt cheap, and be obtained by only need to simply distilling processing
Stoste must be distilled, therefore the leaching hand liquid of the technical program is with low cost, is suitable to large-scale dairy cow farm long-term use.
Specific embodiment
Embodiment 1
A kind of special antibacterial film forming leaching hand liquid of milker, every kilogram of leaching hand liquid includes following components by weight percent：
Chitosan oligosaccharide 10g, n-trimethyl chitosan chloride 10g, rosemary extract solution 300g, dandelion extract solution 80g, acetic acid 1-5g,
Glycerine 10g, emulsifying agent 10g, skin conditioner 5g, balance of purified water.
Further, the chitosan oligosaccharide molecular weight is less than 3000.
Further, the rosemary extract solution is the distillation stoste that fresh rosemary cauline leaf takes first 20 minutes after distillation.
Further, the dandelion extract solution is added water to cook 2 hours for dry dandelion leaf, is taken filtrate and is concentrated into 1ml phases
When in crude drug 1g.
Further, the emulsifying agent is OP-10.
Further, the skin conditioner is vitamin E and aloe.
The special antibacterial film forming of milker of the present invention soaks the preparation method of hand liquid, comprises the following steps：
(1) under the conditions of sterile purification room, load weighted chitosan oligosaccharide is mixed with medical purified water and obtains chitosan oligosaccharide
Solution, is then placed in load weighted n-trimethyl chitosan chloride, and being positioned over after stirring and dissolving in ultraviolet sterilizing cabinet carries out ultraviolet disinfection, goes out
Bacterium 15min；
(2) ultraviolet disinfecting is closed, to step 1) rosemary extract solution and dandelion extract solution are added in resulting solution, stir
Mix well mixed；Then acetic acid is added dropwise and adjusts mixed liquor pH value to 6.4；To addition glycerine, emulsifying agent, skin care in mixed solution
Agent, accelerates stirring, ultraviolet disinfection 30min after stirring；
(3) finally mixed solution is dispensed according to product specification, after detection meets product standard, is packed,
It is made the special antibacterial film forming leaching hand liquid of milker.
Embodiment 2
The special antibacterial film forming leaching hand liquid of milker of the invention, every kilogram of leaching hand liquid includes following components by weight percent：
Chitosan oligosaccharide 5g, n-trimethyl chitosan chloride 5g, rosemary extract solution 200g, dandelion extract solution 50g, acetic acid 1-5g are sweet
Oily 5g, emulsifying agent 5g, skin conditioner 1g, balance of purified water.
Further, the chitosan oligosaccharide molecular weight is less than 3000.
Further, the rosemary extract solution is the distillation stoste that fresh rosemary cauline leaf takes first 20 minutes after distillation.
Further, the dandelion extract solution is added water to cook 2 hours for dry dandelion leaf, is taken filtrate and is concentrated into 1ml phases
When in crude drug 1g.
Further, the emulsifying agent laureth sodium sulfovinate.
Further, the skin conditioner is vitamin E and aloe.
The special antibacterial film forming of milker of the present invention soaks the preparation method of hand liquid, comprises the following steps：
(1) under the conditions of sterile purification room, load weighted chitosan oligosaccharide is mixed with medical purified water and obtains chitosan oligosaccharide
Solution, is then placed in load weighted n-trimethyl chitosan chloride, and being positioned over after stirring and dissolving in ultraviolet sterilizing cabinet carries out ultraviolet disinfection, goes out
Bacterium 15min；
(2) ultraviolet disinfecting is closed, to step 1) rosemary extract solution and dandelion extract solution are added in resulting solution, stir
Mix well mixed；Then acetic acid is added dropwise and adjusts mixed liquor pH value to 6.2；To addition glycerine, emulsifying agent, skin care in mixed solution
Agent, accelerates stirring, ultraviolet disinfection 30min after stirring；
(3) finally mixed solution is dispensed according to product specification, after detection meets product standard, is packed,
It is made the special antibacterial film forming leaching hand liquid of milker.
Embodiment 3
By the special antibacterial film forming leaching hand liquid of milker prepared by embodiment 1 and embodiment 2, washed with alcohol conventional at present
Hand liquid is provided commonly for the milker of certain cattle farm, and experiment is divided into 3 groups, and 1 group is control group, and using alcohol hand cleanser, 2 groups is to make
Hand liquid is soaked with the special antibacterial film forming of milker prepared by embodiment 1,3 groups is that the milker prepared using embodiment 2 is special anti-
Bacterium film forming soaks hand liquid.Every group is used one week, and use feeling is made a report on by milker after each use, and result of the test is as follows：
Tested more than and can be seen that, the special antibacterial film forming of milker provided using the technical program soaks hand liquid, by
One layer of medicine film is formed on hand and arm, opponent and arm have protective action, it is to avoid the direct skin contact Contents in Cows of milker
Liquid, and the medicine film for being formed contains the antimicrobial components such as chitosan oligosaccharide, shitosan, dandelion, rosemary extract solution, because medicine film shape
Into rapid, operationally it is worn whenever feeling the medicine film on finger, finger is just stained with leaching hand liquid, medicine film one again at once
Directly have, therefore antibacterial action all exists within the whole working time；Chitosan oligosaccharide that the leaching hand liquid of the technical program is used, shell gather
Sugar and rosemary, inherently with skin-protecting function, though dandelion does not have other influences without obvious skin-protecting function to skin,
The skin conditioner of vitamin E and aloe is added again, therefore medicine film externally has protection antibacterial action on hand, internally there is skin care
Moisture-keeping function, a kind of more preferable labour protection selection for milker.
A kind of special antibacterial film forming leaching hand liquid of milker provided by the present invention is described in detail above.Lead to herein
Specific embodiment is crossed to be set forth principle of the invention and implementation method, it is described above to be only intended to help and understand this hair
Bright method and its core concept.It should be pointed out that for those skilled in the art, not departing from the present invention
On the premise of principle, some improvement and modification can also be carried out to the present invention, these are improved and modification also falls into right of the present invention
It is required that protection domain in.
Claims (7)
1. a kind of special antibacterial film forming of milker soaks hand liquid, it is characterized in that every kilogram of leaching hand liquid includes following components by weight percent：
Chitosan oligosaccharide 5-10g, n-trimethyl chitosan chloride 5-10g, rosemary extract solution 200-300g, dandelion extract solution 50-80g, second
Sour 1-5g, glycerine 5-10g, emulsifying agent 5-10g, skin conditioner 1-5g, balance of purified water.
2. the special antibacterial film forming of milker soaks hand liquid according to claim 1, it is characterised in that the chitosan oligosaccharide molecular weight is small
In 3000.
3. milker special antibacterial film forming leaching hand liquid according to claim 1, it is characterised in that the rosemary extract solution is
Fresh rosemary cauline leaf takes the distillation stoste of first 20 minutes after distillation.
4. milk cow nipple medicated bath liquid according to claim 1, it is characterised in that the dandelion extract solution is dry Folium Taraxacum
Son is added water to cook 2 hours, is taken filtrate and is concentrated into 1ml equivalent to crude drug 1g.
5. milker special antibacterial film forming leaching hand liquid according to claim 1, it is characterised in that the emulsifying agent be OP-10,
One or more in polysorbas20, ethoxylated alkyl sulfate, laureth sodium sulfovinate.
6. the special antibacterial film forming of milker soaks hand liquid according to claim 1, it is characterised in that the skin conditioner is vitamin
One or two in E, aloe.
7. a kind of special antibacterial film forming of milker soaks the preparation method of hand liquid, it is characterised in that comprise the following steps：
(1) under the conditions of sterile purification room, load weighted chitosan oligosaccharide is mixed with medical purified water and obtains chitosan oligosaccharide solution,
Load weighted n-trimethyl chitosan chloride is then placed in, being positioned over after stirring and dissolving in ultraviolet sterilizing cabinet carries out ultraviolet disinfection, sterilized
15min；
(2) ultraviolet disinfecting is closed, to step 1) rosemary extract solution and dandelion extract solution are added in resulting solution, stirring is mixed
Close uniform；Then acetic acid is added dropwise and adjusts mixed liquor pH value to 6.2-6.4；To addition glycerine, emulsifying agent, skin care in mixed solution
Agent, accelerates stirring, ultraviolet disinfection 30min after stirring；
(3) finally mixed solution is dispensed according to product specification, after detection meets product standard, is packed, be made
The special antibacterial film forming leaching hand liquid of milker.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710006193.5A CN106727010A (en) | 2017-01-05 | 2017-01-05 | A kind of special antibacterial film forming leaching hand liquid of milker |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710006193.5A CN106727010A (en) | 2017-01-05 | 2017-01-05 | A kind of special antibacterial film forming leaching hand liquid of milker |
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| Publication Number | Publication Date |
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| CN106727010A true CN106727010A (en) | 2017-05-31 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710006193.5A Withdrawn CN106727010A (en) | 2017-01-05 | 2017-01-05 | A kind of special antibacterial film forming leaching hand liquid of milker |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111227808A (en) * | 2020-03-25 | 2020-06-05 | 贵州中医药大学 | Palpation film spraying fingerstall, preparation method and device |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102604141A (en) * | 2012-02-29 | 2012-07-25 | 上海工程技术大学 | Method for preparing antibacterial film of quaternarized chitosan iodine complex |
| CN104546717A (en) * | 2015-01-27 | 2015-04-29 | 陈金和 | Highly-antibacterial chitosan film-forming agent and preparation method thereof |
| CN106234431A (en) * | 2016-07-27 | 2016-12-21 | 柳州创宇科技有限公司 | A kind of multi-functional plant source bactericide is for preventing and treating the purposes of Folium Hibisci pinta |
-
2017
- 2017-01-05 CN CN201710006193.5A patent/CN106727010A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102604141A (en) * | 2012-02-29 | 2012-07-25 | 上海工程技术大学 | Method for preparing antibacterial film of quaternarized chitosan iodine complex |
| CN104546717A (en) * | 2015-01-27 | 2015-04-29 | 陈金和 | Highly-antibacterial chitosan film-forming agent and preparation method thereof |
| CN106234431A (en) * | 2016-07-27 | 2016-12-21 | 柳州创宇科技有限公司 | A kind of multi-functional plant source bactericide is for preventing and treating the purposes of Folium Hibisci pinta |
Non-Patent Citations (2)
| Title |
|---|
| 侯春林等: "《几丁质与医学》", 31 May 2008, 上海科学技术出版社 * |
| 郑明学: "《兽医临床病理解剖学》", 31 August 2008, 中国农业大学出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111227808A (en) * | 2020-03-25 | 2020-06-05 | 贵州中医药大学 | Palpation film spraying fingerstall, preparation method and device |
| CN111227808B (en) * | 2020-03-25 | 2023-01-24 | 贵州中医药大学 | Palpation film spraying fingerstall, preparation method and device |
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