CN108014032A - A kind of hip pad wet tissue and preparation method thereof - Google Patents
A kind of hip pad wet tissue and preparation method thereof Download PDFInfo
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- CN108014032A CN108014032A CN201810001168.2A CN201810001168A CN108014032A CN 108014032 A CN108014032 A CN 108014032A CN 201810001168 A CN201810001168 A CN 201810001168A CN 108014032 A CN108014032 A CN 108014032A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0208—Tissues; Wipes; Patches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8105—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- A61K8/8111—Homopolymers or copolymers of aliphatic olefines, e.g. polyethylene, polyisobutene; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
- A61K2800/72—Hypo-allergenic
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Abstract
The present invention is suitable for nursing product technical field, there is provided a kind of hip pad wet tissue and preparation method thereof, hip pad wet tissue include wet tissue liquid and wet tissue carrier；The wet tissue liquid includes following component and the part by weight of each component is as follows:Emollient：0.2%~0.5%；Lysozyme：0.1%~0.5%；PH adjusting agent：0.3%~0.6%；Surplus is deionized water.The present invention is using pure natural, safe and non-toxic with the natural protective system of anti-inflammatory, antibacterial, antiviral lysozyme structure, not only favorable anti-corrosion effect, and gently non-stimulated to skin.
Description
Technical field
The invention belongs to nursing product technical field, more particularly to a kind of hip pad wet tissue and preparation method thereof.
Background technology
Due to wet tissue have skin care, sterilization and other effects and it is easy to carry, be widely used in the day of people
Often in life, for example, people with wet tissue come cleaning skin, wipe utensil etc..
Crowd or cleaning position are used for different, wet tissue can be divided into hip pad wet tissue, women wet tissue special, makeup removing specially
With wet tissue, household care wet tissue etc..However, hip pad wet tissue is exclusively used in cleaning-sterilizing buttocks, one in traditional hip pad wet tissue
As contain the sterilizing component such as alcohol.Research finds that the molecule of alcohol has very big penetrating power, can pass through skin table
The film in face is entered in Skin Cell, and long-time service contains the wet tissue of alcoholic content, is easy to cause skin and is followed the string, becomes
It is coarse, dry, or even the skin diseases such as allergy can be produced.
It can be seen from the above that existing hip pad wet tissue contain alcohol etc. easily make to become dry skin, it is coarse, follow the string, very
It is not high to the component for causing the skin diseases such as skin allergy, security.
The content of the invention
The embodiment of the present invention provides a kind of hip pad wet tissue, it is intended to solves existing hip pad wet tissue and contain alcohol etc. easily to make change
It must have dry skin, is coarse, following the string, or even causing the component of the skin diseases such as skin allergy, the problem of security is not high.
The embodiment of the present invention is achieved in that a kind of hip pad wet tissue, including wet tissue liquid and wet tissue carrier；The wet tissue liquid
Part by weight including following component and each component is as follows：Emollient：0.2%~0.5%；Lysozyme：0.1%~0.5%；pH
Conditioning agent：0.3%~0.6%；Surplus is deionized water.
Preferably, the wet tissue liquid includes following component and the part by weight of each component is：Emollient：0.2%；Bacteriolyze
Enzyme：0.2%；PH adjusting agent：0.6%；Surplus is deionized water.
Preferably, the wet tissue liquid includes following component and the part by weight of each component is：Emollient：0.2%~
0.5%；Lysozyme：0.1%~0.5%；PH adjusting agent：0.3%~0.6%；Skin conditioning agent：6%~10%；Solubilizer：
2%~5%；Fungicide：3.2%~7.1%；Surplus is deionized water.
Preferably, the wet tissue liquid includes following component and the part by weight of each component is：Emollient：0.2%；Bacteriolyze
Enzyme：0.5%；PH adjusting agent：0.6%；Skin conditioning agent：10%；Solubilizer：2%；Fungicide：3.2%；Surplus is deionization
Water.
Preferably, the wet tissue carrier be spunlace non-woven cloth, wet nonwoven fabrics, the one of which of needle punched non-woven fabrics or extremely
Composition two kinds few.
It is more highly preferred to, the wet tissue carrier is spunlace non-woven cloth.
Preferably, the emollient is caprylic/capric triglyceride, Parleam, neopentyl glycol dicaprylate/bis-
Mustard oil, thorn A Gan trees benevolence oil or oil are saved in decylate, isononyl isononanoate, jojoba seed oil, Butyrospermum parkii fruit fat, deep-sea two
The one of which of tea-seed oil or at least two mixture；
The pH adjusting agent is at least two mixing in citric acid, sodium citrate, boric acid, malic acid or sorbic acid
Thing.
Preferably, the skin conditioning agent is phytosterols oletate, bisabolol, isohexadecane, glycerine, β-Portugal gather
At least two mixture in sugar, dipotassium glycyrrhizinate, decoyl hydroximic acid or glycerol caprylate；
The solubilizer is rilanit special CO-40, maleic acid modified castor oil, castor-oil plant (RICINUS COMMUNIS) seed
The one of which or at least two mixture of oil, isopropanol either three isostearate of PEG-160 anhydrous sorbitols；
The fungicide is poly hexamethylene biguanide, tasteless L antiseptics, triclosan, tricyclazole or double ten alkyl-dimethyls
At least three kinds of mixture in ammonium chloride.
Preferably, the emollient includes following component and the part by weight of each component is：Water-soluble jojoba seed oil
0.2%；
The pH adjusting agent includes following component and the part by weight of each component is：Citric acid 0.1% and sodium citrate
0.5%；
The skin conditioning agent includes following component and the part by weight of each component is：Glycerine 8% and bisabolol 2%；
The solubilizer includes following component and the part by weight of each component is：Rilanit special CO-40 2%；
The fungicide includes following component and the part by weight of each component is：Tasteless L antiseptics 2%, polyhexamethylene
Biguanides 1% and didecyl Dimethy ammonium chloride 0.2%.
The embodiment of the present invention additionally provides the preparation method of above-mentioned hip pad wet tissue, includes the following steps：
Step 1：Formula according to above-mentioned wet tissue liquid weighs each component, spare.
Step 2：The part deionized water is added into ingredients pot, it is preferred that added into ingredients pot load weighted
60%~70% (percentage by weight) deionized water.
Step 3：The emollient is added in the ingredients pot, is heated to 50 DEG C~60 DEG C, it is preferred that be heated to 50
DEG C, and stir to being completely dissolved.
Step 4：It is to be cooled to be cooled to 20 DEG C~40 DEG C, it is preferred that when cooling to 30 DEG C, the lysozyme is added, and
Stir evenly.
Step 5：The pH adjusting agent is added, adjusts pH value to 5~6, it is preferred that adjusts pH value to 5.5, adds remaining
The deionized water, obtain the wet tissue liquid.
Step 6：By the wet tissue liquid with sterilizing after the wet tissue carrier according to part by weight be 3.3:1 is packaged.
Wherein, the sterilizing of wet tissue carrier preferably uses 121 DEG C, 30min moist heat sterilizations.
In above-mentioned hand mouth wet tissue the effect of each raw material and component is described as follows：
Caprylic/capric triglyceride：Viscosity is relatively low, can be as the base-material of moisturizing factor, it is easy to is absorbed by the skin, to changing
The uniform and smooth of cosmetic plays the role of good, makes skin lubrication glossy.
Parleam：It is colourless, odorless, tasteless, it is non-stimulated, completely harmless.Its sense of touch is soft, and no greasy feeling, has
Good moisturizing and moistening effect, the rapid skin permeation of energy, repairs skin elasticity, prevents invisible water loss；It is easily newborn at the same time
Change, stability is good, is widely used in baby care product.
Neopentyl glycol dicaprylate/dicaprate：For the side chain grease of cross structure, stability is good, and gas permeability is splendid,
With excellent skin-friendly.Not bellding light, skin sense is salubrious, silk is slided, and without glutinous soapy feeling, can also promote the absorption of active ingredient.
Isononyl isononanoate：With unique more methyl branch structures, sense as the silk cunning of grace is left to skin after use
By.
Jojoba seed oil (water solubility)：The grease of its molecules align and human body is closely similar, easily permeates human skin, inhales
The property received is good；Rich in abundant vitamin and protein in jojoba seed oil, hair quality moisture can be maintained, has and nourishes baby's skin
Health.
Butyrospermum parkii fruit fat：Be easy to absorb, rich in unrighted acid, the moisture-retaining capacity of skin can be strengthened, it is right
It can be moistened in the skin that dryness and cutin are damaged, and contain highest rate fat accompaniment, particularly grow necessary support
Triterpene alcohol and vitamin E, vitamin A, allantoin for dividing etc., can prevent skin water loss, help healing of wound, increase
Skin defence capability and compliance, are natural skin care ingredients.
Save mustard oil in deep-sea two：With good oxidation stability, skin sense silk is sliding, pleasant, rich in skin nutrition component.
Ci A does tree benevolence oil：It is a kind of Sapotaceae in the calcium carbonate semidesert mountain valley for growing the North African Area from western Mediterranean
The fruit of endemic species plant.Both edible can also be as cosmetic skincare product.Ci A does tree benevolence oil containing abundant vitamin E
And unrighted acid, alpha-tocopherol etc., skin can be protected to resist external stimulus, strengthen skin immune system function, improve god
The problems such as percutaneous moss；Oxidation resistance is extremely strong, has good maintenance effect to sensitiveness skin.
Camellia seed oil：Containing vitamin E and antioxidant content, therefore it can protect skin, can especially prevent skin injury
And aging, make skin that there is gloss.
Lysozyme：It is a kind of alkaline enzyme that can be hydrolyzed and polysaccharide is sticked in pathogenic bacteria.Mainly by destroying the N- second in cell membrane
β-Isosorbide-5-Nitrae glycosidic bond between acyl muramic acid and n-acetylglucosamine, makes the insoluble glutinous polysaccharide of cell membrane resolve into soluble sugar
Peptide, causes cell wall rupture content to escape and make bacterolysis.Lysozyme can also directly be tied with negatively charged virus protein
Close, form double salt with DNA, RNA, apoprotein, make virally inactivated.Therefore, which there is antibacterial, anti-inflammatory, antiviral etc. to make
With, and it is safe.Lysozyme is a kind of native protein, and property is very stable.
Citric acid：Belong to one kind of tartaric acid, available for buffer solution is prepared, adjust pH, cutin renewal can be accelerated, be usually used in
Lotion, creams etc..
Sodium citrate：Accelerate cutin renewal, be usually used in lotion, shampoo, whitening articles for use, anti-aging articles for use, Spot
Product etc..The renewal of cutin contributes to the peeling of the melanin of skin, and the receipts of pore are thin, dissolving of blackhead etc..
Boric acid：Its aqueous solution is in faintly acid, can be used as pH adjusting agent.
Malic acid：It is present in the fruits such as jejune apple, grape, hawthorn, also can be by fumaric acid through biofermentation
It is made, has special happy, soft tart flavour, pH value can be reduced, skin surface wrinkle can be removed, skin is become tender white, light
It is clean and flexible, there is antibacterial and oxidation resistant effect.
Sorbic acid：Sorbic acid can effectively inhibit the activity of mould, saccharomycete and aerobic bacteria, so as to reach effectively
Extend the holding time of food.Sorbic acid (potassium) belongs to acid preservative, still have in the food close to neutral (PH6.0-6.5) compared with
Good antisepsis.
Phytosterols oletate：There is very high permeability to skin, skin surface moisture content can be kept, promote skin new
It is old metabolism, suppress scytitis, can anti-sunburn, skin aging, also have hair tonic, hair care the effect of.For the production of cream,
There is use feeling good (auxiliary malleability good, smooth do not glue), durability is good, is unlikely to deteriorate.
Bisabolol：It is mainly used in skin sparing and nursing cosmetics, its stability is good, and absorbability is strong, has and relaxes
Slow skin, anti-inflammatory, antiallergy, anti-irritant and bacteriostasis.
Isohexadecane：Have no toxic side effect, non-stimulated no sensitization, security is good, excellent performance.Its skin sense is more preferably salubrious,
Gracefulness, can be greatly reduced the greasy feeling of cream and product emulsion.
Glycerine：With stronger hygroscopicity, skin moisture-keeping is moistened, be common softening agent, viscosity in cosmetics manufacture
Modifier and solvent.
Beta glucan：As the active ingredient of cosmetics, resisting skin allergy ability can be improved, immune function is activated, prolongs
Slow skin senescence.Fine wrinkles can be smoothed, improve skin elasticity, improve dermatoglyph degree；With unique straight chain molecule knot
Structure, imparts good Transdermal absorption performance；Promote fibroblast synthesis collagen, promote wound healing, repair impaired
Skin, gives skin and smooth sense of touch is moistened such as silk.
Dipotassium glycyrrhizinate：Corticosteroid compound (suppression metabolic enzyme) can be activated, indirectly strengthens corticosteroid compound
Effect, all cosmetics such as cream, frost, water, dew, lotion, milk and sweet class can be used in, it can in and/or release or subtract
The noxious material of low cosmetics, the allergic reaction for the cosmetics being also possible to prevent, is more suitable for advanced hair or skin makeup
In product.
Decoyl hydroximic acid：Property is gentle, non-stimulated to skin, to inhibiting bacteria and the effect of fungi (containing mould) is fabulous.
Glycerol caprylate：For 100% natural material, by ECOCERT Organic certifications, it is a kind of Multifunctional protective humectant, adds
Fat agent, to skin-friendly, has potent antibacterial activity.
Rilanit special CO-40：For a kind of excellent nonionic solubilizer and emulsifying agent, many natural and chemistry can be made
Organic oil-soluble ingredients of synthesis dissolve to form stablizing solution in water, and do not change the property and smell of material, improve product
With function, performance and sense organ.With its unique attraction, it is possible to reduce or the organic solvent in elimination product, it is possible to reduce
The detrimental effect of organic solvent and influence, while make that product fragrance is purer, feels more natural.Rilanit special CO-40 safety
Property is high, does not have any irritation and anaphylaxis to skin, to skin feel it is submissive, smooth, without sticky sense.
Maleic acid modified castor oil：There is splendid compatibility with skin, while be not easy to be washed away by surfactant, especially exist
It is particularly useful in flushing cleaning products, moisture can be kept.Maleic acid modified castor oil can be with ceramide in keratoderma
Orderly lipid conformation is formed with the same mode of action of sterol and aliphatic acid, can also be acted as jointly with natural skin liposome
With reparation and the barrier function for strengthening skin.
Castor-oil plant (RICINUS COMMUNIS) seed oil：With good stability, colour retention, pliability, pigment-dispersing, profit
Moist, lubricity agent biological nature.
Isopropanol：Dissolution is played in cosmetics, can be used for dissolving other components, make product that there is certain property
Energy and formulation.
Three isostearate of PEG-160 anhydrous sorbitols：The chemistry of hydrophilic emulsifying agent and dispersant for aromatics
Product and grease type have solubilization.Excellent hydrophilic emulsifying agent as, series can and thermophilic emulsifier combine and produce good water oil
Balance.
Poly hexamethylene biguanide：It is widely used in the fields such as health care, household chemicals, papermaking, wet tissue, cultivation, uses
Make disinfectant, antiseptic, bactericidal agent, mould proof (corruption) agent, algicide.Killed with wide spectrum and suppress multiple-microorganism, bacterium effect
Persistently, bacterium is not likely to produce the resistance to the action of a drug；Actual nontoxic level is detected as to human body and higher mammal, it is non-stimulated to skin and mucous membrane
Property.
Tasteless L antiseptics, didecyl Dimethy ammonium chloride：It is respectively provided with excellent bactericidal and bacteriostatic effect.
Triclosan：It is cloudy to Gram positive bacteria, Gram for the safe antibiosis and sterilization agent of external application broad-spectrum high efficacy of international popular
Property sclerotium mould and saccharomycete have stronger inhibitory or killing effect.
Tricyclazole：It is prevention rice blast bactericide specially, belongs to thiazoles.Bactericidal effect mechanism mainly suppresses attachment spore
The formation of melanin, forms so as to suppress spore germination and attachment spore, prevents germ from invading people and reduce the production of magnaporthe grisea spore
It is raw.
Spunlace non-woven cloth：With excellent pliability, moistening permeability and fracture strength.
Wet nonwoven fabrics：Weak, high-strength, ventilative, acid and alkali-resistance, be stale-proof, be not mould, not eating into, nonpoisonous and tasteless, stingless to skin
Swash.
Needle punched non-woven fabrics：Generally thicker, for grammes per square metre generally more than 80 grams, fiber is thicker, and feel is rougher, and surface has carefully
Small pin hole, health it is medical, it is hygienic use, it is cosmetically relatively broad.
Hip pad wet tissue provided in an embodiment of the present invention, which does not contain alcohol etc., easily makes skin become dry, coarse, lose bullet
Property, or even cause the component of the skin diseases such as skin allergy, but use it is pure natural, there is anti-inflammatory, is antibacterial, antiviral molten
Bacterium enzyme builds natural antisepsis and sterilization system, is not only able to effectively anti-corrosion, and gently non-stimulated to skin, safe and non-toxic.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, below in conjunction with specific embodiment, to this
Invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, not
For limiting the present invention.
The embodiment of the present invention provide hip pad wet tissue using it is pure natural, there is anti-inflammatory, antibacterial, antiviral lysozyme structure
Natural protective system, not only favorable anti-corrosion effect, and gently non-stimulated to skin are safe and non-toxic.
Technical scheme and technique effect are described further below by way of specific embodiment.
Embodiment 1：
The wet tissue formula of liquid of hip pad wet tissue：By weight, the part by weight of each component in formula and each component is as follows：Profit
Skin agent (water-soluble jojoba seed oil 0.3%)；Lysozyme 0.1%；PH adjusting agent (citric acid 0.1%, sodium citrate 0.3%),
Totally 0.4%；Skin conditioning agent (bisabolol 1%, glycerine 5%), totally 6%；Solubilizer (rilanit special CO-40 4%)；Kill
Microbial inoculum (poly hexamethylene biguanide 2%, tasteless L antiseptics 2%, didecyl Dimethy ammonium chloride 0.1%), totally 4.1%；Surplus
For deionized water.
In an embodiment of the present invention, the preparation method of hip pad wet tissue includes the following steps：
Step 1：Formula according to above-mentioned wet tissue liquid weighs each component, spare.
Step 2：Portions of de-ionized water is added into ingredients pot, it is preferred that add load weighted 60% into ingredients pot~
70% (percentage by weight) deionized water.
Step 3：Emollient, skin conditioning agent, solubilizer are added in ingredients pot, are heated to 50 DEG C~60 DEG C, preferably
, it is heated to 50 DEG C, and stir to being completely dissolved.
Step 4：It is to be cooled to be cooled to 20 DEG C~40 DEG C, it is preferred that when cooling to 30 DEG C, to add lysozyme, sterilization
Agent, and stir evenly.
Step 5：PH adjusting agent is added, adjusts pH value to 5~6, it is preferred that adjusts pH value to 5.5, adds remaining go
Ionized water, obtains wet tissue liquid.
Step 6：By wet tissue liquid with sterilizing after wet tissue carrier according to part by weight be 3.3:1 is packaged.Wherein, it is wet
The sterilizing of towel carrier preferably uses 121 DEG C, 30min moist heat sterilizations, and operation is packaged under sterile environment.Preferably,
Wet tissue carrier is spunlace non-woven cloth.
Embodiment 2：
The wet tissue formula of liquid of hip pad wet tissue：By weight, the part by weight of each component in formula and each component is as follows：Profit
Skin agent (water-soluble jojoba seed oil 0.2%)；Lysozyme 0.2%；PH adjusting agent (citric acid 0.1%, sodium citrate 0.5%),
Totally 0.6%；Skin conditioning agent (bisabolol 2%, glycerine 8%), totally 10%；Solubilizer (rilanit special CO-40 2%)；Kill
Microbial inoculum (poly hexamethylene biguanide 1%, tasteless L antiseptics 2%, didecyl Dimethy ammonium chloride 0.2%), totally 3.2%；Surplus
For deionized water.
In an embodiment of the present invention, the preparation method of hip pad wet tissue is identical with embodiment 1.
Embodiment 3：
The wet tissue formula of liquid of hip pad wet tissue：By weight, the part by weight of each component in formula and each component is as follows：Profit
Skin agent (water-soluble jojoba seed oil 0.5%)；Lysozyme 0.5%；PH adjusting agent (citric acid 0.1%, sodium citrate 0.5%),
Totally 0.6%；Skin conditioning agent (bisabolol 5%, glycerine 5%), totally 10%；Solubilizer (rilanit special CO-40 4%)；Kill
Microbial inoculum (poly hexamethylene biguanide 1%, tasteless L antiseptics 5%, didecyl Dimethy ammonium chloride 0.1%), totally 6.1%；Surplus
For deionized water.
In an embodiment of the present invention, the preparation method of hip pad wet tissue is identical with embodiment 1.
Embodiment 4：
The wet tissue formula of liquid of hip pad wet tissue：By weight, the part by weight of each component in formula and each component is as follows：Profit
Skin agent (water-soluble jojoba seed oil 0.2%)；Lysozyme 0.2%；PH adjusting agent (citric acid 0.1%, sodium citrate 0.3%),
Totally 0.4%；Skin conditioning agent (bisabolol 2%, glycerine 5%), totally 7%；Solubilizer (rilanit special CO-40 2%)；Kill
Microbial inoculum (poly hexamethylene biguanide 2%, tasteless L antiseptics 5%, didecyl Dimethy ammonium chloride 0.1%), totally 7.1%；Surplus
For deionized water.
In an embodiment of the present invention, the preparation method of hip pad wet tissue is identical with embodiment 1.
Embodiment 5：
The wet tissue formula of liquid of hip pad wet tissue：By weight, the part by weight of each component in formula and each component is as follows：Profit
Skin agent (water-soluble jojoba seed oil 0.3%)；Lysozyme 0.1%；PH adjusting agent (citric acid 0.1%, sodium citrate 0.2%),
Totally 0.3%；Skin conditioning agent (bisabolol 1%, glycerine 8%), totally 9%；Solubilizer (rilanit special CO-40 5%)；Kill
Microbial inoculum (poly hexamethylene biguanide 2%, tasteless L antiseptics 2%, didecyl Dimethy ammonium chloride 0.2%), totally 4.2%；Surplus
For deionized water.
In an embodiment of the present invention, the preparation method of hip pad wet tissue is identical with embodiment 1.
Embodiment 6：
The wet tissue formula of liquid of hip pad wet tissue：By weight, the part by weight of each component in formula and each component is as follows：Profit
Skin agent (water-soluble jojoba seed oil 0.2%, deep-sea two save mustard oil 0.1%), totally 0.3%；Lysozyme 0.4%；PH adjusting agent
(citric acid 0.1%, sorbic acid 0.25%), totally 0.35%；Skin conditioning agent (phytosterols oletate 3%, glycerine 4%, radix glycyrrhizae
Sour dipotassium 3%), totally 10%；Solubilizer (rilanit special CO-40 3%, castor-oil plant (RICINUS COMMUNIS) seed oil 2%),
Totally 5%；Fungicide (poly hexamethylene biguanide 1.5%, triclosan 1.5%, tricyclazole 1%), totally 4%；Surplus is deionized water.
In an embodiment of the present invention, the preparation method of hip pad wet tissue is same as Example 1.
Embodiment 7：
The wet tissue formula of liquid of hip pad wet tissue：By weight, the part by weight of each component in formula and each component is as follows：Profit
Skin agent (water-soluble jojoba seed oil 0.1%, Butyrospermum parkii fruit fat 0.1%), totally 0.2%；Lysozyme 0.2%；PH adjusting agent (lemon
Lemon acid 0.15%, sodium citrate 0.45%), totally 0.6%；Surplus is deionized water.
In an embodiment of the present invention, the preparation method of hip pad wet tissue is substantially the same manner as Example 1, and difference is to walk
Rapid three：Emollient is added in the ingredients pot, is heated to 50 DEG C~60 DEG C, it is preferred that is heated to 50 DEG C, and stirs to complete
Dissolving.Step 4：It is to be cooled to be cooled to 20 DEG C~40 DEG C, it is preferred that when cooling to 30 DEG C, to add lysozyme, and stir equal
It is even.
Embodiment 8：
The wet tissue formula of liquid of hip pad wet tissue：By weight, the part by weight of each component in formula and each component is as follows：Profit
Skin agent (caprylic/capric triglyceride 0.1%, Parleam 0.05%, water-soluble jojoba seed oil 0.1%), altogether
0.25%；Lysozyme 0.5%；PH adjusting agent (sodium citrate 0.3%, boric acid 0.1%), totally 0.4%；Surplus is deionized water.
In embodiments of the present invention, the preparation method of hip pad wet tissue is same as Example 7.
Embodiment 9：
The wet tissue formula of liquid of hip pad wet tissue：By weight, the part by weight of each component in formula and each component is as follows：Profit
Skin agent (neopentyl glycol dicaprylate/dicaprate 0.05%, isononyl isononanoate 0.15%, water-soluble jojoba seed oil
0.2%th, mustard oil 0.1% is saved at deep-sea two), totally 0.5%；Lysozyme 0.2%；PH adjusting agent (sodium citrate 0.2%, malic acid
0.1%), totally 0.3%；Surplus is deionized water.
In embodiments of the present invention, the preparation method of hip pad wet tissue is same as Example 7.
Embodiment 10：
The wet tissue formula of liquid of hip pad wet tissue：By weight, the part by weight of each component in formula and each component is as follows：Profit
Skin agent (water-soluble jojoba seed oil 0.1%, thorn A Gan tree benevolence oil 0.05%, camellia seed oil 0.05%), totally 0.2%；Lysozyme
0.1%；PH adjusting agent (citric acid 0.1%, sodium citrate 0.2%, boric acid 0.05%, malic acid 0.05%, sorbic acid
0.2%), totally 0.6%；Surplus is deionized water.
In an embodiment of the present invention, the preparation method of hip pad wet tissue is same as Example 7.
Embodiment 11：
The wet tissue formula of liquid of hip pad wet tissue：By weight, the part by weight of each component in formula and each component is as follows：Profit
Skin agent (caprylic/capric triglyceride 0.06%, Parleam 0.05%, neopentyl glycol dicaprylate/dicaprate
0.08%th, isononyl isononanoate 0.02%, water-soluble jojoba seed oil 0.05%, Butyrospermum parkii fruit fat 0.05%, deep-sea two are saved
Mustard oil 0.05%, thorn A Gan tree benevolence oil 0.04%, camellia seed oil 0.05%), totally 0.45%；Lysozyme 0.35%；PH is adjusted
Agent (citric acid 0.12%, sodium citrate 0.28%, sorbic acid 0.1%), totally 0.5%；Surplus is deionized water.
In an embodiment of the present invention, the preparation method of hip pad wet tissue is same as Example 7.
It should be noted that in an embodiment of the present invention, emollient is caprylic/capric triglyceride, the poly- isobutyl of hydrogenation
Mustard is saved at alkene, neopentyl glycol dicaprylate/dicaprate, isononyl isononanoate, jojoba seed oil, Butyrospermum parkii fruit fat, deep-sea two
Seed oil, thorn A Gan trees the benevolence oily either one of which of camellia seed oil or at least two mixture.For convenience of description, it is above-mentioned
Illustrate only several preferred compositions modes therein in embodiment, in actual application, can arbitrarily select it is therein a kind of or
At least two material of person carries out mixing compounding, as long as keeping the material of selection percentage by weight shared in the formula of wet tissue liquid
For 0.2%~0.5%, one of the various combinations are not just enumerated herein.
Based on it is above-mentioned identical the reasons why, pH adjusting agent involved by the embodiment of the present invention is citric acid, sodium citrate, boron
At least two mixture in acid, malic acid or sorbic acid；Skin conditioning agent for phytosterols oletate, bisabolol,
At least two mixing in isohexadecane, glycerine, beta glucan, dipotassium glycyrrhizinate, decoyl hydroximic acid or glycerol caprylate
Thing；Solubilizer is rilanit special CO-40, maleic acid modified castor oil, castor-oil plant (RICINUS COMMUNIS) seed oil, isopropanol
The either one of which or at least two mixture of three isostearate of PEG-160 anhydrous sorbitols；Fungicide is poly- six
At least three kinds mixed in methylene biguanides, tasteless L antiseptics, triclosan, tricyclazole or didecyl Dimethy ammonium chloride
Compound.Each compounded combination mode of these above-mentioned components is not also enumerated herein one by one.
In order to further illustrate the security and using effect of hip pad wet tissue provided in an embodiment of the present invention, below by way of tool
The test example of body further illustrates the beneficial effect of hip pad wet tissue provided in an embodiment of the present invention：
Experiment one：Safe and healthy detection
1st, test specimen：Hip pad wet tissue sample provided in an embodiment of the present invention.
2nd, test method：Sanitary index GB15979-2002《Disposable Sanitary Accessory sanitary standard》.
3rd, result of the test, refers to table 1 below.
Table 1
| Inspection project | Unit | Inspection result | Standard requirement | Conclusion |
| Total number of bacterial colonies | CFU/g | ＜ 20 | ≤200 | Meet |
| Fungus colony sum | CFU/g | ＜ 20 | ≤100 | Meet |
| Coliform | / | Do not detect | It must not detect | Meet |
| Staphylococcus aureus | / | Do not detect | It must not detect | Meet |
| Pseudomonas aeruginosa | / | Do not detect | It must not detect | Meet |
| Hemolytic streptococcus | / | Do not detect | It must not detect | Meet |
As can be seen that the microorganism detection of hip pad wet tissue provided in an embodiment of the present invention refers to from the result of the test of upper table 1
Mark meets GB15979-2002《Disposable Sanitary Accessory sanitary standard》Requirement, wholesomeness is good.
Experiment two：Acute oral toxicity test
1st, the preparation of experimental liquid：25 grams of wet tissue liquid sample for weighing the hip pad wet tissue of the offer of embodiment 1~11 respectively is extremely compiled
Number 100mL is settled in the volumetric flask of No. 1-11, to add ultra-pure water, mixing is used as experimental liquid.
2nd, trial test：Oral gavage experiment is carried out to experimental animal using the experimental liquid of 5000mg/kg body weight doses, is not sent out
There is death in existing experimental animal, therefore formal test design dosage is 5000mg/kg weight.
3rd, formal test：120 healthy, 18~20 grams of weight SPF level kunming mices are chosen, stochastic averagina is divided into 12
Group, every group each 10, half male and half female, and it is 1~12 to number, wherein, group 1 is blank control group, by the amount of 0.2mL/10g weight
Ultra-pure water is given with oral 1 gavage of gastric perfusion needle；Group 2~groups 12 are respectively by oral 1 time of the amount gastric perfusion needle of 0.2mL/10g weight
Gavage gives 1~No. 11 experimental liquid, that is, organizes 2 and give No. 1 experimental liquid, group 3 gives No. 2 experimental liquids, and group 4 gives No. 3 experimental liquids, group
5 give No. 4 experimental liquids ..., and group 12 gives No. 11 experimental liquids.When each group animal fasting 16 is small before gavage, freely drink
Water, gives normal diet, Routine Management after gavage；In 22 DEG C ± 1 DEG C of room temperature, raised in the environment of humidity 60% ± 5% identical
Number of days, the poisoning symptom and death condition for observing mouse daily simultaneously record, after the completion of experiment in 14 days, to result of the test into line number
According to statistics.
Wherein, during this experiment, it is poisoned during finger to finger test, mouse occurs trembling, twitches, salivates, diarrhea, drowsiness
Or the symptom such as stupor.Oral toxicity classification is as shown in table 2 below：
Table 2
| LD50(mg/Kg) | ≤50 | 51~500 | 501~5000 | ＞ 5000 |
| Toxicity grading | High poison | Medium poison | Low toxicity | It is actual nontoxic |
During whole experiment, the diet activity of each group animal subject is normal, has no obvious poisoning symptom and death.Cause
This, its mouse oral acute toxicity LD50 of the wet tissue liquid of hip pad wet tissue provided in an embodiment of the present invention>5000mg/kg weight, can
See that its security is good.
Experiment three：Preservative efficacy testing
1st, test specimen：Hip pad wet tissue sample provided in an embodiment of the present invention；Experimental bacteria for Escherichia coli ATCC 25922,
Staphylococcus aureus ATCC 6538, pseudomonas aeruginosa ATCC 9027, Candida albicans ATCC 10231.
2nd, test method：Microbiology challenge test method.
3rd, result evaluation：Using《European Pharmacopoeia》Result evaluation standard this result of the test is evaluated, have
Body refers to table 2 below.
Table 3
It was found from the test result of upper table 3,4 kinds of experimental bacterias (1 week) total plate count when the 7th day declines 100%, to
Without growth at 28 days, judge to test by challenge, inhibitor effectiveness is good, i.e., hip pad wet tissue liquid provided in an embodiment of the present invention
Anti-corrosion effect is good.
Experiment four：Skin irritation test
(1) skin closure type patch test
1st, test specimen：The wet tissue liquid of hip pad wet tissue provided in an embodiment of the present invention.
2nd, test method：From a certain 36 volunteers of regional choice, the age of volunteer, body was good between 20~45 years old
Health, in the recent period non-drug administration, nonbreast-fed women or gravid woman, non-constitution sensitive subjects.Volunteer is divided into 12 groups at random,
Every group of three people.Wherein, group 1 is blank control group, and the small interior of spot examination device does not place any material, spot is tried the low sensitization glue of device
Band is pasted on the back of volunteer or forearm bends side, is gently pressed with palm and is allowed to equably stick on the skin；Group 2~groups 12 with
The processing method of group 1 is identical, unlike：The wet tissue liquid provided added with the 0.025mL embodiment of the present invention 1~11 is put into respectively
The small interior of spot examination device；I.e. group 2 it is corresponding be the embodiment of the present invention 1 provide wet tissue liquid, group 3 it is corresponding be the embodiment of the present invention 2
The wet tissue liquid of offer, it is wet tissue liquid ... that the embodiment of the present invention 3 provides that group 4 is corresponding, and corresponding group 12 is this
The wet tissue liquid that inventive embodiments 11 provide.When each group test duration 24 is small, 48 it is small when after, remove spot examination device after 30min, treat impression
After disappearance, observation sticks the response situation and record of place's skin.
Wherein, skin closure type patch test dermoreaction grade scale see the table below 4.
Table 4
During whole experiment, the subject's of group 1- groups 12 is reacted negative by gesture area skin.Thus
As can be seen that the wet tissue liquid of hip pad wet tissue provided in an embodiment of the present invention will not cause the allergy and stimulate the reaction of skin, safety
Property is good.
(2) repeatability is opening smears experiment
1st, test specimen：Hip pad wet tissue sample provided in an embodiment of the present invention.
2nd, from a certain region select 36 volunteers, the age of volunteer between 20-45 Sui, health, in the recent period
Non- drug administration, nonbreast-fed women or gravid woman, non-constitution sensitive subjects.Volunteer is divided into 12 groups, every group three at random
It is personal.Wherein, group 1 is blank control group, is bent using forearm and is used as recipient site, 3 × 3cm of area2, recipient site holding drying,
Avoid contact with before tested and during by gesture other external preparations, with ultra-pure water 0.05 ± 0.005g/ times, equably smear tested portion
Position；Group 2~groups 12 are respectively test group, unlike group 1：The hip pad wet tissue provided using the embodiment of the present invention 1~11
Wet tissue liquid equably smears recipient site 0.05 ± 0.005g/ times；Wherein, it is wet to correspond to the hip pad that the embodiment of the present invention 1 provides for group 2
The wet tissue liquid of towel, group 3 correspond to the wet tissue liquid for the hip pad wet tissue that the embodiment of the present invention 2 provides, and the correspondence embodiment of the present invention 3 of group 4 carries
The wet tissue liquid ... of the hip pad wet tissue of confession and so on, group 12 corresponds to the wet tissue for the hip pad wet tissue that the embodiment of the present invention 11 provides
Liquid.Each group carries out equably smearing recipient site for 2 times daily, and long run test completes experiment after 7 days, daily observation subject by
Try the dermoreaction situation at position and record.It is anti-if there is more than 3 points of skin in such as table 5 below during experiment
When answering situation, it can stop continuing to test and record result.
Wherein, table 5 smears experiment dermoreaction judgment criteria table for skin repeatability is opening.
Table 5
During whole experiment, the dermoreaction by gesture position of the subject of group 1~groups 12 is negative.By
This, which can be seen that hip pad wet tissue provided in an embodiment of the present invention, will not cause the allergy and stimulate the reaction of skin, and security is good.
Experiment five：Using effect is tested
(1) moistening effect is tested
1st, test specimen：Hip pad wet tissue and contrast product provided in an embodiment of the present invention are wonderful to think happy pleasant baby wipes
(France), shellfish parent baby wipes (Japan), warm breathe out that baby cleans wet paper handkerchief (China), Kang Ying is good for baby wipes (China).
2nd, test method：A certain region, subject 75 people of the age at 18~25 years old are randomly selected, and stochastic averagina is divided into
15 groups, every group of 5 people, numbering 1~15, wherein, group 1~groups 4 are control group 1~groups 4, are respectively wonderful to think happy pleasant baby wipes
(France) test control group 1, shellfish parent baby wipes (Japan) test control group 2, warm baby's cleaning wet paper handkerchief (China) of breathing out try
Test control group 3 and Kang Ying is good for baby wipes (China) test control group 4；Group 5~group 15 respectively embodiment of the present invention 1~11 carry
The hip pad wet tissue test group of confession, that is, organize the 5 hip pad wet tissue test groups provided for the embodiment of the present invention 1, group 6 is the embodiment of the present invention
2 hip pad wet tissue test groups provided, group 7 is hip pad wet tissue test group ... provided in an embodiment of the present invention, group 15
The hip pad wet tissue test group provided for the embodiment of the present invention 11.
During experiment, the arm of subject is fixed, and the initial parameter index (water of fixing arm is measured with skinanalysis apparatus
Point) initial value and record；Each test specimen of equivalent is taken on the arm of each group subject, and smears uniform, and is existed respectively
5min, 15min, 30min, 60min test the moisture value and record of the recipient site of each subject.
3rd, result of the test refers to table 6 below, wherein, moistening effect is generally using two fingers of moisture content of skin and moisture content windage
Mark to characterize.Skin moisture content can embody the saturation state of skin, indicate the instant moisture-keeping efficacy of skin.Its value is got over
Greatly, illustrate that moisture content of skin is bigger, instant moistening effect is better.
Table 6
As can be seen from Table 6, in tested period, after subject's smearing uses contrast product, the change of moisture content of skin
Less, and as gradually reducing occur in the increase of tested time, the moisture content of skin of recipient site；And use this hair smearing
After the hip pad wet tissue product that bright embodiment provides, the water content of skin is than initial increase by 15% or so, moreover, with the tested time
Increase, the moisture content of skin of recipient site can substantially remain in 50% or so, it can be seen that, shield provided in an embodiment of the present invention
The moistening effect of stern wet tissue is substantially better than contrast product, and is more advantageous to pinning the water content of skin, reduces moisture of skin
Scatter and disappear.
(2) using skin sensing examination
1st, test specimen：Hip pad wet tissue and contrast product provided in an embodiment of the present invention are wonderful to think happy pleasant baby wipes
(France), shellfish parent baby wipes (Japan), warm breathe out that baby cleans wet paper handkerchief (China), Kang Ying is good for baby wipes (China).
2nd, test method：Select 30 healths at random from a certain area, in the recent period non-drug administration, nonbreast-fed women or
Gravid woman, the volunteer of non-constitution sensitivity.The hip pad wet tissue that contrast product and 1-11 of the embodiment of the present invention provide is divided
Group, numbering 1-15, group 1 are shellfish parent baby wipes (Japan) experiment for happy pleasant baby wipes (France) test group of wonderful think of, group 2
Group, group 3 breathe out baby to clean wet paper handkerchief (China) test group, organize 4 to be that Kang Ying is good for baby wipes (China) test group to be warm；Group 5~
Group 15 is respectively the hip pad wet tissue test group that the embodiment of the present invention 1~11 provides, that is, organizes 5 shields provided for the embodiment of the present invention 1
Stern wet tissue test group, group 6 are that hip pad wet tissue test group, the group 7 that the embodiment of the present invention 2 provides are what the embodiment of the present invention 3 provided
Hip pad wet tissue test group ... and so on, the hip pad wet tissue test group that group 15 provides for the embodiment of the present invention 11.Volunteer point
Shi Yong group 1~groups 15 wet tissue, and evaluated respectively from smooth feeling, glutinous soapy feeling, salubrious sense and four indexs of moist feeling.
3rd, result of the test：Wet tissue index performance is evaluated using hundred-mark system：Wherein smooth sense, salubrious sense, moist feeling three
Index percent value is bigger, illustrates that the smooth sense of the wet tissue product, salubrious sense, moist feeling are better；Glutinous soapy feeling percent value is smaller, says
It is smaller that the bright wet tissue product sticks soapy feeling.Concrete outcome refers to table 7 below.
Table 7
It can be seen that from the test result of upper table 7 compared to contrast product, hip pad wet tissue provided in an embodiment of the present invention
Smooth feeling, salubrious sense and moist feeling are above contrast product, and glutinous soapy feeling is less than contrast product, and therefore, the embodiment of the present invention provides
Hip pad wet tissue using skin sense more preferably.
Hip pad wet tissue provided in an embodiment of the present invention, which does not contain alcohol etc., easily makes skin become dry, coarse, lose bullet
Property, or even cause the component of the skin diseases such as skin allergy, but use it is pure natural, there is anti-inflammatory, is antibacterial, antiviral molten
Bacterium enzyme builds natural antisepsis and sterilization system, is not only able to effectively anti-corrosion, and gently non-stimulated to skin, safe and non-toxic.
Moreover, hip pad wet tissue provided in an embodiment of the present invention is good using skin sense and moistening effect is good, the moisture of skin can be effectively pinned.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
All any modification, equivalent and improvement made within refreshing and principle etc., should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of hip pad wet tissue, it is characterised in that including wet tissue liquid and wet tissue carrier；
The wet tissue liquid includes following component and the part by weight of each component is as follows：
Emollient：0.2%~0.5%；
Lysozyme：0.1%~0.5%；
PH adjusting agent：0.3%~0.6%；
Surplus is deionized water.
2. hip pad wet tissue as claimed in claim 1, it is characterised in that the wet tissue liquid includes the weight of following component and each component
Amount ratio is：
Emollient：0.2%；
Lysozyme：0.2%；
PH adjusting agent：0.6%；
Surplus is deionized water.
3. hip pad wet tissue as claimed in claim 1, it is characterised in that the wet tissue liquid includes the weight of following component and each component
Amount ratio is：
Emollient：0.2%~0.5%；
Lysozyme：0.1%~0.5%；
PH adjusting agent：0.3%~0.6%；
Skin conditioning agent：6%~10%；
Solubilizer：2%~5%；
Fungicide：3.2%~7.1%；
Surplus is deionized water.
4. hip pad wet tissue as claimed in claim 3, it is characterised in that the wet tissue liquid includes the weight of following component and each component
Amount ratio is：
Emollient：0.2%；
Lysozyme：0.5%；
PH adjusting agent：0.6%；
Skin conditioning agent：10%；
Solubilizer：2%；
Fungicide：3.2%；
Surplus is deionized water.
5. hip pad wet tissue as claimed in claim 1, it is characterised in that the wet tissue carrier is spunlace non-woven cloth, wet method nonwoven
Cloth, the one of which of needle punched non-woven fabrics or at least two composition.
6. impregnated wipe as claimed in claim 5, it is characterised in that the wet tissue carrier is spunlace non-woven cloth.
7. hip pad wet tissue as claimed in claim 1, it is characterised in that the emollient is caprylic/capric triglyceride, hydrogenation
Polyisobutene, neopentyl glycol dicaprylate/dicaprate, isononyl isononanoate, jojoba seed oil, Butyrospermum parkii fruit fat, deep-sea
Two section mustard oil, thorn A Gan trees the benevolence oily either one of which of camellia seed oil or at least two mixture；
The pH adjusting agent is at least two mixture in citric acid, sodium citrate, boric acid, malic acid or sorbic acid.
8. hip pad wet tissue as claimed in claim 3, it is characterised in that the skin conditioning agent is phytosterols oletate, red
At least two in bisabol, isohexadecane, glycerine, beta glucan, dipotassium glycyrrhizinate, decoyl hydroximic acid or glycerol caprylate
Mixture；
The solubilizer is rilanit special CO-40, maleic acid modified castor oil, castor-oil plant (RICINUSCOMMUNIS) seed are oily, different
The one of which or at least two mixture of propyl alcohol either three isostearate of PEG-160 anhydrous sorbitols；
The fungicide is poly hexamethylene biguanide, tasteless L antiseptics, triclosan, tricyclazole or didecyl Dimethy chlorine
Change at least three kinds of mixture in ammonium.
9. hip pad wet tissue as claimed in claim 4, it is characterised in that the emollient includes the weight of following component and each component
Amount ratio is：Water-soluble jojoba seed oil 0.2%；
The pH adjusting agent includes following component and the part by weight of each component is：Citric acid 0.1% and sodium citrate 0.5%；
The skin conditioning agent includes following component and the part by weight of each component is：Glycerine 8% and bisabolol 2%；
The solubilizer includes following component and the part by weight of each component is：Rilanit special CO-40 2%；
The fungicide includes following component and the part by weight of each component is：Tasteless L antiseptics 2%, poly hexamethylene biguanide
1% and didecyl Dimethy ammonium chloride 0.2%.
10. the preparation method of impregnated wipe as described in any one of claim 1~9, it is characterised in that include the following steps：
Formula according to the wet tissue liquid as described in any one of claim 1~9 weighs each component, spare；
The part deionized water is added into ingredients pot；
The emollient is added in the ingredients pot, is heated to 50 DEG C~60 DEG C, and is stirred to being completely dissolved；
It is to be cooled to be cooled to 20 DEG C~40 DEG C, the lysozyme is added, and stir evenly；
The pH adjusting agent is added, pH value is adjusted to 5~6, adds the remaining deionized water, obtain the wet tissue liquid；
By the wet tissue liquid with sterilizing after the wet tissue carrier according to part by weight be 3.3:1 is packaged.
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| CN110638359A (en) * | 2019-11-11 | 2020-01-03 | 苏州宝丽洁日化有限公司 | Preparation method of wet tissue without antibacterial agent residue on skin after use |
| CN111632014A (en) * | 2020-06-18 | 2020-09-08 | 广东景兴健康护理实业股份有限公司 | Preparation method and application of silk fibroin skin-beautifying sanitary wet tissue additive solution |
| WO2022139739A3 (en) * | 2020-12-21 | 2022-08-11 | Eczacibasi Tuketim Urunleri Sanayi Ve Ticaret Anonim Sirketi | Composition having a ph value compatible with ideal ph value of skin and skin product in which said composition is applied |
| CN116747340A (en) * | 2023-08-21 | 2023-09-15 | 露乐健康科技股份有限公司 | Bionic fetal fat composition, paper diaper, preparation method and application of paper diaper |
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Application publication date: 20180511 |