CN106691956A - Anti-inflammatory and bacteriostatic mouthwash - Google Patents
Anti-inflammatory and bacteriostatic mouthwash Download PDFInfo
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- CN106691956A CN106691956A CN201611087394.4A CN201611087394A CN106691956A CN 106691956 A CN106691956 A CN 106691956A CN 201611087394 A CN201611087394 A CN 201611087394A CN 106691956 A CN106691956 A CN 106691956A
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- mouthwash
- inflammatory
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- leek
- cymbopogon distans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/463—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- Life Sciences & Earth Sciences (AREA)
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- Engineering & Computer Science (AREA)
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- Oral & Maxillofacial Surgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
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Abstract
The invention discloses anti-inflammatory and bacteriostatic mouthwash. The anti-inflammatory and bacteriostatic mouthwash is prepared from the following components: a agrimonia pilosa and plantain herb mixed extract, humulus scandens merr and remote lemongrass herb mixed fermentation broth, a water hyacinth and leek flower mixed decoction solution, herba menthae essential oil, vitamin B12, sodium lauryl sulfate, sorbitol, monopotassium phosphate and purified water. Compared with conventional mouthwash, the mouthwash disclosed by the invention has the advantages that by synergism of all the components, the efficacy of quickly diminishing inflammation, preventing gingival bleeding and effectively inhibiting oral bacteria; meanwhile, food residues and soft scales left at diastema, gingival, buccal labial sulcus and other parts can be removed.
Description
Technical field
The present invention relates to mouthwash field, more particularly to a kind of antibacterial mouthwash of anti-inflammatory.
Background technology
Mouthwash, is also called oral washing liquid, is dental health product, with killing except the function of microorganism tartar, and prevents
Effect of the carious tooth, gingivitis and the halitosis that are only induced by it.The mucus that mouthwash also contributes to remove throat part is residual with food
Slag, can clean oral cavity, and pre- anti-caries and periodontitis etc. have cool mouthfeel.
When with periodontosis, its many bacterium for producing can be entered into the middle of blood, then by systemic circulation, is penetrated into
Other each positions of human body, so that immune cell activated, promotes to produce cell factor.Cell factor has destructiveness, is unfavorable for
Health.According to investigations, China 74% population it is different degrees of with mouth disease, reach World Health Organization's formulation
The people of oral health standard only has 0.22%, wherein in the middle of every 10 old men, it is full mouth anodontia just to have one.China is most common
Mouth disease includes：Canker sore, periodontosis, carious tooth, wherein periodontosis refer mainly to periodontitis and gingivitis, are common infection
Property mouth disease.The people for having 15% in developed country suffers from periodontosis, and suffers from periodontosis in the people that China has 2/3 unexpectedly, wherein
Human adult periodontal patient accounts for 97%, the exactly such periodontosis of main cause that more than 35 years old crowd loses tooth.Additionally, carious tooth
The incidence of disease be 45%, as the second largest mouth disease for being only second to periodontosis.With all kinds of mouth disease incidences of disease increase and
The augmentation of scope of falling ill, increasing people appreciates the harmfulness of mouth disease.Mouth disease brings patient not only
It is that absence of tooth or initiation halitosis are so simple, severe patient even can cause carcinoma of mouth, cerebral infarction, brain abscess, rheumatism or class wind
The diseases such as wet arthritis, skin disease, ephritis.
The content of the invention
Therefore, the purpose of the present invention is a kind of antibacterial mouthwash of anti-inflammatory.
The present invention is achieved through the following technical solutions：
A kind of antibacterial mouthwash of anti-inflammatory, is made up of following component by weight：Hairyvein agrimony and Asiatic plantain mixed extract 0.1-
0.3rd, strangle careless mix decoction liquor 3-5, Peppermint essential oil 0.4-0.6, dimension with leek with cymbopogon distans mixed fermentation liquid 2-4, water hyacinth
Raw element B12 0.2-0.5, sodium lauryl sulfate 0.6-0.8, sorbierite 0.8-1, potassium dihydrogen phosphate 0.4-0.6, pure water 100-
105。
Further：Described hairyvein agrimony is with Asiatic plantain mixed extract preparation method：Hairyvein agrimony is pressed with Asiatic plantain
3:1 mass ratio mixes, and then uses mass concentration to soak 2 hours at 40 DEG C for 2.35% sodium chloride solution, then mistake
Filter, pulverizes, using 80% concentration of volume percent alcohol solvent, by solid-liquid ratio 1:20, refluxing extraction 2h, is centrifuged at 50 DEG C
Supernatant, then concentrated by rotary evaporation, hairyvein agrimony and Asiatic plantain mixed extract needed for then freeze-drying is obtained.
Further：The strangle careless are with cymbopogon distans mixed fermentation liquid and preparation method thereof：Strangle careless and cymbopogon distans are pressed 1:3 mass
After ratio uniform mixing, the pure water of 5 times of addition cymbopogon distans quality is beaten 20min, mixed serum is obtained, in mixed serum
The brewer yeast of addition cymbopogon distans quality 5%, at 35 DEG C, ferments 5 hours, and 15min then is centrifuged with 2000r/min rotating speeds, then quiet
Put 4 hours, take its supernatant liquor, be concentrated into 1/5th of original volume, as required strangle careless and cymbopogon distans mixed fermentation liquid.
Further：Described water hyacinth mixes decoction liquid and preparation method thereof with leek：Water hyacinth is pressed with leek
10:After the mixing of 1 mass ratio, relative air humidity is placed on for 75%, temperature is 45 DEG C of environment lower 3 hours, and water is then added again
The pure water that 5 times of cucurbit quality, after big fire is boiled, truce 30min, then big fire is boiled, and small fire decocts 30min, and cooling is filtered,
Filtrate is obtained, to 1/3rd of original volume, depigmentaton obtains final product required water hyacinth and mixes decoction liquor with leek concentration filtrate.
Further：Mouthwash is swayed under 6-8 when using, is drunk in entrance and is spued containing 1-2min；Use 1-2 daily
It is secondary.
Using mouthwash of the invention, once a day, can cure within canker sore 1-2 days.
The beneficial effects of the invention are as follows：Compared with existing mouthwash, mouthwash of the present invention is by the collaboration between each composition
Mating reaction, can play quick anti-inflammatory, prevent bleeding gums, effectively suppress effect of oral bacteria, while can dispose depositing
The swill and soft dirt of diastema, gum, lip buccal groove etc. are stayed in, so as to reach cleaning oral cavity and suppress the mesh of bleeding gums
, it is capable of the phenomenon of rapid recovery bleeding gums；And mixed by hairyvein agrimony and Asiatic plantain mixed extract, strangle careless and cymbopogon distans
Close the synergy that zymotic fluid, water hyacinth mixs decoction liquor with leek, can so that mouthwash of the present invention have good anti-inflammatory,
Analgesic activity, can be used to preventing or treating canker sore, carious tooth and halitosis, and the auxiliary that can be used not only for oral cavity class inflammation is controlled
Treat, it is also possible to for regular oral health routine.
Specific embodiment
Embodiment 1
A kind of antibacterial mouthwash of anti-inflammatory, is made up of following component by weight：Hairyvein agrimony and Asiatic plantain mixed extract 0.1,
Strangle careless and cymbopogon distans mixed fermentation liquid 2, water hyacinth mix with leek decoction liquor 3, Peppermint essential oil 0.4, vitamin B12 0.2,
Sodium lauryl sulfate 0.6, sorbierite 0.8, potassium dihydrogen phosphate 0.4, pure water 100.
Embodiment 2
A kind of antibacterial mouthwash of anti-inflammatory, is made up of following component by weight：Hairyvein agrimony and Asiatic plantain mixed extract 0.3,
Strangle careless and cymbopogon distans mixed fermentation liquid 4, water hyacinth mix with leek decoction liquor 5, Peppermint essential oil 0.6, vitamin B12 0.5,
Sodium lauryl sulfate 0.8, sorbierite 1, potassium dihydrogen phosphate 0.6, pure water 105.
Embodiment 3
A kind of antibacterial mouthwash of anti-inflammatory, is made up of following component by weight：Hairyvein agrimony and Asiatic plantain mixed extract 0.2,
Strangle careless and cymbopogon distans mixed fermentation liquid 3, water hyacinth mix with leek decoction liquor 4, Peppermint essential oil 0.5, vitamin B12 0.3,
Sodium lauryl sulfate 0.7, sorbierite 0.9, potassium dihydrogen phosphate 0.5, pure water 102.
In above-described embodiment：
Described hairyvein agrimony is with Asiatic plantain mixed extract preparation method：Hairyvein agrimony and Asiatic plantain are pressed 3:1 mass ratio is mixed
Close, then use mass concentration to be soaked 2 hours at 40 DEG C for 2.35% sodium chloride solution, then filter, pulverize, using 80%
Concentration of volume percent alcohol solvent, by solid-liquid ratio 1:20, the refluxing extraction 2h at 50 DEG C, are centrifuged to obtain supernatant, then through overwinding
Turn to be concentrated by evaporation, hairyvein agrimony and Asiatic plantain mixed extract needed for then freeze-drying is obtained.
The strangle careless are with cymbopogon distans mixed fermentation liquid and preparation method thereof：Strangle careless and cymbopogon distans are pressed 1:3 mass ratios are uniform
After mixing, the pure water of 5 times of addition cymbopogon distans quality is beaten 20min, obtains mixed serum, to adding rue in mixed serum
The brewer yeast of herbaceous stem amount 5%, at 35 DEG C, ferments 5 hours, and 15min then is centrifuged with 2000r/min rotating speeds, then stands 4 hours,
Its supernatant liquor is taken, 1/5th of original volume are concentrated into, as required strangle careless and cymbopogon distans mixed fermentation liquid.
Described water hyacinth mixes decoction liquid and preparation method thereof with leek：Water hyacinth and leek are pressed 10:1 mass ratio
After example mixing, relative air humidity is placed on for 75%, temperature is 45 DEG C of environment lower 3 hours, and water hyacinth quality 5 is then added again
Pure water again, after big fire is boiled, truce 30min, then big fire is boiled, and small fire decocts 30min, and cooling, filtering obtains filtrate, dense
To 1/3rd of original volume, depigmentaton obtains final product required water hyacinth and mixes decoction liquor with leek contracting filtrate.
Mouthwash is swayed under 6-8 when using, is drunk in entrance and is spued containing 1-2min；It is daily to use 1-2 times.
Using mouthwash of the invention, once a day, canker sore can cure within 2-3 days.
Comparative example 1：It is only without hairyvein agrimony and Asiatic plantain mixed extract with the difference of embodiment 2.
Comparative example 2：It is only without strangle careless and cymbopogon distans mixed fermentation liquid with the difference of embodiment 2.
Comparative example 3：Mix decoction liquor with leek without water hyacinth with differing only in for embodiment 2.
Choose porphyromonas gingivalis, Escherichia coli, these three bacterium of staphylococcus aureus and refer to GB15979-2002
Appendix C 3 carries out antibacterial experiment（Process time is 3 minutes）：
Table 1
As can be seen from Table 1, the mouthwash fungistatic effect that prepared by the present invention is substantially, especially sterilized to staphylococcus aureus to imitate
Preferably, also, by test, mouthwash of the present invention is average more than 94% to the bacteriostasis rate of Prevotella, to viscosity for fruit
The bacteriostasis rate of actinomyces is average more than 97%.
Claims (5)
1. the antibacterial mouthwash of a kind of anti-inflammatory, it is characterised in that be made up of following component by weight：Hairyvein agrimony mixes with Asiatic plantain
Close extract 0.1-0.3, strangle careless and mix decoction liquor 3-5, peppermint essence with leek with cymbopogon distans mixed fermentation liquid 2-4, water hyacinth
Oily 0.4-0.6, vitamin B12 0.2-0.5, sodium lauryl sulfate 0.6-0.8, sorbierite 0.8-1, potassium dihydrogen phosphate 0.4-
0.6th, pure water 100-105.
2. the antibacterial mouthwash of a kind of anti-inflammatory according to claim 1, it is characterised in that：Described hairyvein agrimony mixes with Asiatic plantain
Closing method for preparing extractive is：Hairyvein agrimony and Asiatic plantain are pressed 3:1 mass ratio mixes, and it is 2.35% then to use mass concentration
Sodium chloride solution soaked 2 hours at 40 DEG C, then filter, pulverize, using 80% concentration of volume percent alcohol solvent, press
Solid-liquid ratio 1:20, the refluxing extraction 2h at 50 DEG C, are centrifuged to obtain supernatant, then are concentrated by rotary evaporation, then freeze-drying system
Hairyvein agrimony needed for obtaining and Asiatic plantain mixed extract.
3. the antibacterial mouthwash of a kind of anti-inflammatory according to claim 1, it is characterised in that：The strangle careless mix hair with cymbopogon distans
Zymotic fluid preparation method is：Strangle careless and cymbopogon distans are pressed 1:3 mass ratios uniformly after mixing, add the pure of 5 times of cymbopogon distans quality
Water, is beaten 20min, obtains mixed serum, to the brewer yeast that cymbopogon distans quality 5% is added in mixed serum, at 35 DEG C, fermentation 5
Hour, 15min is then centrifuged with 2000r/min rotating speeds, then 4 hours are stood, its supernatant liquor is taken, it is concentrated into five points of original volume
One of, as required strangle careless and cymbopogon distans mixed fermentation liquid.
4. the antibacterial mouthwash of a kind of anti-inflammatory according to claim 1, it is characterised in that：Described water hyacinth is mixed with leek
Closing decoction liquid and preparation method thereof is：Water hyacinth and leek are pressed 10:After the mixing of 1 mass ratio, being placed on relative air humidity is
75%, temperature is 45 DEG C of environment lower 3 hours, and the pure water of 5 times of water hyacinth quality is then added again, after big fire is boiled, ceases fire
30min, then big fire is boiled, and small fire decocts 30min, and cooling, filtering obtains filtrate, and concentration filtrate is gone to 1/3rd of original volume
Pigment, obtains final product required water hyacinth and mixes decoction liquor with leek.
5. the application method of the antibacterial mouthwash of a kind of anti-inflammatory according to claim 1, it is characterised in that：To be gargled when using
Water is swayed under 6-8, is drunk in entrance and is spued containing 1-2min；It is daily to use 1-2 times.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611087394.4A CN106691956A (en) | 2016-12-01 | 2016-12-01 | Anti-inflammatory and bacteriostatic mouthwash |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611087394.4A CN106691956A (en) | 2016-12-01 | 2016-12-01 | Anti-inflammatory and bacteriostatic mouthwash |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106691956A true CN106691956A (en) | 2017-05-24 |
Family
ID=58935402
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611087394.4A Withdrawn CN106691956A (en) | 2016-12-01 | 2016-12-01 | Anti-inflammatory and bacteriostatic mouthwash |
Country Status (1)
| Country | Link |
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| CN (1) | CN106691956A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108392460A (en) * | 2018-05-23 | 2018-08-14 | 安徽广生堂生物科技有限公司 | A kind of Chinese prescription extraction mouth cleaning solution and its manufacturing method |
| CN108835136A (en) * | 2018-05-30 | 2018-11-20 | 金寨毛竹湾农业科技有限公司 | A kind of piglet hog house disinfection liquid and preparation method thereof |
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| CN105770679A (en) * | 2016-05-03 | 2016-07-20 | 张绪伟 | Chinese herbal mouthwash for treating fungal infection of oral cavity |
| CN105997659A (en) * | 2016-06-21 | 2016-10-12 | 江苏奇力康皮肤药业有限公司 | Anti-inflammation and anti-bacterium mouth wash |
-
2016
- 2016-12-01 CN CN201611087394.4A patent/CN106691956A/en not_active Withdrawn
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| CN102784082A (en) * | 2012-08-02 | 2012-11-21 | 陈斌 | Antiallergic tooth-protection toothpaste |
| CN103767925A (en) * | 2012-10-23 | 2014-05-07 | 路明 | Plantain herb teeth-protecting toothpaste |
| CN104840388A (en) * | 2015-04-29 | 2015-08-19 | 广州立白企业集团有限公司 | Application of plant extracts to oral care products |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108392460A (en) * | 2018-05-23 | 2018-08-14 | 安徽广生堂生物科技有限公司 | A kind of Chinese prescription extraction mouth cleaning solution and its manufacturing method |
| CN108835136A (en) * | 2018-05-30 | 2018-11-20 | 金寨毛竹湾农业科技有限公司 | A kind of piglet hog house disinfection liquid and preparation method thereof |
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Application publication date: 20170524 |