CN106689198A - Compound hydrogen peroxide disinfectant as well as preparation method and application thereof<0} - Google Patents
Compound hydrogen peroxide disinfectant as well as preparation method and application thereof<0} Download PDFInfo
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- CN106689198A CN106689198A CN201710001147.6A CN201710001147A CN106689198A CN 106689198 A CN106689198 A CN 106689198A CN 201710001147 A CN201710001147 A CN 201710001147A CN 106689198 A CN106689198 A CN 106689198A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/22—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing ingredients stabilising the active ingredients
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/14—Disinfection, sterilisation or deodorisation of air using sprayed or atomised substances including air-liquid contact processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2209/00—Aspects relating to disinfection, sterilisation or deodorisation of air
- A61L2209/20—Method-related aspects
- A61L2209/21—Use of chemical compounds for treating air or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2209/00—Aspects relating to disinfection, sterilisation or deodorisation of air
- A61L2209/20—Method-related aspects
- A61L2209/21—Use of chemical compounds for treating air or the like
- A61L2209/211—Use of hydrogen peroxide, liquid and vaporous
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- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
The invention provides a compound hydrogen peroxide disinfectant which is prepared from the following ingredients by percentage composition: hydrogen peroxide with the volume concentration of 5.0-7.0%, disodium edta with the mass concentration of0.05-0.02%, citric acid with the mass concentration of 0.05-0.15%, lactic acid with the mass concentration of 0.05-0.15% and the balance of water replenished until the total percentage is 100%. <0}Sterilization-enhancing agents, namely the citric acid and the lactic acid are added into a hydrogen peroxide solution, meanwhile the disodium edta is added as a complex stabilizer, and the citric acid is also a complex stabilizer, so that long-term stability of the hydrogen peroxide disinfectant is kept, and the quality guarantee period is one year. <0}The compound hydrogen peroxide disinfectant is low in effective use concentration, relatively low in residual toxicity and free from dilution, and is convenient to apply since a stock solution can be directly used for disinfection.
Description
Technical field
The invention belongs to disinfection sanitizer field, and in particular to a kind of compound disinfectant and its preparation method and application.
Background technology
Disinfectant, is colourless liquid, there is intense irritation smell.For killing pathogenic microorganism on communication media, make it
Innoxious requirement is reached, pathogenic microorganism is eliminated outside human body, cut off the route of transmission of infectious disease, reach control infectious disease
Purpose.Various countries focus on to find environmental sound and act on quick disinfectant in recent years, wherein with hydrogen peroxide and titanium dioxide
Chlorine body sterilization more attracts attention, and the sterilization of ozone also has wide use value.The species of disinfectant has a lot, conventional kind
Class is including potassium permanganate, formaldehyde, glutaraldehyde, oxirane, Peracetic acid, hydrogen peroxide, chlorine dioxide etc..
Hydrogen peroxide is that one kind uses disinfectant earlier.The disinfectant because of non-residual toxicity, bactericidal action by force and again
It is recognized.At present, European and American countries have been widely used in sterilization field.Hydrogen peroxide is a kind of bactericidal agent, can kill bag
Bacterial propagule, brood cell, fungi and virus are included in interior various microorganisms.The major antibacterial effect of hydrogen peroxide is by its decomposition
The various chemical groups for producing afterwards, such as active oxygen and its derivative ,-OH etc., have killing action to microorganism.They not only may be used
To destroy the permeability barrier of microorganism, and protein, enzyme, amino acid and the nucleic acid of microorganism can be destroyed, cause its dead.
Used as bactericidal agent, hydrogen peroxide generally uses concentration requirement 10%~25%, acts on 60 minutes；As disappearing
Poison, typically with 3%~6% concentration, act on 10 minutes.It is unstable at low concentrations yet with hydrogen peroxide, easily decompose, point
Hydrogen peroxide after solution can not reach the purpose of sterilization, therefore, the concentration of commercially available hydrogen peroxide is generally 28%-30%, therefore
Using preceding, hydrogen peroxide needs dilution operation, and this not only makes hydrogen peroxide using being restricted, and can also influence the sterilization of hydrogen peroxide
Effect.
At present, Patent publication No CN 102084869 discloses a kind of compound Hydrogen Peroxide Disinfectant, and specific utilization double eight/
Ten alkyl dimethyl ammonium chlorides have very strong affinity to thalline, promote thalline to be disintegrated dead；Glutaric acid has association with hydrogen peroxide
Same-action, can produce the chain reaction of free radical, make it have stronger sterilizing ability；Phytic acid and AEO point
Hydroxyl in son increased the stability of hydrogen peroxide.But the compound Hydrogen Peroxide Disinfectant is not improved hydrogen peroxide
Disinfecting power, and production cost is high.
The content of the invention
In view of this, it is an object of the invention to provide a kind of bactericidal action that can be improved, and its stability is not influenceed
Chemical cooperated Compound Hydrogen Peroxide Disinfectant.
In order to realize foregoing invention purpose, the present invention provides following technical scheme：
The invention provides a kind of Compound Hydrogen Peroxide Disinfectant, including hydrogen peroxide, disodium ethylene diamine tetraacetate, citron
Acid, lactic acid and water；Including following percentage composition component：5.0%~7.0% hydrogen peroxide, mass concentration 0.005%~
0.02% disodium ethylene diamine tetraacetate, the citric acid of mass concentration 0.05%~0.15%, mass concentration 0.05%~
0.15% lactic acid, 100% is supplemented to water.
Preferably, the hydrogen peroxide of volumetric concentration 5.5%~6.5%, the ethylenediamine of mass concentration 0.008%~0.015%
Tetraacethyl disodium, the citric acid of mass concentration 0.07%~0.15%, the lactic acid of mass concentration 0.07%~0.15%, is mended with water
It is charged to 100%.
Preferably, including following percentage composition component：The hydrogen peroxide of volumetric concentration 6.0%, mass concentration 0.01%
The citric acid of disodium ethylene diamine tetraacetate, mass concentration 0.1%, the lactic acid of mass concentration 0.1%, 100% is supplemented to water.
Preferably, the volumetric concentration of the hydrogenperoxide steam generator is 28~30%.
Preferably, purity >=99.7% of the disodium ethylene diamine tetraacetate.
Preferably, purity >=99.7% of the citric acid.
Preferably, purity >=99.7% of the lactic acid.
Preferably, the water is distilled water, distilled water, deionized water, reverse osmosis water or ultra-pure water.
The invention provides a kind of preparation method of Compound Hydrogen Peroxide Disinfectant, by hydrogen peroxide, ethylenediamine tetra-acetic acid
The mixing of disodium, citric acid, lactic acid and water, obtains Compound Hydrogen Peroxide Disinfectant.
The invention provides application of the Compound Hydrogen Peroxide Disinfectant in sterilization；The sterilization includes that environment disappears
Poison, air sterillization, sterilization of instruments and food sterilization.
The invention provides a kind of Compound Hydrogen Peroxide Disinfectant, including hydrogen peroxide, disodium ethylene diamine tetraacetate, citron
Acid, lactic acid and water.While the present invention doses sterilized medicine synergist citric acid and lactic acid in hydrogenperoxide steam generator, ethylenediamine is added
Tetraacethyl disodium as complex compound stabilizer, meanwhile, citric acid is also complex compound stabilizer, by building sour environment, and not
The stability of influence hydrogen peroxide reaches the purpose of Synergistic sterilizing, and the shelf-life is 1 year.The compound hydrogen peroxide that the present invention is provided disappears
The effective concentration of toxic agent is relatively low, and residual toxicity is relatively low, it is not necessary to dilute, and is directly used as sterilization using stoste, using convenient.
Meanwhile, the disinfectant that the present invention is provided has the advantages that toxic and side effect is smaller and wide spectrum kills microorganism, can be fast
Speed kills bacterial propagule.By dosing complex compound stabilizer and synergist, concentration is both ensure that, cost is reduced again,
And convenient use.Therefore there is wide market in hospital disinfection, health and epidemic prevention sterilization and home-use sterilization.The present invention is provided
Disinfectant usage for immersion and smear, directly use stoste to surface disinfection；Aerosol spray can also be carried out to disappear
Malicious room air and body surface.Can be used for the Antiepidemic sterilizing of common acute respiratory tract infection encephalapthy agent, it can also be used to tuberculosis
The sterilization of mycobacteria and other common bacteria pathogens.
Specific embodiment
The invention provides a kind of Compound Hydrogen Peroxide Disinfectant, including hydrogen peroxide, disodium ethylene diamine tetraacetate, citron
Acid, lactic acid and water.
The Compound Hydrogen Peroxide Disinfectant that the present invention is provided includes hydrogen peroxide.Based on percentage composition, the hydrogen peroxide
Volumetric concentration be 5.0%~7.0%, preferably 5.5%~6.5%, more preferably 6.0%.The source of the hydrogen peroxide
It is the hydrogenperoxide steam generator that commercially available volumetric concentration is 28%~30%.
The Compound Hydrogen Peroxide Disinfectant that the present invention is provided includes disodium ethylene diamine tetraacetate.The ethylenediamine tetra-acetic acid two
Mass concentration of the sodium in disinfectant is 0.005%~0.02%, preferably 0.008%~0.015%, more preferably
0.01%.In the present invention, the disodium ethylene diamine tetraacetate purity preferably >=99.7%, more preferably >=99.8%.
The Compound Hydrogen Peroxide Disinfectant that the present invention is provided includes citric acid.Quality of the citric acid in disinfectant is dense
It is 0.05%~0.2% to spend, preferably 0.07%~0.15%, more preferably 0.1%.The purity of the citric acid >=
99.7%.
The Compound Hydrogen Peroxide Disinfectant that the present invention is provided includes lactic acid.Mass concentration of the lactic acid in disinfectant be
0.05%~0.2%, preferably 0.07%~0.15%, more preferably 0.1%.Purity >=99.7% of the lactic acid, it is more excellent
Elect >=99.8% as.
The Compound Hydrogen Peroxide Disinfectant that the present invention is provided includes the water of surplus.The present invention is to the species of the water without spy
Different limitation, using disinfectant water well known to those skilled in the art.In the present invention, the water is preferably distillation
Water, distilled water, deionized water, reverse osmosis water or ultra-pure water.
Present invention also offers a kind of preparation method of Compound Hydrogen Peroxide Disinfectant, by hydrogen peroxide, ethylenediamine tetrem
The mixing of acid disodium, citric acid, lactic acid and water, obtains Compound Hydrogen Peroxide Disinfectant.
In the present invention, the method for the mixing is not particularly limited, using mixing side well-known to those skilled in the art
Method.In the present invention, the preferred stainless steel reaction container of container of the mixing.
In the present invention, the mixed liquor that will preferably be obtained after the mixing is stirred, and be sterilized agent.The speed of the stirring
Degree is not particularly limited, stirring scheme well-known to those skilled in the art.The time of the stirring is not particularly limited,
Untill component in solution dissolves.The purpose of the stirring makes disodium ethylene diamine tetraacetate, citric acid, lactic acid molten in the solution
Solution, while being well mixed each component, obtains Compound Hydrogen Peroxide Disinfectant.
In the present invention, Compound Hydrogen Peroxide Disinfectant is preferably dispensed into clean, sterilization and the plastic bottle of airing and seals up for safekeeping.
The invention provides application of the Compound Hydrogen Peroxide Disinfectant in sterilization；The sterilization includes that environment disappears
Poison, air sterillization, sterilization of instruments and food sterilization.
In the present invention, during the environment disinfected, the hydrogen peroxide volumetric concentration of the Compound Hydrogen Peroxide Disinfectant is preferred
It is 5.5%~7%, more preferably 6%.
In the present invention, during the air sterillization, the hydrogen peroxide volumetric concentration of the Compound Hydrogen Peroxide Disinfectant is preferred
It is 5.5%~7%, more preferably 6%.
During the food sterilization, the hydrogen peroxide volumetric concentration of the Compound Hydrogen Peroxide Disinfectant is preferably 5.0%~
6.0%, more preferably 5.5%.
During the sterilization of instruments, the hydrogen peroxide volumetric concentration of the Compound Hydrogen Peroxide Disinfectant is preferably 5.5%~
7%, more preferably 6%.
A kind of Compound Hydrogen Peroxide Disinfectant provided the present invention with reference to embodiment and its preparation method and application
It is described in detail, but they can not be interpreted as limiting the scope of the present invention.
Embodiment 1
Weigh that disodium ethylene diamine tetraacetate, citric acid and lactic acid are standby, by 30% hydrogenperoxide steam generator, ethylenediamine tetrem
Acid disodium, citric acid, lactic acid and water are mixed in stainless steel reaction container, stirring, are configured to the peroxidating of volumetric concentration 5.0%
Hydrogen, the disodium ethylene diamine tetraacetate of mass concentration 0.02%, the citric acid of mass concentration 0.05%, the breast of mass concentration 0.05%
Acid, 100% is supplemented to water, obtains 5.0% hydrogen peroxide compound disinfectant.
Embodiment 2
Weigh that disodium ethylene diamine tetraacetate, citric acid and lactic acid are standby, by 30% hydrogenperoxide steam generator, ethylenediamine tetrem
Acid disodium, citric acid, lactic acid and water are mixed in stainless steel reaction container, stirring, are configured to the peroxidating of volumetric concentration 7.0%
Hydrogen, the disodium ethylene diamine tetraacetate of mass concentration 0.005g/L, the citric acid of mass concentration 0.2%, the breast of mass concentration 0.2%
Acid, 100% is supplemented to water, obtains 7.0% hydrogen peroxide compound disinfectant.
Embodiment 3
Weigh that disodium ethylene diamine tetraacetate, citric acid and lactic acid are standby, by 30% hydrogenperoxide steam generator, ethylenediamine tetrem
Acid disodium, citric acid, lactic acid and water are mixed in stainless steel reaction container, stirring, are configured to the peroxidating of volumetric concentration 5.5%
Hydrogen, the disodium ethylene diamine tetraacetate of mass concentration 0.015%, the citric acid of mass concentration 0.07%, mass concentration 0.07%
Lactic acid, 100% is supplemented to water, obtains 5.5% hydrogen peroxide compound disinfectant.
Embodiment 4
Weigh that disodium ethylene diamine tetraacetate, citric acid and lactic acid are standby, by 30% hydrogenperoxide steam generator, ethylenediamine tetrem
Acid disodium, citric acid and water are mixed in stainless steel reaction container, stirring, are configured to the hydrogen peroxide of volumetric concentration 6.5%, matter
The disodium ethylene diamine tetraacetate of amount concentration 0.008%, the citric acid of mass concentration 0.15%, the lactic acid of mass concentration 0.15%,
100% is supplemented to water, 6.5% hydrogen peroxide compound disinfectant is obtained.
Embodiment 5
Weigh that disodium ethylene diamine tetraacetate, citric acid and lactic acid are standby, by 30% hydrogenperoxide steam generator, ethylenediamine tetrem
Acid disodium, citric acid and water are mixed in stainless steel reaction container, stirring, are configured to the hydrogen peroxide of volumetric concentration 6.0%, matter
The disodium ethylene diamine tetraacetate of concentration 0.01% is measured, the citric acid of mass concentration 0.1%, the lactic acid of mass concentration 0.1% uses water
100% is supplemented to, 6.0% hydrogen peroxide compound disinfectant is obtained.
Embodiment 6~10
Carry out killing gemma experiment by test strain of bacillus subtilis black variety gemma, microbiological contamination pieces of cloth are direct plungeed into and is contained
Taken out after certain hour is acted in 20ml disinfectant plates, under normal temperature, be put into the test tube equipped with 5ml nertralizers (in having passed through
With agent screening test, nertralizer is the normal saline solution containing 1% sodium thiosulfate), shake 100 times repeatedly, place half an hour
After carry out count plate, with 6%H2O2The killing rate of solution is tested as positive control, using distilled water as blank, with reality
The hydrogen peroxide compound disinfectant prepared in example 1~5 is applied as experimental group.
Killing rate (%)=(organize the average institute of bacterium piece after the average contained colony forming single-digit-sterilization of blank control group bacterium piece
Containing colony forming single-digit) the average contained colony forming single-digit of ÷ blank control group bacterium piece.Bactericidal data is shown in Table 1.
The killing rate that 16 kinds of thimerosal effect different times of table kill bacterial spore compares
As can be seen from Table 1, the hydrogen peroxide compound disinfectant that embodiment 1~5 is prepared becomes to hay bacillus black
Plant the killing rate and 6%H of gemma2O2Solution ratio, has a clear superiority, and 30min killing rates reach 90.36%~93.56%,
90min killing rates reach 99.98%~100%.From the point of view of the efficiency for killing gemma, the peroxidating that embodiment 1~5 is prepared
Hydrogen compound disinfectant has fireballing feature.
Embodiment 11
Weigh disodium ethylene diamine tetraacetate and hydrochloric acid is standby, by 30% hydrogenperoxide steam generator, disodium ethylene diamine tetraacetate,
Hydrochloric acid and water are mixed in stainless steel reaction container, stirring, are configured to the hydrogen peroxide of volumetric concentration 6.0%, mass concentration
0.01% disodium ethylene diamine tetraacetate, the hydrochloric acid of volumetric concentration 0.1%, 100% is supplemented to water, obtains 6.0% peroxide
Change hydrogen-hydrochloric acid compound disinfectant.
Embodiment 5 is prepared 6.0% hydrogen peroxide-citric acid-lactic acid compound disinfectant and 6.0% peroxidating
Hydrogen-hydrochloric acid compound disinfectant under room temperature condition while deposit 1 year.
After storage 6.0% hydrogen peroxide-citric acid-lactic acid compound disinfectant and 6.0% hydrogen peroxide-hydrochloric acid it is multiple
Square disinfectant carries out sterilizing experiment as disinfectant.Carry out killing gemma by test strain of bacillus subtilis black variety gemma
Experiment, microbiological contamination pieces of cloth are direct plungeed into the plate of disinfectant containing 20ml, are taken out after certain hour is acted under normal temperature, are put into and are equipped with
(by nertralizer screening test, nertralizer has been that the physiology salt containing 1% sodium thiosulfate is water-soluble in the test tube of 5ml nertralizers
Liquid), shake 100 times repeatedly, count plate is carried out after placing half an hour, with 6%H2O2The killing rate of solution is tried as positive control
Test, using distilled water as blank, with the hydrogen peroxide compound disinfectant and 6.0% peroxide that are prepared in embodiment 5
Change hydrogen-hydrochloric acid compound disinfectant as experimental group.
Killing rate is calculated according to the method for embodiment 6~10.Bactericidal data is shown in Table 2.
The killing rate that 22 kinds of thimerosal effect different times of table kill bacterial spore compares
As shown in Table 2, the hydrogen peroxide-citric acid-lactic acid compound disinfectant of the 6.0% of the preparation of embodiment 5 compares 6%H2O2-
The killing rate of hydrochloric acid solution has obvious advantage, illustrates prepared by the embodiment of the present application 5 6.0% hydrogen peroxide-citric acid-breast
Sour compound disinfectant less, illustrates that hydrogen peroxide-citric acid-lactic acid compound is killed by sterilizing efficiency change after long-term placement
Toxic agent compares 6%H2O2The good stability of-HCl solution, bactericidal action is strong, is adapted to long-term preservation and uses.Simultaneously also explanation citric acid and
Lactic acid is to the synergic remove of hydrogen peroxide not just simple H+Effect.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (10)
1. a kind of Compound Hydrogen Peroxide Disinfectant, including hydrogen peroxide, disodium ethylene diamine tetraacetate, citric acid, lactic acid and water；Bag
Include following percentage composition component：The hydrogen peroxide of volumetric concentration 5.0%~7.0%, the second of mass concentration 0.005%~0.02%
Edetate disodium, the citric acid of mass concentration 0.05%~0.15%, the lactic acid of mass concentration 0.05%~0.15% is used
Water is supplemented to 100%.
2. disinfectant according to claim 1, it is characterised in that including following percentage composition component：Volumetric concentration 5.5%
~6.5% hydrogen peroxide, the disodium ethylene diamine tetraacetate of mass concentration 0.008%~0.015%, mass concentration 0.07%~
0.12% citric acid, the lactic acid of mass concentration 0.07%~0.12%, 100% is supplemented to water.
3. disinfectant according to claim 1, it is characterised in that including following percentage composition component：Volumetric concentration 6.0%
Hydrogen peroxide, the disodium ethylene diamine tetraacetate of mass concentration 0.01%, the citric acid of mass concentration 0.1%, the breast of mass concentration 0.1%
Acid, 100% is supplemented to water.
4. the disinfectant according to Claims 1 to 4 any one, it is characterised in that the volume of the hydrogenperoxide steam generator
Concentration is 28%~30%.
5. the disinfectant according to Claims 1 to 4 any one, it is characterised in that the disodium ethylene diamine tetraacetate
Purity >=99.7%.
6. the disinfectant according to Claims 1 to 4 any one, it is characterised in that the purity of the citric acid >=
99.7%.
7. the disinfectant according to Claims 1 to 4 any one, it is characterised in that purity >=99.7% of the lactic acid.
8. the disinfectant according to Claims 1 to 4 any one, it is characterised in that the water is distilled water, distilled water,
Deionized water, reverse osmosis water or ultra-pure water.
9. the preparation method of the disinfectant described in claim 1~8 any one, it is characterised in that by hydrogen peroxide, ethylenediamine
The mixing of tetraacethyl disodium, citric acid, lactic acid and water, obtains Compound Hydrogen Peroxide Disinfectant.
10. prepared by the method described in the Compound Hydrogen Peroxide Disinfectant or claim 9 described in claim 1~8 any one
Application of the Compound Hydrogen Peroxide Disinfectant in sterilization；
The sterilization includes environment disinfected, air sterillization, sterilization of instruments and food sterilization.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109418264A (en) * | 2017-09-04 | 2019-03-05 | 上海利康消毒高科技有限公司 | Unitary peroxyacetic acid disinfectant and preparation method thereof |
| CN115487340A (en) * | 2022-10-31 | 2022-12-20 | 振德医疗用品股份有限公司 | Bacterial cellulose dressing loaded with active oxygen and preparation method thereof |
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| CN102802677A (en) * | 2009-06-29 | 2012-11-28 | 美你康株式会社 | System for sterilizing contact lens |
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| CN115487340B (en) * | 2022-10-31 | 2023-11-17 | 振德医疗用品股份有限公司 | Bacterial cellulose dressing loaded with active oxygen and preparation method thereof |
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