CN106668849A - Composition kit for preventing and curing peculiar smells of human bodies and using method thereof - Google Patents

Composition kit for preventing and curing peculiar smells of human bodies and using method thereof Download PDF

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Publication number
CN106668849A
CN106668849A CN201611264444.1A CN201611264444A CN106668849A CN 106668849 A CN106668849 A CN 106668849A CN 201611264444 A CN201611264444 A CN 201611264444A CN 106668849 A CN106668849 A CN 106668849A
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parts
agent
bed body
treatment
composition kit
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高敏
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City Of Jiangyin Miao Sen Tese Life Science Research Institute Co Ltd
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City Of Jiangyin Miao Sen Tese Life Science Research Institute Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4826Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00Anti-perspirants or body deodorants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21004Trypsin (3.4.21.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/88Two- or multipart kits

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Abstract

The invention belongs to the medical field, and specifically relates to a composition kit for preventing and curing peculiar smells of human bodies and a using method thereof. The composition kit comprises an agent A and an agent B, wherein the agent A comprises trypsin and NaHCO3; and the agent B comprises a mussel soft tissue extract, tea tree essential oil and lavender essential oil. The composition kit disclosed by the invention can be used for preventing and curing the peculiar smells of the human bodies, the infection of microorganisms is controlled, and an independent product having good curative effect and short treatment cycle and being free of toxic and side effects is provided for patients.

Description

A kind of composition kit and its application method for preventing and treating bed body smell
Technical field
The invention belongs to field of medicaments, more particularly to it is a kind of prevent and treatment bed body smell composition kit and its Application method.
Background technology
Bed body smell, refers to that a certain position of body produces different journeys due to the body of gland penetrating not reason such as smooth or bacterial action The peculiar smell of degree, with halitosis, underarm odor, foot odour as common.Halitosis refers to such as nose, nose from oral cavity or other cavitys full of air Sinus, pharynx, the foul smell for being given out.Underarm odor refers to that the sweat of secretion has special stink or sweat that stink is produced after decomposition.It is smelly Sweat disease is more common in the position where hidrosis, sweat are difficult evaporation and apocrine sweat gland, such as armpit, groin, foot, crissum, vulva, navel Nest and female breast lower section etc., it is most commonly seen with foot and bromhidrosis.Foot odour is, because arch of the foot sweat gland is more, easily to perspire, In sweat except moisture content, salt exceptionally, lactic acid and urea are also contained.Under the conditions of hidrosis, bacterium amount reproduction on pin is simultaneously decomposed Keratoprotein, along with the urea in sweat, lactic acid, can thus send a kind of stink.
In order to control these bed body smells, the method for using so far is all more passive, such as often brush teeth, have a bath or make It is deodorant with the spraying containing spices.Existing deodorant, its major function is to eliminate underarm odor, foot odour, halitosis etc., and commercially available prod is more It is antiperspirant, bactericide and stink masking agent.It is raw material to use compound mostly, there is different degrees of toxicity or skin irritatin Property.The treatment methods such as recent also useful laser surgery, such as remove the apocrine sweat gland for concentrating on armpit position, but surgery Financial cost needed for operation is larger, and postoperative social activities is restricted, also more long the time required to treatment, and cannot thorough root Control.
Mussel (Mytilusedulis Linnaeus) is a kind of sea mollusk, belongs to bivalve shellfish, is commonly called as " blue or green Mouthful " and " mussel ", each coastwise contries of throughout world.Mussel species are various, and only coastal area of china just has kind more than 30, and economic worth is higher Have kind more than 10, wherein Mytilus galloprovincialis, Perna viridis and Trachyostracous mussel is main breed variety.Enriched Mussel containing protein, fat, The nutrients such as carbohydrate, calcium, phosphorus, iron, riboflavin, niacin, and with medical value very high.
Trypsase (Trypsin, Parenzyme), EC 3.4.21.4 are the one kind extracted from the pancreas of ox, sheep, pig Serine protein hydrolase.After the precursor trypsinogen of pancreas manufacture is secreted into small intestine, erepsin activates it, as pancreas egg White enzyme.Trypsase is endopeptidase, the carboxyl that it can optionally in the lysine and arginine residues of hydrolyzed peptide chain. Trypsase not only plays digestive ferment, and can also limit decomposition chymotrypsinogen, procarboxypeptidase, phosphatide proenzyme etc. other The precursor of enzyme, plays activation.
Sodium acid carbonate (chemical formula:NaHCO3) be compound one kind, be referred to as sodium bicarbonate, sodium bicarbonate, heavy carbonic hydrogen Deng.White at normal temperatures powdered, slight bitter, taste is salty.As pharmaceuticals, controlling for hyperchlorhydria can be used for as plumper Treat.Can also be used for the food such as coffee and enamel.With monoclinic system crystal, carbon dioxide and water are produced after heating, become carbon Sour sodium anhydride.Industrially, generated with intermediate material when manufacturing sodium carbonate, can be used as the pharmaceuticals such as plumper or yeast powder or two Oxidation carbon generating agent etc. is used, and can play deodorant and except acid function.
The content of the invention
To solve the deficiencies such as prior art toxicity is big, side effect is big, cannot effect a radical cure, the present invention proposes a kind of prevention and treats The composition kit of bed body smell, can be used for preventing and treating bed body smell, microorganism infection be controlled, for patient provides treatment Imitate, treatment cycle is short, without the product for relying on, having no toxic side effect.
To achieve the above object, the present invention proposes a kind of composition kit for preventing and treating bed body smell, its feature It is that the composition kit of the prevention and treatment bed body smell includes A agent and B agent, wherein, based on composition total weight, The A agent includes:Trypsase 0.1-20 parts, NaHCO30.1-10 parts;The B agent includes mussel soft tissue extract 0.1- 15 parts, tea tree ethereal oil 0.1-5 parts, Lavender 0.1-5 parts.
The composition kit of one or more implementation methods of the invention, the prevention and treatment bed body smell is pressed Composition total weight meter, wherein, the A agent includes:Trypsase is such as 0.1 part, 0.2 part, 1 part, 1.5 parts, 2 parts, 2.5 Part, 3 parts, 3.5 parts, 4 parts, 4.5 parts, 5 parts, 5.5 parts, 6 parts, 6.5 parts, 7 parts, 7.5 parts, 8 parts, 8.5 parts, 9 parts, 9.5 parts, 10 Part, 10.5 parts, 11 parts, 11.5 parts, 12 parts, 12.5 parts, 13 parts, 13.5 parts, 14 parts, 14.5 parts, 15 parts, 15.5 parts, 16 parts, 16.5 parts, 17 parts, 17.5 parts, 18 parts, 18.5 parts, 19 parts, 19.5 parts, 20 parts etc., NaHCO3Such as 0.1 part, 0.2 part, 1 Part, 1.5 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts, 4.5 parts, 5 parts, 5.5 parts, 6 parts, 6.5 parts, 7 parts, 7.5 parts, 8 parts, 8.5 Part, 9 parts, 9.5 parts, 10 parts etc.;The B agent includes:Mussel soft tissue extract is such as 0.1 part, 1 part, 1.5 parts, 2 parts, 2.5 Part, 3 parts, 3.5 parts, 4 parts, 4.5 parts, 5 parts, 5.5 parts, 6 parts, 6.5 parts, 7 parts, 7.5 parts, 8 parts, 8.5 parts, 9 parts, 9.5 parts, 10 Part, 10.5 parts, 11 parts, 11.5 parts, 12 parts, 12.5 parts, 13 parts, 13.5 parts, 14 parts, 14.5 parts, 15 parts etc., tea tree ethereal oil is example Such as 0.1 part, 1 part, 1.5 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts, 4.5 parts, 5 parts, Lavender is such as 0.1 part, 1 Part, 1.5 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts, 4.5 parts, 5 parts etc..
The composition kit of one or more aspects of the invention, the Prevention and treatment bed body smell can Further to add auxiliary material, the auxiliary material can be antioxidant, bacteriostatic agent, essence or host material etc..
One or more aspects of the invention, the prevention and treatment bed body smell composition kit it is final PH value can be 5.5-7.8, for example, 6.0-7.5, such as be 6.5-7.0.
In the composition kit of one or more aspects of the invention, the prevention and treatment bed body smell:Make a gift of Shellfish soft tissue extract, trypsase and sodium acid carbonate can be dry powder.
In the composition kit of one or more aspects of the invention, the prevention and treatment bed body smell:Make a gift of Shellfish soft tissue extract, trypsase and sodium acid carbonate can be liquid.
One or more aspects of the invention, the mussel soft tissue extract is all in addition to shell with mussel Component is raw material, and the supernatant for being extracted by acidic aqueous solution and being obtained, wherein protein content are 0.2-15.0mg/ml, pH Value 1.0-6.0.Especially, can be with byssus as raw material.
One or more aspects of the invention, the mussel can include Mytilus galloprovincialis, Perna viridis and Trachyostracous mussel In one kind, two or three.
One or more implementation methods of the invention, the acidic aqueous solution can include:Acetic acid-acetate buffer Liquid, acetic acid, citric acid, perchloric acid etc., but not limited to this.
One or more implementation methods of the invention, the protein content of the mussel soft tissue extract can be Such as 0.2mg/ml, 0.3mg/ml, 0.4mg/ml, 0.5mg/ml, 0.6mg/ml, 0.7mg/ml, 0.8mg/ml, 0.9mg/ml, 1.0mg/ml、1.5mg/ml、2.0mg/ml、2.5mg/ml、3.0mg/ml、3.5mg/ml、4.0mg/ml、4.5mg/ml、 5.0mg/ml、5.5mg/ml、6.0mg/ml、6.5mg/ml、7.0mg/ml、7.5mg/ml、8.0mg/ml、8.5mg/ml、 9.0mg/ml、9.5mg/ml、10.0mg/ml、10.5mg/ml、11.0mg/ml、11.5mg/ml、12.0mg/ml、12.5mg/ Ml, 13.0mg/ml, 13.5mg/ml, 14.0mg/ml, 14.5mg/ml and 15.0mg/ml etc., but not limited to this.
One or more aspects of the invention, the trypsase can be conventional purchase from the market.Substitute Ground, the trypsase can be by saltouing, it is prepared by the method such as column chromatography.
Additionally, the present invention also proposes to prevent and treat the pharmaceutical composition kit of bed body smell, contain mussel soft tissue Extract, trypsase, NaHCO3, tea tree ethereal oil and Lavender, optionally, can also be conventional containing other field of medicaments Or acceptable auxiliary material.
The pharmaceutical composition kit of one or more aspects of the invention, the prevention and treatment bed body smell can To be prepared into the forms such as spray, drops, gel, ointment, pulvis.
One or more implementation methods of the invention, the A agent and B agent are to be individually insulated to be present in kit.
One or more implementation methods of the invention, described prevention and the composition kit for the treatment of bed body smell Application method, A agent and B agent can be that order is used or is applied in combination, and preferably can be order of administration.For order of administration For, A agent and B agent can in any order be used.For example, B agent first can be reused using A agent, or can first use B Agent reuses A agent.In whole treatment cycle, both frequency of use can be with identical or different.
In one aspect of the invention, a kind of composition kit for preventing and treating bed body smell, including:
A agent includes:Trypsase 0.1-20 parts,
NaHCO30.1-10 parts;
B agent includes:0.1-15 parts of mussel soft tissue extract,
Tea tree ethereal oil 0.1-5 parts,
Lavender 0.1-5 parts.
Additionally, the present invention also proposes a kind of composition kit for preventing and treating bed body smell, contain mussel soft tissue Extract, trypsase, NaHCO3, tea tree ethereal oil and Lavender, optionally, can also pharmaceutically be commonly used containing other or Acceptable carrier.
One or more aspects of the invention, the carrier can include any and all of solvent, salt, dispersion Medium, coating material, surfactant, antioxidant, preservative (such as antiseptic, antifungal agent), isotonic agent, absorption delay Agent, drug stabilizing agent, adhesive, excipient, disintegrant, lubricant, sweetener, flavouring, dyestuff etc. and they in it is a kind of, many The combination of kind or whole, this is well-known to those skilled in the art (for example, see Remington's Pharmaceutical Sciences,18th Ed.Mack Printing Company,1990,pp.1289-1329).Except with active component not phase Outside the carrier of appearance, it is contemplated that any conventional carrier used in treatment use or pharmaceutical composition.
The pharmaceutical composition kit of prevention of the present invention and treatment bed body smell can be used for preventing and treating people Body peculiar smell, control microorganism infection, for patient provide good effect, treatment cycle it is short, without the product for relying on, having no toxic side effect.
Following examples are illustrated by taking the pharmaceutical composition kit of Prevention and treatment bed body smell as an example, but not It is limited to this, it is various comprising mussel soft tissue extract, trypsase, NaHCO that the invention described above is proposed3, tea tree ethereal oil and The prevention of Lavender and the composition kit for the treatment of bed body smell are applied to the present invention.
Specific embodiment
Embodiment 1:A kind of preparation method of mussel soft tissue extract.
Take mussel to shell, collect soft tissue 300g, be divided into three parts, every part adds the following table acidity of 100ml contents 0.3% molten Liquid, centrifugation obtains supernatant as mussel soft tissue extract after homogenate 10min.
Protein content and pH value in supernatant are determined, determining the protein quantity uses Coomassie Brilliant Blue.
Table 1
Example Acid solution Protein content PH value
1 Citric acid 2.6mg/ml 4.5
2 Acetic acid 3.5mg/ml 3.2
3 Perchloric acid 3.0mg/ml 1.0
Embodiment 2:A kind of composition kit for preventing and treating bed body smell
The composition kit of prevention and treatment bed body smell includes A agent and B agent, and wherein A agent is made up of following components:Pancreas Protease dry powder 13.5mg, NaHCO38mg, above-mentioned substance is dissolved in after water adding and obtain gel in swelling good gel-type vehicle; B agent is made up of following components:Mussel soft tissue extract dry powder 13.5mg, tea tree ethereal oil 3.5mg, Lavender 3.5mg, state Material is dissolved in after water adding and obtain gel in swelling good gel-type vehicle.A agent and B agent are manufactured separately, and are individually packaged in reagent Box.
Selection underarm odor patient 20 and foot odour patient 20, the prevention prepared using embodiment 3 and treatment bed body smell Composition kit, patient first smears A agent in smearing B agent behind affected part, interval 30min in affected part after cleaning affected part daily.Daily Once, it is within two weeks a course for the treatment of.
Using curative effect is judged by smell after a course for the treatment of, criterion of therapeutical effect is:
It is effective:One course for the treatment of terminates rear stink and eliminates, and perspires recovery normal;
Take a turn for the better:Stink symptom has clear improvement;
It is invalid:Symptom is without improvement.
Efficacy result:
Type Case load It is effective Take a turn for the better It is invalid Total effective rate
Underarm odor 20 12 6 2 90%
Foot odour 20 14 5 1 95%
The present invention is respectively 90% and 95% to the total effective rate that underarm odor and foot odour are treated, and illustrates the present invention to bed body smell With obvious therapeutic action.
Embodiment 3:A kind of composition kit for preventing and treating bed body smell
The composition kit of prevention and treatment bed body smell includes A agent and B agent, and wherein A agent is made up of following components:Pancreas Protease dry powder 20mg, NaHCO310mg, above-mentioned substance adds physiological saline to be made spray;B agent is made up of following components:Make a gift of Shellfish soft tissue extract dry powder 15mg, tea tree ethereal oil 5mg, Lavender 5mg, above-mentioned substance add physiological saline to be made spray Agent.A agent and B agent are manufactured separately, and are individually packaged in kit.
Embodiment 4:A kind of application method of the composition kit for preventing and treating bed body smell
The application method of composition kit of prevention and treatment bed body smell is:
1) A agent is first used, B agent is reused after the 30min of interval;
2) B agent is first used, A agent is reused after the 30min of interval;Or
3) used simultaneously after A agent and B agent mixing.
Selection halitosis patient 30, is randomly divided into treatment group 1, treatment group 2 and treatment group 3, and three groups are all made using embodiment 3 Standby prevention and the composition kit for the treatment of bed body smell, but application method is different, and treatment group 1 is first sprayed on using A agent daily Oral cavity, oral cavity is sprayed on after the 30min of interval using B agent, daily to use once, is within two weeks a course for the treatment of;Treatment group 2 first uses daily B agent is sprayed on oral cavity, and oral cavity is sprayed on using A agent after the 30min of interval, daily to use once, is within two weeks a course for the treatment of;Treatment group 3 is by A Oral cavity is sprayed on after agent and B agent mixing, it is daily to use once, it is within two weeks a course for the treatment of.
Using curative effect is judged by smell after a course for the treatment of, criterion of therapeutical effect is:
Recovery from illness:There is not peculiar smell after terminating in one course for the treatment of;
It is effective:One course for the treatment of terminates rear peculiar smell and substantially mitigates, and slight peculiar smell is just only smelt when body is pressed close to;
Effectively:One course for the treatment of terminates rear peculiar smell and mitigates, and is restored to the original state again after drug withdrawal;
It is invalid:One course for the treatment of terminates rear peculiar smell without change.
After one course for the treatment of, efficacy result such as table 2.
Group Recovery from illness It is effective Effectively It is invalid It is efficient
Treatment group 1 8 1 1 0 100%
Treatment group 2 6 2 1 1 90%
Treatment group 3 5 2 1 2 80%
Clinical test shows that three kinds of application methods of the kit that the embodiment of the present invention 4 is proposed are to treatment bed body smell There is remarkable result, and it was found that more preferable than other two kinds of application method effects using the application method of B agent using 30min after A agent.
Certainly, the present invention can also have other various embodiments, ripe in the case of without departing substantially from spirit of the invention and its essence Knowing those skilled in the art can make various corresponding changes and deformation, but these corresponding changes and deformation according to the present invention The protection domain of the claims in the present invention should all be belonged to.

Claims (9)

1. it is a kind of prevent and treatment bed body smell composition kit, it is characterised in that the prevention and treatment bed body smell Composition kit include A agent and B agent, wherein, based on composition total weight, the A agent includes:Trypsase 0.1-20 Part, NaHCO30.1-10 parts;The B agent includes 0.1-15 parts of mussel soft tissue extract, tea tree ethereal oil 0.1-5 parts, lavender Essential oil 0.1-5 parts.
2. prevention according to any preceding claims and the composition kit for the treatment of bed body smell, it is characterised in that It is described to prevent and treat the composition kit of bed body smell based on composition total weight, wherein, the A agent includes:Tryptose Enzyme is such as 0.1 part, 0.2 part, 1 part, 1.5 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts, 4.5 parts, 5 parts, 5.5 parts, 6 parts, 6.5 Part, 7 parts, 7.5 parts, 8 parts, 8.5 parts, 9 parts, 9.5 parts, 10 parts, 10.5 parts, 11 parts, 11.5 parts, 12 parts, 12.5 parts, 13 parts, 13.5 parts, 14 parts, 14.5 parts, 15 parts, 15.5 parts, 16 parts, 16.5 parts, 17 parts, 17.5 parts, 18 parts, 18.5 parts, 19 parts, 19.5 Part, 20 parts, NaHCO3Such as 0.1 part, 0.2 part, 1 part, 1.5 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts, 4.5 parts, 5 parts, 5.5 parts, 6 parts, 6.5 parts, 7 parts, 7.5 parts, 8 parts, 8.5 parts, 9 parts, 9.5 parts, 10 parts;The B agent includes:Mussel soft tissue is extracted Thing is such as 0.1 part, 1 part, 1.5 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts, 4.5 parts, 5 parts, 5.5 parts, 6 parts, 6.5 parts, 7 Part, 7.5 parts, 8 parts, 8.5 parts, 9 parts, 9.5 parts, 10 parts, 10.5 parts, 11 parts, 11.5 parts, 12 parts, 12.5 parts, 13 parts, 13.5 parts, 14 parts, 14.5 parts, 15 parts, tea tree ethereal oil is such as 0.1 part, 1 part, 1.5 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts, 4.5 parts, 5 parts, Lavender is such as 0.1 part, 1 part, 1.5 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts, 4.5 parts, 5 parts.
3. prevention according to any preceding claims and the composition kit for the treatment of bed body smell, it is characterised in that The composition kit further includes auxiliary material, such as antioxidant, bacteriostatic agent, essence or host material;Or described group Compound further includes pharmaceutically acceptable carrier, solvent such as, salt, decentralized medium, coating material, surfactant, Antioxidant, preservative (such as antiseptic, antifungal agent), isotonic agent, absorption delaying agent, drug stabilizing agent, adhesive, figuration Agent, disintegrant, lubricant, sweetener, flavouring, dyestuff and combination a kind of, various or whole in them.
4. prevention according to any preceding claims and the composition kit for the treatment of bed body smell, it is characterised in that The composition final ph soluble in water is 5.5-7.8.
5. prevention according to any preceding claims and the composition kit for the treatment of bed body smell, it is characterised in that The mussel soft tissue extract, trypsase and sodium acid carbonate are dry powder or liquid.
6. prevention according to any preceding claims and the composition kit for the treatment of bed body smell, it is characterised in that The mussel soft tissue extract is the component raw material with mussel in addition to shell, is extracted by acidic aqueous solution, is taken after centrifugation What supernatant was obtained, wherein protein content 0.2-15.0mg/ml, pH value 1.0-6.0.
7. it is according to claim 7 prevention and treatment bed body smell composition kit, wherein the acidic aqueous solution Including:Acetic acid-sodium acetate buffer solution, acetic acid, citric acid, perchloric acid, or wherein described mussel soft tissue extract albumen Matter content be, for example, 0.2mg/ml, 0.3mg/ml, 0.4mg/ml, 0.5mg/ml, 0.6mg/ml, 0.7mg/ml, 0.8mg/ml, 0.9mg/ml、1.0mg/ml、1.5mg/ml、2.0mg/ml、2.5mg/ml、3.0mg/ml、3.5mg/ml、4.0mg/ml、 4.5mg/ml、5.0mg/ml、5.5mg/ml、6.0mg/ml、6.5mg/ml、7.0mg/ml、7.5mg/ml、8.0mg/ml、 8.5mg/ml、9.0mg/ml、9.5mg/ml、10.0mg/ml、10.5mg/ml、11.0mg/ml、11.5mg/ml、12.0mg/ml、 12.5mg/ml, 13.0mg/ml, 13.5mg/ml, 14.0mg/ml, 14.5mg/ml and 15.0mg/ml;Or the mussel includes One kind in Mytilus galloprovincialis, Perna viridis, Trachyostracous mussel, two or three.
8. prevention according to any preceding claims and the composition kit for the treatment of bed body smell, it is characterised in that The composition is the form of spray, drops, gel, ointment, pulvis.
9. prevention according to any preceding claims and the composition kit for the treatment of bed body smell, it is characterised in that The A agent and B agent are to be applied in combination or order is used.
CN201611264444.1A 2016-12-30 2016-12-30 Composition kit for preventing and curing peculiar smells of human bodies and using method thereof Withdrawn CN106668849A (en)

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