CN106620636A - 一种治疗腰痛的药物及其制备方法 - Google Patents
一种治疗腰痛的药物及其制备方法 Download PDFInfo
- Publication number
- CN106620636A CN106620636A CN201710136441.8A CN201710136441A CN106620636A CN 106620636 A CN106620636 A CN 106620636A CN 201710136441 A CN201710136441 A CN 201710136441A CN 106620636 A CN106620636 A CN 106620636A
- Authority
- CN
- China
- Prior art keywords
- grams
- gram
- dried
- impurity
- picked
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/586—Turtles; Tortoises, e.g. terrapins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/487—Psoralea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/732—Chaenomeles, e.g. flowering quince
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/746—Morinda
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种治疗腰痛的药物及其制备方法,其是由黄芪、当归、川芎、赤芍、熟地黄、升麻、乌药、蚯蚓、补骨脂、续断、菟丝子、防风、独活、巴戟天、茯苓、桑寄生、秦艽、龟版、山药、白术、川牛膝、黄柏、狗脊、苍术、干姜、木瓜按一定重量配比制备而成,本发明药物具有行气开郁,祛风燥湿,活血止痛,清热凉血,补肾助阳,散寒止痛的功能,用于治疗腰痛见效快、疗效好,不复发。
Description
技术领域
本发明涉及一种治疗腰痛的药物及其制备方法,属中药领域。
背景技术
腰痛是指因外感、内伤或挫闪导致腰部气血运行不畅,或失于濡养,引起腰脊或脊旁部位疼痛为主要症状的一种病证。其发病常以肾虚为本,感受外邪、跌仆挫闪为标。治疗时实证重在祛邪通脉活络,虚证重在扶正,补肝肾、强腰膝、健脾气是常用治法。由于西药治疗副作用大,因此人们对有效治疗腰痛的中药药物存在极大的需求,至今为止,还没有发现关于本发明的有关报道。
发明内容
本发明人依据中医理论的研究和临床试验的反复验证,终于找到了有效治疗腰痛的药物,从而完成了本发明。
本发明的目的就是提供一种有效治疗腰痛的中药组合药物。
本发明的另一目的就是提供了该中药组合药物的制备方法。
本发明药物是选择黄芪、当归、川芎、赤芍、熟地黄、升麻、乌药、蚯蚓、补骨脂、续断、菟丝子、防风、独活、巴戟天、茯苓、桑寄生、秦艽、龟版、山药、白术、川牛膝、黄柏、狗脊、苍术、干姜、木瓜进行组合制备的,将这些药物组合使得各药物功效产生协同作用,从而能够有效治疗腰痛。其中选用黄芪是因为其性味甘,微温,入肺、脾经,生用有益卫固表,利水消肿,托毒,生肌的功能,治自汗,盗汗,血痹,浮肿,痈疽不溃或溃久敛;炙用有补中益气的功能,治内伤劳倦,脾虚泄泻,脱肛,气虚血脱,崩带及一切气衰血虚之症。选用当归是因为其性味甘辛,温,入心、肝、脾经,有补血和血,调经止痛,润燥滑肠的功能,治***,经闭腹痛,癥瘕结聚,崩漏,血虚头痛,眩晕,痿痹,肠燥难便,赤痢后重,痈疽疮疡,金疮,跌扑损伤。选用川芎是因为其性味辛,温,入肝、胆经,有行气开郁,祛风燥湿,活血止痛的功能,治风冷头痛旋晕,胁痛腹疼,寒痹筋挛,经闭,难产,产后瘀阻块痛,痈疽疮疡。选用赤芍是因为其性味苦,微寒,归肝经,有清热凉血,散瘀止痛的功能,治温毒发狂,吐血衄血,目赤肿痛,肝郁胁痛,经闭痛经,癎瘕腹痛,跌扑损伤,痈肿疮疡。选用熟地黄是因为其性味甘,微温,入肝、肾经,有滋阴,补血的功能,治阴虚血少,腰膝痿弱,劳嗽骨蒸,遗精,崩漏,***,消渴,溲数,耳聋,目昏。选用升麻是因为其性味甘辛微苦,凉,入肺、脾、胃经,有升阳,发表,透疹,解毒的功能,治时气疫劳,头痛寒热,喉痛,口疮疤,斑疹不透,中气下陷,久泻久痢,脱肛,妇女崩带,子宫下坠,痈肿疮毒。选用乌药是因为其性味辛,温,入脾、肺、肾、膀胱经,有顺气,开郁,散寒,止痛的功能,治气逆胸腹胀痛,宿食不满,反胃吐食,寒疝,脚气,小便频数。选用蚯蚓是因为其性味咸,寒,入肝、脾、肺经,有清热,平肝,止喘,通络的功能,治高热狂躁,惊风抽搐,风热头痛,目赤,中风半身不遂,喘息,喉痹,关节疼痛,齿衄,小便不通,瘰疬,痄腮,疮疡。选用补骨脂是因为其性味辛,温,入肾经,有补肾助阳的功能,治肾虚冷泻,遗尿,滑精,小便频数,阳痿,腰膝冷痛,虚寒喘嗽,外用治白癜风。选用续断是因为其性味苦辛,微温,入肝、肾经,有补肝肾,续筋骨,调血脉的功能,治腰背酸痛,足膝无力,胎漏,崩漏,带下,遗精,跌打损伤,金疮,痔漏,痈疽疮肿。选用菟丝子是因为其性味辛甘,平,入肝、肾经,有补肝肾,益精髓,明目的功能,治腰膝酸痛,遗精,消渴,尿有余沥,目暗。选用防风是因为其性味辛甘,温,入膀胱、肺、脾经,有发表,祛风,胜湿,止痛的功能,治外感风寒,头痛,目眩,项强,风寒湿痹,骨节酸痛,四肢挛急,破伤风。选用独活是因为其性味辛苦,温,入肾、膀胱经,有祛风,胜湿,散寒,止痛的功能,治风寒湿痹,腰漆酸痛,手脚挛痛,慢性气管炎,头痛,齿痛。选用巴戟天是因为其性味辛甘,温,入肝、肾经,有补肾阳,壮筋骨,祛风湿的功能,治阳痿,少腹冷痛,小便不禁,子宫虚冷,风寒湿痹,腰膝酸痛。选用茯苓是因为其性味甘淡,平,入心、脾、肺经,有渗湿利水,益脾和胃,宁心安神的功能,治小便不利水肿胀痛,痰饮咳逆,呕哕,泄泻,遗精,淋浊,惊悸,健忘。选用桑寄生是因为其性味苦甘,平,入肝、肾经,有补肝肾,强筋骨,除风湿,通经络,益血,安胎的功能,治腰膝酸痛,筋骨痿弱,偏枯,脚气,风寒湿痹,胎漏血崩,产后乳汁不下。选用秦艽是因为其性味苦辛,平,入肝、胃、胆经,有祛风除湿,和血舒筋,清热利尿的功能,治风湿痹痛,筋骨拘挛,黄疸,便血,骨蒸潮热,小儿疳热,小便不利。选用龟版胶是因为其性味甘咸,平,有滋阴,补血,止血的功能,治阴虚血亏,劳热骨蒸,吐血,衄血,烦热惊悸,肾虚腰痛,脚膝痿弱,崩漏,带下。选用山药是因为其性味甘,平,入肺、脾、肾经,有健脾,补肺,固肾,益精的功能,治脾虚泄泻,久痢,虚劳咳嗽,消渴,遗精、带下,小便频数。选用白术是因为其性味苦甘,温,入脾、胃经,有补脾,益胃,燥湿,和中的功能,治脾胃气弱,不思饮食,倦怠少气,虚胀,泄泻,痰饮,水肿,黄疸,湿痹,小便不利,头晕,自汗,胎气不安。选用川牛膝是因为其性味平,味苦微苦,无毒,入肝、肾二经,有祛风,利湿,通经,活血的功能,治风湿腰膝疼痛,脚痿筋挛,血淋,尿血,妇女经闭,癥瘕。选用黄柏是因为其性味苦,寒,入肺、胃、肾经,有滋阴降火,润燥滑肠的功能,治烦热消渴,骨蒸劳热,肺热咳嗽,大便燥结,小便不利。选用狗脊是因为其性味苦甘,温,入肝、肾经,有补肝肾,除风湿,健腰脚,利关节的功能,治腰背酸疼,膝痛脚弱,寒湿周痹,失溺,尿频,遗精,白带。选用苍术是因为其性味辛苦,温,入脾、胃经,有健脾,燥湿,解郁,辟秽的功能,治湿盛困脾,倦怠嗜卧,脘痞腹胀,食欲不振,呕吐,泄泻,痢疾,疟疾,痰饮,水肿,时气感冒,风寒湿痹,足痿,夜盲。选用干姜是因为其性味辛,热,入脾、胃、肺经,有温中逐寒,回阳通脉的功能,治心腹冷痛,吐泻,肢冷脉微,寒饮喘咳,风寒湿痹,阳虚吐、衄、下血。选用木瓜是因为其性味酸,温,入肝、脾经,有平肝和胃,去湿舒筋的功能,治吐泻转筋,湿痹,脚气,水肿,痢疾。
具体实施方式
本发明组分的药物用量也是发明人经过大量摸索总结得出的,各组分的用量在下述重量范围内都具有较好的疗效:
黄芪15-25克,当归10-14克,川芎6-10克,赤芍5-15克,熟地黄24-28克,升麻5-15克,乌药5-15克,蚯蚓5-15克,补骨脂5-15克,续断5-15克,菟丝子5-15克,防风5-15克,独活5-15克,巴戟天5-15天,茯苓5-15克,桑寄生10-20克,秦艽10-14克,龟版10-20克,山药10-20克,白术5-15克,川牛膝10-20克,黄柏5-15克,狗脊5-15克,苍术5-15克,干姜5-15克,木瓜10-14克。
优选为:
黄芪20克,当归12克,川芎8克,赤芍10克,熟地黄26克,升麻10克,乌药10克,蚯蚓10克,补骨脂10克,续断10克,菟丝子10克,防风10克,独活10克,巴戟天10天,茯苓10克,桑寄生15克,秦艽12克,龟版15克,山药15克,白术10克,川牛膝15克,黄柏10克,狗脊10克,苍术10克,干姜10克,木瓜12克。
本发明药物的制备方法如下
一、备料
1、黄芪:拣净杂质,除去残留的根头和空心较大的根,用水浸泡,捞出,润透后及时切片,晒干;
2、当归:拣去杂质,洗净,闷润,稍晾,切片晒干;
3、川芎:拣去杂质,分开大、小个,用水浸泡,晒晾,闷润后切片,干燥;
4、赤芍:取原药材,除去杂质,大小分档,洗净,润透,切薄片,干燥,筛去碎屑;
5、熟地黄:取原药材,蒸至表面乌黑色,取出,晒至八成干时,切片,干燥;
6、升麻:拣去杂质,略泡洗净,捞出,润透,切片,晒干;
7、乌药:拣去杂质,分开大小条,用水泡透,根据季节注意换水,防止发臭,及时捞出切片,筛去灰屑;
8、蚯蚓:拣去杂质,用水漂净,及时捞出,晒干,切段;
9、补骨脂:簸净杂质,洗净,晒干;
10、续断:洗净泥沙,除去残留根头,润透后切片晒干,筛去屑;
11、菟丝子:过箩去净杂质,洗净,晒干;
12、防风:除去残茎,用水浸泡,捞出,润透切片,晒干;
13、独活:拣去杂质,分开大小个,洗净,润透后切片,干燥;
14、巴戟天:拣去杂质,用热水泡透后,趁热抽去木心,切段,晒干;
15、茯苓:用水浸泡,洗净捞出,闷透后,切片,晒干;
16、桑寄生:用水洗净,润透,切段,晒干;
17、秦艽:拣去杂质,除去芦头,稍浸,润透切片,晒干;
18、龟版:用清水浸泡,刮去残肉,洗净晒干,敲成小块;
19、山药:拣净杂质,用水浸泡至山药中心部软化为止,捞出稍晾,切片晒干或烘干;
20、白术:拣净杂质,用水浸泡,泡后捞出,润透,切片,晒干;
21、川牛膝:拣去杂质,晾干;
22、黄柏:拣去杂质,用水洗净,捞出,润透,切片或切丝,晒干;
23、狗脊:取沙子置锅内炒至轻松,加入拣净的狗脊,用武火炒至鼓起并显深黄色,取出,筛除沙子,风晾后,撞去或刮净黄绒毛;
24、苍术:拣去杂质,用水泡至七、八成透,捞出,润透后切片,晒干;
25、干姜:拣净杂质,用水浸泡3—6小时,捞出,闷润后切片或切成小方块,晒干;
26、木瓜:清水洗净,稍浸泡,闷润至透,置蒸笼内蒸熟,趁热切片,日晒夜露,以由红转紫黑色为止。
二、制备
1、将所述重量的黄芪、当归、川芎、赤芍、熟地黄、升麻、乌药、蚯蚓、补骨脂、续断、菟丝子、防风、独活、巴戟天、茯苓、桑寄生、秦艽、龟版、山药、白术、川牛膝、黄柏、狗脊、苍术、干姜、木瓜放入煎药容器内,加水8倍量,浸泡120分钟后,武火煎煮沸腾,再用文火煎煮20分钟,过滤得第一次煎煮液,将第一次煎煮液倒入容器内;
2、将过滤的药渣加水6倍量,武火煮沸,再用文火煎煮20分钟,过滤得第二次煎煮液;
3、将两次煎煮液混合搅拌均匀,分为3剂服用。
组方中川芎有行气开郁,祛风燥湿,活血止痛的功能为君药;赤芍有清热凉血,散瘀止痛的功能;补骨脂有补肾助阳的功能,二者为臣药,三味药共同发挥行气开郁,祛风燥湿,活血止痛,清热凉血,补肾助阳的作用,治疗腰痛效力全面,且以行气开郁,活血止痛,补肾助阳为主可治本,菟丝子有补肝肾,益精髓的功能为佐药,独活有祛风,胜湿,散寒,止痛的功能为使药,与下余诸药是治标。
本发明药物具有行气开郁,祛风燥湿,活血止痛,清热凉血,补肾助阳,散寒止痛的功能,用于治疗腰痛,疗程短、见效快、治愈后不复发。
以下通过试验例来进一步阐述本发明所述药物的有益效果,这些试验例包括本发明药物的动物毒性试验报告和临床疗效观察资料。
[试验例1]本发明药物的动物毒性试验报告:
取家兔30只,雌雄兼用,体重2.0—2.5kg,分两组,每组15只,其中一组为超剂量试验组,另一组为正常量试验组。超常量组为20ml/kg,正常量为10ml/kg,给药方式为灌胃法给药,每天两次,连服7天,每天观察给药反应,结果表明二组家兔活动、饮食正常,药物无不良毒副作用。
[试验例2]本发明药物的临床疗效观察
1、一般资料
收治腰痛门诊患者共35例。
2、诊断标准
急性腰痛,病程较短,轻微活动即可引起一侧或两侧腰部疼痛加重,脊柱两旁常有明显的按压痛。慢性腰痛,病程较长,缠绵难愈,腰部多隐痛或酸痛。常因***不当,劳累过度,天气变化等因素而加重。
3、治疗方法
选用上述药剂,给患者服用,每次服用1剂,每天早、晚各服1次,10天为一个疗程,连续服用3个疗程。
4、疗效评定标准
显效:腰痛症状消失,恢复正常,痊愈;
好转:腰痛症状明显好转,疼痛、压痛症状减轻,症状逐步恢复正常;
无效:达不到好转标准者。
5、治疗结果(见下表)
在上述治疗中,用本发明药物治疗腰痛患者35例,结果显效28例,显效率为80%,好转5例,好转率为14.3%,无效2例,总有效率为94.3%。
Claims (3)
1.一种治疗腰痛的药物,其特征在于:它是由下列重量范围内的原料药制成:
黄芪15-25克,当归10-14克,川芎6-10克,赤芍5-15克,熟地黄24-28克,升麻5-15克,乌药5-15克,蚯蚓5-15克,补骨脂5-15克,续断5-15克,菟丝子5-15克,防风5-15克,独活5-15克,巴戟天5-15天,茯苓5-15克,桑寄生10-20克,秦艽10-14克,龟版10-20克,山药10-20克,白术5-15克,川牛膝10-20克,黄柏5-15克,狗脊5-15克,苍术5-15克,干姜5-15克,木瓜10-14克。
2.根据权利要求1所述的药物,其中各原料药的用量为:
黄芪20克,当归12克,川芎8克,赤芍10克,熟地黄26克,升麻10克,乌药10克,蚯蚓10克,补骨脂10克,续断10克,菟丝子10克,防风10克,独活10克,巴戟天10天,茯苓10克,桑寄生15克,秦艽12克,龟版15克,山药15克,白术10克,川牛膝15克,黄柏10克,狗脊10克,苍术10克,干姜10克,木瓜12克。
3.根据权利要求1或2所述药物的制备方法,它包括下列步骤:
(一)备料
(1)黄芪:拣净杂质,除去残留的根头和空心较大的根,用水浸泡,捞出,润透后及时切片,晒干;
(2)当归:拣去杂质,洗净,闷润,稍晾,切片晒干;
(3)川芎:拣去杂质,分开大、小个,用水浸泡,晒晾,闷润后切片,干燥;
(4)赤芍:取原药材,除去杂质,大小分档,洗净,润透,切薄片,干燥,筛去碎屑;
(5)熟地黄:取原药材,蒸至表面乌黑色,取出,晒至八成干时,切片,干燥;
(6)升麻:拣去杂质,略泡洗净,捞出,润透,切片,晒干;
(7)乌药:拣去杂质,分开大小条,用水泡透,根据季节注意换水,防止发臭,及时捞出切片,筛去灰屑;
(8)蚯蚓:拣去杂质,用水漂净,及时捞出,晒干,切段;
(9)补骨脂:簸净杂质,洗净,晒干;
(10)续断:洗净泥沙,除去残留根头,润透后切片晒干,筛去屑;
(11)菟丝子:过箩去净杂质,洗净,晒干;
(12)防风:除去残茎,用水浸泡,捞出,润透切片,晒干;
(13)独活:拣去杂质,分开大小个,洗净,润透后切片,干燥;
(14)巴戟天:拣去杂质,用热水泡透后,趁热抽去木心,切段,晒干;
(15)茯苓:用水浸泡,洗净捞出,闷透后,切片,晒干;
(16)桑寄生:用水洗净,润透,切段,晒干;
(17)秦艽:拣去杂质,除去芦头,稍浸,润透切片,晒干;
(18)龟版:用清水浸泡,刮去残肉,洗净晒干,敲成小块;
(19)山药:拣净杂质,用水浸泡至山药中心部软化为止,捞出稍晾,切片晒干或烘干;
(20)白术:拣净杂质,用水浸泡,泡后捞出,润透,切片,晒干;
(21)川牛膝:拣去杂质,晾干;
(22)黄柏:拣去杂质,用水洗净,捞出,润透,切片或切丝,晒干;
(23)狗脊:取沙子置锅内炒至轻松,加入拣净的狗脊,用武火炒至鼓起并显深黄色,取出,筛除沙子,风晾后,撞去或刮净黄绒毛;
(24)苍术:拣去杂质,用水泡至七、八成透,捞出,润透后切片,晒干;
(25)干姜:拣净杂质,用水浸泡3—6小时,捞出,闷润后切片或切成小方块,晒干;
(26)木瓜:清水洗净,稍浸泡,闷润至透,置蒸笼内蒸熟,趁热切片,日晒夜露,以由红转紫黑色为止;
(二)制备
(1)将所述重量的黄芪、当归、川芎、赤芍、熟地黄、升麻、乌药、蚯蚓、补骨脂、续断、菟丝子、防风、独活、巴戟天、茯苓、桑寄生、秦艽、龟版、山药、白术、川牛膝、黄柏、狗脊、苍术、干姜、木瓜放入煎药容器内,加水8倍量,浸泡120分钟后,武火煎煮沸腾,再用文火煎煮20分钟,过滤得第一次煎煮液,将第一次煎煮液倒入容器内;
(2)将过滤的药渣加水6倍量,武火煮沸,再用文火煎煮20分钟,过滤得第二次煎煮液;
(3)将两次煎煮液混合搅拌均匀,分为3剂服用。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710136441.8A CN106620636A (zh) | 2017-03-09 | 2017-03-09 | 一种治疗腰痛的药物及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710136441.8A CN106620636A (zh) | 2017-03-09 | 2017-03-09 | 一种治疗腰痛的药物及其制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN106620636A true CN106620636A (zh) | 2017-05-10 |
Family
ID=58848193
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710136441.8A Withdrawn CN106620636A (zh) | 2017-03-09 | 2017-03-09 | 一种治疗腰痛的药物及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106620636A (zh) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103735934A (zh) * | 2014-01-26 | 2014-04-23 | 王莉 | 一种治疗腰部疼痛的药物及其制备方法 |
CN105169312A (zh) * | 2015-09-07 | 2015-12-23 | 孙太辉 | 一种治疗腰痛的药物及其制备方法 |
-
2017
- 2017-03-09 CN CN201710136441.8A patent/CN106620636A/zh not_active Withdrawn
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103735934A (zh) * | 2014-01-26 | 2014-04-23 | 王莉 | 一种治疗腰部疼痛的药物及其制备方法 |
CN105169312A (zh) * | 2015-09-07 | 2015-12-23 | 孙太辉 | 一种治疗腰痛的药物及其制备方法 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN106075247A (zh) | 一种治疗慢性尿潴留的药物及其制备方法 | |
CN107823402A (zh) | 一种治疗阳痿的药物及其制备方法 | |
CN104056224A (zh) | 一种治疗习惯性流产的药物及其制备方法 | |
CN103638464A (zh) | 一种治疗慢性肝炎的药物及其制备方法 | |
CN106620636A (zh) | 一种治疗腰痛的药物及其制备方法 | |
CN106692858A (zh) | 一种治疗胎动不安的药物及其制备方法 | |
CN107714907A (zh) | 一种治疗阳瘘的药物及其制备方法 | |
CN106902343A (zh) | 一种治疗坐骨神经痛的药物及其制备方法 | |
CN106822554A (zh) | 一种治疗***炎的药物及其制备方法 | |
CN106620362A (zh) | 一种治疗乳糜尿的药物及其制备方法 | |
CN106822534A (zh) | 一种治疗***的药物及其制备方法 | |
CN106729118A (zh) | 一种治疗肾盂肾炎的药物及其制备方法 | |
CN106729057A (zh) | 一种治疗鼻衄的药物及其制备方法 | |
CN105381409A (zh) | 一种治疗胆石症的药物及其制备方法 | |
CN105169312A (zh) | 一种治疗腰痛的药物及其制备方法 | |
CN104436124A (zh) | 一种治疗阑尾炎的药物及其制备方法 | |
CN107737293A (zh) | 一种治疗女性***症的药物及其制备方法 | |
CN103830698A (zh) | 一种治疗儿童***的药物及其制备方法 | |
CN106798860A (zh) | 一种治疗脊髓灰质炎的药物及其制备方法 | |
CN106692794A (zh) | 一种治疗下肢溃疡的药物及其制备方法 | |
CN108283693A (zh) | 一种治疗慢性肠炎的药物及其制备方法 | |
CN107823530A (zh) | 一种治疗遗精的药物及其制备方法 | |
CN108743902A (zh) | 一种治疗低血压的药物及其制备方法 | |
CN108785607A (zh) | 一种治疗类风湿关节炎的药物及其制备方法 | |
CN108261494A (zh) | 一种治疗***炎的药物及其制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WW01 | Invention patent application withdrawn after publication |
Application publication date: 20170510 |
|
WW01 | Invention patent application withdrawn after publication |