CN106539701A - A kind of gel containing silk essence and preparation method thereof - Google Patents

A kind of gel containing silk essence and preparation method thereof Download PDF

Info

Publication number
CN106539701A
CN106539701A CN201611052675.6A CN201611052675A CN106539701A CN 106539701 A CN106539701 A CN 106539701A CN 201611052675 A CN201611052675 A CN 201611052675A CN 106539701 A CN106539701 A CN 106539701A
Authority
CN
China
Prior art keywords
parts
silk essence
containing silk
polyethylene glycol
essence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201611052675.6A
Other languages
Chinese (zh)
Inventor
汪屹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangsu Love Beauty Technology Advisory Services Ltd By Share Ltd
Original Assignee
Jiangsu Love Beauty Technology Advisory Services Ltd By Share Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Love Beauty Technology Advisory Services Ltd By Share Ltd filed Critical Jiangsu Love Beauty Technology Advisory Services Ltd By Share Ltd
Priority to CN201611052675.6A priority Critical patent/CN106539701A/en
Publication of CN106539701A publication Critical patent/CN106539701A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/736—Chitin; Chitosan; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89—Polysiloxanes
    • A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

The invention provides a kind of gel containing silk essence and preparation method thereof, the gel includes：Silk essence, the different monooctyl ester of ESCAROL 507, methyl parahydroxybenzoate, glycerol, shitosan, glyceryl monostearate, Propylene Glycol, citric acid, Polyethylene Glycol, butanediol, hyaluronate sodium, polydimethylsiloxane and deionized water.Its preparation method is first by ESCAROL 507 different monooctyl ester, methyl parahydroxybenzoate, glycerol; Propylene Glycol; citric acid, Polyethylene Glycol, butanediol and hyaluronate sodium are added in reactor; under conditions of inert gas shielding; heat up, be subsequently adding remaining ingredient, heated and stirred; stand after cooling, obtain the gel containing silk essence.The gel of the present invention has good water absorption, water penetration, poisture-penetrability and good biocompatibility, can keep the wettability of skin.

Description

A kind of gel containing silk essence and preparation method thereof
Technical field
The invention belongs to cosmetics of everyday use preparing technical field, and in particular to a kind of gel containing silk essence and its preparation side Method.
Background technology
Silk essence is, using modern biochemical technology, fibroin albumen to be hydrolyzed to after a certain proportion of polypeptide and aminoacid, then Jing The aminoacids complex and dipeptides, the mixture of tripeptides of natural silk obtained by purifying and refining.Contain certain molecular weight in silk essence The water-soluble fibroin polypeptide with physiologically active (dipeptides and tripeptides), be easily absorbed by the body, to degrade blood of human body in blood Sugar and cholesterol etc. are with certain health care prevention function.Silk essence has remarkable performance of keeping humidity, contained free multiple in silk essence Closing aminoacid and low-molecular-weight dipeptides and tripeptides has good affinity with human body skin and hair, can penetrate skin and hair Horny layer reach inside which, there is provided abundant nutritional labeling, in skin-care cosmetics add silk essence when, silk essence oligopeptide May penetrate into the horny layer of skin, and participate in the activity of internal enzyme, assimilated and absorbed by skin quickly, reach skin protection, skin moistening and Effect of foster skin.Silk essence has extensive in food and medicine health care and cosmetics with its excellent physiologically active peptide feature Application prospect.Silk essence is considerably less for cosmetics of everyday use series of products at present, it is therefore desirable to develops a kind of skin protection containing silk essence and produces Product, and then expand its application.
The content of the invention
The purpose of the present invention is to overcome the deficiencies in the prior art and provide a kind of gel containing silk essence and preparation method thereof, Gained gel has good water absorption, water penetration, poisture-penetrability and good biocompatibility.
A kind of gel containing silk essence, including following component in parts by weight：Silk essence 5-10 parts, to dimethylamino benzene The different monooctyl ester 1-3 parts of formic acid, methyl parahydroxybenzoate 2-4 parts, glycerol 2-3 parts, shitosan 0.1-0.4 parts, monostearate are sweet Grease 0.3-0.5 parts, Propylene Glycol 0.5-1 part, citric acid 0.1-0.3 parts, Polyethylene Glycol 1-3 parts, butanediol 1-2 parts, hyalomitome Sour sodium 1-3 parts, polydimethylsiloxane 0.3-0.5 parts, deionized water 45-60 parts.
Further, Polyethylene Glycol is Macrogol 600.
The preparation method of the above-mentioned gel containing silk essence, comprises the following steps：
Step one, weighs each component according to weight portion；
Step 2, by ESCAROL 507 different monooctyl ester, methyl parahydroxybenzoate, glycerol, Propylene Glycol, Fructus Citri Limoniae Acid, Polyethylene Glycol, butanediol and hyaluronate sodium are added in reactor, under conditions of inert gas shielding, are warming up to 50- 60 DEG C, kept for 10-20 minutes, obtain mixture one；
Step 3, remaining ingredient is added in mixture one, is heated to 50-60 DEG C, is stirred 5-10 minutes, is then lowered the temperature To 4 DEG C, stand and keep 3-5h, obtain the gel containing silk essence.
Further, in step 2, noble gases are nitrogen or argon.
Further, the process for 50-60 DEG C being warming up in step 2 is to be warming up to 50-60 with 3-5 DEG C/min of speed ℃。
Further, it is to be cooled to 4 DEG C with 5-6 DEG C/min of speed that 4 DEG C are cooled in step 3.
The gel of the present invention has good water absorption, water penetration, poisture-penetrability and good biocompatibility, can keep The wettability of skin.
Specific embodiment
Embodiment 1
A kind of gel containing silk essence, including following component in parts by weight：5 parts of silk essence, to dimethylamino benzene first 1 part of the different monooctyl ester of acid, 2 parts of methyl parahydroxybenzoate, 2 parts of glycerol, 0.1 part of shitosan, 0.3 part of glyceryl monostearate, third 0.5 part of glycol, 0.1 part of citric acid, 1 part of Polyethylene Glycol, 1 part of butanediol, 1 part of hyaluronate sodium, polydimethylsiloxane 0.3 Part, 45 parts of deionized water.
Wherein, Polyethylene Glycol is Macrogol 600.
The preparation method of the above-mentioned gel containing silk essence, comprises the following steps：
Step one, weighs each component according to weight portion；
Step 2, by ESCAROL 507 different monooctyl ester, methyl parahydroxybenzoate, glycerol, Propylene Glycol, Fructus Citri Limoniae Acid, Polyethylene Glycol, butanediol and hyaluronate sodium are added in reactor, under conditions of inert gas shielding, are warming up to 50- 60 DEG C, kept for 10-20 minutes, obtain mixture one；
Step 3, remaining ingredient is added in mixture one, is heated to 50-60 DEG C, is stirred 5-10 minutes, is then lowered the temperature To 4 DEG C, stand and keep 3-5h, obtain the gel containing silk essence.
Wherein, in step 2, noble gases are nitrogen or argon, and the process for being warming up to 50-60 DEG C is with 3-5 DEG C/min Speed is warming up to 50-60 DEG C；It is to be cooled to 4 DEG C with 5-6 DEG C/min of speed that 4 DEG C are cooled in step 3.
Embodiment 2
A kind of gel containing silk essence, including following component in parts by weight：6 parts of silk essence, to dimethylamino benzene first 1.6 parts of the different monooctyl ester of acid, 2.5 parts of methyl parahydroxybenzoate, 2.2 parts of glycerol, 0.2 part of shitosan, glyceryl monostearate 0.4 Part, 0.7 part of Propylene Glycol, 0.2 part of citric acid, 1.4 parts of Polyethylene Glycol, 1.6 parts of butanediol, 1.5 parts of hyaluronate sodium, poly dimethyl 0.4 part of siloxanes, 50 parts of deionized water.
Wherein, Polyethylene Glycol is Macrogol 600.
The preparation method of the above-mentioned gel containing silk essence, comprises the following steps：
Step one, weighs each component according to weight portion；
Step 2, by ESCAROL 507 different monooctyl ester, methyl parahydroxybenzoate, glycerol, Propylene Glycol, Fructus Citri Limoniae Acid, Polyethylene Glycol, butanediol and hyaluronate sodium are added in reactor, under conditions of inert gas shielding, are warming up to 50- 60 DEG C, kept for 10-20 minutes, obtain mixture one；
Step 3, remaining ingredient is added in mixture one, is heated to 50-60 DEG C, is stirred 5-10 minutes, is then lowered the temperature To 4 DEG C, stand and keep 3-5h, obtain the gel containing silk essence.
Wherein, in step 2, noble gases are nitrogen or argon, and the process for being warming up to 50-60 DEG C is with 3-5 DEG C/min Speed is warming up to 50-60 DEG C；It is to be cooled to 4 DEG C with 5-6 DEG C/min of speed that 4 DEG C are cooled in step 3.
Embodiment 3
A kind of gel containing silk essence, including following component in parts by weight：7 parts of silk essence, to dimethylamino benzene first 1.8 parts of the different monooctyl ester of acid, 3.3 parts of methyl parahydroxybenzoate, 2.7 parts of glycerol, 0.3 part of shitosan, glyceryl monostearate 0.4 Part, 0.7 part of Propylene Glycol, 0.2 part of citric acid, 1.8 parts of Polyethylene Glycol, 1.5 parts of butanediol, 2.4 parts of hyaluronate sodium, poly dimethyl 0.4 part of siloxanes, 55 parts of deionized water.
Wherein, Polyethylene Glycol is Macrogol 600.
The preparation method of the above-mentioned gel containing silk essence, comprises the following steps：
Step one, weighs each component according to weight portion；
Step 2, by ESCAROL 507 different monooctyl ester, methyl parahydroxybenzoate, glycerol, Propylene Glycol, Fructus Citri Limoniae Acid, Polyethylene Glycol, butanediol and hyaluronate sodium are added in reactor, under conditions of inert gas shielding, are warming up to 50- 60 DEG C, kept for 10-20 minutes, obtain mixture one；
Step 3, remaining ingredient is added in mixture one, is heated to 50-60 DEG C, is stirred 5-10 minutes, is then lowered the temperature To 4 DEG C, stand and keep 3-5h, obtain the gel containing silk essence.
Wherein, in step 2, noble gases are nitrogen or argon, and the process for being warming up to 50-60 DEG C is with 3-5 DEG C/min Speed is warming up to 50-60 DEG C；It is to be cooled to 4 DEG C with 5-6 DEG C/min of speed that 4 DEG C are cooled in step 3.
Embodiment 4
A kind of gel containing silk essence, including following component in parts by weight：10 parts of silk essence, to dimethylamino benzene first 3 parts of the different monooctyl ester of acid, 4 parts of methyl parahydroxybenzoate, 3 parts of glycerol, 0.4 part of shitosan, 0.5 part of glyceryl monostearate, third 1 part of glycol, 0.3 part of citric acid, 3 parts of Polyethylene Glycol, 2 parts of butanediol, 3 parts of hyaluronate sodium, 0.5 part of polydimethylsiloxane, 60 parts of deionized water.
Wherein, Polyethylene Glycol is Macrogol 600.
The preparation method of the above-mentioned gel containing silk essence, comprises the following steps：
Step one, weighs each component according to weight portion；
Step 2, by ESCAROL 507 different monooctyl ester, methyl parahydroxybenzoate, glycerol, Propylene Glycol, Fructus Citri Limoniae Acid, Polyethylene Glycol, butanediol and hyaluronate sodium are added in reactor, under conditions of inert gas shielding, are warming up to 50- 60 DEG C, kept for 10-20 minutes, obtain mixture one；
Step 3, remaining ingredient is added in mixture one, is heated to 50-60 DEG C, is stirred 5-10 minutes, is then lowered the temperature To 4 DEG C, stand and keep 3-5h, obtain the gel containing silk essence.
Wherein, in step 2, noble gases are nitrogen or argon, and the process for being warming up to 50-60 DEG C is with 3-5 DEG C/min Speed is warming up to 50-60 DEG C；It is to be cooled to 4 DEG C with 5-6 DEG C/min of speed that 4 DEG C are cooled in step 3.
After testing, in 32.5MPa to 37.8MPa, elongation at break is 37% for 1 to 4 gained gel of embodiment, tensile strength To 45%.

Claims (6)

1. it is a kind of containing silk essence gel, it is characterised in that including following component in parts by weight：Silk essence 5-10 parts, to two The different monooctyl ester 1-3 parts of methylaminobenzoate, methyl parahydroxybenzoate 2-4 parts, glycerol 2-3 parts, shitosan 0.1-0.4 parts, Glyceryl monostearate 0.3-0.5 parts, Propylene Glycol 0.5-1 part, citric acid 0.1-0.3 parts, Polyethylene Glycol 1-3 parts, butanediol 1-2 Part, hyaluronate sodium 1-3 parts, polydimethylsiloxane 0.3-0.5 parts, deionized water 45-60 parts.
2. it is according to claim 1 containing silk essence gel, it is characterised in that Polyethylene Glycol is Macrogol 600.
3. described in claim 1 containing silk essence gel preparation method, it is characterised in that comprise the following steps：
Step one, weighs each component according to weight portion；
Step 2, by ESCAROL 507 different monooctyl ester, methyl parahydroxybenzoate, glycerol, Propylene Glycol, citric acid, Polyethylene Glycol, butanediol and hyaluronate sodium are added in reactor, under conditions of inert gas shielding, are warming up to 50-60 DEG C, kept for 10-20 minutes, obtain mixture one；
Step 3, remaining ingredient is added in mixture one, is heated to 50-60 DEG C, is stirred 5-10 minutes, is then cooled to 4 DEG C, stand and keep 3-5h, obtain the gel containing silk essence.
4. it is according to claim 3 containing silk essence gel preparation method, it is characterised in that noble gases in step 2 For nitrogen or argon.
5. it is according to claim 3 containing silk essence gel preparation method, it is characterised in that be warming up in step 2 50-60 DEG C of process is to be warming up to 50-60 DEG C with 3-5 DEG C/min of speed.
6. it is according to claim 3 containing silk essence gel preparation method, it is characterised in that 4 are cooled in step 3 DEG C it is to be cooled to 4 DEG C with 5-6 DEG C/min of speed.
CN201611052675.6A 2016-11-25 2016-11-25 A kind of gel containing silk essence and preparation method thereof Pending CN106539701A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201611052675.6A CN106539701A (en) 2016-11-25 2016-11-25 A kind of gel containing silk essence and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201611052675.6A CN106539701A (en) 2016-11-25 2016-11-25 A kind of gel containing silk essence and preparation method thereof

Publications (1)

Publication Number Publication Date
CN106539701A true CN106539701A (en) 2017-03-29

Family

ID=58395073

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201611052675.6A Pending CN106539701A (en) 2016-11-25 2016-11-25 A kind of gel containing silk essence and preparation method thereof

Country Status (1)

Country Link
CN (1) CN106539701A (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102357070A (en) * 2011-11-10 2012-02-22 深圳市金因生物技术有限公司 Hydrolyzed silk protein/ recombinant human Epidermal Growth Factor (rhEGF) compound skin care facial mask and preparation method thereof
CN104622743A (en) * 2015-01-16 2015-05-20 广东雅威生物科技有限公司 Aloe gel with deep mild moisturizing function and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102357070A (en) * 2011-11-10 2012-02-22 深圳市金因生物技术有限公司 Hydrolyzed silk protein/ recombinant human Epidermal Growth Factor (rhEGF) compound skin care facial mask and preparation method thereof
CN104622743A (en) * 2015-01-16 2015-05-20 广东雅威生物科技有限公司 Aloe gel with deep mild moisturizing function and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
佚名: "UTENA 蚕丝蛋白美肌毛孔收敛凝胶80g", 《COSDNA网址HTTP://WWW.COSDNA.COM/CHS/COSMETIC_D58C76679.HTML》 *

Similar Documents

Publication Publication Date Title
CN106511135B (en) A kind of whitening compound essential oil and preparation method thereof
US10117910B2 (en) Composition of natural vitamin C and fish scale collagen peptide and preparation method thereof
CN105125476A (en) Anti-wrinkle essence and preparing method thereof
CN110522038A (en) The healthy food of composite blueberry, Black Box Tracing and Isin glue collagen peptide
CN107519022B (en) Preparation process and application of modified membrane cloth
CN104906015A (en) Cubilose whitening and beautifying mask
CN109260454A (en) A kind of preparation method and application for the composition for promoting skin collagen to generate
CN110772449A (en) Skin rejuvenation freeze-dried powder and preparation method thereof
CN109771311A (en) A kind of whitening and spot eliminating cream and preparation method thereof
CN113080459A (en) Preparation method of hyaluronic acid oral liquid
CN111358704A (en) Deep-repairing anti-aging composition and preparation method and application thereof
CN104381879A (en) Aloe nata de coco soup and preparation method thereof
CN106539701A (en) A kind of gel containing silk essence and preparation method thereof
CN111012733A (en) Premna microphylla lactic acid face application agent
CN107648585A (en) A kind of anti-ageing anti-wrinkle Essence containing white fungus, aurantiamarin and soluble protein
CN111329988A (en) Donkey-hide gelatin peptide buccal tablet rich in free arginine and preparation method thereof
CN110772445A (en) Skin whitening oligopeptide composition and preparation method thereof
CN101253976B (en) Sand sagebrush seed oil beauty treatment anti-aging health care food
CN115137076A (en) Food composition for moisturizing and preparation method thereof
CN115226820A (en) Whitening and sugar resisting drink composition
CN112226324A (en) Sesame, walnut and donkey-hide gelatin drink and preparation method thereof
CN112494384A (en) Composition for removing dark eye circles, eye mask and preparation method of eye mask
CN111802637A (en) Rose flower sauce and preparation method thereof
CN106176483A (en) A kind of Fructus Hippophae cervical region essence
CN107198243A (en) A kind of underflow health products containing composite enzyme

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20170329

RJ01 Rejection of invention patent application after publication