CN106520379A - Extraction method of borneol essential oil - Google Patents
Extraction method of borneol essential oil Download PDFInfo
- Publication number
- CN106520379A CN106520379A CN201611164986.1A CN201611164986A CN106520379A CN 106520379 A CN106520379 A CN 106520379A CN 201611164986 A CN201611164986 A CN 201611164986A CN 106520379 A CN106520379 A CN 106520379A
- Authority
- CN
- China
- Prior art keywords
- borneol
- essential oil
- water
- natural
- extracting method
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B9/00—Essential oils; Perfumes
- C11B9/02—Recovery or refining of essential oils from raw materials
- C11B9/027—Recovery of volatiles by distillation or stripping
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses an extraction method of borneol essential oil. The extraction method comprises the following steps: (1) collecting Cirmamonun Camphora leaves from Hubei, and naturally drying in the shade; (2) manually crushing the dried Cirmamonun Camphora leaves; (3) screening the crushed leaves; (4) putting the screened leaves into a flask, adding boiled distilled water, and distilling in an oil bath while performing ultrasonic oscillation; (5) performing oil-water separation on the collected distillate, wherein the oil is the borneol essential oil, and condensing the water to obtain coarse crystalline natural camphol; and (6) recrystallizing the coarse crystalline natural camphol to obtain refined natural camphol. The extraction method of borneol essential oil can increase the borneol essential oil yield, improve the production efficiency and reduce the energy consumption.
Description
Technical field
The present invention relates to borneol essential oil production field, especially a kind of extracting method of borneol essential oil.
Background technology
Natural borneol original name kapur, also known as d-Bomeol, as rare Chinese medicine medicinal material and food additives, is many dragons
Indispensable good adjuvant in brain product.It is used as the history of medicine more than 1500 in China's natural borneol.Research shows, imperial
Brain is proven to have antiinflammatory action and anti thrombotic action and excellent antioxidation, can be by improving ischemic tissue of brain
Blood oxygen supply, and then improve the energetic supersession in the region, cerebral ischemia is played a protective role, and determines which has more excellent resisting
Oxidation activity.
Borneol essential oil and natural borneol are obtained using direct water distillation mode in laboratory, and recovery rate is relatively low.But existing
Branches and leaves in some industrialized producing technologies while extracting, the problem for existing be in industrialized production overall yield also compared with
It is low.And after leaf picking of the prior art, needing 10 day time to be dried, occupied ground is big, and production efficiency is relatively low.
The content of the invention
In view of this, the invention provides a kind of extracting method of borneol essential oil, can improve the yield of borneol essential oil, improve
Production efficiency, reducing energy consumption.
The technical scheme is that：A kind of extracting method of borneol essential oil, comprises the following steps：
(1) feedstock capture, is chosen Hubei and produces borneol camphortree leaf (produced with winter and be preferred), dried in the shade naturally；
(2) dry borneol camphortree leaf is rubbed broken by coarse crushing by hand, standby；
(3) sieve, broken blade will be rubbed and be placed in screen cloth, obtain the blade for sieving；
(4) blade that will sieve loads in 1L three neck round bottom flask, adds the distilled water that boils and with 112～114 DEG C of oil baths
Pot is heated, and is aided with supersonic oscillations while steam distillation；
(5) distillate to collecting carries out water-oil separating, wherein oil is borneol essential oil, water is obtained after condensation slightly
Crystallization natural borneol；
(6) coarse crystallization natural borneol obtains refined natural borneol through wash-out, after collecting from alcohol-water recrystallization,
Refined natural borneol obtains sterling natural borneol after freezing, being dried.
Preferably, in the step (3), the mesh number of screen cloth is 10～20 mesh, to obtain the borneol camphor tree of 10～20 mesh
Leaf.
Preferably, in the step (4), borneol camphor tree leaf raw material and the material ratio of distilled water are 50g: 600mL.
Preferably, in the step (4), oil bath distillation time is 2h.
Preferably, in the step (4), the supersonic frequency of supersonic oscillations is 45KHz, and ultrasonic time is 10min.
Preferably, in the step (6) alcohol-water be ethanol mix with water by a certain percentage and ethanol and water volume ratio
For 60%.
Compared with prior art, the present invention has the advantages that：The present invention extracts borneol essence from borneol yellow cinnamon leaf
The method of oil, effectively increases the recovery rate of borneol essential oil, optimizes extracting method, simplify experimental procedure, make final borneol
The yield of essential oil and natural borneol is respectively more than 1.1% and more than 2%, it is adaptable to industrialized production, also effectively reduces energy
Consumption, production process non-environmental-pollution, advantage is clearly.
Description of the drawings
Fig. 1 is the flow chart of the present invention.
Specific embodiment
Below in conjunction with the accompanying drawings and specific embodiment, the present invention will be further described.
As shown in figure 1, a kind of extracting method of borneol essential oil, comprises the following steps：
(1) feedstock capture, is chosen 50g Hubei and produces borneol camphortree leaf (produced with winter and be preferred), dried in the shade naturally.
(2) dry borneol camphortree leaf is rubbed broken by coarse crushing by hand, standby.
(3) broken blade will be rubbed to be placed in the screen cloth of 10～20 mesh, obtains the blade that 10～20 mesh sieve.
Under this step, in laboratory condition, it is too small not rub broken camphortree leaf mesh number, cannot be steamed saturating in heating process,
The gap of storeroom is too small, and borneol essential oil and natural borneol are difficult to overflow with vapor；Mesh number is too high may to cause heating process
Middle feed liquid boiling jetting container, has many material slags and increases the complex of production in product, therefore desirable 10～20 mesh
For selected optimum condition.
(4) blade that will sieve loads in 1L three neck round bottom flask, adds the distilled water that boils of 600mL and with 112～114 DEG C
Oil bath pan is heated, and is aided with supersonic oscillations while steam distillation.
In this step, the material ratio hour of borneol camphor tree leaf raw material and distilled water, borneol essential oil and natural borneol extract low
It is because that the gap of storeroom is little, remains in flask with respect to many vapor, borneol essential oil and borneol is difficult to steam with water
Gas overflows and overflows；When material ratio is excessive, borneol essential oil and natural borneol recovery rate are reduced, it may be possible to affected by device,
Material ratio is too big, may have impact on the pressure and temperature in bottle, so as to the spilling of unfavorable vapor, the amount of liquid one in cucurbit
As less than the 2/3 of volume, therefore to choose the material ratio of borneol camphor tree leaf raw material and distilled water be 50g: 600mL, in this condition
The yield highest of lower gained borneol essential oil and coarse crystallization natural borneol.
In this step, with the time increase of distillation, recovery rate is in increase, but distillation time, more than after 2h, recovery rate is not
Understand increase over time and have conspicuousness to rise, because the material being put into is certain, distill to after the regular hour, portion big absolutely
Point product assay out, therefore is that 2h is from the angle of energy saving optimal oil bath distillation extraction time with steam distillation
Preferably.
In this step, add ultrasonication when, the recovery rate of borneol essential oil and natural borneol is significantly improved, this be due to
The cavitation and mechanical oscillation effect of ultrasonic wave causes borneol essential oil and natural borneol in leaf to be more prone to steam
Overflow and overflow.However, ultrasonic time is too short, it is impossible to crush the cellular elements in kapor leaf well；Ultrasonic time
Long, recovery rate will not also rise, and have certain volatile oil on the contrary and produce, affect the purity of borneol essential oil and natural borneol.
Therefore it is that 45KHz is more suitable that ultrasonic time selects 10min, supersonic frequency, can be used as more excellent extraction conditions.
(5) distillate to collecting carries out water-oil separating, wherein oil is borneol essential oil, water is obtained after condensation slightly
Crystallization natural borneol.
(6) coarse crystallization natural borneol obtains refined natural borneol through wash-out, after collecting from alcohol-water recrystallization,
Refined natural borneol obtains sterling natural borneol after freezing, being dried.
In this step, alcoholic solvent is dissolved in and water-fast chemical property using natural borneol, can select methyl alcohol and ethanol
Two kinds of reagents, methyl alcohol are that have certain toxicity, in order to not affect the property of natural borneol, from ethyl alcohol recrystallization natural borneol,
For the optimal purification condition of natural borneol, alcohol-water is that ethanol is mixed by a certain percentage with water and ethanol is with the volume ratio of water
60%.
Through borneol essential oil obtained in above-mentioned six steps, its recovery rate is significantly improved, and also optimizes extracting method, is simplified
Experimental procedure, makes the yield of final borneol essential oil and natural borneol respectively more than 1.1% and more than 2%, it is adaptable to industry
Metaplasia is produced, and also effectively reduces energy consumption, production process non-environmental-pollution, and advantage is clearly.
The above embodiments are only the preferred embodiments of the present invention, it is impossible to the interest field of the present invention is limited with this, because
This, the modification made according to scope of the present invention patent, equivalent variations, improvement etc. still belong to the scope covered by the present invention.
Claims (6)
1. a kind of extracting method of borneol essential oil, it is characterised in that comprise the following steps：
(1) feedstock capture, is chosen Hubei and produces borneol camphortree leaf (produced with winter and be preferred), dried in the shade naturally；
(2) dry borneol camphortree leaf is rubbed broken by coarse crushing by hand, standby；
(3) sieve, broken blade will be rubbed and be placed in screen cloth, obtain the blade for sieving；
(4) blade that will sieve loads in 1L three neck round bottom flask, adds the distilled water for boiling and is entered with 112～114 DEG C of oil bath pans
Row heating, is aided with supersonic oscillations while steam distillation；
(5) distillate to collecting carries out water-oil separating, wherein oil is borneol essential oil, water obtains coarse crystallization after condensation
Natural borneol；
(6) coarse crystallization natural borneol from alcohol-water recrystallization, obtains refined natural borneol, refines through wash-out, after collecting
Natural borneol obtains sterling natural borneol after freezing, being dried.
2. a kind of extracting method of borneol essential oil according to claim 1, it is characterised in that screen cloth in the step (3)
Mesh number be 10～20 mesh, to obtain the borneol camphortree leaf of 10～20 mesh.
3. a kind of extracting method of borneol essential oil according to claim 1, it is characterised in that borneol in the step (4)
Camphor tree leaf raw material is 50g: 600mL with the material ratio of distilled water.
4. a kind of extracting method of borneol essential oil according to claim 1, it is characterised in that oil bath in the step (4)
Distillation time is 2h.
5. a kind of extracting method of borneol essential oil according to claim 1, it is characterised in that ultrasound in the step (4)
The supersonic frequency of ripple vibration is 45KHz, and ultrasonic time is 10min.
6. the extracting method of a kind of borneol essential oil according to claim 1, it is characterised in that ethanol in the step (6)-
Water is that ethanol is mixed by a certain percentage with water and ethanol and the volume ratio of water are 60%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611164986.1A CN106520379A (en) | 2016-12-16 | 2016-12-16 | Extraction method of borneol essential oil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611164986.1A CN106520379A (en) | 2016-12-16 | 2016-12-16 | Extraction method of borneol essential oil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106520379A true CN106520379A (en) | 2017-03-22 |
Family
ID=58340852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611164986.1A Pending CN106520379A (en) | 2016-12-16 | 2016-12-16 | Extraction method of borneol essential oil |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106520379A (en) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109111346A (en) * | 2017-06-26 | 2019-01-01 | 欧晓英 | A kind of preparation method of not camphorated high-quality natural borneol (d-Bomeol) |
| CN109913318A (en) * | 2019-04-10 | 2019-06-21 | 范加家 | A kind of supercritical extraction method of borneol essential oil |
| CN109971545A (en) * | 2019-04-10 | 2019-07-05 | 范加家 | The high yield processing method of borneol essential oil |
| CN109971546A (en) * | 2019-04-10 | 2019-07-05 | 范加家 | A kind of high-voltage pulse extracting method of borneol essential oil |
| CN109988673A (en) * | 2019-04-10 | 2019-07-09 | 范加家 | A method of improving borneol essential oil yield |
| CN110003981A (en) * | 2019-04-10 | 2019-07-12 | 范加家 | A kind of organic extraction methods of borneol essential oil |
| CN110003984A (en) * | 2019-04-10 | 2019-07-12 | 范加家 | A kind of compound borneol method of extraction of essential oil of steaming extraction |
| CN110003982A (en) * | 2019-04-10 | 2019-07-12 | 范加家 | A kind of combined type borneol method of extraction of essential oil |
| CN110003983A (en) * | 2019-04-10 | 2019-07-12 | 范加家 | A kind of processing method improving borneol essential oil yield |
| CN112730673A (en) * | 2020-12-23 | 2021-04-30 | 广东省林业科学研究院 | Method for extracting organic compounds from plant tissues containing borneol |
| CN114989890A (en) * | 2022-05-25 | 2022-09-02 | 湖南诺泽生物科技有限公司 | Cumin essential oil and preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103601619A (en) * | 2013-11-01 | 2014-02-26 | 宜昌万森生态科技发展有限公司 | Extraction method and extraction equipment of natural borneol |
| CN105753648A (en) * | 2016-03-03 | 2016-07-13 | 陈爱华 | Method for extracting borneol from camphorwood branches and leaves |
| CN105949035A (en) * | 2016-05-09 | 2016-09-21 | 南京明宽信息咨询中心 | Method for extraction of borneol from camphorwood branches and leaves and application |
-
2016
- 2016-12-16 CN CN201611164986.1A patent/CN106520379A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103601619A (en) * | 2013-11-01 | 2014-02-26 | 宜昌万森生态科技发展有限公司 | Extraction method and extraction equipment of natural borneol |
| CN105753648A (en) * | 2016-03-03 | 2016-07-13 | 陈爱华 | Method for extracting borneol from camphorwood branches and leaves |
| CN105949035A (en) * | 2016-05-09 | 2016-09-21 | 南京明宽信息咨询中心 | Method for extraction of borneol from camphorwood branches and leaves and application |
Non-Patent Citations (1)
| Title |
|---|
| 税丕先等: "《现代中药材商品学》", 30 November 2010, 中山大学出版社 * |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109111346A (en) * | 2017-06-26 | 2019-01-01 | 欧晓英 | A kind of preparation method of not camphorated high-quality natural borneol (d-Bomeol) |
| CN109913318A (en) * | 2019-04-10 | 2019-06-21 | 范加家 | A kind of supercritical extraction method of borneol essential oil |
| CN109971545A (en) * | 2019-04-10 | 2019-07-05 | 范加家 | The high yield processing method of borneol essential oil |
| CN109971546A (en) * | 2019-04-10 | 2019-07-05 | 范加家 | A kind of high-voltage pulse extracting method of borneol essential oil |
| CN109988673A (en) * | 2019-04-10 | 2019-07-09 | 范加家 | A method of improving borneol essential oil yield |
| CN110003981A (en) * | 2019-04-10 | 2019-07-12 | 范加家 | A kind of organic extraction methods of borneol essential oil |
| CN110003984A (en) * | 2019-04-10 | 2019-07-12 | 范加家 | A kind of compound borneol method of extraction of essential oil of steaming extraction |
| CN110003982A (en) * | 2019-04-10 | 2019-07-12 | 范加家 | A kind of combined type borneol method of extraction of essential oil |
| CN110003983A (en) * | 2019-04-10 | 2019-07-12 | 范加家 | A kind of processing method improving borneol essential oil yield |
| CN112730673A (en) * | 2020-12-23 | 2021-04-30 | 广东省林业科学研究院 | Method for extracting organic compounds from plant tissues containing borneol |
| CN114989890A (en) * | 2022-05-25 | 2022-09-02 | 湖南诺泽生物科技有限公司 | Cumin essential oil and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106520379A (en) | Extraction method of borneol essential oil | |
| CN101928639A (en) | Natural tea essence prepared by using tea and preparation method thereof | |
| CN104342337B (en) | A kind of production technique of Sunset Abelmoschus Root functional health wine | |
| CN1733785A (en) | Method for extracting chimonin | |
| CN113862083A (en) | Method for improving oil yield and quality of rosa damascena essential oil | |
| CN101422493A (en) | Preparation method and use of ginkgo-leaf extract | |
| CN102453601B (en) | Extraction method of Cinnamomum camphora seed oil by ultrasound-assisted compound enzyme | |
| CN104694248B (en) | A kind of extracting method of litsea citrate oil | |
| CN105237339B (en) | The method that n-octacosanol is extracted by raw material of sugar refinery mix indicator technique | |
| CN101775333A (en) | Supercritical CO2 method for extracting barbadosnut seed oil and product thereof | |
| CN104450152A (en) | Compound technology for extracting tea seed oil employing aqueous enzymatic method | |
| CN104610394A (en) | Method for extracting phlorizin with different purity from twigs and green leaves of Malus hupehensis | |
| CN105878323A (en) | Method using ultrasonically-assisted supercritical extraction rectification to purify cynarin in globe artichoke | |
| CN103304378A (en) | Method for processing natural borneol and sublimation tank for producing natural borneol | |
| CN107098797A (en) | A kind of extracting method of chavicol methyl ether | |
| CN102516011A (en) | Extraction method for lycopene | |
| CN101092586A (en) | Method for preparing sarcodactylis oil | |
| CN104844721A (en) | Extraction and separation method of Agrocybe aegirit polysaccharides | |
| CN105378092A (en) | Process for making furfural | |
| CN102732375A (en) | Extraction method for lacquer seed oil | |
| CN107574017A (en) | A kind of lindera glauca essential oil extracting device | |
| CN109293728A (en) | A kind of green low cost preparation method of high-purity tea saponin | |
| CN104151377A (en) | Technology and method for extraction of teasaponin from Camellia oleifera Abel seed meal | |
| JP2011105646A (en) | Method for producing hesperidin | |
| CN107759578A (en) | A kind of extracting method of silymarin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170322 |
|
| RJ01 | Rejection of invention patent application after publication |