CN106474633A - Neutron capture treatment system - Google Patents
Neutron capture treatment system Download PDFInfo
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- CN106474633A CN106474633A CN201510770609.1A CN201510770609A CN106474633A CN 106474633 A CN106474633 A CN 106474633A CN 201510770609 A CN201510770609 A CN 201510770609A CN 106474633 A CN106474633 A CN 106474633A
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- neutron
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- generating unit
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- door lock
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/103—Treatment planning systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1042—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy with spatial modulation of the radiation beam within the treatment head
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
- A61N2005/109—Neutrons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1092—Details
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- General Health & Medical Sciences (AREA)
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- Radiation-Therapy Devices (AREA)
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Abstract
The application provides a kind of neutron capture treatment system, including beam-shaping body, which includes beam entrance, neutron generating unit in beam-shaping body, it is adjacent to the slow body of neutron generating unit, it is enclosed in slowly external reflector and beam outlet, there is nuclear reaction to produce neutron with from the incident proton beam of beam entrance in neutron generating unit, slow body will be slow for the neutron produced from neutron generating unit, the neutron that reflector will deviate from is back to the slow body to improve epithermal neutron intensity of beam, beam-shaping body include at least one can to away from or the movable part that moves near neutron generating unit direction, the movable part has primary importance and the second place, the movable part is moved between primary importance and the second place, when movable part is located at primary importance, neutron generating unit can be replaced；When movable part is located at the second place, neutron generating unit can not be replaced.It is convenient that the application neutron generating unit is changed, simple structure, use flexibly.
Description
Technical field
The present invention relates to a kind of neutron capture treatment system, more particularly to a kind of neutron capture treatment that can change neutron generating unit
System.
Background technology
With the development of atomics, the such as radiation cure such as cobalt 60, linear accelerator, electron beam has become cancer and has controlled
One of Main Means for the treatment of.But conventional photonic or electronic therapy are limited by radioactive ray physical condition itself, tumour is being killed
While cell, also substantial amounts of normal structure in beam approach can be damaged；Sensitive to radioactive ray additionally, due to tumour cell
The difference of degree, traditional radiation therapy for relatively have radiation resistance malignant tumour (such as：Multirow glioblastoma
(glioblastoma multiforme), melanocytoma (melanoma)) treatment effect often not good.
In order to reduce the radiation injury of tumour surrounding normal tissue, the target therapy concept in chemotherapy (chemotherapy) is just
It is applied in radiation cure；And the tumour cell of radiation resistance is directed to, also actively development has high Relative biological effect at present
The radiation source of (relative biological effectiveness, RBE) is answered, such as proton therapeutic, heavy particle therapy, neutron capture is controlled
Treat etc..Wherein, neutron capture treatment is that such as boron neutron capture treatment, by boracic medicine swollen with reference to above two concept
The specificity of oncocyte is gathered, and coordinates accurately neutron beam regulation and control, provides and select than the more preferable treatment of cancer of conventional radiation.
In the treatment of accelerator boron neutron capture, the neutron generating unit needs of neutron beam are produced for there is nuclear reaction with proton beam
Stand the irradiation of accelerating proton and activation can produce a certain degree of damage, and product of neutron beam of the neutron generating unit to producing
Matter has very important impact, in order to reduce impact of the neutron generating unit to neutron beam quality, must periodic replacement neutron generating unit.
However, accelerator boron neutron capture of the prior art treats slow body is mostly cylinder, neutron generating unit is generally arranged
In the slow body of certain depth, when neutron generating unit be damaged need change when, it is necessary to take more multiple steps to be dismantled
Get off, this may result in more changing jobs for neutron generating unit and is difficult to carry out.
Therefore, it is necessary in fact to provide a kind of new technical scheme to solve the above problems.
Content of the invention
In order to solve the above problems, one aspect of the present invention provides a kind of neutron capture treatment system, including beam-shaping body,
The beam-shaping body includes beam entrance, the neutron generating unit in beam-shaping body, is adjacent to the slow of neutron generating unit
Body, be enclosed in neutron generating unit and slowly external reflector and beam outlet, the neutron generating unit with from the beam entrance
There is nuclear reaction to produce neutron in incident proton beam, the slow body is slow by the neutron produced from the neutron generating unit, institute
Neutron that reflector will deviate from is stated back to the slow body to improve epithermal neutron intensity of beam, the beam-shaping body include to
Few one can to away from or the movable part that moves near neutron generating unit direction, the movable part is in primary importance and second
Move between putting, when movable part is located at primary importance, neutron generating unit can be replaced；When movable part is located at the second place,
When movable part is located at the second place, neutron generating unit can not be replaced.
Further, for the ease of the replacing of neutron generating unit, as a kind of preferably, the movable part be partial reflector or
Person's partial reflector is combined with the slow body in part.
Further, for the ease of the taking-up of neutron generating unit, the movable part has symmetrical plane, and the movable part is along this pair
Claim plane symmetry, the neutron generating unit has an axis, the symmetrical plane of the movable part through the axis of the neutron generating unit,
The reflector has first straight line height, and the movable part has second straight line height, and it is straight that the neutron generating unit has the 3rd
Line height, the second straight line are highly more than the 3rd straight line height less than or equal to first straight line height.
Further, when the movable part second straight line highly be equal to reflector first straight line height when, if movable part and
Faying face between reflector is the connection between plane and plane, and the radiation that underway sub- capture is produced during treating is just
Can be revealed by the faying face, as one kind preferably, the reflector has first connecting portion, and the first connecting portion has
First joint face and the first faying face, the movable part have second connecting portion, the second connecting portion have the second joint face and
Second faying face, when the second straight line of movable part is highly more than the 3rd of neutron generating unit less than the first straight line height of reflector
During straight line height, the first joint face of the reflector is overlapped with the first faying face, the second joint face of the movable part and second
Faying face overlaps, and the second faying face of the movable part is connected with the first faying face of reflector and adds neutron generating unit axle with described
Any one plane that line is located overlaps.
Further, the reflector has first connecting portion, and the first connecting portion has the first joint face and the first faying face,
The movable part has second connecting portion, and the second connecting portion has the second joint face and the second faying face, when the movable part
Second straight line highly be equal to reflector first straight line height when, first joint face and the first faying face connection but be located at not
Isoplanar, second joint face are connected with the second faying face but are located at Different Plane, first joint face and the second joint face
Connection, the first faying face are connected with the second faying face.
Further, the neutron capture treatment system also includes drive component, and the drive component includes the door for carrying movable part
Lock and allow door lock to away from or the guide rail that moves near neutron generating unit direction, the door lock along guide rail to away from or close
The direction motion of beam-shaping body, when door lock to move away from beam-shaping body direction when, the movable part is to producing away from neutron
The direction motion in portion；When door lock is moved to the direction of close beam-shaping body, the movable part is near the side of neutron generating unit
To motion.
Further, the guide rail is external located at beam-shaping, and the drive component also includes bracing frame, and the one of support frame as described above
End supports the door lock other end move in guide rail, the door lock with bracing frame move along the rail and to away from or close beam whole
The direction motion of body.
Further, the neutron capture treatment system also includes drive component, and the drive component includes door lock and supports door lock
And the tumbler that door lock rotates is allowed, the door lock supports movable part, when door lock is rotated up, the movable part around tumbler
Move to the direction near neutron generating unit；When door lock is rotated down around tumbler, the movable part is to away from neutron generating unit
Direction motion.
Further, described also include drive component for neutron capture treatment system, the drive component include first connecting rod,
Second connecting rod and the third connecting rod of first, second connecting rod of connection, the first connecting rod are fixed on beam-shaping in vitro, and described second
One end of connecting rod is fixed on the movable part other end and is connected to first connecting rod, and the first connecting rod drives third connecting rod motion, and the 3rd connects
Bar drive second connecting rod motion so that movable part to away from or move near the direction of neutron generating unit.
Further, when the second straight line of the movable part is highly more than neutron product less than the first straight line height of the reflector
The 3rd straight line height in life portion, the reflection is provided with guide rail in vivo, and the movable part is installed in beam-shaping body and can be along leading
Rail so as to away from or move near the direction of neutron generating unit.
Compared with prior art, the application has the advantages that：The application by setting can to away from or near neutron
The movable part of generating unit direction motion, is easy to the replacing of neutron generating unit, simple structure, use flexibly.
Description of the drawings
Fig. 1 is the schematic diagram of the application neutron capture treatment system；
Fig. 2 a the application movable part is located at the schematic diagram of the second place；
Fig. 2 b is the schematic diagram that the application movable part is located at primary importance；
Fig. 3 a be the second faying face of herein described movable part be connected with the first faying face of reflector and with the neutron generating unit
The schematic diagram that axis place plane overlaps；
Fig. 3 b is sectional view of the application movable part along symmetrical plane A；
Fig. 4 a is the schematic diagram that the first joint face of reflector and the inclined angle of the first faying face are arranged；
Fig. 4 b is the groove surface schematic diagram mutually chimeric with the raised face of reflector of movable part；
Fig. 5 a is that piecemeal activity part is embedded the schematic diagram in door lock；
Fig. 5 b is the schematic diagram that drive component has bracing frame；
Fig. 6 is the schematic diagram of the embodiment of the present application two；
Fig. 7 is the schematic diagram of the embodiment of the present application three；
Fig. 8 is the schematic diagram of the embodiment of the present application four.
Specific embodiment
Neutron capture is treated the application as a kind of means of effective treating cancer in recent years and is gradually increased, and is wherein caught with boron neutron
Obtain that treatment is most commonly seen, the neutron for supplying the treatment of boron neutron capture can be supplied by nuclear reactor or accelerator.The enforcement of the application
By taking the treatment of accelerator boron neutron capture as an example, the basic module of accelerator boron neutron capture treatment is generally included for band electrochondria example
Accelerator, neutron generating unit and hot removal system and beam-shaping body that sub (such as proton, deuteron etc.) is accelerated, wherein
Accelerate charged particle and neutron is produced with the effect of metal neutron generating unit, according to required neutron yield rate and energy, available acceleration
Charged particle energy selects suitable nuclear reaction with the characteristic such as size of current, materialization of metal neutron generating unit, often comes into question
Nuclear reaction have7Li(p,n)7Be and9Be(p,n)9B, both reactions are all the endothermic reaction.The energy threshold of two kinds of nuclear reactions is divided
Not Wei 1.881MeV and 2.055MeV, due to boron neutron capture treatment preferable neutron source be keV energy grade epithermal neutron,
If being only slightly taller than the proton bombardment lithium metal neutron generating unit of threshold values in theory using energy, the neutron of relative low energy can be produced, no
Must too many slow process just can be used for clinic, but two kinds of neutron generating units of lithium metal (Li) and beryllium metal (Be) and threshold values
The proton-effect section of energy is not high, is to produce sufficiently large neutron flux, generally selects the proton of higher-energy to carry out initiated core anti-
Should.
Preferably neutron generating unit should possess high neutron yield rate, the neutron energy distribution of generation is close to epithermal neutron energy area, no too many
Wear by force radiation produce, cheaply easily operated and high temperature resistant etc. characteristic of safety, but actually and cannot find and meet required core
Reaction.In boron neutron capture therapeutic process, neutron generating unit will necessarily be subject to due to impacting by accelerating proton, radiating
Damage, and neutron generating unit has very big impact to the quality of the neutron beam that beam-shaping body is produced, so regular or root
Neutron generating unit is just changed according to the damage situations of neutron generating unit and seemed necessary, be described below during one kind can change
The neutron capture treatment system of sub- generating unit.
Fig. 1 is the schematic diagram of the application neutron capture treatment system 100.The neutron capture treatment system 100 includes that beam is whole
Body 10 and drive component 20.
The beam-shaping body 10 includes beam entrance 11, neutron generating unit 12, is adjacent to the slow body of neutron generating unit 12
13rd, the reflector 14 and beam outlet 15 outside being enclosed in neutron generating unit 12 and slow body 13.The neutron generating unit 12 with
There is nuclear reaction to produce neutron from the proton beam of 11 incidence of beam entrance, the slow body 13 pairs is produced from the neutron
Portion 12 produce neutron carry out slowly, the neutron that the reflector 14 will deviate from back to the slow body 13 with improve superthermal in
Sub-beam intensity.
The reflector 14 include at least one can to away from or the movable part 16 that moves near 12 direction of neutron generating unit.
The movable part 16 with primary importance L1 and second place L2 (in conjunction with Fig. 2 a and Fig. 2 b), the movable part 16 this
Move between one position L1 and second place L2, when movable part 16 is located at primary importance L1, neutron generating unit 12 can
It is replaced；When movable part 16 is located at second place L2, neutron generating unit 12 can not be replaced.Specifically, when described
Movable part 16 to the direction away from neutron generating unit 12 move to primary importance L1 when, neutron generating unit 12 is from beam-shaping body
10 expose, and take out neutron generating unit 12 and neutron generating unit 12 is changed；When the neutron generating unit 12 that more finishes changing is installed
After beam-shaping body 10 is interior, the movable part 16 is (living to second place L2 is moved near the direction of neutron generating unit 12
Moving part 16 is coated on the periphery of neutron generating unit 12, and neutron generating unit 12 can not be replaced), treat in follow-up neutron capture
During the movable part 16 and reflector 14 lead back to jointly the neutron of deviation.
The movable part 16 can be partial reflector or partial reflector and the combining of the slow body in part.Movable part 16 is portion
The situation of reflector is divided to refer to that neutron generating unit 12 is arranged on the front of slow body 13 and is enveloped by reflector 14, slow body 13
The rear of neutron generating unit 12 being abutted against, as long as now partial reflector is set to mobilizable structure (i.e. movable part), being led to
Cross movable part away from changing neutron generating unit.Movable part 16 is that the situation of the slow body combination of partial reflector and part is referred to,
A part for neutron generating unit 12 is located at the front of slow body 13 and is coated by reflector 14, and a part is embedded in slow body 13
Coated by slow body 13, now in order to neutron generating unit 12 is changed, the part being coated on outside neutron generating unit 12 is reflected
The slow body of body and part is set to mobilizable structure (i.e. movable part), so as to realize the replacing of neutron generating unit 12.
In conjunction with Fig. 3 a and Fig. 3 b, for the ease of the replacing of neutron generating unit 12, as one kind preferably, the movable part 16
For symmetrical member, the symmetrical member has symmetrical plane A, and movable part 16 is symmetrical along symmetrical plane A, the symmetrical plane A warp
The axis I of the neutron generating unit 12 is crossed, with first straight line height H1, the movable part 16 has the to the reflector 14
Two straight line height H2, the neutron generating unit 12 have the 3rd straight line height H3, the second straight line height of the movable part 16
H2 is more than the 3rd straight line height of the neutron generating unit 12 less than or equal to the first straight line height H1 of reflector 14
H3.
In conjunction with Fig. 4 a and Fig. 4 b, the reflector 14 also has first connecting portion 140, and the movable part 16 is with the second connection
Portion 160.The first connecting portion 140 has the first joint face 141 and the first faying face 142 being connected with the first joint face 141,
The second connecting portion 160 has the second joint face 161 and the second faying face 162 being connected with the second joint face 161.
When the second straight line height H2 of the movable part 16 is more than the neutron less than the first straight line height H1 of reflector 14
During the 3rd straight line height H3 of generating unit 12, the first joint face 141 of the reflector 14 is overlapped with the first faying face 142,
Second joint face 161 of the movable part 16 is overlapped with the second faying face 162, the second faying face 162 of the movable part 16
It is connected with the first faying face 142 of reflector 14 and overlaps (such as with any one plane that the axis of the neutron generating unit 12 is located
Fig. 3 a).Now the movable part 16 be reflector 14 a part, in this case, when the movable part 16 to
When moving to primary importance L1 away from the direction of neutron generating unit 12, movable part 16 forms breach on the reflector 14,
The neutron generating unit 12 is exposed from the breach, neutron generating unit 12 is changed in the indentation, there；When the movable part 16
To when moving to second place L2 near the direction of neutron generating unit 12, the movable part 16 is enclosed in the neutron generating unit
12 periphery, in follow-up neutron capture therapeutic process, movable part 16 and reflector 14 lead back to the neutron of deviation jointly.
When the second straight line height H2 of the movable part 16 is equal to the first straight line height H1 of reflector 14, the movable part
16 half for being the reflector 14 for being enclosed in 12 periphery of neutron generating unit.In order to reduce in follow-up neutron capture therapeutic process
The particle leaked from the junction of movable part 16 and reflector 14 or radiation, as one kind preferably, the reflector 14
First joint face 141 and the first faying face 142 are located at Different Plane, the second joint face 161 of the movable part 16 and the second knot
Conjunction face 162 is located at Different Plane, and first joint face 141 fitted with the second joint face 161, the first faying face 142 and the
Two faying faces 162 are fitted.First connecting portion 140 specific as follows can be arranged (in conjunction with Fig. 4 a) with second connecting portion 160, and second
Joint face 161 and 162 inclined angle of the second faying face are arranged, and first faying face 142 is inclined with the first joint face 141
Angle arrange, both of the aforesaid inclination angle and be 180 degree.When movable part 16 is enclosed in the periphery when institute of the neutron generating unit 12
State the second faying face 162 to fit with the first faying face 142, the second joint face 161 is fitted with the first joint face 141.First connects
Socket part 140 also can be arranged (in conjunction with Fig. 4 b) as follows with second connecting portion 160, and second faying face 162 is to connect from second
The recessed groove surface in face 161, first faying face 142 are the raised face projected from the first joint face 141, when movable part 16
Be enclosed in the neutron generating unit 12 periphery when groove surface and raised face be mutually fitted together to.
The structure of drive component 20 is introduced in detail below, separately, because having carried out Jie in detail above to the structure of movable part 16
Continue, be hereafter just not repeated description, in actual application, can according to real needs by the structure of above-mentioned movable part 16 with
Drive component 20 hereinafter described is combined, although and it is all to enter so that reflector has two movable parts as an example in Examples below
Row explanation, but the replacing of neutron generating unit 12 can be easy to if a movable part 16 is set in actual application,
One movable part is so set.
It is also embodiments herein one shown in Fig. 2 a and Fig. 2 b, the embodiment is that have two with reflector 14 to be located at neutron
It is introduced as a example by the movable part 16 (i.e. the first movable part 163 and the second movable part 164) of 12 both sides of generating unit and interconnection.
The drive component 20 includes the guide rail 21 outside beam-shaping body 10 and supports the door lock 22 of movable part 16, the door lock
22 move in guide rail 21 with drive movable part 16 to away from or move near the direction of neutron generating unit 12.Movable part 16
Including the first movable part 163 and the second movable part 164, the door lock 22 includes 221 He of the first door lock that moves along guide rail 21
Second door lock 222, first door lock 221 support the first movable part 163, and second door lock 222 supports the second movable part
164.First door lock 221 and the second door lock 222 are moved in guide rail 21 and drive first movable part 163 and respectively
Two movable parts 164 to away from or move near the direction of neutron generating unit 12.When the first door lock 221 and 222 points of the second door lock
Not to the direction away from beam-shaping body 10 move to primary importance L1 when, first movable part 163 and the second movable part 164
Also move to the direction away from neutron generating unit 12 respectively, now neutron generating unit 12 is exposed from beam-shaping body 10, centering
Sub- generating unit 12 is changed；When the first door lock 221 and the second door lock 222 are respectively near the direction of neutron generating unit 12 fortune
When moving second place L2, first movable part 163 and the second movable part 164 are also near the direction of neutron generating unit 12
Motion is coated on 12 periphery of neutron generating unit until the first movable part 163 and the second movable part 164, controls in follow-up neutron capture
During treatment, first movable part 163 and the second movable part 164 are used for leading back to the neutron of deviation.
For the ease of structure design, as one kind preferably, the structure phase of first movable part 163 and the second movable part 164
With first door lock 221 is identical with the structure of the second door lock 222, infra for being easy to introduce, all to be referred to as movable part
16 and door lock 22 be introduced.
The structure of the door lock 22 can have many kinds, in the present embodiment, second straight line height H2 of the movable part 16 etc.
When the first straight line height H1 of reflector 14, door lock 22 is coated on the periphery of movable part 16, it can be understood as movable part 16
It is entrenched in door lock 22, motion of the door lock 22 in guide rail 21 is equivalent to the open and close movement of door lock 22, the movable part
16 with door lock 22 folding away from or near neutron generating unit 12.As one kind preferably, the door lock 22 is by concrete system
Become.Certainly, for save space or cost, it is also possible to which the even less part of the half of movable part 16 is embedded in door lock
In 22 (in conjunction with Fig. 5 a), if door lock 22 be designed to support the movable part 16, and movable part 16 can be driven to remote
From or direction motion near neutron generating unit 12.When the second straight line height H2 of movable part 16 is less than reflector 14
First straight line height when bracing frame 23 (in conjunction with Fig. 5 b) can also be set between door lock 22 and guide rail 21.Support frame as described above
23 one end is fixed with door lock 22, the other end in guide rail 21 to away from or move near the direction of beam-shaping body 10.
The movable part 16 with door lock 22 motion along guide rail 21 to away from or move near the direction of neutron generating unit 12.Also
It is to say, motion of the door lock 22 by bracing frame 23 in guide rail 21 drives door lock 22 to move to avoid the need for door lock 22
Being arranged to sufficiently large size makes which directly move in guide rail 21, so as to reduce the size of door lock 22.
Fig. 6 show the schematic diagram of the embodiment of the present application two.The drive component 20 includes tumbler 24 (as shaft member) and consolidates
The door lock 22 ' being held on tumbler 24.The tumbler 24 is located at the underface of beam-shaping body 10 and the tumbler 24
Axis and the neutron generating unit 12 diameter parallel.The door lock 22 ' is rotated upwardly and downwardly around tumbler 24, when the door lock
22 ' when moving downward, and the door lock 22 ' drives movable part 16 to move to the direction away from neutron generating unit 12, the neutron
Generating unit 12 is exposed, and changes neutron generating unit 12；When door lock 22 ' is rotated up, movable part 16 is driven near neutron product
The direction in life portion 12 rotates, and the movable part 16 is enclosed in 12 periphery of neutron generating unit, in follow-up neutron capture therapeutic process
For leading back to the neutron of deviation.
Fig. 7 implements three schematic diagram for the application.Drive component 20 described in the present embodiment includes to be fixed on beam-shaping body 10
The of outer first connecting rod 25, the second connecting rod 26 for being connected to movable part 16 and connection first connecting rod 25 and second connecting rod 26
Three connecting rods 27, the motion of the third connecting rod 27 drive second connecting rod 26 to move, and the movable part 16 is with the fortune of second connecting rod 26
Trend away from or direction motion near neutron generating unit 12.
Fig. 8 is the schematic diagram of the embodiment of the present application four.When the second straight line height H2 of movable part 16 is less than the reflector 14
First straight line height H1 when (especially when movable part 16 second straight line height H2 less than neutron generating unit 12 the 3rd straight line
During height H3), guide rail 28 can be set in reflector 14, and the outside wall surface in movable part 16 arranges handle 165, passes through
Drawing handle 165 drive movable part 16 along guide rail 28 to away from or move near the direction of neutron generating unit 12.Certainly,
Drive component in above-described embodiment one to embodiment three can be applied to substitute handle in the present embodiment, just not detailed herein
Introduce.
The neutron capture treatment system that the application is disclosed is not limited to the content described in above example and the knot represented by accompanying drawing
Structure.Apparently change that material, shape and position on the basis of the application to wherein component is made, substitute or repair
Change, all this application claims within the scope of.
Claims (10)
1. a kind of neutron capture treatment system, including beam-shaping body, it is characterised in that：The beam-shaping body include beam entrance,
Neutron generating unit in beam-shaping body, it is adjacent to the slow body of neutron generating unit, is enclosed in neutron generating unit and slow
External reflector and beam outlet, the neutron generating unit with from the incident proton beam of the beam entrance occur nuclear reaction with
Neutron is produced, the slow body is slow by the neutron produced from the neutron generating unit, and the neutron that the reflector will deviate from is led
The slow body is back to improve epithermal neutron intensity of beam, the beam-shaping body include at least one can to away from or
Near the movable part of neutron generating unit direction motion, the movable part has primary importance and the second place, and the movable part exists
Move between primary importance and the second place, when movable part is located at primary importance, neutron generating unit can be replaced；When
When movable part is located at the second place, neutron generating unit can not be replaced.
2. neutron capture treatment system according to claim 1, it is characterised in that：The movable part is partial reflector or portion
Slow the combining of body in point reflector and part.
3. neutron capture treatment system according to claim 1, it is characterised in that：The movable part has symmetrical plane, described
Movable part is symmetrical along the symmetrical plane, and the neutron generating unit has axis, and the symmetrical plane of the movable part is in described
The axis of sub- generating unit, the reflector have first straight line height, the movable part have second straight line height, described in
Sub- generating unit has the 3rd straight line height, and it is straight that the second straight line is highly more than the 3rd less than or equal to first straight line height
Line height.
4. neutron capture treatment system according to claim 2, it is characterised in that：The reflector has first connecting portion, institute
State first connecting portion and there is the first joint face and the first faying face, the movable part has second connecting portion, second connection
Portion has the second joint face and the second faying face, when movable part second straight line highly less than reflector first straight line highly and
More than neutron generating unit the 3rd straight line height when, the first joint face of the reflector is overlapped with the first faying face, the work
Second joint face of moving part is overlapped with the second faying face, and the second faying face of the movable part is connected with the first faying face of reflector
Any one plane for connecing and being located with described plus neutron generating unit axis is overlapped.
5. neutron capture treatment system according to claim 2, it is characterised in that：The reflector has first connecting portion, institute
State first connecting portion and there is the first joint face and the first faying face, the movable part has second connecting portion, second connection
Portion has the second joint face and the second faying face, when the second straight line of the movable part is highly equal to the first straight line height of reflector
When spending, first joint face and the first faying face connect but are located at Different Plane, second joint face and the second faying face
Connect but Different Plane is located at, first joint face is connected with the second joint face, and the first faying face is connected with the second faying face.
6. neutron capture treatment system according to claim 1, it is characterised in that：The neutron capture treatment system also includes to drive
Dynamic component, the drive component include the door lock for carrying movable part and allow door lock to away from or near neutron generating unit direction
The guide rail of motion, the door lock along guide rail to away from or move near the direction of beam-shaping body, when door lock is to away from beam
When shaping body direction is moved, the movable part is moved to the direction away from neutron generating unit；When door lock is near beam-shaping body
Direction when moving, the movable part is to moving near the direction of neutron generating unit.
7. neutron capture treatment system according to claim 6, it is characterised in that：The guide rail is external located at beam-shaping, institute
Stating drive component also includes bracing frame, and one end of support frame as described above supports the door lock other end to move in guide rail, the door lock with
Bracing frame move along the rail and to away from or move near the direction of beam-shaping body.
8. neutron capture treatment system according to claim 1, it is characterised in that：The neutron capture treatment system also includes to drive
Dynamic component, the drive component include door lock and support door lock and allow the tumbler of door lock rotation, the door lock support activity
Part, when door lock is rotated up around tumbler, the movable part is moved to the direction near neutron generating unit；When door lock rotates
When moving part is rotated down, the movable part is moved to the direction away from neutron generating unit.
9. neutron capture treatment system according to claim 1, it is characterised in that：Described also wrap for neutron capture treatment system
Drive component is included, the drive component includes the third connecting rod of first connecting rod, second connecting rod and first, second connecting rod of connection,
The first connecting rod is fixed on beam-shaping in vitro, and one end of the second connecting rod is fixed on the movable part other end and is connected to first
Connecting rod, the first connecting rod drive third connecting rod motion, and third connecting rod drives second connecting rod motion so that movable part is to remote
From or near neutron generating unit direction move.
10. neutron capture treatment system according to claim 2, it is characterised in that：When the second straight line of the movable part is high
Degree is more than the 3rd straight line height of neutron generating unit less than the first straight line height of the reflector, and the reflection is provided with vivo
Guide rail, the movable part be installed in beam-shaping body and can along guide rail to away from or transport near the direction of neutron generating unit
Dynamic.
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710545486.0A CN107412962B (en) | 2015-11-12 | 2015-11-12 | Neutron capture treatment system |
| CN201510770609.1A CN106474633B (en) | 2015-11-12 | 2015-11-12 | Neutron capture treatment system |
| CN201710545459.3A CN107412961B (en) | 2015-11-12 | 2015-11-12 | Neutron capture treatment system |
| CN201710544870.9A CN107412960B (en) | 2015-11-12 | 2015-11-12 | Neutron capture treatment system |
| CN201710545372.6A CN107569781B (en) | 2015-11-12 | 2015-11-12 | Neutron capture therapy system |
| RU2019113042A RU2717364C1 (en) | 2015-11-12 | 2016-10-18 | Neutron capturing therapy system |
| EP19187968.3A EP3586922B1 (en) | 2015-11-12 | 2016-10-18 | Neutron capture therapy system |
| EP16863521.7A EP3357536B1 (en) | 2015-11-12 | 2016-10-18 | Neutron capture therapy system |
| JP2018523819A JP6830483B2 (en) | 2015-11-12 | 2016-10-18 | Neutron capture therapy system |
| PCT/CN2016/102332 WO2017080344A1 (en) | 2015-11-12 | 2016-10-18 | Neutron capture therapy system |
| TW105217113U TWM541312U (en) | 2015-11-12 | 2016-11-10 | Neutron capture therapy system |
| US15/967,727 US10898731B2 (en) | 2015-11-12 | 2018-05-01 | Neutron capture therapy system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510770609.1A CN106474633B (en) | 2015-11-12 | 2015-11-12 | Neutron capture treatment system |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710545486.0A Division CN107412962B (en) | 2015-11-12 | 2015-11-12 | Neutron capture treatment system |
| CN201710544870.9A Division CN107412960B (en) | 2015-11-12 | 2015-11-12 | Neutron capture treatment system |
| CN201710545372.6A Division CN107569781B (en) | 2015-11-12 | 2015-11-12 | Neutron capture therapy system |
| CN201710545459.3A Division CN107412961B (en) | 2015-11-12 | 2015-11-12 | Neutron capture treatment system |
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| CN106474633A true CN106474633A (en) | 2017-03-08 |
| CN106474633B CN106474633B (en) | 2017-11-10 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201510770609.1A Active CN106474633B (en) | 2015-11-12 | 2015-11-12 | Neutron capture treatment system |
| CN201710545459.3A Active CN107412961B (en) | 2015-11-12 | 2015-11-12 | Neutron capture treatment system |
| CN201710545486.0A Active CN107412962B (en) | 2015-11-12 | 2015-11-12 | Neutron capture treatment system |
| CN201710544870.9A Active CN107412960B (en) | 2015-11-12 | 2015-11-12 | Neutron capture treatment system |
| CN201710545372.6A Active CN107569781B (en) | 2015-11-12 | 2015-11-12 | Neutron capture therapy system |
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| CN201710545459.3A Active CN107412961B (en) | 2015-11-12 | 2015-11-12 | Neutron capture treatment system |
| CN201710545486.0A Active CN107412962B (en) | 2015-11-12 | 2015-11-12 | Neutron capture treatment system |
| CN201710544870.9A Active CN107412960B (en) | 2015-11-12 | 2015-11-12 | Neutron capture treatment system |
| CN201710545372.6A Active CN107569781B (en) | 2015-11-12 | 2015-11-12 | Neutron capture therapy system |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019114308A1 (en) * | 2017-12-15 | 2019-06-20 | 南京中硼联康医疗科技有限公司 | Neutron capture therapy system |
| CN109925607A (en) * | 2017-12-15 | 2019-06-25 | 南京中硼联康医疗科技有限公司 | Neutron capture treatment system |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109925610B (en) * | 2017-12-15 | 2024-03-22 | 南京中硼联康医疗科技有限公司 | Neutron capture therapy system |
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Also Published As
| Publication number | Publication date |
|---|---|
| CN107412962B (en) | 2019-08-20 |
| CN107412961A (en) | 2017-12-01 |
| CN107412961B (en) | 2019-08-06 |
| CN107412960A (en) | 2017-12-01 |
| CN107412960B (en) | 2019-08-06 |
| CN107412962A (en) | 2017-12-01 |
| CN107569781B (en) | 2019-12-13 |
| CN106474633B (en) | 2017-11-10 |
| CN107569781A (en) | 2018-01-12 |
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