CN106432090A - 一种氘代咪唑酮化合物的晶型及其制备方法和用途 - Google Patents
一种氘代咪唑酮化合物的晶型及其制备方法和用途 Download PDFInfo
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- CN106432090A CN106432090A CN201610609034.XA CN201610609034A CN106432090A CN 106432090 A CN106432090 A CN 106432090A CN 201610609034 A CN201610609034 A CN 201610609034A CN 106432090 A CN106432090 A CN 106432090A
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- crystal formation
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- dimethyl
- thio
- trifluoromethyl
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
Claims (17)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2015107263252 | 2015-10-30 | ||
CN201510726325 | 2015-10-30 |
Publications (2)
Publication Number | Publication Date |
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CN106432090A true CN106432090A (zh) | 2017-02-22 |
CN106432090B CN106432090B (zh) | 2019-08-20 |
Family
ID=58184308
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201610609034.XA Active CN106432090B (zh) | 2015-10-30 | 2016-07-28 | 一种氘代咪唑酮化合物的晶型及其制备方法和用途 |
Country Status (3)
Country | Link |
---|---|
CN (1) | CN106432090B (zh) |
TW (1) | TWI638810B (zh) |
WO (1) | WO2017071375A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019218979A1 (zh) * | 2018-05-14 | 2019-11-21 | 成都海创药业有限公司 | 一种hc-1119制剂及其制备方法和用途 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103159680A (zh) * | 2011-12-14 | 2013-06-19 | 爱美尼迪药物有限公司 | 咪唑二酮类化合物及其用途 |
CN104341352A (zh) * | 2013-08-09 | 2015-02-11 | 南京衡杰生物科技有限公司 | 作为雄激素受体拮抗剂的二芳基乙内酰脲化合物及其应用 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104211683B (zh) * | 2013-05-29 | 2017-01-11 | 成都海创药业有限公司 | 咪唑二酮类化合物及其用途 |
-
2016
- 2016-07-28 CN CN201610609034.XA patent/CN106432090B/zh active Active
- 2016-08-17 WO PCT/CN2016/095647 patent/WO2017071375A1/zh active Application Filing
- 2016-09-07 TW TW105128872A patent/TWI638810B/zh active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103159680A (zh) * | 2011-12-14 | 2013-06-19 | 爱美尼迪药物有限公司 | 咪唑二酮类化合物及其用途 |
CN104341352A (zh) * | 2013-08-09 | 2015-02-11 | 南京衡杰生物科技有限公司 | 作为雄激素受体拮抗剂的二芳基乙内酰脲化合物及其应用 |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019218979A1 (zh) * | 2018-05-14 | 2019-11-21 | 成都海创药业有限公司 | 一种hc-1119制剂及其制备方法和用途 |
JP2021523195A (ja) * | 2018-05-14 | 2021-09-02 | ヒノバ ファーマシューティカルズ インコーポレイテッド | Hc−1119製剤及びその製造方法と使用 |
JP7301883B2 (ja) | 2018-05-14 | 2023-07-03 | ヒノバ ファーマシューティカルズ インコーポレイテッド | Hc-1119製剤及びその製造方法と使用 |
Also Published As
Publication number | Publication date |
---|---|
TWI638810B (zh) | 2018-10-21 |
CN106432090B (zh) | 2019-08-20 |
WO2017071375A1 (zh) | 2017-05-04 |
TW201714878A (zh) | 2017-05-01 |
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Application publication date: 20170222 Assignee: Sichuan Haisco Pharmaceutical Co.,Ltd. Assignor: Chengdu SeaBird pharmaceutcal corporation, Ltd Contract record no.: 2017510000037 Denomination of invention: Crystal form of deuteration imidazolone compound and preparation method and use of crystal form License type: Exclusive License Record date: 20171114 |
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Address after: No.2 and No.3, floor 4, building 1, Rongyao building, No.5 Keyuan South Road, high tech Zone, Chengdu, Sichuan 610000 Patentee after: Haichuang Pharmaceutical Co., Ltd Address before: 801, C1 incubation building, Tianfu Life Science Park, 88 Keyuan South Road, high tech Zone, Chengdu, Sichuan 610000 Patentee before: Chengdu Haichuang Pharmaceutical Co.,Ltd. |
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Assignee: SICHUAN HAISCO PHARMACEUTICAL Co.,Ltd. Assignor: Chengdu Haichuang Pharmaceutical Co.,Ltd. Contract record no.: 2017510000037 Date of cancellation: 20210312 |
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