CN106405610A - Cherenkov event induction optoelectronic pulse digitizing method and apparatus - Google Patents
Cherenkov event induction optoelectronic pulse digitizing method and apparatus Download PDFInfo
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Abstract
Provided is a Cherenkov event induction optoelectronic pulse digitizing method. The method includes the steps of obtaining a pulse data set for the photon emitted in a Cherenkov event; obtaining a pulse data set of the background light; calculating the joint likelihood probability function of each time period data set for the background light and Cherenkov light; and determining whether the data set of the time period is background light or Cherenkov light. Provided is a Cherenkov event induction optoelectronic pulse digitizing apparatus including a Cherenkov event emitted photon data set acquisition module, a background photon data set acquisition module, a time period sample likelihood probability function or posteriori probability function calculation module, and an event classifier module. The Cherenkov event induction optoelectronic pulse digitizing method and apparatus can effectively improve the resolution, device sensitivity and imaging signal to noise ratio for the decay event detection, and are particularly suitable for the application of Cherenkov effect in biomedical imaging and non-destructive testing of transparent media.
Description
Technical field
The present invention relates to Digital Signal Processing, Photoelectric Signal Processing and nuclear detection field, Cherenkov's event induction photoimpact digitizing solution of more particularly, to a kind of Single Photon Time Resolved Spectrometer and device.
Background technology
When Cherenkov's event induces the object that photoimpact digitized is to generation Cherenkov's event to carry out Cherenkov's incident detection, need the various events detecting to be classified, to filtering other kinds of event.And so that the Cherenkov's event detecting can be linked together with certain biological biochemistry distribution of object, realize the imaging for radionuclide or detection by quantitative.
For above-mentioned technical problem it is necessary to for the single photon temporal information that can obtain, provide a kind of new Cherenkov's event induction photoimpact digitizing solution and device.Cherenkov's event method of sampling based on single photon, in earliest stages, Cherenkov's event can be digitized, retain Cherenkov's event information the most original, and then can farthest separate with other kinds of event, the self-luminous event particularly existing in organism.
Have benefited from the development of igh-speed wire-rod production line method and super large-scale integration, capturing single photon has been no longer impassable technical barrier.By PMT（Photomultiplier Tube）、SiPM
(Silicon Photomultiplier)、APD（Avalanche Photo Detector）Deng photoelectric device, it is possible to achieve the accurate capture to single photon signal, and the information such as output waveform, time and energy.
Content of the invention
In view of this, it is an object of the invention to provide a kind of Cherenkov's event induction photoimpact digitizing solution and device, the method and device can read the signal of telecommunication sample of multiple photons of Cherenkov's event effectively, met and number of photons strobe window by the multi-photon time, reject self-luminous event, increase reconstructed image signal to noise ratio, it is to avoid the impact to read output signal for the baseline drift.
For achieving the above object, the present invention provides following technical scheme：
A kind of Cherenkov's event induces photoimpact digitizing solution, and it includes step：
S1：Obtain the pulse data collection of Cherenkov's event emission photon（Time, position, wavelength, pulse height, pulse shape one or several）；
S2：Obtain the pulse data collection of bias light（Time, position, wavelength, pulse height, pulse shape one or several）；
S3：Calculate the joint likelihood probability function to bias light and Cherenkov light for each time segment data set；
S4：It is bias light or Cherenkov light by the data set that maximum-likelihood criterion or maximum posteriori criterion judge this time period.
Preferably, in above-mentioned Cherenkov's event induction photoimpact digitizing solution, described Cherenkov's single event refers to that single radiosiotope atomic nucleus transmitting charged particle occurs Cerenkov effect in media as well.
Preferably, in above-mentioned Cherenkov's event induction photoimpact digitizing solution, described monochromatic light subevent refers to that single visible ray that organism sent by self-luminous or Cherenkov's event or soft ultraviolet light photons hit the absorbed event of photoelectric device.
Preferably, in above-mentioned Cherenkov's event induction photoimpact digitizing solution, the described time meets and refers to multiple single photons（No less than 5）Event is in a short period of time（Such as 5 ns）Occur, that is, think that this multiple monochromatic light subevent belongs to Cherenkov's single event.
Preferably, in above-mentioned Cherenkov's event induction photoimpact digitizing solution, in the relative position of in the hole, described photon refers to that the relative position in detector module in the hole for the photon, this relative position and ray incident angle have direct relation.
Preferably, in above-mentioned Cherenkov's event induction photoimpact digitizing solution, the position that described Cherenkov's event occurs refers to position in organism for nucleic during nucleic transmitting charged particle, and the relative position that diverse location injects the photographic hole of detector is different.
A kind of Cherenkov's event induces photoimpact digitalizer, obtain module including Cherenkov's event emission photonic data collection, background photon data set obtains module, the likelihood probability function of time period sample or posterior probability function computation module, event classifier module, wherein
Cherenkov's event emission photonic data collection obtains module, for obtaining the pulse data collection of Cherenkov's event emission photon（Time, position, wavelength, pulse height, pulse shape one or several）；
Background photon data set obtains module, for obtaining the pulse data collection of bias light（Time, position, wavelength, pulse height, pulse shape one or several）；
The likelihood probability function of time period sample or posterior probability function computation module, for calculating the joint likelihood probability function to bias light and Cherenkov light for each time segment data set；
Event classifier module, is bias light or Cherenkov light by the data set that maximum-likelihood criterion or maximum posteriori criterion judge this time period.
From technique scheme it can be seen that, photoimpact digitizing solution and device are induced by the Cherenkov's event using the present invention, the imaging signal to noise ratio of device can be effectively improved, resist biological tissue's self-luminous impact, be particularly suitable for the less demanding living imaging of the imaging depths such as toy.
Compared with prior art, the invention has the beneficial effects as follows：
（1）Resist bias light and the organism self luminous time meets design, advantageously reduce the background noise of imaging；
（2）Total event reads design and can comprehensively read the multidimensional information that Cherenkov's event is enriched：Angle（2-D）, the time (1-D), position (3-D), energy (1-D).It is specially the signal of telecommunication of record photoelectric device in the form of event.
Brief description
In order to be illustrated more clearly that the embodiment of the present invention or technical scheme of the prior art, the accompanying drawing of required use in embodiment or description of the prior art will be briefly described below, apparently, accompanying drawing for the present invention in describing below is only some embodiments of the present invention, for those of ordinary skill in the art, on the premise of not paying creative work, can also obtain other accompanying drawings according to these accompanying drawings.
Fig. 1 is the flow chart of Cherenkov's event induction photoimpact digitizing solution of Single Photon Time Resolved Spectrometer of the present invention.
Fig. 2 is the structure drawing of device of Cherenkov's event induction photoimpact digitalizer of Single Photon Time Resolved Spectrometer of the present invention.
Fig. 3 is the detector module of Cherenkov's event induction photoimpact digitalizer of the present invention.
Fig. 4 is that Cherenkov's event of the present invention induces photoimpact digitized Double exponential pulse model.
Fig. 5 is that Cherenkov's event of the present invention induces the digitized three exponential pulse models of photoimpact.
Fig. 6 is that Cherenkov's event of the present invention induces photoimpact digitized Landau impulse model.
Fig. 7 is that Cherenkov's event of the present invention induces the digitized straight line of photoimpact-exponential pulse model.
Fig. 8 is the present invention typical bivariate pulse classification schematic diagram.
Fig. 9 is the present invention typical bivariate pulse classification intensity schematic diagram.
Figure 10 is the time variable pulse classification intensity schematic diagram of the present invention.
Specific embodiment
The invention discloses a kind of Cherenkov's event induction photoimpact digitizing solution of Single Photon Time Resolved Spectrometer and device, the method and device can be effectively realized the labelling of the event time of advent, the temporal resolution of hoisting module and device.
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is described in detail it is clear that described embodiment is only a part of embodiment of the present invention, rather than whole embodiments.Based on the embodiment in the present invention, the every other embodiment that those of ordinary skill in the art are obtained on the premise of not making creative work, broadly fall into the scope of protection of the invention.
As shown in Figure 1, Cherenkov's event of Single Photon Time Resolved Spectrometer disclosed by the invention induces photoimpact digitizing solution and device to pass through to gather single photon signal with the data mode of event, the recycling time meets the position screening out Cherenkov's event with estimation theory, and specific method and step is：
S1：Obtain the pulse data collection of Cherenkov's event emission photon（Time, position, wavelength, pulse height, pulse shape one or several）；
S2：Obtain the pulse data collection of bias light（Time, position, wavelength, pulse height, pulse shape one or several）；
S3：Calculate the joint likelihood probability function to bias light and Cherenkov light for each time segment data set；
S4：It is bias light or Cherenkov light by the data set that maximum-likelihood criterion or maximum posteriori criterion judge this time period.
In Cherenkov's event induction photoimpact digitalizer of above Single Photon Time Resolved Spectrometer, described Cherenkov's single event refers to that single radiosiotope atomic nucleus transmitting charged particle occurs Cerenkov effect in media as well..
In Cherenkov's event induction photoimpact digitalizer of above Single Photon Time Resolved Spectrometer, described monochromatic light subevent refers to that single visible ray that organism sent by self-luminous or Cherenkov's event or soft ultraviolet light photons hit the absorbed event of photoelectric device.
In Cherenkov's event induction photoimpact digitalizer of above Single Photon Time Resolved Spectrometer, the described time meets and refers to multiple single photons（No less than 5）Event is in a short period of time（Such as 5ns）Occur, that is, think that this multiple monochromatic light subevent belongs to Cherenkov's single event.
In Cherenkov's event induction photoimpact digitalizer of above Single Photon Time Resolved Spectrometer, in the relative position of in the hole, described photon refers to that the relative position in detector module in the hole for the photon, this relative position and ray incident angle have direct relation.
In Cherenkov's event induction photoimpact digitalizer of above Single Photon Time Resolved Spectrometer, the position that described Cherenkov's event occurs refers to position in organism for nucleic during nucleic transmitting charged particle, and the relative position that diverse location injects the photographic hole of detector is different.
In Cherenkov's event induction photoimpact digitalizer of above Single Photon Time Resolved Spectrometer, the photographic hole of described detector refers to the poroid geometry being built on detector base, and this some holes is used for determining the position that Cerenkov radiation occurs.
As shown in Figure 2, Cherenkov's event induction photoimpact digitalizer of Single Photon Time Resolved Spectrometer disclosed by the invention, it includes, and Cherenkov's event emission photonic data collection obtains module 100, background photon data set obtains module 200, the likelihood probability function of time period sample or posterior probability function computation module 300, event classifier module 400, wherein
Cherenkov's event emission photonic data collection obtains module 100, for obtaining the pulse data collection of Cherenkov's event emission photon（Time, position, wavelength, pulse height, pulse shape one or several）；
Background photon data set obtains module 200, for obtaining the pulse data collection of bias light（Time, position, wavelength, pulse height, pulse shape one or several）；
The likelihood probability function of time period sample or posterior probability function computation module 300, for calculating the joint likelihood probability function to bias light and Cherenkov light for each time segment data set；
Event classifier module 400, is bias light or Cherenkov light by the data set that maximum-likelihood criterion or maximum posteriori criterion judge this time period.
Fig. 3 is the detector module of Cherenkov's event induction photoimpact digitalizer of the present invention.Fig. 4 is that Cherenkov's event of the present invention induces photoimpact digitized Double exponential pulse model.Fig. 5 is that Cherenkov's event of the present invention induces the digitized three exponential pulse models of photoimpact.Fig. 6 is that Cherenkov's event of the present invention induces photoimpact digitized Landau impulse model.Fig. 7 is that Cherenkov's event of the present invention induces the digitized straight line of photoimpact-exponential pulse model.Fig. 8 is the present invention typical bivariate pulse classification schematic diagram.Fig. 9 is the present invention typical bivariate pulse classification intensity schematic diagram.Figure 10 is the time variable pulse classification intensity schematic diagram of the present invention.In conjunction with Fig. 3, Fig. 4 and Figure 10, by several specific embodiments, Cherenkov's event induction photoimpact digitizing solution of Single Photon Time Resolved Spectrometer of the present invention is described further with device.Cherenkov's event induction photoimpact digitizing solution of Single Photon Time Resolved Spectrometer proposed by the present invention and device, the parameter that it is related to, wave filter design, the time meets process needs and is adjusted to reach good Cerenkov radiation resolution performance and shorter pulse duration according to the feature obtaining data.List the parameter of involved Application Example processing data herein.
Example 1：
List the parameter of the present embodiment processing data herein：
Step（1）Actual device used is using camera bellows a size of 1.4m × 1.4m × 1.0m.Penetrate the positron annihilation gammaphoton 18F-FDG that source is 511kev, using the enhanced silicon photomultiplier of HONGGUANG, detector adopts circulus；
Step（2）Unloaded 24 hours, obtain background data；
Step（3）Meeting the time is about 2ns, meets and judges to meet process using the time of off-line type；
Step（4）Using Cherenkov's event reconstruction method of parsing, directly draw time and the position of Cherenkov.
Example 2：
List the parameter of this application example 2 processing data herein：
Step（1）Actual device used is using camera bellows a size of 1.8m × 1.8m × 1.8m.Penetrate the 124I-NaI that source is 511kev, using the enhanced silicon photomultiplier of HONGGUANG, detector adopts circulus；
Step（2）Unloaded 72 hours, obtain background data；
Step（3）Meeting the time is about 10ns, meets and judges to meet process using the online time；
Step（4）Using Cherenkov's event reconstruction method of iteration, the approximant time drawing Cherenkov and position, iteration 200 times.
Methods and apparatus of the present invention can be used for radiating the nuclear technology of charged corpuscle, including nuclear detection, kernel analysis, Nuclear medical instruments.
In Cherenkov's event induction photoimpact digitizing solution disclosed by the invention, the isotope that injection can launch charged particle can be used for the biochemistry in labelling organism and physiological process；Read charged particle and send the photon counting of Cherenkov's photon directive detector module and the time of each counting；The time of carrying out time read is met；The position that Cherenkov's event occurs is estimated in the relative position of in the hole by photon；The position and time of the Cherenkov estimating is rebuild, obtains the distribution of nucleic.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, and without departing from the spirit or essential characteristics of the present invention, the present invention can be realized in other specific forms.Therefore, no matter from the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is limited by claims rather than described above, it is intended that all changes in the implication and scope of the equivalency of claim that fall are included in the present invention.Any reference in claim should not be considered as limiting involved claim.
In addition, it should be understood that, although this specification is been described by according to embodiment, but not each embodiment only comprises an independent technical scheme, this narrating mode of description is only for clarity, those skilled in the art should using description as an entirety, the technical scheme in each embodiment can also through appropriately combined, formed it will be appreciated by those skilled in the art that other embodiment.
Claims (6)
1. a kind of Cherenkov's event induction photoimpact digitizing solution it is characterised in that：Including step：
S1：Obtain the pulse data collection of Cherenkov's event emission photon（Time, position, wavelength, pulse height, pulse shape one or several）；
S2：Obtain the pulse data collection of bias light（Time, position, wavelength, pulse height, pulse shape one or several）；
S3：Calculate the joint likelihood probability function to bias light and Cherenkov light for each time segment data set；
S4：It is bias light or Cherenkov light by the data set that maximum-likelihood criterion or maximum posteriori criterion judge this time period.
2. a kind of Cherenkov's event induction photoimpact digitizing solution according to claim 1 it is characterised in that：Obtain the pulse data collection of Cherenkov's event emission photon（Time, position, wavelength, pulse height, pulse shape one or several）.
3. a kind of Cherenkov's event induction photoimpact digitizing solution according to claim 1 it is characterised in that：Obtain the pulse data collection of bias light（Time, position, wavelength, pulse height, pulse shape one or several）.
4. Cherenkov's event according to claim 1 induction photoimpact digitizing solution it is characterised in that：Calculate the joint likelihood probability function to bias light and Cherenkov light for each time segment data set.
5. Cherenkov's event according to claim 1 induction photoimpact digitizing solution it is characterised in that：It is bias light or Cherenkov light by the data set that maximum-likelihood criterion or maximum posteriori criterion judge this time period.
6. a kind of Cherenkov's event induction photoimpact digitalizer it is characterised in that：Cherenkov's event emission photonic data collection obtains module, background photon data set obtains module, the likelihood probability function of time period sample or posterior probability function computation module, event classifier module, wherein,
Cherenkov's event emission photonic data collection obtains module, for obtaining the pulse data collection of Cherenkov's event emission photon（Time, position, wavelength, pulse height, pulse shape one or several）；
Background photon data set obtains module, for obtaining the pulse data collection of bias light（Time, position, wavelength, pulse height, pulse shape one or several）；
The likelihood probability function of time period sample or posterior probability function computation module, for calculating the joint likelihood probability function to bias light and Cherenkov light for each time segment data set；
Event classifier module, is bias light or Cherenkov light by the data set that maximum-likelihood criterion or maximum posteriori criterion judge this time period.
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| CN108090936A (en) * | 2017-12-17 | 2018-05-29 | 北京工业大学 | The scanning mating plate tomograph imaging method of Qie Lunkefu fluorescence excitations |
| CN109975854A (en) * | 2017-12-27 | 2019-07-05 | 同方威视技术股份有限公司 | Method and system for pulse shape discriminator |
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