CN106390049A - Extraction method for Jiawei xiaoyao san, radix angelicae pubescentis-viscum coloratum decoction prescription, meridian collateral dredging and blood circulation activation decoction prescription, and blood vessel stasis removing decoction prescription - Google Patents
Extraction method for Jiawei xiaoyao san, radix angelicae pubescentis-viscum coloratum decoction prescription, meridian collateral dredging and blood circulation activation decoction prescription, and blood vessel stasis removing decoction prescription Download PDFInfo
- Publication number
- CN106390049A CN106390049A CN201510455059.4A CN201510455059A CN106390049A CN 106390049 A CN106390049 A CN 106390049A CN 201510455059 A CN201510455059 A CN 201510455059A CN 106390049 A CN106390049 A CN 106390049A
- Authority
- CN
- China
- Prior art keywords
- radix
- prescription
- decoction
- grams
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to an extraction method for a Jiawei xiaoyao san prescription, a radix angelicae pubescentis-viscum coloratum decoction prescription, a meridian collateral dredging and blood circulation activation decoction prescription, and a blood vessel stasis removing decoction prescription. The extraction method comprises: (a) respectively carrying out steam distillation on angelica sinensis, ligusticum chuanxiong hort, outer-coarse-skin-removed cortex cinnamomi, and roasted ginger in the prescription for 1-3 h with a mixture comprising 85-90 wt% of ethanol and 10-15 wt% of water; (b) respectively extracting cortex moutan, licorice root, ginseng, radix bupleuri, gardenia jasminoides, cynanchum otophyllum, radix paeoniae rubra, semen persicae, platycodon grandiflorus, and clematis chinensis osbeck in the prescription for 1-3 h with a mixture comprising 10-30 wt% of ethanol and 70-90 wt% of water; (c) respectively extracting peppermint and asarum sieboldii miq in the prescription for 5-30 min with water; (d) respectively extracting herbs excluded in the steps (a)-(c) for 1-3 h with water twice; and (e) merging the extracts in the steps (a)-(d).
Description
Technical field
The present invention with regard to a kind of extracting process of prescription, particularly a kind of with regard to JIAWEI XIAOYAO SAN, Radix Angelicae Pubescentis et Herba Taxilli Decoction,
Dredge the extracting process through blood activating decoction and decoction for removing blood stasis prescription.
Background technology
The history of the existing thousands of years of Chinese medicine development, in Chinese medicine, contained chemical composition is sufficiently complex, has both contained multiple
Effective ingredient, also contains invalid components it is also possible to comprise toxic component.Extract its effective ingredient and add further
With separation, purification, obtain the important content that effective monomer is in Chinese medicine research field.Chinese medicine extraction is exactly
Extract wherein effective ingredient using some technology to greatest extent so that the inherent quality of Chinese medicine preparation and clinical treatment
Effect improves, and so that the effect of Chinese medicine is played to greatest extent, the extraction of Chinese medicine is the important ring of production process
Section, its process, the selection of technological process and device configuration all will be directly connected to quality and the clinic of Chinese medicine
Effect.
According to《Dialectical record》, the common usage of JIAWEI XIAOYAO SAN is to be decocted in water for oral dose；According to《Essential Recipes for Emergent Use Worth A Thousand Gold》,
The common usage of Radix Angelicae Pubescentis et Herba Taxilli Decoction is to be struggled against with water 1, boils and takes 3 liters, point 3 clothes；According to《The side of copying of Wan Shi family》, dredge
Common usage through blood activating decoction is to be decocted in water for oral dose；According to《The correction of the errors of medical works》, the common usage of decoction for removing blood stasis is
To be decocted in water for oral dose.
Content of the invention
It is an object of the invention to, a kind of JIAWEI XIAOYAO SAN, Radix Angelicae Pubescentis et Herba Taxilli Decoction are provided, dredge through blood activating decoction and blood
The extracting process of mansion removing blood stasis decoction side, carries out, to solve prior art, its own shortcomings that Chinese medicine extraction has：Chinese medicine
In loss of effective components, especially wherein non-water-soluble composition；Non-active ingredients can not be with to greatest extent
Remove, enrichment factor is not high enough；In extracting solution in addition to effective ingredient, often impurity is more, still has a small amount of water solublity
Paste property composition, is often unfavorable for refining；And excessively high-temperature operation can cause a large amount of decomposition of thermal sensitivity effective ingredient.
For solving the above problems, inventors have surprisingly discovered that a kind of JIAWEI XIAOYAO SAN, Radix Angelicae Pubescentis et Herba Taxilli Decoction, dredge through work
Blood soup and the extracting process of four kinds of prescriptions of decoction for removing blood stasis, it comprises the steps of：(a) by prescription work as
Return, Rhizoma Chuanxiong, Cortex Cinnamomi and Roast Rhizoma Zingiberis Recens, steamed with the mixture steam of 85～90wt% ethanol and 10～15wt% water respectively
Evaporate 1～3 hour；(b) by the Cortex Moutan in prescription, Radix Glycyrrhizae, Radix Ginseng, Radix Bupleuri, SHANZHIZI, the Radix Paeoniae Alba, Radix Paeoniae Rubra,
Semen Persicae, Radix Platycodoniss and Radix Clematidis, extract 1～3 with the mixture of 10～30wt% ethanol and 70～90wt% water respectively
Hour；C () is by the Herba Menthae in prescription and Herba Asari respectively with water extraction 5～30 minutes；(d) by above-mentioned steps (a)～
C the medical material beyond (), respectively with water extraction 1～3 hour, is repeated twice；E () is by above-mentioned steps (a)～(d)
Extract merges.
In a preferred embodiment, the prescription of wherein this JIAWEI XIAOYAO SAN is Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Bupleuri, white,
Cortex Moutan, Poria, Roast Rhizoma Zingiberis Recens, Herba Menthae, Radix Glycyrrhizae Preparata and SHANZHIZI.
In another preferred embodiment, wherein this Radix Angelicae Pubescentis et Herba Taxilli Decoction prescription be Radix Angelicae Pubescentiss, parasitism, Radix Ginseng, Poria,
Radix Glycyrrhizae, Radix Rehmanniae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, the Radix Paeoniae Alba, Radix Saposhnikoviae, Radix Gentianae Macrophyllae, Herba Asari, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Cortex Cinnamomi.
In another preferred embodiment, the prescription that wherein this dredges through blood activating decoction is Radix Glycyrrhizae, Radix Angelicae Sinensis, the Radix Paeoniae Alba, the Radix Rehmanniae
Yellow, grey, Radix Achyranthis Bidentatae, Pericarpium Citri Reticulatae, Semen Persicae, Radix Clematidis, Rhizoma Chuanxiong, Radix Stephaniae Tetrandrae, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Radix Gentianae,
Poria, Rhizoma Zingiberis Recenss.
In another preferred embodiment, the prescription of wherein this decoction for removing blood stasis is Radix Angelicae Sinensis, Radix Rehmanniae, Semen Persicae, red
Flower, Fructus Aurantii, Radix Paeoniae Rubra, Radix Bupleuri, Radix Glycyrrhizae, Radix Platycodoniss, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae.
In another preferred embodiment, wherein this step (a) system is steamed with the mixture of 90wt% ethanol and 10wt% water
Steam distillation 1 hour.
In another preferred embodiment, wherein this step (b) system is carried with the mixture of 30wt% ethanol and 70wt% water
Take 1 hour.
In another preferred embodiment, wherein this step (c) system extracts 10 minutes.
In another preferred embodiment, wherein this step (d) system extracts 1 hour.
In another preferred embodiment, it comprises step (f) further by mixture pelleting.
Inventor finds, using above-mentioned JIAWEI XIAOYAO SAN, Radix Angelicae Pubescentis et Herba Taxilli Decoction, dredges through blood activating decoction and blood mansion
The extract that the extracting process of removing blood stasis decoction side is obtained, has the effective ingredient of high level.
Specific embodiment
The terms " one " or " a kind of " when being used in conjunction in claim or description with "comprising",
May represent has one, but also complies with " one or more " or " at least one ".
System of the present invention provides a kind of JIAWEI XIAOYAO SAN, Radix Angelicae Pubescentis et Herba Taxilli Decoction, dredges through blood activating decoction and decoction for removing blood stasis four
Plant the extracting process of prescription, it comprises the steps of：(a) by the Radix Angelicae Sinensis in prescription, Rhizoma Chuanxiong, Cortex Cinnamomi and Roast Rhizoma Zingiberis Recens,
Respectively with the mixture steam distillation 1～3 hour of 85～90wt% ethanol and 10～15wt% water；B () is by prescription
In Cortex Moutan, Radix Glycyrrhizae, Radix Ginseng, Radix Bupleuri, SHANZHIZI, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Semen Persicae, Radix Platycodoniss and Radix Clematidis,
Extracted 1～3 hour with the mixture of 10～30wt% ethanol and 70～90wt% water respectively；C () will be thin in prescription
Lotus and Herba Asari are respectively with water extraction 5～30 minutes；(d) by the medical material beyond above-mentioned steps (a)～(c), respectively with
Water extraction 1～3 hour, is repeated twice；E above-mentioned steps (a)～(d) extract is merged by ().
From the foregoing, the method for the present invention can be applicable to Radix Stephaniae Tetrandrae Radix Astragali soup, GEGEN TANG, guizhi decoction and Radix Glycyrrhizae Preparata
Decoction side, whether the enforcement of each step in method, depending on the medical material having in each prescription.
For example, it is an aspect of the invention to providing a kind of extracting process of JIAWEI XIAOYAO SAN prescription, wherein this medicine
Side is including but not limited to Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Bupleuri, white, Cortex Moutan, Poria, Roast Rhizoma Zingiberis Recens, Herba Menthae, Radix Glycyrrhizae Preparata
And SHANZHIZI.
Additionally, above-mentioned steps (d) more can be separately added into following prescription, blood deficiency consumptive fever according to following symptom：Plus river
Rhizome of chuanxiong, Radix Rehmanniae；Deficiency of vital energy body is tired：Plus Radix Ginseng, Radix Astragali；Stagnation of liver-QI very hypochondriac pain：Perfuming is attached, Radix Curcumae；Dysmenorrhoea：Plus prolong
Rhizoma Corydalis, the Radix Aucklandiae, Herba Leonuri；Blood stasis：Plus Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Flos Carthami；Intenseness of heat：Plus the Radix Rehmanniae, Cortex Lycii；Spleen
Empty loose stool：Plus Radix Codonopsis, Rhizoma Dioscoreae, Semen Coiciss；The deficiency of YIN：Close LIUWEI DIHUANG WAN；Dermatosiss：Plus Cortex Lycii, chaste tree
Mustard；Difficulty and pain in micturition：Plus Semen Plantaginiss.
Another aspect of the invention is to provide a kind of extracting process of Radix Angelicae Pubescentis et Herba Taxilli Decoction prescription, this Radix Angelicae Pubescentis et Herba Taxilli Decoction
Prescription including but not limited to Radix Angelicae Pubescentiss, parasitism, Radix Ginseng, Poria, Radix Glycyrrhizae, Radix Rehmanniae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, white
Chinese herbaceous peony, Radix Saposhnikoviae, Radix Gentianae Macrophyllae, Herba Asari, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Cortex Cinnamomi.
Additionally, above-mentioned steps (d) more can be separately added into following prescription according to following symptom, pain is more acute：Plus ground
Dragon, Flos Carthami, Semen Strychni；Cold-evil contains partially：Plus Radix Aconiti Lateralis Preparata, Rhizoma Zingiberiss；Damp is contained partially：Plus it is Radix Stephaniae Tetrandrae, grey；Lumbago
Like folding：Plus Radix Dipsaci, Rhizoma Cibotii, Semen Cuscutae.
Another aspect of the invention is to provide a kind of extracting process dredged through blood activating decoction prescription, this Radix Angelicae Pubescentis et Herba Taxilli Decoction
Prescription including but not limited to Radix Glycyrrhizae, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Rehmanniae, grey, Radix Achyranthis Bidentatae, Pericarpium Citri Reticulatae, Semen Persicae, prestige
Radix Clematidis, Rhizoma Chuanxiong, Radix Stephaniae Tetrandrae, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Radix Gentianae, Poria, Rhizoma Zingiberis Recenss.
Additionally, above-mentioned steps (d) more can be separately added into following prescription according to following symptom, hold expectorant under the arm：Plus Rhizoma Arisaematis,
The Rhizoma Pinelliae；Upper body brachialgia：Plus Ramulus Cinnamomi, Rhizoma Curcumae Longae；Lower part of the body pain in foot：Plus Fructus Chaenomeliss, Caulis Akebiae, Cortex Phellodendri, Semen Coiciss；Gas
Empty：Plus Radix Ginseng, white, Carapax et Plastrum Testudiniss；Blood deficiency：Times SIWU TANG adds Colla Corii Asini, Radix Salviae Miltiorrhizae, Sucus Zingberis.
Another aspect of the invention is to provide a kind of extracting process of decoction for removing blood stasis prescription, this decoction for removing blood stasis
Prescription including but not limited to Radix Angelicae Sinensis, Radix Rehmanniae, Semen Persicae, Flos Carthami, Fructus Aurantii, Radix Paeoniae Rubra, Radix Bupleuri, Radix Glycyrrhizae, Radix Platycodoniss,
Rhizoma Chuanxiong, Radix Achyranthis Bidentatae.
Additionally, above-mentioned steps (d) more can be separately added into following prescription, blood stasis dysmenorrhoea, amenorrhea according to following symptom
Person：Go that Radix Platycodoniss perfuming is attached, Herba Lycopi, Herba Leonuri；Cardiopalmus, insomniac：Plus Poria cum Radix Pini, Fructus Schisandrae Chinensis, Semen Ziziphi Spinosae；
Purplish tongue, hesitant pulse person：Plus Radix Salviae Miltiorrhizae, Radix Notoginseng；The person that has lump under the side of body：Plus Radix Curcumae, Radix Salviae Miltiorrhizae, Pericarpium Citri Reticulatae Viride；Dry thirsty person：
Plus Radix Trichosanthis, Radix Scrophulariae；Fever patient：Plus Flos Lonicerae, Fructus Forsythiae；Yellowish or reddish urine person：Plus Rhizoma Coptidis, Rhizoma Imperatae；Big constipation
Knot person：Increase yellow, Natrii Sulfas.
In above-mentioned extracting process, filter after preferably being further contained in each (a)～(d) step.
In above-mentioned extracting process, preferably can further comprise step (f) by mixture pelleting.
Above-mentioned term " extraction " is to extract wherein effective ingredient to greatest extent so that Chinese medicine using some technology
The inherent quality of preparation and clinical therapeutic efficacy improve, and so that the effect of Chinese medicine is played to greatest extent.Chinese medicine
Extraction be Chinese Traditional Medicine important unit operation, its process, the selection of technological process and equipment are joined
Put and all will be directly connected to quality and the clinical effectiveness of Chinese medicine.
In the present invention, Chinese medicine containing volatile oil, such as Radix Angelicae Sinensis, Ramulus Cinnamomi, Rhizoma Zingiberis Recenss, Rhizoma Chuanxiong, Cortex Cinnamomi, Roast Rhizoma Zingiberis Recens
Deng, wherein this volatile oil also known as quintessence oil, it is one to there are volatility, the oily liquids that can go out with vapor distillation,
There is fragrance, and this volatile oil is the polytype such as aliphatic compound, aromatic compound note class compound
The mixture of compound, inventors be surprised to learn that this volatile oil Chinese medicine preferably system is extracted to have volatile solution
Take, more preferably but the mixture that is not limited to mix with the ratio of 90wt% ethanol and 10wt% water with ethanol and water
Steam extraction.
In the present invention, containing tcm with glycosides, such as Radix Et Rhizoma Rhei, Cortex Moutan, Radix Glycyrrhizae, Semen Armeniacae Amarum, Radix Ginseng, Radix Astragali, bavin
Recklessly, SHANGZI, Semen Persicae, Radix Paeoniae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Radix Platycodoniss, Radix Clematidis etc., mostly have colourless, odorless,
Tool bitterness, minority is coloured, minority has the feature of sweet taste, and most in neutral or acid, minority is in alkalescence, big
Most of soluble in water and ethanol, easily generated sugar and aglycon by diluted acid or enzyme hydrolysiss, typically has certain optics and lives
Property, inventors be surprised to learn that the above-mentioned preferably system containing tcm with glycosides is extracted with the mixture of ethanol and water, its ratio is relatively
Good system is with the water of the ethanol mixing 70wt% of 30wt%.
In the present invention, Chinese medicine containing alkaloidss, such as Radix Aconiti Lateralis Preparata, Rhizoma Coptidis, Cortex Phellodendri, Herba Ephedrae, the Rhizoma Pinelliae etc., mostly
Number alkaloids are crystal material, colourless and have optical activity, inventors be surprised to learn that above-mentioned containing in alkaloidss
Medicine preferably system is extracted with the mixture of ethanol and water, and its ratio preferably system is with the water of the ethanol of 70wt% and 30wt%.
In the present invention, Olibanum, Myrrha, Sanguis Draxonis etc., preferably system are extracted 30 minutes with ethanol.
In the present invention, the Chinese medicine such as Os Draconis, Concha Ostreae, preferable system extracts by the way of boiling, the time preferably 2～4
Hour, most preferably 3 hours.
In the present invention, Colla cornus cervi, Colla Corii Asini, Testudiniss angle glue, Borneolum Syntheticum etc., preferably system, without extraction, direct plunge into height
In warm solution, the mixture of the extract of prescription that this pyrosol can extract for other.
In the present invention, Herba Menthae, Herba Asari etc., preferably system, with water extraction 5～30 minutes, are more preferably with water extraction 10
Minute.
Medical material in addition to above-mentioned enumerating in the present invention, preferably system, with water extraction 1 hour, merge after being repeated twice.
If Chinese medicine washes with water before extracting, these powder or particle can be made washed away, adjuvant and effective ingredient
Can be dissolved in water and be washed off so as to curative effect reduces, therefore before Chinese medicine extraction, handy water does not rinse, can only be with cold
Water soaks.The prepared slices of Chinese crude drugs after cold water soak, organizational structure can loose expansion, make effective ingredient easily fried,
Make effective ingredient easily fried.If using hot-water soak at the very start, in medical material, contained protein component will be very
Fast dissolution and freezing film, are wrapped in medical material surface, make moisture be not easy to penetrate in medical material histiocyte,
Effective ingredient also is difficult to decompose out, affects the fried of composition.
Traditional Chinese medicine extraction method includes decocting cooking method, infusion process, percolation, Gelatin improving method, circumfluence method, solvent
Extraction method, steam distillation and sublimed method etc..Solvent extraction method is most widely used method, and it is basis
The property of various effective ingredient dissolubility in Chinese herbal medicine, from molten to other compositions greatly to needing ingredient solubility
The little solvent of Xie Du, a kind of extracting method that required active component is dissolved out in medical material tissue.
Embodiment
Embodiment 1- utilizes the method for the present invention to extract JIAWEI XIAOYAO SAN
By take respectively in prescription 4 grams of Radix Angelicae Sinensis, 4 grams of the Radix Paeoniae Alba, 4 grams of Radix Bupleuri, white 4 grams, 2.5 grams of Cortex Moutan, Fu
4 grams of Siberian cocklebur, 4 grams of Roast Rhizoma Zingiberis Recens, 2 grams of Herba Menthae, 2 grams of Radix Glycyrrhizae Preparata and 2.5 grams of SHANZHIZI, and according to method of the present invention extraction
Take, with the extracted effective ingredient of weighing method measurement for 5 grams after extraction.
Comparative example 1- utilizes prior art method to extract JIAWEI XIAOYAO SAN
By take respectively in prescription 4 grams of Radix Angelicae Sinensis, 4 grams of the Radix Paeoniae Alba, 4 grams of Radix Bupleuri, white 4 grams, 2.5 grams of Cortex Moutan, Fu
4 grams of Siberian cocklebur, 4 grams of Roast Rhizoma Zingiberis Recens, 2 grams of Herba Menthae, 2 grams of Radix Glycyrrhizae Preparata and 2.5 grams of SHANZHIZI, and according to known decocting method extraction
Take, will all medical materials in water extraction 2 hours, with effective ingredient that the measurement of weighing method is extracted after extraction
For 3.4 grams.
Embodiment 2- utilizes the method for the present invention to extract Radix Angelicae Pubescentis et Herba Taxilli Decoction
By take respectively in prescription 3 grams of Radix Angelicae Pubescentiss, parasitic 2 grams, 2 grams of Radix Ginseng, 2 grams of Poria, 2 grams of Radix Glycyrrhizae, Radix Rehmanniae 2
Gram, 2 grams of Radix Angelicae Sinensis, 2 grams of Rhizoma Chuanxiong, 2 grams of the Radix Paeoniae Alba, 2 grams of Radix Saposhnikoviae, 2 grams of Radix Gentianae Macrophyllae, 2 grams of Herba Asari, 2 grams of the Cortex Eucommiae, cattle
2 grams of knee joint, 2 grams of Cortex Cinnamomi, and according to method of the present invention extraction, extracted with the measurement of weighing method after extraction
Effective ingredient is 4.95 grams.
Comparative example 2- utilizes prior art method extraction plus Radix Angelicae Pubescentis et Herba Taxilli Decoction
By take respectively in prescription 3 grams of Radix Angelicae Pubescentiss, parasitic 2 grams, 2 grams of Radix Ginseng, 2 grams of Poria, 2 grams of Radix Glycyrrhizae, Radix Rehmanniae 2
Gram, 2 grams of Radix Angelicae Sinensis, 2 grams of Rhizoma Chuanxiong, 2 grams of the Radix Paeoniae Alba, 2 grams of Radix Saposhnikoviae, 2 grams of Radix Gentianae Macrophyllae, 2 grams of Herba Asari, 2 grams of the Cortex Eucommiae, cattle
2 grams of knee joint, 2 grams of Cortex Cinnamomi, and according to known decocting method extraction, will all medical materials in water extraction 2 hours, extraction
With the extracted effective ingredient of weighing method measurement for 3.3 grams after taking.
Embodiment 3- utilizes method of the present invention extraction to dredge through blood activating decoction
By in prescription respectively 1.0 grams of extracting liquorice, 2.0 grams of Radix Angelicae Sinensis, 2.5 grams of the Radix Paeoniae Alba, 2.0 grams of Radix Rehmanniae, grey 2.0
Gram, 2.0 grams of Radix Achyranthis Bidentatae, 2.0 grams of Pericarpium Citri Reticulatae, 2.0 grams of Semen Persicae, 2.0 grams of Radix Clematidis, 1.0 grams of Rhizoma Chuanxiong, Radix Stephaniae Tetrandrae 1.0
Gram, 1.0 grams of Rhizoma Et Radix Notopterygii, 1.0 grams of Radix Saposhnikoviae, 1.0 grams of the Radix Angelicae Dahuricae, 1.0 grams of Radix Gentianae, 1.0 grams of Poria, 3.0 grams of Rhizoma Zingiberis Recenss,
And according to method of the present invention extraction, with the extracted effective ingredient of weighing method measurement for 4.5 grams after extraction.
Comparative example 3- utilizes prior art method extraction to dredge through blood activating decoction
By in prescription respectively 1.0 grams of extracting liquorice, 2.0 grams of Radix Angelicae Sinensis, 2.5 grams of the Radix Paeoniae Alba, 2.0 grams of Radix Rehmanniae, grey 2.0
Gram, 2.0 grams of Radix Achyranthis Bidentatae, 2.0 grams of Pericarpium Citri Reticulatae, 2.0 grams of Semen Persicae, 2.0 grams of Radix Clematidis, 1.0 grams of Rhizoma Chuanxiong, Radix Stephaniae Tetrandrae 1.0
Gram, 1.0 grams of Rhizoma Et Radix Notopterygii, 1.0 grams of Radix Saposhnikoviae, 1.0 grams of the Radix Angelicae Dahuricae, 1.0 grams of Radix Gentianae, 1.0 grams of Poria, 3.0 grams of Rhizoma Zingiberis Recenss,
And according to known decocting method extraction, will all medical materials in water extraction 2 hours, surveyed with weighing method after extraction
Measure extracted effective ingredient and be 3.0 grams.
Embodiment 4- utilizes the method for the present invention to extract decoction for removing blood stasis
By taking 4.5 grams of Radix Angelicae Sinensis, 4.5 grams of Radix Rehmanniae, 6.0 grams of Semen Persicae, 4.5 grams of Flos Carthami, Fructus Aurantii 3.0 in prescription respectively
Gram, 3.0 grams of Radix Paeoniae Rubra, 1.5 grams of Radix Bupleuri, 1.5 grams of Radix Glycyrrhizae, 2.3 grams of Radix Platycodoniss, 2.3 grams of Rhizoma Chuanxiong, 4.5 grams of Radix Achyranthis Bidentatae,
And according to method of the present invention extraction, with the extracted effective ingredient of weighing method measurement for 7.5 grams after extraction.
Comparative example 4- utilizes prior art method to extract decoction for removing blood stasis
By taking 4.5 grams of Radix Angelicae Sinensis, 4.5 grams of Radix Rehmanniae, 6.0 grams of Semen Persicae, 4.5 grams of Flos Carthami, Fructus Aurantii 3.0 in prescription respectively
Gram, 3.0 grams of Radix Paeoniae Rubra, 1.5 grams of Radix Bupleuri, 1.5 grams of Radix Glycyrrhizae, 2.3 grams of Radix Platycodoniss, 2.3 grams of Rhizoma Chuanxiong, 4.5 grams of Radix Achyranthis Bidentatae,
And according to known decocting method extraction, will all medical materials in water extraction 2 hours, surveyed with weighing method after extraction
Measure extracted effective ingredient and be 5.0 grams.
According to above-described embodiment and comparative example result it is seen that using the method for the present invention, compared to prior art
Water-boiling method, more effective ingredient can be extracted, and have preferably effect.
Claims (10)
1. a kind of JIAWEI XIAOYAO SAN, Radix Angelicae Pubescentis et Herba Taxilli Decoction, the thin extraction through blood activating decoction and four kinds of prescriptions of decoction for removing blood stasis
Take method, it comprises the steps of：
(a) by the Radix Angelicae Sinensis in prescription, Rhizoma Chuanxiong, Cortex Cinnamomi and Roast Rhizoma Zingiberis Recens, respectively with 85～90wt% ethanol and 10～15wt%
The mixture steam distillation of water 1～3 hour；
(b) by the Cortex Moutan in prescription, Radix Glycyrrhizae, Radix Ginseng, Radix Bupleuri, SHANZHIZI, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Semen Persicae,
Radix Platycodoniss and Radix Clematidis, are extracted 1～3 hour with the mixture of 10～30wt% ethanol and 70～90wt% water respectively；
C () is by the Herba Menthae in prescription and Herba Asari respectively with water extraction 5～30 minutes；
D () by the medical material beyond above-mentioned steps (a)～(c), respectively with water extraction 1～3 hour, is repeated twice；
E above-mentioned steps (a)～(d) extract is merged by ().
2. extracting process as claimed in claim 1 it is characterised in that the prescription of this JIAWEI XIAOYAO SAN be Radix Angelicae Sinensis, white
Chinese herbaceous peony, Radix Bupleuri, white, Cortex Moutan, Poria, Roast Rhizoma Zingiberis Recens, Herba Menthae, Radix Glycyrrhizae Preparata and SHANZHIZI.
3. extracting process as claimed in claim 1 is it is characterised in that the prescription of this Radix Angelicae Pubescentis et Herba Taxilli Decoction is Radix Angelicae Pubescentiss, posts
Life, Radix Ginseng, Poria, Radix Glycyrrhizae, Radix Rehmanniae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, the Radix Paeoniae Alba, Radix Saposhnikoviae, Radix Gentianae Macrophyllae, Herba Asari, the Cortex Eucommiae,
Radix Achyranthis Bidentatae and Cortex Cinnamomi.
4. extracting process as claimed in claim 1 it is characterised in that this dredge prescription through blood activating decoction be Radix Glycyrrhizae, when
Return, the Radix Paeoniae Alba, Radix Rehmanniae, grey, Radix Achyranthis Bidentatae, Pericarpium Citri Reticulatae, Semen Persicae, Radix Clematidis, Rhizoma Chuanxiong, Radix Stephaniae Tetrandrae, Rhizoma Et Radix Notopterygii, anti-
Wind, the Radix Angelicae Dahuricae, Radix Gentianae, Poria and Rhizoma Zingiberis Recenss.
5. extracting process as claimed in claim 1 is it is characterised in that the prescription of this decoction for removing blood stasis is Radix Angelicae Sinensis, life
Radix Rehmanniae, Semen Persicae, Flos Carthami, Fructus Aurantii, Radix Paeoniae Rubra, Radix Bupleuri, Radix Glycyrrhizae, Radix Platycodoniss, Rhizoma Chuanxiong and Radix Achyranthis Bidentatae.
6. extracting process as claimed in claim 1 is it is characterised in that this step (a) is with 90wt% ethanol and 10wt%
The mixture steam distillation of water 1 hour.
7. extracting process as claimed in claim 1 is it is characterised in that this step (b) is with 30wt% ethanol and 70wt%
The mixture of water extracts 1 hour.
8. extracting process as claimed in claim 1 is it is characterised in that this step (c) is extracted 10 minutes.
9. extracting process as claimed in claim 1 is it is characterised in that this step (d) is extracted 1 hour.
10. mixture is made by extracting process as claimed in claim 1 it is characterised in that comprising step (f) further
Grain.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510455059.4A CN106390049A (en) | 2015-07-30 | 2015-07-30 | Extraction method for Jiawei xiaoyao san, radix angelicae pubescentis-viscum coloratum decoction prescription, meridian collateral dredging and blood circulation activation decoction prescription, and blood vessel stasis removing decoction prescription |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510455059.4A CN106390049A (en) | 2015-07-30 | 2015-07-30 | Extraction method for Jiawei xiaoyao san, radix angelicae pubescentis-viscum coloratum decoction prescription, meridian collateral dredging and blood circulation activation decoction prescription, and blood vessel stasis removing decoction prescription |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106390049A true CN106390049A (en) | 2017-02-15 |
Family
ID=58008999
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510455059.4A Pending CN106390049A (en) | 2015-07-30 | 2015-07-30 | Extraction method for Jiawei xiaoyao san, radix angelicae pubescentis-viscum coloratum decoction prescription, meridian collateral dredging and blood circulation activation decoction prescription, and blood vessel stasis removing decoction prescription |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106390049A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1840001A (en) * | 2006-01-23 | 2006-10-04 | 重庆希尔安药业有限公司 | Method for preparing mixture with pubescent angelica root and loranthus |
-
2015
- 2015-07-30 CN CN201510455059.4A patent/CN106390049A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1840001A (en) * | 2006-01-23 | 2006-10-04 | 重庆希尔安药业有限公司 | Method for preparing mixture with pubescent angelica root and loranthus |
Non-Patent Citations (4)
| Title |
|---|
| 佚名: "舒经活血汤", 《个人图书馆》 * |
| 张群湘等: "《最佳食疗 护肝食疗》", 31 August 2014, 湖北科学技术出版社 * |
| 沈善寅等: "《临床方剂手册》", 31 March 1991, 济南出版社 * |
| 王淼: "《中华传世老偏方治病一本通》", 28 February 2014, 天津科学技术出版社 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2001514650A (en) | Essential oil composition | |
| CN102106974A (en) | Oral liquid for healing hemiplegia | |
| CN106390048A (en) | Extraction method for Xiaochaihu decoction and radix bupleuri-dragon's bone-oyster decoction | |
| US10265369B2 (en) | Topical drug for treating breast cancer and preparation method thereof | |
| CN105535448A (en) | Traditional Chinese medicine composition for treating child myasthenia gravis | |
| CN103251750B (en) | Externally applied medicinal oil for treating middle-aged and old-aged rheumatic diseases | |
| CN103372073A (en) | Red rice and hawthorn medicinal composition for regulating blood fat and preparation method of composition | |
| CN102657736B (en) | Medicament composition for treating rheumatoid arthritis and preparation method of medicament composition | |
| CN103599483A (en) | Traditional Chinese medicine formula for treating coronary heart disease | |
| CN106389798A (en) | Extraction method for ziziphus jujuba mill.var.spinosa decoction prescription and tuckahoe-cassia twig-atractylodes macrocephala koidz-licorice root decoction prescription | |
| CN100500183C (en) | Preparation of Chinese medicinal mixture for treating gynecologic menstrual disease | |
| CN106109968A (en) | Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata pharmaceutical composition and preparation method thereof | |
| CN106138772A (en) | Gastrodia tuber and fleece-flower root combined pharmaceutical composition and preparation technology thereof | |
| CN106390049A (en) | Extraction method for Jiawei xiaoyao san, radix angelicae pubescentis-viscum coloratum decoction prescription, meridian collateral dredging and blood circulation activation decoction prescription, and blood vessel stasis removing decoction prescription | |
| CN103372040B (en) | Monas cuspurpureus Went Rhizoma Chuanxiong drug regimen of a kind of adjusting blood lipid and preparation method thereof | |
| CN106389820A (en) | Extraction method for Tianwang buxin dan prescription and Shengmaiyin prescription | |
| CN1814173A (en) | Chinese herbal medicine decoction for treating B-type hepatitis and preparing method | |
| CN1175875C (en) | Medicine made of lysimachia for treating hepatobiliary calculus and its prescription | |
| CN116211945B (en) | Traditional Chinese medicine composition, preparation method thereof and application thereof in preparation of medicine for treating or preventing chronic cerebral circulation inefficiency | |
| CN106389758A (en) | Extraction method for Zuogui pill prescription and Yougui pill prescription | |
| CN106389525A (en) | Extraction method for spleen-stomach invigorating and qi replenishing decoction prescription, pinellia ternata heart-removing decoction prescription, compound salvia miltiorrhiza tablet prescription, and hemp seed pill prescription | |
| CN101966304A (en) | Medicament for freeing network vessels and activating blood and preparation method thereof | |
| CN106390050A (en) | Extraction for radix stephaniae tetrandrae-milkvetch root decoction prescription, radix puerariae decoction prescription, cassia twig decoction prescription, and radix glycyrrhizae preparata decoction prescription | |
| CN106075104A (en) | Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata combined pharmaceutical composition and preparation method thereof | |
| CN106581214A (en) | Ischemic stroke treating traditional Chinese medicine composition and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170215 |
|
| WD01 | Invention patent application deemed withdrawn after publication |