CN106389988A

CN106389988A - Medicine for treating whooping cough and preparation method thereof

Info

Publication number: CN106389988A
Application number: CN201611120006.8A
Authority: CN
Inventors: 张云侠
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-12-08
Filing date: 2016-12-08
Publication date: 2017-02-15

Abstract

The invention discloses a medicine for treating whooping cough and a preparation method thereof. The medicine is prepared mainly from folium mori, flos chrysanthemi, fructus forsythiae, scutellaria baicalensis, platycodon grandiflorum, radix paeoniae alba, radix stemonae preparata, dried orange peel, radix peucedani, bombyx batryticatus, loquat leaf, bile arisaema, radix asteris, fritillaria cirrhosa and the like in certain weight proportion. The medicine disclosed by the invention has the functions of clearing heat and moistening lung, drying dampness and dispersing phlegm and relieving cough and relieving asthma; when used for treating whooping cough, the medicine takes effect quickly, realizes a good treatment effect and avoids side effects.

Description

One kind treats pertussal medicine and preparation method thereof

Technical field

The present invention relates to one kind treats pertussal medicine and preparation method thereof, belong to the field of Chinese medicines.

Background technology

Pertussis are a kind of Acute respiratory infectious diseases being caused by bordetella pertussis, and Clinical symptoms are that cough gradually adds Weight, in typical paroxysmal, spasmodic cough, eventually profound chicken and crows sample inspiratory croup in end for cough, and the course of disease is up to 2～3 Individual month, therefore have the title of pertussis, there are many report adults to suffer from pertussis in recent years, be mainly shown as dry cough, lack paroxysmal convulsion Contraction is coughed.

Due to Western medicine cannot effective fast treating pertussis, therefore people to effectively treatment, pertussal Chinese medicine exists Greatly demand, up to now, does not also find the relevant report with regard to the present invention.

Content of the invention

The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, have found effectively treatment one hundred days finally The medicine coughed, thus complete the present invention.

It is an object of the invention to provide a kind of more effectively treat pertussal Chinese medicine composition.

Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.

Medicine of the present invention is to select Folium Mori, Flos Chrysanthemi, Fructus Forsythiae, Radix Scutellariae, Radix Platycodoniss, the Radix Paeoniae Alba, the Radix Stemonae, Pericarpium Citri Reticulatae, Radix Peucedani, Bombyx Batryticatus, Pi Rake leaf, Arisaema Cum Bile, Radix Asteriss, Bulbus Fritillariae Cirrhosae, Semen Benincasae, Semen Armeniacae Amarum, Indigo Naturaliss, Herba Schizonepetae, the Rhizoma Pinelliae, Herba Asari, Radix Glycyrrhizae, Herba Ephedrae, Rhizoma Imperatae, reed Root, Semen Persicae, Scolopendra, Pheretima crude drug are combined preparation, and these drug regimens are made each efficacy of drugs produce collaborative work With such that it is able to effectively treatment pertussis.Wherein it is because its nature and flavor bitter sweet from Folium Mori, tremble with fear, enter lung, Liver Channel, have wind-dispelling clear Heat, the function of cooling blood for improving eyesight, dispelling the wind and dampness pathogens generate heat, headache, conjunctival congestion, thirsty, cough due to lung-heat, migratory arthralgia, urticaria, lower limb elephatiasis.Choosing It is because its nature and flavor sweetness and bitterness with Flos Chrysanthemi, cool, enter lung, Liver Channel, have dispelling wind, disappear heat, improving eyesight, the function of removing toxic substances, control headache, dizziness, Conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.It is because that its nature and flavor is bitter from Fructus Forsythiae, cool, enter the heart, liver, gallbladder meridian, there is heat clearing away, removing toxic substances, dissipate Knot, the function of detumescence, control warm, erysipelas, macule, large carbuncle pyogenic infections, scrofula, urine leaching closes.It is because that its nature and flavor is bitter from Radix Scutellariae Cold, enter cardiopulmonary, gallbladder, large intestine channel, have removing the relative excess fire, except damp and hot, the function of arresting bleeding and miscarriage prevention, control high fever excessive thirst, cough due to lung-heat.From Fructus Citri tangerinae Stalk is because its nature and flavor toil, puts down, enters lung, stomach, have out lung qi dispersing gas, the function of eliminating the phlegm evacuation of pus, control exogenous cough, swelling throat Bitterly, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery is suffered from abdominal pain.It is because its nature and flavor picric acid, cool, enter liver, spleen channel from the Radix Paeoniae Alba, have blood-nourishing soft Liver, pain relieving in delaying, yin fluid astringing receives the function of antiperspirant, controls chest and abdomen pain over the hypochondriac region, diarrhea dysentery abdominal pain, spontaneous sweating, fever due to yin deficiency, menstruation is not Adjust, metrorrhagia, leukorrhagia.It is because its nature and flavor sweetness and bitterness, tepor from the Radix Stemonae, enters lung meridian have a gentle lung qi, cough-relieving, the function of parasite killing, Control cough due to wind and cold, pertussis, pulmonary tuberculosis, old cough with asthma, ascarid, enterobiasiss, skin scabies, eczema.It is because it from Pericarpium Citri Reticulatae Nature and flavor are bitter, pungent, temperature, and return lung, spleen channel have regulating qi-flowing for strengthening spleen, the function of drying dampness to eliminate phlegm, control fullness in the epigastrium and chest, lack of appetite and vomiting, expectorant of coughing Many.It is because that its nature and flavor is pungent, bitter from Radix Peucedani, is slightly cold that return lung warp has scattered wind heat clearing away, the function of lowering the adverse-rising QI to resolve phlegm, controls wind heat and cough Cough, abundant expectoration, expectorant dyspnea of heat type is full, cough up phlegm yellow thick.It is because that its nature and flavor is pungent, salty from Bombyx Batryticatus, put down, Return liver, lung meridian.Expelling wind to relieve convulsion, changes Expectorant eliminating stagnation.For apoplexy facial hemiparalysiss, twitch, head is grant, sore throat, scrofula tuberculosis, rubella erysipelas.It is because from Folium Eriobotryae Its nature and flavor is bitter, cool, attaches to the lung and stomach meridians, has lung heat clearing stomach function regulating, lowering the adverse-rising QI to resolve phlegm, controls lung-heat phlegmatic cough, hemoptysis, epistaxis, stomach energy is vomitted the sound of vomiting.From Arisaema Cum Bile is because that its nature and flavor is bitter, and cool in nature, enter the heart, liver, lung three warp have clearing away fire and eliminating phlegm, relieving convulsion fixed, phlegm-fire is breathed heavily and coughed, phlegm-accumulating vertigo. It is because that its nature and flavor is bitter from Radix Asteriss, temperature, enter lung meridian, have warming the lung, the therapeutic method to keep the adverse QI flowing downwards, expectorant, the function of antitussive, control cough due to wind and cold's asthma, Asthenia coughs vomiting bloody pus, sore throat, dysuria.It is because its nature and flavor bitter sweet from Bulbus Fritillariae Cirrhosae, cool, enter lung meridian, have lung moistening eliminating stagnation, only Cough the function of resolving sputum, control cough due to consumptive disease, spitting of blood of spitting, ambition pent-up, consumptive lung disease, lung abscess, goiter, scrofula, sore throat, acute mastitis.From Semen Benincasae is because that its nature and flavor is sweet, cool, enters meridian of Foot-JUE YIN, has lung moistening, resolving sputum, eliminating carbuncle, the function of diuretic, controls phlegm-heat cough, lung Carbuncle, acute appendicitis, gonorrhea, edema, tinea pedis, hemorrhoid, nasal surface wine.It is because that its nature and flavor is bitter from Semen Armeniacae Amarum, temperature, poisonous, enter lung, large intestine Warp, has expelling phlegm for arresting cough, relievings asthma, the function of intestine moistening, controls exogenous cough, dyspnea with fullness of the chest, sore throat, dry constipation of intestines.It is because it from Indigo Naturaliss Nature and flavor are salty, tremble with fear, and enter liver, lung, stomach have heat clearing away, removing heat from blood, the function of removing toxic substances, control epidemic febrile disease intenseness of heat, macule, spit blood, spit blood, children Frightened, sore swells, erysipelas, snake bite and insect sting.It is because that its nature and flavor is pungent from Herba Schizonepetae, temperature, enter lung, Liver Channel, deliver, wind-dispelling, treating blood disorderss Function, fries charcoal hemostasis, cure cold heating, headache, laryngopharynx swelling and pain, apoplexy locked mouth, spit blood, epistaxis, have blood in stool, metrorrhagia, puerperal blood Dizzy, carbuncle, sore scabies, scrofula.It is because that its nature and flavor is pungent from the Rhizoma Pinelliae, temperature, poisonous, enter spleen, stomach, have drying dampness to eliminate phlegm, sending down the abnormal ascending QI stops Vomit, the function of dissolving lump and resolving mass, control wet phlegm and cold drink, vomiting, regurgitation, cough and phlegm, fullness in chest, phlegm and headache, dizziness and sleepless, outward Subduing inflammation.It is because that its nature and flavor is pungent from Herba Asari, temperature, enter lung, kidney channel, have wind-dispelling, cold expelling, row water, open function surreptitiously, control air-cooled Headache, nasal sinusitis, pain relieving, phlegm retention cough with dyspnea, rheumatic arthralgia.Be because that its nature and flavor is sweet from Radix Glycyrrhizae, put down, enter spleen, stomach, lung meridian, have and Middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, process use, control weakness of the spleen and stomach, lack of appetite, loose stool of suffering from abdominal pain, overstrain generates heat, and consumptive lung disease is coughed Cough, cardiopalmus, shy；Raw use, controls laryngopharynx swelling and pain, peptic ulcer, ulcer sores, solution poison of drug and alimentary toxicosis.From Herba Ephedrae it is Because its nature and flavor is worked hard, temperature, enter lung, bladder warp, have diaphoresis, relieving asthma, the function of diuretic, control typhoid fever table in fact, fever with chills is lossless, Headache nasal obstruction, arthralgia, cough and asthma, edema due to wind pathogen edema, dysuria, ailment said due to cold or exposure insensitive impediment, munbness, rubella itch.From Rhizoma Imperatae is because that its nature and flavor is sweet, cold, enters lung, stomach, small intestine meridian, has removing heat from blood, hemostasis, heat clearing away, the function of diuresis, controls calentura and is tired of Yearningly, spit blood, epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.It is because its nature and flavor from Rhizoma Phragmitiss Sweet, tremble with fear, enter lung, stomach, have heat clearing away, promote the production of body fluid, relieving restlessness, the function of preventing or arresting vomiting, control pyreticosis polydipsia, gastropyretic vomiting, dysphagic, regurgitation, lung Flaccidity, lung abscess, and solve Fugu ocellatus ichthyotoxin.It is because its nature and flavor bitter sweet from Semen Persicae, put down, enter the heart, liver, large intestine channel, have blood stasis removing and clots absorbing, profit The function of dry cunning warp, controlling through closing, abdominal mass, calentura blood-retention, arthralgia due to stagnation of blood, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.From Wu Centipede is because that its nature and flavor is pungent, temperature, poisonous, enters Liver Channel, has wind-dispelling, arresting convulsion, counteracting toxic substances, and the function of eliminating stagnation controls apoplexy, shies, and breaks wound Wind, pertussis, scrofula, tuberculosis, buildup block, sore swollen toxin, tinea corporis, bald in vain, anal fistula, scald.It is because its property from Pheretima Salty in the mouth is trembled with fear, and Return liver spleen bladder warp has heat clearing away to walk frightened, dredging collateral, relievings asthma, the function of diuresis, for hyperpyrexia, coma, twitch, closes Section arthralgia pain, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.

Specific embodiment

The drug dose of instant component is also that inventor draws through groping in a large number to summarize, and the consumption of each component is following heavy All there is in the range of amount preferable curative effect：

8-10 gram of Folium Mori, 8-10 gram of Flos Chrysanthemi, 8-10 gram of Fructus Forsythiae, 8-10 gram of Radix Scutellariae, 8-10 gram of Radix Platycodoniss, 8-10 gram of the Radix Paeoniae Alba, Radix Stemonae 5-7 Gram, 4-8 gram of Pericarpium Citri Reticulatae, 4-8 gram of Radix Peucedani, 5-6 gram of Bombyx Batryticatus, 5-7 gram of Folium Eriobotryae, 5-7 gram of Arisaema Cum Bile, 5-7 gram of Radix Asteriss, 5-7 gram of Bulbus Fritillariae Cirrhosae, 5-7 gram of Semen Benincasae, 4-6 gram of Semen Armeniacae Amarum, Indigo Naturaliss 4-5 gram, 5-7 gram of Herba Schizonepetae, 5-7 gram of the Rhizoma Pinelliae, 2-3 gram of Herba Asari, 2-3 gram of Radix Glycyrrhizae, Herba Ephedrae 2-3 gram, 8-12 gram of Rhizoma Imperatae, 8-12 gram of Rhizoma Phragmitiss, 4-6 gram of Semen Persicae, 4-6 gram of Scolopendra, 7-9 gram of Pheretima.

It is preferably：

9 grams of Folium Mori, 9 grams of Flos Chrysanthemi, 9 grams of Fructus Forsythiae, 9 grams of Radix Scutellariae, 9 grams of Radix Platycodoniss, 9 grams of the Radix Paeoniae Alba, 6 grams of the Radix Stemonae, 6 grams of Pericarpium Citri Reticulatae, 6 grams of Radix Peucedani, 6 grams of Bombyx Batryticatus, 6 grams of Folium Eriobotryae, 6 grams of Arisaema Cum Bile, 6 grams of Radix Asteriss, 6 grams of Bulbus Fritillariae Cirrhosae, 6 grams of Semen Benincasae, 5 grams of Semen Armeniacae Amarum, 5 grams of Indigo Naturaliss, Herba Schizonepetae 6 Gram, 6 grams of the Rhizoma Pinelliae, 3 grams of Herba Asari, 3 grams of Radix Glycyrrhizae, 3 grams of Herba Ephedrae, 10 grams of Rhizoma Imperatae, 10 grams of Rhizoma Phragmitiss, 6 grams of Semen Persicae, 5 grams of Scolopendra, Pheretima 8 Gram.

The preparation method of medicine of the present invention is as follows

First, get the raw materials ready

1st, Folium Mori：Pick impurity, rub with the hands broken, winnow with a dustpan destemming, weed out spare；

2nd, Flos Chrysanthemi：Pick net leaf stalk, anthocaulus and spare impurity；

3rd, Fructus Forsythiae：Pick net impurity, stranding is opened, except discarding stalk；

4th, Radix Scutellariae：Pick impurity, remove residual stem, infiltrate or put slightly leaching in boiled water with cold water and pull out, section, dry；

5th, Radix Platycodoniss：Pick net impurity, except removing LU, clean and pull out, cut into slices after running through, dry；

6th, the Radix Paeoniae Alba：Pick impurity, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, moisten to inside and outside humidity uniformly, cut Piece, is dried；

7th, the Radix Stemonae：Pick net impurity, remove fibrous root, clean, run through rear cutting, dry；

8th, Pericarpium Citri Reticulatae：Take crude drug, remove the peel of impurity and blackening, wash quickly is net, softens, shredding, dries or cold drying, sieve Dedusting is considered to be worth doing；

9th, Radix Peucedani：Take crude drug, remove impurity, clean, run through, shave, be dried or cold drying, weed out chip；

10th, Bombyx Batryticatus：Take crude drug, remove residual silk, impurity；

11st, Folium Eriobotryae：Take Folium Eriobotryae cut tobacco, plus cooked Mel and certain amount of boiling water, mix thoroughly, slightly vexed, put the interior slow fire of pot and fry to not Till viscous handss, take out, cool, 100 jin of every Folium Eriobotryae cut tobacco, with 25 jin of cooked Mel；

12nd, Arisaema Cum Bile：Take crude drug, pick impurity；

13rd, Radix Asteriss：Pick impurity, remove residual stem, clean, slightly moistening, be cut into segment and dry；

14th, Bulbus Fritillariae Cirrhosae：Pick impurity, slightly steeped with water, pull out, moistening, peel off the heart, dry；

15th, Semen Benincasae：Pick net impurity, the used time smashs to pieces, or fried to yellow-white with slow fire, put at being dried；

16th, Semen Armeniacae Amarum：Pick net impurity, put in boiling water and slightly boil, skin microcreping of waiting rises to be pulled out, in leaching cold water, slough kind of a skin, dry, winnow with a dustpan net；

17th, Indigo Naturaliss：Pick impurity, cross square-bottomed bamboo basket；

18th, Herba Schizonepetae：Pick net impurity, slightly steeped with water, pull cutting out, dry；

19th, the Rhizoma Pinelliae：Pick impurity, weed out ash bits；

20th, Herba Asari：Cleared impurity, sprays profit, timely cutting with water, dries；

21st, Radix Glycyrrhizae：It is a little that extracting liquorice piece adds cooked Mel and boiled water, mixes thoroughly, slightly vexed, puts the interior slow fire of pot and fries to being changed into deep yellow Color, tack-free till, taking-up cools, and 100 jin of every Radix Glycyrrhizae, with refined honey 25-30 jin；

22nd, Herba Ephedrae：Pick impurity, remove most woody stems and undesirable root, wash, cutting after micro- profit, it is drying to obtain；

23rd, Rhizoma Imperatae：Pick net impurity, clean, micro- profit, cutting, dry, net chip of winnowing with a dustpan；

24th, Rhizoma Phragmitiss：Pick impurity and root, cutting, dry；

25th, Semen Persicae：Remove duricrust impurity, put in boiling water pot and boil to crust microcreping, pull out, in immersion cold water, rub with the hands and remove kind of a skin, shine Dry, winnow with a dustpan net；

26th, Scolopendra：Wipe net, remove cephalopodium, cut off use；

27th, Pheretima：Take crude drug, remove impurity, clean, essence profit, cutting, it is dried.

2nd, prepare

1st, by the Folium Mori after processing, Flos Chrysanthemi, Fructus Forsythiae, Radix Scutellariae, Radix Platycodoniss, the Radix Paeoniae Alba, the Radix Stemonae, Pericarpium Citri Reticulatae, Radix Peucedani, Bombyx Batryticatus, Folium Eriobotryae, gallbladder south Star, Radix Asteriss, Bulbus Fritillariae Cirrhosae, Semen Benincasae, Semen Armeniacae Amarum, Indigo Naturaliss, Herba Schizonepetae, the Rhizoma Pinelliae, Herba Asari, Radix Glycyrrhizae, Herba Ephedrae, Rhizoma Imperatae, Rhizoma Phragmitiss, Semen Persicae, Wu Centipede, Pheretima medicine are put in decocting container, and add water 8 times amount for the first time, after soaking 60 minutes, fry by intense fire to boil and rise, then use slow fire Decoct 30 minutes, filter to obtain first time decoction liquor, first time decoction liquor is poured in container；

2nd, the medicinal residues of filtration are added water 6 times amount, boil by intense fire, then filtered with boiling 20 minutes by slow fire, second decoction liquor is fallen Enter in container；

3rd, will decoction liquor mixing and stirring twice, obtain final product admixing medical solutions, be divided into 4 doses and take.

In prescription, the Radix Stemonae has gentle lung qi, cough-relieving, and the function of parasite killing is monarch drug；Radix Platycodoniss open lung qi dispersing gas, eliminating the phlegm evacuation of pus, Radix Peucedani Scattered wind heat clearing away, both lowering the adverse-rising QI to resolve phlegm are ministerial drug, and three taste medicines play clearing heat and moistening lung, relieving cough and resolving phlegm, the effect of dehumidifying sending down the abnormal ascending QI jointly, control Treat pertussis effect comprehensively, and with clearing heat and moistening lung, based on relieving cough and resolving phlegm, can effect a permanent cure；Bulbus Fritillariae Cirrhosae lung moistening eliminating stagnation, antitussive resolving sputum is assistant Medicine；Semen Armeniacae Amarum expelling phlegm for arresting cough, relievings asthma, and intestine moistening is to make medicine, and all medicines are to take stopgap measures with being left.

Medicine of the present invention has clearing heat and moistening lung, eliminating dampness dissolving phlegm, the function of relieving cough and asthma, for treating pertussis, short treating period, Instant effect, non-relapse after healing, have no toxic side effect.

The beneficial effect of of the present invention medicine is expanded on further below by way of test example, these test examples include this The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.

The animal toxicity test report of [test example 1] medicine of the present invention：

Take rabbit 30, male and female dual-purpose, body weight 2.0 2.5kg, divide two groups, every group 15, one of which is that overdose is tested Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is given for administration by gavage Medicine, twice daily, serve on 7 days, and daily observation is administered reaction, and result shows that two groups of rabbit activities, diet are normal, and medicine is no bad Toxic and side effects.

The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention

1st, physical data

Accept pertussis out-patient totally 40 for medical treatment.

2nd, diagnostic criteria

Have in 1～2 week before onset and pertussis infant contact history, child is common.Morbidity is more slow, and disease just has low grade fever and flu disease Shape, cough gradually increases, and night is play, a succession of paroxysmal spasmodic cough of paroxysmal and with inspiratory croup after 1 week, recurrent exerbation, Though the cough many absence of signs of pulmonary again.

Leukocyte showed increased, Chang Da（30～50）× 10 [9]/L, lymphocyte up to more than 0.50～0.70.

3rd, Therapeutic Method

From above-mentioned medicament, take to patient, 2 times a day, each take 1 dose, early daily, evening respectively takes 1 time, be within 7 days a treatment Journey, continuously takes the 2-3 course for the treatment of.

4th, efficacy assessment standard

Effective：Pertussis symptom disappears, recovery from illness, and body constitution recovers normal；

Take a turn for the better：Pertussis symptom is clearly better, and flu, heating paresthesia eliminate, and body constitution is progressively recovered；

Invalid：Do not reach improvement standard person.

5th, therapeutic outcome（See table）

In above-mentioned treatment, with Drug therapy pertussis patient of the present invention 40, effective 36 of result, obvious effective rate is 90%, takes a turn for the better 2, improvement rate is 5%, invalid 2, and total effective rate is 95%.

Claims

1. one kind treat pertussal medicine it is characterised in that：It is made up of the crude drug in following amount ranges：

2. medicine according to claim 1, the consumption of wherein each crude drug is：

3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps：

（One）Get the raw materials ready

（1）Folium Mori：Pick impurity, rub with the hands broken, winnow with a dustpan destemming, weed out spare；

（2）Flos Chrysanthemi：Pick net leaf stalk, anthocaulus and spare impurity；

（3）Fructus Forsythiae：Pick net impurity, stranding is opened, except discarding stalk；

（4）Radix Scutellariae：Pick impurity, remove residual stem, infiltrate or put slightly leaching in boiled water with cold water and pull out, section, dry；

（5）Radix Platycodoniss：Pick net impurity, except removing LU, clean and pull out, cut into slices after running through, dry；

（6）The Radix Paeoniae Alba：Pick impurity, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, moisten to inside and outside humidity uniformly, Section, is dried；

（7）The Radix Stemonae：Pick net impurity, remove fibrous root, clean, run through rear cutting, dry；

（8）Pericarpium Citri Reticulatae：Take crude drug, remove the peel of impurity and blackening, wash quickly is net, softens, shredding, dries or cold drying, Weed out ash bits；

（9）Radix Peucedani：Take crude drug, remove impurity, clean, run through, shave, be dried or cold drying, weed out chip；

（10）Bombyx Batryticatus：Take crude drug, remove residual silk, impurity；

（11）Folium Eriobotryae：Take Folium Eriobotryae cut tobacco, plus cooked Mel and certain amount of boiling water, mix thoroughly, slightly vexed, put the interior slow fire of pot and fry to not Till viscous handss, take out, cool, 100 jin of every Folium Eriobotryae cut tobacco, with 25 jin of cooked Mel；

（12）Arisaema Cum Bile：Take crude drug, pick impurity；

（13）Radix Asteriss：Pick impurity, remove residual stem, clean, slightly moistening, be cut into segment and dry；

（14）Bulbus Fritillariae Cirrhosae：Pick impurity, slightly steeped with water, pull out, moistening, peel off the heart, dry；

（15）Semen Benincasae：Pick net impurity, the used time smashs to pieces, or fried to yellow-white with slow fire, put at being dried；

（16）Semen Armeniacae Amarum：Pick net impurity, put in boiling water and slightly boil, skin microcreping of waiting rises to be pulled out, in leaching cold water, slough kind of a skin, dry, winnow with a dustpan Only；

（17）Indigo Naturaliss：Pick impurity, cross square-bottomed bamboo basket；

（18）Herba Schizonepetae：Pick net impurity, slightly steeped with water, pull cutting out, dry；

（19）The Rhizoma Pinelliae：Pick impurity, weed out ash bits；

（20）Herba Asari：Cleared impurity, sprays profit, timely cutting with water, dries；

（21）Radix Glycyrrhizae：It is a little that extracting liquorice piece adds cooked Mel and boiled water, mixes thoroughly, slightly vexed, puts the interior slow fire of pot and fries to being changed into deep yellow Color, tack-free till, taking-up cools, and 100 jin of every Radix Glycyrrhizae, with refined honey 25-30 jin；

（22）Herba Ephedrae：Pick impurity, remove most woody stems and undesirable root, wash, cutting after micro- profit, it is drying to obtain；

（23）Rhizoma Imperatae：Pick net impurity, clean, micro- profit, cutting, dry, net chip of winnowing with a dustpan；

（24）Rhizoma Phragmitiss：Pick impurity and root, cutting, dry；

（25）Semen Persicae：Remove duricrust impurity, put in boiling water pot and boil to crust microcreping, pull out, in immersion cold water, rub with the hands and remove kind of a skin, shine Dry, winnow with a dustpan net；

（26）Scolopendra：Wipe net, remove cephalopodium, cut off use；

（27）Pheretima：Take crude drug, remove impurity, clean, essence profit, cutting, it is dried；

（Two）Preparation

（1）By the Folium Mori after processing, Flos Chrysanthemi, Fructus Forsythiae, Radix Scutellariae, Radix Platycodoniss, the Radix Paeoniae Alba, the Radix Stemonae, Pericarpium Citri Reticulatae, Radix Peucedani, Bombyx Batryticatus, Folium Eriobotryae, gallbladder Rhizoma Arisaematis, Radix Asteriss, Bulbus Fritillariae Cirrhosae, Semen Benincasae, Semen Armeniacae Amarum, Indigo Naturaliss, Herba Schizonepetae, the Rhizoma Pinelliae, Herba Asari, Radix Glycyrrhizae, Herba Ephedrae, Rhizoma Imperatae, Rhizoma Phragmitiss, Semen Persicae, Scolopendra, Pheretima medicine are put in decocting container, and add water 8 times amount for the first time, after soaking 60 minutes, fry by intense fire to boil and rise, then with civilian Fire decocts 30 minutes, filters to obtain first time decoction liquor, first time decoction liquor is poured in container；

（2）The medicinal residues of filtration are added water 6 times amount, boils by intense fire, then filtered with boiling 20 minutes by slow fire, second decoction liquor is fallen Enter in container；

（3）To decoction liquor mixing and stirring twice, obtain final product admixing medical solutions, be divided into 4 doses and take.