CN106389136A - 植物纳米乳痤疮膏 - Google Patents
植物纳米乳痤疮膏 Download PDFInfo
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- CN106389136A CN106389136A CN201610719123.XA CN201610719123A CN106389136A CN 106389136 A CN106389136 A CN 106389136A CN 201610719123 A CN201610719123 A CN 201610719123A CN 106389136 A CN106389136 A CN 106389136A
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- acne
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/068—Microemulsions
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- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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Abstract
本发明公开了一种植物纳米乳痤疮膏,是属于现代中药化妆品痤疮纳米乳膏配置生产科学领域。天然植物玉竹当归抑菌消炎止痒,仙人掌白芍清热解毒活血消肿,金银花连翘清痘嫩肤,藏红花薏仁祛斑祛痘抗氧化,黄柏黄芩活血行血解毒疗疮纳米乳痤疮膏组成。由于纳米乳化天然植物药中有效营养疗效活性成分全部得以保留,渗透吸收好,比表面积广,抗真菌,病毒,细菌及皮质激素的有效成分,联合共用,药物治标又治本,从根本上去除妊娠纹,蝴蝶斑,黄褐斑,老人斑,雀斑;青春痘即痤疮,粉刺,治愈率高,调节免疫,促进细胞***增殖,提高肌肤抵抗力,使肌肤增白,细腻光滑,消斑除皱等多种作用。
Description
技术领域:
本发明公开了一种植物纳米乳痤疮膏,是属于现代中药化妆品痤疮膏配制生产技术领域。
背景技术:
痤疮,又称寻常型痤疮,是***常见的皮肤病,其特点是颜面及胸背散在发生针尖或米粒大小的皮疹,火箭黑头,能挤出粉渣样物,俗称“粉刺”。多见于青年男女。
现代医学认为,痤疮是毛囊皮脂腺的慢性炎症,是一种多因素疾病。至今,其发病机制尚未完全明了。皮脂的瘀积,毛囊内细菌、螨虫等微生物感染,内分泌因素,是痤疮发病的主要因素。雄性激素在错长的发病过程中起着总要的支配作用。此外,痤疮的发病,与过食甜食、便秘、精神紧张、遗传因素、锌缺乏、气候闷热潮湿、使用化妆品以及使用某些药物如碘化物、溴化物、卤化物、肾上腺皮脂激素、、苯妥英钠、异烟肼等有关。痤疮多发于面颊、前额,亦可见胸背。初起皮疹为芝麻到绿豆大小,与肤色形同或红色,顶端日渐呈现黑头。可挤压出黄色粉渣,易遗留凹陷瘢痕。皮疹散在分布,部分患者皮疹扩大黄豆或蚕豆大小,呈暗红色,消退后成瘢痕疙瘩。
西医治疗本病主要是去除病因,寻常痤疮只要不乱挤压,不乱用药,积极治疗,一般愈后较好。结节型、囊肿型、混合型愈后欠佳,治疗比较棘手,因而对此类患者应尽早采取积极正确的治疗方法,防止瘢痕形成,影响容貌美观。
中医学称之为“肺风粉刺”、“面粉渣”、“酒刺”、“嗣面”、“风刺”等。认为肌体血热偏盛是痤疮发病的根本;饮食不节,外邪侵袭是致病的条件;血瘀痰结使病情复杂深重。若肺经风热者,治以清肺散热;湿热蕴结者,治以清热化湿通肺;痰湿凝结者,治以消痰软坚,活血化瘀。通过辩证施治,以清除血热偏盛、肺胃积热、外感风热、气血凝塞、血瘀痰结等病理因素,达到预期的疗效。
发明内容
本发明的目的在于提供一种植物纳米乳痤疮膏。
本发明的技术解决方案是
1、一种植物纳米乳痤疮膏,其特征是:所述天然植物玉竹当归抑菌消炎止痒纳米乳痤疮膏,按下列质量分配比组成%
其中玉竹当归混合液提取物按下列质量份配比组成%
②制作方法 将甲组原料和乙组原料甘油、玉竹、当归混合液等提取物制成粒径在30~100nm的天然植物纳米乳及水分别加热至75℃。在此温度下,边搅拌边将一组徐徐加入甲组进行乳化,当温度降至45℃以下时加入柠檬油、防腐剂,搅拌均匀,静置冷却后回装。其中玉竹当归的纳米乳制备方法,将白介素、蜂蜜、蓖麻油以外的其余药物粉碎成60目的粗粉,加入8倍的水,制成混悬液,在胶体磨中混匀进行细化处理,细化液再置于均质机中进行混匀细化,进行纳米化粉碎,制成粒径30~100nm的天然营养材料纳米化液,搅拌均匀,然后加入白介素、蜂蜜和蓖麻油,调成膏状即为成品。
③应用 本品即可营养皮肤,又可以保湿、抑菌、养颜、美容、抗衰老,还能软化皮肤,消炎止痒。本品中含有的天然植物药具有解毒消炎、托疮生肌功效,能够疏通皮脂腺导管,加快创口愈合。
白介素是人体中一种具有重要免疫调节功能的淋巴因子,具有促进皮肤细胞分化增殖的作用,可以提高皮肤的抵抗力,消退色素,使肌肤出现生理性增白,细腻光滑,减少复发。本品可迅速消除粉刺、痤疮,并具有嫩肤、抗皱、保健作用。
使用方法:粉刺痤疮患者每晚使用本品1次,并在脸上保留8h以上。同时禁食腥、辣、蛋、酒,每天坚持按摩三阴交穴、足三里穴、合谷穴和血海穴3~5min,以有酸麻胀痛感为好。
本品配方合理,工艺简单,使用方便,抛开口服药的传统疗法,以外配合穴位按摩,效果显著,且对人体无不良影响。
2、一种植物的纳米乳痤疮膏,其特征是:所述天然植物仙人掌白芍清热解毒活血消肿纳米乳痤疮膏,按下列质量分配比组成%
制备方法
将天然的仙人掌、白芍、甘草苷、寒石粉、樟脑粉、冰片粉,材料粉碎成60目的粗粉,加入8倍的水,制成混悬液,在胶体磨中混匀进行细化处理,细化液再置于均质机中进行混匀细化,进行纳米化粉碎,制成粒径30~100nm的天然植物仙人掌白芍等纳米化乳和制作化妆品的辅料组成的。
具体方法是(1)将上述各原料按水相、油相分别放入两只不锈钢搅拌缸中,分别加热80-95℃,然后将水相物倒入油相,再继续搅拌1min。
(2)将物料边搅拌冷却至45-50℃左右时加香精,继而再缓缓搅拌待温度冷却至35℃左右时停止搅拌放入消毒净化车间分装保存。
仙人掌萃取物含有多种生理活化成分,配以白芍萃取物、甘草苷,对多种病菌如许兰氏毛菌、红色表皮癣菌等都有很强的抑制作用;白芍萃取物具有抗菌消炎与抗溃疡作用;甘草苷为抗炎剂,具有抑菌作用;角鲨烷为皮肤润滑剂;尼泊金甲酯为防腐剂。
寒石外用有柔润肌肤、扩张血管、治疗皮炎的作用;樟脑外用有镇痛止痒作用;冰片对感觉神经有轻微的刺激作用,有温和的止痛止痒作用;凡士林作为基质药物有润滑、防止皮肤皲裂作用,含少量水,易吸收。
本品对细菌病菌有抑制作用,具有清热解毒、活血消肿的功效。主要用于治疗粉刺、痤疮,对雀斑、黄褐斑、妊娠斑也有明显疗效。
使用方法:洗完脸后将本品涂抹于脸部患处,像涂抹雪花膏一样,使患处保持一层油膜。每天使用1~2次。
3、一种植物纳米乳痤疮膏,其特征是:所述天然植物金银花连翘清痘嫩肤纳米乳痤疮膏,按下列质量分配比组成%
制备方法 按上述用料称取方药组药物35份,加冷水350份,冷浸15min,煮沸1h后用100目筛滤过;药渣再加入280份冷水煮沸30min后密封,恒温80℃温浸4h后100目筛滤过(在煮沸和温浸的过程中不要乱搅动);药渣压榨出残余药汁后用100目筛滤过;3次滤液混合在60~70℃之间低温浓缩至1∶1(质量比,即1份浓缩药汁相当于1份原药材)后,得浓缩药汁35份,在胶体磨中混匀进行细化处理,细化液再置于均质机中进行混匀细化,进行纳米化份碎,制成粒径在30~100nm的天然营养材料纳米化液。加入软膏基质64份中搅匀,再加入芳香剂组樟脑细末1份搅匀,即制成100份浅棕色的清痘嫩肤膏。本品治疗痤疮有效率,治愈率高,不复发,且本品中含有抗毒素、抗真菌、抗细菌及皮质激素的有效成分,联合用药。对痤疮及引起的感染有综合治疗作用;本品见效快,使皮肤恢复润泽,不留痕迹。
4、一种天然自我纳米乳痤疮膏,其特征是:所述天然植物藏红花薏仁祛斑祛痘抗氧化纳米乳痤疮膏,按下列质量分配比组成%
制备方法 将所述的藏红花、双花、连翘、大青叶、板蓝根、薏仁、桔梗、功劳叶、黄芩、棱霄花和甘草、柿子叶、珍珠粉研磨成粒径在30~100nm的纳米化微乳,这种纳米化产品保持了天然营养材料的全部营养成分,所以化妆品痤疮膏中的营养成分和功效更齐全。这种化妆品痤疮膏具有良好的渗透性能,渗透速度较快,吸收效果较好。将蜂蜜加热至50~105℃,然后将所述的浸泡到所述蜂蜜中,常温浸泡50~60d即可。
本品是一种天然抗氧化剂,可提高人体的生理机能,可促进细胞的新陈代谢,并且具有抗菌消炎,是一种治疗粉刺、痤疮的清痘嫩肤膏。药物治标又治本,从根本上消除妊娠纹、蝴蝶斑、黄褐斑、老年斑、雀斑、青春痘(痤疮)和粉刺。
5、一种植物纳米乳痤疮膏,其特征是:所述天然植物黄柏黄芩活血行血解毒疗疮纳米乳痤疮膏,按下列质量分配比组成%
制备方法 将以上各原料去杂除尘,清洗后粉碎,用胶体磨研磨,制成粒径在30~100nm的纳米级粉碎物或纳米化微乳,这种纳米化产品保持了天然营养材料的全部营养成分,所以化妆品中的营养成分更齐全。这种化妆品具有良好的渗透性能,渗透速度较快,吸收效果好。
中药原料中有活血行血、消热解毒、祛火消肿,调节皮肤内环境的营养功效活性成分。西药利菌沙抑制并杀灭粉刺局部棒状杆菌,抑制细菌内脂肪酸酶的合成及其活性,防治甘油三酸酯水解成游离脂肪酸,避免毛囊受到破坏,避免毛囊炎的产生。
黄柏具有清热燥湿、解毒疗疮功能;黄芩具有清热燥湿、泻火解毒、止血、安胎功能;大黄具有泄热通肠、凉血解毒、逐瘀通经功能;泽兰具有活血化瘀、行水消肿功能;珍珠具有镇心安神、养阴熄风、清热祛痰、去翳明目、解毒生肌功能;芙蓉叶具有清肺凉血、消肿排脓功能;红粉具有拔毒、除脓、去腐生肌功能;轻粉外用杀虫、攻毒、敛疮,内服祛痰消积、逐水通便;麝香具有开窍醒神、活血通经、止痛等功能;硼砂具有清热消痰、解读防腐功能;芝麻油具有润燥、解毒、消肿、止痛功能。
本品具有祛斑生肌、脱脂消炎、活血化瘀等功效,可用于治疗粉刺、痤疮、雀斑、黄褐斑、色素沉着、酒糟鼻、痤疮留下的红印、黑斑及各种皮炎。具有调节皮脂腺分泌,保持皮脂腺导管通常、回复正常代谢的功效,可以在对面部皮肤粉刺进行治疗的同时,对局部皮肤进行嫩肤保养护理作用。
使用方法:每晚用药1次,擦于患处,保持10h。
本品成本低,工艺便于实施;采用天然植物药配方,纳米技术提取,配比科学,使用方便,效果显著,对人体无毒副作用。
下面结合实施例子对本发明进一步阐明:
具体实施方法:
实施例1、一种植物纳米乳痤疮膏,其特征是:所述天然植物玉竹当归抑菌消炎止痒纳米乳痤疮膏,按下列质量分配比组成%
其中玉竹当归混合液提取物按下列质量份配比组成%
实施例2、一种植物的纳米乳痤疮膏,其特征是:所述天然植物仙人掌白芍清热解毒活血消肿纳米乳痤疮膏,按下列质量分配比组成%
实施例3、一种植物纳米乳痤疮膏,其特征是:所述天然植物金银花连翘清痘嫩肤纳米乳痤疮膏,按下列质量分配比组成%
实施例4、一种天然自我纳米乳痤疮膏,其特征是:所述天然植物藏红花薏仁祛斑祛痘抗氧化纳米乳痤疮膏,按下列质量分配比组成%
实施例5、一种植物纳米乳痤疮膏,其特征是:所述天然植物黄柏黄芩活血行血解毒疗疮纳米乳痤疮膏,按下列质量分配比组成%
Claims (5)
1.一种植物纳米乳痤疮膏,其特征是:所述天然植物玉竹当归抑菌消炎止痒纳米乳痤疮膏,按下列质量分配比组成%
其中玉竹当归混合液提取物按下列质量份配比组成%
2.一种植物的纳米乳痤疮膏,其特征是:所述天然植物仙人掌白芍清热解毒活血消肿纳米乳痤疮膏,按下列质量分配比组成%
3.一种植物纳米乳痤疮膏,其特征是:所述天然植物金银花连翘清痘嫩肤纳米乳痤疮膏,按下列质量分配比组成%
4.一种天然自我纳米乳痤疮膏,其特征是:所述天然植物藏红花薏仁祛斑祛痘抗氧化纳米乳痤疮膏,按下列质量分配比组成%
5.一种植物纳米乳痤疮膏,其特征是:所述天然植物黄柏黄芩活血行血解毒疗疮纳米乳痤疮膏,按下列质量分配比组成%
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CN113101341A (zh) * | 2021-03-25 | 2021-07-13 | 中国工程物理研究院材料研究所 | 黄精在制备防治低剂量或/和慢性铀暴露药物中的应用 |
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