CN106362111A - Pharmaceutical composition for improving phlegm-dampness constitution, medicine brick and preparation method of medicine brick - Google Patents
Pharmaceutical composition for improving phlegm-dampness constitution, medicine brick and preparation method of medicine brick Download PDFInfo
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- CN106362111A CN106362111A CN201610772516.7A CN201610772516A CN106362111A CN 106362111 A CN106362111 A CN 106362111A CN 201610772516 A CN201610772516 A CN 201610772516A CN 106362111 A CN106362111 A CN 106362111A
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- A61K36/88—Liliopsida (monocotyledons)
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Abstract
The invention provides a pharmaceutical composition for improving phlegm-dampness constitution. The composition comprises the following components in parts by weight: 60 to 100 parts of rhizoma pinelliae, 180 to 220 parts of pericarpium citri reticulatae, 130 to 170 parts of poria cocos, 10 to 50 parts of prepared liquorice root, 40 to 80 parts of fructus mume, 100 to 140 parts of rhizoma zingiberis recens, 60 to 100 parts of fructus perillae, 60 to 100 parts of semen raphani, 40 to 80 parts of semen brassicae, 10 to 50 parts of alismatis rhizome, 40 to 80 parts of bambusae caulis in taenias, 60 to 100 parts of fructus aurantii immaturus, 80 to 120 parts of bighead atractylodes rhizome, 60 to 100 parts of radix aucklandiae, 10 to 50 parts of semen arecae, 40 to 80 parts of radix codonopsis, 60 to 100 parts of semen lablab album, 100 to 140 parts of semen coicis, 80 to 120 parts of rhiizoma dioscoreae, 40 to 80 parts of lotus seed flesh, 10 to 50 parts of fructus amomi, 40 to 80 parts of fossil fragments and 60 to 100 parts of concha ostreae. The invention further provides a medicine brick prepared by using the composition, and a preparation method thereof.
Description
Technical field
The present invention relates to the field of Chinese medicines, in particular to a kind of pharmaceutical composition improving phlegm-dampness constitution and a kind of medicine
Brick and preparation method thereof.
Background technology
Phlegm-dampness constitution is exactly the pathologic basis having the not smooth undertone of blood operation or blood-stasis internal-depression in vivo, with phlegm-damp table
It is now the constitution status of principal character.
" Further Discourses on the Properties of Things " has " fertile people's excessive phlegm ", " fertile people is wet many ", and " the red small stream method for the treatment of heart will " has " fertile white man many phlegm-damp ", phlegm-damp
The body characteristicses of body constitution can be summarized as following five aspects.Body characteristicses: obesity, abdominal part grossness is soft.Psychological peculiarity: property
Lattice partial temperature and, steady respectful modest, and reach, be good at restraining oneself more.Common manifestation: major event: skin of face oils and fatss are more, hyperhidrosis and glutinous, breast
Vexed, abundant expectoration.Secondary item: complexion general edema with yellowish tinge of the skin and dim, eye born of the same parents are micro- floating, easily sleepy, and corpulent tongue is big usually, white and greasy fur, sticky and greasy in mouth or sweet,
Heavy sensation of the body is not well, rolling pulse, preference for fat and sweet food, and stool is normal or unreal, and urine is few or micro- mixed.Adaptive capacity to environment to external world: to prunus mume (sieb.) sieb.et zucc.
Rainy season and wet environment adaptability are poor, are susceptible to suffer from damp syndrome.Morbidity tendency: be susceptible to suffer from quenching one's thirst, the disease such as apoplexy, thoracic obstruction.
Phlegm-damp is treated by topical agent, adopts herbal fomentation therapy more, using hot towel, hot water bag or have heating
The therapeutic equipmentss of effect, by middle drug application in people's body surface, by the dual function of medicine and hot compress, to alleviate, to treat cold body constitution.
Herbal fomentation therapy is exactly the physiological property using skin, so that medicine is turned by skin surface absorption, stratum corneum penetration and corium
Transport and play pharmacodynamics effect into blood circulation.Herbal fomentation has concentrated traditional Chinese medical science medication, thermotherapy, tcm herbal ion osmotic therapeutic therapy
Deng several functions, melt temperature, humidity, drug level in one, because disease treats, medicine is suited the medicine to the illness, can the multiple disease of effectively treatment.Directly
Connect and Chinese medicine is heated, eliminate that traditional needs and first decocting for Chinese herbal medicine is become liquid cumbersome process, by by a steady stream not
Disconnected medicine of a warm nature molecule directly acts on human body, expansion blood vessel locally and systemically in the way of convection current and infiltration, promotes body surface group
The blood circulation knitted, improves the Absorption of skin, promotes a large amount of secretions of sweat gland, accelerates the metabolism of skin;Simultaneously by
In fomentation medicine effusion Chinese medicine particle (for molecule or ion) act on body surface directly produce acaricide, parasite killing, sterilization, antiinflammatory,
Antipruritic, control pain etc. effect, or transdermal absorb human body by excite histiocyte receptor Biochemical processes play medication make
With, and then eliminate focus.
But, the herbal fomentation therapy in correlation technique, because Chinese medicine needs the dermal contact with patient, and also need to
Medical personnel or patient hand-held towel, hot water bag or the therapeutic equipmentss with heat effect, to the position being covered with Chinese medicine
Heating, so, it is not easy to medical personnel or patient's operation.It is therefore desirable to have new hot compress therapy is solving the above problems.
Report in prior art and be used health-preserving heated brick bed as medical apparatus and instruments, the medicine group of medicine brick is made in heating in heated kang
Compound, when being administered in this way, the medicine brick after heating can discharge Chinese medicine particle (for molecule or ion), thus inhaling through transdermal
Take in human body, excite the effect of the Biochemical processes volatilization medication of histiocyte receptor, and then reach treatment affected part
Purpose.This way it is not necessary to medical personnel or the hand-held firing equipment of patient are carried out to the affected part of patient.
However, due to being conventionally used for herbal fomentation therapy with difference by the way of health-preserving heated brick bed heating medicine brick administration very
Greatly, in order to adapt to different administering modes, need one kind can prepare patent medicine brick, and be well adapted for heating to be administered this administration
The compositionss of mode, it also needs to have good drug effect concurrently simultaneously.
In view of this, the present invention is proposed.
Content of the invention
The first object of the present invention is to provide a kind of pharmaceutical composition improving phlegm-dampness constitution, described pharmaceutical composition
Phlegm-dampness constitution can effectively be improved, and especially adapt to the administering mode of heating topical administration;
The second object of the present invention is to provide a kind of medicine brick, and described medicine brick mixes system by described pharmaceutical composition with loess
Standby, well pharmaceutically active substance can be discharged by heating, reach therapeutic effect;
The third object of the present invention is to provide the preparation method of described medicine brick, methods described process clearly it is easy to
Control, favorable reproducibility.
In order to realize the above-mentioned purpose of the present invention, spy employs the following technical solutions:
One aspect of the present invention is related to a kind of pharmaceutical composition improving phlegm-dampness constitution, and described compositionss are included by weight
The following components of part meter:
Rhizoma Pinelliae Preparatum 60-100 part, Pericarpium Citri Reticulatae 180-220 part, Poria 130-170 part, Radix Glycyrrhizae Preparata 10-50 part, Fructus Mume 40-80 part,
Rhizoma Zingiberis Recenss 100-140 part, Fructus Perillae 60-100 part, Semen Raphani 60-100 part, Semen Sinapis Albae 40-80 part, Rhizoma Alismatis 10-50 part, Caulis Bambusae In Taenia 40-80
Part, Fructus Aurantii Immaturus 60-100 part, Rhizoma Atractylodis Macrocephalae 80-120 part, Radix Aucklandiae 60-100 part, Semen Arecae 10-50 part, Radix Codonopsis 40-80 part, Semen Lablab Album 60-
100 parts, Semen Coiciss 100-140 part, Rhizoma dioscoreae 80-120 part, Semen Nelumbinis 40-80 part, Fructus Amomi 10-50 part, Os Draconis 40-80 part, male
Oyster 60-100 part.
Rhizoma Pinelliae Preparatum, Pericarpium Citri Reticulatae, Poria, Radix Glycyrrhizae Preparata, Fructus Mume, Rhizoma Zingiberis Recenss have compatibility effect, can have as expectorant during combination
Drying dampness to eliminate phlegm, qi-regulating and middle the effect of.Cure mainly dampness-phlegm syndrome.Cough with copious phlegm, Se Baiyi coughs up, nausea and vomiting, and chest and diaphragm painful abdominal mass is vexed, and limbs are stranded
Weight, or vertigo and palpitation, white and slippery fur or greasy, rolling pulse.Clinic be usually used in treat chronic bronchitiss, chronic gastritiss, Meniere,
Nervous vomiting etc. belongs to damp-phlegm person.
Fructus Perillae, Semen Sinapis Albae, Semen Raphani have compatibility effect, have warming the lung for resolving phlegm during combination, the effect of sending down the abnormal ascending QI helps digestion.Cure mainly
Phlegm stops up the circulation of vital energy in the wrong direction dyspepsia is demonstrate,proved.Cough dyspnea, the abundant expectoration feeling of stuffiness in chest, lack of appetite difficulty disappears, white and greasy fur, rolling pulse.Clinic is usually used in treating intractable
The phlegm stops up the circulation of vital energy in the wrong direction dyspepsia person such as cough, chronic bronchitiss, bronchial asthma, pulmonary heart disease.
The Rhizoma Atractylodis Macrocephalae, Rhizoma Alismatis, Pericarpium Citri Reticulatae (going white), the Radix Aucklandiae, Semen Arecae, Poria have compatibility effect, can be used for expectorant disease and turn to during combination
Aqueous vapor, change of disease ascites are it is impossible to eat.
WEIDANTANG, has compatibility effect by the Rhizoma Pinelliae, Caulis Bambusae In Taenia, Fructus Aurantii Immaturus, Pericarpium Citri Reticulatae, Radix Glycyrrhizae, Poria, can be used as eliminating the phlegm during combination
Agent, has the effect of activating QI to eliminate phlegm, stomach function regulating function of gallbladder promoting.Cure mainly syndrome of stagnated gallbladder qi with disturbing phlegm.Timid easily frightened, vertigo and palpitation, dysphoria and insomnia, night is many
Different dream;Or vomiting and nausea singultuss, dizziness, epilepsy.Tongue is greasy in vain, stringy and rolling pulse.Clinic be usually used in treat neurosiss, acute or chronic gastritis,
Peptic ulcer, chronic bronchitiss, Meniere, climacteric syndrome, epilepsy etc. belong to stagnation of the gallbladder-QI and disturbance of phlegm person.
Semen Lablab Album, the Rhizoma Atractylodis Macrocephalae, Poria, Radix Glycyrrhizae, Radix Platycodoniss, Semen Nelumbinis, Radix Ginseng, Fructus Amomi, Rhizoma Dioscoreae, Semen Coiciss composition.Tonifying the spleen and stomach, lung benefiting
Gas has compatibility effect, can be used for weakness of the spleen and stomach, anorexia and loose stool, shortness of breath is coughed, lassitude of the limbs and weakness during combination.
Preferably, described compositionss include following components by weight:
Rhizoma Pinelliae Preparatum 70-90 part, Pericarpium Citri Reticulatae 190-210 part, Poria 140-160 part, Radix Glycyrrhizae Preparata 20-40 part, Fructus Mume 50-70 part,
Rhizoma Zingiberis Recenss 110-130 part, Fructus Perillae 70-90 part, Semen Raphani 70-90 part, Semen Sinapis Albae 50-70 part, Rhizoma Alismatis 12-40 part, Caulis Bambusae In Taenia 50-70
Part, Fructus Aurantii Immaturus 70-90 part, Rhizoma Atractylodis Macrocephalae 90-110 part, Radix Aucklandiae 70-90 part, Semen Arecae 20-40 part, Radix Codonopsis 50-70 part, Semen Lablab Album 70-90
Part, Semen Coiciss 110-130 part, Rhizoma dioscoreae 90-110 part, Semen Nelumbinis 50-70 part, Fructus Amomi 20-40 part, Os Draconis 50-70 part, Concha Ostreae
70-90 part.
Preferably, described compositionss also include accessory drugss it is preferable that described accessory drugss include following components by weight:
Ramulus Cinnamomi 10-30 part, Cortex Magnoliae Officinalis 20-40 part, Rhizoma Zingiberiss 50-70 part, Herba Epimedii 10-30 part, Fructus Psoraleae 20-40 part, Semen Persicae
40-60 part, Flos Carthami 50-70 part, Rhizoma Corydalis Decumbentiss 30-50 part, Rhizoma Gastrodiae 50-70 part, Ramulus Uncariae Cum Uncis 50-70 part, Pheretima 20-40 part, Scorpio 20-
40 parts.
Ramulus Cinnamomi, Chinese crude drug Ramulus Cinnamomi is the dry twig of Cortex Cinnamomi, typically harvests in spring, summer, directly dries after going disleaf
Or section dry.Ramulus Cinnamomi pungent-warm, can cold-dispelling, cold, fever with chills etc. can be treated.
Its nature and flavor acrid, sweet, warm, enters lung, the heart, bladder warp, is to cure mainly the drugs for dispelling internal cold that interior cold is commonly used, and has complement sun, logical blood
The effect of arteries and veins, warming the spleen and stomach, often with tonifying liver renal drug, fill blood medicine compatibility, treat insufficiency of kidney-YANG, decline of the fire from the gate of life, cold weak pulse of limb, with it
Its drugs for dispelling internal cold compatibility treatment coldness and pain in the epigastrium, arthralgia due to cold lumbago, have obvious analgesia and the effect of anti-cancer and cancer-preventing.Ramulus Cinnamomi energy diaphoresis solution
Flesh, warming the meridian and promoting blood circulation, helps yang transforming qi, dispersing cold for relieving pain.Main exterior syndrome due to wind-cold;Arthralgia due to cold-dampnes;Extreme cold of the limbs;Closed dysmenorrhea;Lump in the abdomen lumps;
The thoracic obstruction;Cardiopalmus;Phlegm retention;Dysuria.For anemofrigid cold, coldness and pain in the epigastrium, blood trembles with fear Amenorrhea, arthralgia, phlegm retention, edema, the heart
Throb with fear, renal mass.Existing various wind dispelling oils medicine such as menthocamphorate, rheumatism oil etc. all contain cassia oil composition.
Cortex Magnoliae Officinalis, another name ZIPU, purple oil Piao, Wen Piao etc. in the range of botany, to stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO
There is therapeutical effect etc. disease.Can also add in cancer drug.Cortex Magnoliae Officinalis acrid in the mouth, warm in nature, there is circulation of qi promoting removing dampness, warming middle-JIAO to relieve pain, sending down the abnormal ascending QI
The effect relievingd asthma.Cortex Magnoliae Officinalis decoct has stronger antibacterial to make staphylococcuses, streptococcus, bloody dysentery bacillus, pasteurellosis bacilluss, vibrio cholera
With;And also have certain mitigation to band myotonia.
Rhizoma Zingiberiss, acrid in the mouth, property heat.Returns spleen, stomach, kidney, the heart, lung meridian.Warming spleen and stomach for dispelling cold, Back to Yang Tongmai, warming the lung to resolve fluid-retention.For gastral cavity abdomen
Cold type of pain, vomiting is had loose bowels, cold weak pulse of limb, cold fluid-retention is breathed with cough.
Herba Epimedii, acrid-sweet flavor is warm in nature, Return liver kidney channel.Suitable insomniac uses herb hyoscine.Cure mainly impotence and premature ejaculation, the soreness of waist
Skelalgia, numb limbs and tense tendons, hemiplegia, neurasthenia, forgetful, tinnitus, the disease such as dizzy.Herba Epimedii is Chinese conventional Chinese medicine.The kidney invigorating
Tonifying YANG, expelling wind and removing dampness.Control sexual impotence not lift, hemiplegia is unsuccessful, dribbling urination, muscles and bones contraction is anxious, cough, optic atrohic blindness after being ill, toothache caused by fire of deficiency type, half
Body is unsuccessful, weakness of the waist and knees, rheumatic arthralgia, and extremity are meciless.
Fructus Psoraleae, bitter, pungent, warm.Return kidney, spleen channel.Kidney invigorating and YANG supporting, astringent sperm contracting urine, lumbago due to renal deficiency, frequent micturition, children lose
Urine, kidney leaks, warming spleen and stopping diarrha, helping inspiration to relieve asthma.For treatment 1. impotence due to deficiency of the kidney, soreness of the waist and knees cold type of pain, emission due to deficiency of the kidney, the enuresis, frequent micturition.
2. the Diarrhoea that deficiency of spleen-YANG and kidneyYANG causes.3. the deficiency and coldness of failure of the kidney in receiving QI is breathed with cough.
Semen Persicae, bitter, sweet, flat.GUIXIN, liver, large intestine channel.There is blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, effect of relieving cough and asthma.With
In closed dysmenorrhea, lump in the abdomen lump in the abdomen lump in the abdomen, lung abscess acute appendicitis, injury from falling down, dry constipation of intestines, cough and asthma.
Flos Carthami, pungent, temperature.Enter the heart, Liver Channel.The flower of Flos Carthami is used as medicine, and stimulates the menstrual flow, invigorates blood circulation, cures mainly gynaecological disease.Promoting blood circulation to restore menstrual flow, dissipating blood stasis
Pain relieving, contributes to controlling through closing, dysmenorrhea, lochia, obstruction of qi in the chest and cardialgia, stasis of blood, chest side of body shouting pain, traumatic injury, sore swell and ache curative
Curative effect.There are blood circulation promoting and blood stasis dispelling, effect of dissipate wet effect going to swell, it is to avoid anemia of pregnant woman uses, otherwise can cause to miscarry.Promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving.
Controlling through closing, lump in the abdomen, difficult labour, stillborn fetuses, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.
Rhizoma Corydalis Decumbentiss, bitter in the mouth, micro-pungent, warm in nature.Return liver warp.There are active, the promoting the circulation of QI to relieve pain of promoting blood circulation, expelling wind and removing dampness has effect.For
Apoplectic hemiplegia, headache, injury from falling down, rheumatic arthralgia, lumbago and skelalgia.
Rhizoma Gastrodiae, sweet, put down, enter Liver Channel.Just it is related to the record of Rhizoma Gastrodiae in Shennong's Herbal, claim " rhizoma gastrodiae ", Shen Kuo
Described in " mengxibitan ": " puzzled the saying in Rhizoma Gastrodiae of common people, only controls wind with it then, good unfortunately ".Li Shizhen (1518-1593 A.D.) Compendium of Material Medica
Specially this is illustrated, claims the name of " Rhizoma Gastrodiae ", for " descendant's referred to as Rhizoma Gastrodiae ".Endogenous wind stopping, arresting convulsion.Control dizziness pupil, head wind headache, limb
Body is numb, hemiplegia, aphasia, pediatric epilepsy scared wind symptom.
Ramulus Uncariae Cum Uncis is sweet, is slightly cold.Return liver, pericardium channel.Ramulus Uncariae Cum Uncis is used as medicine with the stem branch of buckle, and it has The flat liver of heat-clearing, dispelling wind and relieving convulsion
Effect, modern pharmacology experiment also confirms that Ramulus Uncariae Cum Uncis has hypotensive effect, therefore has very high medical value.Ramulus Uncariae Cum Uncis is to be dried buckle stem
Branch is used as medicine.There is the function of calmness, blood pressure lowering, The flat liver of heat-clearing, dispelling wind and relieving convulsion, for dizziness of having a headache, dysphoric cold, twitch,
Pre-eclampsia, the disease such as hypertension.It is one of first-selected medical material for the treatment of cardiovascular and cerebrovascular disease, clinically have long application to go through
History.
Pheretima, salty, tremble with fear.Return liver, spleen, bladder warp.It is one of important Chinese crude drug of China.Earliest Chinese materia medica monograph " god
Agriculture book on Chinese herbal medicine warp " in just have Lumbricuss in 67 kinds of animal drugs recording.It is classified as low-grades in Shennong's Herbal, there is heat clearing away arresting convulsion, lead to
Network, relieving asthma, effect of diuresis.Often after parch for hyperpyrexia, coma, twitch, arthralgia, dyspnea and cough due to lung-heat, oliguria edema,
The diseases such as hypertension.Master contains several amino acids.Because health product fishy smell is too heavy, therefore be used as medicine typically need to be through parch.TAO Hong-Jing is called: " if clothes
Dry earthworm, must endure and consider to be worth doing ".Tradition uses Pheretima, and preparation method is a lot, mainly have medicine system, vinegar system, boil, processed with wine, oily system, Pulvis concha Mactrae parch, salt
System etc. method so as to quality pine bubble crisp, go toxicity, correct stink and be easy to fried taking.
Scorpio, pungent, put down.Return liver warp.Endogenous wind stopping spasmolytic, removing obstruction in the collateral to relieve pain, dispersing pathogen accumulation.For liver-wind stirring up internally, spasm is twitched, little
Youngster's infantile convulsion, middle air port, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.
Another aspect of the present invention relates to improve the medicine brick of phlegm-dampness constitution, and described medicine brick is mainly by described medicine group
Compound and loess are made.
Preferably, the weight ratio of described loess and described pharmaceutical composition is: (0.5-2): 1.
Another aspect of the present invention is related to the preparation method of described medicine brick, the method comprising the steps of:
1) Rhizoma Pinelliae Preparatum, Pericarpium Citri Reticulatae, Poria, Radix Glycyrrhizae Preparata, Fructus Mume, Rhizoma Zingiberis Recenss are added water to cook to obtain ERCHEN TANG;By Fructus Perillae, Semen Sinapis Albae,
Semen Raphani adds water to cook and obtains sanzi yangqin decoction;
2) described ERCHEN TANG and sanzi yangqin decoction are mixed and concentrating under reduced pressure obtains middle concentrated solution;
3) described middle concentrated solution is placed in jacketed pan and continues to concentrate, obtain final concentrated solution;
4) by Rhizoma Alismatis, Caulis Bambusae In Taenia, Fructus Aurantii Immaturus, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Semen Arecae, Radix Codonopsis, Semen Lablab Album, Semen Coiciss, Rhizoma dioscoreae, Semen Nelumbinis, sand
Core, Os Draconis, Concha Ostreae are respectively prepared decoction pieces, after pulverizing and mixing, and are mixed to prepare mixture with described final concentrated solution;
5) by described mixture punch forming and drying and shaping, finished product medicine brick.
Preferably, the step 4 of methods described) in, by Ramulus Cinnamomi, Cortex Magnoliae Officinalis, Rhizoma Zingiberiss, Herba Epimedii, Fructus Psoraleae, Semen Persicae, Flos Carthami, summer
Its nothing, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Pheretima, Scorpio are pulverized after being also respectively prepared decoction pieces, mix with the decoction pieces ground product of other components, and one
It is mixed to prepare mixture with described final concentrated solution.
Preferably, described middle concentrated solution, the relative density when 50 DEG C is 1.05-1.08g/cm3;Described final concentration
The relative density when 50 DEG C for the liquid is 1.30-1.35g/cm3.
Preferably, described step 1) in, decoct and carry out twice, the weight adding water every time is to treat decocting herbs gross weight
8-12 times, each decocting time is 50-70min, and after decocting every time, filtrate crosses 300 mesh sieves.
Preferably, described step 5) in, the pressing time in punching course is 2-3min, and drying temperature is 40-45 DEG C, excellent
Selection of land, baking duration is 1.5-2.5h.
Compared with prior art, the invention has the benefit that
The pharmaceutical composition of the present invention can improve phlegm-dampness constitution effectively, and especially adapts to the administration of heating topical administration
Mode;
The medicine brick of the present invention is mixed with loess by described pharmaceutical composition, can pass through heating release drug well
Active substances, reach therapeutic effect;
The preparation method that the present invention provides, process is clearly it is easy to control, favorable reproducibility.
Specific embodiment
Below in conjunction with embodiment, embodiment of the present invention is described in detail, but those skilled in the art will
Understand, the following example is merely to illustrate the present invention, and be not construed as limiting the scope of the present invention.Unreceipted concrete in embodiment
Condition person, the condition according to normal condition or manufacturer's suggestion is carried out.Agents useful for same or the unreceipted production firm person of instrument, are
Can be by the commercially available conventional products bought and obtain.
Embodiment 1
Prepare the medicine brick for treating yin-deficiency constitution in accordance with the following steps
1. prepare the loess of following raw material by weight and medical material gross weight 1 times amount
60 parts of Rhizoma Pinelliae Preparatum, 180 parts of Pericarpium Citri Reticulatae, 130 parts of Poria, 10 parts of Radix Glycyrrhizae Preparata, 40 parts of Fructus Mume, 100 parts of Rhizoma Zingiberis Recenss, Fructus Perillae 60
Part, 60 parts of Semen Raphani, 40 parts of Semen Sinapis Albae, 10 parts of Rhizoma Alismatis, 40 parts of Caulis Bambusae In Taenia, 60 parts of Fructus Aurantii Immaturus, 80 parts of the Rhizoma Atractylodis Macrocephalae, 60 parts of the Radix Aucklandiae, Semen Arecae 10
Part, 40 parts of Radix Codonopsis, 60 parts of Semen Lablab Album, 100 parts of Semen Coiciss, 80 parts of Rhizoma dioscoreae, 40 parts of Semen Nelumbinis, 10 parts of Fructus Amomi, 40 parts of Os Draconis, male
60 parts of oyster.
2. Rhizoma Pinelliae Preparatum, Pericarpium Citri Reticulatae, Poria, Radix Glycyrrhizae Preparata, Fructus Mume, Rhizoma Zingiberis Recenss are added water to cook to obtain ERCHEN TANG;By Fructus Perillae, Semen Sinapis Albae,
Semen Raphani adds water to cook and obtains sanzi yangqin decoction;Decoction carries out twice, and the weight adding water every time is to treat decocting herbs gross weight
8 times, each decocting time is 50min, and after decocting every time, filtrate crosses 300 mesh sieves.
3. described ERCHEN TANG and sanzi yangqin decoction are mixed and concentrating under reduced pressure obtains concentrated solution in the middle of described in middle concentrated solution,
Relative density when 50 DEG C is 1.05g/cm3;
4. described middle concentrated solution is placed in jacketed pan and continues to concentrate, obtain final concentrated solution, described final concentrated solution exists
Relative density when 50 DEG C is 1.30g/cm3;
5. by Rhizoma Alismatis, Caulis Bambusae In Taenia, Fructus Aurantii Immaturus, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Semen Arecae, Radix Codonopsis, Semen Lablab Album, Semen Coiciss, Rhizoma dioscoreae, Semen Nelumbinis, sand
Core, Os Draconis, Concha Ostreae are respectively prepared decoction pieces, after pulverizing and mixing, are mixed to prepare mixture with described final concentrated solution;
6., by described mixture punch forming and drying and shaping, finished product medicine brick, wherein, during pressurization in punching course
Between be 2min, drying temperature be 40 DEG C, baking duration be 1.5h.
Embodiment 2
Prepare the medicine brick for treating yin-deficiency constitution in accordance with the following steps
1. prepare the loess of following raw material by weight and medical material gross weight 0.5 times amount
100 parts of Rhizoma Pinelliae Preparatum, 220 parts of Pericarpium Citri Reticulatae, 170 parts of Poria, 50 parts of Radix Glycyrrhizae Preparata, 80 parts of Fructus Mume, 140 parts of Rhizoma Zingiberis Recenss, Fructus Perillae 100
Part, 100 parts of Semen Raphani, 80 parts of Semen Sinapis Albae, 50 parts of Rhizoma Alismatis, 80 parts of Caulis Bambusae In Taenia, 100 parts of Fructus Aurantii Immaturus, 120 parts of the Rhizoma Atractylodis Macrocephalae, 100 parts of the Radix Aucklandiae, Bin
Bulky 50 parts, 80 parts of Radix Codonopsis, 100 parts of Semen Lablab Album, 140 parts of Semen Coiciss, 120 parts of Rhizoma dioscoreae, 80 parts of Semen Nelumbinis, 50 parts of Fructus Amomi, Os Draconis
80 parts, 100 parts of Concha Ostreae.
2. Rhizoma Pinelliae Preparatum, Pericarpium Citri Reticulatae, Poria, Radix Glycyrrhizae Preparata, Fructus Mume, Rhizoma Zingiberis Recenss are added water to cook to obtain ERCHEN TANG;By Fructus Perillae, Semen Sinapis Albae,
Semen Raphani adds water to cook and obtains sanzi yangqin decoction;Decoction carries out twice, and the weight adding water every time is to treat decocting herbs gross weight
12 times, each decocting time is 70min, and after decocting every time, filtrate crosses 300 mesh sieves.
3. described ERCHEN TANG and sanzi yangqin decoction are mixed and concentrating under reduced pressure obtains concentrated solution in the middle of described in middle concentrated solution,
Relative density when 50 DEG C is 1.08g/cm3;
4. described middle concentrated solution is placed in jacketed pan and continues to concentrate, obtain final concentrated solution, described final concentrated solution exists
Relative density when 50 DEG C is 1.35g/cm3;
5. by Rhizoma Alismatis, Caulis Bambusae In Taenia, Fructus Aurantii Immaturus, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Semen Arecae, Radix Codonopsis, Semen Lablab Album, Semen Coiciss, Rhizoma dioscoreae, Semen Nelumbinis, sand
Core, Os Draconis, Concha Ostreae are respectively prepared decoction pieces, after pulverizing and mixing, are mixed to prepare mixture with described final concentrated solution;
6., by described mixture punch forming and drying and shaping, finished product medicine brick, wherein, during pressurization in punching course
Between be 3min, drying temperature be 45 DEG C, baking duration be 2.5h.
Embodiment 3
Prepare the medicine brick for treating yin-deficiency constitution in accordance with the following steps
1. prepare the loess of following raw material by weight and medical material gross weight 2 times amount
70 parts of Rhizoma Pinelliae Preparatum, 190 parts of Pericarpium Citri Reticulatae, 140 parts of Poria, 20 parts of Radix Glycyrrhizae Preparata, 50 parts of Fructus Mume, 110 parts of Rhizoma Zingiberis Recenss, Fructus Perillae 70
Part, 70 parts of Semen Raphani, 50 parts of Semen Sinapis Albae, 12 parts of Rhizoma Alismatis, 50 parts of Caulis Bambusae In Taenia, 70 parts of Fructus Aurantii Immaturus, 90 parts of the Rhizoma Atractylodis Macrocephalae, 70 parts of the Radix Aucklandiae, Semen Arecae 20
Part, 50 parts of Radix Codonopsis, 70 parts of Semen Lablab Album, 110 parts of Semen Coiciss, 90 parts of Rhizoma dioscoreae, 50 parts of Semen Nelumbinis, Fructus Amomi 20-40 part, Os Draconis 50
Part, 70 parts of Concha Ostreae, 10 parts of Ramulus Cinnamomi, 20 parts of Cortex Magnoliae Officinalis, 50 parts of Rhizoma Zingiberiss, 10 parts of Herba Epimedii, 20 parts of Fructus Psoraleae, 40 parts of Semen Persicae, Flos Carthami 50
Part, 30 parts of Rhizoma Corydalis Decumbentiss, 50 parts of Rhizoma Gastrodiae, 50 parts of Ramulus Uncariae Cum Uncis, 20 parts of Pheretima, 20 parts of Scorpio.
2. Rhizoma Pinelliae Preparatum, Pericarpium Citri Reticulatae, Poria, Radix Glycyrrhizae Preparata, Fructus Mume, Rhizoma Zingiberis Recenss are added water to cook to obtain ERCHEN TANG;By Fructus Perillae, Semen Sinapis Albae,
Semen Raphani adds water to cook and obtains sanzi yangqin decoction;Decoction carries out twice, and the weight adding water every time is to treat decocting herbs gross weight
12 times, each decocting time is 70min, and after decocting every time, filtrate crosses 300 mesh sieves.
3. described ERCHEN TANG and sanzi yangqin decoction are mixed and concentrating under reduced pressure obtains concentrated solution in the middle of described in middle concentrated solution,
Relative density when 50 DEG C is 1.08g/cm3;
4. described middle concentrated solution is placed in jacketed pan and continues to concentrate, obtain final concentrated solution, described final concentrated solution exists
Relative density when 50 DEG C is 1.35g/cm3;
5. by Rhizoma Alismatis, Caulis Bambusae In Taenia, Fructus Aurantii Immaturus, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Semen Arecae, Radix Codonopsis, Semen Lablab Album, Semen Coiciss, Rhizoma dioscoreae, Semen Nelumbinis, sand
Core, Os Draconis, Concha Ostreae, Ramulus Cinnamomi, Cortex Magnoliae Officinalis, Rhizoma Zingiberiss, Herba Epimedii, Fructus Psoraleae, Semen Persicae, Flos Carthami, Rhizoma Corydalis Decumbentiss, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Pheretima, complete
Scorpion is respectively prepared decoction pieces, after pulverizing and mixing, is mixed to prepare mixture with described final concentrated solution;
6., by described mixture punch forming and drying and shaping, finished product medicine brick, wherein, during pressurization in punching course
Between be 3min, drying temperature be 45 DEG C, baking duration be 2.5h.
Embodiment 4
Prepare the medicine brick for treating yin-deficiency constitution in accordance with the following steps
1. prepare the loess of following raw material by weight and medical material gross weight 1 times amount
90 parts of Rhizoma Pinelliae Preparatum, 210 parts of Pericarpium Citri Reticulatae, 160 parts of Poria, 40 parts of Radix Glycyrrhizae Preparata, 70 parts of Fructus Mume, 130 parts of Rhizoma Zingiberis Recenss, Fructus Perillae 90
Part, 90 parts of Semen Raphani, 70 parts of Semen Sinapis Albae, 40 parts of Rhizoma Alismatis, 70 parts of Caulis Bambusae In Taenia, 90 parts of Fructus Aurantii Immaturus, 110 parts of the Rhizoma Atractylodis Macrocephalae, 90 parts of the Radix Aucklandiae, Semen Arecae 40
Part, 70 parts of Radix Codonopsis, 90 parts of Semen Lablab Album, 130 parts of Semen Coiciss, 110 parts of Rhizoma dioscoreae, 70 parts of Semen Nelumbinis, 40 parts of Fructus Amomi, 70 parts of Os Draconis,
90 parts of Concha Ostreae, 30 parts of Ramulus Cinnamomi, 40 parts of Cortex Magnoliae Officinalis, 70 parts of Rhizoma Zingiberiss, 30 parts of Herba Epimedii, 40 parts of Fructus Psoraleae, 60 parts of Semen Persicae, 70 parts of Flos Carthami,
50 parts of Rhizoma Corydalis Decumbentiss, Rhizoma Gastrodiae 50-70 part, 70 parts of Ramulus Uncariae Cum Uncis, 40 parts of Pheretima, 40 parts of Scorpio.
2. Rhizoma Pinelliae Preparatum, Pericarpium Citri Reticulatae, Poria, Radix Glycyrrhizae Preparata, Fructus Mume, Rhizoma Zingiberis Recenss are added water to cook to obtain ERCHEN TANG;By Fructus Perillae, Semen Sinapis Albae,
Semen Raphani adds water to cook and obtains sanzi yangqin decoction;Decoction carries out twice, and the weight adding water every time is to treat decocting herbs gross weight
10 times, each decocting time is 65min, and after decocting every time, filtrate crosses 300 mesh sieves.
3. described ERCHEN TANG and sanzi yangqin decoction are mixed and concentrating under reduced pressure obtains concentrated solution in the middle of described in middle concentrated solution,
Relative density when 50 DEG C is 1.07g/cm3;
4. described middle concentrated solution is placed in jacketed pan and continues to concentrate, obtain final concentrated solution, described final concentrated solution exists
Relative density when 50 DEG C is 1.33g/cm3;
5. by Rhizoma Alismatis, Caulis Bambusae In Taenia, Fructus Aurantii Immaturus, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Semen Arecae, Radix Codonopsis, Semen Lablab Album, Semen Coiciss, Rhizoma dioscoreae, Semen Nelumbinis, sand
Core, Os Draconis, Concha Ostreae, Ramulus Cinnamomi, Cortex Magnoliae Officinalis, Rhizoma Zingiberiss, Herba Epimedii, Fructus Psoraleae, Semen Persicae, Flos Carthami, Rhizoma Corydalis Decumbentiss, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Pheretima, complete
Scorpion is respectively prepared decoction pieces, after pulverizing and mixing, is mixed to prepare mixture with described final concentrated solution;
6., by described mixture punch forming and drying and shaping, finished product medicine brick, wherein, during pressurization in punching course
Between be 2min, drying temperature be 42 DEG C, baking duration be 1.5h.
Embodiment 5
Prepare the medicine brick for treating yin-deficiency constitution in accordance with the following steps
1. prepare the loess of following raw material by weight and medical material gross weight 1.5 times amount
80 parts of Rhizoma Pinelliae Preparatum, 200 parts of Pericarpium Citri Reticulatae, 150 parts of Poria, 30 parts of Radix Glycyrrhizae Preparata, 60 parts of Fructus Mume, 120 parts of Rhizoma Zingiberis Recenss, Fructus Perillae 80
Part, 80 parts of Semen Raphani, 60 parts of Semen Sinapis Albae, 30 parts of Rhizoma Alismatis, 60 parts of Caulis Bambusae In Taenia, 80 parts of Fructus Aurantii Immaturus, 100 parts of the Rhizoma Atractylodis Macrocephalae, 80 parts of the Radix Aucklandiae, Semen Arecae 30
Part, 60 parts of Radix Codonopsis, 80 parts of Semen Lablab Album, 120 parts of Semen Coiciss, 100 parts of Rhizoma dioscoreae, 60 parts of Semen Nelumbinis, 30 parts of Fructus Amomi, 20 parts of Ramulus Cinnamomi,
30 parts of Cortex Magnoliae Officinalis, 60 parts of Rhizoma Zingiberiss, 20 parts of Herba Epimedii, 30 parts of Fructus Psoraleae, 50 parts of Semen Persicae, 60 parts of Flos Carthami, 40 parts of Rhizoma Corydalis Decumbentiss, Os Draconis 60
Part, 80 parts of Concha Ostreae, 60 parts of Rhizoma Gastrodiae, 60 parts of Ramulus Uncariae Cum Uncis, 30 parts of Pheretima, 30 parts of Scorpio.
2. Rhizoma Pinelliae Preparatum, Pericarpium Citri Reticulatae, Poria, Radix Glycyrrhizae Preparata, Fructus Mume, Rhizoma Zingiberis Recenss are added water to cook to obtain ERCHEN TANG;By Fructus Perillae, Semen Sinapis Albae,
Semen Raphani adds water to cook and obtains sanzi yangqin decoction;Decoction carries out twice, and the weight adding water every time is to treat decocting herbs gross weight
12 times, each decocting time is 70min, and after decocting every time, filtrate crosses 300 mesh sieves.
3. described ERCHEN TANG and sanzi yangqin decoction are mixed and concentrating under reduced pressure obtains concentrated solution in the middle of described in middle concentrated solution,
Relative density when 50 DEG C is 1.06g/cm3;
4. described middle concentrated solution is placed in jacketed pan and continues to concentrate, obtain final concentrated solution, described final concentrated solution exists
Relative density when 50 DEG C is 1.32g/cm3;
5. by Rhizoma Alismatis, Caulis Bambusae In Taenia, Fructus Aurantii Immaturus, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Semen Arecae, Radix Codonopsis, Semen Lablab Album, Semen Coiciss, Rhizoma dioscoreae, Semen Nelumbinis, sand
Core, Os Draconis, Concha Ostreae, Ramulus Cinnamomi, Cortex Magnoliae Officinalis, Rhizoma Zingiberiss, Herba Epimedii, Fructus Psoraleae, Semen Persicae, Flos Carthami, Rhizoma Corydalis Decumbentiss, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Pheretima, complete
Scorpion is respectively prepared decoction pieces, after pulverizing and mixing, is mixed to prepare mixture with described final concentrated solution;
6., by described mixture punch forming and drying and shaping, finished product medicine brick, wherein, during pressurization in punching course
Between be 3min, drying temperature be 42 DEG C, baking duration be 2h.
Experimental example
Enlist the volunteer of 500 phlegm-dampness constitutions, be equally divided into 5 groups, group 1-5 is respectively using preparation in embodiment 1-5
Medicine brick cooperation health-preserving heated brick bed carries out Experiment on therapy, after treating two weeks, the phlegm-damp situation of its body constitution is tested and assessed, and is finally given
The evaluation of therapeutic effect, evaluate be divided into, in, differ from three kinds;Wherein, phlegm-dampness constitution be improved significantly, phlegm-damp symptom is substantially complete
Totally disappeared being chosen as of mistake;Phlegm-dampness constitution is effectively improved, in being chosen as of phlegm-damp symptom partial disappearance;Phlegm-dampness constitution no changes substantially
Kind, being chosen as of the nearly no disappearance of the symptom that phlegm-damp leads to is poor, obtains volunteer's demographics result such as following table institute of each evaluation
Show.
Group/effect assessment | Good | In | Difference |
1 | 76 | 15 | 9 |
2 | 84 | 13 | 3 |
3 | 89 | 11 | 0 |
4 | 95 | 5 | 0 |
5 | 93 | 7 | 0 |
As can be seen from the above table, the medicine brick of the present invention, especially according to the medicine brick of preferred ingredient proportioning of the present invention preparation,
Treatment phlegm-dampness constitution aspect effective percentage is high.
Although illustrate and describing the present invention with specific embodiment, but it will be appreciated that without departing substantially from the present invention's
Many other changes can be made in the case of spirit and scope and change.It is, therefore, intended that in the following claims
Including all such changes and modifications belonging in the scope of the invention.
Claims (10)
1. a kind of pharmaceutical composition improving phlegm-dampness constitution it is characterised in that described compositionss include by weight following
Component:
Rhizoma Pinelliae Preparatum 60-100 part, Pericarpium Citri Reticulatae 180-220 part, Poria 130-170 part, Radix Glycyrrhizae Preparata 10-50 part, Fructus Mume 40-80 part, Rhizoma Zingiberis Recenss
100-140 part, Fructus Perillae 60-100 part, Semen Raphani 60-100 part, Semen Sinapis Albae 40-80 part, Rhizoma Alismatis 10-50 part, Caulis Bambusae In Taenia 40-80 part,
Fructus Aurantii Immaturus 60-100 part, Rhizoma Atractylodis Macrocephalae 80-120 part, Radix Aucklandiae 60-100 part, Semen Arecae 10-50 part, Radix Codonopsis 40-80 part, Semen Lablab Album 60-100
Part, Semen Coiciss 100-140 part, Rhizoma dioscoreae 80-120 part, Semen Nelumbinis 40-80 part, Fructus Amomi 10-50 part, Os Draconis 40-80 part, Concha Ostreae
60-100 part.
2. pharmaceutical composition according to claim 1 it is characterised in that described compositionss include by weight following
Component:
Rhizoma Pinelliae Preparatum 70-90 part, Pericarpium Citri Reticulatae 190-210 part, Poria 140-160 part, Radix Glycyrrhizae Preparata 20-40 part, Fructus Mume 50-70 part, Rhizoma Zingiberis Recenss
110-130 part, Fructus Perillae 70-90 part, Semen Raphani 70-90 part, Semen Sinapis Albae 50-70 part, Rhizoma Alismatis 12-40 part, Caulis Bambusae In Taenia 50-70 part, trifoliate orange
Real 70-90 part, Rhizoma Atractylodis Macrocephalae 90-110 part, Radix Aucklandiae 70-90 part, Semen Arecae 20-40 part, Radix Codonopsis 50-70 part, Semen Lablab Album 70-90 part, Semen Coiciss
Core 110-130 part, Rhizoma dioscoreae 90-110 part, Semen Nelumbinis 50-70 part, Fructus Amomi 20-40 part, Os Draconis 50-70 part, Concha Ostreae 70-90 part.
3. pharmaceutical composition according to claim 1 is it is characterised in that described compositionss also include accessory drugss it is preferable that institute
State the following components that accessory drugss include by weight:
Ramulus Cinnamomi 10-30 part, Cortex Magnoliae Officinalis 20-40 part, Rhizoma Zingiberiss 50-70 part, Herba Epimedii 10-30 part, Fructus Psoraleae 20-40 part, Semen Persicae 40-60
Part, Flos Carthami 50-70 part, Rhizoma Corydalis Decumbentiss 30-50 part, Rhizoma Gastrodiae 50-70 part, Ramulus Uncariae Cum Uncis 50-70 part, Pheretima 20-40 part, Scorpio 20-40 part.
4. a kind of medicine brick for improving phlegm-dampness constitution is it is characterised in that described medicine brick is mainly by any one in claim 1-3
Pharmaceutical composition described in and loess are made.
5. medicine brick according to claim 4 is it is characterised in that the weight ratio of described loess and described pharmaceutical composition is:
(0.5-2):1.
6. the preparation method of the medicine brick described in claim 4 or 5 is it is characterised in that the method comprising the steps of:
1) Rhizoma Pinelliae Preparatum, Pericarpium Citri Reticulatae, Poria, Radix Glycyrrhizae Preparata, Fructus Mume, Rhizoma Zingiberis Recenss are added water to cook to obtain ERCHEN TANG;By Fructus Perillae, Semen Sinapis Albae, Radix Raphani
Son adds water to cook and obtains sanzi yangqin decoction;
2) described ERCHEN TANG and sanzi yangqin decoction are mixed and concentrating under reduced pressure obtains middle concentrated solution;
3) described middle concentrated solution is placed in jacketed pan and continues to concentrate, obtain final concentrated solution;
4) by Rhizoma Alismatis, Caulis Bambusae In Taenia, Fructus Aurantii Immaturus, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Semen Arecae, Radix Codonopsis, Semen Lablab Album, Semen Coiciss, Rhizoma dioscoreae, Semen Nelumbinis, Fructus Amomi,
Os Draconis, Concha Ostreae are respectively prepared decoction pieces, after pulverizing and mixing, are mixed to prepare mixture with described final concentrated solution;
5) by described mixture punch forming and drying and shaping, finished product medicine brick.
7. method according to claim 6 is it is characterised in that the step 4 of methods described) in, by Ramulus Cinnamomi, Cortex Magnoliae Officinalis, Rhizoma Zingiberiss,
Herba Epimedii, Fructus Psoraleae, Semen Persicae, Flos Carthami, Rhizoma Corydalis Decumbentiss, Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Pheretima, Scorpio are pulverized, with other after being also respectively prepared decoction pieces
The decoction pieces ground product mixing of component, and together it is mixed to prepare mixture with described final concentrated solution.
8. it is characterised in that described middle concentrated solution, the relative density when 50 DEG C is method according to claim 6
1.05-1.08g/cm3;The relative density when 50 DEG C for the described final concentrated solution is 1.30-1.35g/cm3.
9. method according to claim 6 is it is characterised in that described step 1) in, decoct and carry out twice, add water every time
Weight be treat decocting herbs gross weight 8-12 times, each decocting time is 50-70min, and after decocting every time, filtrate crosses 300 mesh
Sieve.
10. method according to claim 6 is it is characterised in that described step 5) in, the pressing time in punching course is
2-3min, drying temperature is 40-45 DEG C it is preferable that baking duration is 1.5-2.5h.
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CN113694162A (en) * | 2021-09-10 | 2021-11-26 | 哈尔滨物粹堂药业有限公司 | Traditional Chinese medicine formula for conditioning body functions |
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CN107412619A (en) * | 2017-08-15 | 2017-12-01 | 山东仲景健康服务有限公司 | One kind is for phlegm-dampness constitution massage Chinese medicine oil breast |
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