CN106333886A - Composition having moisture preserving and skin whitening and brightening effects and application thereof - Google Patents
Composition having moisture preserving and skin whitening and brightening effects and application thereof Download PDFInfo
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/02—Algae
- A61K36/04—Rhodophycota or rhodophyta (red algae), e.g. Porphyra
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A61Q19/00—Preparations for care of the skin
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K38/00—Medicinal preparations containing peptides
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Abstract
The invention discloses a composition having moisture preserving and skin whitening and brightening effects. The composition is prepared from, by weight, 0.5-3 parts of sweet melon extract, 0.5-3 parts of wild soybean seed extract and 0.5-3 parts of coralline algae extract. The composition is prepared from the natural plant extracts, is mild and non-irritant and has the effects of achieving instant moisture preserving and long-lasting moisture preserving, promoting collagen neogenesis among the skin cells, promoting wound repair and decreasing the melanin and red pigment content. In addition, the invention further discloses a cosmetic containing the composition.
Description
Technical field
The present invention relates to a kind of compositionss and its application are and in particular to a kind of combination with moisturizing and whitening skin lightening
Thing and its application.
Background technology
Moisturizing, is that skin protection cosmeticss are most important, is also most basic functional requirement.Why skin wants moisturizing, Wo Menxian
Talk about from the physiological function of skin.Skin divides epidermis, corium and subcutaneous fat.The outermost layer of epidermis is horny layer, due to angle
In the water suction of matter layer itself, barrier function, and horny layer, contained nature moisturizing factor is amino acidses, lactate and sugar
The effect of class etc., makes horny layer keep certain water content, maintains the moistening of skin.And the outward appearance of skin and cuticular moisture
Content is relevant, and normal keratodermatitis usually contain 10%～30% moisture, to maintain softness and the elasticity of skin.But with
The impact of external environment or the growth at age, keratodermatitis moisture can gradually decrease, and works as the water of keratodermatitis
When point content is less than 10%, skin arises that dry, tight, coarse and desquamation etc..These are all due to moisture of skin moisturizing
Degree is not directly related, does not have water, all things on earth will be withered.Therefore, all kinds of Moisturizers are always cosmetic technical field and open
The emphasis sent out.
Moisturizing class cosmetics are a lot of on the market at present, but the raw material that most of replenishing water and preserving moisture cosmetics apply to is mainly
Polyalcohols, such as glycerol, propylene glycol, butanediol, Sorbitol；Small molecule class, such as trimethyl glycine (glycine betaine), ethoxy urine
Element, pca.na, lactic acid, sodium lactate, Fructose；Natural polymerization species: as hyaluronate sodium, polyglutamic acid, glucose, neural acyl
Amine；Synthesis class: glycerin polyether～26, polyglycerolmethacrylate (reed fragrant plant glue) etc..These raw materials can bring moment moisturizing to protect
Wet effect, but continue the effect of moisturizing water lock bad, and also these raw materials are synthesis material mostly, and skin is had necessarily
Stimulation.Therefore searching has lasting moisturizing, the skin care compositionss of whitening skin lightening multiple efficacies are current cosmetic technical field
Need the pressing issues solving.
Content of the invention
It is an object of the invention to providing in place of overcoming the deficiencies in the prior art, one kind has moisturizing and whitening skin lightening is made
Compositionss and its application.
For achieving the above object, the technical scheme that the present invention takes is: a kind of group with moisturizing and whitening skin lightening
Compound, in parts by weight, including following components: 0.5～3 part of Fructus Melo berry extract, 0.5～3 part of Wild soybean seed extract, Corallium Japonicum Kishinouye
0.5～3 part of algae extract.
Preferably, described compositionss also include Flos Matricariae chamomillae flower extract and/or Herba Centellae extract, described Flos Matricariae chamomillae flower extract
For 0.3～3 weight portion, described Herba Centellae extract is 0.3～3 weight portion.
It is highly preferred that described compositionss also comprise glycoprotein.
It is highly preferred that described glycoprotein is 0.5～3 weight portion.
Preferably, the described compositionss with moisturizing and whitening skin lightening, in parts by weight, comprise following components: sweet
2.5 parts of melon and fruit extract, 1 part of Wild soybean seed extract, 1 part of Corallium Japonicum Kishinouye algae extract, 2.5 parts of Flos Matricariae chamomillae flower extract, Herba Centellae carry
Take 1 part of thing, 0.1 part of glycoprotein.
Composition in compositionss of the present invention is commercial goods, and described composition is by natural plant extracts, temperature
With non-stimulated, effect of wherein each composition is as follows:
Fructus Melo berry extract contain protein, carbohydrate, carotene, vitamin b1, vitamin b2, nicotinic acid, calcium,
The nutrients such as phosphorus, ferrum, can increase skin-nourishing, make skin keep moistening, promote skin self-regeneration, make skin recover normal
State.
The aminoacid composition of the Wild soybean protein in Wild soybean seed extract and animal protein are approximate, wherein aminoacid
The ratio that relatively human body needs, supplements nutrition and the moisture content that skin loses in time, rebuilds skin care film, the dry skin of order
Skin is recaptured moist, makes nutrition fully absorb.
Corallium Japonicum Kishinouye algae extract contains abundant marine ferment, collagen protein and has abundant mineral, has " seabed Nidus collocaliae "
Good name.Coralline algae extract has and improves wrinkle, black speck as more having the positive effect of toxin expelling, for the water-retaining property of skin, tight
Adding of contracting and elasticity etc. also has obvious effect, and it becomes possible to significantly improve keratodermatitis under relatively low consumption
Moisture retention.
Flos Chrysanthemi also known as Flos Matricariae chamomillae, camomile extract is derived from the head titbit of feverfew chrysanthemum, includes volatile oil, gallbladder
Multiple active ingredients such as alkali, stachydrine, aminoacid, flavonoid and micro-element b1, Flos Chrysanthemi lactone, chrysanthone, chrysol.This extraction
Thing can not only improve sensitivity, hydropenia, the skin peeled is dried, and increase skin elasticity, and some skin pathogenicity funguses are had
There are suppression and bactericidal action.Make an addition to the cleansing milk in cosmetics, protective skin cream, massage cream, there is good skin protection, U.S. in facial film
Skin therapeutical effect.
Herba Centellae extract used in the present invention is the standard extract obtaining from samphire Herba Centellae.It is also
Be referred to as India's Graptopelaum Paraguayense, Herba Centellae system herbaceos perennial, blade is little and justify, closely heart-shaped, be longer than at long shoot bottom node,
Easily recognize.Umbel, spends little, is umbelliferous feature.Contain important composition in Herba Centellae, such as: essential oil, sterin,
Flavonol, join saccharide, polyethylene and saponin.Herba Centellae (being embodied in Ayurveda) ancient times just have been used, and tradition is used
In treatment dermatitis and healing skin superficial wound.Brain-strengthening tonic also can be made simultaneously.In recent years, scientist is the treatment of Herba Centellae
Effect is attributed to it and contains asiaticoside and its derivant.Herba Centellae extract is mainly used in auxiliary treatment surgical incision and heals
Close the recovery with some small-area burns.It can be used for the supplement therapy of leg ulcer (granulating the stage on surface).Accumulated snow
Careless extract oral can improve lymphsystem and vein blood vessel circulation, hence helps to wound healing.Accumulated snow in cosmetics
Careless extract can improve enzyme type and non-enzyme type polyphenoils dismutase, hydrogen peroxide, Agifutol peroxide in newly-generated tissue
Change enzyme, the content of vitamin e and ascorbic acid c, further demonstrate its skin and complexion improving effect.Herba Centellae extract quilt
Otc skin nursing is recommended to smooth (can after plastic operation using) for ageing skin regeneration and cicatrix.In the present invention, accumulated snow
Careless extract has moisturizing reparation and alleviates skin irritant effect.
Described glycoprotein has the restoring force proliferation function of strengthening cell, strengthens skin immune system effect.
The compositionss of the present invention are made up of natural plant extracts, gently non-stimulated, and have instant moisturizing, long-acting guarantor
Wet, promoting collagen protein between Skin Cell newborn, promoting wound repair, the content of minimizing melanin and red pigment is thus reach
The effect of skin lightening.
Meanwhile, present invention also offers a kind of cosmetics containing described compositionss, medicine or nursing product.
Preferably, described cosmetics also include wetting agent, and described wetting agent is 2～16 weight portions.
It is highly preferred that described wetting agent includes 1～8 parts by weight of propylene glycol and 1～8 weight portion butanediol.Described propylene glycol
It is mainly used for moisture-keeping function with butanediol, also have certain bacteriostasis simultaneously.Propylene glycol is commonly used for astringent, washes one's face
Milk, essence, cleansing product, bath oil, breast of washing one's hands, shampoo, hair care breast, moisturizer, facial film, ointment etc., are one at room temperature
Plant polyalcohols that are transparent, colourless, being dissolved completely in water, there is stickiness and hygroscopic straight-chain fatty alcohol liquid.In application,
Different according to PG concentration, mainly as plasticiser, solvent, water absorption Humectant, preservative, permeation-promoter and cutin softening lytic agent
Use.Butanediol is very common in cosmetics, is one kind of polyhydric alcohol, often does wetting agent and solvent uses in cosmetics,
Moisturizing aspect, because butanediol is small molecule moisturizing composition, so grabbing water ratio very little, also has certain bacteriostasis simultaneously.
Preferably, described cosmetics also include the adjuvant of 0.5～25 weight portion, and the adjuvant in described cosmetics is except combination
The all substances of beyond the region of objective existence.
It is highly preferred that described adjuvant is 1～20 weight portion；It is highly preferred that described adjuvant is 1～15 weight portion.
Preferably, described adjuvant is the adjuvant meeting specific product requirement.Adjuvant is safely and effectively adjuvant, is to meet tool
The product of body and its adjunct ingredient of dosage form requirement, described product includes medicine, cosmetics and personal care product, described
Adjuvant can for the mixture (plus) of Bis(hydroxymethyl)imidazolidinyl urea and iodine propilolic alcohol butyl mephenesin Carbamate, phenoxyethanol and
The mixture (pe-9010) of Sensiva SC50, polyacrylate cross linked polymer (zen), disodiumedetate (edta
～2na), allantoin, glycerol, levan, cetearyl alcohol, polydimethylsiloxane, Jojoba oil, glycerol caprylate, capric acid
At least one in ester, vitamin e.The dosage form of described compositionss can be selected from according to specific product, purposes and usage: makes up
Water, emulsion, cream, gel, facial film, liniment, lotion, spray, soap agent, ointment, tincture, capsule, powder, granule
The napkin of agent, tablet and any group of compound with the present invention.
Preferably, described cosmetics also include water, and described water is purified water or deionized water.
Additionally, a kind of the invention also discloses application in cosmetics, medicine or nursing product for described compositionss.
With respect to prior art, the invention has the benefit that
The present invention starts with from the feature of skin and demand, using the skin protection scheme of science, there is provided a kind of natural origin
There are moisturizing, the multifunctional compositions of whitening skin lightening, described compositionss are made up of natural plant extracts, gently stingless
Swash, and there is instant moisturizing, long-acting moisturizing, promote collagen protein between Skin Cell newborn, promote wound repair, reduce black
The content of element and red pigment is thus reach the effect of skin lightening.
Brief description
Fig. 1 is the measurement result figure in different time to subjects skin's moisture；Wherein, a is commercially available cosmetic water 1
Number；B is that skin lightening water is repaired in the moisturizing in the specific embodiment of the invention 11；C is commercially available cosmetic water 2；
Fig. 2 is the content of melanin and blood red pigment and time chart in experimenter's buccal；
Fig. 3 is experimenter in the whitening effect appraisal result figure using moisture retention water different time of the present invention.
Specific embodiment
For better illustrating the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention
It is described further.
Each component used by following examples is market and buys acquisition, and wherein Fructus Melo berry extract, Wild soybean seed extracts
Thing, Corallium Japonicum Kishinouye algae extract, Flos Matricariae chamomillae flower extract, Herba Centellae extract, glycoprotein obtain in refined purchase of bright Ji.
Embodiment 1
A kind of embodiment of the compositionss with moisturizing and whitening skin lightening of the present invention, combination described in the present embodiment
Thing comprises the component of following weight portion:
1 part of Fructus Melo berry extract, 1.5 parts of Wild soybean seed extract, 2 parts of Corallium Japonicum Kishinouye algae extract.
A kind of cosmetics, except comprising combinations thereof beyond the region of objective existence, also comprise wetting agent: 3 parts of propylene glycol, 2 parts of butanediol, adjuvant:
0.3 part of plus, 0.2 part of pe-9010.
Embodiment 2
A kind of embodiment of the compositionss with moisturizing and whitening skin lightening of the present invention, combination described in the present embodiment
Thing comprises the component of following weight portion:
2.5 parts of Fructus Melo berry extract, 1 part of Wild soybean seed extract, 1 part of Corallium Japonicum Kishinouye algae extract.
A kind of cosmetics, except comprising combinations thereof beyond the region of objective existence, also comprise wetting agent: 4 parts of propylene glycol, 1 part of butanediol, adjuvant:
0.25 part of zen, 0.1 part of xanthan gum, 0.03 part of edta～2na, 0.2 part of allantoin, 2.87 parts of glycerol, 3 parts of levan, hydrogenation
1 part of lecithin, 2 parts of cetearyl glucoside, 1.5 parts of cetearyl alcohol, 3 parts of polydimethylsiloxane, isononyl isononanoate 3
Part, 3 parts of glycerol caprylate, 2 parts of ring five dimethyl silicone polymer, 2 parts of Dimethicone Crosspolymer, vitamin e
0.5 part, 0.3 part of plus, 0.25 part of pe-9010.
Embodiment 3
A kind of embodiment of the compositionss with moisturizing and whitening skin lightening of the present invention, combination described in the present embodiment
Thing comprises the component of following weight portion:
0.5 part of Fructus Melo berry extract, 3 parts of Wild soybean seed extract, 2.5 parts of Corallium Japonicum Kishinouye algae extract, Herba Centellae extract 0.3
Part.
A kind of cosmetics, except comprising combinations thereof beyond the region of objective existence, also comprise wetting agent: 1 part of propylene glycol, 4 parts of butanediol, adjuvant:
0.3 part of plus, 0.25 part of pe-9010,0.2 part of allantoin, 0.25 part of polyacrylate cross linked polymer (zen).
Embodiment 4
A kind of embodiment of the compositionss with moisturizing and whitening skin lightening of the present invention, combination described in the present embodiment
Thing comprises the component of following weight portion:
3 parts of Fructus Melo berry extract, 3 parts of Wild soybean seed extract, 3 parts of Corallium Japonicum Kishinouye algae extract, 1 part of Herba Centellae extract, female
2.5 parts of Flos Chrysanthemi extract.
A kind of cosmetics, except comprising combinations thereof beyond the region of objective existence, also comprise wetting agent: 2 parts of propylene glycol, 3 parts of butanediol, adjuvant:
0.25 part of zen, 0.1 part of xanthan gum, 0.03 part of edta～2na, 0.2 part of allantoin, 2.87 parts of glycerol, 3 parts of levan, hydrogenation
1 part of lecithin, 1.5 parts of cetearyl alcohol, 3 parts of isononyl isononanoate, 3 parts of glycerol caprylate, ring five dimethyl silicone polymer 2
Part, 2 parts of Dimethicone Crosspolymer, 0.5 part of vitamin e, 0.3 part of plus, 0.25 part of pe-9010.
Embodiment 5
A kind of embodiment of the compositionss with moisturizing and whitening skin lightening of the present invention, combination described in the present embodiment
Thing comprises the component of following weight portion:
2.5 parts of Fructus Melo berry extract, 1 part of Wild soybean seed extract, 1 part of Corallium Japonicum Kishinouye algae extract, Flos Matricariae chamomillae flower extract 2.7
Part, 0.1 part of glycoprotein.
A kind of cosmetics, except comprising combinations thereof beyond the region of objective existence, also comprise wetting agent: 2 parts of propylene glycol, 2.5 parts of butanediol, auxiliary
Material: 0.3 part of plus, 0.25 part of pe-9010,0.2 part of allantoin, 0.25 part of polyacrylate cross linked polymer (zen).
Embodiment 6
A kind of embodiment of the compositionss with moisturizing and whitening skin lightening of the present invention, combination described in the present embodiment
Thing comprises the component of following weight portion:
2.5 parts of Fructus Melo berry extract, 1 part of Wild soybean seed extract, 1 part of Corallium Japonicum Kishinouye algae extract, Herba Centellae extract 0.8
Part, 0.3 part of glycoprotein.
A kind of cosmetics, except comprising combinations thereof beyond the region of objective existence, also comprise wetting agent: 2 parts of propylene glycol, 8 parts of butanediol, adjuvant:
0.25 part of zen, 0.1 part of xanthan gum, 0.03 part of edta～2na, 0.2 part of allantoin, 2.87 parts of glycerol, 3 parts of levan, hydrogenation
1 part of lecithin, 2 parts of cetearyl glucoside, 1.5 parts of cetearyl alcohol, 3 parts of polydimethylsiloxane, vitamin e 0.5
Part, 0.3 part of plus, 0.25 part of pe-9010..
Embodiment 7
A kind of embodiment of the compositionss with moisturizing and whitening skin lightening of the present invention, combination described in the present embodiment
Thing comprises the component of following weight portion:
2.5 parts of Fructus Melo berry extract, 1 part of Wild soybean seed extract, 1 part of Corallium Japonicum Kishinouye algae extract, Flos Matricariae chamomillae flower extract 2.5
Part, 1 part of Herba Centellae extract, 0.1 part of glycoprotein.
A kind of cosmetics, except comprising combinations thereof beyond the region of objective existence, also comprise wetting agent: 8 parts of propylene glycol, 2 parts of butanediol, adjuvant:
0.3 part of plus, 0.25 part of pe-9010,0.2 part of allantoin, 0.25 part of polyacrylate cross linked polymer (zen).
Embodiment 8
A kind of embodiment of the compositionss with moisturizing and whitening skin lightening of the present invention, combination described in the present embodiment
Thing comprises the component of following weight portion:
1.5 parts of Fructus Melo berry extract, 0.5 part of Wild soybean seed extract, 0.5 part of Corallium Japonicum Kishinouye algae extract, Flos Matricariae chamomillae flower extract
0.3 part, 1.5 parts of Herba Centellae extract, 0.5 part of glycoprotein.
A kind of cosmetics, except comprising combinations thereof beyond the region of objective existence, also comprise wetting agent: 5 parts of propylene glycol, 1 part of butanediol, adjuvant:
0.25 part of zen, 0.1 part of xanthan gum, 0.03 part of edta～2na, 0.2 part of allantoin, 2.87 parts of glycerol, 3 parts of levan, hydrogenation
1 part of lecithin, 2 parts of cetearyl glucoside, 1.5 parts of cetearyl alcohol, 3 parts of polydimethylsiloxane, vitamin e 0.5
Part, 0.3 part of plus, 0.25 part of pe-9010.
Embodiment 9
A kind of embodiment of the compositionss with moisturizing and whitening skin lightening of the present invention, combination described in the present embodiment
Thing comprises the component of following weight portion:
3 parts of Fructus Melo berry extract, 2 parts of Wild soybean seed extract, 2 parts of Corallium Japonicum Kishinouye algae extract, 3 parts of Flos Matricariae chamomillae flower extract, long-pending
Careless 2 parts of the extract of snow, 3 parts of glycoprotein.
A kind of cosmetics, except comprising combinations thereof beyond the region of objective existence, also comprise wetting agent: 1 part of propylene glycol, 5 parts of butanediol.
Embodiment 10
A kind of embodiment of the compositionss with moisturizing and whitening skin lightening of the present invention, combination described in the present embodiment
Thing comprises the component of following weight portion:
2 parts of Fructus Melo berry extract, 2.5 parts of Wild soybean seed extract, 1.5 parts of Corallium Japonicum Kishinouye algae extract, Flos Matricariae chamomillae flower extract 2
Part, 3 parts of Herba Centellae extract, 1.5 parts of glycoprotein.
A kind of cosmetics, except comprising combinations thereof beyond the region of objective existence, also comprise wetting agent: 4 parts of propylene glycol, 1 part of butanediol, adjuvant:
0.25 part of zen, 0.1 part of xanthan gum, 0.03 part of edta～2na, 0.2 part of allantoin, 2.87 parts of glycerol, cetearyl glucose
2 parts of glycosides, 1.5 parts of cetearyl alcohol, 0.5 part of vitamin e, 0.3 part of plus, 0.25 part of pe-9010.
Embodiment 11
A kind of embodiment of cosmetics of the present invention, cosmetics described in the present embodiment are that skin lightening water is repaired in a moisturizing,
Formula is as follows:
Technique: deionized water, propylene glycol, butanediol are heated to 85 DEG C, are incubated 5 minutes, are cooled to 45 DEG C, add clout
Mix homogeneously.
Embodiment 12
A kind of embodiment of cosmetics of the present invention, cosmetics described in the present embodiment are that skin lightening essence is repaired in a moisturizing
China, formula is as follows:
Remarks: above-mentioned raw materials all can be bought in market and obtain, wherein zen is the polyacrylate cross linked polymer of match Bick
～6
Technique: zen, edta～2na, allantoin, glycerol, levan, propylene glycol, butanediol are added in deionized water,
It is heated to 85 DEG C to dissolving completely, be incubated 5 minutes, be cooled to 45 DEG C, add clout mix homogeneously.
Embodiment 13
A kind of embodiment of cosmetics of the present invention, cosmetics described in the present embodiment are that skin lightening breast is repaired in a moisturizing
Liquid, formula is as follows:
Remarks: gtcc is caprylic/capric triglyceride.
Technique: by aqueous phase: zen, edta～2na, allantoin, glycerol, levan propylene glycol, butanediol add deionized water
In, it is heated to 85 DEG C to dissolving completely；By oil phase: polysorbate～60, peg～60 Span60, spermaceti
Stearyl alcohol, Jojoba oil, polydimethylsiloxane, glycerol caprylate/decanoin, vitamin e are heated to 85 DEG C to dissolving completely,
Oil phase is added aqueous phase homogenizing 4 minutes, insulation emulsifying 5 minutes, stirring is cooled to 45 DEG C, adds clout mix homogeneously.
Embodiment 14
A kind of embodiment of cosmetics of the present invention, cosmetics described in the present embodiment are that brightening cream is repaired in a moisturizing,
Formula is as follows:
Technique: by aqueous phase: zen, edta～2na, allantoin, glycerol, levan, xanthan gum propylene glycol, butanediol add
In deionized water, it is heated to 85 DEG C to dissolving completely, by oil phase: hydrolecithin, cetearyl alcohol, cetearyl glucose
Glycosides, polydimethylsiloxane, isononyl isononanoate, glycerol caprylate/decanoin, ring five dimethyl silicone polymer, poly dimethyl
Dimethicone Crosspolymer, vitamin e are heated to 85 DEG C to dissolving completely, oil phase is added aqueous phase homogenizing 4 minutes, is incubated emulsifying
5 minutes, stirring was cooled to 45 DEG C, added clout mix homogeneously.
Embodiment 15
To embodiment 11, preparation-obtained cosmetics carry out moistening effect test, wherein
Test instrunment: moisture of skin tester, German ck company corneometer cm825；
Test philosophy: measure the moisture of human skin keratinocyte's layer using capacitance algoscopy, its principle is based on water
Notable with the difference in dielectric constant of other materials, different according to moisture content of skin, the capacitance measuring skin is different, thus can
The moisture of the skin to survey；
Test environment: 18 DEG C of keeping temperature, humidity 45% ± 1%；
Prepare before test: any product (cosmetics and topical drug) can not be used within 2～3 days before recipient site, before test,
Experimenter needs the double inboard arm of cleaning, uses face-cloth wiped clean.After cleaning, carry out measurement zone in experimenter's both hands inner forearm
Field mark, before official testing, sits quietly in standard compliant room at least 30 minutes and can not drink water, and forearm exposes, in test shape
State is placed, and keeps easily；
Testing procedure: in experiment, tested products applying amount is 2mg/cm2, it is coated on 2cm2Region, between region be spaced
At least 2cm, selects a region to make blank, selects different time, measures the changing value of each test point, every test three respectively
Secondary, average；Each meansigma methods putting the detection of each period is deducted the numerical value of each blank spot, be this portion of this period
The measured value of position, result represents with humidity measurements, its numerical value is higher then it represents that the moisture-retention function of skin of product is better.
(1) determination of moisture of skin
20 healthy volunteers smear respectively commercially available cosmetic water 1 (porcelain flesh Flos Rosae Rugosae cosmetic water, net purchase price: 78 yuan,
100ml, include Flos Rosae Rugosae extract, ceramide, hyaluronate sodium, glycerol, declare the work(with moisturizing, moisturizing, skin care
Effect), (hundred tender times of passeris montani saturati antelope water are now full of essence lotion to commercially available cosmetic water 2, net purchase price: 67.9 yuan, 100ml, include Herba Leonuri and carry
Take thing, Radix Ophiopogoniss flower extract, Radix Rhodiolae extract, declare that there is moisturizing, moisturizing, bright color), the present invention specifically real
Apply the moisturizing in example 11 and repair skin lightening water continuously using seven days, measure experimenter's moisture content of skin of 1 hour and 8 hours respectively,
Calculate the moisture average of skin, test result is as shown in Figure of description 1:
As shown in Figure 1, smear respectively containing commercially available cosmetic water 1, commercially available cosmetic water 2, the specific embodiment of the invention 11
In moisturizing repair skin lightening water and all show obvious moisture-keeping function after 1 hour, and moistening effect is suitable；After 8 hours, commercially available refreshing
The skin moisture content of skin water 1 and commercially available cosmetic water 2 returns to the normal value of skin, not Hydrolyzed Protein effect, and the present invention
Water in specific embodiment still has obvious moisture-keeping function, and this explanation moisturizing of the present invention is repaired skin lightening water and continued moistening effect
Good.
(2) moistening effect sensory evaluation
50 healthy volunteers smear commercially available cosmetic water 1, commercially available cosmetic water 2, the specific embodiment of the invention 11 respectively
In moisturizing repair that skin lightening water is continuous to be used seven days, measure experimenter respectively in the sense organ to different moisture retention waters using different time
Evaluate, test result is as shown in table 1:
The sensory evaluation to different moisture retention waters for table 1 experimenter
Evaluation criteria: do not think and be dried 8～10 points
Slightly feel to be dried 6～8 points
Feel to be dried 4～6 points
It is dried 2～4 points
As shown in Table 1, the data of the sensory evaluation of volunteer and above-mentioned Instrument measuring has concordance, further illustrate by
The moisturizing that the present composition prepares is repaired skin lightening water and is had long-acting moisture retention.
Embodiment 16
To embodiment 11, preparation-obtained cosmetics carry out whitening skin lightening result test, wherein
Test instrunment: dermal melanin and haemachrome analyzer, German ck company mexameter mx18；
Test philosophy: based on Spectrum Absorption Principle (rgb), after being impinged upon on human body skin by the light of mensure specific wavelength
Volume reflection is determining the content of melanin and blood red pigment in skin；The light irradiation of three kinds of wavelength launched by the emitter of instrument probe
The light of the skin reflex surveyed in skin surface, accepter, because the amount of launching light is certain, therefore just can measure skin and inhale
The amount of the light received, thus the content of the dermal melanin surveyed and blood red pigment.
(1) whitening effect test
Skin lightening water is repaired in the moisturizing that 30 volunteers smear in the specific embodiment of the invention 11, measures respectively using front and even
Continuous using 3 days, 7 days, 14 days, 28 days melanin content in cheek and blood red pigment contents below, calculate meansigma methodss such as table 2 and say
Shown in bright book accompanying drawing 2:
Table 2 experimenter is repairing the melanin of skin lightening water different time, blood red pigment meansigma methodss using moisturizing of the present invention
| Using front | 3 days | 7 days | 14 days | 28 days | |
| Melanin content | 195.1 | 186.7 | 171.3 | 163.2 | 161.7 |
| Content of hemachrome | 298.4 | 289.4 | 269.1 | 249.5 | 245.6 |
From table 2 and Fig. 2, experimenter is repairing melanin and blood in the 3rd day buccal of skin lightening water using moisturizing of the present invention
Red pigment has reduced, and the 7th day melanin and blood red have necessarily are reduced, and the 14th day melanin and blood red hypopigmentation are bright
Show, gradually region is steady for the 28th day melanin and blood red pigment.So skin lightening water is repaired in the moisturizing of the specific embodiment of the invention 11
Begin with whitening effect within 7th day, after the 14th day, whitening effect tends towards stability.
(2) whitening effect visual assessment
Skin lightening water is repaired in the moisturizing that 30 volunteers smear in the specific embodiment of the invention 11, irradiates light on four sides
Room in, by same dermatologist estimate respectively using front and continuous use 3 days, 7 days, 14 days, 28 days, 2 months,
Whitening effect after 4 months, and scored, appraisal result is as shown in Figure of description 3:
Standards of grading: 5～7 points of skin original state
Somewhat effective 3～5 points
1～3 point of significant effective
Continuously repair skin lightening water using the moisturizing of specific embodiment 11 as shown in Figure 3, certain whitening can be estimated within 7 days
Effect；After continuously using 2 weeks, whitening effect is obvious；Continuously tended to be steady using whitening effect after January.
Embodiment 15～16 is repaired skin lightening water only for moisturizing described in embodiment 11 and has been carried out the survey of moisturizing whitening skin lightening result
Examination research, the moisturizing whitening skin lightening result testing research of cosmetics described in embodiment 12～14 is similar to it, and here is no longer detailed
Analysis narration.
Last should be noted that above example is only in order to illustrate technical scheme rather than to present invention guarantor
The restriction of shield scope, although being explained in detail to the present invention with reference to preferred embodiment, those of ordinary skill in the art should
Understand, technical scheme can be modified or equivalent, without deviating from the essence of technical solution of the present invention
And scope.
Claims (10)
1. a kind of compositionss with moisturizing and whitening skin lightening it is characterised in that in parts by weight, including following components:
0.5～3 part of Fructus Melo berry extract, 0.5～3 part of Wild soybean seed extract, 0.5～3 part of Corallium Japonicum Kishinouye algae extract.
2. there are the compositionss of moisturizing and whitening skin lightening as claimed in claim 1 it is characterised in that described compositionss are also wrapped
Include Flos Matricariae chamomillae flower extract and/or Herba Centellae extract, described Flos Matricariae chamomillae flower extract is 0.3～3 weight portion, described Herba Centellae is extracted
Thing is 0.3～3 weight portion.
3. there are the compositionss of moisturizing and whitening skin lightening as claimed in claim 2 it is characterised in that described compositionss are also wrapped
Containing glycoprotein.
4. there are the compositionss of moisturizing and whitening skin lightening as claimed in claim 3 it is characterised in that described glycoprotein is
0.5～3 weight portion.
5. a kind of containing the cosmetics of compositionss, medicine or nursing product as described in any one of Claims 1 to 4.
6. it is characterised in that described cosmetics also include wetting agent, described wetting agent is 2 to cosmetics as claimed in claim 5
～16 weight portions.
7. cosmetics as claimed in claim 6 are it is characterised in that described wetting agent includes 1～8 parts by weight of propylene glycol and 1～8
Weight portion butanediol.
8. the cosmetics as described in claim 5～7 are it is characterised in that described cosmetics also include the auxiliary of 0.5～25 weight portion
Material.
9. cosmetics as claimed in claim 8 are it is characterised in that described adjuvant is 1～20 weight portion；Preferably, described auxiliary
Expect for 1～15 weight portion.
10. application in cosmetics, medicine or nursing product for the compositionss as described in a kind of any one as Claims 1 to 4.
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| CN201610750966.6A CN106333886B (en) | 2016-08-29 | 2016-08-29 | Composition with moisturizing, whitening and skin-brightening effects and application thereof |
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Cited By (3)
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| CN107998017A (en) * | 2017-12-11 | 2018-05-08 | 广州赛莱拉干细胞科技股份有限公司 | A kind of anti-wrinkle containing Flos Osmanthi Fragrantis extract, cosmetic composition and preparation method thereof |
| CN108014040A (en) * | 2017-11-24 | 2018-05-11 | 广州赛莱拉干细胞科技股份有限公司 | Face guard frost and face guard frost applicator system containing coral algae extract |
| CN108272739A (en) * | 2018-04-23 | 2018-07-13 | 广州赛莱拉干细胞科技股份有限公司 | Composition containing dulse extract and its cosmetics |
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| CN108272739A (en) * | 2018-04-23 | 2018-07-13 | 广州赛莱拉干细胞科技股份有限公司 | Composition containing dulse extract and its cosmetics |
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| CN106333886B (en) | 2020-06-02 |
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