CN106310008A

CN106310008A - Traditional Chinese medicine composition for treating allergic rhinitis and preparation method thereof

Info

Publication number: CN106310008A
Application number: CN201610285777.6A
Authority: CN
Inventors: 张道华
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-05-03
Filing date: 2016-05-03
Publication date: 2017-01-11

Abstract

The invention aims to provide a traditional Chinese medicine composition for treating allergic rhinitis, which comprises the following components in parts by weight: 15-30 parts of magnolia liliflora flowers, 5-15 parts of ephedra sinica and/or ephedra intermedia, 10-30 parts of xanthium sorbifolia, 5-15 parts of asarum sieboldii, 5-20 parts of coix lacryma-jobi seeds, 5-20 parts of astragalus membranaceus roots, 5-20 parts of saposhnikovia divaricata roots, 5-20 parts of schizonepeta tenuifolia, 5-20 parts of liquidambar formoana fruits, 5-20 parts of gleditsia sinensis spines, 5-20 parts of heleocharis dulcis herbs, 5-20 parts of platycladus orientalis, 5-20 parts of acacia catechu, 15-30 parts of residue-removed honeycomb extract, 15-30 parts of cirsium japonicum roots, 5-15 parts of angelica dahurica roots, 5-15 parts of poncirus trifoliata and/or citrus aurantium, 5-15 parts of ox horns, 5-15 parts of Chinese gentian roots, 5-15 parts of atractylodes macrocephala, 5-20 parts of ligusticum sinense and/or ligusticum jeholense, 5-20 parts of rhizoma cimicifugae, 5-20 parts of ligusticum chuanxiong, 5-20 parts of akebia trifoliata and/or akebia quinata stems, 5-20 parts of notopterygium sp. rhizomes or roots, 5-20 parts of mulberry leaves, 5-20 parts of lycium barbarum roots, 5-20 parts of andrographis paniculata herbs, and 5-20 parts of polygonum cuspidatum. The invention also provides a preparation method of the traditional Chinese medicine composition.

Description

A kind of Chinese medicine composition treating allergic rhinitis and preparation method

Technical field

The present invention relates to a kind of Chinese medicine preparation, a kind of Chinese medicine composition treating allergic rhinitis and preparation method thereof.

Background technology

Allergic rhinitis is day by day serious along with China's air pollution in recent years, has had changed into serious groupment disease, to people The routine work life of people masses creates very adverse influence, and the simple Therapeutic Method of current allergic rhinitis is only taken de- Sensitizing drug, but common drug desensitization such as hismanal effect is limited, and the drowsiness of chlorphenamine class medicine waits side effect obvious, other west Doctor's the most useful hormone medicine of therapeutic modality, the cost alleviating constitutional symptoms for the moment is that body produces permanent damage, and desensitization Therapeutic Method, i.e. finds out anaphylactogen by the complicated test of some months, then in the way of the subcutaneous injection minute amounts of allergen of several years Realizing repellence desensitization, this treatment is wasted time and energy very much, and once stops treatment, the most likely recurs, and input and output are non- Often it is not directly proportional.

Long-term taking Western medicine also can produce everybody additional disease, owing to various factors affects, occur after western medical treatment nausea and vomiting, The patient of the gastrointestinal dysfunctions such as abdominal pain and distension increases increasingly.A lot of people can produce various bad after long-term taking Western medicine antiallergic Symptom, such as irritable bowel syndrome, gastrointestinal dysfunction.At present, the pathogenesis of allergic rhinitis and associated conditions thereof is the completeest All clear Chu, owing to pathogenesis is complicated, western medicine side effect is stronger, it is impossible to fully meet the needs of extensive patients.And the traditional Chinese medical science Medicine is from organic conception, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, and certainly, side effect is little, treatment cost economy, has good development prospect for curative effect.

Long-term taking Western medicine can produce irritability stasis at present, the situations such as Rong Wei is obstructed.Having research data to confirm, Chinese medicine can not only be controlled Treat and improve gastropathy, strengthen the metabolic capacity of health, and while treatment, moreover it is possible to disorderly digestive function is adjusted, Treatment can be cured for a long time, and relapse rate is low.

Summary of the invention

The present invention mainly solves the various side effect of western medicine in the presence of prior art and the technical problem of limitation, thus carries It is specifically designed for, for a kind of, the Chinese medicine composition that allergic rhinitis carries out treating, is aided with Recent study simultaneously and shows there is significant curative effect Special medicinal material, and the Chinese medicine composition allocated.Said composition can either be individually used for treatment, it is also possible to controls coordinating Western medicine During treatment, alleviate and remove the side effect that patient body is caused by Western medicine.

The above-mentioned technical problem of the present invention is mainly addressed by following technical proposals:

A kind of Chinese medicine composition treating allergic rhinitis, it is characterised in that: described Chinese medicine composition is by following weight parts proportioning Each component form: Flos Magnoliae 15-30 part, Herba Ephedrae 5-15 part, Fructus Xanthii 10-30 part, Herba Asari 5-15 part, thatch core 5-20 part, Radix Astragali 5-20 part, Radix Saposhnikoviae 5-20 part, Herba Schizonepetae 5-20 part, Fructus Liquidambaris 5-20 part, Spina Gleditsiae 5-20 part, Herba Eleocharitis 5-20 part, Cortex Phellodendri 5-20 part, Catechu 5-20 part, Nidus Vespae slagging-off extract 15-30 part, fresh cirsii japonici,radix 15-30 part, Radix Angelicae Dahuricae 5-15 Part, Fructus Aurantii 5-15 part, Cornu Bovis seu Bubali 5-15 part, Radix Gentianae 5-15 part, Rhizoma Atractylodis Macrocephalae 5-15 part, Rhizoma Ligustici 5-20 part, Rhizoma Cimicifugae 5-20 Part, Rhizoma Chuanxiong 5-20 part, Caulis Akebiae 5-20 part, Rhizoma Et Radix Notopterygii 5-20 part, Folium Mori 5-20 part, fresh fructus lycii root 5-20 part, Herba Andrographis 5-20 Part, Rhizoma Polygoni Cuspidati 5-20 part.

Further, aforementioned Chinese medicine composition is made up of each component of following weight parts proportioning: Flos Magnoliae 20-30 part, Herba Ephedrae 9-15 Part, Fructus Xanthii 15-30 part, Herba Asari 12-15 part, thatch core 10-20 part, Radix Astragali 10-20 part, Radix Saposhnikoviae 10-20 part, Herba Schizonepetae 10-20 Part, Fructus Liquidambaris 10-20 part, Spina Gleditsiae 10-20 part, Herba Eleocharitis 10-20 part, Cortex Phellodendri 10-20 part, Catechu 10-20 part, Nidus Vespae slagging-off extract 20-30 part, fresh cirsii japonici,radix 20-30 part, Radix Angelicae Dahuricae 10-15 part, Fructus Aurantii 10-15 part, Cornu Bovis seu Bubali 10-15 part, Radix Gentianae 10-15 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Rhizoma Ligustici 10-20 part, Rhizoma Cimicifugae 10-20 part, Rhizoma Chuanxiong 10-20 part, Caulis Akebiae 10-20 Part, Rhizoma Et Radix Notopterygii 10-20 part, Folium Mori 10-20 part, fresh fructus lycii root 10-20 part, Herba Andrographis 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part.

Further, aforementioned Chinese medicine composition is made up of each component of following weight parts proportioning: Flos Magnoliae 22 parts, 11 parts of Herba Ephedrae, Fructus Xanthii 23 parts, Herba Asari 14 parts, thatch core 12 parts, Radix Astragali 12 parts, Radix Saposhnikoviae 12 parts, Herba Schizonepetae 12 parts, Fructus Liquidambaris 12 parts, Spina Gleditsiae 12 parts, Herba Eleocharitis 15 parts, Cortex Phellodendri 14 parts, Catechu 13 parts, Nidus Vespae slagging-off extract 25 parts, fresh cirsii japonici,radix 25 parts, the Radix Angelicae Dahuricae 12 parts, Fructus Aurantii 14 parts, 12 parts of Cornu Bovis seu Bubali, Radix Gentianae 12 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, Rhizoma Ligustici 16 parts, Rhizoma Cimicifugae 18 Part, Rhizoma Chuanxiong 16 parts, Caulis Akebiae 18 parts, Rhizoma Et Radix Notopterygii 18 parts, 16 parts of Folium Mori, fresh fructus lycii root 18 parts, Herba Andrographis 18 parts, Rhizoma Polygoni Cuspidati 18 parts, or, be made up of each component of following weight parts proportioning, Flos Magnoliae 26 parts, 12 parts of Herba Ephedrae, Fructus Xanthii 24 parts, Herba Asari 15 parts, thatch core 20 parts, Radix Astragali 20 parts, Radix Saposhnikoviae 18 parts, Herba Schizonepetae 18 parts, Fructus Liquidambaris 16 parts, Spina Gleditsiae 16 parts, logical It grass 20 parts, Cortex Phellodendri 20 parts, Catechu 20 parts, Nidus Vespae slagging-off extract 30 parts, fresh cirsii japonici,radix 30 parts, the Radix Angelicae Dahuricae 15 Part, Fructus Aurantii 15 parts, 15 parts of Cornu Bovis seu Bubali, Radix Gentianae 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Rhizoma Ligustici 18 parts, Rhizoma Cimicifugae 10 parts, Rhizoma Chuanxiong 10 parts, Caulis Akebiae 10 parts, Rhizoma Et Radix Notopterygii 10 parts, 15 parts of Folium Mori, fresh fructus lycii root 15 parts, Herba Andrographis 15 parts, Rhizoma Polygoni Cuspidati 15 parts.

The preparation method of a kind of Chinese medicine composition treating allergic rhinitis, it is characterised in that choose certain weight portion foregoing The traditional Chinese medicine composite of proportioning, and follow the steps below and be prepared from.

1) processing of medical material step: calcine: Rhizoma Ligustici, Rhizoma Cimicifugae, Rhizoma Chuanxiong, Caulis Akebiae, with heatproof container fire-bar under 100 DEG C Part lower open mouth calcine, pulverizes standby；Processed with vinegar: take the fresh cirsii japonici,radix totally dried, according to stir-baking with vinegar fried dry, smashs to pieces standby；Parch: The Radix Angelicae Dahuricae, Fructus Aurantii, Cornu Bovis seu Bubali, the Rhizoma Atractylodis Macrocephalae, Rhizoma Et Radix Notopterygii, Rhizoma Polygoni Cuspidati clean rear parch, pulverize；Chopping: by Flos Magnoliae, Fructus Xanthii, exceedingly high Grass, Radix Gentianae, Folium Mori, fresh fructus lycii root, Herba Andrographis, remove undesirable root and impurity, picks clean impurity, the destemming leaf that takes, and sieve dedusting is considered to be worth doing, Clean chopping, cross 100-200 mesh sieve；Processed with honey: Herba Ephedrae, Herba Asari, Ci Ren, Radix Astragali, Radix Saposhnikoviae, Herba Schizonepetae, Fructus Liquidambaris, Spina Gleditsiae, Cortex Phellodendri, Catechu, take clean medical material shave, add by 1: the mulse after 10-1: 20 dilution proportion mixes, uniformly spread out in baking oven On interior shelf, 70-80 DEG C of heating 10～20min, take out to shakeout and dry.

2) by the calcine of step (1), processed with vinegar, parch, the medical material co-grinding of processed with honey gained, 120-200 mesh sieve is crossed, by weight Amount part mixing, obtains former powder A, and stirs and sterilize 30-60min with ultra violet lamp.

3) by the former powder A after sterilizing, distilled water reflux, extract, containing 50-70% ethanol is added 2-4 time, every time by the second of 3-5 times amount Alcohol reflux extracts 1-1.5 hour, filters united extraction liquid, and reclaims ethanol, is concentrated into relative density 1.1-1.3, adds 75% Appropriate amount of ethanol, makes medicinal liquid alcohol content mass fraction promote 1-2 times, and limit edged is sufficiently stirred for, and stands 12-18h, filters, and reclaims Ethanol to without alcohol taste, obtains clear paste, then adds distilled water extremely containing about crude drug 1-5g/ml, and medicinal liquid adds percentage by weight 1-2% activated carbon, After heated and boiled, cooling, stand at low temperature 6-12h after filtration, obtain water-soluble medicine soup, filter off medicinal residues and obtain alcohol extraction medicinal liquid.

4) the chopping medical material of step (1) is squeezed into juice, and mixes to obtain raw pharmacy liquid, life pharmacy liquid is heated to 65～75 DEG C, And it is cooled to 5-10 DEG C rapidly after keeping this temperature 30-45min, and sterilize in this way, must sterilize raw pharmacy liquid.

5) by raw for the sterilization of step (3) gained aforementioned alcohol extraction medicinal liquid and step (4) gained pharmacy liquid mixing, further mistake filters Removing medicinal residues, slow evaporation concentrates becomes thickness ointment, and Nidus Vespae is carefully removed impurity and useless attachment, is ground into Nidus Vespae slagging-off Extract, mixes with thickness ointment, obtains described Chinese medicine composition.

After raw to aforementioned alcohol extraction medicinal liquid and sterilization pharmacy liquid is mixed by abovementioned steps (5), then carry out multiple times of filtration to remove medicine fully Slag, then carry out multiple times of filtration to remove medicinal residues fully, then be evaporated concentrating, add the cross-linked methyl sodium cellulosate of 3%-10%, Wet granulation, slowly dries, and adds appropriate magnesium stearate to being easy to the dosage of tabletting, is then compressed to tablet, very Carrying out humidity strip under good air flow communication to be dried, be dried 3-7 days at 15-20 DEG C, sampling about 1% determines that tablet is enough It is dried, obtains the Chinese medicine composition tablet made.

Aforesaid Fructus Xanthii and Cortex Phellodendri can first use the Oleum Sesami fried 3-10min of slow fire in aluminum pot before processing.

The processing mode of the former powder A of abovementioned steps (3), can be replaced by following: add medicine gross mass 5-15 times quality Mass concentration is the ethanol water of 65%, is then refluxed for extracting 3 times, each 0.5 hour, and united extraction liquid also cools down 30-60min, then through 3-5 8 layers of filtered through gauze, obtain first-time filtrate.Filtering residue after filtering is merged, adds filtering residue equally The mass concentration of gross mass 5-15 times quality is the ethanol water of 65%, is then refluxed for extracting 3 times, each 0.5 hour, closes And extracting solution cool down 30-60min, then through 2-3 8 layers of filtered through gauze, obtain secondary filtrate, first-time filtrate and secondary are filtered Liquid merges, and decompression recycling ethanol is concentrated into without alcohol taste, then proceeds in evaporating dish, and 60-65 DEG C of heating in water bath is evaporated.

Aforementioned Rhizoma Ligustici, Rhizoma Cimicifugae, Rhizoma Chuanxiong, the calcine step of Caulis Akebiae medical material can be replaced by, and temperature is 100 DEG C～120 DEG C, puts into Vinegar concentration is 1g/100mL～2g/100mL, the calcine time is 1h～3h, the temperature programming time is 15min～60min, medical material Granularity is no thicker than 5cm less than 60 mesh, bedding thickness；Concrete calcine temperature takes 100 DEG C, 105 DEG C, 110 DEG C, and vinegar concentration takes 1.2g/100mL, 1.5g/100mL, 1.8g/100mL, the calcine time takes 1h, 1.5h, 2h, the temperature programming time take 20min, 40min, 60min, medical material granularity 80 mesh, 100 mesh, 120 mesh, bedding thickness is no thicker than 2cm, 3cm, 4cm.

Further, aforementioned after aforementioned fried medicinal liquid and the mixing of raw pharmacy liquid, multiple times of filtration is carried out again to remove medicinal residues fully Step, according to circumstances chooses, if fried medicinal liquid and raw pharmacy liquid are all without any medicinal residues, does not also produce precipitation etc. after mixing, Then without carrying out, if still occurring in that precipitation or floccule, then this step can be carried out.That adds in evaporation and concentration is auxiliary Material is such as common adjuvants such as fructose, crystal sugar, Mel, starch, cyclodextrin.

Detailed description of the invention

Below the preferred embodiments of the present invention are described in detail, so that advantages and features of the invention can be easier to by this area Artisans understand that, thus protection scope of the present invention is made apparent clear and definite defining.

Embodiment 1

A kind of Chinese medicine composition treating allergic rhinitis, it is characterised in that: described Chinese medicine composition is by following weight parts proportioning Each component form: Flos Magnoliae 22 parts, 11 parts of Herba Ephedrae, Fructus Xanthii 23 parts, Herba Asari 14 parts, thatch core 12 parts, Radix Astragali 12 parts, Radix Saposhnikoviae 12 parts, Herba Schizonepetae 12 parts, Fructus Liquidambaris 12 parts, Spina Gleditsiae 12 parts, Herba Eleocharitis 15 parts, Cortex Phellodendri 14 parts, Catechu 13 Part, Nidus Vespae slagging-off extract 25 parts, fresh cirsii japonici,radix 25 parts, the Radix Angelicae Dahuricae 12 parts, Fructus Aurantii 14 parts, 12 parts of Cornu Bovis seu Bubali, Radix Gentianae 12 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, Rhizoma Ligustici 16 parts, Rhizoma Cimicifugae 18 parts, Rhizoma Chuanxiong 16 parts, Caulis Akebiae 18 parts, Rhizoma Et Radix Notopterygii 18 parts, Folium Mori 16 Part, fresh fructus lycii root 18 parts, Herba Andrographis 18 parts, Rhizoma Polygoni Cuspidati 18 parts.

1) processing of medical material step: calcine: Rhizoma Ligustici, Rhizoma Cimicifugae, Rhizoma Chuanxiong, Caulis Akebiae, with heatproof container fire-bar under 100 DEG C Part lower open mouth calcine, pulverizes standby；Processed with vinegar: take the fresh cirsii japonici,radix totally dried, according to stir-baking with vinegar fried dry, smashs to pieces standby；Parch: The Radix Angelicae Dahuricae, Fructus Aurantii, Cornu Bovis seu Bubali, the Rhizoma Atractylodis Macrocephalae, Rhizoma Et Radix Notopterygii, Rhizoma Polygoni Cuspidati clean rear parch, pulverize；Chopping: by Flos Magnoliae, Fructus Xanthii, exceedingly high Grass, Radix Gentianae, Folium Mori, fresh fructus lycii root, Herba Andrographis, remove undesirable root and impurity, picks clean impurity, the destemming leaf that takes, and sieve dedusting is considered to be worth doing, Clean chopping, cross 160 mesh sieves；Processed with honey: Herba Ephedrae, Herba Asari, Ci Ren, Radix Astragali, Radix Saposhnikoviae, Herba Schizonepetae, Fructus Liquidambaris, Spina Gleditsiae, river Cortex Phellodendri, Catechu, take clean medical material shave, and the mulse after adding by 1: 15 dilution proportion mixes, and uniformly spreads out the frame in baking oven On son, 70-75 DEG C of heating 15min, takes out to shakeout and dries.

2) by the calcine of step (1), processed with vinegar, parch, the medical material co-grinding of processed with honey gained, 160 mesh sieves are crossed, by weight Mixing, obtains former powder A, and stirs and sterilize 40min with ultra violet lamp.

3) by the former powder A after sterilizing, distilled water reflux, extract, containing 65% ethanol is added 3 times, every time with the alcohol reflux of 4 times amount Extract 1 hour, filter united extraction liquid, and reclaim ethanol, be concentrated into relative density 1.1-1.2, add 75% appropriate amount of ethanol, Making medicinal liquid alcohol content mass fraction promote 2 times, limit edged is sufficiently stirred for, and stands 15h, filters, and reclaims ethanol to without alcohol taste, Clear paste, then add distilled water to containing about crude drug 3g/ml, medicinal liquid adds percentage by weight 1-2% activated carbon, after heated and boiled, cooling, Stand at low temperature 9h after filtration, obtains water-soluble medicine soup, filters off medicinal residues and obtains alcohol extraction medicinal liquid.

4) the chopping medical material of step (1) is squeezed into juice, and mixes to obtain raw pharmacy liquid, life pharmacy liquid is heated to 65～70 DEG C, And it is cooled to 5-10 DEG C rapidly after keeping this temperature 30min, and sterilize in this way, must sterilize raw pharmacy liquid.

After raw to aforementioned alcohol extraction medicinal liquid and sterilization pharmacy liquid is mixed by abovementioned steps (5), then carry out multiple times of filtration to remove medicine fully Slag, then carry out multiple times of filtration to remove medicinal residues fully, then be evaporated concentrating, add the cross-linked methyl sodium cellulosate of 3%-7%, Wet granulation, slowly dries, and adds appropriate magnesium stearate to being easy to the dosage of tabletting, is then compressed to tablet, very Carrying out humidity strip under good air flow communication to be dried, be dried 3-5 days at 15-20 DEG C, sampling about 1% determines that tablet is enough It is dried, obtains the Chinese medicine composition tablet made.

Embodiment 2

A kind of Chinese medicine composition treating allergic rhinitis, it is characterised in that: described Chinese medicine composition is by following weight parts proportioning Each component form: Flos Magnoliae 26 parts, 12 parts of Herba Ephedrae, Fructus Xanthii 24 parts, Herba Asari 15 parts, thatch core 20 parts, Radix Astragali 20 parts, Radix Saposhnikoviae 18 parts, Herba Schizonepetae 18 parts, Fructus Liquidambaris 16 parts, Spina Gleditsiae 16 parts, Herba Eleocharitis 20 parts, Cortex Phellodendri 20 parts, Catechu 20 Part, Nidus Vespae slagging-off extract 30 parts, fresh cirsii japonici,radix 30 parts, the Radix Angelicae Dahuricae 15 parts, Fructus Aurantii 15 parts, 15 parts of Cornu Bovis seu Bubali, Radix Gentianae 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Rhizoma Ligustici 18 parts, Rhizoma Cimicifugae 10 parts, Rhizoma Chuanxiong 10 parts, Caulis Akebiae 10 parts, Rhizoma Et Radix Notopterygii 10 parts, Folium Mori 15 Part, fresh fructus lycii root 15 parts, Herba Andrographis 15 parts, Rhizoma Polygoni Cuspidati 15 parts.

1) processing of medical material step: calcine: Rhizoma Ligustici, Rhizoma Cimicifugae, Rhizoma Chuanxiong, Caulis Akebiae, with heatproof container fire-bar under 100 DEG C Part lower open mouth calcine, pulverizes standby；Processed with vinegar: take the fresh cirsii japonici,radix totally dried, according to stir-baking with vinegar fried dry, smashs to pieces standby；Parch: The Radix Angelicae Dahuricae, Fructus Aurantii, Cornu Bovis seu Bubali, the Rhizoma Atractylodis Macrocephalae, Rhizoma Et Radix Notopterygii, Rhizoma Polygoni Cuspidati clean rear parch, pulverize；Chopping: by Flos Magnoliae, Fructus Xanthii, exceedingly high Grass, Radix Gentianae, Folium Mori, fresh fructus lycii root, Herba Andrographis, remove undesirable root and impurity, picks clean impurity, the destemming leaf that takes, and sieve dedusting is considered to be worth doing, Clean chopping, cross 180 mesh sieves；Processed with honey: Herba Ephedrae, Herba Asari, Ci Ren, Radix Astragali, Radix Saposhnikoviae, Herba Schizonepetae, Fructus Liquidambaris, Spina Gleditsiae, river Cortex Phellodendri, Catechu, take clean medical material shave, and the mulse after adding by 1: 18 dilution proportion mixes, and uniformly spreads out the frame in baking oven On son, 75-80 DEG C of heating 20min, takes out to shakeout and dries.

2) by the calcine of step (1), processed with vinegar, parch, the medical material co-grinding of processed with honey gained, 180 mesh sieves are crossed, by weight Mixing, obtains former powder A, and stirs and sterilize 50min with ultra violet lamp.

3) by the former powder A after sterilizing, distilled water reflux, extract, containing 70% ethanol is added 4 times, every time with the alcohol reflux of 5 times amount Extract 1.5 hours, filter united extraction liquid, and reclaim ethanol, be concentrated into relative density 1.2-1.3, add 75% appropriate amount of ethanol, Making medicinal liquid alcohol content mass fraction promote 1 times, limit edged is sufficiently stirred for, and stands 18h, filters, and reclaims ethanol to without alcohol taste, Clear paste, then add distilled water to containing about crude drug 4-5g/ml, medicinal liquid adds percentage by weight 1-2% activated carbon, after heated and boiled, cold But, stand at low temperature 12h after filtration, obtain water-soluble medicine soup, filter off medicinal residues and obtain alcohol extraction medicinal liquid.

4) the chopping medical material of step (1) is squeezed into juice, and mixes to obtain raw pharmacy liquid, life pharmacy liquid is heated to 70～75 DEG C, And it is cooled to 5-10 DEG C rapidly after keeping this temperature 45min, and sterilize in this way, must sterilize raw pharmacy liquid.

After raw to aforementioned alcohol extraction medicinal liquid and sterilization pharmacy liquid is mixed by abovementioned steps (5), then carry out multiple times of filtration to remove medicine fully Slag, then carry out multiple times of filtration to remove medicinal residues fully, then be evaporated concentrating, add the cross-linked methyl cellulose of 6%-10% Sodium, wet granulation, slowly dry, add appropriate magnesium stearate to being easy to the dosage of tabletting, be then compressed to tablet, Carrying out humidity strip under extraordinary air flow communication to be dried, be dried 5-7 days at 15-20 DEG C, whether sampling about 1% determines tablet Sufficiently dry, obtains the Chinese medicine composition tablet made.

Embodiment 3,

Consistent with previous embodiment 2, different scheme section is:

Aforesaid Fructus Xanthii and Cortex Phellodendri are the most first with the Oleum Sesami fried 3-5min of slow fire in aluminum pot.

The processing mode of the former powder A of abovementioned steps (3), can be replaced by following: add medicine gross mass 5-10 times quality Mass concentration is the ethanol water of 65%, is then refluxed for extracting 3 times, each 0.5 hour, and united extraction liquid also cools down 30min, Again through 38 layers of filtered through gauze, obtain first-time filtrate.Filtering residue after filtering is merged, same addition filtering residue gross mass 5-15 times The mass concentration of quality is the ethanol water of 65%, is then refluxed for extracting 3 times, each 0.5 hour, and united extraction liquid is the coldest But 30min, then through 38 layers of filtered through gauze, obtain secondary filtrate, first-time filtrate and secondary filtrate are merged, recovered under reduced pressure Ethanol, is concentrated into without alcohol taste, then proceeds in evaporating dish, and 60-65 DEG C of heating in water bath is evaporated.

Aforementioned Rhizoma Ligustici, Rhizoma Cimicifugae, Rhizoma Chuanxiong, the calcine step of Caulis Akebiae medical material can be replaced by, and temperature is 100 DEG C～110 DEG C, puts into Vinegar concentration is 1g/100mL, the calcine time is 1h, the temperature programming time is 30min, medical material granularity is thick less than 60 mesh, place mat Degree no thicker than 5cm；Concrete calcine temperature takes 105 DEG C, and vinegar concentration takes 1.2g/100mL, and the calcine time takes 1h, 1.5h, 2h, The temperature programming time takes 40min, and medical material granularity 100 mesh, bedding thickness is no thicker than 3cm.

The above, the only detailed description of the invention of the present invention, but protection scope of the present invention is not limited thereto, any without Cross change or replacement that creative work is expected, all should contain within protection scope of the present invention.Therefore, the protection of the present invention Scope should be as the criterion with the protection domain that claims are limited.

Claims

1. the Chinese medicine composition treating allergic rhinitis, it is characterised in that: described Chinese medicine composition is each by following weight parts proportioning Component forms:

Flos Magnoliae 15-30 part, Herba Ephedrae 5-15 part, Fructus Xanthii 10-30 part, Herba Asari 5-15 part, thatch core 5-20 part, Radix Astragali 5-20 Part, Radix Saposhnikoviae 5-20 part, Herba Schizonepetae 5-20 part, Fructus Liquidambaris 5-20 part, Spina Gleditsiae 5-20 part, Herba Eleocharitis 5-20 part, Cortex Phellodendri 5-20 Part, Catechu 5-20 part, Nidus Vespae slagging-off extract 15-30 part, fresh cirsii japonici,radix 15-30 part, Radix Angelicae Dahuricae 5-15 part, Fructus Aurantii 5-15 Part, Cornu Bovis seu Bubali 5-15 part, Radix Gentianae 5-15 part, Rhizoma Atractylodis Macrocephalae 5-15 part, Rhizoma Ligustici 5-20 part, Rhizoma Cimicifugae 5-20 part, Rhizoma Chuanxiong 5-20 part, Caulis Akebiae 5-20 part, Rhizoma Et Radix Notopterygii 5-20 part, Folium Mori 5-20 part, fresh fructus lycii root 5-20 part, Herba Andrographis 5-20 part, Rhizoma Polygoni Cuspidati 5-20 part.

A kind of Chinese medicine composition treating allergic rhinitis the most according to claim 1, it is characterised in that: described Chinese medicine composition It is made up of each component of following weight parts proportioning:

Flos Magnoliae 20-30 part, Herba Ephedrae 9-15 part, Fructus Xanthii 15-30 part, Herba Asari 12-15 part, thatch core 10-20 part, Radix Astragali 10-20 Part, Radix Saposhnikoviae 10-20 part, Herba Schizonepetae 10-20 part, Fructus Liquidambaris 10-20 part, Spina Gleditsiae 10-20 part, Herba Eleocharitis 10-20 part, river Huang Cypress 10-20 part, Catechu 10-20 part, Nidus Vespae slagging-off extract 20-30 part, fresh cirsii japonici,radix 20-30 part, Radix Angelicae Dahuricae 10-15 part, Fructus Aurantii 10-15 part, Cornu Bovis seu Bubali 10-15 part, Radix Gentianae 10-15 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Rhizoma Ligustici 10-20 part, Rhizoma Cimicifugae 10-20 Part, Rhizoma Chuanxiong 10-20 part, Caulis Akebiae 10-20 part, Rhizoma Et Radix Notopterygii 10-20 part, Folium Mori 10-20 part, fresh fructus lycii root 10-20 part, punching Lotus 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part.

A kind of Chinese medicine composition treating allergic rhinitis the most according to claim 2, it is characterised in that: described Chinese medicine composition It is made up of each component of following weight parts proportioning:

Flos Magnoliae 22 parts, 11 parts of Herba Ephedrae, Fructus Xanthii 23 parts, Herba Asari 14 parts, thatch core 12 parts, Radix Astragali 12 parts, Radix Saposhnikoviae 12 Part, Herba Schizonepetae 12 parts, Fructus Liquidambaris 12 parts, Spina Gleditsiae 12 parts, Herba Eleocharitis 15 parts, Cortex Phellodendri 14 parts, Catechu 13 parts, honeybee Nest slagging-off extract 25 parts, fresh cirsii japonici,radix 25 parts, the Radix Angelicae Dahuricae 12 parts, Fructus Aurantii 14 parts, 12 parts of Cornu Bovis seu Bubali, Radix Gentianae 12 parts, The Rhizoma Atractylodis Macrocephalae 12 parts, Rhizoma Ligustici 16 parts, Rhizoma Cimicifugae 18 parts, Rhizoma Chuanxiong 16 parts, Caulis Akebiae 18 parts, Rhizoma Et Radix Notopterygii 18 parts, 16 parts of Folium Mori, fresh Chinese holly Qi root 18 parts, Herba Andrographis 18 parts, Rhizoma Polygoni Cuspidati 18 parts.

Flos Magnoliae 26 parts, 12 parts of Herba Ephedrae, Fructus Xanthii 24 parts, Herba Asari 15 parts, thatch core 20 parts, Radix Astragali 20 parts, Radix Saposhnikoviae 18 Part, Herba Schizonepetae 18 parts, Fructus Liquidambaris 16 parts, Spina Gleditsiae 16 parts, Herba Eleocharitis 20 parts, Cortex Phellodendri 20 parts, Catechu 20 parts, honeybee Nest slagging-off extract 30 parts, fresh cirsii japonici,radix 30 parts, the Radix Angelicae Dahuricae 15 parts, Fructus Aurantii 15 parts, 15 parts of Cornu Bovis seu Bubali, Radix Gentianae 15 parts, The Rhizoma Atractylodis Macrocephalae 15 parts, Rhizoma Ligustici 18 parts, Rhizoma Cimicifugae 10 parts, Rhizoma Chuanxiong 10 parts, Caulis Akebiae 10 parts, Rhizoma Et Radix Notopterygii 10 parts, 15 parts of Folium Mori, fresh Chinese holly Qi root 15 parts, Herba Andrographis 15 parts, Rhizoma Polygoni Cuspidati 15 parts.

5. the preparation method of the Chinese medicine composition treating allergic rhinitis, it is characterised in that choose such as the weight of claim 1 or 2 The traditional Chinese medicine composite of amount part proportioning, and follow the steps below and be prepared from:

1) processing of medical material step:

Calcine: Rhizoma Ligustici, Rhizoma Cimicifugae, Rhizoma Chuanxiong, Caulis Akebiae, with heatproof container heating condition lower open mouth calcine under 100 DEG C, pulverizes standby With；

Processed with vinegar: take the fresh cirsii japonici,radix totally dried, according to stir-baking with vinegar fried dry, smashs to pieces standby；

Parch: the Radix Angelicae Dahuricae, Fructus Aurantii, Cornu Bovis seu Bubali, the Rhizoma Atractylodis Macrocephalae, Rhizoma Et Radix Notopterygii, Rhizoma Polygoni Cuspidati clean rear parch, pulverize:

Chopping: by Flos Magnoliae, Fructus Xanthii, Herba Eleocharitis, Radix Gentianae, Folium Mori, fresh fructus lycii root, Herba Andrographis, removes undesirable root and impurity, Pick clean impurity, the destemming leaf that takes, sieve dedusting bits, clean chopping, cross 100-200 mesh sieve；

Processed with honey: Herba Ephedrae, Herba Asari, Ci Ren, Radix Astragali, Radix Saposhnikoviae, Herba Schizonepetae, Fructus Liquidambaris, Spina Gleditsiae, Cortex Phellodendri, Catechu, takes clean medicine Material shave, adds by 1: the mulse after 10-1: 20 dilution proportion mixes, and uniformly spreads out on the shelf in baking oven, 70-80 DEG C of heating 10～20min, take out to shakeout and dry；

2) by the calcine of step (1), processed with vinegar, parch, the medical material co-grinding of processed with honey gained, 120-200 mesh sieve is crossed, by weight Part mixing, obtains former powder A, and stirs and sterilize 30-60min with ultra violet lamp；

3) by the former powder A after sterilizing, distilled water reflux, extract, containing 50-70% ethanol is added 2-4 time, every time with the ethanol of 3-5 times amount Reflux, extract, 1-1.5 hour, filters united extraction liquid, and reclaims ethanol, is concentrated into relative density 1.1-1.3, adds 75% Appropriate amount of ethanol, makes medicinal liquid alcohol content mass fraction promote 1-2 times, and limit edged is sufficiently stirred for, and stands 12-18h, filters, and reclaims Ethanol to without alcohol taste, obtains clear paste, then adds distilled water extremely containing about crude drug 1-5g/ml, and medicinal liquid adds percentage by weight 1-2% activated carbon, After heated and boiled, cooling, stand at low temperature 6-12h after filtration, obtain water-soluble medicine soup, filter off medicinal residues and obtain alcohol extraction medicinal liquid；

4) the chopping medical material of step (1) is squeezed into juice, and mix to obtain raw pharmacy liquid, life pharmacy liquid is heated to 65～75 DEG C, and Being cooled to 5-10 DEG C rapidly after keeping this temperature 30-45min, sterilize in this way, must sterilize raw pharmacy liquid；

5) by raw for the sterilization of step (3) gained aforementioned alcohol extraction medicinal liquid and step (4) gained pharmacy liquid mixing, medicine it is filtered to remove further Slag, slow evaporation concentrates becomes thickness ointment；

Nidus Vespae is carefully removed impurity and useless attachment, be ground into Nidus Vespae slagging-off extract, mix with thickness ointment, obtain described in Drug composition.

6. the preparation method of the Chinese medicine composition of a treatment chronic gastritis as claimed in claim 5, it is characterised in that:

After raw to aforementioned alcohol extraction medicinal liquid and sterilization pharmacy liquid is mixed by described step (5), then carry out multiple times of filtration to remove medicine fully Slag, then carry out multiple times of filtration to remove medicinal residues fully, then be evaporated concentrating, add the cross-linked methyl sodium cellulosate of 3%-10%, Wet granulation, slowly dries, and adds appropriate magnesium stearate to being easy to the dosage of tabletting, is then compressed to tablet, very Carrying out humidity strip under good air flow communication to be dried, be dried 3-7 days at 15-20 DEG C, sampling about 1% determines that tablet is enough It is dried, obtains the Chinese medicine composition tablet made.