CN106267112A

CN106267112A - A kind of medicine treating erosive gastritis

Info

Publication number: CN106267112A
Application number: CN201610868721.3A
Authority: CN
Inventors: 张雷
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-09-30
Filing date: 2016-09-30
Publication date: 2017-01-04

Abstract

The invention discloses a kind of medicine treating erosive gastritis, described medicine is made up of the raw material of following parts by weight: Radix Codonopsis 12 18 parts, the Rhizoma Atractylodis Macrocephalae 7 12 parts, 11 17 parts of Poria, Ramulus Cinnamomi 48 parts, the Radix Paeoniae Alba 10 15 parts, Fructus Amomi 6 11 parts, Radix Et Rhizoma Nardostachyos 8 12 parts, Herba Artemisiae Anomalae 12 18 parts, Os Sepiae 7 13 parts, 8 12 parts of Rhizoma Zingiberis Recens, Rhizoma Corydalis 8 12 parts, Radix Glycyrrhizae Preparata 4 10 parts, 25 pieces of Fructus Jujubae.This Chinese medicine has purging liver-fire, invigorating the spleen and benefiting QI, blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain, and to improve the effect of human metabolism, when erosive gastritis, effect is notable.

Description

A kind of medicine treating erosive gastritis

Technical field

The invention belongs to technical field of Chinese medicines, be specifically related to a kind of medicine treating erosive gastritis.

Background technology

Erosive gastritis, also known as gastritis verrucosa or varioliform gastritis, there is multiple excipuliforms, the folded shape that expands in Stomach in Patients mucosa Or pimple sample protuberance, diameter 5～10mm, mucomembranous defect seen from top or umbilicus sample depression, there is erosion at center, and protuberance is the most without red Dizzy, but it is often accompanied by the erythema that size is similar, common with gastric antrum portion, its normal and peptic ulcer, shallow or atrophic gastritis etc. Occur together, also can individually occur.The indigestion symptoms such as the most common the most glutted, pantothenic acid, belch, irregularities stomachache.Chronic Erosive gastritis is very important to the harm of health, if can not treat in time, effectively contains advancing of disease, So will produce peptic ulcer, upper gastrointestinal hemorrhage even occur, directly jeopardizes the life of patient.

The medicine of Current therapeutic erosive gastritis mostly is chemical drugs, and it is expensive, and side effect is big, and cures and taken Between long.Therefore, urgent need one is economical and practical, toxic and side effects is low, and the medicine of the energy above-mentioned disease of rapid healing, and Chinese medicine is being controlled Treat chronic disease aspect one to all playing an important role.But, current patients with gastric disease is large number of, and market medicine is not for should Ask, therefore, develop a kind of new pharmaceutical composition that can effectively treat erosive gastritis and seem particularly necessary.The traditional Chinese medical science thinks rotten The generation of rotten property gastritis is many to be caused by liver-fire, Deficiency and coldness of spleen and stomach, qi depression to blood stasis, during treatment many with purging liver-fire, invigorating the spleen and benefiting QI, invigorate blood circulation Blood stasis dispelling, to improve human metabolism as Main way.

Summary of the invention

For the present situation that existing erosive gastritis western medical treatment means are not enough, it is an object of the invention to provide a kind of safety, The medicine of the treatment erosive gastritis that toxic and side effects is little, this Chinese medicine has purging liver-fire, invigorating the spleen and benefiting QI, blood circulation promoting and blood stasis dispelling, dissipates Cold pain relieving, to improve the effect of human metabolism, when erosive gastritis, effect is notable.

It is an object of the invention to be achieved through the following technical solutions:

A kind of medicine treating erosive gastritis, is made up of the raw material of following parts by weight: Radix Codonopsis 12-18 part, Rhizoma Atractylodis Macrocephalae 7-12 part, Poria 11-17 part, Ramulus Cinnamomi 4-8 part, Radix Paeoniae Alba 10-15 part, Fructus Amomi 6-11 part, Radix Et Rhizoma Nardostachyos 8-12 part, Herba Artemisiae Anomalae 12-18 part, Os Sepiae 7-13 part, Rhizoma Zingiberis Recens 8-12 part, Rhizoma Corydalis 8-12 part, Radix Glycyrrhizae Preparata 4-10 part, 2-5 piece of Fructus Jujubae.

Further, a kind of medicine treating erosive gastritis, it is made up of the crude drug of following parts by weight: Radix Codonopsis 15 Part, the Rhizoma Atractylodis Macrocephalae 10 parts, 15 parts of Poria, Ramulus Cinnamomi 6 parts, the Radix Paeoniae Alba 12 parts, Fructus Amomi 8 parts, Radix Et Rhizoma Nardostachyos 10 parts, Herba Artemisiae Anomalae 15 parts, Os Sepiae 10 parts, 10 parts of Rhizoma Zingiberis Recens, Rhizoma Corydalis 10 parts, Radix Glycyrrhizae Preparata 6 parts, 3 pieces of Fructus Jujubae.

Further, described a kind of medicine treating erosive gastritis can make decoction, granule, pill according to a conventional method And capsule.Patient adheres to that taking two courses for the treatment of both can take effect, and per course for the treatment of is two weeks, and after taking 3 to 4 courses for the treatment of, symptom is big For alleviating.

The pharmacology of the present invention and having the beneficial effect that:

Radix Codonopsis sweet in the mouth, property is flat, stomach invigorating, and QI invigorating is eliminated the phlegm, promoted the production of body fluid；Rhizoma Atractylodis Macrocephalae sweet in the mouth, warm in nature, stomach invigorating, strong, diuresis, dampness, cure mainly Dyspepsia, diarrhea due to hypofunction of the spleen, rheumatalgia, the spleen strengthening and damp drying；Poria sweet in the mouth, light, property are put down, can eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind calming Calm the nerves, cure mainly dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, have loose bowels, palpitation and restlessness, insomnia forgetfulness, seminal emission Nebulousurine；Its nature and flavor acrid, sweet, warm of Ramulus Cinnamomi, enter lung, the heart, bladder warp, are to cure mainly the drugs for dispelling internal cold that interior cold is conventional, have complement sun, logical blood Arteries and veins, effect of warming the spleen and stomach；The Radix Paeoniae Alba is cool in nature, bitter in the mouth acid, is slightly cold, has blood-supplementing blood-nourishing, suppressing liver-YANG, easing the affected liver to relieve pain, astringing YIN to stop sweating Etc. effect；Fructus Amomi has removing dampness to whet the appetite, warming spleen and stopping diarrha, regulates the flow of vital energy antiabortive, and for turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is the most hungry, Deficiency and coldness of spleen and stomach, and vomiting is let out Rush down, pregnancy reactions, effect of frequent fetal movement；Radix Et Rhizoma Nardostachyos regulating QI to relieve pain, relieving stagnation and activating the spleen.For distension and fullness in the abdomen, inappetence, vomiting； External treatment is had a toothache, swelling of the feet；Herba Artemisiae Anomalae removing blood stasis with potent drugs stimulates the menstrual flow, hemostasia and detumescence, promoting digestion and removing stagnation；Os Sepiae astringing to arrest bleeding, treating spontaneous emission and leukorrhagia, antacid is only Bitterly, granulation promoting damp eliminating, this quality adstringency is dry, function convergence dampness, hemostasis, leukorrhagia stopping, with controlling lung gastrorrhagia, have blood in stool and women's Liver and kidney not Foot, the metrorrhagia of the debility of CHONG and REN meridians, the inferior card of red and white leukorrhea, all have good effect, because of its can relieving gastric hyperacidity to alleviate stomachache, existing clinic be used for treating gastritis, Peptic Ulcers hyperchlorhydria, effect relatively writes；Rhizoma Zingiberis Recens relieving the exterior syndrome by diaphoresis, warming middle-JIAO to arrest vomiting, warming the lung to relieve cough, solving toxin of fish and crab, solve poison of drug, it is adaptable to Affection of exogenous wind-cold, headache, phlegm retention, cough, gastrofrigid vomiting, after suffering the invasion and attack wet, cold of ice and snow, water, suddenly drink it with ginger decoction, can increase Enter blood, disperse cold-evil；Rhizoma Corydalis is invigorated blood circulation, circulation of qi promoting, pain relieving, be mainly used in stagnation of QI and blood all pains card, the pungent scattered temperature of this product is led to, can promoting the circulation of blood The middle stagnation of QI, stasis in gas, therefore specially control upper and lower all pains all over the body；Radix Glycyrrhizae Preparata spleen reinforcing stomach function regulating, Yiqi and vein recovery, for weakness of the spleen and stomach, asthenia Weak, severe palpitation, irregularly intermittent and regularly intermittent pulse；Fructus Jujubae tonifying the spleen and stomach, replenishing QI and blood, tranquilizing mind, adjust battalion to defend, and the property of medicine, main weakness of the spleen and stomach, QI and blood is not Foot, anorexia and loose stool, fatigue and weakness, palpitation and insomnia, woman hysteria, disharmony of nutrient QI with defensive QI, for diarrhea due to hypofunction of the spleen, cardiopalmus, have a sleepless night, night sweat, Thrombocytopenic purpura.Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Poria, Radix Glycyrrhizae Preparata compatibility, spleen invigorating is strong, controls deficiency of vital energy dyspepsia, Ramulus Cinnamomi, big Fructus Jujubae, the Radix Paeoniae Alba, the same use of Rhizoma Zingiberis Recens, play the merit promoting blood circulation to restore menstrual flow of warming spleen and stomach for dispelling cold, Rhizoma Corydalis, Os Sepiae and Fructus Amomi compatibility depressed liver-energy dispersing and QI regulating altogether, adjust altogether Regulating liver-QI spleen, Herba Artemisiae Anomalae and the same use of Radix Et Rhizoma Nardostachyos, blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, can be effectively improved human metabolism's ability.

Formula of Chinese materia medica preparation of the present invention by Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Poria, Ramulus Cinnamomi, the Radix Paeoniae Alba, Fructus Amomi, Radix Et Rhizoma Nardostachyos, Herba Artemisiae Anomalae, Os Sepiae, The Chinese medicine medicines collocation such as Rhizoma Zingiberis Recens, Rhizoma Corydalis, Radix Glycyrrhizae Preparata, Fructus Jujubae form, and pharmaceutical composition reasonable compatibility has played Synergistic work With, play altogether and strengthen the spleen and stomach and stomach and alleviating pain, the effect of blood circulation promoting and blood stasis dispelling, improve human metabolism's ability, erosive gastritis is had Significant curative effect, and treatment time is short, good effect, be difficult to recurrence after treatment, provides a kind of new for clinical treatment erosive gastritis Medication select.

Detailed description of the invention

The invention will be further described for example given below plan, but is not to be construed as scope Restriction, those skilled in the art, according to some nonessential improvement and adjustment to the present invention of present invention, still fall within this The protection domain of invention.

Embodiment 1:

A kind of medicine treating erosive gastritis, including: Radix Codonopsis 15 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 15 parts of Poria, Ramulus Cinnamomi 6 parts, the Radix Paeoniae Alba 12 Part, Fructus Amomi 8 parts, Radix Et Rhizoma Nardostachyos 10 parts, Herba Artemisiae Anomalae 15 parts, Os Sepiae 10 parts, 10 parts of Rhizoma Zingiberis Recens, Rhizoma Corydalis 10 parts, Radix Glycyrrhizae Preparata 6 parts, Fructus Jujubae 3 Piece.Weighing the medical material of above-mentioned weight portion, boiling 3 times, add 10 times amount soak by water 10 minutes for the first time, second time adds 8 times amount soak by water 20 minutes, third time adds 8 times amount soak by water 20 minutes, filters, and after merging decocting liquid, obtains medicine of the present invention Decoction.

Embodiment 2:

A kind of medicine treating erosive gastritis, including: Radix Codonopsis 12 parts, the Rhizoma Atractylodis Macrocephalae 7 parts, 11 parts of Poria, Ramulus Cinnamomi 4 parts, the Radix Paeoniae Alba 10 parts, Fructus Amomi 6 parts, Radix Et Rhizoma Nardostachyos 8 parts, Herba Artemisiae Anomalae 12 parts, Os Sepiae 7 parts, 8 parts of Rhizoma Zingiberis Recens, Rhizoma Corydalis 8 parts, Radix Glycyrrhizae Preparata 4 parts, 2 pieces of Fructus Jujubae.Weigh Stating the medical material of weight portion, boiling 3 times, add 10 times amount soak by water 10 minutes for the first time, second time adds 8 times amount decoctings Boiling 20 minutes, third time adds 8 times amount soak by water 20 minutes, filters, and after merging decocting liquid, obtains the decoction of medicine of the present invention.

Embodiment 3:

A kind of medicine treating erosive gastritis, including: Radix Codonopsis 18 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, 17 parts of Poria, Ramulus Cinnamomi 8 parts, the Radix Paeoniae Alba 15 Part, Fructus Amomi 11 parts, Radix Et Rhizoma Nardostachyos 12 parts, Herba Artemisiae Anomalae 18 parts, Os Sepiae 13 parts, 12 parts of Rhizoma Zingiberis Recens, Rhizoma Corydalis 12 parts, Radix Glycyrrhizae Preparata 10 parts, Fructus Jujubae 5 Piece.Weighing the medical material of above-mentioned weight portion, boiling 3 times, add 10 times amount soak by water 10 minutes for the first time, second time adds 8 times amount soak by water 20 minutes, third time adds 8 times amount soak by water 20 minutes, filters, and after merging decocting liquid, obtains medicine of the present invention Decoction.

Clinical data: the patient suffering from erosive gastritis to 200 examples carries out clinical trial, in this 200 example patient, the age is Big 55 years old, minimum 28 years old, it is randomly divided into 4 groups, first group of 50 example, second group of 50 example, the 3rd group of 50 examples, the 4th group of 50 examples, the 4th Group patient takes each 2 of Western medicine preparation sucralfate chewable tablet (respecting space pharmacy in vain), 1 day 3 times.Four groups of cases are at aspects such as ages Through statistical analysis no significant difference, there is comparability.

Diagnostic criteria: with reference to the standard of " new Chinese medicine guideline of clinical investigations ", differential diagnosis in tcm is said the most glutted, general The indigestion symptoms such as acid, belch, irregularities stomachache, Repeated Hemorrhage.From gastroscope, observation and expression is that Stomach in Patients mucosa occurs Multiple excipuliforms, expanding folded shape or pimple sample protuberance, diameter 5～10mm, mucomembranous defect seen from top or umbilicus sample depression, center has Erosion, protuberance is the most without blush, but is often accompanied by the erythema that size is similar.

Therapeutic Method: patient starts to take after being diagnosed as erosive gastritis, takes enforcement respectively by the first to three group patient Example 1, embodiment 2, embodiment 3, decoction prepared by embodiment, sooner or later respectively take 1 time, the 4th group of patient takes Western medicine preparation thiosugar Each 2 of aluminum chewable tablet (respecting space pharmacy in vain), 1 day 3 times.

Efficacy evaluation: recovery from illness: clinical symptoms, sign disappear, gastric mucosa excipuliform under gastroscope, expand folded shape or pimple sample grand Rise and disappear, without rotten to the corn position and erythema；Effective: clinical symptoms, sign disappear, gastric mucosa excipuliform under gastroscope, expand folded shape or Pimple sample protuberance significantly reduces, and rotten to the corn position and erythema reduce；Effective: clinical symptoms, sign alleviate, gastric mucosa wart under gastroscope Shape, expanding folded shape or pimple sample protuberance slightly reduces, rotten to the corn position and erythema have reduced；Invalid: not reach effective standard Or anti-deterioration person.

Four groups of patient's curative effect statistical results are shown in such as table 1 below.

Clinical efficacy statistical result shows, the cure rate of first group to the 3rd group patient is up to more than 90%, and has no adverse reaction, And the 4th group of patient's cure rate is relatively low, and the malaise symptoms such as anaphylaxis occur.Chinese medicine of the present invention is to suffering from erosive gastritis Patient have significant curative effect, and without any clinical adverse, show Chinese medicine clinical practice safety of the present invention, nontoxic pair Effect.

Claims

1. the medicine treating erosive gastritis, it is characterised in that described medicine is made up of the raw material of following parts by weight: party Ginseng 12-18 part, Rhizoma Atractylodis Macrocephalae 7-12 part, Poria 11-17 part, Ramulus Cinnamomi 4-8 part, Radix Paeoniae Alba 10-15 part, Fructus Amomi 6-11 part, Radix Et Rhizoma Nardostachyos 8-12 part, Herba Artemisiae Anomalae 12-18 part, Os Sepiae 7-13 part, Rhizoma Zingiberis Recens 8-12 part, Rhizoma Corydalis 8-12 part, Radix Glycyrrhizae Preparata 4-10 part, 2-5 piece of Fructus Jujubae.

A kind of medicine treating erosive gastritis the most according to claim 1, it is characterised in that described medicine is by following The crude drug composition of parts by weight: Radix Codonopsis 15 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 15 parts of Poria, Ramulus Cinnamomi 6 parts, the Radix Paeoniae Alba 12 parts, Fructus Amomi 8 parts, Radix Et Rhizoma Nardostachyos 10 parts, Herba Artemisiae Anomalae 15 parts, Os Sepiae 10 parts, 10 parts of Rhizoma Zingiberis Recens, Rhizoma Corydalis 10 parts, Radix Glycyrrhizae Preparata 6 parts, 3 pieces of Fructus Jujubae.