CN108143917A - It is a kind of to be used to treat pill medicine of coronary heart disease and preparation method thereof - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to a kind of pill medicine for being used to treat coronary heart disease be provided according to the understanding mechanism of Chinese traditional treatment coronary heart disease, each component and its mass parts ratio of the drug are as follows：Yellow 100~350g of Stilbene, 100~160g of sealwort, 80~180g of Radix Codonopsis, 80~180g of Radix Salviae Miltiorrhizae, 100~180g of pueraria lobata, 50~160g of Rhizoma Atractylodis Macrocephalae, 30~100g of Herba Epimedii, 30~120g of hawthorn, 100~200g of glutinous rehmannia, 100~160g of Poria cocos, 80~180g of Radix Angelicae Sinensis, 25~60g of the coptis, 80~160g of corydalis tuber, 15~70g of cassia twig, 100~160g of ganoderma lucidum, 30~160g of ginseng, 10~45g of asarum, 30~150g of Radix Glycyrrhizae, 50~150g of safflower, 60~150g of the radix paeoniae rubrathe；Drug provided by the invention is a good Chinese prescription.

Description

It is a kind of to be used to treat pill medicine of coronary heart disease and preparation method thereof

Technical field

The invention belongs to field of traditional Chinese, and in particular to and it is a kind of for treating the pill medicine of coronary heart disease, particularly supply The field of the pill medicine that patients with coronary heart disease uses and preparation method thereof.

Background technology

Motherland's medicine thinks：Coronary heart disease is the abbreviation of coronary cardiopathy, is a kind of most common heart disease, refers to Because of caused by coronary artery stenosis, blood supply insufficiency myocardial dysfunction and（Or）Organic disease, therefore also known as ischemic myocardial Disease.Coronary heart disease is a kind of organic by coronary artery（Atherosclerosis or dynamic property vasopasm）Caused by stenosis or occlusion Myocardial ischemia-anoxemia（Angina pectoris）Or myocardial necrosis（Myocardial infarction）Heart disease, also known as ischemic heart disease.The hair of coronary heart disease Raw degree and number with coronary atherosclerosis has substantial connection, while suffers from the diseases such as hypertension, diabetes, with And obesity, bad life habits etc. are to induce the principal element of the disease.Coronary heart disease be the highest disease of the global death rate it One, according to World Health Organization's report of 2011, Chinese coronary heart disease death number has arranged second place of the world.

So, just how to find a kind of Chinese medicine composition that can effectively treat coronary heart disease, be those skilled in the art urgently It solves the problems, such as.

Invention content

With the continuous development of China's traditional Chinese medicine, in treatment coronary heart disease, people gradually appreciate Chinese traditional treatment It the advantages of coronary heart disease, and good effect, the advantages such as quick, toxic side effect is small over the course for the treatment of, is preced with for existing western medical treatment The present situation of worry, the purpose of the invention is to provide a kind of for treating the pill medicine of coronary heart disease, to solve coronary disease sufferer The problem of person gets well early.The drug be using common Chinese medicine as raw material, by selecting rational drug and mass parts ratio, Above-mentioned coronary heart disease can effectively be treated.

To achieve the purpose that foregoing invention, the technical solution adopted in the present invention is：One kind is provided for treating coronary heart disease Pill medicine and preparation method thereof, which is characterized in that each component and mass parts of the drug are than as follows：

Yellow 100~350g of Stilbene, 100~160g of sealwort, 80~180g of Radix Codonopsis, 80~180g of Radix Salviae Miltiorrhizae, 100~180g of pueraria lobata, Rhizoma Atractylodis Macrocephalae 50~160g, 30~100g of Herba Epimedii, 30~120g of hawthorn, 100~200g of glutinous rehmannia, 100~160g of Poria cocos, Radix Angelicae Sinensis 80~ 180g, 25~60g of the coptis, 80~160g of corydalis tuber, 15~70g of cassia twig, 100~160g of ganoderma lucidum, 30~160g of ginseng, asarum 10 ~45g, 30~150g of Radix Glycyrrhizae, 50~150g of safflower, 60~150g of the radix paeoniae rubrathe, auxiliary material：Appropriate starch.

It is a kind of to be used to treat pill medicine of coronary heart disease and preparation method thereof, which is characterized in that each group of the drug Divide and mass parts are than as follows：

Yellow 115~310g of Stilbene, 115~140g of sealwort, 90~160g of Radix Codonopsis, 90~160g of Radix Salviae Miltiorrhizae, 115~160g of pueraria lobata, Rhizoma Atractylodis Macrocephalae 56~140g, 36~90g of Herba Epimedii, 36~105g of hawthorn, 115~170g of glutinous rehmannia, 115~140g of Poria cocos, 90~160g of Radix Angelicae Sinensis, 30~52g of the coptis, 90~140g of corydalis tuber, 20~60g of cassia twig, 115~140g of ganoderma lucidum, 36~140g of ginseng, asarum 12~ 40g, 36~130g of Radix Glycyrrhizae, 56~130g of safflower, 70~130g of the radix paeoniae rubrathe, auxiliary material：Appropriate starch.

It is a kind of to be used to treat pill medicine of coronary heart disease and preparation method thereof, which is characterized in that each group of the drug Divide and mass parts are than as follows：

Yellow Stilbene 280g, sealwort 120g, Radix Codonopsis 140g, Radix Salviae Miltiorrhizae 140g, pueraria lobata 140g, Rhizoma Atractylodis Macrocephalae 120g, Herba Epimedii 80g, hawthorn 95g, Glutinous rehmannia 150g, Poria cocos 120g, Radix Angelicae Sinensis 140g, coptis 45g, corydalis tuber 120g, cassia twig 52g, ganoderma lucidum 120g, ginseng 120g, asarum 35g, Radix Glycyrrhizae 118g, safflower 118g, radix paeoniae rubrathe 118g, auxiliary material：Appropriate starch.

It is a kind of to be used to treat pill medicine of coronary heart disease and preparation method thereof, which is characterized in that the method includes as follows Step is prepared：

A, after above-mentioned raw materials Chinese medicine being picked impurity, dust and drying, it is for use to be ground into superfine end according to mass parts ratio；

B, the method for preparing Chinese kmedicine bolus agent according to tradition after above-mentioned ground superfine myrrh object and starch sieving, is put into Mixing is mixed in medicine device, is then prepared into water-bindered pill agent（The granularity of its water-bindered pill is：3.8mm~4.0mm）, and then dry, packing is close It seals to obtain the final product.

It is a kind of for treating pill medicine of coronary heart disease and preparation method thereof, which is characterized in that the instructions of taking is：It will The water pill medicine prepared to take 2 times a day, and once a dose sooner or later, dosage 6g/ times, warm water delivery service.It should keep away simultaneously Exempt from high fat diet, adhere to suitable physical exertion, release is constrained or intense strain, and to control blood pressure, blood glucose and blood fat etc. Risk factor.15 days as a treatment course, 1~2 course for the treatment of of taking medicine, symptom is controlled, but needs to take for a long time.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine It carries.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component：

Yellow Stilbene, nature and flavor：Sweet, tepor has the effect of invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, expelling pus and promoting granulation, for treating the deficiency of vital energy Weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult to burst, burst for a long time and does not holds back, The diseases such as flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes, chronic rephrilis protinuria, diabetes；

Sealwort, nature and flavor：It is sweet in flavor, mild-natured, there is the effect of boosting qi and nourishing yin, invigorating the spleen, moistening lung, kidney-nourishing, for treating deficiency of spleen-QI and stomach-QI, body Tired weak, deficiency of stomach-Yin, dry deficiency of food, deficiency syndrome of the lung cough caused by dryness, overstrain cough hemoptysis, asthenia of essence and blood, soreness and weakness of waist and knees, poliosis, interior heat disappear Yearningly；

Radix Codonopsis, nature and flavor：It is sweet, flat, there is the effect of tonifying middle-Jiao and Qi, strengthening spleen and tonifying lung, for treating spleen and lung weakness, shortness of breath and palpitation, food Few loose stool, virtual asthma cough, Heat Diabetes；

Radix Salviae Miltiorrhizae, nature and flavor：Bitter, cold nature have the effect of promoting blood circulation, menstruction regulating and pain relieving, nourishing blood and tranquilization, cool blood to disappear carbuncle, are used for Treat menoxenia, dysmenorrhoea, Amenorrhea, postpartum stasis of blood, trusted subordinate's pain, a lump in the abdomen causing distension and pain, the swelling and pain of hot numbness, traumatic injury, Heat enters ying blood, dysphoria, vexed insomnia, ulcerative carbuncle pyogenic infections；

Pueraria lobata, nature and flavor：It is sweet in flavor, pungent, cool in nature, it brings down a fever with expelling pathogenic factors from muscles and skin, the effect of promoting eruption promotes the production of body fluid to quench thirst, Shengyang Zhixie, for treating Exterior syndrome fever, stiff nape and back, measles without adequate eruption, pyreticosis is thirsty, the deficiency of Yin is quenched one's thirst, heat is purged heat dysentery, splenasthenic diarrhea；

Rhizoma Atractylodis Macrocephalae, nature and flavor：It is bitter, sweet, warm, there is the effect of air making-up and spleen enlivening, eliminate dampness and have diuretic effect, hidroschesis, tocolysis, for treating Spleen-Qi Deficiency The diseases such as weak, anorexia and loose stool, phlegm and retained fluid oedema, exterior deficiency spontaneous perspiration, fetal irritability；

Herba Epimedii, nature and flavor：It is acrid flavour, sweet, warm-natured, there is the effect of tonifying kidney and strengthening yang, dispelling wind and eliminating dampness, strengthening tendons key bone, for treating sun Impotence seminal emission, empty cold infertility, frequent micturition mistake Chu, dyspnea and cough due to deficiency of the kidney, soreness and weakness of waist and knees, arthralgia pain due to rheumatism, hemiplegia, four limbs are meciless；

Hawthorn, nature and flavor：Sour sweet, tepor, it is nontoxic, there is digestion gathered food, change the effect of stagnant stasis of blood, stagnate for Therapeutic diet, gastral cavity abdomen is swollen Bitterly, dysentery, dysmenorrhea due to blood stasis, amenorrhoea, postpartum abdominal pain, lochiorrhagia；

Glutinous rehmannia, nature and flavor：Radix rehmanniae recen：It is cold in nature, sweet in flavor, fresh rehmannia root：It is cold in nature, sweet in flavor, bitter, radix rehmanniae recen：With clearing heat and cooling blood, yin-nourishing, The effect of promoting the production of body fluid, fresh rehmannia root：The effect of with clearing heat and promoting fluid, cool blood, hemostasis, belongs to the heat-clearing drug of antipyretic subordinate classification, Radix rehmanniae recen：For treating the deep red polydipsia of pyreticosis tongue, yin asthenia generating intrinsic heat, hectic fever due to yin labor heat, Heat Diabetes, hematemesis and epistaxis, spot dermexanthesis；Freshly It is yellow：For treating the deep red polydipsia of consumption of YIN caused by febrile disease, tongue, febrile virulent maculae, haematemesis, bleeding from five sense organs or subcutaneous tissue, abscess of throat；

Poria cocos, nature and flavor：It is sweet in flavor, light, mild-natured, there is the effect of clearing damp and promoting diuresis, invigorating the spleen, calming heart, for treating oedema oliguria, phlegm and retained fluid Feel dizzy and heart palpitations, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear；

Radix Angelicae Sinensis, nature and flavor：Warm-natured, acrid-sweet flavor, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation the effect of, for treat the deficiency of blood, Sallow complexion, dizziness palpitaition, the deficiency of blood have the stagnant irregular menstruation of the stasis of blood, Amenorrhea, dysmenorrhoea, deficient cold type abdominal pain, coronary heart disease heart strand concurrently Bitterly, arthralgia pain due to rheumatism, traumatic injury；

The coptis, nature and flavor：Cold in nature, bitter, has a purging intense heat, eliminating dampness, removing toxic substances, the effect of desinsection, row heat toxin during for treating, typhoid fever, Inverse, bacillary dysentery that excess heat is vexed, feeling of fullness is vomitted, heat rush down abdominal pain, lung knot by, spit, be defeated in battle, lower blood, quench one's thirst, infantile malnutrition due to digestive disturbances or intestinalparasites, roundworm disease, pertussis, pharynx Larynx swelling and pain, pinkeye, aphtha, skin sore, eczema, the burning hot wound of soup；

Corydalis tuber, nature and flavor：Acrid, bitter, warm, it is nontoxic, there is promoting blood circulation, dissipate the effect of stasis of blood, qi-regulating, analgesic, for treating trusted subordinate's waist and knee All pains, irregular menstruation, abdominal mass, metrorrhagia, postpartum anemic fainting, lochiorrhagia, traumatic injury；

Cassia twig, nature and flavor：It is pungent, sweet, warm-natured, there is the effect of expelling cold and relieving exterior syndrome, warming meridian, activating YANG and prormoting functioning of QI, for treating chill table The diseases such as card, numbness and ache of cold dampness, peripheral coldness, closed dysmenorrhea, Disorder lumps in the abdomen caking, the obstruction of qi in the chest, palpitaition, phlegm and retained fluid, difficult urination；

Ganoderma lucidum, nature and flavor：It is sweet, flat, it is nontoxic, there is the effect of replenishing qi and blood, tranquilizing mind, strengthening the spleen and stomach, for treating consumptive disease, palpitaition, mistake The diseases such as dormancy, dizziness, spiritlessness and weakness, chronic cough asthma, coronary heart disease, silicosis, tumour；

Ginseng, nature and flavor：Sweet slight bitter, temperature, have reinforce vital energy, prevent prolapse and engender liquid, calm the nerves the effect of, for treat internal lesion caused by overexertion it is deficient, food Less, burnout, regurgitation and emesis, stool lingering diarrhea, cough of deficient and syndrome characterized by dyspnea, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, impotence, frequent micturition, disappear Yearningly, the diseases such as woman uterine bleeding, infantile chronic fright and perennial and irrecoverable weakness, all qi-blood-body fluid deficiencies；

Asarum, nature and flavor：It is pungent, warm, there is the effect of expelling wind and clearing away cold, sensible analgesic, warming lung and resolving fluid, for treating anemofrigid cold, head Bitterly, it has a toothache, have a stuffy nose nasosinusitis, arthralgia pain due to rheumatism, sputum cough；

Radix Glycyrrhizae, nature and flavor：It is sweet, flat, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, use It swells in treatment burnout deficiency of food, the thin face Huang of flesh, palpitation, abdominal pain loose stool, four limbs contraction, hysteria, cough and asthma, throat Bitterly, the diseases such as ulcerative carbuncle swelling and pain, infant fetal toxin and drug, food poisoning；

Safflower, nature and flavor：It is acrid flavour, warm-natured, there is the effect of promoting blood circulation can be through, stasis-dispelling and pain-killing, for treating Amenorrhea, dysmenorrhoea, the postpartum stasis of blood The diseases such as resistance abdominal pain, born of the same parents' numbness is pained, and a lump in the abdomen causing distension and pain, traumatic injury, arthralgia, middle windage yaw are completed, macula；

The radix paeoniae rubrathe, nature and flavor：It is bitter, be slightly cold, there is the effect of clearing heat and cooling blood, promoting blood circulation, for treat febrile virulent maculae, hematemesis and epistaxis, Discharging fresh blood stool, carbuncle swells sore, amenorrhoea, dysmenorrhoea, collapses the diseases such as band stranguria with turbid discharge, the stagnant hypochondriac pain of the stasis of blood, the accumulation of hernia lump in the abdomen, injury from falling down at red eye, swell pain.

Drug of the present invention is the principle based on Chinese traditional treatment coronary heart disease, from the pathomechanism according to coronary heart disease and pharmacological action Think：With regard to coronary heart disease, each raw material herbal medicine efficacy in drug provided by the present invention is played altogether, has good treatment to above-mentioned disease Effect.

Specific embodiment

A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned coronary heart disease, the medicine prepared using the formula Object good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific reality of the present invention The mode of applying is described in further detail：

Embodiment 1：

A kind of pill medicine for being used to treat coronary heart disease, which is characterized in that each component and mass parts ratio of the drug are as follows It is shown：

Yellow Stilbene 280g, sealwort 120g, Radix Codonopsis 140g, Radix Salviae Miltiorrhizae 140g, pueraria lobata 140g, Rhizoma Atractylodis Macrocephalae 120g, Herba Epimedii 80g, hawthorn 95g, Glutinous rehmannia 150g, Poria cocos 120g, Radix Angelicae Sinensis 140g, coptis 45g, corydalis tuber 120g, cassia twig 52g, ganoderma lucidum 120g, ginseng 120g, asarum 35g, Radix Glycyrrhizae 118g, safflower 118g, radix paeoniae rubrathe 118g, auxiliary material：Appropriate starch.

Embodiment 2：

A kind of pill medicine for being used to treat coronary heart disease, which is characterized in that each component and mass parts ratio of the drug are as follows It is shown：

Yellow Stilbene 310g, sealwort 140g, Radix Codonopsis 160g, Radix Salviae Miltiorrhizae 160g, pueraria lobata 160g, Rhizoma Atractylodis Macrocephalae 140g, Herba Epimedii 90g, hawthorn 105g, Glutinous rehmannia 170g, Poria cocos 140g, Radix Angelicae Sinensis 160g, coptis 52g, corydalis tuber 140g, cassia twig 60g, ganoderma lucidum 140g, ginseng 140g, asarum 40g, Radix Glycyrrhizae 130g, safflower 130g, radix paeoniae rubrathe 130g, auxiliary material：Appropriate starch.

Embodiment 3：

A kind of pill medicine for being used to treat coronary heart disease, which is characterized in that each component and mass parts ratio of the drug are as follows It is shown：

Yellow Stilbene 350g, sealwort 160g, Radix Codonopsis 180g, Radix Salviae Miltiorrhizae 180g, pueraria lobata 180g, Rhizoma Atractylodis Macrocephalae 160g, Herba Epimedii 100g, hawthorn 120g, glutinous rehmannia 200g, Poria cocos 160g, Radix Angelicae Sinensis 180g, coptis 60g, corydalis tuber 160g, cassia twig 70g, ganoderma lucidum 160g, ginseng 160g, Asarum 45g, Radix Glycyrrhizae 150g, safflower 150g, radix paeoniae rubrathe 150g, auxiliary material：Appropriate starch.

Model case：

Through clinical conditions patients with coronary heart disease totally 1074, the age is 670 of 62 years old or more, only 404 for 62 years old with Under.What symptom was controlled in 1074 patients has 850, effective 117, invalid 107.Total effective rate is up to 90%.

Claims (3)

1. a kind of pill medicine for being used to treat coronary heart disease, which is characterized in that each component and mass parts of the drug are such as Shown in lower：

Yellow 100~350g of Stilbene, 100~160g of sealwort, 80~180g of Radix Codonopsis, 80~180g of Radix Salviae Miltiorrhizae, 100~180g of pueraria lobata, Rhizoma Atractylodis Macrocephalae 50~160g, 30~100g of Herba Epimedii, 30~120g of hawthorn, 100~200g of glutinous rehmannia, 100~160g of Poria cocos, Radix Angelicae Sinensis 80~ 180g, 25~60g of the coptis, 80~160g of corydalis tuber, 15~70g of cassia twig, 100~160g of ganoderma lucidum, 30~160g of ginseng, asarum 10 ~45g, 30~150g of Radix Glycyrrhizae, 50~150g of safflower, 60~150g of the radix paeoniae rubrathe, auxiliary material：Appropriate starch.

2. the pill medicine according to claim 1 for being used to treat coronary heart disease, which is characterized in that each group of the drug Divide and mass parts are than as follows：

Yellow 115~310g of Stilbene, 115~140g of sealwort, 90~160g of Radix Codonopsis, 90~160g of Radix Salviae Miltiorrhizae, 115~160g of pueraria lobata, Rhizoma Atractylodis Macrocephalae 56~140g, 36~90g of Herba Epimedii, 36~105g of hawthorn, 115~170g of glutinous rehmannia, 115~140g of Poria cocos, 90~160g of Radix Angelicae Sinensis, 30~52g of the coptis, 90~140g of corydalis tuber, 20~60g of cassia twig, 115~140g of ganoderma lucidum, 36~140g of ginseng, asarum 12~ 40g, 36~130g of Radix Glycyrrhizae, 56~130g of safflower, 70~130g of the radix paeoniae rubrathe, auxiliary material：Appropriate starch.

3. according to claim 1 to 2 for treating the pill medicine of coronary heart disease, which is characterized in that the drug it is each A component and mass parts are than as follows：

Yellow Stilbene 280g, sealwort 120g, Radix Codonopsis 140g, Radix Salviae Miltiorrhizae 140g, pueraria lobata 140g, Rhizoma Atractylodis Macrocephalae 120g, Herba Epimedii 80g, hawthorn 95g, Glutinous rehmannia 150g, Poria cocos 120g, Radix Angelicae Sinensis 140g, coptis 45g, corydalis tuber 120g, cassia twig 52g, ganoderma lucidum 120g, ginseng 120g, asarum 35g, Radix Glycyrrhizae 118g, safflower 118g, radix paeoniae rubrathe 118g, auxiliary material：Appropriate starch.