CN106237309A - 一种治疗气滞血瘀、肌瘤囊肿病证的丸剂药物及制备方法 - Google Patents
一种治疗气滞血瘀、肌瘤囊肿病证的丸剂药物及制备方法 Download PDFInfo
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Abstract
本发明属于中药制剂领域,目的是根据中医对气滞血瘀、肌瘤囊肿病证的认识机理而提供的一种治疗气滞血瘀、肌瘤囊肿病证的丸剂药物,所述药物的各个组分及其质量份比如下:陈皮、枳实(炒)、茵陈、木香、香附(炒)、枳壳、郁金、神曲、沉香、茯苓、乌药、川楝子、佛手、麦芽、山楂、白术、川芎、丹参、桃仁、红花、三棱(醋制)、莪术、穿山甲、鳖甲、龟板、莱菔子、青皮、青木香、薤白、香橼、焦槟榔、干姜、姜黄、五灵脂、益母草、鸡血藤、苏木、当归、血竭、赤芍;本发明提供的药物是一个标本兼治的中药组方。
Description
技术领域
本发明属于中药制剂领域,具体涉及一种治疗气滞血瘀、肌瘤囊肿病证的丸剂药物,特别是供气滞血瘀、肌瘤囊肿病证的丸剂药物及制备方法的领域。
背景技术
气滞血瘀、肌瘤囊肿病证由来已久,其形成大多与人体情绪不稳、心情抑郁、精神紧张、心志不遂、生活环境发生改变等因素相关密切。其形成有一个较长的过程,并随着情绪、饮食、年龄、体质、环境、疾病等诸多因素的变化而改变。气滞血瘀、癥瘕积聚病证的发病倾向,大多具有明显的“不通畅”特征。例如:顽固性头痛、抑郁症、脑梗塞、心肌梗塞、胆囊炎、肠功能紊乱、乳腺小叶增生、痛经、子宫肌瘤、恶性肿瘤等。随着社会的发展,生活压力的不断加大、饮食和环境等因素的影响,上述疾病的临床发病率近年有显著上升趋势。
那么,就如何找到一种可有效治疗气滞血瘀、肌瘤囊肿病证的药物,是我们目前急需要解决的问题。
发明内容
随着我国中医中药学的不断发展,在治疗气滞血瘀、肌瘤囊肿病证上,人们逐渐意识到了中医治疗气滞血瘀、肌瘤囊肿病证的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗气滞血瘀、肌瘤囊肿病证的现状,本发明的目的是在于提供一种治疗气滞血瘀、肌瘤囊肿病证的丸剂药物,以解决气滞血瘀、肌瘤囊肿病证患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及其质量份比,可有效治疗上述气滞血瘀、肌瘤囊肿病证。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种治疗气滞血瘀、肌瘤囊肿病证的丸剂药物及制备方法,其特征在于,所述药物的各个组分及其其质量份比如下所示:
陈皮30~100g、 枳实(炒)50~120g、茵陈60~160g、木香30~120g、香附(炒)80~160g、枳壳30~100g、郁金80~160g、神曲100~160g、沉香30~50g、茯苓100~160g、乌药80~160g、川楝子80~160g、佛手30~100g、麦芽100~160g、山楂30~100g、白术100~160g、川芎50~100g、丹参80~160g、桃仁80~160g、红花50~120g、三棱(醋制)80~160g、莪术80~160g、穿山甲30~100g、鳖甲100~320g、龟板90~320g、莱菔子50~100g、青皮50~150g、青木香30~100g、薤白50~100g、香橼30~60g、焦槟榔30~90g、干姜30~100g、姜黄50~160g、五灵脂50~160g、益母草150~320g、鸡血藤150~260g、苏木50~160g、当归80~160g、血竭10~15g、赤芍40~120g。
一种治疗气滞血瘀、肌瘤囊肿病证的丸剂药物及制备方法,其特征在于,所述药物的各个组分及其其质量份比如下所示:
陈皮40~90g、 枳实(炒)60~100g、茵陈70~140g、木香40~100g、香附(炒)90~140g、枳壳40~90g、郁金90~140g、神曲115~140g、沉香40~42g、茯苓115~140g、乌药90~140g、川楝子90~140g、佛手40~90g、麦芽115~140g、山楂40~90g、白术115~140g、川芎60~90g、丹参90~140g、桃仁90~140g、红花60~100g、三棱(醋制)90~140g、莪术90~140g、穿山甲40~90g、鳖甲115~280g、龟板100~280g、莱菔子60~90g、青皮60~130g、青木香40~90g、薤白60~90g、香橼40~50g、焦槟榔40~80g、干姜40~90g、姜黄60~140g、五灵脂60~140g、益母草170~280g、鸡血藤170~230g、苏木60~140g、当归90~140g、血竭11~13g、赤芍50~100g。
一种治疗气滞血瘀、肌瘤囊肿病证的丸剂药物及制备方法,其特征在于,所述“最佳方案”的药物的各个组分及其其质量份比如下所示:
陈皮80g、枳实(炒)90g、茵陈120g、木香90g、香附(炒)120g、枳壳80g、郁金120g、神曲120g、沉香36g、茯苓120g、乌药120g、川楝子120g、佛手80g、麦芽120g、山楂80g、白术120g、川芎90g、丹参120g、桃仁120g、红花90g、三棱(醋制)120g、莪术120g、穿山甲80g、鳖甲250g、龟板260g、莱菔子80g、青皮115g、青木香80g、薤白80g、香橼45g、焦槟榔70g、干姜80g、姜黄120g、五灵脂120g、益母草250g、鸡血藤200g、苏木120g、当归120g、血竭12g、赤芍90g。
一种治疗气滞血瘀、肌瘤囊肿病证的丸剂药物及制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、将上述原料中药拣去杂质、粉尘及干燥后,按照质量份比共研为极细末待用;
B、按照传统制备中药水丸剂的方法,将研磨好的极细末药物过筛后,放入药器中混合拌均,然后制备成水丸剂(其水丸的粒度为:4.7mm~4.8mm),进而晒干,分装密封即可。
一种治疗气滞血瘀、肌瘤囊肿病证的丸剂药物及制备方法,其特征在于,所述服用方法为:将制备好的水丸剂药物以每日三次服用,早中晚各服一次,给药量5g/次,温开水送服,30天为1个疗程,服药5~7个疗程,体征恢复正常,气机畅达,气滞调顺,包块消失,血瘀消除,癥瘕排解,积聚平复。经检查:体内组织器官形态及功能完全正常。
本发明组方中的各原料中药在中国药典、中国辞典以及其中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
陈皮,性味:苦、辛、温,具有理气健脾、调中、燥湿、化痰之功效,用于治疗脾胃气滞之脘腹胀满或疼痛、消化不良、湿浊阻中之胸闷腹胀、纳呆便溏、痰湿壅肺之咳嗽气喘、食少吐泻、咳嗽痰多等症;
枳实(炒)性味:苦、寒,具有破气、散痞、泻痰、消积之功效,用于治疗胸腹胀满、胸痹、痞痛、痰癖、水肿、食积、便秘、胃下垂、子宫下垂、脱肛;
茵陈,性味:苦、辛、微寒,具有清湿热、退黄疸之功效,用于治疗黄疸尿少、湿疮瘙痒、传染性黄疸型肝炎;
木香,性味:辛苦、温,具有行气止痛、温中和胃之功效,用于治疗中寒气滞、胸腹胀痛、呕吐、泄泻、下痢里急后重、寒疝等症;
香附(炒),性味:辛微苦甘、平,具有理气解郁、止痛调经之功效,用于治疗肝胃不和、气郁不舒、胸腹胁胀痛、痰饮痞满、***、崩漏带下;
枳壳,性味:苦、酸、性微寒,具有理气宽胸、行滞消积之功效,用于治疗胸隔痞满、胁肋胀痛、食积不化、脘腹胀满、下痢后重、脱肛、子宫脱垂;
郁金,性味:辛苦、凉,具有行气解郁、凉血破瘀之功效,用于治疗胸腹胁肋诸痛、失心癫狂、热病神昏、吐血、衄血、尿血、血淋、妇女倒经、黄疸等症;
神曲,性味:甘、辛、温,无毒,具有健脾和胃、消食化积之功效,用于治疗饮食停滞、消化不良、脘腹胀满、食欲不振、呕吐泻痢;
沉香,性味:味辛、苦、性微温,具有行气止痛、温中止呕、纳气平喘之功效,用于治疗胸腹胀闷疼痛、胃寒呕吐呃逆、肾虚气逆喘急;
茯苓,性味:甘、淡、平,具有渗湿利水、健脾和胃、宁心安神之功效,用于治疗小便不利、水肿胀满、痰饮咳逆、呕吐、脾虚食少、泄泻、心悸不安、失眠健忘、遗精白浊;
乌药,性味:辛、温,具有行气止痛、温肾散寒之功效,用于治疗胸胁满闷、脘腹胀痛、头痛、寒疝疼痛、痛经及产后腹痛、尿频、遗尿等症;
川楝子,性味:苦、寒,有毒,具有除湿热、清肝火、止痛、杀虫之功效,用于治疗热厥心痛、胁痛、疝痛、虫积腹痛等症;
佛手,性味:辛、苦、酸、温,具有舒肝理气、和胃止痛之功效,用于治疗肝胃气滞、胸胁胀痛、胃脘痞满、食少呕吐;
麦芽,性味:甘、平,具有消食化积、回乳之功效,用于治疗食积不消、腹满泄泻、恶心哎吐、食欲不振、乳汁郁积、***胀痛等病症;
山楂,性味:酸甘、微温,无毒,具有消食积、化滞瘀之功效,用于治疗饮食积滞、脘腹胀痛、泄泻痢疾、血瘀痛经、闭经、产后腹痛、恶露不尽;
白术,性味:味苦、甘、性温,具有健脾益气、燥湿利水、止汗、安胎之功效,用于治疗脾气虚弱、神疲乏力、食少少腹胀、大便溏薄、水饮内停、小便不利、水肿、痰饮眩晕、温痹酸痛、气虚自汗、胎动不安;
川芎,性味:辛、温,具有行气开郁、法风燥湿、活血止痛之功效,用于治疗风冷头痛旋晕、胁痛腹疼、寒痹筋挛、经闭、难产、产后瘀阻块痛、痈疽疮疡、***、瘕腹痛、胸胁刺痛、跌扑肿痛、风湿痹痛;
丹参,性味:苦、微温,具有活血祛瘀、安神宁心、排脓、止痛之功效,用于治疗心绞痛、***、痛经、经闭、血崩带下、症瘕、积聚、瘀血腹痛、骨节疼痛、惊悸不眠、恶疮肿毒;
桃仁,性味:苦甘、平,具有破血行瘀、润燥滑肠之功效,用于治疗经闭、症瘕、热病蓄血、风痹、疟疾、跌打损伤、瘀血肿痛、血燥便秘等症;
红花,性味:味辛、性温,具有活血能经、祛瘀止痛之功效,用于治疗经闭、痛经、产后瘀阻腹痛、胞痹心痛症瘕积聚、跌打损伤、关节疼痛、中风偏竣、斑疹等症;
三棱(醋制),性味:苦辛、平,具有破血、行气、消积、止痛之功效,用于治疗癥瘕积聚、气血凝滞、心腹疼痛、胁下胀疼、经闭、产后瘀血腹痛、跌打损伤,疮肿坚硬;
莪术,性味: 味辛、苦、性温,具有行气破血、消积止痛之功效,用于治疗血气心痛、饮食积滞、脘腹胀痛、血滞经闭、痛经、症瘕瘤痞块、跌打损伤等症;
穿山甲,性味:味咸;性微寒,具有活血散结、通经下乳、消痈溃坚之功效,用于治疗血瘀经闭、癥瘕、风湿痹痛、乳汁不下、痈肿、瘰疬等症;
鳖甲,性味:味咸、性微寒,具有滋阴清热、潜阳熄风、软坚散结之功效,用于治疗阴虚发热、劳热骨蒸、热病伤阴、虚风内动、小作惊痫、久疟、疟母、癥瘕、经闭;
龟板,性味:甘、咸、寒,具有滋阴潜阳、益肾强骨、养血补心、退虚热之功效,用于治疗肾阴不足、骨蒸劳热、腰膝赓弱、心虚健忘、遗精、崩漏带下、小儿卤门不合、久嗽、久痢、久疟;
莱菔子,性味:味辛、甘、性平,具有消食导滞、降气化痰之功效,用于治疗食积气滞、脘腹胀满、腹泻、下痢后重、咳嗽多痰、气逆喘满;
青皮,性味: 苦、辛、温,具有疏肝破气、消积化滞之功效,用于治疗肝郁气滞之胁肋胀痛、***胀痛、乳核、乳痈、疝气疼痛、食积气滞之胃脘胀痛、以及气滞血瘀所至的症瘕积聚、久疟癖块等症;
青木香,性味:辛、苦、性寒,小毒,具有行气止痛、解毒消肿、平肝降压之功效,用于治疗胸胁院腹疼痛、疝气痛、肠炎、下痢腹痛、咳嗽痰喘、蛇虫咬伤、痈肿疔疮、湿疹、皮肤瘙痒、高血压病;
薤白,性味:辛、苦、温,具有通阳散结、行气导滞之功效,用于治疗胸痹疼痛、痰饮咳喘、泄痢后重;
香橼,性味:辛、苦、酸、温,具有理气降逆、宽胸化痰之功效,用于治疗胸腹满闷、胁肋胀痛、咳嗽痰多;
焦槟榔,性味:苦、辛、温,具有消食导滞之功效,用于治疗食积不消、泻痢后重;
干姜,性味:味辛、性热,具有温中散寒、回阳通脉、温肺化饮之功效,用于治疗脘腹冷痛、呕吐、泄泻、亡阳厥逆、寒饮喘咳、寒湿痹痛等症;
姜黄,性味:辛苦、温,具有破血、行气、通经、止痛之功效,用于治疗心腹痞满胀痛、臂痛、症瘕、妇女血瘀经闭、产后瘀停腹痛、跌扑损伤、痈肿等症;
五灵脂,性味:味苦、甘、性温,具有活血止痛、化瘀止血、消积解毒之功效,用于治疗心腹血气诸痛、妇女闭经、产后瘀滞腹痛、崩漏下血、小儿疳积和蛇、蝎、蜈蚣咬伤等;
益母草,性味:味辛、苦、性微寒,具有活血调经、利尿消肿、清热解毒之功效,用于治疗***、经闭、胎漏难产、胞衣不上、产后血晕、瘀血腹痛、跌打损伤、小便不利、水肿、头号肿疮疡等症;
鸡血藤,性味:苦甘、温,具有活血、舒筋之功效,用于治疗腰膝酸痛、麻木瘫痪、***等症;
苏木,性味:甘咸、平,具有行血、破瘀、消肿、止痛之功效,用于治疗妇人血气心腹痛、经闭、产后瘀血胀痛喘急、痢疾、破伤风、痈肿、扑损瘀滞作痛等症;
当归,性味:性温、味甘辛, 具有补血和血、调经止痛、润燥滑肠之功效,用于治疗血虚、面色萎黄、眩晕心悸、血虚、或兼有瘀滞的***、经闭、痛经、虚寒性腹痛、冠心病心绞痛、风湿痹痛、跌打损伤;
血竭,性味:味甘;咸、性平,小毒,具有散瘀定痛、止血、生肌敛疮之功效,用于治疗跌打损伤、内伤瘀痛、痛经、产后瘀阻腹痛、外伤出血不止、瘰疬、臁疮溃久不合及痔疮;
赤芍,性味:苦、微寒,具有清热凉血、活血祛瘀之功效,用于治疗温毒发斑、吐血衄血、肠风下血、目赤肿痛、痈肿疮疡、闭经、痛经、崩带淋浊、瘀滞胁痛、疝瘕积聚、跌扑损伤。
本发明药物是基于中医治疗气滞血瘀、肌瘤囊肿病证的原则,从药理作用及其作用机制认为:就气滞血瘀、肌瘤囊肿病证,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述气滞血瘀、肌瘤囊肿病证的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种治疗气滞血瘀、肌瘤囊肿病证的丸剂药物,其特征在于,所述药物的各个组分及其其质量份比如下所示:
陈皮80g、 枳实(炒)90g、茵陈120g、木香90g、香附(炒)120g、枳壳80g、郁金120g、神曲120g、沉香36g、茯苓120g、乌药120g、川楝子120g、佛手80g、麦芽120g、山楂80g、白术120g、川芎90g、丹参120g、桃仁120g、红花90g、三棱(醋制)120g、莪术120g、穿山甲80g、鳖甲250g、龟板260g、莱菔子80g、青皮115g、青木香80g、薤白80g、香橼45g、焦槟榔70g、干姜80g、姜黄120g、五灵脂120g、益母草250g、鸡血藤200g、苏木120g、当归120g、血竭12g、赤芍90g。
实施例2:
一种治疗气滞血瘀、肌瘤囊肿病证的丸剂药物,其特征在于,所述药物的各个组分及其其质量份比如下所示:
陈皮90g、 枳实(炒)100g、茵陈140g、木香100g、香附(炒)140g、枳壳90g、郁金140g、神曲140g、沉香42g、茯苓140g、乌药140g、川楝子140g、佛手90g、麦芽140g、山楂90g、白术140g、川芎90g、丹参140g、桃仁140g、红花100g、三棱(醋制)140g、莪术140g、穿山甲90g、鳖甲280g、龟板280g、莱菔子90g、青皮130g、青木香90g、薤白90g、香橼50g、焦槟榔80g、干姜90g、姜黄140g、五灵脂140g、益母草280g、鸡血藤230g、苏木140g、当归140g、血竭13g、赤芍100g。
实施例3:
一种治疗气滞血瘀、肌瘤囊肿病证的丸剂药物,其特征在于,所述药物的各个组分及其其质量份比如下所示:
陈皮100g、 枳实(炒)120g、茵陈160g、木香120g、香附(炒)160g、枳壳100g、郁金160g、神曲160g、沉香50g、茯苓160g、乌药160g、川楝子160g、佛手100g、麦芽160g、山楂100g、白术160g、川芎100g、丹参160g、桃仁160g、红花120g、三棱(醋制)160g、莪术160g、穿山甲100g、鳖甲320g、龟板320g、莱菔子100g、青皮150g、青木香100g、薤白100g、香橼60g、焦槟榔90g、干姜100g、姜黄160g、五灵脂160g、益母草320g、鸡血藤260g、苏木160g、当归160g、血竭15g、赤芍120g。
典型病例
经临床诊断治疗气滞血瘀、肌瘤囊肿病证患者共1100例,年龄为42岁以上的560例,只有540例为42岁以下。1100例患者中痊愈的850例,显效的250例,总有效率达100%。
Claims (3)
1.一种治疗气滞血瘀、肌瘤囊肿病证的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
陈皮30~100g、 枳实(炒)50~120g、茵陈60~160g、木香30~120g、香附(炒)80~160g、枳壳30~100g、郁金80~160g、神曲100~160g、沉香30~50g、茯苓100~160g、乌药80~160g、川楝子80~160g、佛手30~100g、麦芽100~160g、山楂30~100g、白术100~160g、川芎50~100g、丹参80~160g、桃仁80~160g、红花50~120g、三棱(醋制)80~160g、莪术80~160g、穿山甲30~100g、鳖甲100~320g、龟板90~320g、莱菔子50~100g、青皮50~150g、青木香30~100g、薤白50~100g、香橼30~60g、焦槟榔30~90g、干姜30~100g、姜黄50~160g、五灵脂50~160g、益母草150~320g、鸡血藤150~260g、苏木50~160g、当归80~160g、血竭10~15g、赤芍40~120g。
2.根据权利要求1所述的治疗气滞血瘀、肌瘤囊肿病证的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
陈皮40~90g、 枳实(炒)60~100g、茵陈70~140g、木香40~100g、香附(炒)90~140g、枳壳40~90g、郁金90~140g、神曲115~140g、沉香40~42g、茯苓115~140g、乌药90~140g、川楝子90~140g、佛手40~90g、麦芽115~140g、山楂40~90g、白术115~140g、川芎60~90g、丹参90~140g、桃仁90~140g、红花60~100g、三棱(醋制)90~140g、莪术90~140g、穿山甲40~90g、鳖甲115~280g、龟板100~280g、莱菔子60~90g、青皮60~130g、青木香40~90g、薤白60~90g、香橼40~50g、焦槟榔40~80g、干姜40~90g、姜黄60~140g、五灵脂60~140g、益母草170~280g、鸡血藤170~230g、苏木60~140g、当归90~140g、血竭11~13g、赤芍50~100g。
3.根据权利要求1至2所述的治疗气滞血瘀、肌瘤囊肿病证的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
陈皮80g、枳实(炒)90g、茵陈120g、木香90g、香附(炒)120g、枳壳80g、郁金120g、神曲120g、沉香36g、茯苓120g、乌药120g、川楝子120g、佛手80g、麦芽120g、山楂80g、白术120g、川芎90g、丹参120g、桃仁120g、红花90g、三棱(醋制)120g、莪术120g、穿山甲80g、鳖甲250g、龟板260g、莱菔子80g、青皮115g、青木香80g、薤白80g、香橼45g、焦槟榔70g、干姜80g、姜黄120g、五灵脂120g、益母草250g、鸡血藤200g、苏木120g、当归120g、血竭12g、赤芍90g。
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CN109364231A (zh) * | 2018-12-21 | 2019-02-22 | 彭秀荣 | 一种用于治疗气滞、血滞、食滞症状的中药及其制备方法 |
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CN109364231A (zh) * | 2018-12-21 | 2019-02-22 | 彭秀荣 | 一种用于治疗气滞、血滞、食滞症状的中药及其制备方法 |
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