CN105770733A - 一种治疗心绞痛的新型中药组合物及其制备方法 - Google Patents
一种治疗心绞痛的新型中药组合物及其制备方法 Download PDFInfo
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- CN105770733A CN105770733A CN201610162843.0A CN201610162843A CN105770733A CN 105770733 A CN105770733 A CN 105770733A CN 201610162843 A CN201610162843 A CN 201610162843A CN 105770733 A CN105770733 A CN 105770733A
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Abstract
本发明属于中医药技术领域,目的是根据中医对心绞痛的认识机理而提供的一种治疗心绞痛的新型中药组合物,所述中药组合物的各个组分及其质量份比如下:石菖蒲5~10g、薤白8~16g、丹参8~16g、牡蛎15~30g、川芎5~12g、瓜蒌皮6~9g、延胡索8~16g、青皮5~16g、陈皮3~12g、枳实3~12g、灵芝6~16g、枳壳3~10g、沉香3~7g、广木香3~12g、香附7.5~16g、乌药8~16g、川楝子3~10g、天仙藤6~10g、香橼3~6g、九香虫3~9g、郁金8~16g、姜黄5~16g、炙乳香3~10g、当归8~16g、炙没药5~16g、鸡血藤10~16g、土鳖虫3~9g、穿山甲3~9g、血竭1~1.5g;本发明提供的药物是一个很好的中药组方。
Description
技术领域
本发明涉及中医药技术领域,具体涉及一种治疗心绞痛的新型中药组合物,特别是供心绞痛患者使用的新型中药组合物及其制备方法的领域。
背景技术
心绞痛(anginapectoris)是冠状动脉供血不足,心肌急剧的暂时缺血与缺氧所引起的以发作性胸痛或胸部不适为主要表现的临床综合征。心绞痛是心脏缺血反射到身体表面所感觉的疼痛,特点为前胸阵发性、压榨性疼痛,可伴有其他症状,疼痛主要位于胸骨后部,可放射至心前区与左上肢,劳动或情绪激动时常发生,每次发作持续3~5分钟,可数日一次,也可一日数次,休息或用硝酸酯类制剂后消失。本病多见于男性,多数40岁以上,劳累、情绪激动、饱食、受寒、阴雨天气、急性循环衰竭等为常见诱因。
那么,就如何找到一种可有效治疗心绞痛的新型中药组合物,是我们目前急需要解决的问题。
发明内容
随着我国中医中药学的不断发展,在治疗心绞痛上,人们逐渐意识到了中医治疗上述心绞痛的优点,且在治疗过程中毒副作用小、费用低等优势,针对现有西医治疗上述心绞痛的现状,本发明的目的是在于提供一种治疗心绞痛的新型中药组合物,以解决心绞痛患者早日恢复健康的问题。该药物是以常见的中药为原料,具有见效快、疗效显著等特点,并可有效治疗上述心绞痛一证。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种治疗心绞痛的新型中药组合物及其制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
石菖蒲5~10g、薤白8~16g、丹参8~16g、牡蛎15~30g、川芎5~12g、瓜蒌皮6~9g、延胡索8~16g、青皮5~16g、陈皮3~12g、枳实3~12g、灵芝6~16g、枳壳3~10g、沉香3~7g、广木香3~12g、香附7.5~16g、乌药8~16g、川楝子3~10g、天仙藤6~10g、香橼3~6g、九香虫3~9g、郁金8~16g、姜黄5~16g、炙乳香3~10g、当归8~16g、炙没药5~16g、鸡血藤10~16g、土鳖虫3~9g、穿山甲3~9g、血竭1~1.5g。
一种治疗心绞痛的新型中药组合物及其制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
石菖蒲6~9g、薤白10~14g、丹参10~14g、牡蛎20~26g、川芎8~11g、瓜蒌皮6~8g、延胡索10~14g、青皮10~14g、陈皮8~11g、枳实8~11g、灵芝10~14g、枳壳7~9g、沉香4~6g、广木香8~11g、香附10~14g、乌药10~14g、川楝子6~9g、天仙藤7~9g、香橼4~5.5g、九香虫6~8g、郁金10~14g、姜黄10~14g、炙乳香6~9g、当归10~14g、炙没药10~14g、鸡血藤11~14g、土鳖虫5~8g、穿山甲5~8g、血竭1~1.2g。
一种治疗心绞痛的新型中药组合物及其制备方法,其特征在于,所述“最佳方案”的中药组合物的各个组分及其质量份比如下所示:
石菖蒲8g、薤白13g、丹参13g、牡蛎23g、川芎10g、瓜蒌皮7g、延胡索13g、青皮13g、陈皮10g、枳实10g、灵芝13g、枳壳8g、沉香5g、广木香10g、香附13g、乌药13g、川楝子8g、天仙藤8g、香橼5g、九香虫7g、郁金13g、姜黄13g、炙乳香8g、当归13g、炙没药13g、鸡血藤13g、土鳖虫7g、穿山甲7g、血竭1g。
一种治疗心绞痛的新型中药组合物及其制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、将上述原料中药拣去杂质和粉尘后,按照质量份比共研为极细末待用;
B、按照传统制备中药胶囊剂的方法,将研磨好的极细末药物过筛后,放入药器中混合均匀,然后制备成胶囊(其胶囊锁合后总长度为23.3mm,药粉容量0.4~0.5g/粒),进而分装密封备用。
一种治疗心绞痛的新型中药组合物及其制备方法,其特征在于,所述服用方法为:视患者病情而定,可选择间歇给药或长效给药,以及选择白天或夜间投药法,如以每日二次服用,早晚各服一次,给药量3g/次,饭前服,服药1~25天,症状明显减轻或痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
石菖蒲,性味:味辛、苦、性微温,具有化痰开窍、化湿行气、祛风利痹、消肿止痛之功效,用于治疗热病神昏、痰厥、健忘、耳鸣、耳聋、脘腹胀痛、噤口痢、风湿痹痛、跌打损伤、痈疽疥癣等症;
薤白,性味:辛苦、温,具有理气、宽胸、通阳、散结之功效,用于治疗胸痹心痛彻背、脘痞不舒、干呕、泻痢后重、疮疖;
丹参,性味:味苦、性微寒,具有活血祛瘀、调经止痛、养血安神、凉血消痈之功效,用于治疗妇女***、痛经、经闭、产后瘀滞腹痛、心腹疼痛、症瘕积聚、热痹肿痛、跌打损伤、热入营血、烦躁不安、心烦失眠、痈疮肿毒等症;
牡蛎,性味:味咸、性微寒,具有平肝潜阳、重镇安神、软坚散结、收敛固涩之功效,用于治疗眩晕耳鸣、惊悸失眠、瘰疬瘿瘤、癥瘕痞块、自汗盗汗、遗精、崩漏、带下;
川芎,性味:辛、温,具有行气开郁、法风燥湿、活血止痛之功效,用于治疗风冷头痛旋晕、胁痛腹疼、寒痹筋挛、经闭、难产、产后瘀阻块痛、痈疽疮疡、***、瘕腹痛、胸胁刺痛、跌扑肿痛、风湿痹痛等症;
瓜蒌皮,性味:苦、寒,具有清化热痰、利气宽胸之功效,用于治疗痰热咳嗽、胸闷胁痛;
延胡索,性味:辛、苦、温,无毒,具有活血、散瘀、理气、止痛之功效,用于治疗心腹腰膝诸痛、***、症瘕、崩中、产后血晕、恶露不尽、跌打损伤;
青皮,性味:苦、辛、温,具有疏肝破气、消积化滞之功效,用于治疗肝郁气滞之胁肋胀痛、***胀痛、乳核、乳痈、疝气疼痛、食积气滞之胃脘胀痛、以及气滞血瘀所至的症瘕积聚、久疟癖块等症;
陈皮,性味:味辛、苦、性温,具有理气和中,燥湿化痰,利水通便的功效,用于脾胃不和、脘腹胀痛、不思饮食、呕吐哕逆、痰湿阻肺、咳嗽痰多、胸膈满闷、头目眩晕、水肿、小便不利、大便秘结、乳痈疥癣、中鱼蟹毒、酒毒等;
枳实,性味:苦、辛、寒,具有破气消积、化痰除痞之功效,用于治疗积滞内停、痞满胀痛、大便秘结、泻痢后重、结胸、胃下垂、子宫脱垂、脱肛;
灵芝,性味:甘、平,无毒,具有益气血、安心神、健脾胃之功效,用于治疗虚劳、心悸、失眠、头晕、神疲乏力、久咳气喘、冠心病、硅肺、肿瘤等症;
枳壳,性味:苦、酸、性微寒,具有理气宽胸;行滞消积之功效,用于治疗胸隔痞满、胁肋胀痛、食积不化、脘腹胀满、下痢后重、脱肛、子宫脱垂;
沉香,性味:辛苦、温,具有降气温中、暖肾纳气的功效,用于气逆喘息、呕吐呃逆、脘腹胀痛、腰膝虚冷、大肠虚秘、小便气淋、男子精冷;
广木香,性味:味辛、苦、性温,具有温中行气止痛、健脾消食导滞之功效,用于治疗胸痞胁痛、脘腹胀痛、痢疾后重、食积不化、呕吐泄泻、寒疝腹痛、水肿、脚气;
香附,性味:味辛、微寒,无毒,具有理气解郁、调经止痛、安胎之功效,用于治疗胁肋胀痛、***胀育、疝气疼痛、***、脘腹痞满疼痛、嗳气吞酸、呕恶、经行腹痛、崩漏带下、胎动不安、消化不良等症;
乌药,性味:辛、温,具有行气止痛、温肾散寒之功效,用于治疗胸胁满闷、脘腹胀痛、头痛、寒疝疼痛、痛经及产后腹痛、尿频、遗尿等症;
川楝子,性味:苦、寒,有小毒,具有疏肝泄热、行气止痛、杀虫之功效,用于治疗脘腹胁肋疼痛、疝气疼痛、虫积腹痛、头癣等病症;
天仙藤,性味:苦、温,具有行气活血、利水消肿、解毒之功效,用于治疗胃痛、疝气痛、妊娠水肿、产后血气腹痛、蛇虫咬伤等病症;
香橼,性味:辛、苦、酸、温,具有理气降逆、宽胸化痰之功效,用于治疗胸腹满闷、胁肋胀痛、咳嗽痰多;
九香虫,性味:味咸、性温,具有行气止痛、温肾壮阳之功效,用于治疗肝胃不和或寒郁中焦所致的胸胁胃脘胀痛,以及坚阳不足之腰痛、阳痿;
郁金,性味:味辛、苦、性寒,具有活血止能、行气解郁、清心凉血、疏肝利胆之功效,用于治疗胸腹胁肋诸痛、妇女痛经、经闭、症瘕结块、热病神昏、癫狂、惊痫、吐血、衄备、血淋、砂淋、黄疸等症;
姜黄,性味:味苦、辛、性温,具有破血行气、通经止痛之功效,用于治疗血瘀气滞诸证、胞腹胁痛、妇女痛经、闭经、产后瘀滞腹痛、风湿痹痛、跌打损伤、痈肿等症;
炙乳香,性味:味辛、苦、微温,具有活血行气、通经止痛、消肿生肌之功效,用于治疗心腹疼痛、风湿痹痛、经闭痛经、跌打瘀痛、痈疽肿毒、肠痈、疮溃不敛;
当归,性味:性温、味甘辛,具有补血和血、调经止痛、润燥滑肠之功效,用于治疗血虚、面色萎黄、眩晕心悸、血虚、或兼有瘀滞的***、经闭、痛经、虚寒性腹痛、冠心病心绞痛、风湿痹痛、跌打损伤等症;
炙没药,性味:味苦、性平,具有散瘀止痛,外用消肿生肌之功效,用于治疗跌打淤血肿痛、痈疽肿痛、胸腹诸痛,外用治疮口久不收敛;
鸡血藤,性味:味苦、微甘、性温,具有活血舒筋、养血调经之功效,用于治疗手足麻木、肢体瘫痪、风湿痹痛、妇女有经不调、痛经、闭经;
土鳖虫,性味:咸、寒,有小毒,具有破瘀血、续筋骨之功效,用于治疗筋骨折伤、瘀血经闭、症瘕痞块;
穿山甲,性味:味咸、微凉,具有消肿溃痈、搜风活络、通经下乳之功效,用于治疗痈疽疮肿、风寒湿痹、月经停闭、乳汁不通,外用止血;
血竭,性味:味甘、咸、性平,小毒,具有散瘀定痛、止血、生肌敛疮之功效,用于治疗跌打损伤、内伤瘀痛、痛经、产后瘀阻腹痛、外伤出血不止、瘰疬、臁疮溃久不合及痔疮。
本发明药物是基于中医治疗心绞痛的辨病与辨证相结合的原则,从药理作用及作用机制认为:就心绞痛一证,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述心绞痛的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种治疗心绞痛的新型中药组合物,其特征在于,所述中药组合物的各个组分及质量份比如下所示:
石菖蒲8g、薤白13g、丹参13g、牡蛎23g、川芎10g、瓜蒌皮7g、延胡索13g、青皮13g、陈皮10g、枳实10g、灵芝13g、枳壳8g、沉香5g、广木香10g、香附13g、乌药13g、川楝子8g、天仙藤8g、香橼5g、九香虫7g、郁金13g、姜黄13g、炙乳香8g、当归13g、炙没药13g、鸡血藤13g、土鳖虫7g、穿山甲7g、血竭1g。
实施例2:
一种治疗心绞痛的新型中药组合物,其特征在于,所述中药组合物的各个组分及质量份比如下所示:
石菖蒲9g、薤白14g、丹参14g、牡蛎26g、川芎11g、瓜蒌皮8g、延胡索14g、青皮14g、陈皮11g、枳实11g、灵芝14g、枳壳9g、沉香6g、广木香11g、香附14g、乌药14g、川楝子9g、天仙藤9g、香橼5.5g、九香虫8g、郁金14g、姜黄14g、炙乳香9g、当归14g、炙没药14g、鸡血藤14g、土鳖虫8g、穿山甲8g、血竭1.2g。
实施例3:
一种治疗心绞痛的新型中药组合物,其特征在于,所述中药组合物的各个组分及质量份比如下所示:
石菖蒲10g、薤白16g、丹参16g、牡蛎30g、川芎12g、瓜蒌皮9g、延胡索16g、青皮16g、陈皮12g、枳实12g、灵芝16g、枳壳10g、沉香7g、广木香12g、香附16g、乌药16g、川楝子10g、天仙藤10g、香橼6g、九香虫9g、郁金16g、姜黄16g、炙乳香10g、当归16g、炙没药16g、鸡血藤16g、土鳖虫9g、穿山甲9g、血竭1.5g。
典型病例:
经临床诊断治疗心绞痛患者共203例,年龄为49岁以上的130例,只有73例为49岁以下。200例患者中痊愈的165例,显效的38例,总有效率达100%。经治疗后,症状明显减轻或痊愈。
Claims (3)
1.一种治疗心绞痛的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
石菖蒲5~10g、薤白8~16g、丹参8~16g、牡蛎15~30g、川芎5~12g、瓜蒌皮6~9g、延胡索8~16g、青皮5~16g、陈皮3~12g、枳实3~12g、灵芝6~16g、枳壳3~10g、沉香3~7g、广木香3~12g、香附7.5~16g、乌药8~16g、川楝子3~10g、天仙藤6~10g、香橼3~6g、九香虫3~9g、郁金8~16g、姜黄5~16g、炙乳香3~10g、当归8~16g、炙没药5~16g、鸡血藤10~16g、土鳖虫3~9g、穿山甲3~9g、血竭1~1.5g。
2.根据权利要求1所述的治疗心绞痛的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
石菖蒲6~9g、薤白10~14g、丹参10~14g、牡蛎20~26g、川芎8~11g、瓜蒌皮6~8g、延胡索10~14g、青皮10~14g、陈皮8~11g、枳实8~11g、灵芝10~14g、枳壳7~9g、沉香4~6g、广木香8~11g、香附10~14g、乌药10~14g、川楝子6~9g、天仙藤7~9g、香橼4~5.5g、九香虫6~8g、郁金10~14g、姜黄10~14g、炙乳香6~9g、当归10~14g、炙没药10~14g、鸡血藤11~14g、土鳖虫5~8g、穿山甲5~8g、血竭1~1.2g。
3.根据权利要求1至2所述的治疗心绞痛的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
石菖蒲8g、薤白13g、丹参13g、牡蛎23g、川芎10g、瓜蒌皮7g、延胡索13g、青皮13g、陈皮10g、枳实10g、灵芝13g、枳壳8g、沉香5g、广木香10g、香附13g、乌药13g、川楝子8g、天仙藤8g、香橼5g、九香虫7g、郁金13g、姜黄13g、炙乳香8g、当归13g、炙没药13g、鸡血藤13g、土鳖虫7g、穿山甲7g、血竭1g。
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CN105944042A (zh) * | 2016-07-25 | 2016-09-21 | 毛德西 | 防治冠心病的中药 |
CN106166266A (zh) * | 2016-10-02 | 2016-11-30 | 四川兴聚焦医药科技有限责任公司 | 一种用于治疗哮喘的中药组合物及制备方法 |
CN106267113A (zh) * | 2016-10-01 | 2017-01-04 | 四川兴聚焦医药科技有限责任公司 | 一种治疗白脉病的中药组合物及其制备方法 |
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CN106166266A (zh) * | 2016-10-02 | 2016-11-30 | 四川兴聚焦医药科技有限责任公司 | 一种用于治疗哮喘的中药组合物及制备方法 |
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