CN106236855A - A kind of compositions of assisting in reducing blood sugar - Google Patents
A kind of compositions of assisting in reducing blood sugar Download PDFInfo
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Abstract
The invention discloses the compositions of a kind of assisting in reducing blood sugar, described compositions includes Fructus Momordicae charantiae extract 450 500 weight portion, Radix Et Rhizoma Fagopyri Tatarici extract 150 250 weight portion, Herb Gynostemmae Pentaphylli extract 150 250 weight portion, Folium Mori extract 200 250 weight portion, Fructus Corni extract 100 150 weight portion, Semen Trigonellae extract 100 200 weight portion and Radix Astragali extract 10 20 weight portion, and said composition has good auxiliary hyperglycemic effect.Present invention also offers preparation containing said composition and preparation method thereof.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to the Chinese medicine composition of a kind of assisting in reducing blood sugar.
Background technology
Diabetes are a kind of ancient diseases (ancients are called " quenching one's thirst "), but in economic and underdeveloped China, seldom
Since someone suffers from diabetes, reform and opening-up, the living standard of most compatriots is improved or improves, and seldom hears in the past
Diabetes develop rapidly with unprecedented speed, have become the main sick kind of China one, and diabetes are a kind of endocrine metabolisms
Disease, it is owing to internal insulin is absolute or relative deficiency, causes the metabolism disorder of sugar, fat, protein.In early days without disease
Shape, may occur in which " three-many-one-little " symptom when blood glucose is too high, i.e. polyuria, polydipsia, polyphagia and lose weight, and occurs tired, unable
And the debilitating symptoms such as lassitude.Diabetes can cause multiple complications, brings great inconvenience to the life of people.Mesh
Before, China's diabetics more than 40,000,000, additionally, also several ten million people be " carbohydrate tolerance reduction person " be potential diabetes
Patient, so, onset diabetes form is the severeest.
The category that the diabetes spp traditional Chinese medical science " is quenched one's thirst ", the most uncomfortable by feelings will, to overwork, eating and drinking without temperance, polyphagia is pungent, fertile
Greasy, the thing of spirituosity, stagnant middle Jiao of harmony, cause transporting and transforming function of the spleen and stomach not normal, make raw interior-heat, pent up dryness-transformation, scorching impairment of YIN, it is impossible to moisten lung
Kidney and send out for quenching one's thirst.The traditional Chinese medical science is divided into upper, middle and lower three to disappear quenching one's thirst.Thirsty polydipsia person disappears on being, belongs to lung；During polyphagia polyphagia person is
Disappear, belong to stomach；Polyuria or urine disappear under such as fat person being, belong to kidney.Its pathological change is based on the deficiency of YIN, scorching.Therefore use traditional Chinese medical science yin nourishing
Heat clearing away, replenishing QI to invigorate the spleen, the method treatment of tonifying the kidney to consolidate the essence, hit pathogenesis.
With the scientific level of present stage, diabetes cannot be cured, and investigation can only be had aobvious by glycemic control to normal range
Show: diabetics is in the urgent need to coordinating medicine, stabilizing blood sugar, and the health food to human non-toxic's side effect, thus auxiliary
Hypoglycemic product is helped also to arise at the historic moment.Although present stage a lot of auxiliary hyperglycemic product is obtained for accreditation and the welcome of people,
But the health product of auxiliary hyperglycemic add Rich chromium yeast mostly that promote chromium content, because being biological raw material, relatively costly,
The patient needing long-term taking is caused great financial burden, so, the health-product market of auxiliary hyperglycemic still has certain
Vacancy, is badly in need of that irradiation hypoglycemic effect is good and the product of cheap applicable long-term taking.
Summary of the invention
For solving above-mentioned technical problem, an object of the present invention is to provide the compositions of a kind of assisting in reducing blood sugar,
It is good that said composition reduces hypoglycemic effect, and cheap.
The two of the purpose of invention are to provide the preparation containing said composition.
The three of the purpose of invention are to provide the preparation method of said preparation.
The above-mentioned purpose of the present invention is achieved through the following technical solutions:
The compositions of a kind of assisting in reducing blood sugar, said composition includes that Fructus Momordicae charantiae extract 450-500 weight portion, Radix Et Rhizoma Fagopyri Tatarici carry
Take thing 150-250 weight portion, Herb Gynostemmae Pentaphylli extract 150-250 weight portion, Folium Mori extract 200-250 weight portion, Fructus Corni carry
Take thing 100-150 weight portion, Semen Trigonellae extract 100-200 weight portion and Radix Astragali extract 10-20 weight portion.
Wherein, Fructus Momordicae charantiae extract: Fructus Momordicae charantiae (Momordica charania L.), for Cucurbitaceae Momordica annual herb
Plant, nature and flavor bitter cold, there is heat-clearing and toxic substances removing and nourish the effects such as strong, blood sugar lowering.
Radix Et Rhizoma Fagopyri Tatarici extract: Radix Et Rhizoma Fagopyri Tatarici belongs to Polygonaceae dicotyledon, is commonly called as Radix Et Rhizoma Fagopyri Tatarici, formal name used at school hull buckwheat, and Radix Et Rhizoma Fagopyri Tatarici happiness is cool
Refreshing, resistance to ridge is thin, is grown in high and cold mountain area more, and seed is edible, and Compendium of Material Medica is recorded, Radix Et Rhizoma Fagopyri Tatarici bitter in the mouth, and property is put down, cold.
Herb Gynostemmae Pentaphylli, for the dry herb of cucurbitaceous plant Herb Gynostemmae Pentaphylli.Bitter in the mouth, cold in nature, return lung, spleen, kidney channel.There is QI invigorating mend
Effect of spleen.Main containing saponin constituent, amino acids, flavone compound, trace element and polysaccharide etc..
Folium Mori extract: the Pharmacopoeia of the People's Republic of China one record: Folium Mori are moraceae plants Mulberry Morus alba L.
Dried leaves.Folium Mori are the plants of the medicine-food two-purpose that health ministry specifies, its sweet in the mouth, bitter, cold.Return lung, Liver Channel.
Fructus Corni extract: the Pharmacopoeia of the People's Republic of China one record: Fructus Corni is Cornaceae plant Fructus Corni
The drying and ripening sarcocarp of Cornus officinalis Sieb.et Zucc., acid, puckery, tepor.Return liver, kidney channel.
Semen Trigonellae extract: the Pharmacopoeia of the People's Republic of China one record: Semen Trigonellae is leguminous plant Semen Trigonellae
The dry mature seed of Trigonella foenum-graecum L..Hardship, temperature, return kidney channel.
The Radix Astragali, for the dry root of leguminous plant Radix Astagali.Sweet in the mouth, warm in nature.Return lung, spleen channel, there is the merits such as invigorating QI to consolidate the body surface resistance
Effect.Begin to be loaded in Shennong's Herbal, be one of the most frequently used in motherland's medical science " strengthening the body resistance, invigorating the spleen and replenishing QI " medicine.
The compositions of the present invention selects the extract prepared by material of integration of edible and medicinal herbs to be raw material, nontoxic and auxiliary hyperglycemic
Effect is notable.
Have in some prior art literature and use the part material of the present invention to prepare the compositions of auxiliary hyperglycemic, but this
A little compositionss are extracted under identical conditions after being typically to mix all raw materials and are prepared.But the effective ingredient in each raw material with
The ability of dissolution under the conditions of is different.The present invention selects different solvents to extract respectively, with the extraction of different solvents dissolution
Thing is raw material, makes the medical value of Chinese crude drug give full play to, and the active constituent content of product is higher.And the combination of prior art
Thing improves sugar and lipid metabolism usually through chromium supplement, promotes impaired islets of langerhans and β cellular morphology, structure, the recovery of function, assists islets of langerhans
Element plays a role.But the absorbance that inorganic chromium is in body is relatively low, the impact on insulin active is less, and institute from food
The organic chromium being provided that is limited, and yeast has the ability of Rich in Trace Element, and inorganic chromium can change into organic chromium, improves human body
Availability to it.So the compositions of assisting in reducing blood sugar selects to add Rich chromium yeast mostly, but Rich chromium yeast price is held high
Expensive, production cost is high, and the price of product is the highest, for the diabetic needing long-term taking, will be the biggest bearing
Load.The present inventor obtains the compositions of the present invention through long-term research and development, prepares with common, cheap raw material
Obtain the product with notable assisting in reducing blood sugar, be suitable to long-term taking, the combination that some currently preferred embodiments of the present invention obtains
Thing, its assisting in reducing blood sugar and the product containing Rich chromium yeast are quite or more excellent.
As preferably, the compositions of this assisting in reducing blood sugar includes that Fructus Momordicae charantiae extract 450-480 weight portion, Radix Et Rhizoma Fagopyri Tatarici extract
Thing 200-250 weight portion, Herb Gynostemmae Pentaphylli extract 150-180 weight portion, Folium Mori extract 200-250 weight portion, Fructus Corni extract
Thing 120-150 weight portion, Semen Trigonellae extract 100-150 weight portion and Radix Astragali extract 15-20 weight portion.
As more excellent selection, said composition include Fructus Momordicae charantiae extract 480 weight portion, Radix Et Rhizoma Fagopyri Tatarici extract 200 weight portion,
Herb Gynostemmae Pentaphylli extract 180 weight portion, Folium Mori extract 225 weight portion, Fructus Corni extract 125 weight portion, Semen Trigonellae extract
150 weight portions and Radix Astragali extract 15 weight portion；Or said composition includes Fructus Momordicae charantiae extract 450 weight portion, Radix Et Rhizoma Fagopyri Tatarici extract
220 weight portions, Herb Gynostemmae Pentaphylli extract 150 weight portion, Folium Mori extract 200 weight portion, Fructus Corni extract 150 weight portion, calabash
Reed bar extract 150 weight portion and Radix Astragali extract 15 weight portion.
The extract of the present invention all can be through commercially available acquisition, it is also possible to oneself is prepared；Wherein for water extract, extract
Method is: medical material adds 6-10 times of soak by water, decocts repeatedly, and decocting liquid filters, merging filtrate, filtrate reduced in volume, is dried, sieves
Obtain；
For ethanol extraction, extracting method is: by medical material 5-10 times amount alcohol reflux repeatedly, and extracting solution is filtered
Crossing, merging filtrate, concentrated filtrate reclaims ethanol, obtains clear paste, is dried, sieves and get final product.
Present invention also offers the preparation of compositions containing above-mentioned assisting in reducing blood sugar, described preparation be capsule,
Tablet, pill or granule.
Above preparation can be prepared as, by the compositions of the present invention being arranged in pairs or groups with conventional formulation adjuvant, the oral agents commonly used
Type, includes but not limited to capsule, tablet, granule, pill etc.；It is preferably granule.
Conventional formulation adjuvant of the present invention, includes but not limited to filler, disintegrating agent, lubricant, suspending agent, bonding
Agent, sweeting agent, correctives, preservative, substrate etc..Filler includes: starch, pregelatinized Starch, lactose, mannitol, chitin,
Microcrystalline Cellulose, sucrose etc.；Disintegrating agent includes: starch, pregelatinized Starch, microcrystalline Cellulose, carboxymethyl starch sodium, the poly-second of crosslinking
Alkene pyrrolidone, low-substituted hydroxypropyl cellulose, cross-linking sodium carboxymethyl cellulose etc.；Lubricant includes: magnesium stearate, dodecyl
Sodium sulfate, Pulvis Talci, silicon dioxide etc.；Suspending agent includes: polyvinylpyrrolidone, microcrystalline Cellulose, sucrose, agar, hydroxypropyl
Ylmethyl cellulose etc.；Binding agent includes: starch slurry, polyvinylpyrrolidone, hydroxypropyl methyl cellulose etc.；Sweeting agent bag
Include: saccharin sodium, Aspartane, sucrose, cyclamate, enoxolone etc.；Correctives includes: sweeting agent and various essence；Preservative
Including: parabens, benzoic acid, sodium benzoate, sorbic acid and its esters, benzalkonium bromide, fixed, the eucalyptus oil of acetic acid chloroethene etc.；Base
Matter includes: PEG6000, PEG4000, insect wax etc..
The present invention also provides for the method for the granular preparation of a kind of compositions prepared containing above-mentioned assisting in reducing blood sugar, the party
The steps such as method includes following sieving, mixes, granulation.
Method as claimed in claim 7, it is characterised in that sieve and selected 80 mesh sieves.
Method as claimed in claim 7, it is characterised in that during granulation with 75% ethanol soft material, then by soft material mistake
20 mesh sieves make preparation granules.
Present invention also offers above-mentioned composition application in the health product of preparation treatment auxiliary hyperglycemic.
The beneficial effects of the present invention is: choose Fructus Momordicae charantiae, Radix Et Rhizoma Fagopyri Tatarici, Herb Gynostemmae Pentaphylli, Folium Mori, Fructus Corni, Semen Trigonellae and the Radix Astragali
The raw material of these integration of edible and medicinal herbs, with respective extract as raw material, carries out organic assembling with specific proportioning, the compositions tool obtained
Have a notable assisting in reducing blood sugar effect, and a various low in raw material price, through reasonable compatibility can obtain with containing Rich chromium yeast
The most excellent effect.
Detailed description of the invention
Below by way of detailed description of the invention, the foregoing of the present invention is described in further detail.But should be by
This is interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to Examples below.All technology realized based on foregoing of the present invention
Belong to the scope of the present invention.
Table 1 formula
Raw material sources:
Fructus Momordicae charantiae extract: Rui Fen bio tech ltd, Beijing Extraction solvent is ethanol
Radix Et Rhizoma Fagopyri Tatarici extract: Rui Fen bio tech ltd, Beijing Extraction solvent is water
Herb Gynostemmae Pentaphylli extract: Rui Fen bio tech ltd, Beijing Extraction solvent is ethanol
Folium Mori extract: Rui Fen bio tech ltd, Beijing Extraction solvent is ethanol
Fructus Corni extract: Rui Fen bio tech ltd, Beijing Extraction solvent is ethanol
Semen Trigonellae extract；Rui Fen bio tech ltd, Beijing Extraction solvent is water
Radix Astragali extract: Rui Fen bio tech ltd, Beijing Extraction solvent is water
Embodiment 1
Formula according to the embodiment 1 shown in table 1 weighs and meets company standard through the qualified Fructus Momordicae charantiae extract of inspection, Radix Et Rhizoma Fagopyri Tatarici
Wheat extract, Herb Gynostemmae Pentaphylli extract, Folium Mori extract, Fructus Corni extract, Semen Trigonellae extract, Radix Astragali extract cross 80 respectively
It is standby that mesh sieve obtains fine powder.Separately weigh starch 14.80kg, dextrin 6.51kg, that stevioside 0.36kg crosses 80 mesh sieves is standby.
Radix Astragali extract fine powder and stevioside fine powder mixing 15min are obtained mixed powder 1；Take Fructus Corni extract fine powder with
Mixed powder 1 mixes 15min, obtains mixed powder 2；Take Fructus Momordicae charantiae extract fine powder, Radix Et Rhizoma Fagopyri Tatarici extract fine powder, Folium Mori extract fine powder,
Semen Trigonellae extract fine powder, starch dust, dextrin fine powder mix 25min with mixed powder 2, obtain total mixed powder.
By total mixed powder with 75% ethanol (food grade), soft material processed, obtain soft material；Soft material is crossed 20 mesh and makes granule,
Wet granular；Dry, granulate: by wet granular at 65 DEG C of-70 DEG C of dry 40-60min, to moisture≤5%, cross 20 mesh sieve granulate,
Conforming particle；It is packaged into 3g/ bag.
Embodiment 2-3
Formula according to embodiment 2-3 shown in table 1 is prepared as described in Example 1.
Embodiment 4
(1) weigh Fructus Momordicae charantiae 1kg, Radix Et Rhizoma Fagopyri Tatarici 2kg, Folium Mori 1kg, Semen Trigonellae 1kg, Fructus Corni 2kg, add aforementioned medical material gross weight
The water (i.e. 105kg) of 15 times decocts 3h, filters to obtain decoction liquor；
(2) decoction liquor is concentrated into the extractum that relative density is 1.20 (measuring under the conditions of 60 DEG C), is spray-dried, then adds 7g
Rich chromium yeast, mixing, granule processed, it is dried, granulate；By wet granular at 65 DEG C of-70 DEG C of dry 40-60min, to moisture≤5%, mistake
20 mesh sieve granulate, obtain conforming particle；It is packaged into 3g/ bag.
Embodiment 5 auxiliary hyperglycemic function zoopery
1.1 samples: the sample 1 prepared by embodiment 1；The sample 2 prepared by embodiment 4, specification 3g/ bag, people is oral to push away
Recommending dosage is everyone (adult) every day 2 times, each 1 bag, and adult's body weight press 60kg calculating, and equivalent dosage is 100mg/kgBW.
1.2 laboratory animals: the SPF level healthy adult SD kind selecting Guangxi Medical University's Experimental Animal Center breeding is male greatly
Mus, body weight is l50 ± 20 gram, laboratory animal production licence number: SCK (osmanthus) 2009-0002, the Quality of Experimental Animals quality certification
Number: 0001299.
1.3 zoopery room environmental conditions: Animal Lab. is barrier system, use credit number: SYXK (osmanthus) 2011-
0005.Animal experiment temperature: 22～25 DEG C, relative humidity: 55～70%.
1.4 dosage choice and tested material give mode: recommend consumption according to the human body of this sample, if 250,500,
The test group of 1000mg/kg BW (be respectively equivalent to human body and recommend the 2.5 of consumption, 5,10 times) 3*2 dosage, sets one simultaneously
Model group matched group and a blank group, separately set given the test agent group (high dose) and the matched group of an intact animal, often
Organize 15 rats.Weigh respectively the granule 2.5 of sample 1 and 2,5.0,10g, respectively add pure water to 100ml, mix, be made into 25,50,
100mg/mL strength solution, gives corresponding agent gavage respectively, and the given the test agent group of intact animal gives 100mg/mL strength solution,
Gavage volume is lmg/100g Bw, and model control group, blank group and intact animal's matched group give isopyknic pure water,
Every day gavage once, continuous gavage 33 days.
1.5 key instruments and reagent:
Instrument: Luo Kang brilliance entirely moulds blood glucose meter, electronic analytical balance etc..
Reagent: blood sugar test paper, lot number is 470965 etc..
1.6 experimental technique
1.6.1 blood glucose model blood sugar lowering test
The state's food medicine issued according to State Food and Drug Administration supervises guarantorization [2012] 107 about printing and distributing antioxidation
Adnexa 3 auxiliary hyperglycemic function evaluation methodology in the notice of 9 health care evaluation methodologys such as function evaluation methods, uses dynamic
Thing testing program two alloxan induced insulin opposing sugar/hyperlipoidemia method.Healthy male rat, gives general
Logical maintenance expects to adapt to raise 5 days, and fasting 4 hours, the ophthalmic corner of the eyes takes blood, measures to (i.e. 0 hour) blood glucose value before glucose, gives
0.5,2 hours blood glucose value after 2.5g/kgBW glucose, as this batch animal basic value.8 are divided with 0,0.5 hours blood glucose level
Individual group, i.e. 1 blank group, 1 model control group and 3*2 dosage group, often group 15.Blank group does not processes,
3*2 dosage group gavage gives variable concentrations given the test agent 1 and 2, and model control group gives same volume pure water, continuous 33 days.Respectively
Group gives to maintain material to raise, and after 1 week, model control group and 3 dosage groups change high thermal energy fodders, and feed is after 3 weeks, model comparison
Group and 3 dosage fasting 24 hours (can't help water), give alloxan 104mg/kg BW lumbar injection, injection volume lmL/100g
Body weight.Continue to give high thermal energy fodder after injection to feed 5 days.Off-test, each treated animal fasting 4 hours, detection fasting glucose,
Carbohydrate tolerance, serum insulin and cholesterol (TG), triglyceride (TC) level.
Fasting glucose, carbohydrate tolerance test: each treated animal fasting 4 hours, measure fasting glucose i.e. to before glucose (0 hour)
Blood glucose value, dosage group gives variable concentrations given the test agent, and model control group gives same volume pure water, and blank group is not done and located
Reason, l is each group oral administration of glucose 2.5g/100g Bw after 5 minutes, measures to group blood glucose of 0.5,2 hours each after glucose
Value.If model control group 0.5 hours blood glucose value is more than or equal to 10mmol/L, or model control group 0.5 hour, 2 hours arbitrary
Time point blood glucose raises or Area under the curve of blood glucose raises, and compares with blank group, and difference has significance, it is determined that model sugar generation
Thank to disorderly establishment.On the premise of model is set up, given the test agent dosage group compares with model control group, and fasting glucose difference has system
Meaning learned by meter, i.e. judges that this given the test agent fasting glucose index result is positive；Given the test agent dosage group compares with model control group,
After to glucose, 0.5,2 hours any time point blood glucose declines statistically significant, or below 0,0.5,2 hours blood glucose curves
Long-pending reduction is statistically significant, i.e. judges that this given the test agent carbohydrate tolerance index result is positive.
Blood lipids index: each treated animal fasting 4 hours, detects serum cholesterol, triglyceride, if model control group serum gallbladder
Sterin or triglyceride is significantly raised many compares with blank group, difference has significance, it is determined that the establishment of model disorders of lipid metabolism.
On the premise of model is set up, many given the test agent dosage group compares with model control group, and serum cholesterol or triglyceride decline to be had
Statistical significance, can determine that this given the test agent blood fat reducing index is positive.
1.6.2 intact animal: select healthy adult animal, is grouped in being randomly divided into test sample by fasting 4 hours blood glucose level
Product group (high dose) and blank group, often 15 rats of group.Sample sets gives l00mg/mL concentration samples solution, gavage volume
For 1mL/100g BW, blank group gives isopyknic pure water, every day gavage once, continuous gavage 33 days, experiment terminates
Measure the fasting glucose (fasting 44 hours) of rat.
1.7 experimental data processing: use SPSS11.0 statistical software to carry out variance analysis statistical disposition.
1.8 results judge: an index positive in fasting glucose and carbohydrate tolerance binomial index, and blood fat is (T-CHOL, sweet
Oil three esters) without significantly raised, on intact animal's fasting glucose without impact, i.e. can determine that this given the test agent auxiliary hyperglycemic function moves
Thing experimental result is positive.
2 results
2.1
Table 2 is each carbohydrate tolerance test result organizing rat before testing
Note: under 0h, 0.5h, 2.5h blood glucose of each group and blood glucose, area is compared to each other, and there are no significant for difference (P > 0.05).
As seen from the above table, before test, between each group rat, under blood glucose and blood glucose, area discrepancy is without significance, and each group rat is real
Test front carbohydrate tolerance without being clearly distinguished from.
The carbohydrate tolerance test result of rat is respectively organized during table 3 off-test
Note: ## compares with blank group, and P < 0.01, * * compares with model group, P < 0.01, * compare with model group P <
0.05。
From upper table, after off-test, after gavage glucose, 0h, 0.5h, 2.5h blood glucose of model control group and blood
Sugar area under curve is higher than blank group, and 0.5h and 2 hours blood glucose values > 10mmol/L, have compared with blank group
The difference (P < 0.01) of highly significant, shows that hyperglycemia model is set up.After gavage glucose, 0h, 0.5h sample each dosage group
Blood glucose compare without significant difference (P > 0.05) with model control group, and be significantly lower than at the blood glucose value of 2h sample 1 each dosage group
Model control group (P < 0.01), difference highly significant；And sample 2 dosage group the highest, middle compares display difference with model control group,
But difference is not up to highly significant (P < 0.05)；Sample 1 each dosage group Area under the curve of blood glucose is less than model control group, and each dose
The difference of amount group has very significant (P < 0.01), and sample 2 only high dose group demonstrates variant (P < 0.05).Chinese medicine sample
Product are the most inconspicuous on the impact of fasting blood sugar, and sample 1 tool is significantly reduced the effect of blood glucose, and hypoglycemic effect is better than sample
Product 1.
2.2 samples blood fat on hyperglycemia model rat and the impact of insulin content
Each the group blood fat of rat, insulin content testing result at the end of table 4 experiment
Note: #, ## compare with blank group, respectively P < 0.05, P < 0.0l；*, * * compare with model control group, respectively P <
0.05、P<0.0l。
From table 4, at the end of experiment, the serum TC of model control group, TG content are higher than blank group, and difference
Tool.
Claims (10)
1. the compositions of an assisting in reducing blood sugar, it is characterised in that described compositions includes Fructus Momordicae charantiae extract 450-500 weight
Part, Radix Et Rhizoma Fagopyri Tatarici extract 150-250 weight portion, Herb Gynostemmae Pentaphylli extract 150-250 weight portion, Folium Mori extract 200-250 weight
Part, Fructus Corni extract 100-150 weight portion, Semen Trigonellae extract 100-200 weight portion and Radix Astragali extract 10-20 weight
Part.
2. the compositions of assisting in reducing blood sugar as claimed in claim 1, it is characterised in that described compositions includes that Fructus Momordicae charantiae extracts
Thing 450-480 weight portion, Radix Et Rhizoma Fagopyri Tatarici extract 200-250 weight portion, Herb Gynostemmae Pentaphylli extract 150-180 weight portion, Folium Mori extract
Thing 200-250 weight portion, Fructus Corni extract 120-150 weight portion, Semen Trigonellae extract 100-150 weight portion and astragalus extraction
Thing 15-20 weight portion.
3. the compositions of assisting in reducing blood sugar as claimed in claim 1, it is characterised in that described compositions includes that Fructus Momordicae charantiae extracts
Thing 480 weight portion, Radix Et Rhizoma Fagopyri Tatarici extract 200 weight portion, Herb Gynostemmae Pentaphylli extract 180 weight portion, Folium Mori extract 225 weight portion,
Fructus Corni extract 125 weight portion, Semen Trigonellae extract 150 weight portion and Radix Astragali extract 15 weight portion.
4. the compositions of assisting in reducing blood sugar as claimed in claim 1, it is characterised in that described compositions includes that Fructus Momordicae charantiae extracts
Thing 450 weight portion, Radix Et Rhizoma Fagopyri Tatarici extract 220 weight portion, Herb Gynostemmae Pentaphylli extract 150 weight portion, Folium Mori extract 200 weight portion,
Fructus Corni extract 150 weight portion, Semen Trigonellae extract 150 weight portion and Radix Astragali extract 15 weight portion.
5. one kind containing the preparation of the compositions of assisting in reducing blood sugar described in any one in claim 1-4, it is characterised in that
Described preparation is capsule, tablet, pill or granule.
6. require the preparation as described in 5 such as profit, it is characterised in that described preparation is granule.
7. the method preparing preparation described in claim 6, comprises the steps: to sieve, mixes, pelletizes.
8. method as claimed in claim 7, it is characterised in that sieve and selected 80 mesh sieves.
9. method as claimed in claim 7, it is characterised in that during granulation with 75% ethanol soft material, obtain soft material, by soft material
Cross 20 mesh sieves and make granule.
10. the application in the health product of preparation treatment auxiliary hyperglycemic of the compositions as described in claim 1-4 any one.
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| CN201610723929.6A CN106236855A (en) | 2016-08-25 | 2016-08-25 | A kind of compositions of assisting in reducing blood sugar |
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| CN201610723929.6A CN106236855A (en) | 2016-08-25 | 2016-08-25 | A kind of compositions of assisting in reducing blood sugar |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108420063A (en) * | 2018-03-20 | 2018-08-21 | 江苏省中国科学院植物研究所 | A kind of mulberry fruit pomace composition of auxiliary hyperglycemic and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104825797A (en) * | 2015-05-04 | 2015-08-12 | 威海御膳坊生物科技有限公司 | Propolis-bitter gourd composite preparation |
| CN105341928A (en) * | 2015-12-02 | 2016-02-24 | 烟台燕园科玛健康产业有限公司 | Health-care food capable of reducing blood sugar |
| CN105831318A (en) * | 2016-04-14 | 2016-08-10 | 朱从恩 | Polypeptide tea for blood glucose reduction and manufacturing method of polypeptide tea |
-
2016
- 2016-08-25 CN CN201610723929.6A patent/CN106236855A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104825797A (en) * | 2015-05-04 | 2015-08-12 | 威海御膳坊生物科技有限公司 | Propolis-bitter gourd composite preparation |
| CN105341928A (en) * | 2015-12-02 | 2016-02-24 | 烟台燕园科玛健康产业有限公司 | Health-care food capable of reducing blood sugar |
| CN105831318A (en) * | 2016-04-14 | 2016-08-10 | 朱从恩 | Polypeptide tea for blood glucose reduction and manufacturing method of polypeptide tea |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108420063A (en) * | 2018-03-20 | 2018-08-21 | 江苏省中国科学院植物研究所 | A kind of mulberry fruit pomace composition of auxiliary hyperglycemic and preparation method thereof |
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Application publication date: 20161221 |