CN106215209A - A kind of the sterilization effect method of inspection, Apparatus and system - Google Patents
A kind of the sterilization effect method of inspection, Apparatus and system Download PDFInfo
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- CN106215209A CN106215209A CN201610608239.6A CN201610608239A CN106215209A CN 106215209 A CN106215209 A CN 106215209A CN 201610608239 A CN201610608239 A CN 201610608239A CN 106215209 A CN106215209 A CN 106215209A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/26—Accessories or devices or components used for biocidal treatment
- A61L2/28—Devices for testing the effectiveness or completeness of sterilisation, e.g. indicators which change colour
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/24—Medical instruments, e.g. endoscopes, catheters, sharps
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The embodiment of the invention discloses a kind of the sterilization effect method of inspection, Apparatus and system.The method includes: when inspection enabling signal being detected, send control instruction to excitation source, so that excitation source sends corresponding exciting light according to control instruction；Obtaining the light signal acquisition device signal of telecommunication according to the optical signal output collected, optical signal is that the biological indicator after sterilization treatment produces when the light that is excited irradiates；The magnitude of voltage of the signal of telecommunication is monitored in real time, and judges whether sterilizing success according to magnitude of voltage.The embodiment of the present invention by being converted into the signal of telecommunication by the optical signal that biological indicator produces, and monitors the magnitude of voltage of the signal of telecommunication, to judge sterilizing whether success, compared with prior art, has advantage short, easy and simple to handle Check-Out Time.
Description
Technical field
The present embodiments relate to Micro biological Tests device, be specifically related to a kind of the sterilization effect method of inspection, device and be
System.
Background technology
Sterilization determination typically refers to armarium, operating theater instruments needs all antibacterials to its surface during using
The monitoring of the result of sterilizing is carried out with other vivo.Traditional sterilization process includes high-temp steam sterilizing, epoxy second
Alkane sterilizing, hydrogen peroxide low-temperature plasma sterilization and radiation sterilization etc..
In order to verify the effect of sterilization process, it usually needs sterilizing result is detected.Biological indicator is by extensively at present
The general effectiveness being applied to check sterilization process, its basic operation is the biological indicator containing microbial spores and needs to be gone out
The medical apparatus and instruments of bacterium together carries out complete sterilizing program, and the taking-up carrying out sterilization process is placed into this spore afterwards applicable
In the suitable environment sprouted and grow, the survival rate of detection spore, generally, spore will be more than the microorganism of the overwhelming majority
It is difficult to kill, therefore, if spore is killed by this sterilization process, then it is believed that this sterilization process kills the half on apparatus
Microorganism, sterilization process achieves successfully.
The most traditional detection method and equipment are the survival conditions utilizing microscope to observe spore, refer to specifically: will
The spore of sterilized process carries out the cultivation of about 72 hours in specific temperature and culture fluid, then by culture fluid micro-
Microscopic observation, thus determine whether the survival of microorganism.
Develop the most again the detection method and equipment utilizing acid-base indicator bacterial indicator growth course pH value to change, tool
Refer to for body: biological indicator is by being loaded with the bacterium sheet of bacterial spore and including the ampoule bottle group of culture fluid of acid-base indicator
Become, after sterilizing terminates, squeeze broken ampoule bottle, make bacterium sheet be fully contacted with culture fluid.The most successful according to sterilizing, it may appear that following two
The situation of kind: if sterilizing failure, spore is the most dead, then have bacterial growth, bacterial growth with culture fluid after spore contacts
Time can excrete the material of acidity or alkalescence, these materials can change the ph value of culture fluid, makes soda acid contained in culture fluid refer to
Show thing variable color.If sterilizing success, bacterial spore is all dead, then do not have antibacterial with culture fluid after bacterial spore contacts raw
Long, the pH value of culture fluid itself will not change, and therefore the color of culture fluid will not change, and still keeps original color,
Sterilizing success is judged with this.
During realizing the embodiment of the present invention, inventor finds that above two conventional method exists mistake Check-Out Time
Problem long, that operation is complicated.
Summary of the invention
One purpose of the embodiment of the present invention is that the Check-Out Time that solution prior art exists is long, operates complicated asking
Topic.
The embodiment of the present invention proposes a kind of sterilization effect method of inspection, including:
When inspection enabling signal being detected, send control instruction to excitation source, so that described excitation source is according to institute
State control instruction and send corresponding exciting light；
Obtaining the light signal acquisition device signal of telecommunication according to the optical signal output collected, described optical signal is sterilization treatment
After biological indicator produce when by described excitation light irradiation；
The magnitude of voltage of the described signal of telecommunication is monitored in real time, and judges whether sterilizing success according to described magnitude of voltage.
Preferably, described judge whether that the successful step of sterilizing specifically includes according to described magnitude of voltage:
If monitoring is known when described magnitude of voltage is more than setting more than setting voltage threshold value and persistent period in Preset Time
Between threshold value, then judge sterilizing success；
If it is not, then sterilizing failure.
Preferably, the method also includes:
Obtain the adjusting thresholds instruction of outside input；
Described setting voltage threshold value or described setting time threshold is adjusted according to the instruction of described adjusting thresholds.
The invention allows for a kind of sterilization effect verifying attachment, including:
Instruction sending module, for when inspection enabling signal being detected, sending control instruction to excitation source, so that institute
State excitation source and send exciting light according to described control instruction；
Acquisition module, for obtaining the light signal acquisition device signal of telecommunication according to the optical signal output collected, described light
Signal is that the biological indicator after sterilization treatment produces when by described excitation light irradiation；
Monitoring processing module, for monitoring the magnitude of voltage of the described signal of telecommunication in real time, and sentences according to described magnitude of voltage
It is disconnected that whether sterilizing is successful.
The invention allows for a kind of sterilization effect checking system, including:
Spore culture tank, the biological indicator after cultivating sterilization treatment；
Light signal acquisition device, for gathering the optical signal that described biological indicator produces when the light that is excited irradiates, and
The optical signal collected is converted into the signal of telecommunication；
Primary processor, for when inspection enabling signal being detected, sending control instruction to excitation source, swashs so that described
Luminous source sends exciting light to described biological indicator；And the magnitude of voltage of the signal of telecommunication received is monitored in real time, with root
Sterilizing success is judged whether according to described magnitude of voltage.
Preferably, described light signal acquisition device includes: the first filter plate, the second filter plate, silicon photo diode and long-pending
Divide device；
Described first filter plate, between described excitation source and described spore culture tank, for described exciting light
The exciting light that source sends is filtered processing；
Described second filter plate, between described spore culture tank and described silicon photo diode, for described biology
The optical signal that indicator produces is filtered processing；
Described silicon photo diode, for the optical signal received is converted into the signal of telecommunication, and transmits the described signal of telecommunication extremely
Described integrator；
Described integrator, for being amplified process to the described signal of telecommunication.
Preferably, also include: first from processor；
Described first from processor, for the signal of telecommunication received is carried out analog-to-digital conversion process；Gather the training of described spore
Support the temperature of groove, and according to the temperature control heater collected, to adjust the temperature of described spore culture tank.
Preferably, also include: second from processor；
Described second from processor, connects described host scm, liquid crystal indicator and button respectively, is used for receiving described
The Monitoring Data that primary processor is sent by USART transmitter, and described Monitoring Data is transmitted to described liquid crystal indicator
Display；User is transmitted to described primary processor by described button inputted operational order by USART transmitter, so that institute
State primary processor and perform respective operations.
Preferably, also include: eeprom memory；
Described eeprom memory, is used for storing Monitoring Data, and described Monitoring Data is that described primary processor is connect by SPI
Mouth transmits to described eeprom memory.
Preferably, described primary processor, first be single-chip microcomputer from processor and second from processor.
As shown from the above technical solution, a kind of sterilization effect method of inspection of embodiment of the present invention proposition, Apparatus and system
By the optical signal that biological indicator produces being converted into the signal of telecommunication, and monitor the magnitude of voltage of the signal of telecommunication, whether to judge sterilizing
Success, compared with prior art, has advantage short, easy and simple to handle Check-Out Time.
Accompanying drawing explanation
By being more clearly understood from the features and advantages of the present invention with reference to accompanying drawing, accompanying drawing is schematic and should not manage
Solve as the present invention is carried out any restriction, in the accompanying drawings:
Fig. 1 shows the schematic flow sheet of the sterilization effect method of inspection that one embodiment of the invention proposes；
Fig. 2 shows the structural representation of the sterilization effect verifying attachment that one embodiment of the invention proposes；
Fig. 3 shows the structural representation of the sterilization effect checking system that one embodiment of the invention proposes.
Detailed description of the invention
For making the purpose of the embodiment of the present invention, technical scheme and advantage clearer, below in conjunction with the embodiment of the present invention
In accompanying drawing, the technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is
A part of embodiment of the present invention rather than whole embodiments.Based on the embodiment in the present invention, ordinary skill people
The every other embodiment that member is obtained on the premise of not making creative work, broadly falls into the scope of protection of the invention.
Fig. 1 shows the schematic flow sheet of the sterilization effect method of inspection that one embodiment of the invention proposes, and sees Fig. 1, should
The sterilization effect method of inspection, including:
110, detect inspection enabling signal time, processor sends control instruction to excitation source so that described in excite
Light source sends corresponding exciting light according to described control instruction；
It should be noted that processor is when receiving the detection enabling signal of outside input, generate corresponding control instruction,
And control instruction is sent to LASER Light Source, send corresponding exciting light according to control instruction triggering LASER Light Source；
It will be appreciated that after sterilization treatment completes, biological indicator is put in spore culture tank by user；Inspection herein
Test enabling signal and be user's signal starting inspection by the input of the device such as button, switch；
Wherein, corresponding exciting light is and the exciting light of antibacterial relevant wavelength to be detected.
120, obtaining the light signal acquisition device signal of telecommunication according to the optical signal output collected, described optical signal is sterilizing
Biological indicator after process produces when by described excitation light irradiation；
It should be noted that excitation source is after biological indicator sends exciting light, biological indicator will be excited and
Producing fluorescence, the form with optical signal gathers by fluorescence by light signal acquisition device, and light signal acquisition device will collect
Optical signal is converted into the signal of telecommunication, and transmits the signal of telecommunication to processor；
130, the magnitude of voltage of the described signal of telecommunication is monitored in real time, and judge whether that sterilizing becomes according to described magnitude of voltage
Merit.
It should be noted that the magnitude of voltage of its various location can be obtained according to the waveform of the signal of telecommunication, by voltage
Value is monitored, to judge whether magnitude of voltage meets the requirement of sterilizing.
Visible, the present embodiment is by being converted into the signal of telecommunication by the optical signal that biological indicator produces, and monitors the signal of telecommunication
Magnitude of voltage, to judge sterilizing whether success, compared with prior art, has advantage short, easy and simple to handle Check-Out Time.
In the present embodiment, step 130 specifically includes:
If monitoring is known when described magnitude of voltage is more than setting more than setting voltage threshold value and persistent period in Preset Time
Between threshold value, then judge sterilizing success；
If it is not, then sterilizing failure.
It should be noted that the present embodiment with detect inspection enabling signal as time started, with the length of Preset Time
For scope, magnitude of voltage being monitored, if not monitoring magnitude of voltage in Preset Time to be more than setting voltage threshold value, then judging
Sterilizing failure；
If monitoring the signal of telecommunication that there is magnitude of voltage more than setting voltage threshold value in Preset Time, then monitoring is held further
The continuous time, whether if otherwise judging, sterilizing was failed more than setting time threshold；The most then judge sterilizing success.
Wherein, Preset Time, setting voltage threshold value and setting time threshold are the most adjustable.
In order to improve the suitability of this programme, this programme also includes:
Obtain the adjusting thresholds instruction of outside input；
Described setting voltage threshold value or described setting time threshold is adjusted according to the instruction of described adjusting thresholds.
It should be noted that for different antibacterials, its characteristic is different, it is necessary to set threshold value be likely to difference；
Therefore, the present embodiment sets a threshold to adjustable, particularly as follows: user can write adjustment by external equipment in processor
Order, so that processor performs to adjust order, and then adjusts threshold size.
For method embodiment, in order to be briefly described, therefore it is all expressed as a series of combination of actions, but ability
Field technique personnel should know, embodiment of the present invention is not limited by described sequence of movement, because according to the present invention
Embodiment, some step can use other orders or carry out simultaneously.Secondly, those skilled in the art also should know,
Embodiment described in this description belongs to preferred implementation, involved action embodiment party the most of the present invention
Necessary to formula.
Fig. 2 shows the structural representation of the sterilization effect verifying attachment that one embodiment of the invention proposes, and sees Fig. 2, should
Sterilization effect verifying attachment, including: instruction sending module 21, acquisition module 22 and monitoring processing module 23；Wherein,
Instruction sending module 21, for when inspection enabling signal being detected, sending control instruction to excitation source, so that
Described excitation source sends exciting light according to described control instruction；
Acquisition module 22, for obtaining the light signal acquisition device signal of telecommunication according to the optical signal output collected, described
Optical signal is that the biological indicator after sterilization treatment produces when by described excitation light irradiation；
Monitoring processing module 23, for monitoring in real time the magnitude of voltage of the described signal of telecommunication, and according to described magnitude of voltage
Judge whether sterilizing success.
It should be noted that instruction sending module 21 is detecting when inspection enabling signal being detected, to excitation source
Send control instruction, so that described excitation source sends exciting light according to described control instruction；Now, light signal acquisition device is adopted
The optical signal that biological indicator after collection sterilization treatment produces when by described excitation light irradiation, and convert optical signal into telecommunications
Number transmission to acquisition module 22；Acquisition module 22 is by signal of telecommunication transmission to monitoring processing module 23, and monitoring processing module 23 is to electricity
The magnitude of voltage of signal is monitored in real time, if monitoring knows that described magnitude of voltage more than setting voltage threshold value and is held in Preset Time
The continuous time more than setting time threshold, then judges sterilizing success.
In order to improve the suitability of this programme, this device also includes: instruction adjusting module；
Instruction adjusting module, for obtaining the adjusting thresholds instruction of outside input, and adjusts according to the instruction of described adjusting thresholds
Whole described setting voltage threshold value or described setting time threshold.
For device embodiments, due to itself and method embodiment basic simlarity, so describe is fairly simple,
Relevant part sees the part of method embodiment and illustrates.
It should be noted that, in all parts of assembly of the invention, the function to be realized according to it and to therein
Parts have carried out logical partitioning, but, the present invention is not only restricted to this, can as required all parts be repartitioned or
Person combines.
Fig. 3 shows the structural representation of the sterilization effect checking system that one embodiment of the invention proposes, and sees Fig. 3, should
Sterilization effect checking system, including: spore culture tank 31, light signal acquisition device 32 and primary processor 33；Wherein,
Spore culture tank 31, the biological indicator after cultivating sterilization treatment；
Light signal acquisition device 32, for gathering the optical signal that described biological indicator produces when the light that is excited irradiates,
And the optical signal collected is converted into the signal of telecommunication；
Primary processor 33, for when inspection enabling signal being detected, sending control instruction to excitation source, so that described
Excitation source sends exciting light to described biological indicator；And the magnitude of voltage of the signal of telecommunication received is monitored in real time, with
Sterilizing success is judged whether according to described magnitude of voltage.
It should be noted that the biological indicator through sterilization treatment is inserted in spore culture tank 31, in certain temperature
Cultivating under degree, the bacterial spore do not killed is germination and growth in the culture fluid that biological indicator includes, growth and breeding process
Can produce a kind of organized enzyme and produce fluorescent material with the substance reaction in culture fluid, the excitation light irradiation that excitation source sends is to glimmering
Can excite generation fluorescence during stimulative substance, this fluorescence is gathered by light signal acquisition device 32, and is transferred to after being converted into the signal of telecommunication main
Processor 33, the signal collected is processed, monitors by primary processor 33, when monitoring signal value continuously more than the threshold set
During value, it is determined that for sterilizing failure, be otherwise judged to sterilizing success；Wherein, primary processor 33 is preferably single-chip microcomputer.
In the present embodiment, light signal acquisition device 32 includes: the first filter plate, the second filter plate, silicon photo diode and
Integrator；
Described first filter plate, between described excitation source and described spore culture tank, for described exciting light
The exciting light that source sends is filtered processing；
Described second filter plate, between described spore culture tank and described silicon photo diode, for described biology
The optical signal that indicator produces is filtered processing；
Described silicon photo diode, for the optical signal received is converted into the signal of telecommunication, and transmits the described signal of telecommunication extremely
Described integrator；
Described integrator, for being amplified process to the described signal of telecommunication.
It should be noted that light signal acquisition device 32 carries out filtration treatment by the second optical filter to collecting optical signal
After, by silicon photo diode, optical signal changing into the faint signal of telecommunication, the signal of telecommunication is changed after integrator amplifies again afterwards
Become the output voltage of 0～5 volt, and be sent to host scm by iic bus, at the host scm signal to collecting
Reason, monitoring.
In another possible embodiments, this device also includes: first from processor；
Described first from processor, for the signal of telecommunication received is carried out analog-to-digital conversion process；Gather the training of described spore
Support the temperature of groove, and according to the temperature control heater collected, to adjust the temperature of described spore culture tank；Wherein, first
Being preferably single-chip microcomputer from processor, first be in Fig. 3 is from single-chip microcomputer.
See Fig. 3 understand, after integrator is to signal of telecommunication processing and amplifying, first from single-chip microcomputer by this output signal of telecommunication via
ADC is sent to host scm by iic bus after processing；
And, first from single-chip microcomputer also have control culture tank temperature effect, it is as follows that it realizes process: obtain temperature pass
The temperature information of the culture tank of sensor Real-time Collection, contrasts current temperature and preset temperature, to generate control instruction, will control
Instruction sends to temperature sense control system, so that temperature sense control system performs heating action；
Temperature sense control system is formed from processor, thermocouple and heating tape by the 3rd, and its temperature range controls 45
～between 70 degree.
In another possible embodiments, this device also includes: second from processor；
Described second from processor, connects described host scm, liquid crystal indicator and button respectively, is used for receiving described
The Monitoring Data that primary processor is sent by USART transmitter, and described Monitoring Data is transmitted to described liquid crystal indicator
Display；User is transmitted to described primary processor by described button inputted operational order by USART transmitter, so that institute
Stating primary processor and perform respective operations, wherein, the second processor is preferably single-chip microcomputer, and second be in Fig. 3 is from single-chip microcomputer.
In another possible embodiments, this device also includes: eeprom memory；
Described eeprom memory, is used for storing Monitoring Data, and described Monitoring Data is that described primary processor is connect by SPI
Mouth transmits to described eeprom memory.
It should be noted that the present embodiment is by the existing information of eeprom memory erasing, reprogramming, to improve system
Operability.
The work process of native system is described with example below:
Commercially available biological indicator is put in steriliser together with apparatus subject to sterilization and carries out sterilization process, wherein will be raw
Thing indicator is positioned over the most weak region of sterilization effect in steriliser (region particular location can seek advice from steriliser manufacturer).Sterilizing
After process terminates, the biological indicator carrying out sterilization process being positioned in the culture tank of the present invention, arranging culture tank temperature is
56 degrees Celsius, being racked by the ampoule bottle of biological indicator, the culture fluid of ampoule interior contacts with spore, the spore not being killed
Carrying out microorganism culturing under culture fluid environment and under design temperature, spore is sprouted and incubation can produce special enzyme, enzyme
React with the indicant added in culture fluid and produce the material that can produce fluorescence；Start microorganism culturing and start ultraviolet light simultaneously
Source (excitation source), light source irradiates biological indicator through the first optical filter, and the starting stage that microorganism is sprouted, almost without fluorescence
Material, therefore, silicon photo diode does not receives fluorescence signal, and along with growth of microorganism, the amount of the organized enzyme of generation increases, and enzyme will
Indicant in culture fluid decomposes the substantial amounts of fluorescent material of generation to be increased, and the optical signal that silicon photo diode receives strengthens, and light is believed
Number via integrator amplify output one voltage signal, voltage signal is received by single-chip microcomputer and processes, when voltage signal is the biggest
When setting value, the present invention exports a positive signal instruction sterilizing failure, within 1 hour, is still not detected by voltage signal and surpasses
Go out setting value, be then judged to sterilizing success.
Visible, that this programme can the be sensitiveer bacterial growth found during sterilizing failure in biological indicator, detection finds
The time of bacterium colony is shorter, can complete in 1 hour detection, very convenient fast.
The all parts embodiment of the present invention can realize with hardware, or to transport on one or more processor
The software module of row realizes, or realizes with combinations thereof.In this device, PC is by realizing the Internet to equipment or device
Remotely control, control equipment or the step of each operation of device accurately.The present invention is also implemented as performing here
Part or all equipment of described method or device program (such as, computer program and computer program product
Product).It is achieved in that the program of the present invention can store on a computer-readable medium, and the file or document tool that program produces
Have and statistically can produce data report and cpk report etc., power amplifier can be carried out batch testing and add up.It should be noted
The present invention will be described rather than limits the invention to state embodiment, and those skilled in the art are without departing from institute
Replacement embodiment can be designed in the case of the scope of attached claim.In the claims, should not will be located between bracket
Any reference marks be configured to limitations on claims.Word " comprises " and does not excludes the presence of the unit not arranged in the claims
Part or step.Word "a" or "an" before being positioned at element does not excludes the presence of multiple such element.The present invention can borrow
Help include the hardware of some different elements and realize by means of properly programmed computer.If listing equipment for drying
Unit claim in, several in these devices can be specifically to be embodied by same hardware branch.Word first,
Second and third use do not indicate that any order.Can be title by these word explanations.
Although being described in conjunction with the accompanying embodiments of the present invention, but those skilled in the art can be without departing from this
Making various modifications and variations in the case of bright spirit and scope, such amendment and modification each fall within by claims
Within limited range.
Claims (10)
1. a sterilization effect method of inspection, it is characterised in that including:
When inspection enabling signal being detected, send control instruction to excitation source, so that described excitation source is according to described control
Instruction processed sends corresponding exciting light；
Obtain the light signal acquisition device signal of telecommunication according to the optical signal output collected, after described optical signal is sterilization treatment
Biological indicator produces when by described excitation light irradiation；
The magnitude of voltage of the described signal of telecommunication is monitored in real time, and judges whether sterilizing success according to described magnitude of voltage.
Method the most according to claim 1, it is characterised in that described judge whether that sterilizing is successful according to described magnitude of voltage
Step specifically includes:
If monitoring knows that described magnitude of voltage is more than setting time threshold more than setting voltage threshold value and persistent period in Preset Time
Value, then judge sterilizing success；
If it is not, then sterilizing failure.
Method the most according to claim 2, it is characterised in that the method also includes:
Obtain the adjusting thresholds instruction of outside input；
Described setting voltage threshold value or described setting time threshold is adjusted according to the instruction of described adjusting thresholds.
4. a sterilization effect verifying attachment, it is characterised in that including:
Instruction sending module, for when inspection enabling signal being detected, sending control instruction to excitation source, swashs so that described
Luminous source sends exciting light according to described control instruction；
Acquisition module, for obtaining the light signal acquisition device signal of telecommunication according to the optical signal output collected, described optical signal
Produce when by described excitation light irradiation for the biological indicator after sterilization treatment；
Monitoring processing module, for the magnitude of voltage of the described signal of telecommunication is monitored in real time, and according to the judgement of described magnitude of voltage be
No sterilizing success.
5. a sterilization effect checking system, it is characterised in that including:
Spore culture tank, the biological indicator after cultivating sterilization treatment；
Light signal acquisition device, for gathering the optical signal that described biological indicator produces when the light that is excited irradiates, and will adopt
Collect to optical signal be converted into the signal of telecommunication；
Primary processor, for when inspection enabling signal being detected, sending control instruction to excitation source, so that described exciting light
Source sends exciting light to described biological indicator；And the magnitude of voltage of the signal of telecommunication received is monitored in real time, with according to institute
State magnitude of voltage and judge whether sterilizing success.
System the most according to claim 5, it is characterised in that described light signal acquisition device includes: the first filter plate,
Two filter plates, silicon photo diode and integrator；
Described first filter plate, between described excitation source and described spore culture tank, for sending out described excitation source
The exciting light gone out is filtered processing；
Described second filter plate, between described spore culture tank and described silicon photo diode, for described microbial administration
The optical signal that agent produces is filtered processing；
Described silicon photo diode, for being converted into the signal of telecommunication, and by the transmission of the described signal of telecommunication to described by the optical signal received
Integrator；
Described integrator, for being amplified process to the described signal of telecommunication.
System the most according to claim 5, it is characterised in that also include: first from processor；
Described first from processor, for the signal of telecommunication received is carried out analog-to-digital conversion process；Gather described spore culture tank
Temperature, and according to the temperature control heater collected, to adjust the temperature of described spore culture tank.
System the most according to claim 5, it is characterised in that also include: second from processor；
Described second from processor, connects described host scm, liquid crystal indicator and button respectively, is used for receiving described main place
The reason Monitoring Data that sent by USART transmitter of device, and described Monitoring Data is transmitted to described liquid crystal indicator shows；
User is transmitted to described primary processor by described button inputted operational order by USART transmitter, so that described master
Processor performs respective operations.
System the most according to claim 5, it is characterised in that also include: eeprom memory；
Described eeprom memory, is used for storing Monitoring Data, described Monitoring Data be described primary processor by SPI interface to
The transmission of described eeprom memory.
10. according to the system described in any one of claim 5-9, it is characterised in that described primary processor, first from processor and
Second is single-chip microcomputer from processor.
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| CN109395134A (en) * | 2018-11-29 | 2019-03-01 | 楚天科技股份有限公司 | A kind of hydrogen peroxide sterilization verification method |
| CN110887824A (en) * | 2019-12-02 | 2020-03-17 | 北京永安多谱检测科技有限公司 | Integrated modular peroxide detection device and detection method thereof |
| US11565015B2 (en) | 2016-09-15 | 2023-01-31 | Asp Global Manufacturing Gmbh | Biological indicator with variable resistance |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0212455A2 (en) * | 1985-08-07 | 1987-03-04 | Tosoh Corporation | Fluorescence detection apparatus for immunoassay |
| US6025189A (en) * | 1997-05-14 | 2000-02-15 | 3M Innovative Properties Company | Apparatus for reading a plurality of biological indicators |
| CN101231244A (en) * | 2008-02-15 | 2008-07-30 | 中国科学院上海微***与信息技术研究所 | Fluorescence detection micro-current control biochemical analyzer evoked by high-power LED |
| CN202216907U (en) * | 2011-06-09 | 2012-05-09 | 北京工业大学 | Fluorescence micro-spectrum detection device of biological chip |
| CN102854174A (en) * | 2011-07-25 | 2013-01-02 | 中国科学院烟台海岸带研究所 | Fluorescent dissolved oxygen online measure device, and dissolved oxygen detection method using it |
| CN103178848A (en) * | 2013-02-05 | 2013-06-26 | 中国科学院苏州生物医学工程技术研究所 | Photomultiplier tube signal controllable integral circuit |
| CN104237180A (en) * | 2013-06-18 | 2014-12-24 | 北京白象新技术有限公司 | Biological reader capable of rapidly verifying sterilizing effect |
-
2016
- 2016-07-28 CN CN201610608239.6A patent/CN106215209A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0212455A2 (en) * | 1985-08-07 | 1987-03-04 | Tosoh Corporation | Fluorescence detection apparatus for immunoassay |
| US6025189A (en) * | 1997-05-14 | 2000-02-15 | 3M Innovative Properties Company | Apparatus for reading a plurality of biological indicators |
| CN101231244A (en) * | 2008-02-15 | 2008-07-30 | 中国科学院上海微***与信息技术研究所 | Fluorescence detection micro-current control biochemical analyzer evoked by high-power LED |
| CN202216907U (en) * | 2011-06-09 | 2012-05-09 | 北京工业大学 | Fluorescence micro-spectrum detection device of biological chip |
| CN102854174A (en) * | 2011-07-25 | 2013-01-02 | 中国科学院烟台海岸带研究所 | Fluorescent dissolved oxygen online measure device, and dissolved oxygen detection method using it |
| CN103178848A (en) * | 2013-02-05 | 2013-06-26 | 中国科学院苏州生物医学工程技术研究所 | Photomultiplier tube signal controllable integral circuit |
| CN104237180A (en) * | 2013-06-18 | 2014-12-24 | 北京白象新技术有限公司 | Biological reader capable of rapidly verifying sterilizing effect |
Non-Patent Citations (2)
| Title |
|---|
| 柳淳编著: "《电子元器件与电路检测快速入门》", 30 April 2013, 北京：中国电力出版 * |
| 陈汝洪著: "《北京电影学院中国电影美术教育教学丛书后浪电影学院 影像构成基础》", 30 April 2016, 北京联合出版公司 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11565015B2 (en) | 2016-09-15 | 2023-01-31 | Asp Global Manufacturing Gmbh | Biological indicator with variable resistance |
| CN106822928A (en) * | 2017-02-27 | 2017-06-13 | 秦艳玲 | A kind of general surgery disinfection nursing device |
| CN109395134A (en) * | 2018-11-29 | 2019-03-01 | 楚天科技股份有限公司 | A kind of hydrogen peroxide sterilization verification method |
| CN110887824A (en) * | 2019-12-02 | 2020-03-17 | 北京永安多谱检测科技有限公司 | Integrated modular peroxide detection device and detection method thereof |
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