CN106166118A - A kind of Anti-hair loss, germinal preparation - Google Patents
A kind of Anti-hair loss, germinal preparation Download PDFInfo
- Publication number
- CN106166118A CN106166118A CN201610602602.3A CN201610602602A CN106166118A CN 106166118 A CN106166118 A CN 106166118A CN 201610602602 A CN201610602602 A CN 201610602602A CN 106166118 A CN106166118 A CN 106166118A
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- Prior art keywords
- hair
- preparation
- hair loss
- present
- germinal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to hair nursing recuperate field, be particularly a kind of Anti-hair loss, germinal preparation.According to mass percent, said preparation includes the dihydrosphingosine of 0.05～5%.The present invention is by test, within 8 weeks by final trophophase, hair can be transformed into the primary growth phase, by balance, microbiologic population improves scalp health, promotes scalp regeneration capacity, by suppressing 5 alpha-reductase balancing head generation long periods, anti-alopecia-stopping anagen of by being maintained by hair.
Description
Technical field
The present invention relates to hair nursing recuperate field, be particularly a kind of Anti-hair loss, germinal preparation.
Background technology
Hair, as one of the primary impression of people, is social signal, is related to self-respect and health degree, however as life
The increase of pressure and the quickening of rhythm of life, a lot of people occur in that the phenomenon of geromorphism, it is simply that hair all falls light light, draws
The reason playing alopecia is the most a variety of, such as Nervous and Mental Factors causes, body illness causes, use inferior shampoo, hair dye
Cause etc..
For anti-alopecia-stopping and the regrowth of promotion hair, in addition to the living habit kept fit and diet, more
If many people pay close attention to reaches the protection to hair by hair washing product or product for improving hair-growing, improve hair quality and promote the regeneration of hair
Long.
Mostly existing product for improving hair-growing, the especially product for improving hair-growing to male, be by oral or the androgen of external, but
Effect is the most notable.
Summary of the invention
The technical problem to be solved is to provide a kind of Anti-hair loss, germinal preparation, by balance natural on-off cycles of hair growth
In the cycle, strengthen hair follicle and improve scalp health, solving alopecia problem.
The present invention is achieved in that
A kind of Anti-hair loss, germinal preparation, according to mass percent, said preparation includes the dihydrosphingosine of 0.05～5%.
Further, said preparation includes the dihydrosphingosine of 0.1～2% to the present invention.
Further, said preparation includes the dihydrosphingosine of 0.1～0.5% to the present invention.
Further, according to mass percent, said preparation also includes the present invention:
Solubilizing agent: 2～3%；
Hydrophilic emollients: 2～3%；
Emollient: 0.5～1%；
Essence: 0.1～0.2%；
Ethanol: 40～50%；
Surplus is water.
Further, described solubilizing agent is selected from Cremophor RH40 to the present invention.
Further, described hydrophilic emollients is selected from PEG-7 glyceryl cocoate to the present invention.
Further, described emollient is selected from diethyl hexylcarbonate to the present invention.
The present invention compared with prior art, has the beneficial effects that: the present invention by 96 male of test (each formula 20～
28 people), age 30～60 years old, there is dispersibility, alopecia that non-health is relevant and thin and lifeless hair, use 0.1%,
0.2%, the preparation of the dihydrosphingosine content of 0.5%, and control sample, is used for hair twice, totally 16 weeks, makes respectively every day
With front, after using after 8 weeks and 16 weeks, using digitized photography and expert estimation, conclusion is as follows: the present invention passes through test,
Within 8 weeks by final trophophase, hair can be transformed into the primary growth phase, by balance, microbiologic population improves scalp health, carries
Rise scalp regeneration capacity, by suppression 5-5 alpha-reductases balancing head generation long period, by being maintained at the beginning of hair growth by hair
Phase anti-alopecia-stopping.
By marking hair quality and hair healthy, hair intensity, an amount and hair gloss are had aobvious by the present invention
Write and improve, scalp scurf is reduced and dry scalp degree has improvement, thus finally reduce alopecia.
Accompanying drawing explanation
Fig. 1 is that the present invention uses previous tester to tonsure the upgrowth situation of three days hairs；
Fig. 2 is that after the present invention uses 16 weeks, same tester tonsures the upgrowth situation of three days hairs；
Fig. 3 is the improvement scoring comparison diagram to hair quality that the embodiment of the present invention provides；
Fig. 4 is the improvement scoring comparison diagram to hair healthy that the embodiment of the present invention provides.
Detailed description of the invention
In order to make the purpose of the present invention, technical scheme and advantage clearer, below in conjunction with embodiment, to the present invention
It is further elaborated.Should be appreciated that specific embodiment described herein, only in order to explain the present invention, is not used to
Limit the present invention.
A kind of Anti-hair loss, germinal preparation, according to mass percent, said preparation includes the dihydrosphingosine of 0.01～5%,
Embodiment 1
According to mass percent, said preparation includes the dihydrosphingosine of 0.1%, solubilizing agent: 3%；Hydrophilic emollients: 2%；
Emollient: 0.5%；Essence: 0.2%；Ethanol: 50%；Surplus is water.Wherein solubilizing agent is selected from Cremophor RH40, parent
Water emollient is selected from PEG-7 glyceryl cocoate.Emollient is selected from diethyl hexylcarbonate.
The molecular formula of dihydrosphingosine is: C18H39NO2, the numbered 764-22-7 of CAS.
Embodiment 2
According to mass percent, said preparation includes the dihydrosphingosine of 0.2%, solubilizing agent: 3%；Hydrophilic emollients: 2%；
Emollient: 0.5%；Essence: 0.2%；Ethanol: 50%；Surplus is water.Wherein solubilizing agent is selected from Cremophor RH40, parent
Water emollient is selected from PEG-7 glyceryl cocoate.Emollient is selected from diethyl hexylcarbonate.
Embodiment 3
According to mass percent, said preparation includes the dihydrosphingosine of 0.5%, solubilizing agent: 3%；Hydrophilic emollients: 2%；
Emollient: 0.5%；Essence: 0.2%；Ethanol: 50%；Surplus is water.Wherein solubilizing agent is selected from Cremophor RH40, parent
Water emollient is selected from PEG-7 glyceryl cocoate.Emollient is selected from diethyl hexylcarbonate.
Preparation process is:
Solubilizing agent and dihydrosphingosine are mixed and heated to about 60～150 degrees Celsius, until forming uniform solution, step by step
Add hydrophilic emollients, emollient and ethanol with this to stir, be eventually adding water dilution.
The preparation prepared by embodiment 1～3 is used to be used for testing:
Test method:
Test 96 male (each formula 20～28 people), age 30～60 years old, there is dispersibility, relevant the taking off of non-health
Send out and thin and lifeless hair, use the preparation of the dihydrosphingosine content of 0.1%, 0.2%, 0.5%, and comparison
Sample, every day for twice of hair, totally 16 weeks, the most before use, after using after 8 weeks and 16 weeks, use digitized photography with
And expert estimation.
Conclusion:
See Fig. 1～Fig. 2, Fig. 1 be use before tonsure three days after the upgrowth situation of hair, Fig. 2 is for tonsuring after using 16 weeks
The upgrowth situation of hair after three days, but when 8 weeks, the hair ratio anagen of being in had occurred and that change.Show,
After application, early growth period number of hairs rises, and shows that hair follicle is had stimulation.Fig. 3 Yu Fig. 4 is expert analysis mode, Fig. 3
That hair quality improves degree, be respectively the dihydrosphingosine content of 0.1%, 0.2%, 0.5% preparation and with the commenting of matched group
Dividing result, it is seen that in the embodiment of the present invention, after using the present invention, hair intensity, an amount and hair gloss all obtain the biggest
Improve；Fig. 4 is that the scalp health that the embodiment of the present invention provides improves degree, it can be seen that after using the present invention, overall scalp
Health degree, scalp scurf ratio and dry scalp degree all improve substantially.
Hair, by test, can be transformed into the primary growth phase by final trophophase by the present invention within 8 weeks, micro-by balance
Biome improves scalp health, promotes scalp regeneration capacity, by suppression 5-5 alpha-reductases balancing head generation long period, passes through
Anti-alopecia-stopping anagen that hair being maintained.
By marking hair quality and hair healthy, hair intensity, an amount and hair gloss are had aobvious by the present invention
Write and improve, scalp scurf is reduced and dry scalp degree has improvement, thus finally reduce alopecia.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all essences in the present invention
Any amendment, equivalent and the improvement etc. made within god and principle, should be included within the scope of the present invention.
Claims (7)
1. an Anti-hair loss, germinal preparation, it is characterised in that according to mass percent, said preparation includes the dihydro of 0.05～5%
Sphingol.
2. according to the Anti-hair loss described in claim 1, germinal preparation, it is characterised in that said preparation includes the dihydro of 0.1～2%
Sphingol.
3. according to the Anti-hair loss described in claim 1, germinal preparation, it is characterised in that said preparation includes the two of 0.1～0.5%
Hydrogen sphingol.
4. according to the Anti-hair loss described in claim 1, germinal preparation, it is characterised in that according to mass percent, said preparation also wraps
Include:
Solubilizing agent: 2～3%；
Hydrophilic emollients: 2～3%；
Emollient: 0.5～1%；
Essence: 0.1～0.2%；
Ethanol: 40～50%；
Surplus is water.
5. according to the Anti-hair loss described in claim 4, germinal preparation, it is characterised in that described solubilizing agent hydrogenates selected from PEG-40
Oleum Ricini.
6. according to the Anti-hair loss described in claim 4, germinal preparation, it is characterised in that described hydrophilic emollients is sweet selected from PEG-7
Oil palm oleate.
7. according to the Anti-hair loss described in claim 4, germinal preparation, it is characterised in that described emollient is selected from carbonic acid diethyl
Own ester.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610602602.3A CN106166118A (en) | 2016-07-28 | 2016-07-28 | A kind of Anti-hair loss, germinal preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610602602.3A CN106166118A (en) | 2016-07-28 | 2016-07-28 | A kind of Anti-hair loss, germinal preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106166118A true CN106166118A (en) | 2016-11-30 |
Family
ID=58066284
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610602602.3A Pending CN106166118A (en) | 2016-07-28 | 2016-07-28 | A kind of Anti-hair loss, germinal preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106166118A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108066221A (en) * | 2018-01-16 | 2018-05-25 | 广州市聚吉科绿色化学共性技术研究院有限公司 | A kind of composition for preventing alopecia |
| CN109793681A (en) * | 2018-12-26 | 2019-05-24 | 拉芳家化股份有限公司 | It is a kind of containing educating the shampoo composite for sending out hair loss composite reactive Essence anti- |
| CN110314105A (en) * | 2019-06-20 | 2019-10-11 | 上海绿瑞生物科技有限公司 | A kind of hair-loss preventing and hair-restoring class Essence and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103764108A (en) * | 2011-08-03 | 2014-04-30 | 赢创德固赛有限公司 | Use of sphinganine to improve the visual appearance of skin and hair |
| WO2015118281A1 (en) * | 2014-02-10 | 2015-08-13 | Dermaconcept Jmc | Composition for controlling hair loss |
| CN105555254A (en) * | 2013-09-12 | 2016-05-04 | 莱雅公司 | Process for treating keratin fibres with an oxidised polysaccharide and a sphingosine compound |
| CN105579020A (en) * | 2013-07-29 | 2016-05-11 | 赢创德固赛有限公司 | Formulations containing sphinganine |
-
2016
- 2016-07-28 CN CN201610602602.3A patent/CN106166118A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103764108A (en) * | 2011-08-03 | 2014-04-30 | 赢创德固赛有限公司 | Use of sphinganine to improve the visual appearance of skin and hair |
| CN105579020A (en) * | 2013-07-29 | 2016-05-11 | 赢创德固赛有限公司 | Formulations containing sphinganine |
| CN105555254A (en) * | 2013-09-12 | 2016-05-04 | 莱雅公司 | Process for treating keratin fibres with an oxidised polysaccharide and a sphingosine compound |
| WO2015118281A1 (en) * | 2014-02-10 | 2015-08-13 | Dermaconcept Jmc | Composition for controlling hair loss |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108066221A (en) * | 2018-01-16 | 2018-05-25 | 广州市聚吉科绿色化学共性技术研究院有限公司 | A kind of composition for preventing alopecia |
| CN109793681A (en) * | 2018-12-26 | 2019-05-24 | 拉芳家化股份有限公司 | It is a kind of containing educating the shampoo composite for sending out hair loss composite reactive Essence anti- |
| CN110314105A (en) * | 2019-06-20 | 2019-10-11 | 上海绿瑞生物科技有限公司 | A kind of hair-loss preventing and hair-restoring class Essence and preparation method thereof |
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20161130 |
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| WD01 | Invention patent application deemed withdrawn after publication |