CN106039423A - Silicification liquid for injector needle tip - Google Patents
Silicification liquid for injector needle tip Download PDFInfo
- Publication number
- CN106039423A CN106039423A CN201610383901.2A CN201610383901A CN106039423A CN 106039423 A CN106039423 A CN 106039423A CN 201610383901 A CN201610383901 A CN 201610383901A CN 106039423 A CN106039423 A CN 106039423A
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- China
- Prior art keywords
- silicone oil
- needle point
- syringe needle
- antioxidant
- liquid
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/10—Materials for lubricating medical devices
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention relates to the field of medical instrument coatings, and particularly discloses silicification liquid for an injector needle tip. The silicification liquid is applied to the surface of the injector needle tip and is obtained by mixing medical silicone oil with a silicone oil diluent according to the volume ratio of (3-8):1000. The medical silicone oil and the silicone oil diluent GF6000 are adopted, a proper formula is adopted, and lubrication of the injector needle tip is guaranteed while medical grade is realized. When the injector needle tip coated with the silicification liquid is used for injection, a patient does not feel any pricking caused by the needle tip piercing into skin tissue basically.
Description
Technical field
The present invention relates to medical device coatings field, a kind of silication liquid for syringe needle point.
Background technology
For intravenous syringe, being inserted directly into the internal of patient at needle point, the surface of needle point should be prone to slide
Thus avoid damage to tissue film and cause inflammation, and alleviation connects any misery that subject patient is stood, if needle point
It is left intact, it is easy to make needle point that the possibility that qualitative change is even got rusty occur during storing, have impact on the normal of pin
Use.
Therefore, provide lubricity for some medical apparatus and instruments, prior art is all by surface applied silicone oil, glycerol
Etc. providing, slide and the innovation of reducing friction resistance as improving.Can be by medical apparatus and instruments be immersed in containing silicone oil etc.
In solution, or being easily manufactured these medical apparatus and instruments by spraying silicone oil etc., therefore this technology is applicable to the doctor of wide scope
Treat apparatus.
Need arbitrarily it is obvious that can not fully meet on market as the coating of needle point only with silicone oil or glycerol
Ask.
Summary of the invention
The present invention is in order to overcome the deficiency of above-mentioned technical problem, it is provided that a kind of silication liquid for syringe needle point, can
To be fully solved above-mentioned technical problem.
The technical scheme solving above-mentioned technical problem is as follows:
A kind of silication liquid for syringe needle point, this silication liquid is coated on syringe needle point surface, by Medical silicone oil and
Silicon oil thinner is 3～8:1000 to mix according to volume ratio.
Say further, this silication liquid be 4～6:1000 mixing by Medical silicone oil and Silicon oil thinner according to volume ratio and
Become.
Furthermore, Medical silicone oil and Silicon oil thinner it is that 5:1000 mixes according to volume ratio.
Described Medical silicone oil is Sai Ao-102 Medical silicone oil.
Described Silicon oil thinner is GF-6000.
This silication liquid also includes thickening agent, antioxidant and antiwear additive, thickening agent, antioxidant and antiwear additive total amount and medical silicon
The mass ratio of oil is 0.1～0.3:1, and thickening agent, antioxidant and antiwear additive are 1:1:1 proportioning in mass ratio.
Described thickening agent is politef, and antioxidant is 2,6 ditertiary butyl p cresol, and antiwear additive is sulfuration isobutyl
Alkene and Semen Maydis mixed oil are the mixture of 2:1 proportioning in mass ratio.
The preparation method of this syringe needle point silication liquid, comprises the following steps:
(1) by Medical silicone oil and Silicon oil thinner addition reactor stir, add thickening agent and react, instead
Answering temperature is 120～130 DEG C, is cooled to less than 60 DEG C after reaction 0.5～1h；
(2) in the mixture that above-mentioned steps (1) has been reacted, add antioxidant and antiwear additive, stir 0.5h and get final product.
The present invention has selected Medical silicone oil and Silicon oil thinner GF6000, have found formula suitably, is meeting medical grade
Other lubrication that simultaneously ensure that syringe needle point.When the needle point of this silication liquid coated is used for injecting, patient almost feels not
The sensation of pricking that skin histology brings is inserted to needle point.The present invention is also added into antioxidant, antiwear additive and thickening agent so that this silication
Liquid can be the most oxidizable so that coating and durable in use, extreme-pressure anti-wear.Cost is relatively low, and has good high-temperature stability,
The needle point of syringe is served corrosion protection effect, there is the biggest market prospect.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is further detailed explanation.
Embodiment 1:
A kind of silication liquid for syringe needle point, this silication liquid is coated on syringe needle point surface, by Medical silicone oil and
Silicon oil thinner is that 3:1000 mixes according to volume ratio.
Medical silicone oil is Sai Ao-102 Medical silicone oil.
Silicon oil thinner is GF-6000.
The preparation method of this syringe needle point silication liquid is to add Medical silicone oil and Silicon oil thinner in reactor to stir
Uniformly.
Embodiment 2:
A kind of silication liquid for syringe needle point, this silication liquid is coated on syringe needle point surface, by Medical silicone oil and
Silicon oil thinner is that 8:1000 mixes according to volume ratio.
Medical silicone oil is Sai Ao-102 Medical silicone oil.
Silicon oil thinner is GF-6000.
Also include the quality of thickening agent, antioxidant and antiwear additive, thickening agent, antioxidant and antiwear additive total amount and Medical silicone oil
Ratio is 0.1:1, and thickening agent, antioxidant and antiwear additive are 1:1:1 proportioning in mass ratio.
Thickening agent is politef, and antioxidant is 2,6 ditertiary butyl p cresol, and antiwear additive is sulfide isobutene and jade
Rice mixed oil is the mixture of 2:1 proportioning in mass ratio.
The preparation method of this syringe needle point silication liquid, comprises the following steps:
(1) by Medical silicone oil and Silicon oil thinner addition reactor stir, add thickening agent and react, instead
Answering temperature is 120 DEG C, is cooled to less than 60 DEG C after reaction 1h；
(2) in the mixture that above-mentioned steps (1) has been reacted, add antioxidant and antiwear additive, stir 0.5h and get final product.
Embodiment 3:
A kind of silication liquid for syringe needle point, this silication liquid is coated on syringe needle point surface, by Medical silicone oil and
Silicon oil thinner is that 4:1000 mixes according to volume ratio.
Medical silicone oil is Sai Ao-102 Medical silicone oil.
Silicon oil thinner is GF-6000.
Also include the quality of thickening agent, antioxidant and antiwear additive, thickening agent, antioxidant and antiwear additive total amount and Medical silicone oil
Ratio is 0.3:1, and thickening agent, antioxidant and antiwear additive are 1:1:1 proportioning in mass ratio.
Thickening agent is politef, and antioxidant is 2,6 ditertiary butyl p cresol, and antiwear additive is sulfide isobutene and jade
Rice mixed oil is the mixture of 2:1 proportioning in mass ratio.
The preparation method of this syringe needle point silication liquid, comprises the following steps:
(1) by Medical silicone oil and Silicon oil thinner addition reactor stir, add thickening agent and react, instead
Answering temperature is 130 DEG C, is cooled to less than 60 DEG C after reaction 0.5h；
(2) in the mixture that above-mentioned steps (1) has been reacted, add antioxidant and antiwear additive, stir 0.5h and get final product.
Embodiment 4:
A kind of silication liquid for syringe needle point, this silication liquid is coated on syringe needle point surface, by Medical silicone oil and
Silicon oil thinner is that 6:1000 mixes according to volume ratio.
Medical silicone oil is Sai Ao-102 Medical silicone oil.
Silicon oil thinner is GF-6000.
Also include the quality of thickening agent, antioxidant and antiwear additive, thickening agent, antioxidant and antiwear additive total amount and Medical silicone oil
Ratio is 0.2:1, and thickening agent, antioxidant and antiwear additive are 1:1:1 proportioning in mass ratio.
Thickening agent is politef, and antioxidant is 2,6 ditertiary butyl p cresol, and antiwear additive is sulfide isobutene and jade
Rice mixed oil is the mixture of 2:1 proportioning in mass ratio.
The preparation method of this syringe needle point silication liquid, comprises the following steps:
(1) by Medical silicone oil and Silicon oil thinner addition reactor stir, add thickening agent and react, instead
Answering temperature is 125 DEG C, is cooled to less than 60 DEG C after reaction 45min；
(2) in the mixture that above-mentioned steps (1) has been reacted, add antioxidant and antiwear additive, stir 0.5h and get final product.
Embodiment 5:
A kind of silication liquid for syringe needle point, this silication liquid is coated on syringe needle point surface, by Medical silicone oil and
Silicon oil thinner is that 5:1000 mixes according to volume ratio.
Medical silicone oil is Sai Ao-102 Medical silicone oil.
Silicon oil thinner is GF-6000.
Also include thickening agent, antioxidant and antiwear additive, described thickening agent, antioxidant and antiwear additive total amount and Medical silicone oil
Mass ratio be 0.25:1, thickening agent, antioxidant and antiwear additive are 1:1:1 proportioning in mass ratio.
Thickening agent is politef, and antioxidant is 2,6 ditertiary butyl p cresol, and antiwear additive is sulfide isobutene and jade
Rice mixed oil is the mixture of 2:1 proportioning in mass ratio.
The preparation method of this syringe needle point silication liquid, comprises the following steps:
(1) by Medical silicone oil and Silicon oil thinner addition reactor stir, add thickening agent and react, instead
Answering temperature is 128 DEG C, is cooled to less than 60 DEG C after reaction 0.5h；
(2) in the mixture that above-mentioned steps (1) has been reacted, add antioxidant and antiwear additive, stir 0.5h and get final product.
The present invention has selected Medical silicone oil and Silicon oil thinner GF6000, have found formula suitably, is meeting medical grade
Other lubrication that simultaneously ensure that syringe needle point.When the needle point of this silication liquid coated is used for injecting, patient almost feels not
The sensation of pricking that skin histology brings is inserted to needle point.The present invention is also added into antioxidant, antiwear additive and thickening agent so that this silication
Liquid can be the most oxidizable so that coating and durable in use, extreme-pressure anti-wear.Cost is relatively low, and has good high-temperature stability,
The needle point of syringe is served corrosion protection effect, there is the biggest market prospect.
The above, be only presently preferred embodiments of the present invention, and the present invention not does any pro forma restriction, every depends on
According to any simple modification in the technical spirit of the present invention, above example made, equivalent variations, each fall within the guarantor of the present invention
Within the scope of protecting.
Claims (8)
1., for a silication liquid for syringe needle point, this silication liquid is coated on syringe needle point surface, it is characterised in that by curing
It is 3～8:1000 to mix with silicone oil and Silicon oil thinner according to volume ratio.
A kind of silication liquid for syringe needle point the most according to claim 1, it is characterised in that by Medical silicone oil and silicon
Oil diluent is 4～6:1000 to mix according to volume ratio.
A kind of silication liquid for syringe needle point the most according to claim 1, it is characterised in that by Medical silicone oil and silicon
Oil diluent is that 5:1000 mixes according to volume ratio.
A kind of silication liquid for syringe needle point the most according to claim 1, it is characterised in that described Medical silicone oil
For Sai Ao-102 Medical silicone oil.
A kind of silication liquid for syringe needle point the most according to claim 1, it is characterised in that described silicone oil dilution
Agent is GF-6000.
A kind of silication liquid for syringe needle point the most according to claim 1, it is characterised in that also include thickening agent,
Antioxidant and antiwear additive, described thickening agent, antioxidant and antiwear additive total amount is 0.1～0.3:1 with the mass ratio of Medical silicone oil,
Thickening agent, antioxidant and antiwear additive are 1:1:1 proportioning in mass ratio.
A kind of silication liquid for syringe needle point the most according to claim 6, it is characterised in that described thickening agent is
Politef, antioxidant is 2,6 ditertiary butyl p cresol, antiwear additive be sulfide isobutene and Semen Maydis mixed oil in mass ratio
Mixture for 2:1 proportioning.
8. the preparation method of a syringe needle point silication liquid as claimed in claim 6, it is characterised in that include following step
Rapid:
(1) by Medical silicone oil and Silicon oil thinner addition reactor stir, add thickening agent and react, reaction temperature
Degree is 120～130 DEG C, is cooled to less than 60 DEG C after reaction 0.5～1h；
(2) in the mixture that above-mentioned steps (1) has been reacted, add antioxidant and antiwear additive, stir 0.5h and get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610383901.2A CN106039423A (en) | 2016-06-02 | 2016-06-02 | Silicification liquid for injector needle tip |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610383901.2A CN106039423A (en) | 2016-06-02 | 2016-06-02 | Silicification liquid for injector needle tip |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106039423A true CN106039423A (en) | 2016-10-26 |
Family
ID=57173237
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610383901.2A Pending CN106039423A (en) | 2016-06-02 | 2016-06-02 | Silicification liquid for injector needle tip |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106039423A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108310473A (en) * | 2018-01-31 | 2018-07-24 | 采纳科技股份有限公司 | Injection needle silicone coating material and the injection needle for coating this coating |
| CN108853607A (en) * | 2018-09-28 | 2018-11-23 | 广州市爱创医疗科技有限公司 | A kind of insulin needle surface siliconization inorganic agent |
| CN111110928A (en) * | 2020-01-10 | 2020-05-08 | 常州市佳杰医疗器械有限公司 | Surface coating method for improving puncture degree of surgical knife |
| CN113429877A (en) * | 2021-06-28 | 2021-09-24 | 山东中保康医疗器具有限公司 | Silicone oil for silicification and silicification method of puncture needle |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1978566A (en) * | 2005-12-08 | 2007-06-13 | 上海康德莱企业发展集团有限公司 | Needle head siliconizing keagent, and its siliconizing method |
| CN102497894A (en) * | 2009-09-17 | 2012-06-13 | 贝克顿·迪金森公司 | Anti-infective lubricant for medical devices and methods for preparing the same |
| CN105542171A (en) * | 2016-02-02 | 2016-05-04 | 衢州市三诚化工有限公司 | Alcohol-soluble lubricant and preparation method thereof |
-
2016
- 2016-06-02 CN CN201610383901.2A patent/CN106039423A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1978566A (en) * | 2005-12-08 | 2007-06-13 | 上海康德莱企业发展集团有限公司 | Needle head siliconizing keagent, and its siliconizing method |
| CN102497894A (en) * | 2009-09-17 | 2012-06-13 | 贝克顿·迪金森公司 | Anti-infective lubricant for medical devices and methods for preparing the same |
| CN105542171A (en) * | 2016-02-02 | 2016-05-04 | 衢州市三诚化工有限公司 | Alcohol-soluble lubricant and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 沈萌红: "《机械设计 第1版第1次印刷》", 30 September 2012, 武汉：华中科技大学出版社 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108310473A (en) * | 2018-01-31 | 2018-07-24 | 采纳科技股份有限公司 | Injection needle silicone coating material and the injection needle for coating this coating |
| CN108853607A (en) * | 2018-09-28 | 2018-11-23 | 广州市爱创医疗科技有限公司 | A kind of insulin needle surface siliconization inorganic agent |
| CN111110928A (en) * | 2020-01-10 | 2020-05-08 | 常州市佳杰医疗器械有限公司 | Surface coating method for improving puncture degree of surgical knife |
| CN113429877A (en) * | 2021-06-28 | 2021-09-24 | 山东中保康医疗器具有限公司 | Silicone oil for silicification and silicification method of puncture needle |
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| PB01 | Publication | ||
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20161026 |
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| RJ01 | Rejection of invention patent application after publication |