CN1060349C - 调经祛斑胶囊及其制备方法 - Google Patents
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Abstract
调经祛斑胶囊及其制备方法，属于来源于植物的医药配制品：其特征在于以丹参、黄芪、当归、党参、枸杞的提取物为有效成分，包括原料筛选、煎煮、浓缩、蒸干、粉碎、配料、加辅料、灭菌、包装等步骤制成。本发明主治月经下调、痛经、黄褐斑及老年斑，具有抚元固本、活血化瘀、调经祛斑等功效，特别是调经祛斑治疗效果最为明显，有效率达95%以上。
Description
本发明涉及一种能调经祛斑的中药及其制备方法，属于来源于植物的医药配制品。
祖国传统医学认为，气血不足、气滞血瘀是许多病症的重要致病因素之一，***痛经，经血量过多或过少，周期紊乱特别是已往不被重视的面部色斑(黄褐斑、雀斑、老年斑等)已成为当今妇女的头号“疾病”，都是人群特别是妇女的常见病症和多发病症之一，患者由此而遭受着痛苦和烦恼，影响生活、学习和工作。现有的药物对上述所提及的***和面部褐色斑经常并发且有密切联系的病症不能兼治，因此设计、研制此类药物便显得十分必要。
本发明的目的是根据中医补益和活血化瘀理论与现代医学研究已证明的：色斑形成与体内多种自由基生成有关这一学说相结合；并将调经与祛斑联系在一起辩证施治而研制出具有抚元固本、活血化瘀、调经祛斑功能的中药制剂。
本发明的目的是通过如下方式来达到：中药制剂各组分的比例为：
以黄芪、丹参、当归、党参原料药的组成作为百分之百(100％)，则各组的百分比分别为：黄芪：24～32％、丹参：24～32％、当归：20～25％、党参：20～25％。
经煎煮后4味药的干粉作为百分之百(100％)，则按下述比例分别加入枸杞醇提物(粉)：2～10％、锌化物(以锌计)：0．1～1．0％、硒化物(以硒计)：0．1～4．0％。
其制备方法为：
按重量的百分比加入下述中药，将丹参、当归、黄芪、枸杞和党参经原料筛选、清洗后各加水、加热煎煮两遍，第一次2小时，第二次1小时，上清液回流浓缩成膏。枸杞的加工方法则采用醇提法，即用40％乙醇浸泡48小时，加热回流煎煮提取2小时后，弃掉沉渣，上清提取液继续环流加热浓缩抽干。然后蒸气干燥，干燥温度为80℃，时间60小时，再粉碎成细粉状按重量的百分比加入药干粉，微量元素，填加辅料，混匀，装胶囊，包装，钴源照射杀菌，质检，出品。
附图为本发明制备工艺流程图：
以下结合实施例作进一步说明：
取黄芪125g、丹参125g、当归100g、党参100g、经加水1500ml，煎锅温火煎煮2小时，过滤出上清液，药渣再加水1000ml，煎煮1小时，再用100目筛布滤出上清液，两上清液混合浓缩，80℃蒸气烘干。
再取宁夏枸杞100g、40％乙醇浸泡48小时，磨碎取上清液回收乙醇，烘干。
将上述两种干粉混合，按180∶1和90000∶1的比例分别加入乳酸锌和硒化物，粉碎。按10∶1的比例中入药用淀粉，混匀，装成胶囊或压片0．3克／粒。
本发明具有如下优点：
1．安体补益、调气养血可显著提高机体抗病能力免疫力，加速由于各种病症引起的体虚乏力的恢复，使人体处在健康水平，提高学习劳动、训练和工作能力。
2．具有调解内分泌失调引起的病症，如***、痛经等。
3．采用现代自由基生物学的筛选方法进行筛选，组方、论证，使本发明中药制剂为高效复合自由基清除剂(或抗氧化剂)，从而有效地阻止了过氧化物和变性蛋白结合而导致在皮肤和脏腑细胞内沉着引起的各种色斑(黄褐斑、老年斑等)。
4．调经与祛斑兼治，而各自的疗效均非常显著。
Claims (2)
1、调经祛斑胶囊，其特征在于取黄芪24—32％、丹参24—32％、当归20—25％、党参20—25％制成水提干粉，将该干粉与40％乙醇浸泡枸杞回流提取的干粉按1∶0．02—0．10混合，再将该混合物与以硒计的硒化物和以锌计的锌化物分别按90000∶1和180∶1的比例混合均匀，加入赋形剂，装胶囊即得。
2、权利要求1所述的调经祛斑胶囊的制备方法是：将黄芪、当归、丹参和党参经原料筛选、清洗后各加水煎煮两遍，第一次2小时、第二次1小时，上清液加热浓缩成膏，枸杞子用40％的乙醇浸泡48小时、加热回流提取2小时后，弃掉沉渣，上清继续回流加热浓缩抽干成膏，然后，水提和醇提膏经80℃蒸气干燥60小时，再粉碎成细粉状，混匀，包装即成。
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| CN95113742A CN1060349C (zh) | 1995-09-07 | 1995-09-07 | 调经祛斑胶囊及其制备方法 |
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| CN95113742A CN1060349C (zh) | 1995-09-07 | 1995-09-07 | 调经祛斑胶囊及其制备方法 |
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| CN1144671A CN1144671A (zh) | 1997-03-12 |
| CN1060349C true CN1060349C (zh) | 2001-01-10 |
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| CN95113742A Expired - Fee Related CN1060349C (zh) | 1995-09-07 | 1995-09-07 | 调经祛斑胶囊及其制备方法 |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101352497B (zh) * | 2007-07-26 | 2011-11-09 | 株洲千金药业股份有限公司 | 一种祛黄褐斑的中药组合物、其制备方法及其用途 |
| CN102688352A (zh) * | 2012-06-13 | 2012-09-26 | 王尤龙 | 一种治疗痛经的中药组方 |
| CN103202480A (zh) * | 2013-05-03 | 2013-07-17 | 高益槐 | 一种祛斑美容功能的保健食品及其制备方法 |
| CN106581395B (zh) * | 2017-02-03 | 2019-12-06 | 兰州大学 | 一种具有抗氧化功能的复方药物及其制备方法 |
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1995
- 1995-09-07 CN CN95113742A patent/CN1060349C/zh not_active Expired - Fee Related
Non-Patent Citations (3)
| Title |
|---|
| 中药材90年第2期 1990.2.28 罗丙锵中药微量原素的作用 * |
| 实用中西医结合杂志92年第2期 1992.2.28 孙小利中西医结合治疗***症 * |
| 实用中西医结合杂志92年第2期 1992.2.28 孙小利中西医结合治疗***症;中药材90年第2期 1990.2.28 罗丙锵中药微量原素的作用 * |
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