A kind of biological sample conveying and detecting system
Technical field
The present invention relates to the conveying of a kind of biological sample and detecting system, including the test tube taking up biological sample such as blood, urine
Conveyer device and the follow-up detection terminal carrying out biology sample detection, particularly relate to a kind of urine test tube automatic conveying device, belong to
In B65G field.
Background technology
In the package packing machine industry such as food, pharmacy, various medicine container containings, such as: cillin bottle, ampoule bottle,
Oral liquid bottle, infusion bottle etc. have obtained universal utilization.In above-mentioned bottle, most bottleneck is less than the diameter of body,
When carrying said structure bottle, only need directly to realize the conveying to bottle, namely by bottle by various Belt Drive
Body is placed on the conveyer belt of motion, carries bottle by the frictional force produced between at the bottom of conveyor belt surface and bottle.But, this
A little bottle conveying mechanisms but cannot apply in the bottle conveying of medical treatment biological sample, when running into the bottle that bottleneck is bigger than body diameter
During body, if using conventional mode of movement conveying, it is easy for causing more serious " emitting bottle " and " bottle " phenomenon.As
In the medical field, its bottleneck of test tube taking up biological sample such as blood, urine is just big than body diameter, and uses and manually remove
The mode of fortune obviously wastes time and energy.
Additionally, in the biology sample detection field detecting urine etc., any one color can be come with RGB
Representing, rgb color pattern is a kind of color standard of industrial quarters, is by leading to red (R), green (G), blue (B) three colors
The change in road and their superpositions each other obtain color miscellaneous, and RGB is i.e. to represent red, green, blue three
The color of individual passage, this standard almost include human eyesight can all colours of perception, be to use the widest face at present
One of colour system system.Rgb color pattern RGB model is that the RGB component of each pixel in image distributes one 0~255
In the range of intensity level.Such as: pure red R value is 255, G-value is 0, and B value is 0;R, G, B of Lycoperdon polymorphum Vitt tri-
It is worth equal (except 0 and 255);R, G, B of white are 255;R, G, B of black is 0.RGB image
Only use three kinds of colors, so that it may so that they are according to different ratio mixing, screen reappears 16777216 kinds of colors.And
Human eye is the finest and complicated to the identification of color and shade, and it can pick out thousands of kinds of colors, but can only divide
Debate do not go out 4-6Bit gray scale aberration (list of references: " China stereology and graphical analysis " in JIUYUE, 2002, volume 7,
3rd phase " Pseudo Col ored Image of medical image ").
The detection project that a lot of medical science are relevant can be detected with certain by the optical characteristics or sample of measuring detection sample itself
Reagent, such as such as immunochromatographiassay assay reagent, dry chemistry detectable, chemiluminescence detection reagent, optical characteristics after reaction
Change and obtain, some dependence gross visualization carry out sentence read result, and some use instrumentations carry out quantitative interpretation result, aobvious
So gross visualization lacks accuracy and concordance, and existing most of instrumentation exists the problems such as cost height, convenience difference.
The smart mobile phone having at present to have camera function and panel computer replace special instrument to read detection target, and this scheme drops
Low cost, improves the convenience of use, but the difference of individual type, the difference of photoenvironment, photo angle and distance
Difference and the factor such as hand tremor all can affect the accuracy of testing result.
At present in the urgent need to need to look for a kind of collect conveying, the biological sample that is detected on one carries and detecting system..
Summary of the invention
In order to overcome the defect of prior art, an object of the present invention is to provide a kind of biological sample conveying and detecting system,
It includes test tube conveying device and portable field detection terminal.
The present invention also aims to provide a kind of simple and compact for structure, with low cost, can accept have suspended structure test tube,
Active conveying bottle is reliable and stable and the adjustable test tube conveying device of active conveying bottle speed.
The present invention also aims to provide a kind of portable field detection terminal and method, can be greatly reduced and use into
This, improve property easy to use, can keep again accuracy and the concordance of specialty detection equipment.
For solve above-mentioned technical problem, the present invention by the following technical solutions:
A kind of biological sample conveying and detecting system, it includes test tube conveying device and portable field detection terminal.
A kind of test tube conveying device, the guide assembly including frame and being fixed in frame and test tube drive assembly, described in lead
Rail assembly includes the test tube containing cavity arranged along the test tube direction of motion and is positioned at the bottleneck suspension part above test tube containing cavity, institute
Stating test tube drives assembly to be positioned at the lower section of test tube containing cavity and by producing the driving force of test tube motion with test tube friction.
As a further improvement on the present invention:
Described test tube drives assembly to include pressing plate and the conveyer belt being set around on synchronous pulley, and described pressing plate and conveyer belt are symmetrically
Shape is arranged in the both sides of test tube.
Described frame is provided with more than one piece and provides the adjustable plate towards test tube direction thrust for pressing plate.
Offering mounting hole on described adjustable plate, described adjustable plate is fixed on frame by the clamping screw being arranged in mounting hole
On.
On described pressing plate, the one side towards test tube is provided with elastic pressure section.Additionally, the present invention also provides for a kind of portable field
Detection terminal, it include on and off switch, battery cavities, upper and lower cover connection strap, main control board, upper cover, camera bracket,
Supply hub, test card jack, lower cover, image-generating unit.
Further, described image-generating unit has shell, inside to arrange photographic head, camera bracket, circuit board, described shooting
Head bracket is two, is correspondingly arranged at the both sides of described interior forward end, and described battery compartment is arranged on described Internal back end, described
Photographic head arranges the top of two described camera brackets, and described circuit board is arranged on the upper of described battery compartment and described photographic head
Side.
Further, the shell of described image-generating unit includes that upper cover, middle cover and lower cover, described upper cover include end face and four
Side, described lower cover includes bottom surface and four sides, and described middle cover includes a side and peripheral frame, the side of described middle cover
Covering with described upper cover and lower cover respectively, the peripheral frame of described middle cover covers with the side of described upper cover and described lower cover, described
Being provided with reagent card socket on the side of middle cover, described reagent card spigot inserts detection target holder.
Further, the upper end face of described upper cover is provided with instrument switch hole, is provided with described instrument in described instrument switch hole
Switch, described switch is connected with described circuit board.
Further, it is provided with external power supply jack in the side of described lower cover, with described battery in described external power supply jack
Storehouse connects, and the bottom surface at described lower cover is provided with battery cabin cap.
Further, described image-generating unit also includes bluetooth equipment.
Its also include manipulating unit and image analyzing unit and portable field detection terminal with the use of, portable field detects
Terminal is spatially separated from manipulation unit and image analyzing unit, and image-generating unit and manipulation unit are by Near Field Communication method
Being connected, manipulation unit is connected by network communication method with image analyzing unit, and image-generating unit is used for shot detection target, figure
As analytic unit is for analyzing the digital picture clapped and drawing testing result, manipulation unit is used for manipulating whole detection instrument.
Main operational principle is that by image-generating unit, detection card is gathered image, and image-generating unit sends images to manipulate unit example
As mobile phone or pad etc. have on reception and transfer function instrument or equipment, accepted by the APP on mobile phone or pad
The image that image-generating unit sends over, uploads to image analyzing unit such as cloud computer, claps according to cloud computer analysis
Digital picture also draws testing result, finally feeds back on mobile phone or pad quickly to draw the result of detection.
Image-generating unit herein can also be any image-generating unit known in the art, the most excellent this tech advanced in years.
Advantages of the present invention:
Compared with prior art, it is an advantage of the current invention that: the test tube conveying device of the present invention, simple and compact for structure, cost
Cheap, by suspension part that test tube is mounted on guide assembly, and under test tube drives the frictional force of assembly to drive
Realizing the conveying of test tube, reliable and stable and active conveying bottle speed the regulation of active conveying bottle is very convenient.The detection device of the present invention then has:
1, remote control and regulation, it is simple to management.Traditional detection instrument needs to detect sample and analytical tool near work, present invention achieves sample
Acquisition instrument separates with data analyzer, realizes the long-range detection to sample by network data base.Additionally, also may be used in network data backstage
To utilize standard color comparison card that every sample collection instrument is carried out remote calibration, prevent the error caused because of ageing equipment.2, cost-effective.
Under the management on unified backstage, have only to sample collection instrument during detection, can be achieved with the detection of many index, with traditional a complete set of test
Instrument is compared and is greatly saved cost.
Accompanying drawing explanation
Fig. 1 is present invention perspective view in application example;
Fig. 2 is present invention plan structure schematic diagram in application example.
Fig. 3 be a kind of digital image detection of the present invention be the structural representation of instrument;
Fig. 4 be a kind of digital image detection of Fig. 3 be the internal structure schematic diagram of instrument;
Fig. 5 is test card schematic diagram;
Fig. 6 is that the collection obtained according to cloud database goes out to test image;
Fig. 7 is the position searching out test card test reference line;
Fig. 8 is the reagent card before and after sample-adding;
Fig. 9 is the image collecting device inserting reagent card;
Figure 10 is that mobile phone A PP opens interface.
Detailed description of the invention
In order to make the purpose of the present invention, technical scheme and advantage are clearer, below in conjunction with drawings and Examples, to this
Invention is further elaborated;Should be appreciated that specific embodiment described herein only in order to explain the present invention, not
For limiting the present invention.
Embodiment
As depicted in figs. 1 and 2, a kind of biological sample conveying and detecting system, it includes test tube conveying device and portable existing
Detection terminal, the wherein test tube conveying device of the present invention, including frame 10 and be fixed on the guide assembly in frame 10
1 and test tube drive assembly, guide assembly 1 include along test tube 5 direction of motion arrange test tube containing cavity 101 and be positioned at examination
Bottleneck suspension part 102 above pipe containing cavity 101, test tube drive assembly be positioned at test tube containing cavity 101 lower section and by with
Test tube 5 friction produces the driving force of test tube motion.The bottle-delivery end of guide assembly 1 can be connected with thumb wheel 9 or other bottle-conveying mechanisms,
Test tube containing cavity 101 is enclosed to set by some blocks of plates and forms.
In the present embodiment, test tube drives assembly to include pressing plate 6 and the conveyer belt 7 being set around on synchronous pulley 11, pressing plate 6
With the both sides that conveyer belt 7 symmetrically shape is arranged in test tube 5, synchronous pulley 11 being rotated by thus with biography at actuator
Sending band 7 motion, conveyer belt 7 contacts generation frictional force and drives test tube 5 to transport forward along test tube containing cavity 101 with test tube 5
Dynamic.On pressing plate 6, the one side towards test tube 5 is provided with elastic pressure section 8.
Frame 10 is provided with more than one piece and provides the adjustable plate 12 towards test tube 5 direction thrust for pressing plate 6.Adjustable plate 12
On offer mounting hole 3, adjustable plate 12 is fixed in frame 10 by the clamping screw 2 being arranged in mounting hole 3, can
Regulate the distance between pressing plate 6 and conveyer belt 7 by mounting hole 3, so adjustable plate 12 to the thrust size of pressing plate 6 with
And the size of the frictional force produced between regulation conveyer belt 7 and test tube 5.The direction that mounting hole 13 is offered and the motion of test tube 5
Direction is vertical.
As shown in Figure 3-4, it is biological sample conveying and the portable field detection terminal of detecting system of the present invention, including becoming
As unit, manipulation unit and image analyzing unit, described image-generating unit, manipulation unit and image analyzing unit spatially divide
From, image-generating unit is connected by Near Field Communication method with manipulation unit, and manipulation unit is led to by network with image analyzing unit
Communication method is connected, and image-generating unit is used for shot detection target, and image analyzing unit is for analyzing the digital picture clapped and drawing
Testing result, manipulation unit is used for manipulating whole detection instrument.
Further, described image-generating unit has shell, inside to arrange photographic head, camera bracket 8, circuit board 7 and battery
Storehouse 6, described camera bracket 8 is two, is correspondingly arranged at the both sides of described interior forward end, and described battery compartment 6 is arranged on
Described Internal back end, described photographic head is arranged on the top of two described camera brackets 8, and described circuit board 7 is arranged on institute
State battery compartment 6 and the top of described photographic head.
Further, the shell of described image-generating unit includes that upper cover 3, middle cover 2 and lower cover 5, described upper cover 3 include end face
With four sides, described lower cover 5 includes bottom surface and four sides, and described middle cover 2 includes a side and peripheral frame, described
The side of middle cover 2 covers with described upper cover 3 and lower cover 5 respectively, the peripheral frame of described middle cover 2 and described upper cover 3 and described under
The side of lid 5 covers, and is provided with reagent card socket 9 on described middle cover 2 side, inserts inspection at described reagent card socket 9
Survey target holder.
Further, the upper end face of described upper cover 3 is provided with instrument switch hole 1, has arranged in described instrument switch hole 1
Stating the switch of instrument, described switch is connected with described circuit board 7.
Further, it is provided with external power supply jack 4 in the side of described lower cover 5, in described external power supply jack 4 and institute
Stating battery compartment 6 to connect, the bottom surface at described lower cover 5 is provided with battery cabin cap.
Further, described image-generating unit also includes bluetooth equipment, and described image-generating unit is by described bluetooth equipment and described behaviour
Control unit is connected.
Further, described control unit is mobile phone, and mobile phone is provided with APP, and mobile phone A PP passes through Bluetooth control imaging list
Unit carries out image acquisition to sample.
Further, described image analyzing unit is cloud computer.
Example one detects interstitialcellstimulating hormone (ICSH) (LH) concentration in women body
1., by 3 vertical droppings of urina sanguinis on LH reagent card, candidate agent card inserts in image-generating unit after reacting 15 minutes.
2. mobile phone A PP is opened, and by bluetooth, mobile phone is bound with image-generating unit, click on standing on mobile phone interface
I.e. testing, test starts, and test philosophy is as follows:
Reagent card enters in the coverage of test photographic head, and instrument carries out the image acquisition of reagent card.The image collected
Being sent to cloud computer by network, the latter utilizes face recognition technology to process image.
The first step is automatically found the long limit of test card observation port, starts Automatic-searching from interface 0,0 location of pixels of photographic head,
Utilize the color change feature of immunological test card film and plastic testing card shell, determine the position letter on the long limit of observation port of test card
Breath, to determine the upper edge (Fig. 5) of test picture collection, further according to collecting test card figure corresponding in cloud database
Sheet width information, gathers out test image (Fig. 6).
Second step, on the basis of finding the test long limit of card observation port and collecting test image, utilizes image face recognition technology,
On image from right to left Automatic-searching test card test reference line position, if Automatic-searching beyond searching scope time the most not
Finding test reference line, (test definition of immune chromatograph testing card is without test ginseng to be just defined as this test crash
Examine line and appear as this test crash);Otherwise (figure is found at the edge, peak to response line (including reference line and p-wire)
5), image software carries out tangent line calculating to edge, peak, according to edge, peak in response line (including reference line and p-wire) position
The rate of change of tangent line finds the beginning and end of response line (including reference line and p-wire).(reference line is included at response line
And p-wire) beginning and end region color is carried out layered method RGB unit are meansigma methods, deduct background, meter
Calculate real RGB numerical value, further according to standard gray angle value equation, RGB numerical range and RGB computing formula, finally count
Calculate the GOD value of correspondence.
3., after test terminates, from mobile phone A PP, read LH test result.
Example two: detection human chorionic gonadotropin concentration
1., by 3 vertical droppings of urina sanguinis on HCG type agents card, candidate agent card inserts excellent stepping in this tech after reacting 15 minutes
(Fig. 8 is the reagent card before and after sample-adding, and Fig. 9 is excellent this tech advanced in years of image collecting device inserting reagent card).
2. mobile phone A PP is opened (interface such as Figure 10), and by bluetooth, mobile phone is bound with excellent this tech that steps, click on " vertical
I.e. test ", test starts.
3., after test terminates, read HCG test result by mobile phone A pp.