CN105999109A - 一种治疗高血脂的中药组合物 - Google Patents
一种治疗高血脂的中药组合物 Download PDFInfo
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Abstract
本发明公开了一种治疗高血脂的中药组合物,属于中药技术领域。解决了现有药物易反复的问题,其由以下中药原料组成:马齿苋1‑3份,松节1‑3份,延胡索2‑6份,莱菔子3‑8份,化橘红6‑10份,百合5‑10份,菟丝子8‑12份,天门冬10‑15份,石斛5‑10份,五味子10‑15份,郁金1‑5份,竹茹8‑12份,茯苓10‑15份,甘草2‑6份,玫瑰花1‑5份,远志10‑15份,牛黄2‑6份,丹参1‑3份,沙苑子10‑15份,瓜蒌1‑3份,金银花3‑8份,桑叶6‑10份,绞股蓝1‑5份,仙茅10‑15份,泽泻10‑15份,决明子3‑5份,玉米须8‑12份,川楝子5‑10份。本发明适合高血脂患者使用。
Description
技术领域
本发明涉及一种治疗高血脂的中药组合物,属于中药技术领域。
背景技术
高血脂症是指人体血浆一种或数种脂质成分的含量超过正常最高值限。本病在营养代谢性疾患中占有很重要的地位,是导致动脉粥样硬化的主要因素之一,与高血压、冠心病和脑血管病的***密切,被视为冠心病的叁大因子之一。在我国,高血脂症并不罕见,近年来其患病率及死亡率还有逐年增高的趋势,尤其多见于中、老年人。本病原发性病因未明,多有家族史及遗传史。现代医学虽有多种降脂药物,但多有副作用且疗效不稳定。
中医古文献虽无“血脂”之名称,但在《黄帝内经》中已有“脂者”、“油脂”、“脂膜”等记载。如《灵枢·卫气失常》篇说:“脂者,其血清,气滑少。”这是最早论及脂者的记载。现代中医认为高血脂多因偏食、恣食肥甘厚味或嗜酒成癖,以致脾胃受损,运化失健,聚湿生痰,痰从浊化。
发明内容
本发明的目的在于提供一种治疗高血脂的中药组合物,疗程短,疗效好。
所述的治疗高血脂的中药组合物,由以下重量份的中药原料组成:
马齿苋1-3份,松节1-3份,延胡索2-6份,莱菔子3-8份,化橘红6-10份,百合5-10份,菟丝子8-12份,天门冬10-15份,石斛5-10份,五味子10-15份,郁金1-5份,竹茹8-12份,茯苓10-15份,甘草2-6份,玫瑰花1-5份,远志10-15份,牛黄2-6份,丹参1-3份,沙苑子10-15份,瓜蒌1-3份,金银花3-8份,桑叶6-10份,绞股蓝1-5份,仙茅10-15份,泽泻10-15份,决明子3-5份,玉米须8-12份,川楝子5-10份。
所述的治疗高血脂的中药组合物,由以下重量份的中药原料组成:
马齿苋2份,松节2份,延胡索4份,莱菔子5份,化橘红8份,百合8份,菟丝子10份,天门冬12份,石斛8份,五味子12份,郁金3份,竹茹10份,茯苓12份,甘草4份,玫瑰花3份,远志12份,牛黄4份,丹参2份,沙苑子12份,瓜蒌2份,金银花5份,桑叶8份,绞股蓝3份,仙茅12份,泽泻12份,决明子4份,玉米须10份,川楝子8份。
各中药作用机理:
马齿苋:酸,寒。归肝、大肠经。功能主治清热解毒,凉血止血。用于热毒血痢,痈肿疔疮,湿疹,丹毒,蛇虫咬伤,便血,痔血,崩漏下血。
松节:苦,温。功能主治:祛风除湿,活络止痛。用于风湿关节痛,腰腿痛,大骨节病,跌打肿痛。
延胡索:辛、苦,温。归肝、脾经。功能与主治:活血,行气,止痛。用于胸胁、脘腹疼痛,胸痹心痛,经闭痛经,产后瘀阻,跌扑肿痛。
莱菔子:辛、甘,平。归肺、脾、胃经。功能与主治:消食除胀,降气化痰。用于饮食停滞,脘腹胀痛,大便秘结,积滞泻痢,痰壅喘咳。
化橘红:辛、苦,温。归肺、脾经。功能与主治:理气宽中,燥湿化痰。用于咳嗽痰多,食积伤酒,呕恶痞闷。
百合:甘,寒。归心、肺经。功能与主治:养阴润肺,清心安神。用于阴虚燥咳,劳嗽咳血,虚烦惊悸,失眠多梦,精神恍惚。
菟丝子:辛、甘,平。归肝、肾、脾经。功能与主治:补益肝肾,固精缩尿,安胎,明目,止泻;外用消风祛斑。用于肝肾不足,腰膝酸软,阳痿遗精,遗尿尿频,肾虚胎漏,胎动不安,目昏耳鸣,脾肾虚泻;外治白癜风。
天门冬:甘苦,寒。入肺、肾经。功能主治:滋阴,润燥,清肺,降火。治阴虚发热,咳嗽吐血,肺痿,肺痈,咽喉肿痛,消渴,便秘。
石斛:甘,微寒。归胃、肾经。功能与主治:益胃生津,滋阴清热。用于热病津伤,口干烦渴,胃阴不足,食少干呕,病后虚热不退,阴虚火旺,骨蒸劳热,目暗不明,筋骨痿软。
五味子:酸、甘,温。归肺、心、肾经。功能与主治:收敛固涩,益气生津,补肾宁心。用于久嗽虚喘,梦遗滑精,遗尿尿频,久泻不止,自汗盗汗,津伤口渴,内热消渴,心悸失眠。
郁金:辛、苦,寒。归肝、心、肺经。功能与主治:活血止痛,行气解郁,清心凉血,利胆退黄。用于胸胁刺痛,胸痹心痛,经闭痛经,***胀痛,热病神昏,癫痫发狂,血热吐衄,黄疸尿赤。
竹茹:性微寒,味甘。功能主治:清热化痰,除烦止呕。用于痰热咳嗽、胆火挟痰、烦热呕吐、惊悸失眠、中风痰迷、舌强不语、胃热呕吐、妊娠恶阻、胎动不安。
茯苓:甘、淡,平。归心、肺、脾、肾经。功能与主治:利水渗湿,健脾,宁心。用于水肿尿少,痰饮眩悸,脾虚食少,便溏泄泻,心神不安,惊悸失眠。
甘草:甘,平。归心、肺、脾、胃经。功能与主治:补脾益气,清热解毒,祛痰止咳,缓急止痛,调和诸药。用于脾胃虚弱,倦怠乏力,心悸气短,咳嗽痰多,脘腹、四肢挛急疼痛,痈肿疮毒,缓解药物毒性、烈性。
玫瑰花:甘、微苦,温。归肝、脾经。功能与主治:行气解郁,和血,止痛。用于肝胃气痛,食少呕恶,月经不凋,跌扑伤痛。
远志:苦、辛,温。归心、肾、肺经。功能与主治:安神益智,交通心肾,祛痰,消肿。用于心肾不交引起的失眠多梦、健忘惊悸、神志恍惚,咳痰不爽,疮疡肿毒,***肿痛。
牛黄:甘,凉。归心、肝经。功能与主治:清心,豁痰,开窍,凉肝,息风,解毒。用于热病神昏,中风痰迷,惊痫抽搐,癫痫发狂,咽喉肿痛,口舌生疮,痈肿疔疮。
丹参:苦,微寒。归心、肝经。功能与主治:活血祛瘀,通经止痛,清心除烦,凉血消痈。用于胸痹心痛,脘腹胁痛,瘕瘕积聚,热痹疼痛,心烦不眠,***,痛经经闭,疮疡肿痛。
沙苑子:甘,温。归肝、肾经。功能与主治:补肾助阳,固精缩尿,养肝明目。用于肾虚腰痛,遗精早泄,遗尿尿频,白浊带下,眩晕,目暗昏花。
瓜蒌:甘、微苦,寒。归肺、胃、大肠经。功能与主治:清热涤痰,宽胸散结,润燥滑肠。用于肺热咳嗽,痰浊黄稠,胸痹心痛,结胸痞满,乳痈,肺痈,肠痈,大便秘结。
金银花:甘,寒。归肺、心、胃经。功能与主治:清热解毒,疏散风热。用于痈肿疗疮,喉痹,丹毒,热毒血痢,风热感冒,温病发热。
桑叶:甘、苦,寒。归肺、肝经。功能与主治:疏散风热,清肺润燥,清肝明目。用于风热感冒,肺热燥咳,头晕头痛,目赤昏花。
绞股蓝:性寒,味苦。功能主治:消炎解毒,止咳祛痰。现多用作滋补强壮药。
仙茅:辛,热;有毒。归肾、肝、脾经。功能与主治:功在温肾壮阳,散寒除湿。主治阳痿精寒,小便失禁,遗尿,崩漏,寒湿痹痛,腰膝酸软,胃腹冷痛;近用于治更年期高血压症,更年期综合征,血清胆固醇过高症。
泽泻:甘、淡,寒。归肾、膀胱经。功能与主治:利水渗湿,泄热,化浊降脂。用于小便不利,水肿胀满,泄泻尿少,痰饮眩晕,热淋涩痛,高脂血症。
决明子:甘、苦、咸,微寒。归肝、大肠经。功能与主治:清热明目,润肠通便。用于目赤涩痛,羞明多泪,头痛眩晕,目暗不明,大便秘结。
玉米须:味甘;淡;性平。归肾;胃;肝;胆经。功能主治:利尿消肿;清肝利胆。主水肿;小便淋沥;黄疸;胆囊炎;胆结石;高血压;糖尿病;乳汁不通。
川楝子:苦,寒;有小毒。归肝、小肠、膀胱经。功能与主治:疏肝泄热,行气止痛,杀虫。用于肝郁化火,胸胁、脘腹胀痛,疝气疼痛,虫积腹痛。
与现有技术相比本发明的有益效果是:
本发明以中医理论为基础,配伍科学,用药合理,使用安全无毒副作用,诸药合用具有清热解毒、化痰祛湿、疏肝解郁、健脾益胃、滋阴生津、补气养血、舒筋活络等功效,通过调理肝、胆、脾、胃、肾以达到治愈高血脂的目的,同时本发明对高血压、高血糖、心脑血管等疾病均有辅助疗效,本发明可有效快速的治愈高血脂,总治愈率95%,总有效率99%。
下面结合临床试验和典型病例对本发明作进一步说明。
一、临床试验:
1、临床资料:
随机选取高血脂患者100例,其中男性67名,女性33名,年龄在32到76岁之间,血脂检测显示血浆总胆固醇>6.2mmol/L,血浆甘油三酯>2.3mmol/L,并伴有肥胖,形神衰退,头昏头晕,耳鸣,腰膝酸软,形寒怕冷,手足欠温,腹胀纳呆,肠鸣便溏,胸闷,少腹或胁肋胀痛等症状。
2、治疗方法:
本发明中药组合物每日一剂,水煎服,分早晚两次饭后服用,5天1疗程,一般用药3个疗程。
3、疗效标准:
痊愈:血脂检测正常,伴随症状消失;
有效:血脂检测趋于正常,伴随症状减轻;
无效:各临床症状无改善。
4、治疗结果:
100例高血脂患者,在服药3个疗程后,95人痊愈,4人有效,1人无效,总治愈率95%,总有效率99%,随访一年无复发患者。
典型病例:
李某,52岁,男,220多斤,肥胖,啤酒肚,血脂检测显示血浆总胆固醇>6.2mmol/L,血浆甘油三酯>2.3mmol/L,并伴有神疲乏力,头晕耳鸣,腰膝酸软,曾使用多种方法治疗,均治标不治本,停药反复,使用本发明中药组合物1个疗程,感觉精力充沛、腰膝有劲了,用药3个疗程检测显示血浆总胆固醇5.0mmol/L,血浆甘油三酯1.6mmol/L,而且体重减轻了20多斤,伴随症状完全消失,随访一年无复发,体重维持在150斤左右。
朱某,女,46岁,血脂检测显示血浆总胆固醇>6.2mmol/L,血浆甘油三酯>2.3mmol/L,伴有情绪不宁,善叹息,脘痞嗳气,泛酸苦水,***,经前乳胀、腹痛。曾使用多种方法治疗,均治标不治本,停药反复,使用本发明中药组合物1个疗程,情绪稳定,口泛酸水等症状好转,用药3个疗程检测显示血浆总胆固醇4.8mmol/L,血浆甘油三酯1.7mmol/L,伴随症状完全消失,随访一年无复发。
具体实施方式
下面结合具体实施例对本发明做进一步说明。
实施例1
所述的治疗高血脂的中药组合物,由以下重量份的中药原料组成:
马齿苋1份,松节1份,延胡索2份,莱菔子3份,化橘红6份,百合5份,菟丝子8份,天门冬10份,石斛5份,五味子10份,郁金1份,竹茹8份,茯苓10份,甘草2份,玫瑰花1份,远志10份,牛黄2份,丹参1份,沙苑子10份,瓜蒌1份,金银花3份,桑叶6份,绞股蓝1份,仙茅10份,泽泻10份,决明子3份,玉米须8份,川楝子5份。
实施例2
所述的治疗高血脂的中药组合物,由以下重量份的中药原料组成:
马齿苋2份,松节2份,延胡索4份,莱菔子5份,化橘红8份,百合8份,菟丝子10份,天门冬12份,石斛8份,五味子12份,郁金3份,竹茹10份,茯苓12份,甘草4份,玫瑰花3份,远志12份,牛黄4份,丹参2份,沙苑子12份,瓜蒌2份,金银花5份,桑叶8份,绞股蓝3份,仙茅12份,泽泻12份,决明子4份,玉米须10份,川楝子8份。
实施例3
所述的治疗高血脂的中药组合物,由以下重量份的中药原料组成:
马齿苋3份,松节3份,延胡索6份,莱菔子8份,化橘红10份,百合10份,菟丝子12份,天门冬15份,石斛10份,五味子15份,郁金5份,竹茹12份,茯苓15份,甘草6份,玫瑰花5份,远志15份,牛黄6份,丹参3份,沙苑子15份,瓜蒌3份,金银花8份,桑叶10份,绞股蓝5份,仙茅15份,泽泻15份,决明子5份,玉米须12份,川楝子10份。
Claims (2)
1.一种治疗高血脂的中药组合物,其特征在于由以下重量份的中药原料组成:
马齿苋1-3份,松节1-3份,延胡索2-6份,莱菔子3-8份,化橘红6-10份,百合5-10份,菟丝子8-12份,天门冬10-15份,石斛5-10份,五味子10-15份,郁金1-5份,竹茹8-12份,茯苓10-15份,甘草2-6份,玫瑰花1-5份,远志10-15份,牛黄2-6份,丹参1-3份,沙苑子10-15份,瓜蒌1-3份,金银花3-8份,桑叶6-10份,绞股蓝1-5份,仙茅10-15份,泽泻10-15份,决明子3-5份,玉米须8-12份,川楝子5-10份。
2.根据权利要求1所述的治疗高血脂的中药组合物,其特征在于由以下重量份的中药原料组成:
马齿苋2份,松节2份,延胡索4份,莱菔子5份,化橘红8份,百合8份,菟丝子10份,天门冬12份,石斛8份,五味子12份,郁金3份,竹茹10份,茯苓12份,甘草4份,玫瑰花3份,远志12份,牛黄4份,丹参2份,沙苑子12份,瓜蒌2份,金银花5份,桑叶8份,绞股蓝3份,仙茅12份,泽泻12份,决明子4份,玉米须10份,川楝子8份。
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