CN105997127A - Static mammary gland dual-energy CT imaging system and method - Google Patents
Static mammary gland dual-energy CT imaging system and method Download PDFInfo
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- CN105997127A CN105997127A CN201610448855.XA CN201610448855A CN105997127A CN 105997127 A CN105997127 A CN 105997127A CN 201610448855 A CN201610448855 A CN 201610448855A CN 105997127 A CN105997127 A CN 105997127A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/02—Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
- A61B6/03—Computerised tomographs
- A61B6/032—Transmission computed tomography [CT]
- A61B6/035—Mechanical aspects of CT
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/40—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for generating radiation specially adapted for radiation diagnosis
- A61B6/4021—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for generating radiation specially adapted for radiation diagnosis involving movement of the focal spot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/44—Constructional features of apparatus for radiation diagnosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/50—Clinical applications
- A61B6/502—Clinical applications involving diagnosis of breast, i.e. mammography
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
- A61B6/5211—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
- A61B6/5258—Devices using data or image processing specially adapted for radiation diagnosis involving detection or reduction of artifacts or noise
Abstract
The invention is suitable for the field of CT imaging, and provides a static mammary gland dual-energy CT imaging system and method. The CT imaging system comprises an arc-shaped or broken-line-shaped mutli-focal-spot X light source device, a flat panel detector used for receiving X rays, a power supply device used for conducting high and low voltage power supply on the mutli-focal-spot X light source device and a processing device used for conducting image reconstruction; the mutli-focal-spot X light source device comprises at least one mutli-focal-spot X light source, each mutli-focal-spot X light source is provided with two or more emitting focal spots, the multiple mutli-focal-spot X light sources are connected and arranged end to end along an arc-shaped curve for conducting multi-angle irradiation on the mammary gland, and the flat panel detector and the mutli-focal-spot X light source device are right opposite to each other and perpendicularly bisected through the same straight line. According to the static mammary gland dual-energy CT imaging system and method, the mutli-focal-spot X light source device is adopted for replacing traditional multiple single-focal-spot X light sources to conduct dual-energy imaging, the mammary gland can be irradiated in an all-dimensional and static mode, potential motion artifacts are avoided, the detection accuracy and efficiency are improved, the cost is reduced, and the static mammary gland dual-energy CT imaging system is an ideal tool for mammary gland disease diagnosis.
Description
Technical field
The invention belongs to CT technical field of imaging, particularly to a kind of static mammary gland dual intensity CT imaging system and
Formation method.
Background technology
Breast carcinoma is one of modal malignant tumor of women.Early discovery, early diagnosis and early treatment's quilt
It is considered to control the effective measures of breast cancer development, and the survival rate and quality of life improving patient is had weight
The meaning wanted.CT imaging has high-resolution, sensitive to calcification pathological changes, space orientation accurate and can clearly show
Show the advantage of mammary gland anatomical structure, be a kind of ideal tools of early diagnosing mammary cancer.Existing CT system bag
Include monoenergetic CT and dual intensity CT, and for dual intensity CT more traditional monoenergetic CT, can not only realize dissecting knot
The detection of structure and location, also have Object Classification ability, is particularly suited for the clinic of breast carcinoma calcification in early days
Diagnosis.But tradition double-energy CT system still suffers from certain defect, for omnibearing imaging, need to rotate light source
Parts, so can increase operation complexity, increase cost and have potential motion artifacts, if using multiple light
Source adds cost the most undoubtedly, and cost control is the key factor affecting product development.
Summary of the invention
Present invention is primarily targeted at a kind of static mammary gland dual intensity CT imaging system of offer, it is intended to avoid turning
The potential motion artifacts that dynamic light source part causes, promotes precision and efficiency of detecting, and controls cost.
The present invention is achieved in that a kind of static mammary gland dual intensity CT imaging system, including arc or broken line
Many focal spots X source device of shape, after receiving and being sent by described many focal spots X source device and passed mammary gland
X-ray flat panel detector, for carrying out the confession of high pressure and low-voltage power supply for described many focal spots X source device
Electric installation, and for carrying out the processing means of image reconstruction；Described many focal spots X source device includes at least
Focal spot X source more than one, each many focal spots X source is provided with two or more and launches focus, multiple described multifocal
Speckle X source arcuately curve tandem array is arranged so that mammary gland to carry out multi-angle irradiation, described flat panel detector
With described many focal spots X source device just to and divided equally by same straight line is vertical.
Another object of the present invention is to provide a kind of static mammary gland dual intensity CT formation method, based on described
Static mammary gland dual intensity CT imaging system is implemented, and comprises the steps:
Control sequentially in time non-conterminous described transmitting focus respectively under high pressure and low pressure launch X penetrate
Line, receives the light energy after described X-ray passes mammary gland by described detector, obtains each transmitting focus
Original image corresponding under high pressure and low pressure；
Image reconstruction is carried out, particularly as follows: every width original image is processed, it is thus achieved that repair by processing means
Positive image, described correction map picture=log [(original image darkfield image)/(bright-field image darkfield image)], its
In, representing subtraction, log represents that operation of taking the logarithm, described darkfield image and bright-field image are for being pre-stored in
Data in described processing means；Then, carry out CT reconstruction based on whole described correction map pictures, obtain CT
Rebuild image.
The present invention uses multifocal X source device to substitute traditional multiple single focus X-ray light source, by one or many
Individual multifocal X source forms, and overall curved or fold-line-shaped, controls to launch focus one by one and launches X-ray,
Mammary gland can be irradiated the most from different perspectives, and then can be not required to comprehensive static illumination mammary gland
Rotate light supply apparatus, and then avoid potential motion artifacts, improve precision and efficiency of detecting；One multifocal X
Light source has multiple transmitting focus, is equivalent to multiple traditional X source, therefore can reduce X source in a large number
Quantity, and be significantly reduced to this；Multifocal X source combines high-low pressure dual-energy imaging, has both eliminated potential
Motion artifacts, promotes accuracy of detection and can carry out again qualitative analysis, be the ideal tools of diagnosis of breast disease.
Accompanying drawing explanation
Fig. 1 is a kind of structural representation of the static mammary gland dual intensity CT imaging system that the embodiment of the present invention provides；
Fig. 2 is the another kind of structural representation of the static mammary gland dual intensity CT imaging system that the embodiment of the present invention provides
Figure；
Fig. 3 is the static mammary gland dual intensity CT formation method flow chart that the embodiment of the present invention provides.
Detailed description of the invention
In order to make the purpose of the present invention, technical scheme and advantage clearer, below in conjunction with accompanying drawing and reality
Execute example, the present invention is further elaborated.Only should be appreciated that specific embodiment described herein
Only in order to explain the present invention, it is not intended to limit the present invention.
It should be noted that when element is referred to as " being fixed on " or " being arranged at " another element, and it can be straight
It is connected on another element or is connected on this another element.When an element is referred to as " being connected to " separately
One element, it can be directly to another element or be indirectly connected to this another element.
Also, it should be noted the orientation term such as left and right, upper and lower in the embodiment of the present invention, it is only mutual
For relative concept or with the normal operating condition of product as reference, and should not be regarded as restrictive
's.
Referring to accompanying drawing 1, the embodiment of the present invention provides a kind of static mammary gland dual intensity CT imaging system, including arc
Many focal spots X source device 1 of shape or fold-line-shaped, sent by many focal spots X source device 1 and worn for receiving
Cross the flat panel detector 3 of the X-ray after mammary gland 2, for carrying out high pressure and low for many focal spots X source device 1
The electric supply installation of pressure power supply, and for carrying out the processing means of image reconstruction, many focal spots X source device 1
Including at least one many focal spots X source 11, many focal spots X source 11 is provided with two or more and launches focus 111,
Many focal spots X source 11 arcuately curve tandem array is arranged so that mammary gland 2 is carried out multi-angle irradiation.Wherein,
Many focal spots X source device 1 can be independent monomer structure, it is also possible to be multiple many focal spots X sources 11
Combinative structure, its global shape is arc or fold-line-shaped so that it is can static multi-angle irradiation mammary gland 2.
Many focal spots X source device 1 is the most just arranged by flat panel detector 3, and the two has identical axis of symmetry,
Vertically divided equally by same straight line, in order to receive X-ray, and the reconstruction of beneficially image.Electric supply installation is
Many focal spots X source device 1 carries out high pressure and low-voltage power supply, to carry out dual intensity CT imaging, in order to tissue
Composition carries out qualitative analysis.Processing means prestored the darkfield image needed for image reconstruction and bright-field image and
Rebuild relational expression accordingly, to carry out CT image reconstruction according to original image.It is essential that the present embodiment
Using many focal spots X source device 1, its core cell is X-ray emission device, and the common X source of tradition is only
Having negative electrode and sun level, launch focus 111 for only 1, the X-ray emitter that the present embodiment uses is additionally arranged
Grid, i.e. includes negative electrode, anode and is arranged at grid therebetween, multiple transmitting focuses 111 connect jointly
Connecing anode, launching focus 111 position can be controlled by grid voltage, and can carry out high-low pressure and be switched fast,
And then realize dual intensity CT imaging.
The embodiment of the present invention uses many focal spots X source device 1 to substitute traditional single focus X-ray light source, and this is multifocal
Speckle X source device 1 is made up of one or more many focal spots X sources 11, and overall curved or fold-line-shaped,
Control to launch focus 111 one by one and launch X-ray, mammary gland 2 can be irradiated the most from different perspectives,
And then can be not required to rotate light supply apparatus with comprehensive static illumination mammary gland 2, and then avoid potential motion artifacts,
Improve precision and efficiency of detecting；Focal spot X source 11 more than one has multiple transmitting focus 111, is equivalent to many
Individual traditional X source, therefore can reduce the quantity of X source in a large number, and be significantly reduced to this；Many focal spots
X source 11 combines high-low pressure dual-energy imaging, has both eliminated potential motion artifacts, promotes accuracy of detection and again can
Carry out qualitative analysis, be the ideal tools of diagnosis of breast disease.
In embodiments of the present invention, the structure of many focal spots X source device 1 can have multiple, and one of which is tied
Structure is: many focal spots X source device 1 only includes many focal spots X source 11 of an arc, its multiple transmittings
Focus 111 is uniformly distributed along arc curve.Can be specifically semicircular arc, or less than semicircular arc,
Or more than semicircular arc.Another kind of structure is: many focal spots X source device 1 includes multiple radius of curvature
Many focal spots X source 11 of the arc that identical but radian is identical or different, sending out of each many focal spots X source 11
Penetrating focus 111 to be distributed along arc curve, multiple many focal spots X source 11 tandem arrays form concentric arc
Shape.The most multiple many focal spots X sources 11 form one with same point for center of circle head and the tail arrangement and have certain arc
The circular arc of degree, specifically, multiple many focal spots X sources 11 can be that radian is identical, it is also possible to is arc
Spend different, i.e. length is different, such as many focal spots X source 11 totally 3, the wherein arc in centre position
Degree maximum, the radian of two side positions is less, or centre position radian is less, and the radian of two side positions is relatively big,
Or two identical etc. arrangements of the radian of side position, the transmitting of each many focal spots X source 11
Focus 111 is uniformly distributed.Another kind of structure is as shown in Figure 2: many focal spots X source device 1 include multiple directly
Many focal spots X source 11 of line style, multiple linear many focal spots X source 11 tandem arrays form fold-line-shaped,
The transmitting focus 111 of each many focal spots X source 11 is distributed along straight uniform, and multiple many focal spots X-ray
Source 11 has same inscribed circle.It is to say, be cut in same outside linear many focal spots X source 11 is common
The arrangement continuously of one circle and head and the tail, the transmitting direction of the most whole many focal spots X source device 1 is also by each
Angle is launched to center, it is achieved static omnidirectional.
In the present embodiment, multiple transmitting focuses 111 of many focal spots X source device 1 are that time division emission X penetrates
Line, during specific works, many focal spots X source device 1 completes all to launch focus by Multiple-Scan
The transmitting of 111, in scanning process each time, several are launched focus 111 and send out the most one by one
Penetrating X-ray, in same scanning process, transmitting focus 111 position corresponding to adjacent transmission time is non-conterminous,
In adjacent scanning process, same launch time, corresponding transmitting focus 111 position was the most non-conterminous, and,
Every secondary control is launched focus 111 luminescence and is all switched under high pressure and lower pressure.Herein " during transmitting
Between " it is not necessarily referring to for natural time, but a kind of sequential concept, such as: by the in first time scanning process
The transmitting focus 111 lighted by first in the transmitting focus 111 that is lighted, and second time scanning process,
The launch time of the two transmitting focus 111 is considered identical.It is described as follows:
As a example by structure shown in Fig. 1, many focal spots X source device 1 is made up of focal spot X source 11 more than three,
Wherein, many focal spots X source 11 is respectively designated as according to locus: light source A, light source B, light source C,
Transmitting focus 111 is respectively designated as: focus A1, focus A2, focus A3, focus A4, focus B1,
Focus B2, focus B3, focus B4, focus B5, focus C1, focus C2, focus C3, focus C4.
Its shooting sequence is: scanning for the first time: focus A1 focus B1 focus C1, second time scanning: focus
A4 focus B4 focus C4, third time scanning: focus A2 focus B2 focus C2, sweep for the 4th time
Retouch: focus B5, the 5th scanning: focus A3 focus B3 focus C3.So complete all to launch
The transmitting operation of focus 111, and it is spaced luminescence owing to launching focus 111, decrease thermal accumlation, be beneficial to
Extend the service life of light supply apparatus.This is a kind of preferred embodiment of the present invention, and the present invention is not excluded for it
His shooting sequence.
In the present embodiment, the radian of many focal spots X source device 1 is preferably 30 °～360 °, each transmitting
The transmitting angle of focus 111 is 1 °～60 °.
The present invention further provides a kind of static mammary gland dual intensity CT formation method, the method is based on the present embodiment
The static mammary gland dual intensity CT imaging system provided is implemented, and comprises the steps:
In step S101, control non-conterminous transmitting focus 111 sequentially in time respectively at high pressure and low
X-ray is launched in pressure, receives the light energy after described X-ray passes mammary gland 2 by flat panel detector 3,
Obtain the original image that each transmitting focus 111 is corresponding under high pressure and low pressure；
In step s 102, carry out image reconstruction by processing means, particularly as follows: every width original image is entered
Row processes, it is thus achieved that correction map picture, correction map picture=log [(original image darkfield image)/(bright-field image details in a play not acted out on stage, but told through dialogues
Image)], wherein, represent subtraction, log represents that take the logarithm operation, darkfield image and bright-field image are
The data being pre-stored in processing means；Then, carry out CT reconstruction based on whole correction map pictures, obtain CT
Rebuild image.
In embodiments of the present invention, use this system to carry out CT imaging, " details in a play not acted out on stage, but told through dialogues figure need to be obtained before dispatching from the factory
Picture " and " bright-field image " of each focus, and be stored in processing means, it is used for CT projection picture
Do pretreatment, to improve CT reconstructed image quality.Specifically, the acquisition methods of darkfield image is: do not put
Put scanning object, close all light sources, gather several CT images with flat panel detector, by respective pixel ash
Degree superposition summation is average, obtains darkfield image.The acquisition methods of bright-field image is: controls one and launches Jiao
Point 111 is luminous, and not laying scanned gathers several CT images with flat panel detector, by respective pixel
Gray scale superposition summation is average, obtains the corresponding bright-field image launching focus 111, to each transmitting focus 111
Operate the bright-field image obtaining each transmitting focus 111 equally.In actual application after dispatching from the factory, root
The original image generated according to flat panel detector 3, and above-mentioned darkfield image and the height of each transmitting focus 111
Press light field picture, be modified as formula according to above-mentioned correction map, more all correction map pictures are carried out reconstruction obtain
Obtain CT and rebuild image.
Further, in order to avoid heat is concentrated, the sequence of light of above-mentioned transmitting focus 111 is preferably according to upper
State the mode described in embodiment, be not repeated.
Static mammary gland dual intensity CT imaging system based on the present invention carries out imaging, can avoid rotating X source,
Avoid potential motion artifacts, improve accuracy of detection and detection efficiency, simultaneously compared to using a large amount of independent X-ray
The mode in source, the method can be greatly decreased the use of X source, reduces cost, and by high-low pressure dual intensity
Imaging, it is possible to carry out accurate qualitative analysis, is the ideal scheme of diagnosis of breast disease.
These are only presently preferred embodiments of the present invention, not in order to limit the present invention, all the present invention's
Any amendment, equivalent or the improvement etc. made within spirit and principle, should be included in the guarantor of the present invention
Within the scope of protecting.
Claims (10)
1. a static mammary gland dual intensity CT imaging system, it is characterised in that include that arc or fold-line-shaped are many
Focal spot X source device, for receive sent and pass the X after mammary gland by described many focal spots X source device
The flat panel detector of light, for for described many focal spots X source device carry out high pressure and low-voltage power supply for Denso
Put, and for carrying out the processing means of image reconstruction；Described many focal spots X source device includes at least one
Many focal spots X source, each many focal spots X source is provided with two or more and launches focus, multiple described many focal spots X
Light source arcuately curve tandem array is arranged so that mammary gland to carry out multi-angle irradiation, described flat panel detector and institute
State many focal spots X source device just to and vertically divided equally by same straight line.
2. static mammary gland dual intensity CT imaging system as claimed in claim 1, it is characterised in that described many
The radian of focal spot X source device is 30 °～360 °, and the transmitting angle of each described transmitting focus is 1 °
～60 °.
3. static mammary gland dual intensity CT imaging system as claimed in claim 1, it is characterised in that described many
Focal spot X source device only includes many focal spots X source of an arc, and its multiple transmitting focuses are bent along arc
Line is distributed.
4. static mammary gland dual intensity CT imaging system as claimed in claim 1, it is characterised in that described many
Focal spot X source device includes that multiple radius of curvature is identical but many focal spots X-ray of arc that radian is identical or different
Source, the transmitting focus of each many focal spots X source is distributed along arc curve, multiple described many focal spots X sources
Tandem array forms concentric arc.
5. static mammary gland dual intensity CT imaging system as claimed in claim 1, it is characterised in that described many
Focal spot X source device includes multiple linear many focal spots X source, multiple described linear many focal spots X
Light source tandem array formed fold-line-shaped, the transmitting focus of each described many focal spots X source along lineal layout,
And multiple described many focal spots X source has same inscribed circle.
6. static mammary gland dual intensity CT imaging system as claimed in claim 1, it is characterised in that described many
The transmitting focus spaced set of focal spot X source.
7. static mammary gland dual intensity CT imaging system as claimed in claim 1, it is characterised in that described many
Focal spot X source includes negative electrode, anode and the grid being arranged between described negative electrode and anode, and described transmitting is burnt
Point is common connects described anode, controls the bright dark and height of described transmitting focus by controlling described grid voltage
Crush-cutting changes.
8. the static mammary gland dual intensity CT imaging system as described in any one of claim 1～7, it is characterised in that
Described many focal spots X source device completes all to launch the transmitting of focus by Multiple-Scan, scans each time
During, several are launched focus and launch X-ray the most one by one, in same scanning process, and phase
Adjacent launch time, corresponding transmitting focal position was non-conterminous, in adjacent scanning process, and same launch time
Corresponding transmitting focal position is the most non-conterminous.
9. a static mammary gland dual intensity CT formation method, it is characterised in that arbitrary based on claim 1～8
Static mammary gland dual intensity CT imaging system described in Xiang is implemented, and comprises the steps:
Control sequentially in time non-conterminous described transmitting focus respectively under high pressure and low pressure launch X penetrate
Line, receives the light energy after described X-ray passes mammary gland by described detector, obtains each transmitting focus
Original image corresponding under high pressure and low pressure；
Image reconstruction is carried out, particularly as follows: every width original image is processed, it is thus achieved that repair by processing means
Positive image, described correction map picture=log [(original image darkfield image)/(bright-field image darkfield image)], its
In, representing subtraction, log represents that operation of taking the logarithm, described darkfield image and bright-field image are for being pre-stored in
Data in described processing means；Then, carry out CT reconstruction based on whole described correction map pictures, obtain CT
Rebuild image.
10. mammary gland dual intensity CT formation method as claimed in claim 9 static, it is characterised in that described secretly
The acquisition methods of field picture is: not laying scanned, closes all light sources, gathers many with described detector
Width CT image, average by respective pixel gray scale superposition summation, obtain described darkfield image；
The acquisition methods of described bright-field image is: controls a described transmitting focus luminous, does not place scanning thing
Body, gathers several CT images with described detector, average by respective pixel gray scale superposition summation, obtains
The corresponding bright-field image launching focus, operates acquisition each transmitting Jiao equally to each described transmitting focus
The bright-field image of point.
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| CN106491152A (en) * | 2016-10-18 | 2017-03-15 | 深圳先进技术研究院 | A kind of static CT imaging systems based on photon detector |
| CN108122723A (en) * | 2017-12-25 | 2018-06-05 | 北京纳米维景科技有限公司 | A kind of arc multifocal fixed anode grid-control radiographic source |
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