CN105920681A - Medical catheter used for remaining needle, and preparation method thereof - Google Patents
Medical catheter used for remaining needle, and preparation method thereof Download PDFInfo
- Publication number
- CN105920681A CN105920681A CN201610455480.XA CN201610455480A CN105920681A CN 105920681 A CN105920681 A CN 105920681A CN 201610455480 A CN201610455480 A CN 201610455480A CN 105920681 A CN105920681 A CN 105920681A
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- Prior art keywords
- medical catheter
- remaining needle
- district
- antioxidant
- polyolefin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/04—Macromolecular materials
- A61L29/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/04—Macromolecular materials
- A61L29/041—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention provides a medical catheter used for a remaining needle. The medical catheter is prepared from the following raw material ingredients in parts by weight: 68-85% of thermoplastic elastomer, 8-20% of polyolefin, 0.4-1% of antioxygen, 0.4-1% of lubricating agent, 0.5-2% of antibacterial agent and 4-8% of bulking agent. The invention also further provides a preparation method of the above medical catheter used for the remaining needle. The medical catheter used for the remaining needle has the advantages of high transparency, smooth and fine surface, high cleanliness, good anti-deflection performance and excellent strength and toughness performance, and is s medical catheter with good combination property. Since polyolefin and bulking agent are adopted, the product simultaneously has high elasticity and high intensity, does not adopt filler reinforcement, and has good elasticity, anti-infection performance and sterilization performance.
Description
Technical field
The invention belongs to medical material tech field, particularly relate to a kind of tie remaining needle clean, safety and stability and use
Medical catheter and preparation method thereof.
Background technology
The most widely used remaining needle medical catheter mostly utilize traditional raw material PVC to prepare and
Become, and in PVC, normally used plasticizer or stabilizer all have certain toxicity.Conduit material is from all
On determine the indwelling result of remaining needle, therefore conduit not only to have certain intensity and is prone to puncture, and also to have
Having anti-discounting performance allow conduit give a discount or restore rapidly after distortion, catheter surface is smooth simultaneously, it is impossible to form blood
Bolt, thus reduce the infection risk that bacteria planting brings, X-ray opaque function to be had guarantees that conduit is quiet
Clearly being positioned in arteries and veins, this is particularly important when there is the rare complication such as conduit rupture, and current staying
Put pin medical catheter and cannot meet these many requirements.
Summary of the invention
In consideration of it, the invention provides a kind of without any noxious substance, transparency height, good springiness, infection
Property and bactericidal property is strong, the remaining needle medical catheter of easily processing and preparation method thereof.
First aspect present invention provides a kind of remaining needle medical catheter, and its raw material includes following components: with weight
Amount percentages, thermoplastic elastomer (TPE) 68%～85%, polyolefin 8%～20%, antioxidant 0.4%～1%,
Lubricant 0.4%～1%, antibacterial 0.5～2%, bulking agent 4～8%.
Second aspect present invention provides the preparation method of above-mentioned remaining needle medical catheter, and step includes: will be each
Raw material mix, in extruder extrude, extrusion temperature be 160 DEG C of a district, 170 DEG C of 2nd district, 180 DEG C of 3rd district,
Four 190 DEG C of districts, 210 DEG C of 5th district, die temperature 160-210 DEG C, extrudate cools down through water ring, vacuum sizing
Rear closing quotation.
The invention has the beneficial effects as follows: the remaining needle medical catheter that the present invention provides uses the thermoplastic elastomehc that knot is clean
Gonosome is prepared from, and has high transparent, and surface is moist, and cleanliness factor is higher, anti-in the wrong around functional,
Strength and toughness performance highlights, and is the medical catheter of a kind of high comprehensive performance.And whole formula system does not contains
Any noxious substance, do not add any filler thus ensure that high knot cleanliness and the safety and stability of medical catheter
Property, remain the features such as good, the easy processing of medical catheter transparency simultaneously, use polyolefin and bulking agent to make product
Have high resiliency and high intensity simultaneously concurrently, and do not use filler reinforcement, have extraordinary elasticity, anti-infection property and
Bactericidal property.
Detailed description of the invention
First aspect present invention provides remaining needle medical catheter, and its raw material includes following components: with weight hundred
Proportion by subtraction meter, thermoplastic elastomer (TPE) 68%～85%, polyolefin 8%～20%, antioxidant 0.4%～1%, profit
Lubrication prescription 0.4%～1%, antibacterial 0.5～2%, bulking agent 4～8%.
Material based on thermoplastic elastomer (TPE), it is provided that the toughness of material；Polyolefin provides material as resin
Intensity, plays enhancing modified effect to material of main part thermoplastic elastomer (TPE)；Bulking agent plays interconnection function, makes thermoplastic
Property elastomer and polyolefin be combined together to form stable co-mixing system, preferably ensure toughness and intensity；Anti-
Microbial inoculum prevents medical catheter by germ contamination；Antioxidant plays antioxidation, prevents resin when high temperature is extruded
Aging affect mechanical performance；Lubricant plays reduction moment of torsion effect, improves speed of production.Master in the technical program
Body material is thermoplastic elastomer (TPE), and weight ratio is maximum.Polyolefin is reinforced modifier, and addition selects main body material
The 15～about 20% of material, weight is smaller can not play potentiation, and weight ratio crosses conference affects the tough of material
Property.Antioxidant, lubricant and antibacterial belong to additive, and weight is the most less, and about about 1%.Increase-volume
Agent weight ratio is typically chosen about the 50% of polyethylene weight, and such proportioning can take into account the intensity of material very well
And toughness.
Preferably, described thermoplastic elastomer (TPE) include styrenic thermoplastic elastomer, TPO,
One or more in polyurethane termoplastic elastomer.
Preferably, described polyolefin includes polyethylene, polypropylene, polyamide, ethylene-octene copolymer elastomer
In one or more.
Preferably, described bulking agent includes the one in PE-g-MAH, POE-g-MAH or PA-g-MAH.
Thermoplastic elastomer (TPE), polyolefin and bulking agent specifically chosen, the most each component combine formed uniform
Co-mixing system, it is ensured that it is right that the selection of the high transparent of conduit and ultra-high purity, special polyolefins and bulking agent makes
The thermoplastic elastomer product answered has high resiliency and high intensity concurrently simultaneously, and without using filler reinforcement.
Preferably, during described antioxidant includes antioxidant 1010, anti-oxidant DLTP, antioxidant 4010
Plant or several.
Preferably, one or more in described lubricant Medical silicone oil, silicone powder, Tissuemat E.
Second aspect present invention provides the preparation method of remaining needle medical catheter, and step includes: by each raw material
Mixing, in extruder extrude, extrusion temperature be 160 DEG C of a district, 170 DEG C of 2nd district, 180 DEG C of 3rd district, four
190 DEG C of district, 210 DEG C of 5th district, die temperature 160-210 DEG C, extrudate is after water ring cooling, vacuum sizing
Closing quotation.
Specific process conditions is conducive to each component to be fully combined together to form stable co-mixing system, it is ensured that material
High transparent, high resiliency, toughness and anti-infection property and bactericidal property
Give below in conjunction with remaining needle medical catheter that the present invention is provided by specific embodiment and preparation method thereof
To further illustrate.The embodiments described below is exemplary, is only used for explaining the present invention, and is not understood that
For limitation of the present invention.
Experimental technique in following embodiment, if no special instructions, is conventional method.Institute in following embodiment
Experiment material if no special instructions, be market and be commercially available.
Embodiment 1
Present embodiments provide a kind of remaining needle medical catheter, by following raw material according to percentage by weight mixing
Become: the thermoplastic elastomer (TPE) of 75%；15% polyolefin；1% antioxidant；1% lubricant；0.5% antibacterial,
7.5% bulking agent.
Wherein, described thermoplastic elastomer (TPE) is polyurethane termoplastic elastomer；
Described polyolefin is ethylene-octene copolymer elastomer；
Described antioxidant is antioxidant 1010；
Described lubricant is Medical silicone oil；
Described bulking agent is bulking agent POE-g-MAH.
Above-mentioned remaining needle medical catheter is prepared by the following method, and step includes:
Each material above-mentioned is mixed in an extruder, extruder temperature be set as a district, 2nd district, 3rd district, four
District, 5th district are respectively 160 DEG C, 170 DEG C, 180 DEG C, 190 DEG C, 210 DEG C, and die temperature is set as
160～210 DEG C.Extrudate is closed after water ring cooling, vacuum sizing.
Gained remaining needle medical catheter transparency is good, cleanliness factor is high, has high resiliency and high intensity, infection concurrently
Property and bactericidal property are good, and are easily worked, and quality safety is stable.
Embodiment 2
Present embodiments provide a kind of remaining needle medical catheter, by following raw material according to percentage by weight mixing
Become: the thermoplastic elastomer (TPE) of 75%；15% polyolefin；1% antioxidant；1% lubricant；0.5% antibacterial,
7.5% bulking agent.
Wherein, described thermoplastic elastomer (TPE) is polyurethane termoplastic elastomer；
Described polyolefin is linear low density polyethylene；
Described antioxidant is antioxidant 1010；
Described lubricant is Medical silicone oil；
Described bulking agent is bulking agent PE-g-MAH.
Above-mentioned remaining needle medical catheter is prepared by the following method, and step includes:
Each material above-mentioned is mixed in an extruder, extruder temperature be set as a district, 2nd district, 3rd district, four
District, 5th district are respectively 160 DEG C, 170 DEG C, 180 DEG C, 190 DEG C, 210 DEG C, and die temperature is set as
160～210 DEG C.Extrudate is closed after water ring cooling, vacuum sizing.
Gained remaining needle medical catheter transparency is good, cleanliness factor is high, has high resiliency and high intensity, infection concurrently
Property and bactericidal property are good, and are easily worked, and quality safety is stable.
Embodiment 3
Present embodiments provide a kind of remaining needle medical catheter, by following raw material according to percentage by weight mixing
Become: the thermoplastic elastomer (TPE) of 80%；10% polyolefin；1% antioxidant；1% lubricant；0.5% antibacterial,
7.5% bulking agent.
Wherein, described thermoplastic elastomer (TPE) is styrenic thermoplastic elastomer；
Described polyolefin is ethylene-octene copolymer elastomer；
Described antioxidant is antioxidant 1010；
Described lubricant is silicone powder；
Described bulking agent is bulking agent POE-g-MAH.
Above-mentioned remaining needle medical catheter is prepared by the following method, and step includes:
Each material above-mentioned is mixed in an extruder, extruder temperature be set as a district, 2nd district, 3rd district, four
District, 5th district are respectively 160 DEG C, 170 DEG C, 180 DEG C, 190 DEG C, 210 DEG C, and die temperature is set as
160～210 DEG C.Extrudate is closed after water ring cooling, vacuum sizing.
Gained remaining needle medical catheter transparency is good, cleanliness factor is high, has high resiliency and high intensity, infection concurrently
Property and bactericidal property are good, and are easily worked, and quality safety is stable.
Embodiment 4
Present embodiments provide a kind of remaining needle medical catheter, by following raw material according to percentage by weight mixing
Become: the thermoplastic elastomer (TPE) of 80%；10% polyolefin；1% antioxidant；1% lubricant；0.5% antibacterial,
7.5% bulking agent.
Wherein, described thermoplastic elastomer (TPE) is styrenic thermoplastic elastomer；
Described polyolefin is linear low density polyethylene；
Described antioxidant is antioxidant 1010；
Described lubricant is silicone powder；
Described bulking agent is bulking agent PE-g-MAH.
Above-mentioned remaining needle medical catheter is prepared by the following method, and step includes:
Each material above-mentioned is mixed in an extruder, extruder temperature be set as a district, 2nd district, 3rd district, four
District, 5th district are respectively 160 DEG C, 170 DEG C, 180 DEG C, 190 DEG C, 210 DEG C, and die temperature is set as
160～210 DEG C.Extrudate is closed after water ring cooling, vacuum sizing.
Gained remaining needle medical catheter transparency is good, cleanliness factor is high, has high resiliency and high intensity, infection concurrently
Property and bactericidal property are good, and are easily worked, and quality safety is stable.
Embodiment 5
Present embodiments provide a kind of remaining needle medical catheter, by following raw material according to percentage by weight mixing
Become: the thermoplastic elastomer (TPE) of 68%；20% polyolefin；1% antioxidant；1% lubricant；2% antibacterial, 8%
Bulking agent.
Wherein, described thermoplastic elastomer (TPE) is styrenic thermoplastic elastomer and TPO, and
Two kinds of thermoplastic elastic body mass ratios are 1:1；
Described polyolefin is polypropylene and polyamide, and the mass ratio of polypropylene and polyamide is 1:2；
Described antioxidant is anti-oxidant DLTP；
Described lubricant is Tissuemat E；
Described bulking agent is bulking agent PE-g-MAH.
Above-mentioned remaining needle medical catheter is prepared by the following method, and step includes:
Each material above-mentioned is mixed in an extruder, extruder temperature be set as a district, 2nd district, 3rd district, four
District, 5th district are respectively 160 DEG C, 170 DEG C, 180 DEG C, 190 DEG C, 210 DEG C, and die temperature is set as
160～210 DEG C.Extrudate is closed after water ring cooling, vacuum sizing.
Gained remaining needle medical catheter transparency is good, cleanliness factor is high, has high resiliency and high intensity, infection concurrently
Property and bactericidal property are good, and are easily worked, and quality safety is stable.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all essences in the present invention
Within god and principle, any modification, equivalent substitution and improvement etc. made, should be included in the protection of the present invention
Within the scope of.
Claims (7)
1. a remaining needle medical catheter, it is characterised in that: its raw material includes following components: with weight hundred
Proportion by subtraction meter, thermoplastic elastomer (TPE) 68%～85%, polyolefin 8%～20%, antioxidant 0.4%～1%, profit
Lubrication prescription 0.4%～1%, antibacterial 0.5～2%, bulking agent 4～8%.
2. remaining needle medical catheter as claimed in claim 1, it is characterised in that: described thermoplastic elastic
Body includes in styrenic thermoplastic elastomer, TPO, polyurethane termoplastic elastomer
Plant or several.
3. remaining needle medical catheter as claimed in claim 1, it is characterised in that: described polyolefin includes
One or more in polyethylene, polypropylene, polyamide, ethylene-octene copolymer elastomer.
4. remaining needle medical catheter as claimed in claim 1, it is characterised in that: described antioxidant includes
One or more in antioxidant 1010, anti-oxidant DLTP, antioxidant 4010.
5. remaining needle medical catheter as claimed in claim 1, it is characterised in that: described lubricant is medical
One or more in silicone oil, silicone powder, Tissuemat E.
6. remaining needle medical catheter as claimed in claim 1, it is characterised in that: described bulking agent includes
One in PE-g-MAH, POE-g-MAH or PA-g-MAH.
7. the preparation method of the remaining needle medical catheter as described in claim 1 to 6 any one claim,
It is characterized in that: step includes: each raw material is mixed, in extruder extrude, extrusion temperature be 160 DEG C of a district,
Two 170 DEG C of districts, 180 DEG C of 3rd district, 190 DEG C of 4th district, 210 DEG C of 5th district, die temperature 160-210 DEG C, extrusion
Thing is closed after water ring cooling, vacuum sizing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610455480.XA CN105920681A (en) | 2016-06-21 | 2016-06-21 | Medical catheter used for remaining needle, and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610455480.XA CN105920681A (en) | 2016-06-21 | 2016-06-21 | Medical catheter used for remaining needle, and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105920681A true CN105920681A (en) | 2016-09-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610455480.XA Pending CN105920681A (en) | 2016-06-21 | 2016-06-21 | Medical catheter used for remaining needle, and preparation method thereof |
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| Country | Link |
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| CN (1) | CN105920681A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109568676A (en) * | 2018-12-29 | 2019-04-05 | 张桂玲 | A kind of antibacterial super slippery medical retention conduit material |
| CN110315733A (en) * | 2019-07-11 | 2019-10-11 | 河南驼人医疗器械集团有限公司 | Retaining needle flexible tube, hose extrusion system and hose extrusion process |
| CN112402777A (en) * | 2020-11-20 | 2021-02-26 | 中国人民解放军总医院第一医学中心 | Efficient styptic propeller |
| CN114316405A (en) * | 2021-12-30 | 2022-04-12 | 上海翊科聚合物科技有限公司 | Medical tube and preparation method thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109568676A (en) * | 2018-12-29 | 2019-04-05 | 张桂玲 | A kind of antibacterial super slippery medical retention conduit material |
| CN110315733A (en) * | 2019-07-11 | 2019-10-11 | 河南驼人医疗器械集团有限公司 | Retaining needle flexible tube, hose extrusion system and hose extrusion process |
| CN112402777A (en) * | 2020-11-20 | 2021-02-26 | 中国人民解放军总医院第一医学中心 | Efficient styptic propeller |
| CN112402777B (en) * | 2020-11-20 | 2022-11-04 | 中国人民解放军总医院第一医学中心 | Efficient styptic propeller |
| CN114316405A (en) * | 2021-12-30 | 2022-04-12 | 上海翊科聚合物科技有限公司 | Medical tube and preparation method thereof |
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Application publication date: 20160907 |
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