CN105920173A - Traditional Chinese medicinal composition for treating chicken infectious bronchitis - Google Patents
Traditional Chinese medicinal composition for treating chicken infectious bronchitis Download PDFInfo
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- CN105920173A CN105920173A CN201610271206.7A CN201610271206A CN105920173A CN 105920173 A CN105920173 A CN 105920173A CN 201610271206 A CN201610271206 A CN 201610271206A CN 105920173 A CN105920173 A CN 105920173A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/346—Platycodon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
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Abstract
The invention relates to a traditional Chinese medicinal composition for treating chicken infectious bronchitis. The traditional Chinese medicinal composition is prepared from the following traditional Chinese medicinal materials in parts by weight: 14-18 parts of herba houttuyniae, 10-15 parts of radix platycodi, 10-15 parts of dried tangerine or orange peel, 5-10 parts of poria cocos, and 3-5 parts of licorice root. The traditional Chinese medicinal composition has good efficacies of clearing away the lung-heat and relieving asthma, as well as relieving cough and eliminating phlegm, and can obviously improve the clinical symptoms of infectious bronchitis of the laying hen, so that the death rate is reduced, and the laying rate is recovered.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for treating infectious bronchitis of chicken, belong to technical field of traditional Chinese medicines.
Background technology
Infectious bronchitis of chicken is a kind of acute, higher the exhaling of infectiousness caused by avian infectious bronchitis virus
Desorption system disease.Clinical manifestation for cough, sneeze, the minimizing of kidney damage, egg production, degradation under Egg Quality.Avian infectious
Bronchitis virus has that speed of mutation is fast, serotype is complicated, the feature that Disease Clinical comparison in difference is big.This disease can infect appoints
The when chicken of phase, causes delayed growth, loses weight and dead, cause the Secondary cases such as Mycoplasma mixed infection and colibacillosis
Infect, increase chicken group's death quantity, bring serious loss to plant.At present infectious bronchitis of chicken be there is no effectively
Methods for the treatment of, main use epidemic prevention means to protect chicken group, but owing to this serum virus type is more, clinical vaccine exempted from
Having failure during epidemic disease, cause chicken mass-sending disease, for clinical onset, chicken group currently mainly uses symptomatic treatment, and traditional Chinese medicine is mainly powder
Powder, preparation process is simple, and product controllability is poor, bad during Clinical practice effect fashion.Infectious bronchitis of chicken mainly divides
For breathing pattern and kidney type, but preinfection is mainly breathing pattern, along with the prolongation of the course of disease, is developing progressively kidney type etc..Cause
This, the treatment beforehand control for infectious bronchitis of chicken is the most crucial.
Summary of the invention
It is an object of the invention to: for the defect of prior art, it is proposed that one is used for treating avian infectious bronchus
Scorching Chinese medicine composition, this Chinese medicine composition has good clearing lung, relieving asthma, and effect of cough-relieving apophlegmatic can be obviously improved laying hen
The clinical symptoms of infective bronchitis, reduce the death rate, recover laying rate.
The technical solution adopted in the present invention is: a kind of Chinese medicine composition for treating infectious bronchitis of chicken, by
The bulk drug composition of following parts by weight: cordate houttuynia 14~18 parts, balloonflower root 10~15 parts, dried orange peel 10~15 parts, Poria cocos 5~10
Part, Radix Glycyrrhizae 3~5 parts.
In the present invention: a kind of Chinese medicine composition for treating infectious bronchitis of chicken, by following parts by weight
Bulk drug forms: cordate houttuynia 16 parts, balloonflower root 13 parts, dried orange peel 12 parts, 8 parts of Poria cocos, 4 parts of Radix Glycyrrhizae.
In the present invention: by cordate houttuynia, balloonflower root, dried orange peel, Poria cocos and liquorice 5 taste Chinese medicine boiling, every 1ml is made containing former
The oral liquid of raw medicinal herbs 0.8~1.2g.
Above-mentioned Chinese medicine composition is possible not only to make oral liquid, it is also possible to make pulvis, capsule, tablet and particle
Agent.The cordate houttuynia property of medicine in above-mentioned Chinese medicine composition is pungent cold, pungent with dissipating bind, the heat-clearing of cold energy, and master enters lung channel, and merit is apt to removing summer-heat lung heat,
The carbuncle that disappears apocenosis, cures mainly lung heat and coughs and breathe heavily, therefore be monarch drug in a prescription;Balloonflower root opening lung-energy, dispelling phlegm and relieving sore-throat;Dried orange peel is regulated the flow of vital energy wide chest, preventing phlegm from forming and stopping coughing;Help
Monarch drug in a prescription lung heat clearing away, sputum eliminating, for ministerial drug;Poria cocos invigorating the spleen excreting dampness, wet dispelling and spleen is prosperous, phlegm is had no way of life, for adjutant;Radix Glycyrrhizae coordinating the drug actions of a prescription, holding concurrently can
Moistening lung and in;All medicines share, and play clearing lung, relieving asthma altogether, the merit of cough-relieving apophlegmatic.
After using technique scheme, the invention have the benefit that this Chinese medicine composition has good clearing lung, relieving asthma, only
Cough the effect eliminated the phlegm, the clinical symptoms of laying hen infective bronchitis can be obviously improved, reduce the death rate, recover laying rate.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment 1
A kind of Chinese medicine composition for treating infectious bronchitis of chicken, by formula composition weight ratio weigh cordate houttuynia 280g,
Above-mentioned 5 taste Chinese medicine boilings can be made 1000ml and are administered orally by balloonflower root 200g, dried orange peel 200g, Poria cocos 100g, Radix Glycyrrhizae 60g
Liquid, wherein the oral liquid of every 1ml is containing primary crude drug 0.8~1.2g.
Embodiment 2
A kind of Chinese medicine composition for treating infectious bronchitis of chicken, by formula composition weight ratio weigh cordate houttuynia 360g,
Above-mentioned 5 taste Chinese medicine boilings can be made 1000ml and are administered orally by balloonflower root 300g, dried orange peel 300g, Poria cocos 200g, Radix Glycyrrhizae 100g
Liquid, wherein the oral liquid of every 1ml is containing primary crude drug 0.8~1.2g.
Embodiment 3
A kind of Chinese medicine composition for treating infectious bronchitis of chicken, by formula composition weight ratio weigh cordate houttuynia 320g,
Above-mentioned 5 taste Chinese medicine boilings can be made 1000ml and are administered orally by balloonflower root 260g, dried orange peel 240g, Poria cocos 160g, Radix Glycyrrhizae 80g
Liquid, wherein the oral liquid of every 1ml is containing primary crude drug 0.8~1.2g.
Embodiment 4
A kind of Chinese medicine composition for treating infectious bronchitis of chicken, by formula composition weight ratio weigh cordate houttuynia 300g,
Above-mentioned 5 taste Chinese medicine boilings can be made 1000ml and are administered orally by balloonflower root 220g, dried orange peel 220g, Poria cocos 120g, Radix Glycyrrhizae 80g
Liquid, wherein the oral liquid of every 1ml is containing primary crude drug 0.8~1.2g.
Laboratory effect of drugs is investigated
By small white mouse 40, it is randomly divided into one, two groups, positive drug (ammonium chloride) control group and saline control group, often group
10, male and female half and half.One, two groups of oral liquids giving mouse gavaging 5.0ml/kg respectively, positive drug control group gives 15mg/
The ammonium chloride of kg, each group all uses normal saline dilution to become 0.4ml gavage, every day 1 time, successive administration 5 days.It is little that last is administered 1
Shi Hou, lumbar injection 0.5% phenol red solution 20ml/kg, put to death mouse in 30 minutes, peel off tracheae surrounding tissue, cut from first shape soft
Bone, down to one section of tracheae of tracheae bifurcation, is put in the test tube filling 2ml physiological saline, is added 2.24mmol/L
NaHCO3Solution 0.1ml, centrifugal 30 minutes, takes supernatant 2.24mmol/L NaHCO3Solution is settled to 5ml, uses UV, visible light
Spectrophotometer is at 546nm, with 5% NaHCO3Solution is blank, measures absorbance (A).By phenol red calibration curve
Calculate phenol red content in cleaning fluid.Result of the test is shown in Table.
Each phenol red secretory volume of experimental mice tracheae (± s, n=10)
Group | Phenol red concentration μ g/ml |
Saline control group | 0.58±0.26A |
Embodiment one group | 1.15±0.37B |
Embodiment two groups | 1.16±0.35B |
Note: capitalization difference represents that difference is extremely notable (P 0.01)
The above results is indicated, the medicine of the present invention can significantly improve phenol red secretory volume, has good expectorant effect, with physiology
The poor heteropole of saline control group is notable (P < 0.01).
Clinical effectiveness is investigated
Experimental animal: the blue brown laying hen group in 241 age in days seas, 5207 plumages.Significantly having difficulty in breathing and snore occurs in chicken group, serious
Neck, mouth breathing are stretched in sick chicken performance;Chicken group's laying rate by 87.4% original continuous decrease to 73.2%, first 7 days of statistical experiment, chicken
Group's general mortality rate is 5.2%, and the chicken that will die of illness is cutd open inspection and finds, indivedual chicken bronchials have slight bleeding point, and tracheal strips has white sputum.
Hen house and utensil are cleaned and sterilizes, ill chicken group is randomly divided into a treatment group (350 by chicken coop numbering
Plumage), two treatment groups (350 plumage), chicken house conventional therapy group (350 plumage) and positive controls (100 plumage).One, two therapeutic component are other
By 0.5ml/kg body weight drinking water administration;Chicken house conventional therapy group uses Maxingshigan oral liquid drinking water administration, successive administration 5 days.
Positive controls does not give any medicine.Result of the test see table.
Each death condition organizing test chicken
Note: lowercase difference represents significant difference (P 0.05), and lowercase identical table differential is different the most notable.
The above results illustrates, the medicine of the present invention can well improve infectious bronchitis of chicken clinical symptoms, less
The death rate, recovers laying rate, and effect is better than chicken house conventional therapy group.Notable (P < 0.05) with positive controls comparing difference.
Above the detailed description of the invention of the present invention is described, but the present invention is not limited to above description.For this
For the technical staff in field, any equal amendment to the technical program and replacement are all within the scope of the invention.Cause
This, the impartial conversion made without departing from the spirit and scope of the invention and amendment, all should contain in the scope of the present invention.
Claims (2)
1. one kind for treating the Chinese medicine composition of infectious bronchitis of chicken, it is characterised in that: former by following parts by weight
Material medicine composition: cordate houttuynia 14~18 parts, balloonflower root 10~15 parts, dried orange peel 10~15 parts, Poria cocos 5~10 parts, Radix Glycyrrhizae 3~5 parts.
A kind of Chinese medicine composition for treating infectious bronchitis of chicken the most according to claim 1, it is characterised in that:
It is made up of the bulk drug of following parts by weight: cordate houttuynia 16 parts, balloonflower root 13 parts, dried orange peel 12 parts, 8 parts of Poria cocos, 4 parts of Radix Glycyrrhizae.
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CN201610271206.7A CN105920173A (en) | 2016-04-28 | 2016-04-28 | Traditional Chinese medicinal composition for treating chicken infectious bronchitis |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111840404A (en) * | 2020-09-07 | 2020-10-30 | 安徽省正大源饲料集团有限公司 | Traditional Chinese medicine additive for improving poultry resistance and preparation method thereof |
CN114886987A (en) * | 2021-06-26 | 2022-08-12 | 临沂金翠兽药有限公司 | Composition for relieving poultry bronchitis and preparation method and use method thereof |
CN116808108A (en) * | 2022-03-22 | 2023-09-29 | 河北天元药业有限公司 | Antiviral traditional Chinese medicine composition containing houttuynia cordata and application thereof |
CN116808107A (en) * | 2022-03-22 | 2023-09-29 | 河北天元药业有限公司 | Preparation process of traditional Chinese medicine compound preparation containing houttuynia cordata |
Citations (4)
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CN101439175A (en) * | 2008-12-25 | 2009-05-27 | 杭州万得富生物技术有限公司 | Chinese medicine preparation for treating nephropathogenic infectious bronchitis in chicken |
CN101940646A (en) * | 2010-09-07 | 2011-01-12 | 陈鹏举 | Chinese medicine composition for preventing and curing nephropathogenic infectious bronchitis |
CN102357154A (en) * | 2011-11-01 | 2012-02-22 | 天津生机集团股份有限公司 | Traditional Chinese medicine composition for preventing and treating avian infectious bronchitis and preparation method thereof |
CN104666882A (en) * | 2015-03-30 | 2015-06-03 | 曲斌斌 | Traditional Chinese medicine granules for treating chronic bronchitis and preparation method of traditional Chinese medicine granules |
-
2016
- 2016-04-28 CN CN201610271206.7A patent/CN105920173A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101439175A (en) * | 2008-12-25 | 2009-05-27 | 杭州万得富生物技术有限公司 | Chinese medicine preparation for treating nephropathogenic infectious bronchitis in chicken |
CN101940646A (en) * | 2010-09-07 | 2011-01-12 | 陈鹏举 | Chinese medicine composition for preventing and curing nephropathogenic infectious bronchitis |
CN102357154A (en) * | 2011-11-01 | 2012-02-22 | 天津生机集团股份有限公司 | Traditional Chinese medicine composition for preventing and treating avian infectious bronchitis and preparation method thereof |
CN104666882A (en) * | 2015-03-30 | 2015-06-03 | 曲斌斌 | Traditional Chinese medicine granules for treating chronic bronchitis and preparation method of traditional Chinese medicine granules |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111840404A (en) * | 2020-09-07 | 2020-10-30 | 安徽省正大源饲料集团有限公司 | Traditional Chinese medicine additive for improving poultry resistance and preparation method thereof |
CN114886987A (en) * | 2021-06-26 | 2022-08-12 | 临沂金翠兽药有限公司 | Composition for relieving poultry bronchitis and preparation method and use method thereof |
CN116808108A (en) * | 2022-03-22 | 2023-09-29 | 河北天元药业有限公司 | Antiviral traditional Chinese medicine composition containing houttuynia cordata and application thereof |
CN116808107A (en) * | 2022-03-22 | 2023-09-29 | 河北天元药业有限公司 | Preparation process of traditional Chinese medicine compound preparation containing houttuynia cordata |
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Address after: 221200 A District, South Ring Road Industrial Park, Suining County, Xuzhou, Jiangsu. Applicant after: Xuzhou Providence animal pharmaceutical industry Limited by Share Ltd Address before: 221200 A District, South Ring Road Industrial Park, Suining County, Xuzhou, Jiangsu. Applicant before: XUZHOU TIANYI ANIMAL PHARMACEUTICAL CO., LTD. |
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Application publication date: 20160907 |
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