CN105876390A - Dried orange peel functional salt with oxidation resistance - Google Patents

Dried orange peel functional salt with oxidation resistance Download PDF

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Publication number
CN105876390A
CN105876390A CN201410468205.2A CN201410468205A CN105876390A CN 105876390 A CN105876390 A CN 105876390A CN 201410468205 A CN201410468205 A CN 201410468205A CN 105876390 A CN105876390 A CN 105876390A
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CN
China
Prior art keywords
salt
orange peel
dried orange
free radical
pericarpium citri
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CN201410468205.2A
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Chinese (zh)
Inventor
高天成
唐娜
王学魁
周莹
杨亚茹
张蕾
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Tianjin University of Science and Technology
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Tianjin University of Science and Technology
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Priority to CN201410468205.2A priority Critical patent/CN105876390A/en
Publication of CN105876390A publication Critical patent/CN105876390A/en
Pending legal-status Critical Current

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  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a dried orange peel functional salt with oxidation resistance. The dried orange peel functional salt is prepared mainly from dried orange peel as an active ingredient and a sea salt as a carrier. The raw materials comprise 5.0-50.0% of dried orange peel and 50-95% of a sea salt. The edible dried orange peel functional salt with a certain granularity and color is prepared from the above raw materials through dissolution, extraction, mixing, evaporation crystallization and drying. The dried orange peel functional salt has oxidation resistance, can effectively inhibit free radical-caused human oxidation damage, has important treatment and prevention effects on a plurality of common and frequently-occurring diseases such as hypertension, diabetes and atherosclerosis, can effectively prevent aging, memory deterioration, dysgnosia and muscle atrophy and is an important role in cancer prevention.

Description

A kind of Pericarpium Citri Reticulatae function salt with non-oxidizability
Technical field
The present invention relates to the medicated diet technical field of health food, traditional Chinese medical science integration of edible and medicinal herbs, especially a kind of with Pericarpium Citri Reticulatae effective ingredient (class Flavone) it is the Pericarpium Citri Reticulatae salt that human body is had anti-oxidation function of major function raw material development.
Background technology
Human lesion and aging are had a significant impact by the oxidation of free radical, the theory of nearly 50 years and it is experimentally confirmed that free radical theory is One of the most convictive causes of senescence.
Free radical theory is thought, free radical is the atom with azygous electronics or molecule, has the activity of height, in human body Material can constantly produce free radical in metabolic process.Appropriate free radical is that necessary to human life activity, it not only may be used To promote cell proliferation, it is also possible to stimulate leukocyte and phagocyte to kill antibacterial, diminish inflammation, decompose poisonous substance.Free radical Kind a lot, wherein with O-2Most with OH isoreactivity oxygen-derived free radicals quantity, account for more than the 95% of interior free yl.Its Middle OH is almost the intermediate material of whole oxidation reaction, the intermediate material that can react with the macromole at any position, It is the most active, is also most to have abrasive free radical simultaneously.
Human free radical results from two aspects: one is high temperature in environment, radiation, photodissociation, chemical substance etc., causes covalency The exogenous free radical that the homolysis of key produces;Two is the endogenous free radical that various metabolic responses produce in human body, and endogenous is freely Base is the main source of human free radical.Free radical has strong oxidizing property, can be with intracellular biomolecule such as protein, DNA Etc. reacting, thus cause cell ageing.
Oxidative metabolism in organism can produce a small amount of free radical, and free radical is the material that a class has high activity, Ke Yi Continuously producing in cellular process, it can play strong oxidation directly or indirectly, participates in the life of body widely Reason and pathological process.The result that the oxidation reaction of free radical and induction thereof is poisoned for a long time, can cause aging and the death of body.One In the case of as, internal antioxidant system can remove to maintain the metabolic balance of free radical in time, but at some impairment factors Effect lower can the accumulation of a large amount of free radicals in inductor, in cell during anti-oxidation protection mechanism deficiency, make active oxygen produce and pile up also Cell is produced toxicity, thus produces the unbalanced state of oxidative and anti-oxidative.
The maximum infringement that body is caused by reactive oxygen free radical is to make lipid peroxidation, and lipid peroxidation is to lipoid in biomembrane Structural damage is very big, and on biomembrane after unsaturated fatty acid peroxidating, double-decker destroys, and film function is impaired, causes organelle Dysfunction.Meanwhile, the material that lipid peroxidation produces can cause series reaction, makes cell generation degeneration, necrosis, causes The generation of the old and feeble and multiple disease of whole body.
Free radical also can produce direct Oxidative demage effect to nucleic acid and protein, and protein synthesis minimizing is senile memory Power goes down, one of the major reason of dysnoesia and amyotrophy etc..About the research of free radical with old and feeble relation, have with Lower viewpoint: " oxygen-derived free radicals is old and feeble determiner, plays vital effect in senescence process.Therefore, if reducing Free radical generates and enhancing body antiradical activities, effectively maintenance dynamic equilibrium therebetween, must have slow down aging, Sanatory effect.”
Cancer is that a class serious threat human body is healthy and the commonly encountered diseases of life security and frequently-occurring disease.Free radical be many enzymes, Active intermediate in chemistry and biology reaction;And in chemistry and the biomacromolecule that causes of radiation and body injury process In exist in a large number, make the shaping and development close ties of it and cancer.Carcinogenic is a variety of because have, have physics, chemistry, Biological etc..Some factor is worked by free radical, especially preinvasive cancer, and the effect of free radical is more by weight Depending on.Chemical carcinogen, is structurally diversified, but its common feature is in vivo after metabolism, becomes active The ultimate carcinogens of form, they are probably electrophilic reagent, it is easy to and nucleophilic group combination, or it is transformed into radical form, draw Play genetic change.Radiation in physics carcinogenic factor and ultraviolet carcinogenesis, then mainly because of ray water excited or Ionization, the hydrone homolysis exciting and ionizing produces free radical (H and OH), causes nucleic acid and Protein Damage, change Gene regulation and carcinogenic.As can be seen here, free radical all plays important role in any carcinogenic factor, gives protection against cancer in advance Disease largely can from remove free radical set about, from root or during contain the pathological changes of cell and the generation of cancer, fall The sickness rate of low all kinds of cancer.
Summary of the invention
It is an object of the invention to the Pericarpium Citri Reticulatae salt that human body is had anti-oxidation function being main function raw material development with Pericarpium Citri Reticulatae, this Non-oxidizability effect can effectively suppress the Oxidative demage effect of radical pair human body, to hypertension, diabetes, Atherosclerosis Changes etc. are multiple common and frequently-occurring disease has important treatment and prevention effect, simultaneously can also effective pre-anti-aging, hypomnesis, intelligence Power obstacle and amyotrophy etc., and in terms of prophylaxis of cancer sickness rate, play important role.
A kind of Pericarpium Citri Reticulatae function salt with non-oxidizability of the present invention, main raw material(s) is made up of Pericarpium Citri Reticulatae and sea salt, with sea salt as carrier Being aided with Pericarpium Citri Reticulatae effective ingredient, the proportioning of raw material is 5.0%-50.0%, and the optimum proportioning selected by research is 10.0%-20.0%.
By above raw material according to the ratio selected, through dissolving, extract, mixing, evaporative crystallization, the technique such as dry is made has Certain particle size and the edible Pericarpium Citri Reticulatae function salt of color and luster.
Salt is chlorine and the main source of sodium element in human body, material indispensable in the metabolism of human body.Salt is as the most normal Flavoring agent, it also has great effect as adjuvant or prescription.Compendium of Material Medica has a cloud: " salt is the master of all kinds of diseases and ailments, All kinds of diseases and ailments use it invariably.Therefore the kidney invigorating pharmaceutical salts soup person, salty Gui Shendan, it is dirty also that medicine gas enters this.Reinforcing the heart medicinal stir-fry salt person, heart hardship is empty, With salty benefit also.Spleen reinforcing medicinal stir-fry salt person, reinforcing the mother-organ for treating deficiency of the son-organ, spleen be the son of the heart also.Control the person of accumulation tuberculosis use, salty energy softening the hard mass Also." and sea salt not only contains sodium chloride, the trace element wanted possibly together with many needed by human body, compared with other edible salt, doctor More considerable by curative effect.
Pericarpium Citri Reticulatae, gas is fragrant, warm in nature, return lung, spleen channel, has effect of regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm, and be exactly the traditional Chinese medical science can not from ancient times Or the medical material simply lacked.Shennong's Herbal is said: " the inverse gas of Pericarpium Citri Reticulatae master abdominal mass in the heart heat, diuretic paddy, clothes are deodorized for a long time, and the therapeutic method to keep the adverse QI flowing downwards is led to God." in Pericarpium Citri Reticulatae containing multiple types flavonoid substance, as a big class physiologically active ingredient of Pericarpium Citri Reticulatae, flavonoid has diversified Biological activity and pharmacological action, have important controlling to the multiple commonly encountered diseases such as hypertension, diabetes, atherosclerosis and frequently-occurring disease Treat or preventive effect.
Flavonoid substances has significant antioxidation, is referred to as " free radical street cleaner ".By flavonoid to free-radical oxidation The inhibitory action of property, has certain retarding action for cell ageing and collective's aging.Pericarpium Citri Reticulatae effective ingredient flavonoid and sea salt In conjunction with, there is the biggest medical curative effect as human body antioxidation.
Pericarpium Citri Reticulatae flavonoid is effective antioxidation, the composition of defying age in Pericarpium Citri Reticulatae.Containing substantial amounts of flavonoid substances in Pericarpium Citri Reticulatae, its Middle great majority have obvious non-oxidizability, flavone that wherein content is relatively low and the oxidation resistance of flavonol and remove free radical Ability is the strongest
In Pericarpium Citri Reticulatae, flavonoid can reach antioxidation by scavenging activated oxygen thus plays effect of anticancer defying age, and can pass through Reduce blood glucose, reduce blood fat, reduce glucose in urine and treat hypertension, diabetes and complication thereof, also can the siberian crabapple of enhancing body System function and play hepatoprotective effect.
By technology controlling and process, the Pericarpium Citri Reticulatae function salt particle obtained is fine and smooth, and color and luster is good, and as a kind of Chinese medicine health-care salt, does not but have There is the niff of Chinese medicine, have the delicate fragrance of one fruit on the contrary, the most suitable as edible salt.Its except the saline taste of salt and one Almost without Pericarpium Citri Reticulatae delicate fragrance beyond, not some other affect the strange taste of mouthfeel, can eat as daily completely Salt is used for cooking.
Detailed description of the invention
A kind of Pericarpium Citri Reticulatae function salt with non-oxidizability, is prepared from through following processing step by the raw material of following weight ratio: wherein Pericarpium Citri Reticulatae 5.0%-50.0%, sea salt 50%-95%.
1. Pericarpium Citri Reticulatae pulverizer is pulverized, sift out, with sieve, the Dried Tangerine Peel that granularity is 50 mesh;
2. raw material is weighed according to above-mentioned proportion: Dried Tangerine Peel and sea salt;
3. the ethanol of Dried Tangerine Peel and 70% is mixed according to solid-to-liquid ratio 1: 30, distill at a temperature of 60 DEG C, obtain extracting solution;
4. extracting solution obtains concentrated solution through filtering, evaporating, standby;
5. sea salt is dissolved in distilled water and obtains saturated solution, and through being filtrated to get filtrate, standby;
6. concentrated solution and filtrate that 4., 5. step obtains are mixed, by evaporative crystallization, obtain salt slurry;
The most above-mentioned salt slurry i.e. obtains finished product salt through operations such as dry, packagings.
The Pericarpium Citri Reticulatae function salt that the present invention obtains has specific granularity and color and luster, on the premise of having non-oxidizability function, also has There is good mouthfeel, be suitable for all groups daily edible.
Embodiment 1
Taking Dried Tangerine Peel and the sea salt of constant weight, wherein Pericarpium Citri Reticulatae accounts for 10%, and sea salt accounts for 90%, Dried Tangerine Peel and 70% ethanol is pressed Mix according to solid-to-liquid ratio 1: 30, distill at a temperature of 60 DEG C, the liquid after dissolving by the extracting solution obtained and sea salt Mix, at a certain temperature, be evaporated crystallization, obtain salt slurry, the operation such as drying, packaging, obtain finished product Salt.After measured, the Flavonoid Content of this salt is 0.30-0.35mg/g, with DPPH free radical scavenging method and assay NBT photoreduction Product salt is carried out antioxidation detection, represents that antioxidant activity, half suppression ratio (IC50) refer to clearly with half suppression ratio (IC50) Concentration except antioxidant required when rate is 50%.After testing, reaching half suppression ratio (IC50), DPPH free radical scavenging method needs The concentration of salt solution wanted is 14.50-15.00mg/ml, and the concentration of salt solution that assay NBT photoreduction needs is 13.00-13.50mg/ml。
Embodiment 2
Taking Dried Tangerine Peel and the sea salt of constant weight, wherein Pericarpium Citri Reticulatae accounts for 20%, and sea salt accounts for 80%, Dried Tangerine Peel and 70% ethanol is pressed Mix according to solid-to-liquid ratio 1: 30, distill at a temperature of 60 DEG C, the liquid after dissolving by the extracting solution obtained and sea salt Mix, at a certain temperature, be evaporated crystallization, obtain salt slurry, the operation such as drying, packaging, obtain finished product Salt.After measured, the Flavonoid Content of this salt is 0.40-0.45mg/g, with DPPH free radical scavenging method and assay NBT photoreduction Product salt carrying out antioxidation detection, after testing, reaches half suppression ratio (IC50), the salt that DPPH free radical scavenging method needs is molten Liquid concentration is 11.00-11.50mg/ml, and the concentration of salt solution that assay NBT photoreduction needs is 12.00-12.50mg/ml.

Claims (2)

1. having a Pericarpium Citri Reticulatae function salt for non-oxidizability, main raw material(s) is made up of Pericarpium Citri Reticulatae and sea salt, it is characterized in that with sea salt as carrier Being aided with Pericarpium Citri Reticulatae effective ingredient, the proportioning of described Pericarpium Citri Reticulatae function salt is 5.0%-50.0%.
A kind of Pericarpium Citri Reticulatae function salt with non-oxidizability the most according to claim 1, it is characterised in that most preferably joining of Pericarpium Citri Reticulatae function salt Ratio is defined as 10.0%-20.0%.
CN201410468205.2A 2014-09-12 2014-09-12 Dried orange peel functional salt with oxidation resistance Pending CN105876390A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106616849A (en) * 2016-12-29 2017-05-10 天津保元堂生物科技有限公司 Sweet potato medicinal food salt and preparation method thereof
CN106616850A (en) * 2016-12-29 2017-05-10 天津保元堂生物科技有限公司 Pericarpium citri reticulatae medicated food salt and preparation method thereof
CN106880026A (en) * 2017-04-25 2017-06-23 四川理工学院 A kind of root of kudzu vine Baoshang edible salt and preparation method thereof
CN108968011A (en) * 2018-08-18 2018-12-11 安徽国科生物科技有限公司 A kind of three high crowds small-molecular peptides mushroom salt and preparation method thereof
CN109090562A (en) * 2018-08-18 2018-12-28 安徽国科生物科技有限公司 A kind of low sodium high energy mushroom salt and preparation method thereof
CN109105861A (en) * 2018-08-18 2019-01-01 安徽国科生物科技有限公司 A kind of four high sea cucumber peptide salt and preparation method thereof of prevention and treatment

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1141739A (en) * 1996-02-09 1997-02-05 陈觉非 Health-care salt
KR20040054451A (en) * 2002-12-18 2004-06-25 최규원 Customized Health Salt Manufacturing Method
CN101502325A (en) * 2009-03-12 2009-08-12 陈觉非 Health-care salt
CN103549365A (en) * 2013-10-23 2014-02-05 中盐安徽盐化集团股份有限公司 Method for preparing edible salt added with bamboo ingredients

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1141739A (en) * 1996-02-09 1997-02-05 陈觉非 Health-care salt
KR20040054451A (en) * 2002-12-18 2004-06-25 최규원 Customized Health Salt Manufacturing Method
CN101502325A (en) * 2009-03-12 2009-08-12 陈觉非 Health-care salt
CN103549365A (en) * 2013-10-23 2014-02-05 中盐安徽盐化集团股份有限公司 Method for preparing edible salt added with bamboo ingredients

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106616849A (en) * 2016-12-29 2017-05-10 天津保元堂生物科技有限公司 Sweet potato medicinal food salt and preparation method thereof
CN106616850A (en) * 2016-12-29 2017-05-10 天津保元堂生物科技有限公司 Pericarpium citri reticulatae medicated food salt and preparation method thereof
CN106880026A (en) * 2017-04-25 2017-06-23 四川理工学院 A kind of root of kudzu vine Baoshang edible salt and preparation method thereof
CN108968011A (en) * 2018-08-18 2018-12-11 安徽国科生物科技有限公司 A kind of three high crowds small-molecular peptides mushroom salt and preparation method thereof
CN109090562A (en) * 2018-08-18 2018-12-28 安徽国科生物科技有限公司 A kind of low sodium high energy mushroom salt and preparation method thereof
CN109105861A (en) * 2018-08-18 2019-01-01 安徽国科生物科技有限公司 A kind of four high sea cucumber peptide salt and preparation method thereof of prevention and treatment

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