CN105859293B - Vitreous carbon and its manufactured artificial trachea for artificial trachea - Google Patents

Vitreous carbon and its manufactured artificial trachea for artificial trachea Download PDF

Info

Publication number
CN105859293B
CN105859293B CN201610312354.9A CN201610312354A CN105859293B CN 105859293 B CN105859293 B CN 105859293B CN 201610312354 A CN201610312354 A CN 201610312354A CN 105859293 B CN105859293 B CN 105859293B
Authority
CN
China
Prior art keywords
parts
vitreous carbon
artificial trachea
polyacrylonitrile
titanium dioxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201610312354.9A
Other languages
Chinese (zh)
Other versions
CN105859293A (en
Inventor
不公告发明人
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bengbu Zhicong Information Technology Co.,Ltd.
Original Assignee
叶青
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 叶青 filed Critical 叶青
Priority to CN201610312354.9A priority Critical patent/CN105859293B/en
Publication of CN105859293A publication Critical patent/CN105859293A/en
Application granted granted Critical
Publication of CN105859293B publication Critical patent/CN105859293B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/08—Carbon ; Graphite
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/515—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxide ceramics
    • C04B35/52—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxide ceramics based on carbon, e.g. graphite
    • C04B35/524—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxide ceramics based on carbon, e.g. graphite obtained from polymer precursors, e.g. glass-like carbon material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/10—Ceramics or glasses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2002/046—Tracheae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/22—Materials or treatment for tissue regeneration for reconstruction of hollow organs, e.g. bladder, esophagus, urether, uterus
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2235/00—Aspects relating to ceramic starting mixtures or sintered ceramic products
    • C04B2235/02—Composition of constituents of the starting material or of secondary phases of the final product
    • C04B2235/30—Constituents and secondary phases not being of a fibrous nature
    • C04B2235/32—Metal oxides, mixed metal oxides, or oxide-forming salts thereof, e.g. carbonates, nitrates, (oxy)hydroxides, chlorides
    • C04B2235/3201—Alkali metal oxides or oxide-forming salts thereof
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2235/00—Aspects relating to ceramic starting mixtures or sintered ceramic products
    • C04B2235/02—Composition of constituents of the starting material or of secondary phases of the final product
    • C04B2235/30—Constituents and secondary phases not being of a fibrous nature
    • C04B2235/32—Metal oxides, mixed metal oxides, or oxide-forming salts thereof, e.g. carbonates, nitrates, (oxy)hydroxides, chlorides
    • C04B2235/3205—Alkaline earth oxides or oxide forming salts thereof, e.g. beryllium oxide
    • C04B2235/3208—Calcium oxide or oxide-forming salts thereof, e.g. lime
    • C04B2235/3212—Calcium phosphates, e.g. hydroxyapatite
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2235/00—Aspects relating to ceramic starting mixtures or sintered ceramic products
    • C04B2235/02—Composition of constituents of the starting material or of secondary phases of the final product
    • C04B2235/30—Constituents and secondary phases not being of a fibrous nature
    • C04B2235/32—Metal oxides, mixed metal oxides, or oxide-forming salts thereof, e.g. carbonates, nitrates, (oxy)hydroxides, chlorides
    • C04B2235/3231—Refractory metal oxides, their mixed metal oxides, or oxide-forming salts thereof
    • C04B2235/3232—Titanium oxides or titanates, e.g. rutile or anatase
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2235/00—Aspects relating to ceramic starting mixtures or sintered ceramic products
    • C04B2235/02—Composition of constituents of the starting material or of secondary phases of the final product
    • C04B2235/30—Constituents and secondary phases not being of a fibrous nature
    • C04B2235/48—Organic compounds becoming part of a ceramic after heat treatment, e.g. carbonising phenol resins
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2235/00—Aspects relating to ceramic starting mixtures or sintered ceramic products
    • C04B2235/02—Composition of constituents of the starting material or of secondary phases of the final product
    • C04B2235/50—Constituents or additives of the starting mixture chosen for their shape or used because of their shape or their physical appearance
    • C04B2235/54—Particle size related information
    • C04B2235/5418—Particle size related information expressed by the size of the particles or aggregates thereof
    • C04B2235/5427—Particle size related information expressed by the size of the particles or aggregates thereof millimeter or submillimeter sized, i.e. larger than 0,1 mm
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2235/00—Aspects relating to ceramic starting mixtures or sintered ceramic products
    • C04B2235/02—Composition of constituents of the starting material or of secondary phases of the final product
    • C04B2235/50—Constituents or additives of the starting mixture chosen for their shape or used because of their shape or their physical appearance
    • C04B2235/54—Particle size related information
    • C04B2235/5418—Particle size related information expressed by the size of the particles or aggregates thereof
    • C04B2235/5436—Particle size related information expressed by the size of the particles or aggregates thereof micrometer sized, i.e. from 1 to 100 micron
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2235/00—Aspects relating to ceramic starting mixtures or sintered ceramic products
    • C04B2235/70—Aspects relating to sintered or melt-casted ceramic products
    • C04B2235/96—Properties of ceramic products, e.g. mechanical properties such as strength, toughness, wear resistance

Abstract

The invention discloses a kind of vitreous carbon for artificial trachea and its manufactured artificial tracheas, and the raw material based on following parts by weight is included by the vitreous carbon of artificial trachea：40 ~ 100 parts of polyacrylonitrile, 30 ~ 40 parts of polysiloxanes, 80 ~ 100 parts of cellulose acetate, 20 ~ 30 parts of polyvinyl chloride, 10 ~ 20 parts of tricalcium phosphate, 90 ~ 100 parts of potassium oxide, 20 ~ 70 parts of titanium dioxide, 60 ~ 90 parts of dimethyl silicone polymer.Preparation method：Polyacrylonitrile, polysiloxanes, cellulose acetate, polyvinyl chloride, tricalcium phosphate, potassium oxide, titanium dioxide, dimethyl silicone polymer are uniformly mixed, and are melted, and are cooled and shaped；Carbonization treatment is carried out in no oxygen medium, then heats to 2000 ~ 3000 DEG C of 1 ~ 2h of reaction.The vitreous carbon biological stability of the present invention is preferable, and elasticity modulus is 22 ~ 24GPa, and fatigue strength is 93 ~ 100MPa, and compression strength is 680 ~ 700MPa, and resistance to biodeterioration can be strong.

Description

Vitreous carbon and its manufactured artificial trachea for artificial trachea
Technical field
The present invention relates to biological medicine Material Field more particularly to a kind of vitreous carbons and its preparation side for artificial trachea Method.
Background technology
Vitreous carbon (GC) is a kind of novel carbon material vitreous carbons, have air-tightness and good conductivity, coefficient of thermal expansion it is small, Quality is hard and is easily polished into minute surface, chemical inertness, has the characteristics that higher hydrogen overpotential, therefore suitable for doing electrochemistry With the working electrode material of electroanalysis.Vitreous carbon is referred to as due to its port pattern glass similar with structure feature, is 1962 Year has almost been invented simultaneously by the Davison and Japan Yamada of Britain.Since vitreous carbon has, density is small, high temperature resistant, anti- The characteristics such as infiltration, make it have been widely used in numerous areas such as chemical industry, metallurgical industry, electronics industry, bioengineering.
Vitreous carbon is with air-tightness and good conductivity, coefficient of thermal expansion are small, quality is hard and it is lazy to be easily polished into minute surface, chemistry Property, there is higher hydrogen overpotential, therefore suitable for doing electrochemistry and the working electrode material of electroanalysis.Electrode Form has rodlike, disk, rotating circular disk, rotating ring disk electrode (r.r.d.e) etc..The potential range that glassy carbon electrode is applicable in is wider, both can be Inorganic matter is studied in negative potential area, can also study the redox reaction of the organic matter mostly occurred in positive potential area.Make base with it Body can also prepare mercury membrane glass-carbon electrode and chemically modified electrode.Electrode to carry out before use surface polishing, chemical treatment and Electrochemical treatments.
Invention content
In view of the deficiencies of the prior art, the present invention provides a kind of for vitreous carbon of artificial trachea and preparation method thereof, glass Glass carbon resistance to biodeterioration can be strong.
In order to solve the above-mentioned technical problem, the present invention uses following technical scheme：
For the vitreous carbon of artificial trachea, include the raw material of following parts by weight meter：40~100 parts of polyacrylonitrile, poly- silica 30~40 parts of alkane, 80~100 parts of cellulose acetate, 20~30 parts of polyvinyl chloride, 10~20 parts of tricalcium phosphate, potassium oxide 90~ 100 parts, 20~70 parts of titanium dioxide, 60~90 parts of dimethyl silicone polymer.
As a further refinement of the present invention, for the vitreous carbon of artificial trachea, include the raw material of following parts by weight meter： 70 parts of polyacrylonitrile, 35 parts of polysiloxanes, 90 parts of cellulose acetate, 25 parts of polyvinyl chloride, 15 parts of tricalcium phosphate, potassium oxide 95 Part, 50 parts of titanium dioxide, 70 parts of dimethyl silicone polymer.
As a further refinement of the present invention, the grain size of titanium dioxide is 40~150 μm.
As a further refinement of the present invention, the molecular weight of polyacrylonitrile is 10000~20000.
The present invention also provides a kind of preparation methods of the vitreous carbon for artificial trachea.
A kind of preparation method of vitreous carbon for artificial trachea, includes the following steps：Polyacrylonitrile, polysiloxanes, vinegar Acid cellulose, polyvinyl chloride, tricalcium phosphate, potassium oxide, titanium dioxide, dimethyl silicone polymer are uniformly mixed, and fusing is cooled to Type；Carbonization treatment is carried out in no oxygen medium, then heats to 2000~3000 DEG C of 1~2h of reaction, the carbonization treatment time is 20 ~50min.
A kind of artificial trachea uses above-mentioned vitreous carbon to be made.
Advantageous effect：The vitreous carbon of the prior art causes wherein metal ion to surrounding tissue due to bioenvironmental corrosion Diffusion, vitreous carbon of the invention can be used as artificial trachea application, and not perishable diffusion is the glass because after carbonization treatment Carbon biological stability is preferable, and elasticity modulus is 22~24GPa, and fatigue strength is 93~100MPa, compression strength for 680~ 700MPa, resistance to biodeterioration can be strong.
Specific embodiment
With reference to specific embodiment, the invention will be further described.
Embodiment 1
For the vitreous carbon of artificial trachea, include the raw material of following parts by weight meter：70 parts of polyacrylonitrile, polysiloxanes 35 Part, 90 parts of cellulose acetate, 25 parts of polyvinyl chloride, 15 parts of tricalcium phosphate, 95 parts of potassium oxide, 50 parts of titanium dioxide, poly dimethyl 70 parts of siloxanes.
The grain size of titanium dioxide is 100 μm.
The molecular weight of polyacrylonitrile is 15000.
A kind of preparation method of vitreous carbon for artificial trachea, includes the following steps：Polyacrylonitrile, polysiloxanes, vinegar Acid cellulose, polyvinyl chloride, tricalcium phosphate, potassium oxide, titanium dioxide, dimethyl silicone polymer are uniformly mixed, and fusing is cooled to Type；Carbonization treatment is carried out in no oxygen medium, then heats to 2500 DEG C of reaction 1.5h.
The carbonization treatment time is 40min.
Embodiment 2
For the vitreous carbon of artificial trachea, include the raw material of following parts by weight meter：40 parts of polyacrylonitrile, polysiloxanes 30 Part, 80 parts of cellulose acetate, 20 parts of polyvinyl chloride, 10 parts of tricalcium phosphate, 90 parts of potassium oxide, 20 parts of titanium dioxide, poly dimethyl 60 parts of siloxanes.
The grain size of titanium dioxide is 40 μm.
The molecular weight of polyacrylonitrile is 10000.
A kind of preparation method of vitreous carbon for artificial trachea, includes the following steps：Polyacrylonitrile, polysiloxanes, vinegar Acid cellulose, polyvinyl chloride, tricalcium phosphate, potassium oxide, titanium dioxide, dimethyl silicone polymer are uniformly mixed, and fusing is cooled to Type；Carbonization treatment is carried out in no oxygen medium, then heats to 2000 DEG C of reaction 1h.
The carbonization treatment time is 20min.
Embodiment 3
For the vitreous carbon of artificial trachea, include the raw material of following parts by weight meter：100 parts of polyacrylonitrile, polysiloxanes 40 Part, 100 parts of cellulose acetate, 30 parts of polyvinyl chloride, 20 parts of tricalcium phosphate, 100 parts of potassium oxide, 70 parts of titanium dioxide, poly- diformazan 90 parts of radical siloxane.
The grain size of titanium dioxide is 150 μm.
The molecular weight of polyacrylonitrile is 20000.
A kind of preparation method of vitreous carbon for artificial trachea, includes the following steps：Polyacrylonitrile, polysiloxanes, vinegar Acid cellulose, polyvinyl chloride, tricalcium phosphate, potassium oxide, titanium dioxide, dimethyl silicone polymer are uniformly mixed, and fusing is cooled to Type；Carbonization treatment is carried out in no oxygen medium, then heats to 3000 DEG C of reaction 2h.
The carbonization treatment time is 50min.
Embodiment 4
For the vitreous carbon of artificial trachea, include the raw material of following parts by weight meter：90 parts of polyacrylonitrile, polysiloxanes 33 Part, 85 parts of cellulose acetate, 22 parts of polyvinyl chloride, 12 parts of tricalcium phosphate, 93 parts of potassium oxide, 30 parts of titanium dioxide, poly dimethyl 70 parts of siloxanes.
The grain size of titanium dioxide is 60 μm.
The molecular weight of polyacrylonitrile is 12000.
A kind of preparation method of vitreous carbon for artificial trachea, includes the following steps：Polyacrylonitrile, polysiloxanes, vinegar Acid cellulose, polyvinyl chloride, tricalcium phosphate, potassium oxide, titanium dioxide, dimethyl silicone polymer are uniformly mixed, and fusing is cooled to Type；Carbonization treatment is carried out in no oxygen medium, then heats to 2200 DEG C of reaction 1.2h.
The carbonization treatment time is 25min.
Embodiment 5
For the vitreous carbon of artificial trachea, include the raw material of following parts by weight meter：80 parts of polyacrylonitrile, polysiloxanes 38 Part, 97 parts of cellulose acetate, 28 parts of polyvinyl chloride, 18 parts of tricalcium phosphate, 98 parts of potassium oxide, 60 parts of titanium dioxide, poly dimethyl 80 parts of siloxanes.
The grain size of titanium dioxide is 130 μm.
The molecular weight of polyacrylonitrile is 18000.
A kind of preparation method of vitreous carbon for artificial trachea, includes the following steps：Polyacrylonitrile, polysiloxanes, vinegar Acid cellulose, polyvinyl chloride, tricalcium phosphate, potassium oxide, titanium dioxide, dimethyl silicone polymer are uniformly mixed, and fusing is cooled to Type；Carbonization treatment is carried out in no oxygen medium, then heats to 2800 DEG C of reaction 1.8h.
The carbonization treatment time is 40min.
Comparative example 1
Same as Example 1, difference is：The step of carrying out carbonization treatment is omitted in no oxygen medium.
Performance test
The properties of product of embodiment and comparative example are measured, the results are shown in Table 1.
Table 1
Conclusion：Vitreous carbon biological stability after carbonization treatment is preferable, will not be as the vitreous carbon of the prior art is due to life The corrosion of substance environment causes wherein metal ion to be spread to surrounding tissue, and vitreous carbon elasticity modulus of the invention is 22~24GPa, Fatigue strength is 93~100MPa, and compression strength is 680~700MPa, and resistance to biodeterioration can be strong.

Claims (1)

1. a kind of artificial trachea, uses vitreous carbon to be made；It is characterized in that, the vitreous carbon includes the original of following parts by weight meter Material：40~100 parts of polyacrylonitrile, 30~40 parts of polysiloxanes, 80~100 parts of cellulose acetate, 20~30 parts of polyvinyl chloride, phosphorus Sour 10~20 parts of tricalcium, 90~100 parts of potassium oxide, 20~70 parts of titanium dioxide, 60~90 parts of dimethyl silicone polymer；
The grain size of titanium dioxide is 40~150 μm；The molecular weight of polyacrylonitrile is 10000~20000.
CN201610312354.9A 2014-11-10 2014-11-10 Vitreous carbon and its manufactured artificial trachea for artificial trachea Active CN105859293B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610312354.9A CN105859293B (en) 2014-11-10 2014-11-10 Vitreous carbon and its manufactured artificial trachea for artificial trachea

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201410625934.4A CN104445142B (en) 2014-11-10 2014-11-10 Vitreous carbon for artificial trachea and preparation method thereof
CN201610312354.9A CN105859293B (en) 2014-11-10 2014-11-10 Vitreous carbon and its manufactured artificial trachea for artificial trachea

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201410625934.4A Division CN104445142B (en) 2014-11-10 2014-11-10 Vitreous carbon for artificial trachea and preparation method thereof

Publications (2)

Publication Number Publication Date
CN105859293A CN105859293A (en) 2016-08-17
CN105859293B true CN105859293B (en) 2018-06-29

Family

ID=52892006

Family Applications (7)

Application Number Title Priority Date Filing Date
CN201610312249.5A Active CN105948750B (en) 2014-11-10 2014-11-10 Vitreous carbon and its manufactured artificial trachea
CN201610312354.9A Active CN105859293B (en) 2014-11-10 2014-11-10 Vitreous carbon and its manufactured artificial trachea for artificial trachea
CN201610310549.XA Expired - Fee Related CN105948749B (en) 2014-11-10 2014-11-10 The preparation method of the strong vitreous carbon of resistance to biodeterioration energy, artificial trachea
CN201610310581.8A Active CN106039397B (en) 2014-11-10 2014-11-10 The preparation method of vitreous carbon, artificial trachea
CN201610310548.5A Active CN106007719B (en) 2014-11-10 2014-11-10 A kind of preparation method of the strong vitreous carbon of resistance to biodeterioration energy, artificial trachea
CN201410625934.4A Active CN104445142B (en) 2014-11-10 2014-11-10 Vitreous carbon for artificial trachea and preparation method thereof
CN201610312351.5A Expired - Fee Related CN105999395B (en) 2014-11-10 2014-11-10 A kind of preparation method of vitreous carbon, artificial trachea

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN201610312249.5A Active CN105948750B (en) 2014-11-10 2014-11-10 Vitreous carbon and its manufactured artificial trachea

Family Applications After (5)

Application Number Title Priority Date Filing Date
CN201610310549.XA Expired - Fee Related CN105948749B (en) 2014-11-10 2014-11-10 The preparation method of the strong vitreous carbon of resistance to biodeterioration energy, artificial trachea
CN201610310581.8A Active CN106039397B (en) 2014-11-10 2014-11-10 The preparation method of vitreous carbon, artificial trachea
CN201610310548.5A Active CN106007719B (en) 2014-11-10 2014-11-10 A kind of preparation method of the strong vitreous carbon of resistance to biodeterioration energy, artificial trachea
CN201410625934.4A Active CN104445142B (en) 2014-11-10 2014-11-10 Vitreous carbon for artificial trachea and preparation method thereof
CN201610312351.5A Expired - Fee Related CN105999395B (en) 2014-11-10 2014-11-10 A kind of preparation method of vitreous carbon, artificial trachea

Country Status (1)

Country Link
CN (7) CN105948750B (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3505187B2 (en) * 1996-08-28 2004-03-08 日清紡績株式会社 Glassy carbon and method for producing the same
AU2006336412A1 (en) * 2005-05-03 2007-08-02 Nanocomp Technologies, Inc. Nanotube composite materials and methods of manufacturing same
CN102276280A (en) * 2011-04-20 2011-12-14 上海交通大学 Vitreous carbon and carbon additive based composite thin plate and preparation method thereof
CN102936763A (en) * 2012-10-12 2013-02-20 福建师范大学 Glass carbon nanometer fiber preparation method
CN103508437A (en) * 2013-08-13 2014-01-15 南京工业大学 Preparation method of phenolic resin base glass carbon microsphere

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3548649B2 (en) * 1996-03-26 2004-07-28 東海カーボン株式会社 Carbon heating element
JP2005326240A (en) * 2004-05-13 2005-11-24 Toshiba Corp Analyzing container and method for analyzing very small amount of element
CN102448880B (en) * 2009-05-26 2015-04-01 创业发展联盟技术有限公司 Carbon material and method for producing the same
WO2011014258A2 (en) * 2009-07-31 2011-02-03 Massachusetts Institute Of Technology Systems and methods related to the formation of carbon-based nanostructures
CN101626075B (en) * 2009-08-03 2011-03-30 北京化工大学 Stannum and carbon composite nano-fiber film negative-electrode material and preparation method thereof
CN102168324B (en) * 2011-03-08 2012-08-22 西安工程大学 Carbonization device for electrostatically spinning nanometer tows and preparation method of carbon nanofibers

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3505187B2 (en) * 1996-08-28 2004-03-08 日清紡績株式会社 Glassy carbon and method for producing the same
AU2006336412A1 (en) * 2005-05-03 2007-08-02 Nanocomp Technologies, Inc. Nanotube composite materials and methods of manufacturing same
CN102276280A (en) * 2011-04-20 2011-12-14 上海交通大学 Vitreous carbon and carbon additive based composite thin plate and preparation method thereof
CN102936763A (en) * 2012-10-12 2013-02-20 福建师范大学 Glass carbon nanometer fiber preparation method
CN103508437A (en) * 2013-08-13 2014-01-15 南京工业大学 Preparation method of phenolic resin base glass carbon microsphere

Also Published As

Publication number Publication date
CN106007719B (en) 2018-06-29
CN104445142B (en) 2016-11-23
CN105859293A (en) 2016-08-17
CN105948750B (en) 2018-08-10
CN105948750A (en) 2016-09-21
CN106007719A (en) 2016-10-12
CN105948749B (en) 2018-06-29
CN105999395B (en) 2019-01-01
CN104445142A (en) 2015-03-25
CN106039397B (en) 2019-05-17
CN106039397A (en) 2016-10-26
CN105948749A (en) 2016-09-21
CN105999395A (en) 2016-10-12

Similar Documents

Publication Publication Date Title
CN105523541B (en) Porous carbon tiny balloon of Heteroatom doping and preparation method thereof
Habibi et al. A carbon nanotube modified electrode for determination of caffeine by differential pulse voltammetry
KR101826585B1 (en) Nitrogen-doped graphene aggregate and method of preparing the same
CN107449816B (en) All solid state ion selective electrode, preparation method and biosensor
Li et al. A catechol biosensor based on electrospun carbon nanofibers
CN103794803A (en) Preparation method and application of nitrogen and phosphorus codoped carbon oxygen reduction catalyst for microbial fuel cell
Tsujimura et al. CueO-immobilized porous carbon electrode exhibiting improved performance of electrochemical reduction of dioxygen to water
CN110527973B (en) Method for preparing boron-doped diamond by using solid-state doping source
CN107012535A (en) A kind of method for preparing graphene/glass composite fibre
CN108455571A (en) A kind of micropore graphene aerogel and preparation method thereof
CN105859293B (en) Vitreous carbon and its manufactured artificial trachea for artificial trachea
CN105800589B (en) A kind of vitreous carbon and its manufactured artificial trachea
Pandian et al. Metal‐free Sulfur‐doped graphitic carbon nitride‐modified GCE‐based electrocatalyst for the enhanced electrochemical determination of Omeprazole in Drug formulations and Biological Samples
CN105399086B (en) A kind of method that sodium chloride auxiliary prepares graphene perforated membrane
Luo et al. Electrochemical behavior of ascorbic acid and rutin on poly (L-arginine)-graphene oxide modified electrode
CN105047433B (en) A kind of preparation method of super capacitor electrode
Mohanty et al. Conducting pyrolysed carbon scaffold for tissue engineering
ATE456868T1 (en) METHOD FOR PRODUCING AN ELECTROLYTIC CATALYST SUPPORT, ELECTROLYTIC CATALYST SUPPORT AND ELECTROCHEMICAL ELECTRODE
Sahoo et al. A single step solid NH4F-assisted method for the removal of hard silica template to obtain microporous carbon for electrochemical applications
CN108448164A (en) Sode cell based on self-supporting fluorine nitrogen-doped graphene film
CN109133039A (en) A kind of self assembly graphene nano film and its preparation method and application
KR20190086290A (en) Biosorbent and a method for continosuly recovering lithum using the same
da Rosa Braun et al. Influence of the 3D architecture and surface roughness of SiOC anodes on bioelectrochemical system performance: a comparative study of freeze-cast, 3D-printed, and tape-cast materials with uniform composition
Wilson et al. Variation of Carbon Based Materials on the Electropolymerization of Tyramine
TW201533937A (en) Flexible thermoelectric material film and manufacturing method thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
TA01 Transfer of patent application right

Effective date of registration: 20180611

Address after: 362100 306, room 3, Nanyuan garden, Southeast garden, 3, Lo Town, Huian, Fujian.

Applicant after: Ye Qing

Address before: 213000 Jinling North Road, Xinbei District, Changzhou, Jiangsu, China, Hohai University

Applicant before: Wu Jie

TA01 Transfer of patent application right
TR01 Transfer of patent right

Effective date of registration: 20200526

Address after: 230001 room 1201, block a, Zhongrui building, No.9, Hongfeng Road, hi tech Zone, Hefei City, Anhui Province

Patentee after: Anhui Dart Intellectual Property Service Co.,Ltd.

Address before: 362100 306, room 3, Nanyuan garden, Southeast garden, 3, Lo Town, Huian, Fujian.

Patentee before: Ye Qing

TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20200903

Address after: 233799 19th floor, investment building, Chengguan Town, Guzhen County, Bengbu City, Anhui Province

Patentee after: Bengbu Zhicong Information Technology Co.,Ltd.

Address before: 230001 room 1201, block a, Zhongrui building, No.9, Hongfeng Road, hi tech Zone, Hefei City, Anhui Province

Patentee before: Anhui Dart Intellectual Property Service Co.,Ltd.

TR01 Transfer of patent right