CN105853020A - Fine particle inhaling device for building animal injury model - Google Patents
Fine particle inhaling device for building animal injury model Download PDFInfo
- Publication number
- CN105853020A CN105853020A CN201610348563.9A CN201610348563A CN105853020A CN 105853020 A CN105853020 A CN 105853020A CN 201610348563 A CN201610348563 A CN 201610348563A CN 105853020 A CN105853020 A CN 105853020A
- Authority
- CN
- China
- Prior art keywords
- dust
- cloud
- fine particle
- injury model
- pipeline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241001465754 Metazoa Species 0.000 title claims abstract description 47
- 230000006378 damage Effects 0.000 title claims abstract description 34
- 208000027418 Wounds and injury Diseases 0.000 title claims abstract description 30
- 239000010419 fine particle Substances 0.000 title claims abstract description 30
- 208000014674 injury Diseases 0.000 title claims abstract description 28
- 239000000428 dust Substances 0.000 claims abstract description 166
- 238000011109 contamination Methods 0.000 claims abstract description 7
- 238000011084 recovery Methods 0.000 claims abstract description 7
- 239000003500 flue dust Substances 0.000 claims description 18
- 238000006243 chemical reaction Methods 0.000 claims description 10
- 239000011148 porous material Substances 0.000 claims description 6
- 235000019504 cigarettes Nutrition 0.000 claims description 3
- 238000010521 absorption reaction Methods 0.000 abstract description 4
- 230000000694 effects Effects 0.000 abstract description 4
- 239000002245 particle Substances 0.000 abstract description 4
- 238000010171 animal model Methods 0.000 abstract description 2
- 239000000779 smoke Substances 0.000 abstract 1
- 239000004509 smoke generator Substances 0.000 abstract 1
- 239000013618 particulate matter Substances 0.000 description 9
- 238000011160 research Methods 0.000 description 8
- 238000003915 air pollution Methods 0.000 description 4
- 239000008187 granular material Substances 0.000 description 4
- 230000036541 health Effects 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 230000008859 change Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000002028 premature Effects 0.000 description 3
- 238000004088 simulation Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 230000000711 cancerogenic effect Effects 0.000 description 2
- 231100000315 carcinogenic Toxicity 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 210000002345 respiratory system Anatomy 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 1
- 208000037273 Pathologic Processes Diseases 0.000 description 1
- 208000031320 Teratogenesis Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000003123 bronchiole Anatomy 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000010485 coping Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000002375 environmental carcinogen Substances 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 231100000016 inhalation toxicity Toxicity 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 231100000219 mutagenic Toxicity 0.000 description 1
- 230000003505 mutagenic effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000009054 pathological process Effects 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 231100000719 pollutant Toxicity 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 230000003519 ventilatory effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Environmental Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Biodiversity & Conservation Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Animal Husbandry (AREA)
- Wood Science & Technology (AREA)
- Public Health (AREA)
- Housing For Livestock And Birds (AREA)
Abstract
The invention belongs to the technical field of animal model building, and particularly relates to a fine particle inhaling device for building an animal injury model. The fine particle inhaling device for building the animal injury model comprises a dust smoke generator, a dust inhaling device and a dust smoke recovering device, wherein the inhaling device can form stable fine particle inhaling environment with controllable concentration so as to build the animal injury model for simulating a dust-haze environment; meanwhile, the inhaling device can achieve the goal of performing stable fine particle inhaling on various animals at the same time in one step; various particles can even be used for realizing the absorption contamination. The inhaling device has the advantages that the structure is simple; the operation is easy; the animal absorption contamination effect is more stable and more uniform; the recovering device is installed, so that the particle recovery can be realized; the secondary pollution on environment and the injury on the experiment personnel are avoided.
Description
Technical field
The invention belongs to animal model constructing technology field, be specifically related to a kind of for building animal injury
The fine particle suction apparatus of model.
Background technology
PM2.5 also referred to as can suck lung particulate matter, refers to aerodynamic in total air suspended particulates
Diameter is less than or equal to the particulate matter of 2.5 μm.Although PM2.5 is, in earth atmosphere composition, content is very
Few component, but it has important impact to environmental quality, air visibility and health etc..
There are some researches show, the particulate matter time of staying in an atmosphere is long, can fed distance remote, coverage
Greatly, the least harm to health of particle size is the biggest, this is because diameter is the least, and particulate matter
The position and the degree of depth that enter respiratory tract present negative correlation with diameter: the particulate matter of usual 10 μ m diameter is usual
It is deposited on upper respiratory tract, and the be deep into bronchioles below 2 μm and alveolar.With thicker air
Particulate matter is compared, and PM2.5 particle diameter is less, after fine particle entrance human body to alveolar, can directly affect
The ventilatory function of lung, makes body easily be in anaerobic condition, and long-term exposure can be caused cardiovascular diseases and exhale
Inhale tract disease, additionally, organic pollution and heavy metals such as PM2.5 easily absorbing multiring aromatic hydrocarbons, make cause
Cancer, teratogenesis, mutagenic probability are significantly raised, thus to health and the shadow of atmosphere quality
Ring bigger.
It is reported, when in air, the concentration of PM2.5, for a long time higher than 10, can bring about the rising of mortality risk；
Concentration often increases by 10, and total mortality risk rises 4%, and the mortality risk that heart and lung diseases brings rises 6%,
The mortality risk that pulmonary carcinoma is brought rises 8%." the global environment of United Nations Environment Programme's announcement in 2012
Prospect 5 " point out have 700,000 people to die from the respiratory system disease caused because of ozone every year, have nearly 200
The premature death case of ten thousand is relevant with Particulate Pollution." institute of NAS periodical " (PNAS) also
Having delivered research report, claimed in report, the average life of the mankind is because air pollution is likely to contract
Short 5 years half.
The report that the World Bank issues shows, outdoor air pollution the premature death number caused, flat
It is people's every day 1000, has the people of 35 to 40 ten thousand to be faced with death every year.Specifically, as far back as 1997
Year, the World Bank just in advance in respect of 50,000 Chinese because air pollution and premature death.On the whole,
The report of this part finds, the air pollution of China makes the life-span of urbanite decrease 18 years.
On October 17th, 2013, subordinate's international cancer research institution of World Health Organization (WHO) issues report,
Point out atmospheric pollution first carcinogenic to the mankind, and regard it as universal and main environmental carcinogen.Air
Polluting and be suggested as an overall carcinogenic factor, the injury of human body is probably by it contained several by it
The result that big pollutant act on simultaneously.
PM2.5 can produce multiple organ, the damage of Mutiple Targets to body, is chronic, a long-term disease
Reason change procedure, therefore in terms of research PM2.5 mechanism and coping strategy thereof, sets up at simulation PM2.5
Give chronic PM2.5 aerosol under onset environment and expose formation animal injury model, can be more real anti-
Reflecting pathological process, this also becomes an important directions of PM2.5 research.But existing structure animal damages
The fine particle suction apparatus of wound model is not all suitable for simulating the structure of PM2.5 gray haze damage model,
This mainly has a following reason: 1, existing special animal granule inhalation device is it is generally required at subnormal ambient
Under process, typically result in that its structure is complex, cost is high；2, the self-control granule of research and development
The mode of suction apparatus many employings Neulized inhalation, can cause the model humidity built too high, it is impossible to simulation
Normal PM2.5 gray haze environment, is not particularly suited for the research of PM2.5 model；And existing self-control
Grain suction apparatus is many cannot form the suction source lasting, stable, concentration is controlled, causes animal suction
Fine particle concentration unstable；And general many of home-made contrivance carries out an animal operation or many move
Thing easily squeezes a ball, and has a strong impact on the suction effect of animal；And discarded fine particle does not enter
Row reclaims, and experimenter is also damaged by easy secondary environmental pollution.Visible, the most existing
The granule suction apparatus of molding or known to the suction apparatus researched and developed the most voluntarily, for research
The structure of the animal injury model needed for the impact of PM2.5 is the most inapplicable, has also had a strong impact on PM2.5
Further investigation.
Summary of the invention
To this end, the technical problem to be solved is to provide a kind of for building animal injury mould
The fine particle suction apparatus of type, with solve suction apparatus in prior art be not suitable for build PM2.5
The problem of animal injury model under environment.
For solving above-mentioned technical problem, the fine grained for building animal injury model of the present invention
Thing suction apparatus, including the cloud of dust generator being sequentially connected with and cloud of dust inhaler；
Described cloud of dust generator includes for storing the dust storage warehouse of flue dust, scalable flue dust goes out dust quantity
Constant speed regulator part, and be connected with the described cloud of dust inhaler cloud of dust is delivered to the described cloud of dust inhale
Enter the cloud of dust generation pipeline of device.
Described cloud of dust inhaler includes the hermetic container being connected with described cloud of dust generation pipeline, described appearance
By being provided with the base plate of accommodating animal at bottom position in device, and the cloud of dust for not sucking flows out and reclaims
Cloud of dust effuser.
Described constant speed regulator part includes frequency conversion constant speed regulator and the screw rod batcher being connected, institute
State screw rod batcher and through described dust storage warehouse and stretch into described cloud of dust generation pipeline, and by described
The regulation of frequency conversion constant speed regulator realizes flue dust and at the uniform velocity flows into described cloud of dust generation pipeline.
Described dust storage warehouse is Y type funnel-shaped structure, and described screw rod batcher is through bell mouth and wears
Cross described dust storage warehouse and stretch into described cloud of dust generation pipeline, when described screw rod batcher rotates, can
Flue dust is driven at the uniform velocity to enter described cloud of dust generation pipeline from dust storage warehouse.
Described cloud of dust generation pipeline is horizontally disposed L-type pipeline configuration, and described dust storage warehouse is arranged
In the top of described cloud of dust generation pipeline two-arm junction, an arm of force pipeline of described cloud of dust generation pipeline
Stretching into described flue dust inhaler and realize cloud of dust conveying, another arm of force pipeline is away from described dust storage warehouse
The first fan is installed in side.
In described cloud of dust inhaler, described cloud of dust effuser through described base plate and hangs down mutually with described base plate
Straight setting, the top of described cloud of dust effuser and sidewall are provided with pore and flow out recovery for the cloud of dust.
The side-walls of described cloud of dust effuser is provided with some longitudinal flutings and can be inserted into baffle plate, described baffle plate with
The space of accommodating animal to be contaminated is formed between described base plate.
Described hermetic container is cylindrical structure container, and described cloud of dust generation pipeline stretches to described airtight
Container by tip portion, the end face of described hermetic container is connected with column side wall hasp lock, it is achieved
Mobilizable airtight connection.
The top of described hermetic container is provided with the second fan, with fully by cloud of dust mix homogeneously.
Described suction apparatus also includes the cloud of dust withdrawer being connected with described cloud of dust withdrawer, it is achieved not
Suck the recovery of the cloud of dust.
Described cloud of dust withdrawer includes the connecting tube being connected with described cloud of dust inhaler, described connecting tube
Being positioned at below described base plate and be connected with described cloud of dust effuser, described connecting tube stretches into returnable,
The cloud of dust not sucked by animal is recycled in described returnable.
The bag-shaped filter being installed on described connecting tube end it is provided with in described returnable.
Fine particle suction apparatus for building animal injury model of the present invention, sends out including the cloud of dust
Raw device, cloud of dust inhaler and cloud of dust withdrawer, described suction apparatus be possible not only to be formed stable,
The fine particle suction environment that concentration is controlled, to build the animal injury model under simulation gray haze environment；
Meanwhile, described suction apparatus can realize disposably many animals being carried out stable fine particle simultaneously
Suck, it might even be possible to use multiple particulate matter to realize absorbing contamination.Suction apparatus structure of the present invention
Simply, easily operated, it is more stable, uniform that animal absorbs contamination effect, and is provided with retracting device,
The recovery of particulate matter can be realized, it is to avoid secondary pollution to environment, and the injury to experimenter.
Accompanying drawing explanation
In order to make present disclosure be more likely to be clearly understood, below according to the concrete reality of the present invention
Executing example and combine accompanying drawing, the present invention is further detailed explanation, wherein,
Fig. 1 is the structural representation of suction apparatus of the present invention；
In figure, reference is expressed as: 1-frequency conversion constant speed regulator, 2-screw rod batcher, and 3-dust stores
Storehouse, 4-one-way cock, 5-cloud of dust generation pipeline, 6-the first fan, 7-the second fan, 8-hermetic container,
9-cloud of dust effuser, 10-baffle plate, 11-connecting tube, 12-returnable, 13-base plate, 14-pore, 15-
Support.
Detailed description of the invention
As it is shown in figure 1, the fine particle for building animal injury model of the present invention sucks dress
Putting, including the cloud of dust generator being sequentially connected with and cloud of dust inhaler, wherein, described cloud of dust generator is used
In forming uniform flue dust, described cloud of dust inhaler is used for contaminating the animal suction cloud of dust to build described damage
Wound model.
Described cloud of dust generator includes support 15, and is arranged on described support 15 for storing flue dust
Dust storage warehouse 3, scalable flue dust goes out the constant speed regulator part of dust quantity, and sucks with the described cloud of dust
Device is connected and the cloud of dust is delivered to the cloud of dust generation pipeline 5 of described cloud of dust inhaler.Described constant speed regulator
The dust quantity that goes out of part regulation flue dust guarantees that it is uniform, then is carried by the cloud of dust by described cloud of dust generation pipeline 5
Animal contaminated is carried out to described cloud of dust inhaler.
Described constant speed regulator part includes frequency conversion constant speed regulator 1 and the screw rod batcher 2 being connected,
Scalable frequency conversion constant speed regulator 1 adjustable rotating speed 0-60 rev/min also connects screw rod batcher 2, and screw rod is fixed
Measuring device 2 has fine thread, it is possible to through described dust storage warehouse and stretch into described cloud of dust generation pipeline,
And realize flue dust by the regulation of described frequency conversion constant speed regulator 1 and at the uniform velocity flow into described cloud of dust generation pipeline 5.
Suction apparatus as shown in Figure 1 gives the structure of a kind of dust storage warehouse, described dust storage warehouse 3
For Y type funnel-shaped structure, the described cloud of dust generation pipeline 5 that dust storage warehouse 3 is fixed on support 15
Top, is the cylindrical structural of a root length about 10cm, and above it, about 3cm is hollowed out presenting funnel
Shape structure, is lural channel design in the middle of the part of the about 7cm of lower section, described screw rod batcher
2 from the horn-like bell mouth of described dust storage warehouse 3 penetrate and by it bottom hopper channel pass, work as spiral shell
During bar batcher 2 uniform rotation, flue dust can be driven at the uniform velocity to enter the described cloud of dust from dust storage warehouse 3 and to send out
Raw pipeline 5.
Described cloud of dust generation pipeline 5 is horizontally placed on described support 15, is positioned at described dust storage warehouse
The lower section of 3, is mainly used in carrying out animal injury dye in the prepared cloud of dust is delivered to described cloud of dust inhaler
Poison.Described cloud of dust generation pipeline 5 is horizontally disposed L-type pipeline configuration, described dust storage warehouse 3
It is arranged at the top position of described cloud of dust generation pipeline 5 two-arm junction, and described screw rod batcher 2
Stretch in described cloud of dust generation pipeline 5.One arm of force pipeline of described cloud of dust generation pipeline 5 stretches into institute
State flue dust inhaler upper end, realize cloud of dust conveying as venthole, equipped with one-way cock 4 at gas outlet
In case gas flow counterflow；Another arm of force is then admission line, and stores up away from described dust at described pipeline
The first fan 6 is installed in the side of storage 3, promotes that air enters in described cloud of dust generation pipeline 5.Work as institute
State the first fan 6 open generation air-flow thus the flue dust got off will be sent to break up shape by screw rod batcher 2
Cheng Fenyan, and enter cloud of dust inhaler from other end venthole.Described cloud of dust inhaler includes with described
The hermetic container 8 that cloud of dust generation pipeline 5 is connected, described hermetic container 8 uses pmma material system
Becoming, described container is made diameter and is about 50cm, the cylindrical structure of high 60cm, this is because cylinder
Body structure relatively square structure is easier to make the cloud of dust be evenly distributed.The cylinder end face of described hermetic container 8
Can open, be connected with cylinder hasp lock, can be airtight when connecting fixing, and at described hermetic container 8
Top side the second fan 7 is installed with fully by powder cigarette mix homogeneously.
Described cloud of dust generation pipeline 5 stretches at the top position of described hermetic container 8, described container
Interior leaning on is provided with the base plate 13 for housing animal, the sidewall of described cloud of dust effuser 9 at bottom position
Place is additionally provided with several longitudinal flutings, and available baffle plate 10 inserts fixing, thus by cloud of dust effuser with
It is different to place that space between described hermetic container 8 cylinder is divided into several fan-shaped animal fixed bits
Animal.There is a connecting hole cylinder bottom surface, and connecting hole upper end is provided with set perpendicular with described base plate
The cloud of dust effuser 9 put, the diameter of described cloud of dust effuser 9 is about 10cm, high about 30cm, institute
All there are several pores 14 end face and the side of stating cloud of dust effuser 9, by described cloud of dust generation pipeline 5
Can not entered by described pore 14 by the cloud of dust of Animal Inhalation Toxicity Exposure in being delivered to described hermetic container 8
Enter described cloud of dust effuser 9, and flow out by described cloud of dust effuser 9 and be recovered.
As it is shown in figure 1, as improvable structure, fine particle absorption plant of the present invention also wraps
Include the cloud of dust withdrawer being connected with described cloud of dust withdrawer, it is achieved do not suck the recovery of the cloud of dust.Institute
State the connecting tube 11 that cloud of dust withdrawer includes being connected, described connecting tube diameter with described cloud of dust inhaler
For 10cm and be positioned at below described base plate 13 and be connected with described cloud of dust effuser 9, described connection
Pipe 11 stretches into returnable 12, is recycled to by the cloud of dust not sucked by animal in described returnable 12,
Described returnable 12 is done absorption built with water and is used, and is additionally provided with simultaneously and is installed on described connecting tube end
The bag-shaped filter of end, strengthens assimilation effect further.
Present invention fine particle suction apparatus as shown in Figure 1 carries out toy fine particle Inhalation
Process as follows:
First, open the top side hasp of the hermetic container 8 of described cloud of dust inhaler, will petty action be contaminated
Thing is positioned over the sector region being made up of base plate 13 and baffle plate 10 and fixes, the most airtight top side hasp lock,
Form a suction environment sealed；
The cloud of dust is put into dust storage warehouse 3, starts frequency conversion constant speed regulator 1, screw rod batcher 2 simultaneously
Start therewith to rotate, and drive the cloud of dust to enter L-type cloud of dust generation pipeline 5 from dust storage warehouse 3, open
The first fan 6 at L-type cloud of dust generation pipeline 5 air inlet, produces certain air-flow and the cloud of dust is broken up shape
Cheng Fenyan also enters cloud of dust inhaler from other end venthole, dense by the cloud of dust in measuring cloud of dust inhaler
Degree regulates the rotating speed of frequency conversion constant speed regulator 1, until it reaches require concentration；
The second fan 7 starting described hermetic container 8 top side fully will enter described cloud of dust inhaler
Smog mix homogeneously, cloud of dust air-flow is flowed out by the pore of pressure cloud of dust effuser 9 from cloud of dust inhaler,
Contamination animal starts to accept the cloud of dust and sucks, until it reaches seeking time；And the cloud of dust not sucked by contamination
Granule then enters in returnable 12 along connecting tube 11, a part of bag-like filter of the cloud of dust that part is discarded
Net filtration, another part is adsorbed by water, thus reduces the amount entering environment, by particulate matter in water
Reclaim, reuse after sterilizing.
Fine particle suction apparatus of the present invention, can simulate the cloud of dust completely and suck environment, moving of structure
Thing damage model is suitable for carrying out the research of PM2.5 environmental effect.
Obviously, above-described embodiment is only for clearly demonstrating example, and not to embodiment
Limit.For those of ordinary skill in the field, can also do on the basis of the above description
Go out change or the variation of other multi-form.Here without also all of embodiment being given thoroughly
Lift.And the obvious change thus extended out or variation are still in the protection model of the invention
Among enclosing.
Claims (10)
1. the fine particle suction apparatus being used for building animal injury model, it is characterised in that bag
Include the cloud of dust generator and cloud of dust inhaler being sequentially connected with；
Described cloud of dust generator includes for storing the dust storage warehouse (3) of flue dust, scalable flue dust goes out
The constant speed regulator part of dust quantity, and be connected with the described cloud of dust inhaler cloud of dust is delivered to described dirt
Cloud of dust generation pipeline (5) of cigarette inhaler；
Described cloud of dust inhaler includes the hermetic container (8) being connected with described cloud of dust generation pipeline (5),
By being provided with the base plate (13) of accommodating animal at bottom position in described container, and for the dirt not sucked
Plume goes out the cloud of dust effuser (9) reclaimed.
Fine particle suction apparatus for building animal injury model the most according to claim 1,
It is characterized in that, described constant speed regulator part includes frequency conversion constant speed regulator (1) and the spiral shell being connected
Bar batcher (2), described screw rod batcher (2) is through described dust storage warehouse (3) and stretches into institute
State cloud of dust generation pipeline (5), and it is even to realize flue dust by the regulation of described frequency conversion constant speed regulator (1)
Speed flows into described cloud of dust generation pipeline (5).
Fine particle for building animal injury model the most according to claim 1 and 2 sucks
Device, it is characterised in that described dust storage warehouse (3) is Y type funnel-shaped structure, described screw rod is fixed
Measuring device (2) stretches into described cloud of dust generation pipeline through bell mouth and through described dust storage warehouse (3)
(5), when described screw rod batcher (2) rotates, can drive flue dust at the uniform velocity from dust storage warehouse (3)
Enter described cloud of dust generation pipeline (5).
4. according to the arbitrary described fine particle suction for building animal injury model of claim 1-3
Enter device, it is characterised in that described cloud of dust generation pipeline (5) is horizontally disposed L-type pipeline configuration,
Described dust storage warehouse (3) is arranged at the top of described cloud of dust generation pipeline (5) two-arm junction,
One arm of force pipeline of described cloud of dust generation pipeline (5) stretches into described flue dust inhaler and realizes cloud of dust conveying,
Another arm of force pipeline installs the first fan (6) away from the side of described dust storage warehouse (3).
5. according to the arbitrary described fine particle suction for building animal injury model of claim 1-4
Entering device, it is characterised in that in described cloud of dust inhaler, described cloud of dust effuser (9) is through described
Base plate (13) and with described base plate (13) perpendicular setting, the top of described cloud of dust effuser (9)
And sidewall is provided with pore (14) and flows out recovery for the cloud of dust.
6. according to the arbitrary described fine particle suction for building animal injury model of claim 1-5
Enter device, it is characterised in that the side-walls of described cloud of dust effuser (9) is provided with some longitudinal flutings can
Insert baffle plate (10), formed between described baffle plate (10) and described base plate (13) to house and treat that contamination is dynamic
The space of thing.
7. according to the arbitrary described fine particle suction for building animal injury model of claim 1-6
Entering device, it is characterised in that described hermetic container (8) is cylindrical structure container, the described cloud of dust is sent out
Raw pipeline (5) stretch to described hermetic container by tip portion, the top of described hermetic container (8)
Face is connected with column side wall hasp lock, it is achieved mobilizable airtight connection.
8. according to the arbitrary described fine particle suction for building animal injury model of claim 1-7
Enter device, it is characterised in that the top of described hermetic container (8) is provided with the second fan (7), with
Fully by cloud of dust mix homogeneously.
9. according to the arbitrary described fine particle suction for building animal injury model of claim 1-8
Enter device, it is characterised in that described suction apparatus also includes the dirt being connected with described cloud of dust withdrawer
Cigarette withdrawer, it is achieved do not suck the recovery of the cloud of dust.
Fine particle for building animal injury model the most according to claim 9 sucks dress
Put, it is characterised in that described cloud of dust withdrawer includes the connecting tube being connected with described cloud of dust inhaler
(11), described connecting tube (11) be positioned at described base plate (13) lower section and with described cloud of dust effuser (9)
Being connected, described connecting tube (11) stretches into returnable (12), is returned by the cloud of dust not sucked by animal
Receive to described returnable (12).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610348563.9A CN105853020B (en) | 2016-05-24 | 2016-05-24 | It is a kind of for constructing the fine particle suction apparatus of animal injury model |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610348563.9A CN105853020B (en) | 2016-05-24 | 2016-05-24 | It is a kind of for constructing the fine particle suction apparatus of animal injury model |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105853020A true CN105853020A (en) | 2016-08-17 |
| CN105853020B CN105853020B (en) | 2019-01-01 |
Family
ID=56635810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610348563.9A Active CN105853020B (en) | 2016-05-24 | 2016-05-24 | It is a kind of for constructing the fine particle suction apparatus of animal injury model |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105853020B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111758585A (en) * | 2020-07-14 | 2020-10-13 | 山东科技大学 | Coal industry pneumoconiosis animal model dust inhalation experimental device |
| CN111821061A (en) * | 2020-07-14 | 2020-10-27 | 山东科技大学 | Dust inhalation simulation experiment bin for pneumoconiosis mouse |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5297502A (en) * | 1993-05-05 | 1994-03-29 | Jaeger Rudolf J | Modular reversible-flow-past nasopulmonary respiratory dosing system for laboratory animals |
| CN1817324A (en) * | 2006-02-17 | 2006-08-16 | 范维林 | Dynamic inhalational contamination experimental instrument with solid-phase dust |
| CN202110166U (en) * | 2011-05-26 | 2012-01-11 | 山西大学 | Dynamic toxicant exposure device for toxic gas |
| CN104546214A (en) * | 2014-11-27 | 2015-04-29 | 郭光华 | Smoke simulation device for lung injury experiment |
| CN206261694U (en) * | 2016-05-24 | 2017-06-20 | 福建卫生职业技术学院 | A kind of fine particle suction apparatus for building animal injury model |
-
2016
- 2016-05-24 CN CN201610348563.9A patent/CN105853020B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5297502A (en) * | 1993-05-05 | 1994-03-29 | Jaeger Rudolf J | Modular reversible-flow-past nasopulmonary respiratory dosing system for laboratory animals |
| CN1817324A (en) * | 2006-02-17 | 2006-08-16 | 范维林 | Dynamic inhalational contamination experimental instrument with solid-phase dust |
| CN202110166U (en) * | 2011-05-26 | 2012-01-11 | 山西大学 | Dynamic toxicant exposure device for toxic gas |
| CN104546214A (en) * | 2014-11-27 | 2015-04-29 | 郭光华 | Smoke simulation device for lung injury experiment |
| CN206261694U (en) * | 2016-05-24 | 2017-06-20 | 福建卫生职业技术学院 | A kind of fine particle suction apparatus for building animal injury model |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111758585A (en) * | 2020-07-14 | 2020-10-13 | 山东科技大学 | Coal industry pneumoconiosis animal model dust inhalation experimental device |
| CN111821061A (en) * | 2020-07-14 | 2020-10-27 | 山东科技大学 | Dust inhalation simulation experiment bin for pneumoconiosis mouse |
| CN111758585B (en) * | 2020-07-14 | 2022-03-18 | 山东科技大学 | Coal industry pneumoconiosis animal model dust inhalation experimental device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105853020B (en) | 2019-01-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE102018008259A1 (en) | Filter systems for suspended particles with particle sizes from 400 pm to ≤500 μm and their use | |
| CN206261694U (en) | A kind of fine particle suction apparatus for building animal injury model | |
| CN103861411A (en) | Bionic air purification method and special bionic lung device | |
| CN106474605A (en) | A kind of atomizer device | |
| CN206354183U (en) | A kind of pouity dwelling place with air-cleaning function | |
| CN103111141A (en) | Washing-type air purifier | |
| CN105853020A (en) | Fine particle inhaling device for building animal injury model | |
| CN208741589U (en) | A kind of sputum aspirator for paediatrics | |
| CN206676144U (en) | A kind of plant gas purifier | |
| CN102580474A (en) | Air purifying and moistening machine | |
| CN219494338U (en) | High-speed centrifugal movement water impact negative oxygen ion production liner device | |
| CN208612645U (en) | Grinding device is used in a kind of anti-adhered medicament production | |
| CN206158778U (en) | Multidirectional local dust removal ventilation system of flexible | |
| CN205903752U (en) | Interior decoration construction dust isolating device | |
| CN201840965U (en) | Serial connection sheet type waste gas absorption device | |
| CN208878166U (en) | A kind of Mobile medical aerosol efficient absorption device | |
| CN107560339A (en) | A kind of good biomass granulation drying plant of environment protecting | |
| CN203955676U (en) | Firecracker setting-off safety and environmental protection device | |
| CN207477813U (en) | Extension wears formula air filtration unit | |
| RU89392U1 (en) | DRY SALT AEROSOL GENERATOR | |
| CN204911110U (en) | Be used for fashioned dust collecting device of living beings granule | |
| CN206535360U (en) | A kind of dedusting ventilation unit of environmental protection | |
| CN207269688U (en) | A kind of Mosquito killer lamp with purification function | |
| CN206593924U (en) | A kind of environmental protection atmosphere sampler | |
| CN206603995U (en) | A kind of atomizer device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |