CN105770634A - 一种治疗闭经的中药组合物 - Google Patents

一种治疗闭经的中药组合物 Download PDF

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CN105770634A
CN105770634A CN201610222916.0A CN201610222916A CN105770634A CN 105770634 A CN105770634 A CN 105770634A CN 201610222916 A CN201610222916 A CN 201610222916A CN 105770634 A CN105770634 A CN 105770634A
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汤华淑
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Abstract

本发明涉及一种治疗闭经的中药组合物，其中药原料及重量份配比为：熟地黄10‑30份、白蒺藜5‑25份、三棱5‑20份、鹿角胶5‑25份、马鞭草5‑25份、急性子5‑20份、卵叶水芹5‑25份、玫瑰花5‑25份、南瓜藤5‑25份、瞿麦5‑20份、银紫丹参5‑25份、穿山甲5‑20份、仙茅5‑25份、小肺筋草5‑25份、二色补血草5‑25份、桂枝5‑20份、薜荔根5‑25份、矮地茶5‑25份、兰石草果5‑20份、黄毛榕5‑25份、牡丹皮5‑20份、豇豆壳5‑25份、甘草5‑15份。本发明的中药组合物具有温补肝肾、补气益血、温经通脉、行气化瘀、活血调经的功效，其治疗闭经疗效显著，作用可靠。

Description

一种治疗 闭经 的中药组合物
技术领域
本发明涉及一种传统草药的未确定结构的医药配制品，尤其是一种治疗闭经的中药组合物。
背景技术
闭经即无月经，是妇产科病中常见的症状。闭经或为生理性或为病理性现象。生理状态下，如青春前期、妊娠期、哺乳期和绝经后期无月经属正常现象。凡年过 18 岁仍未行经者称为原发性闭经；在***以后，正常绝经以前的任何时间内（妊娠或哺乳期除外），月经闭止超过6个月者称为继发性闭经。近年来，随着生活压力的增大，很多女性在绝经前就过早出现了闭经的现象。闭经对女性身心健康影响很大。目前，临床上采用雌、孕激素促进子宫内膜增生和剥落，或采用雌、孕激素对先天性卵巢发育不良或卵巢功能受到抑制或破坏以致功能衰竭者进行人工周期治疗，以出现月经样的周期性撤药性出血，一方面纠正患者的生理和心理状态，另一方面促进生殖器官和***有一定程度的发育。但是，雌、孕激素只能带来短暂的来潮，并且人体会对性激素类西药产生依赖性。
中医认为，闭经是由于肝肾不足，气血亏虚，血脉失通所致。有虚实之分，虚者多因气血不足和肾虚，实者多由寒凝、气滞和血瘀。
根据中医理论，针对闭经的发病机理，采用温补肝肾、补气益血、温经通脉、行气化瘀、活血调经的治法，进行辩证配伍组方，以达到标本兼治的目的。
发明内容
为了克服现有技术中治疗闭经存在的不足，本发明提供一种配制简便、成本低、疗效显著、无副作用的治疗闭经的中药组合物。
本发明解决其技术问题所采用的技术方案是：一种治疗闭经的中药组合物，其特征在于：其中药原料及重量份配比为：熟地黄10-30份、白蒺藜5-25份、三棱5-20份、鹿角胶5-25份、马鞭草5-25份、急性子5-20份、卵叶水芹5-25份、玫瑰花5-25份、南瓜藤5-25份、瞿麦5-20份、银紫丹参5-25份、穿山甲5-20份、仙茅5-25份、小肺筋草5-25份、二色补血草5-25份、桂枝5-20份、薜荔根5-25份、矮地茶5-25份、兰石草果5-20份、黄毛榕5-25份、牡丹皮5-20份、豇豆壳5-25份、甘草5-15份。
本发明的优选技术方案是：一种治疗闭经的中药组合物，其特征在于：其中药原料及重量份配比为：熟地黄20份、白蒺藜15份、三棱10份、鹿角胶15份、马鞭草15份、急性子10份、卵叶水芹15份、玫瑰花15份、南瓜藤15份、瞿麦10份、银紫丹参15份、穿山甲10份、仙茅15份、小肺筋草15份、二色补血草15份、桂枝10份、薜荔根15份、矮地茶15份、兰石草果10份、黄毛榕15份、牡丹皮10份、豇豆壳15份、甘草10份。
本发明中药组合物是在传统中医理论和临床经验指导下，精选药物组方。本发明中药组合物中：熟地黄具有补血养阴、填精益髓的功效；白蒺藜具有疏肝解郁、祛风明目的功效；三棱具有破血行气、消积止痛的功效；鹿角胶具有温补肝肾、益精养血的功效；马鞭草具有清热解毒、活血散瘀、利水消肿的功效；急性子具有行瘀降气、软坚散结的功效；卵叶水芹具有补气益血、止血、利尿的功效；玫瑰花具有行气解郁、活血调经的功效；南瓜藤具有平肝和胃、通经络、利血脉、滋肾水的功效；瞿麦具有利尿通淋、破血通经的功效；银紫丹参具有活血祛瘀、利湿解毒的功效；穿山甲具有活血通络、消肿排脓、祛风止痛、通乳的功效；仙茅具有补肾助阳、益精血、强筋骨、行血消肿的功效；小肺筋草具有清热、润肺止咳、活血调经、杀虫的功效；二色补血草具有补血止血、散瘀调经、益脾健胃的功效；桂枝具有发汗解肌、温经通脉、助阳化气、散寒止痛的功效；薜荔根具有祛风除湿、舒筋通络的功效；矮地茶具有止咳平喘、清利湿热、活血化瘀的功效；兰石草果具有行气活血、调经止痛的功效；黄毛榕具有健脾益气、活血祛风的功效；牡丹皮具有清热凉血、活血散瘀的功效；豇豆壳具有补肾健脾、利水消肿、镇痛解毒的功效；甘草具有补脾益气、清热解毒、祛痰止咳、调和诸药的功效。本发明精选药物组方，其药物组分经辩证配伍，在作用上相互佐助，共奏温补肝肾、补气益血、温经通脉、行气化瘀、活血调经的功效，对闭经的治疗达到标本兼治。
本发明组合物的组分均采用天然的中药原料，其配制简便、药源广、成本低。本发明遵循中医的处方用药原则，各种组分药物采用水煎服用。经临床应用验证，其疗效显著可靠，药性平和，未出现毒副作用，有效率达95%，治愈率76.5%。
具体实施方式
下面结合实施例对本发明作进一步说明。
实施例1
一种治疗闭经的中药组合物，其中药原料及重量配比为：熟地黄20g、白蒺藜15g、三棱10g、鹿角胶15g、马鞭草15g、急性子10g、卵叶水芹15g、玫瑰花15g、南瓜藤15g、瞿麦10g、银紫丹参15g、穿山甲10g、仙茅15g、小肺筋草15g、二色补血草15g、桂枝10g、薜荔根15g、矮地茶15g、兰石草果10g、黄毛榕15g、牡丹皮10g、豇豆壳15g、甘草10g。
实施例2
一种治疗闭经的中药组合物，其中药原料及重量配比为：熟地黄15g、白蒺藜25g、三棱12g、鹿角胶20g、马鞭草5g、急性子15g、卵叶水芹10g、玫瑰花20g、南瓜藤5g、瞿麦15g、银紫丹参10g、穿山甲20g、仙茅5g、小肺筋草25g、二色补血草10g、桂枝20g、薜荔根5g、矮地茶25g、兰石草果12g、黄毛榕20g、牡丹皮5g、豇豆壳25g、甘草12g。
实施例3
一种治疗闭经的中药组合物，其中药原料及重量配比为：熟地黄25g、白蒺藜5g、三棱15g、鹿角胶10g、马鞭草20g、急性子5g、卵叶水芹25g、玫瑰花10g、南瓜藤20g、瞿麦5g、银紫丹参25g、穿山甲12g、仙茅20g、小肺筋草5g、二色补血草25g、桂枝12g、薜荔根20g、矮地茶5g、兰石草果15g、黄毛榕10g、牡丹皮20g、豇豆壳5g、甘草15g。
实施例4
一种治疗闭经的中药组合物，其中药原料及重量配比为：熟地黄10g、白蒺藜20g、三棱5g、鹿角胶25g、马鞭草10g、急性子20g、卵叶水芹5g、玫瑰花25g、南瓜藤10g、瞿麦20g、银紫丹参5g、穿山甲15g、仙茅10g、小肺筋草20g、二色补血草5g、桂枝15g、薜荔根10g、矮地茶20g、兰石草果5g、黄毛榕25g、牡丹皮12g、豇豆壳20g、甘草5g。
实施例5
一种治疗闭经的中药组合物，其中药原料及重量配比为：熟地黄30g、白蒺藜10g、三棱20g、鹿角胶5g、马鞭草25g、急性子12g、卵叶水芹20g、玫瑰花5g、南瓜藤25g、瞿麦12g、银紫丹参20g、穿山甲5g、仙茅25g、小肺筋草10g、二色补血草20g、桂枝5g、薜荔根25g、矮地茶10g、兰石草果20g、黄毛榕5g、牡丹皮15g、豇豆壳10g、甘草8g。
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下：将组方的中药原料放入容器中，加冷水漫过药面，浸泡15～20分钟，再加水没过药面约6厘米，进行第一次煎煮，未沸前采用武火煎煮，沸后用文火煎煮20～30分钟；第二次煎煮，加水没过药面约4厘米，水沸后煎煮15～20分钟。两次煎煮取汁，合并。
本发明以实施例1所给出的一种治疗闭经的中药组合物，做临床疗效总结如下：
一、一般性资料：本中药组合物应用于临床观察病例60例，年龄18～45岁。
二、诊断标准：
1、年逾 18 周岁女子，月经尚未初潮者，属原发性闭经；
2、女子已行经而又中断3个月以上者，属继发性闭经；
3、须与妊娠期、哺乳期、绝经期等生理性停经相鉴别。
三、用法用量：临床应用时，一日一剂，水煎两遍取汁约400ml，分早、晚两次空腹温服。六天为一疗程。治疗期间忌生冷辛辣刺激之物。
四、疗效标准：
(1)痊愈：月经来潮，连续 3 次以上正常行经；
(2)有效：月经恢复来潮。但***未正常；
(3)无效：月经仍未来潮。
五、治疗效果：该临床观察病例中，服药3-8个疗程，痊愈46例，随访未见复发；有效11例，无效3例。治疗期间未发生毒副作用。
六、典型病例：
病例1：
崔某，29岁。患者诉1年前行***术后闭经，注射***20毫克2次仍未行经。诊见：精神倦怠，乏力，食少，面色无华，头晕，记忆力减退，舌质淡，苔薄白，脉沉细弱。诊断为：继发性闭经。服用本发明中药组合物制备的药剂3个疗程，月经复现，经量较少，色淡红，质稀；继续服用 2个疗程，次月月经如期到来，月经量正常，治愈。随访至今再没出现闭经现象。
病例2：
杨某，19岁。患者自述：月经尚未来潮，头晕耳鸣，腰膝酸软，心悸烦热，失眠多梦，小便清长，夜尿多，大便溏。诊见：面色晦暗，舌质淡，苔白，脉沉弱。诊断为：原发性闭经。服用本发明中药组合物制备的药剂4个疗程，月经来潮，但经量较少，头晕耳鸣等症状完全消失；继续服用 2个疗程巩固治疗，每月月经如期到来，月经量正常。

Claims (2)

1.一种治疗闭经的中药组合物，其特征在于：其中药原料及重量份配比为：熟地黄10-30份、白蒺藜5-25份、三棱5-20份、鹿角胶5-25份、马鞭草5-25份、急性子5-20份、卵叶水芹5-25份、玫瑰花5-25份、南瓜藤5-25份、瞿麦5-20份、银紫丹参5-25份、穿山甲5-20份、仙茅5-25份、小肺筋草5-25份、二色补血草5-25份、桂枝5-20份、薜荔根5-25份、矮地茶5-25份、兰石草果5-20份、黄毛榕5-25份、牡丹皮5-20份、豇豆壳5-25份、甘草5-15份。
2.根据权利要求1所述一种治疗闭经的中药组合物，其特征在于：其中药原料及重量份配比为：熟地黄20份、白蒺藜15份、三棱10份、鹿角胶15份、马鞭草15份、急性子10份、卵叶水芹15份、玫瑰花15份、南瓜藤15份、瞿麦10份、银紫丹参15份、穿山甲10份、仙茅15份、小肺筋草15份、二色补血草15份、桂枝10份、薜荔根15份、矮地茶15份、兰石草果10份、黄毛榕15份、牡丹皮10份、豇豆壳15份、甘草10份。
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CN1095610A (zh) * 1993-05-24 1994-11-30 潘世庆 治疗、预防妇科疾患的药物制剂妇病康
CN103550736A (zh) * 2013-10-31 2014-02-05 孙丽 一种治疗瘀血阻络证型闭经病的中药
CN104758825A (zh) * 2015-03-26 2015-07-08 柳晖 一种治疗闭经的中药组合物
CN105749167A (zh) * 2016-04-12 2016-07-13 刘昌红 一种治疗闭经的中药组合物

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Publication number Priority date Publication date Assignee Title
CN1095610A (zh) * 1993-05-24 1994-11-30 潘世庆 治疗、预防妇科疾患的药物制剂妇病康
CN103550736A (zh) * 2013-10-31 2014-02-05 孙丽 一种治疗瘀血阻络证型闭经病的中药
CN104758825A (zh) * 2015-03-26 2015-07-08 柳晖 一种治疗闭经的中药组合物
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