CN105687589A - Chinese medicine for treating clinical wound and preparation method - Google Patents

Chinese medicine for treating clinical wound and preparation method Download PDF

Info

Publication number
CN105687589A
CN105687589A CN201610119947.3A CN201610119947A CN105687589A CN 105687589 A CN105687589 A CN 105687589A CN 201610119947 A CN201610119947 A CN 201610119947A CN 105687589 A CN105687589 A CN 105687589A
Authority
CN
China
Prior art keywords
radix
medicine
chinese medicine
root
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610119947.3A
Other languages
Chinese (zh)
Inventor
孙世成
张吉玲
丛榕
李霞
杜卫萍
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201610119947.3A priority Critical patent/CN105687589A/en
Publication of CN105687589A publication Critical patent/CN105687589A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/28—Mercury; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/648—Myriapods, e.g. centipedes or millipedes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/235—Foeniculum (fennel)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/346—Platycodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Insects & Arthropods (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention provides Chinese medicine for treating a clinical wound and a preparation method. The Chinese medicine can resist bacteria and eliminate inflammation, prevent wound infection, effectively promote wound healing and is high in curative rate. The Chinese medicine comprises medicine for external use and oral medicine, wherein the medicine for external use is prepared from sesame oil, cortex phellodendri, crinis trachycarpi, eucommia bark, a centipede, radix angelicae, a rehmannia root, radix lithospermi, apple seeds, a liquorice root, calomel, dragon's blood, fossil fragments, a platycodon root, calcined gypsum, red halloysite, pseudo-ginseng and aloes; the oral medicine is prepared from, by weight, peach kernels, carthamus tinctorious, fructus aurantii, polygonum multiflorum, a common clubmoss herb, fennel fruits, milkvetch roots, angelica sinensis, radix achyranthis bidentatae, a rehmannia root, rhizoma corydalis, a liquorice root, pseudo-ginseng, angelica sinensis, orange seeds, a root of phyllanthusreticulatus poir., myrrh, the skin of erinaceus europaeus L., Chinese sage herbs, a dipsacus root and safflower carthamus.

Description

The Chinese medicine of the clinical wound for the treatment of and preparation method
Technical field
The invention belongs to technical field of Chinese medicines, particularly to a kind of Chinese medicine treating clinical wound and preparation method。
Background technology
In surgical clinical, the conventional treatment methods such as various wounds are very common, wound infection, deep tissue pyogenic infection are incision and drainage, place sliver, regularly change dressings, use antibiotic etc., the zest that the medicine regularly changed dressings has is too strong, is unfavorable for wound healing, has increased the weight of the misery of patient。
Summary of the invention
It is an object of the present invention to provide a kind of Chinese medicine treating clinical wound and preparation method, it is possible to anti-inflammation, it is prevented that wound infection, effectively facilitated wound healing, and cure rate is high。
To achieve these goals, the present invention is realized by following measures:
A kind of Chinese medicine treating clinical wound, it includes medicine for external use and oral medicine, and medicine for external use is made up of the crude drug of following weight: Oleum Sesami 500g, Cortex Phellodendri 12g, charred Petiolus Trachycarpi 6g, Cortex Eucommiae 12g, Scolopendra 5g, Radix Angelicae Dahuricae 12g, Radix Rehmanniae 12g, Radix Arnebiae (Radix Lithospermi) 6g, Fructus Mali pumilae core 3g, Radix Glycyrrhizae 18g, Calomelas 9g, Sanguis Draxonis 6g, Os Draconis 9g, Radix Platycodonis 12g, Gypsum Fibrosum preparata 9g, Halloysitum Rubrum 9g, Radix Notoginseng 12g, Aloe 18g；Oral medicine includes the crude drug of following weight: Semen Persicae 12g, Flos Carthami 9g, Fructus Aurantii 12g, Radix Polygoni Multiflori 6g, Herba Lycopodii 20g, Fructus Foeniculi 12g, Radix Astragali 12g, Radix Angelicae Sinensis 12g, Radix Achyranthis Bidentatae 12g, Radix Rehmanniae 9g, Rhizoma Corydalis 12g, Radix Glycyrrhizae 9g, Radix Notoginseng 12g, Radix Angelicae Sinensis 20g, Semen Citri junoris 9, mountain Lens culinaris Medic. 6g, Myrrha 6g, Corium Erinacei Seu Hemiechianus 3g, Herba Salviae Chinensis 9g, Radix Dipsaci 15g, Flos Carthami 6g。
A kind of preparation method of the Chinese medicine treating clinical wound, method for preparing externally applied: Oleum Sesami is inserted container heating, when Oleum sesami temperature reaches 70 DEG C, above-mentioned Os Draconis and Scolopendra are added in Oleum Sesami and decocts 1 hour, add Cortex Phellodendri, the Cortex Eucommiae, the Radix Angelicae Dahuricae, the Radix Rehmanniae, Radix Arnebiae (Radix Lithospermi), charred Petiolus Trachycarpi, Fructus Mali pumilae core, Radix Glycyrrhizae, Calomelas, Sanguis Draxonis, Radix Platycodonis, Gypsum Fibrosum preparata, Halloysitum Rubrum, Radix Notoginseng and Aloe to continue fried 40 minutes, until one-tenth pasty medicament, to obtain final product。
A kind of preparation method of the Chinese medicine of the clinical wound of described treatment, oral medicine preparation method: weigh above-mentioned raw materials medicine, mixing, add the water of 5-8 times of weight, soak 1 hour, heating is boiled 1 hour, filters to get filtrate；Medicinal residues add the water of 3-5 times of weight, soak 20 minutes, and heating is boiled 30 hours, filter, and merge filtrate, add 15g yellow wine, mix homogeneously。
The pharmacologically active of each crude drug is as follows:
Oleum Sesami, is used as outward ointment machin plaster substrate；Outer application, such as scald, burn, skin ulcer etc., with Oleum Sesami and medicine, applies in affected part, dry does not split, and good is fast。
Cortex Phellodendri, has heat clearing and damp drying, and pathogenic fire purging is except steaming, effect of detoxification sore treatment；For damp-heat dysentery, jaundice dark coloured urine, leukorrhagia pudendal pruritus, the puckery pain of pyretic stranguria, beriberi flaccidity is knitted, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema eczema。
Charred Petiolus Trachycarpi, be used for spitting blood, epistaxis, have blood in stool, the card such as metrorrhagia。Astringing to arrest bleeding: cure mainly spitting of blood, haematemesis, epistaxis, have blood in stool, metrorrhagia, the card such as menorrhagia and without the stagnant person of the stasis of blood。
The Cortex Eucommiae, there is invigorating the liver and kidney, control spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, hypertension, antiabortive effect, immune system, hormonal system, central nervous system, blood circulation and urinary system are had adjustment effect in various degree, the excited Pituitary Adrenalcortical system of Cortex Eucommiae energy, adrenal cortex reinforcing function。
Scolopendra, expellings wind and relieving convulsion；Removing obstruction in the collateral to relieve pain；Dispersing pathogen accumulation。Main infantile convulsion, epilepsy；Spasm is twitched；Middle air port?；Tetanus；Rheumatoid arthritis stubborn；Migraine and general headache；Venom；Skin infection；Scrofula。For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom。
The Radix Angelicae Dahuricae, dispels the wind, dampness, detumescence, pain relieving。Controlling headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp is suffered from abdominal pain, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies。
The Radix Rehmanniae, has YIN nourishing and the production of body fluid promoting effect thirsty for Tianjin wound, and interior-heat is quenched one's thirst。Control epidemic febrile disease impairment of YIN, dryness of the intestine constipation。
Radix Arnebiae (Radix Lithospermi), removing heat from blood, invigorate blood circulation, heat clearing away, removing toxic substances。Control warm macule, jaundice due to damp-heat, purpura, tell, be defeated in battle, hematuria, stranguria with turbid discharge, constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer。
Radix Glycyrrhizae, has antiinflammatory, anti-allergic effects
Calomelas, external treatment is used for scabies, stubborn dermatitis, ecthyma, syphilis, skin infection, eczema。
Sanguis Draxonis, for traumatic injury, trusted subordinate's stasis of blood pain, traumatic hemorrhage, skin infection is not held back。
Os Draconis, tranquillization with heavy prescription tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, stop blooding astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing。Controlling infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating, stranguria with turbid discharge of passing out semen, and tells nosebleed and has blood in stool, and bleeding not during menses, dysentery proctoptosis, ulcer does not close up for a long time。
Radix Platycodonis, lung qi dispersing, sore-throat relieving, eliminate the phlegm, evacuation of pus。For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus。
Gypsum Fibrosum preparata, heat clearing away, convergence, granulation promoting。Curing mainly calentura, high fever does not move back, thirsty agitation, full and large pulse；Epidemic febrile disease high heat, body sends out macule；The high Sheng of stomach-fire, gingival swelling and pain, halitosis；Wind heat attacks lung, and high heat syndrome cough is breathed heavily。
Halloysitum Rubrum, external treatment skin infection is burst for a long time and is not held back, and eczema pus is contaminated。
Radix Notoginseng, dissipating blood stasis stops blooding, and subduing swelling and relieving pain is used for spitting blood, and spits blood, and epistaxis is had blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen twinge, tumbling and swelling。
Aloe, pathogenic fire purging；Removing toxic substances；Blood stasis dispelling；Parasite killing。Argument is red；Constipation；Nebulousurine；Hematuria；Pediatric epilepsy scared；Infantile malnutrition；Burn and scald；Women's amenorrhea；Hemorrhoid；Scabies；Carbuncle furuncle and phyma poison；Traumatic injury；Bactericidal action, antiinflammatory action, moistening beautification function, let out effect under stomach invigorating, the heart tonifying effect of invigorating blood circulation, immune and regeneration, immune and antitumor action, Detoxication, anti-aging effects, analgesia, sedation, anti-sunlight function。
Semen Persicae, has blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, effect of relieving cough and asthma。For amenorrhea dysmenorrhea, abdominal mass abdominal mass mass in the abdomen, lung abscess acute appendicitis, injury from falling down, dryness of the intestine constipation, cough and asthma。
Flos Carthami, promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, contribute to controlling amenorrhea, dysmenorrhea, lochia, obstruction of qi in the chest and cardialgia, the stagnant stomachache of the stasis of blood, breast side of body twinge, traumatic injury, skin infection swell and ache curative effect。Blood circulation promoting and blood stasis dispelling, wet dissipation is had to go the effect swollen。
Fructus Aurantii, has effect of regulating the flow of QI to ease the stomach, the stagnant relieving distension of row, cures mainly the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention;Gastroptosis, proctoptosis, the disease such as sub-official's prolapsus。
Radix Polygoni Multiflori, nourishing the blood and yin；Loosening bowel to relieve constipation；Preventing the attack (or recurrence) of malaria；Dispel the wind；Removing toxic substances。Main blood deficiency Light-headedness；Cardiopalmus；Insomnia；The soreness of the waist and knees of the hepatic and renal YIN deficiency；Early whitening of beard and hair；Tinnitus；Seminal emission；Dryness of the intestine constipation；Chronic malaria body is empty；Rubella pruritus；Carbuncle sore；Scrofula；Hemorrhoid。
Herba Lycopodii, expelling wind and cold. dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral。For anemofrigid-damp arthralgia, muscle arteries and veins contracture pain carbuncle。External is controlled osteopatia sprain and is swollen and ache。
Fructus Foeniculi, suffers from abdominal pain for colic of cold type, the testis swelling and hanging down of either of the testes, dysmenorrhea, few abdomen cold type of pain, abdominal distention, lack of appetite and vomiting。
The Radix Astragali, returns lung meridian, has tonifying Qi and lifting yang, benefit to defend the function of consolidating superficial resistance。
Radix Angelicae Sinensis, enriches blood；Invigorate blood circulation；Menstruction regulating and pain relieving；Moisturize laxation。The all cards of main blood deficiency；Menoxenia；Amenorrhea；Dysmenorrhea；Lump in the abdomen knot is poly-；Metrorrhagia；Asthenia cold abdominalgia；Flaccidity syndrome and arthralgia syndrome；Numbness of the skin；Dryness of the intestine dyschezia；Weight after bloody dysentery；Ulcer sores；Injury from falling down。
Radix Achyranthis Bidentatae, effect: eliminating blood stasis and inducing menstruation, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, conducting blood to flow downwards；Cure mainly: for amenorrhea, dysmenorrhea, soreness of waist and knee joint, muscles and bones is unable, stranguria, edema, headache, dizziness。
Rhizoma Corydalis, for whole body each portion qi depression to blood stasis pain, dysmenorrhea, amenorrhea, lump in the abdomen, postpartum stagnation, injury from falling down, hernia is had a pain。
Semen Citri junoris, regulate the flow of vital energy, pain relieving, inducing diuresis for treating stranguria syndrome。Control hernia, gonorrhea, lumbago。
Mountain Lens culinaris Medic., antiinflammatory, convergence, antidiarrheal。Cure mainly dysentery, enteritis, tuberculosis of intestine, hepatitis, nephritis, infantile malnutrition。
Myrrha, has dissipating blood stasis analgesic therapy, effect of detumescence and promoting granulation。Being usually used in obstruction of qi in the chest and cardialgia, gastralgia, dysmenorrhea amenorrhea, postpartum stagnation, abdominal mass is suffered from abdominal pain, rheumatic arthralgia, traumatic injury, the treatment of the diseases such as carbuncle skin infection。
Corium Erinacei Seu Hemiechianus, has blood-activating analgetic, astringing to arrest bleeding, effect of controlling nocturnal emission with astringent drugs。It is usually used in gastralgia, metrorrhagia, has blood in stool, discharging fresh blood stool, proctoptosis, hemorrhoid, seminal emission, the enuresis。
Herba Salviae Chinensis, function cures mainly: heat-clearing and toxic substances removing, blood circulation promoting regulates qi pain relieving。Swell for acute, chronic hepatitis, gastral cavity side of body distending pain, damp-heat vaginal discharge, mastitis, furuncle。
Radix Dipsaci, tonifying liver, bone and muscle strengthening, determine meridians, only through in (muscles and bones) ache, antiabortive, be suitable for controlling married woman leucorrhea, tissue regeneration promoting blood, removing blood stasis with potent drugs blood, fall stillborn fetus, and cough-relieving is coughed hemoptysis, controls red white turbid urine。
The method have the benefit that
1, the present invention adopts said medicine, non-stimulated, has no side effect, and has anti-inflammation, promotes granulation growth analgesic activity。
2, clinical observation can effectively prevent wound infection, has positive effect for wound healing。
Detailed description of the invention:
Below by way of specific embodiment, the present invention is described in further detail; but it not limitation of the present invention, those skilled in the art's basic thought according to the present invention, it is possible to make a lot of amendment or improve; without departing from the basic thought of the present invention, all in protection scope of the present invention。
A kind of Chinese medicine treating clinical wound, it includes medicine for external use and oral medicine, and medicine for external use is made up of the crude drug of following weight: Oleum Sesami 500g, Cortex Phellodendri 12g, charred Petiolus Trachycarpi 6g, Cortex Eucommiae 12g, Scolopendra 5g, Radix Angelicae Dahuricae 12g, Radix Rehmanniae 12g, Radix Arnebiae (Radix Lithospermi) 6g, Fructus Mali pumilae core 3g, Radix Glycyrrhizae 18g, Calomelas 9g, Sanguis Draxonis 6g, Os Draconis 9g, Radix Platycodonis 12g, Gypsum Fibrosum preparata 9g, Halloysitum Rubrum 9g, Radix Notoginseng 12g, Aloe 18g；Oral medicine includes the crude drug of following weight: Semen Persicae 12g, Flos Carthami 9g, Fructus Aurantii 12g, Radix Polygoni Multiflori 6g, Herba Lycopodii 20g, Fructus Foeniculi 12g, Radix Astragali 12g, Radix Angelicae Sinensis 12g, Radix Achyranthis Bidentatae 12g, Radix Rehmanniae 9g, Rhizoma Corydalis 12g, Radix Glycyrrhizae 9g, Radix Notoginseng 12g, Radix Angelicae Sinensis 20g, Semen Citri junoris 9, mountain Lens culinaris Medic. 6g, Myrrha 6g, Corium Erinacei Seu Hemiechianus 3g, Herba Salviae Chinensis 9g, Radix Dipsaci 15g, Flos Carthami 6g。
A kind of preparation method of the Chinese medicine treating clinical wound, method for preparing externally applied: Oleum Sesami is inserted container heating, when Oleum sesami temperature reaches 70 DEG C, above-mentioned Os Draconis and Scolopendra are added in Oleum Sesami and decocts 1 hour, add Cortex Phellodendri, the Cortex Eucommiae, the Radix Angelicae Dahuricae, the Radix Rehmanniae, Radix Arnebiae (Radix Lithospermi), charred Petiolus Trachycarpi, Fructus Mali pumilae core, Radix Glycyrrhizae, Calomelas, Sanguis Draxonis, Radix Platycodonis, Gypsum Fibrosum preparata, Halloysitum Rubrum, Radix Notoginseng and Aloe to continue fried 40 minutes, until one-tenth pasty medicament, to obtain final product。
A kind of preparation method of the Chinese medicine treating clinical wound, oral medicine preparation method: weigh above-mentioned raw materials medicine, mixing, add the water of 5-8 times of weight, soak 1 hour, heating is boiled 1 hour, filters to get filtrate；Medicinal residues add the water of 3-5 times of weight, soak 20 minutes, and heating is boiled 30 hours, filter, and merge filtrate, add 15g yellow wine, mix homogeneously。
Clinical data
1. data and method
1.1 select, and clinic did operating patient 110 example, and wound is positioned at extremity, chest, abdominal part。
1.2 usings method: medicine for external use: after being cleared up by wound, smear 2-3 times/day；Oral medicine: twice sooner or later。
2. therapeutic effect
3. conclusion: the medicine of the present invention can promote wound healing, 1-2 days, general 3-5 days of surgical operation, evident in efficacy。

Claims (3)

1. the Chinese medicine treating clinical wound, it is characterised in that it includes medicine for external use and oral medicine, and medicine for external use is made up of the crude drug of following weight: Oleum Sesami 500g, Cortex Phellodendri 12g, charred Petiolus Trachycarpi 6g, Cortex Eucommiae 12g, Scolopendra 5g, Radix Angelicae Dahuricae 12g, Radix Rehmanniae 12g, Radix Arnebiae (Radix Lithospermi) 6g, Fructus Mali pumilae core 3g, Radix Glycyrrhizae 18g, Calomelas 9g, Sanguis Draxonis 6g, Os Draconis 9g, Radix Platycodonis 12g, Gypsum Fibrosum preparata 9g, Halloysitum Rubrum 9g, Radix Notoginseng 12g, Aloe 18g；Oral medicine includes the crude drug of following weight: Semen Persicae 12g, Flos Carthami 9g, Fructus Aurantii 12g, Radix Polygoni Multiflori 6g, Herba Lycopodii 20g, Fructus Foeniculi 12g, Radix Astragali 12g, Radix Angelicae Sinensis 12g, Radix Achyranthis Bidentatae 12g, Radix Rehmanniae 9g, Rhizoma Corydalis 12g, Radix Glycyrrhizae 9g, Radix Notoginseng 12g, Radix Angelicae Sinensis 20g, Semen Citri junoris 9, mountain Lens culinaris Medic. 6g, Myrrha 6g, Corium Erinacei Seu Hemiechianus 3g, Herba Salviae Chinensis 9g, Radix Dipsaci 15g, Flos Carthami 6g。
2. the preparation method of the Chinese medicine of the clinical wound for the treatment of described in a claim 1, it is characterized in that, method for preparing externally applied: Oleum Sesami is inserted container heating, when Oleum sesami temperature reaches 70 DEG C, above-mentioned Os Draconis and Scolopendra are added in Oleum Sesami and decocts 1 hour, adding Cortex Phellodendri, charred Petiolus Trachycarpi, the Cortex Eucommiae, the Radix Angelicae Dahuricae, the Radix Rehmanniae, Radix Arnebiae (Radix Lithospermi), Fructus Mali pumilae core, Radix Glycyrrhizae, Calomelas, Sanguis Draxonis, Radix Platycodonis, Gypsum Fibrosum preparata, Halloysitum Rubrum, Radix Notoginseng and Aloe to continue fried 40 minutes, until becoming pasty medicament, obtaining final product。
3. the preparation method of the Chinese medicine of the clinical wound for the treatment of described in a claim 1, it is characterised in that oral medicine preparation method: weigh above-mentioned raw materials medicine, mixing, adds the water of 5-8 times of weight, soaks 1 hour, and heating is boiled 1 hour, filters to get filtrate；Medicinal residues add the water of 3-5 times of weight, soak 20 minutes, and heating is boiled 30 hours, filter, and merge filtrate, add 15g yellow wine, mix homogeneously。
CN201610119947.3A 2016-03-03 2016-03-03 Chinese medicine for treating clinical wound and preparation method Pending CN105687589A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610119947.3A CN105687589A (en) 2016-03-03 2016-03-03 Chinese medicine for treating clinical wound and preparation method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610119947.3A CN105687589A (en) 2016-03-03 2016-03-03 Chinese medicine for treating clinical wound and preparation method

Publications (1)

Publication Number Publication Date
CN105687589A true CN105687589A (en) 2016-06-22

Family

ID=56223796

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610119947.3A Pending CN105687589A (en) 2016-03-03 2016-03-03 Chinese medicine for treating clinical wound and preparation method

Country Status (1)

Country Link
CN (1) CN105687589A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107050234A (en) * 2016-11-10 2017-08-18 刁媛媛 A kind of pharmaceutical composition for treating soft tissue injury
CN111110723A (en) * 2020-01-21 2020-05-08 狄维华 Medicinal powder and medicinal liquor for treating wound and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1210000A (en) * 1997-09-03 1999-03-10 田明行 Ointment for wounds and sores and preparation thereof
CN1742916A (en) * 2005-09-28 2006-03-08 周崇阶 Zijin ointment for treating cold injury and scald
CN105250481A (en) * 2015-11-10 2016-01-20 北京市祖国红医疗科技中心（有限合伙） Medicine composition for treatment of blood stasis and preparation method and application thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1210000A (en) * 1997-09-03 1999-03-10 田明行 Ointment for wounds and sores and preparation thereof
CN1742916A (en) * 2005-09-28 2006-03-08 周崇阶 Zijin ointment for treating cold injury and scald
CN105250481A (en) * 2015-11-10 2016-01-20 北京市祖国红医疗科技中心（有限合伙） Medicine composition for treatment of blood stasis and preparation method and application thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107050234A (en) * 2016-11-10 2017-08-18 刁媛媛 A kind of pharmaceutical composition for treating soft tissue injury
CN111110723A (en) * 2020-01-21 2020-05-08 狄维华 Medicinal powder and medicinal liquor for treating wound and preparation method thereof

Similar Documents

Publication Publication Date Title
CN100417403C (en) Traditional Chinese medicine for treating cancer
CN101791377B (en) Traditional Chinese medicine preparation for post-operation rehabilitation of cervicitis and cervical hypertrophy
CN100551422C (en) A kind of endo-medicine for the treatment of intervertebral disk hernia
CN104324338A (en) Nursing patch for bedsore
CN104225138A (en) Traditional Chinese medicine for treating bedsore through oral administration and external washing and preparation method of traditional Chinese medicine
CN101972424B (en) Traditional Chinese medicine for treating cirrhosis ascites
CN106309611A (en) Plaster with effects of relaxing muscles and stimulating blood circulation
CN102626505A (en) Massaging paste based on Chinese medicinal herbs and preparation method thereof
CN1895434B (en) Medicine for treating hysteromyoma
CN104873851A (en) Internal and external traditional-Chinese-medicine composition for treating bedsore
CN105687589A (en) Chinese medicine for treating clinical wound and preparation method
CN105250878A (en) Traditional Chinese medicine for treating sub-acute infective endocarditis
CN102698047B (en) Chinese medicinal plaster for treating tumor
CN101953930B (en) Externally-applied traditional Chinese medicine for treating tinea capitis
CN104587206A (en) Medicament for treating bedsore and preparation method of medicament
CN104667105A (en) Chinese patent medicine for treating facial neuritis and preparation method for Chinese patent medicine
CN104491693A (en) Traditional Chinese medicine antibiotic cream for treating yang syndrome of ulcer
CN103341129A (en) External-application medicine for treating sprained ankle
CN102949544B (en) Chinese medicinal composition for specifically treating swelling of hands and feet of hemiplegic patients
CN102579607B (en) Chinese medicine composition for treating acne
CN100371016C (en) Chinese traditional medicine preparation for curing mastopathy in installments
CN103877489A (en) Medicine for treating bedsore
CN103223151A (en) Traditional Chinese medicinal composition for brightening and spot-removing and preparation method of preparation
CN102895564A (en) Chinese medicine for treating tubal nowhere and preparation method thereof
CN103494991B (en) Traditional Chinese medicine preparation for treating female metrorrhagia and preparation method thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20160622