CN105669864A - 抗人程序性死亡受体1抗体及其制备方法和用途 - Google Patents
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- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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- C07K—PEPTIDES
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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Abstract
Description
Claims (14)
Priority Applications (6)
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CN201510981105.4A CN105669864B (zh) | 2015-12-23 | 2015-12-23 | 抗人程序性死亡受体1抗体及其制备方法和用途 |
US16/066,024 US10774144B2 (en) | 2015-12-23 | 2016-12-19 | Human programmed cell death 1 receptor antibody, method of preparing same, and use thereof |
PCT/CN2016/110790 WO2017107885A1 (zh) | 2015-12-23 | 2016-12-19 | 抗人程序性死亡受体1抗体及其制备方法和用途 |
CN202110361321.4A CN112940123B (zh) | 2015-12-23 | 2016-12-19 | 抗人程序性死亡受体1抗体及其制备方法和用途 |
CN201680075496.6A CN108473580B (zh) | 2015-12-23 | 2016-12-19 | 抗人程序性死亡受体1抗体及其制备方法和用途 |
HK19100375.4A HK1258007A1 (zh) | 2015-12-23 | 2019-01-10 | 抗人程序性死亡受體1抗體及其製備方法和用途 |
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CN201510981105.4A CN105669864B (zh) | 2015-12-23 | 2015-12-23 | 抗人程序性死亡受体1抗体及其制备方法和用途 |
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CN105669864A true CN105669864A (zh) | 2016-06-15 |
CN105669864B CN105669864B (zh) | 2018-10-16 |
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CN201510981105.4A Active CN105669864B (zh) | 2015-12-23 | 2015-12-23 | 抗人程序性死亡受体1抗体及其制备方法和用途 |
CN202110361321.4A Active CN112940123B (zh) | 2015-12-23 | 2016-12-19 | 抗人程序性死亡受体1抗体及其制备方法和用途 |
CN201680075496.6A Active CN108473580B (zh) | 2015-12-23 | 2016-12-19 | 抗人程序性死亡受体1抗体及其制备方法和用途 |
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CN201680075496.6A Active CN108473580B (zh) | 2015-12-23 | 2016-12-19 | 抗人程序性死亡受体1抗体及其制备方法和用途 |
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US (1) | US10774144B2 (zh) |
CN (3) | CN105669864B (zh) |
HK (1) | HK1258007A1 (zh) |
WO (1) | WO2017107885A1 (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017107885A1 (zh) * | 2015-12-23 | 2017-06-29 | 杭州尚健生物技术有限公司 | 抗人程序性死亡受体1抗体及其制备方法和用途 |
WO2018153320A1 (zh) * | 2017-02-21 | 2018-08-30 | 上海君实生物医药科技股份有限公司 | 抗pd-l1抗体及其应用 |
US10513558B2 (en) | 2015-07-13 | 2019-12-24 | Cytomx Therapeutics, Inc. | Anti-PD1 antibodies, activatable anti-PD1 antibodies, and methods of use thereof |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA201890630A1 (ru) | 2015-09-01 | 2018-10-31 | Эйдженус Инк. | Антитела против pd-1 и способы их применения |
CA3046082A1 (en) | 2016-12-07 | 2018-06-14 | Agenus Inc. | Antibodies and methods of use thereof |
KR20220030956A (ko) | 2019-07-05 | 2022-03-11 | 오노 야꾸힝 고교 가부시키가이샤 | Pd-1/cd3 이중 특이성 단백질에 의한 혈액암 치료 |
WO2021025140A1 (ja) | 2019-08-08 | 2021-02-11 | 小野薬品工業株式会社 | 二重特異性タンパク質 |
AU2021242305A1 (en) * | 2020-03-26 | 2022-10-20 | Cureimmune Therapeutics Inc. | Anti-PD-1 antibodies and methods of use |
Citations (2)
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CN101213297A (zh) * | 2005-05-09 | 2008-07-02 | 小野药品工业株式会社 | 程序性死亡-1(pd-1)的人单克隆抗体及单独使用或与其它免疫治疗剂联合使用抗pd-1抗体来治疗癌症的方法 |
CN104987421A (zh) * | 2015-05-13 | 2015-10-21 | 北京比洋生物技术有限公司 | 抗ctla-4和pd-1的双重可变结构域免疫球蛋白 |
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BR0316880A (pt) * | 2002-12-23 | 2005-10-25 | Wyeth Corp | Anticorpos contra pd-1 e usos dos mesmos |
HUE047699T2 (hu) * | 2013-12-17 | 2020-05-28 | Hoffmann La Roche | Eljárások rákbetegségek kezelésére PD-1-tengelyhez kötõdõ antagonisták és taxánok alkalmazásával |
TWI681969B (zh) * | 2014-01-23 | 2020-01-11 | 美商再生元醫藥公司 | 針對pd-1的人類抗體 |
EP3498734B1 (en) | 2014-02-04 | 2021-09-01 | Pfizer Inc. | Combination of a pd-1 antagonist and a vegfr inhibitor for treating cancer |
CN105669864B (zh) * | 2015-12-23 | 2018-10-16 | 杭州尚健生物技术有限公司 | 抗人程序性死亡受体1抗体及其制备方法和用途 |
-
2015
- 2015-12-23 CN CN201510981105.4A patent/CN105669864B/zh active Active
-
2016
- 2016-12-19 WO PCT/CN2016/110790 patent/WO2017107885A1/zh active Application Filing
- 2016-12-19 US US16/066,024 patent/US10774144B2/en active Active
- 2016-12-19 CN CN202110361321.4A patent/CN112940123B/zh active Active
- 2016-12-19 CN CN201680075496.6A patent/CN108473580B/zh active Active
-
2019
- 2019-01-10 HK HK19100375.4A patent/HK1258007A1/zh unknown
Patent Citations (2)
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CN101213297A (zh) * | 2005-05-09 | 2008-07-02 | 小野药品工业株式会社 | 程序性死亡-1(pd-1)的人单克隆抗体及单独使用或与其它免疫治疗剂联合使用抗pd-1抗体来治疗癌症的方法 |
CN104987421A (zh) * | 2015-05-13 | 2015-10-21 | 北京比洋生物技术有限公司 | 抗ctla-4和pd-1的双重可变结构域免疫球蛋白 |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10513558B2 (en) | 2015-07-13 | 2019-12-24 | Cytomx Therapeutics, Inc. | Anti-PD1 antibodies, activatable anti-PD1 antibodies, and methods of use thereof |
WO2017107885A1 (zh) * | 2015-12-23 | 2017-06-29 | 杭州尚健生物技术有限公司 | 抗人程序性死亡受体1抗体及其制备方法和用途 |
CN108473580A (zh) * | 2015-12-23 | 2018-08-31 | 杭州尚健生物技术有限公司 | 抗人程序性死亡受体1抗体及其制备方法和用途 |
US10774144B2 (en) | 2015-12-23 | 2020-09-15 | Hangzhou Sumgen Biotechnology Co., Ltd | Human programmed cell death 1 receptor antibody, method of preparing same, and use thereof |
CN112940123A (zh) * | 2015-12-23 | 2021-06-11 | 石药集团巨石生物制药有限公司 | 抗人程序性死亡受体1抗体及其制备方法和用途 |
CN112940123B (zh) * | 2015-12-23 | 2022-10-21 | 石药集团巨石生物制药有限公司 | 抗人程序性死亡受体1抗体及其制备方法和用途 |
WO2018153320A1 (zh) * | 2017-02-21 | 2018-08-30 | 上海君实生物医药科技股份有限公司 | 抗pd-l1抗体及其应用 |
US11267890B2 (en) | 2017-02-21 | 2022-03-08 | Shanghai Junshi Biosciences Inc. | Anti-PD-L1 antibody and application thereof |
Also Published As
Publication number | Publication date |
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CN112940123B (zh) | 2022-10-21 |
US20190016799A1 (en) | 2019-01-17 |
CN112940123A (zh) | 2021-06-11 |
CN105669864B (zh) | 2018-10-16 |
US10774144B2 (en) | 2020-09-15 |
WO2017107885A1 (zh) | 2017-06-29 |
CN108473580A (zh) | 2018-08-31 |
HK1258007A1 (zh) | 2019-11-01 |
CN108473580B (zh) | 2021-04-27 |
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