CN105617023A - 一种具有提高免疫力的石斛保健品及其制备方法和应用 - Google Patents

一种具有提高免疫力的石斛保健品及其制备方法和应用 Download PDF

Info

Publication number
CN105617023A
CN105617023A CN201610071003.3A CN201610071003A CN105617023A CN 105617023 A CN105617023 A CN 105617023A CN 201610071003 A CN201610071003 A CN 201610071003A CN 105617023 A CN105617023 A CN 105617023A
Authority
CN
China
Prior art keywords
parts
immunity
preparation
efficacy
care product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201610071003.3A
Other languages
English (en)
Inventor
孙爱华
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201610071003.3A priority Critical patent/CN105617023A/zh
Publication of CN105617023A publication Critical patent/CN105617023A/zh
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/898—Orchidaceae (Orchid family)
    • A61K36/8984—Dendrobium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/85—Verbenaceae (Verbena family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

本发明属于中药领域，公开了一种具有提高免疫力功效的石斛保健品，含有石斛20份、红天葵18份、定心散20份、黄荆根15份、环草20份、小槐花20份、甘草6份，剂型是颗粒剂、片剂、胶囊剂，还公开了制备方法为加水煎煮，浓缩，醇沉，喷雾干燥，所得颗粒粉碎成干浸膏粉，加入辅料，制成所需制剂，还公开了其在制备具有提高免疫力功效保健品中的应用。

Description

一种具有提高免疫力的石斛保健品及其制备方法和应用
技术领域
本发明涉及中药制剂技术领域，具体涉及一种提高免疫力的石斛保健品及其制备方法和应用。
背景技术
免疫力是人体自身的防御机制，是人体识别和消灭外来侵入的任何异物(病毒、细菌等)，处理衰老、损伤、死亡、变性的自身细胞以及识别和处理体内突变细胞和病毒感染细胞的能力。现代免疫学认为，免疫力是人体识别和排除“异己”的生理反应。人体内执行这一功能的是免疫***。迄今为止，人们正在寻找一种制作简单、服用方便的提高免疫力的中药保健品。
发明内容
发明目的：为了解决上述问题，本发明的目的在于提供一种提高免疫力的石斛保健品及其制备方法和应用。
技术方案：本发明的目的是通过如下的方案实现的：
一种具有提高免疫力功效的石斛保健品，它所含的活性成分由下列重量份原料配比制备而成：石斛20份、红天葵18份、定心散20份、黄荆根15份、环草20份、小槐花20份、甘草6份。
所述具有提高免疫力的石斛保健品，制备方法步骤为：取上述药材合并，加水煎煮两次，合并煎液，浓缩至65℃时相对密度为1.10-1.20，加入乙醇，搅拌，使含醇量按体积百分比计算达65-85％，静置，过滤，滤液减压浓缩至65℃时相对密度为1.20-1.30并回收乙醇，将浓缩液喷雾干燥，所得颗粒粉碎成干浸膏粉，加入辅料，制成所需制剂。
所述具有提高免疫力功效的石斛保健品，制备方法中煎煮条件为：第一次加水量为药材重量的8-12倍量，煎煮1-2h，第二次加水量为药材重量的6-10倍量，煎煮1-2h。
所述具有提高免疫力功效的石斛保健品，制备方法中喷雾干燥条件为：进风温度为90-110℃，出风温度为60-90℃，物料温度为60-90℃，雾化压力为0.2-0.5兆帕，喷雾速度为1-10ml/s。
所述具有提高免疫力功效的石斛保健品在制备提高免疫力功效保健品中的应用。
上述中药红天葵，拉丁名为Begoniafimbristipula，为秋海棠科植物紫背天葵的球茎或全株。清热凉血，活血解毒。治暑热高烧，肺热咳嗽，咯血，跌打扭伤，血瘀疼痛，疮毒疥癣，水火烫伤。本发明以全株入药。定心散为莲座蕨科植物定心散莲座蕨的带叶柄基部的根茎。主要用于治神经衰弱，精神***症，热病抽搐等。黄荆根为马鞭草料植物黄荆的根，解表，祛风湿，理气止痛，截疟，驱虫。治感冒，咳喘，风湿，胃痛，痧气腹痛，疟疾。蛲虫病。环草为兰科植物细茎石斛的全草。养阴清热，健脾胃。治热病伤阴，痨伤咳血。小槐花为豆科山蚂蝗属植物小槐花Desmodiumcaudatum(Thunb.)DC.，以根或全株入药。夏、秋采集，洗净晒干，鲜用四季可采。清热解毒，祛风利湿。用于感冒发烧，肠胃炎，痢疾，小儿疳积，风湿关节痛；外用治毒蛇咬伤，痈疖疔疮，乳腺炎。本发明以全株入药。其余为药典品种。
有益效果：免疫力低按中医说法就是正气不足。治疗上不仅要补虚扶正，也应活血化瘀、清热解毒。因此本方中红天葵、定心散补虚扶正、活血化瘀为君药，黄荆根、环草、养阴清热，健脾胃为臣药，小槐花、石斛、甘草清热解毒，祛风利湿为佐使药，诸药相合，共奏益气活血，用于提高免疫力。
具体实施方式
以下通过实施例形式，对本发明的上述内容再作进一步的详细说明，但不应将此理解为本发明上述主题的范围仅限于以下的实例，凡基于本发明上述内容所实现的技术均属于本发明的范围。
实施例1：颗粒剂的制备
取石斛20g、红天葵18g、定心散20g、黄荆根15g、环草20g、小槐花20g、甘草6g药材混合，加水煎煮两次，第一次加水为药材重量的8倍量，煎煮1.5h，第二次加水为药材重量的6倍量，煎煮1h，合并煎液，滤过，滤液浓缩至相对密度1.10(65℃)，加适量乙醇使含醇量(体积分数)达65％，搅拌，静置24小时，滤过，滤液回收乙醇并浓缩至相对密度1.10(65℃)的浸膏，经喷雾干燥(条件为进风温度为100℃，出风温度为80℃，物料温度为70℃，雾化压力为0.2兆帕，喷雾速度为5ml/s。)，粉碎成干浸膏粉，再加入适50g糊精，用适量80％乙醇润湿，制软材，过14目筛制粒，70℃干燥，60目整粒，得颗粒剂。
实施例2：片剂的制备
取石斛20g、红天葵18g、定心散20g、黄荆根15g、环草20g、小槐花20g、甘草6g药材混合，加水煎煮两次，第次加水为药材重量的10倍量，煎煮2h，第二次加水为药材重量的8倍量，煎煮1h，合并煎液，滤过，滤液浓缩至相对密度1.15(65℃)，加适量乙醇使含醇量(体积分数)达75％，搅拌，静置24小时，滤过，滤液回收乙醇并浓缩至相对密度1.25(65℃)的浸膏，经喷雾干燥(条件为进风温度为120℃，出风温度为90℃，物料温度为80℃，雾化压力为0.3兆帕，喷雾速度为7.5/s。)，粉碎成干浸膏粉，再加入淀粉50g，混合均匀，用适量80％乙醇润湿，制软材，过30目筛制粒，于70～80℃干燥，用60目筛整粒，压片，包脂衣，分装，外包装，送检合格，得成品。
实施例3：胶囊剂的制备
取石斛20g、红天葵18g、定心散20g、黄荆根15g、环草20g、小槐花20g、甘草6g药材混合，加水煎煮两次，第一次加水为药材重量的10倍量，煎煮1.5h，第二次加水为药材重量的8倍量，煎煮1.5h，合并煎液，滤过，滤液浓缩至相对密度1.15(65℃)，加适量乙醇使含醇量(体积分数)达75％，搅拌，静置24小时，滤过，滤液回收乙醇并浓缩至相对密度1.25(65℃)的浸膏，经喷雾干燥(条件为进风温度为120℃，出风温度为90℃，物料温度为90℃，雾化压力为0.4兆帕，喷雾速度为7.5/s。)，粉碎成干浸膏粉，过6号筛，再装入1号胶囊即可得成品。
实施例4：本发明提高免疫力的药效学研究
实验目的：用不同浓度的本发明灌胃小鼠30d，比较本发明和正常组小鼠受ConA诱导的脾脏淋巴细胞增殖的差别，来判断本发明是否增强脾脏淋巴细胞增殖。
实验动物：昆明种小鼠，雄性，体重18-22g，上海斯莱克实验动物有限公司提供，生产许可证：SCXK(沪)2007-0005。
实验药物：按上述颗粒剂实施例的制备方法制备。
实验步骤：小鼠，按体重分层随机分组,每组12只。如下表所示，正常组灌胃给水；盐酸左旋咪唑组灌胃盐酸左旋咪唑；复方低、中、高剂量组分别灌胃1，2，4g·kg-1本发明样品，各组连续灌胃给药30d。无菌取脾，按照常规制成单个细胞悬液，调整细胞浓度为5×105个/mL。将脾细胞混悬液加在24孔板中，每孔1mL，每只动物设二个复孔，一孔正常培养(加50uLPRMI1640培养液)；一孔加50uL刀豆蛋白A(ConA)液(终浓度为4.76ug/mL)。置于5％CO2，37℃CO2孵箱中培养48h。实验结束前4h，每孔吸去上清液700uL，再加入700uL不含胎牛血清的PRMI1640培养液，同时每孔加入50uL5mg/mL的MTT液。培养结束后，每孔加1mL酸性异丙醇，小心吹打均匀至紫色的结晶全部溶解。检测前分装到96孔培养板中，每孔作4个复孔，在570nm波长处测定其光密度值。
实验结果：本发明组小鼠脾脏淋巴细胞受ConA诱导后的增殖率转化值显著高于正常组小鼠，如下表所示。
表1本发明对脾淋巴细胞增殖的影响(n＝12)
注：与正常组相比★★P＜0.01，★P＜0.05。
结论：本发明能够增强脾脏淋巴增殖，因此本发明能提高免疫力，可用于制备提高免疫力功效保健品。

Claims (5)

1.一种具有提高免疫力的石斛保健品，其特征在于，它所含的活性成分由下列重量份原料配比制备而成：石斛20份、红天葵18份、定心散20份、黄荆根15份、环草20份、小槐花20份、甘草6份。
2.如权利要求1所述具有提高免疫力的石斛保健品，其特征在于，制备方法步骤为：取上述药材合并，加水煎煮两次，合并煎液，浓缩至65℃时相对密度为1.10-1.20，加入乙醇，搅拌，使含醇量按体积百分比计算达65-85％，静置，过滤，滤液减压浓缩至65℃时相对密度为1.20-1.30并回收乙醇，将浓缩液喷雾干燥，所得颗粒粉碎成干浸膏粉，加入辅料，制成所需制剂。
3.如权利要求2所述具有提高免疫力功效的石斛保健品，其特征在于，制备方法中煎煮条件为：第一次加水量为药材重量的8-12倍量，煎煮1-2h，第二次加水量为药材重量的6-10倍量，煎煮1-2h。
4.如权利要求2所述具有提高免疫力功效的石斛保健品，其特征在于，制备方法中喷雾干燥条件为：进风温度为90-110℃，出风温度为60-90℃，物料温度为60-90℃，雾化压力为0.2-0.5兆帕，喷雾速度为1-10ml/s。
5.如权利要求1所述具有提高免疫力功效的石斛保健品在提高免疫力功效保健品中的应用。
CN201610071003.3A 2016-02-01 2016-02-01 一种具有提高免疫力的石斛保健品及其制备方法和应用 Withdrawn CN105617023A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610071003.3A CN105617023A (zh) 2016-02-01 2016-02-01 一种具有提高免疫力的石斛保健品及其制备方法和应用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610071003.3A CN105617023A (zh) 2016-02-01 2016-02-01 一种具有提高免疫力的石斛保健品及其制备方法和应用

Publications (1)

Publication Number Publication Date
CN105617023A true CN105617023A (zh) 2016-06-01

Family

ID=56032630

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610071003.3A Withdrawn CN105617023A (zh) 2016-02-01 2016-02-01 一种具有提高免疫力的石斛保健品及其制备方法和应用

Country Status (1)

Country Link
CN (1) CN105617023A (zh)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106343104A (zh) * 2016-08-28 2017-01-25 余芳 一种瓜蒌石斛保健粉的制作方法
CN108514111A (zh) * 2018-03-05 2018-09-11 安徽省霍山县福康石斛开发有限公司 一种养血柔肝石斛糕的制备方法
CN117530380A (zh) * 2023-12-13 2024-02-09 大冶康之堂农业发展有限公司 一种具有肠道调节功效的复合饮料及其制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102614372A (zh) * 2012-04-23 2012-08-01 卞毓平 一种抗疲劳的中药组合物及其制备方法和应用

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102614372A (zh) * 2012-04-23 2012-08-01 卞毓平 一种抗疲劳的中药组合物及其制备方法和应用

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李怀良等: "《糖尿病中医治疗与保健》", 31 October 2011, 安徽科学技术出版社 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106343104A (zh) * 2016-08-28 2017-01-25 余芳 一种瓜蒌石斛保健粉的制作方法
CN108514111A (zh) * 2018-03-05 2018-09-11 安徽省霍山县福康石斛开发有限公司 一种养血柔肝石斛糕的制备方法
CN117530380A (zh) * 2023-12-13 2024-02-09 大冶康之堂农业发展有限公司 一种具有肠道调节功效的复合饮料及其制备方法

Similar Documents

Publication Publication Date Title
CN101632827B (zh) 一种治疗银屑病的中药组合物及其制备方法
CN103110846B (zh) 一种用于治疗高脂血症的中药组合物及其制备方法和应用
CN105535033A (zh) 一种从松露中提取松露多糖的方法
CN105617023A (zh) 一种具有提高免疫力的石斛保健品及其制备方法和应用
CN102526578B (zh) 一种治疗感冒的颗粒药剂
CN105748601A (zh) 一种肉苁蓉的提取方法及肉苁蓉保健品
CN105943576A (zh) 一种刺五加的提取方法及刺五加保健品
CN105769943A (zh) 一种从辣木叶中提取辣木黄酮的方法及辣木保健品
CN105753648A (zh) 一种从樟木枝叶提取龙脑的方法
CN103655952A (zh) 一种用于治疗黄水疮的中药糊剂及其制备方法
CN105535032A (zh) 一种松露多糖的提取方法及松露保健品
CN105777496A (zh) 一种从虎杖中提取白藜芦醇的方法及虎杖保健品
CN103494916B (zh) 一种具有降低血糖功效的中药组合物及其制备方法和应用
CN105616468A (zh) 一种刺五加的提取方法及刺五加保健品
CN104857143A (zh) 一种提高缺氧耐受力的药物制剂
CN105769939A (zh) 一种灵芝孢子的破壁方法及灵芝孢子粉保健品
CN103919845A (zh) 一种提高缺氧耐受力的药物组合物及其制备方法和应用
CN103830371B (zh) 一种促进脑部微循环的药物制剂
CN102988451A (zh) 一种无糖型板蓝根颗粒的制备方法
CN105395862B (zh) 一种含牛膝的药物组合物的应用
CN105663394A (zh) 一种提高免疫力的大枣保健品及其制备方法和应用
CN105148078A (zh) 一种用于治疗口腔溃疡的药物制剂
CN106074935A (zh) 一种鼻炎的中成药及其制备工艺
CN105106684A (zh) 一种用于治疗肝阳上亢型高血压的药物制剂
CN105943633A (zh) 一种肉苁蓉保健品及其应用

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication
WW01 Invention patent application withdrawn after publication

Application publication date: 20160601