CN105613522B

CN105613522B - Oxaziclomefone weeding composition

Info

Publication number: CN105613522B
Application number: CN201410598513.7A
Authority: CN
Inventors: 高同军; 王厚文; 宋德明
Original assignee: FMC China Investment Co Ltd
Current assignee: FMC China Investment Co Ltd
Priority date: 2014-10-30
Filing date: 2014-10-30
Publication date: 2020-06-23
Anticipated expiration: 2034-10-30
Also published as: WO2016066087A1; CN105613522A

Abstract

The invention relates to an oxaziclomefone weeding composition, and provides a herbicide composition which comprises a first active ingredient oxaziclomefone and a second active ingredient, wherein the second active ingredient is selected from the group consisting of metamifop, pyraclonil, benzobicyclon, clomazone, sulfentrazone and azimsulfuron.

Description

Oxaziclomefone weeding composition

Technical Field

The present invention relates to the field of herbicides. More particularly, the present invention relates to a synergistic herbicide composition containing oxaziclomefone and another herbicide as active ingredients.

Background

Weeds in rice fields are undesirable because they can compromise rice growth and thus affect rice yield. Many herbicides suitable for weed control in paddy fields have been developed, and many herbicides have been widely used for weed control in paddy fields. However, the weeds in rice fields are various in types and characteristics, and the damage to the growth of rice and the stage of the damage are different. A single herbicide cannot kill a plurality of weeds simultaneously because of limited weed control spectrum, so farmers need to apply different herbicides for multiple times to effectively control the weeds. Therefore, there is still a need to develop a herbicide having a broad spectrum herbicidal effect to achieve effective control of weeds in paddy fields.

Disclosure of Invention

The combination of different herbicides to obtain synergistic effect is desirable, but the synergistic effect is occasionally obtained, which requires a specific selection of the combination of herbicides and requires a lot of time and effort to be confirmed by necessary experimenters. The invention discovers through a great deal of experiments that when the herbicides are used in combination according to the combination listed by the invention, the synergistic effect can be generated, the respective weed control spectrum is expanded, and compared with the herbicides which are used singly, the weeds can be effectively killed. Meanwhile, the herbicide composition can also obviously reduce the damage of the herbicide to rice, thereby improving the use safety. Specifically, the present invention provides a herbicide composition comprising a first active ingredient oxaziclomefone and a second active ingredient selected from the group consisting of metamifop, pyraclonil, benzobicyclon, clomazone, sulfentrazone and azimsulfuron.

Detailed Description

Unless otherwise indicated, in the present specification, the term "herbicide" means a molecule or combination of molecules that slows the growth of or kills unwanted vegetation, such as, but not limited to, weeds or weeds, broadleaf plants, grasses, especially barnyard grass, moleplant, crab grass, clover, monochoria vaginalis, amaranthus, edible tulip, cyperus rotundus in paddy fields. The term "herbicidally effective amount" means the amount necessary to produce an observable inhibitory effect on the growth of the undesired plant, including plant necrosis, plant death, growth inhibition, reproduction inhibition, proliferation inhibition, and removal, destruction, or otherwise diminishing the occurrence or activity of the undesired plant.

Oxaziclomefone (Oxaziclomefone) is a systemic conduction type herbicide for paddy fields, is mainly absorbed by roots, stems and leaves of weeds, and leaves of the weeds lose green and stop growing until the weeds are withered after contacting with the herbicide. The main control objects are various weeds such as barnyard grass, chickweed, moleplant seed, cyperus rotundus L and the like; has the characteristics of low usage amount of effective components, long suitable pesticide application period, long lasting period, good safety to rice and the like.

Metamifop (Metamifop) is an aryloxy phenoxy propionate herbicide, sensitive weeds are absorbed by stems and leaves, are transmitted to the whole plant, accumulate in meristems, inhibit plant acetyl coenzyme A carboxylase, and cause the synthesis of fatty acid to be hindered, so that the weeds are killed. The sensitive weeds have symptoms such as leaf chlorosis and the like within a few days after the metamifop is applied, the weeds die within 2 weeks after the metamifop is applied, the lasting period can reach about 40 days, and 1 time of application can ensure that the weeds such as barnyard grass, moleplant, large crabgrass and goosegrass are not damaged in the whole growth period of the rice.

Pyraclonil (Pyraclonil) acts via a mechanism which is an inhibitor of protoporphyrinogen oxidase. Has the characteristics of wide herbicidal spectrum, safety to rice and the like, and can be used for preventing and killing annual gramineous weeds, cyperaceous weeds, broadleaf weeds and certain perennial weeds in rice fields.

Benzobicyclon, also known as Benzobicyclon, is a pyrazole herbicide that acts by a mechanism and in a manner that inhibits the biosynthesis of chlorophyll in weeds. The benzobicylon can be absorbed by roots, stems, buds and leaves and can be quickly conducted, and the benzobicylon is characterized by high activity, strong selectivity and broad spectrum, and is safe to rice under reasonable use method and dosage. The benzobicylon has special effect on sedges, broad-leaved weeds and partial gramineous weeds in paddy fields.

Clomazone (Clomazone), also known as Clomazone, is an organic heterocyclic herbicide which can be absorbed by roots and buds of plants, conducted upwards and diffused to leaf parts through xylem to inhibit synthesis of chlorophyll and carotene of sensitive plants, so that the whole weeds are whitened and die in a short period, and the weed control period is over 40 days. The rice is safe under reasonable use method and dosage.

Sulfentrazone (Sufentrazone) is a triazolinone herbicide, and is a contact-killing type selective herbicide, which is applied after seedling, weeds are absorbed through roots and buds, and under the condition of light, in the chlorophyll biosynthesis process, protoporphyrinogen oxidase is inhibited to cause toxic intermediate accumulation, so that the cell membranes of the weeds are damaged, tissues of the weeds are necrotized after light exposure, and leaves are rapidly dehydrated, dried and killed. The rice is safe under reasonable use method and dosage.

The Azimsulfuron is an acetolactate synthase inhibitor, and particularly has good inhibitory activity on biochemical synthesis of branched-chain amino acids (such as valine, leucine and isoleucine), so that division and growth of weed cells are hindered. The weed is absorbed by the roots and leaves of the weeds and is conducted in plants, and the weeds stop growing after poisoning and die. Because the herbicide can be quickly decomposed into metabolites without herbicidal activity in rice bodies, the metabolites are not easy to metabolize in weeds, thereby exerting good herbicidal activity and being very safe to rice.

Herein, unless otherwise specified, the percentage (%) means a weight percentage.

The present invention relates to a herbicide composition comprising a first active ingredient oxaziclomefone and a second active ingredient selected from the group consisting of metamifop, pyraclonil, benzobicyclon, clomazone, sulfentrazone and azimsulfuron. The second active ingredient may be one or more selected from this group.

Preferably, the weight ratio of the first active ingredient to the second active ingredient in the composition is from 20:1 to 1:20, more preferably from 2:1 to 1: 10. Still more preferably 1:1 to 1: 5.

The herbicide composition can be prepared into any agriculturally acceptable dosage form suitable for application according to the conventional technology in the field, including but not limited to oil suspension, missible oil, wettable powder, water dispersible granules, emulsion in water, suspending agent, microemulsion, microcapsule suspending agent and the like.

In another aspect, the present invention provides a herbicidal composition comprising a herbicidally effective amount of the herbicidal composition of the present invention and an agriculturally pharmaceutically acceptable adjuvant. Preferably, the content of the herbicide composition is 0.1-85% by weight of the total weight of the herbicide composition. More preferably 1 to 50% and 5 to 25%. Even more preferably 5%, 10%, 15%, 20% and 25%.

The agriculturally pharmaceutically acceptable auxiliary agents include, for example, solvents, emulsifiers, wetting agents, disintegrants, stabilizers, dispersants, thickeners, penetration enhancers, pH adjusters, antifoaming agents, antifreezes, carriers, safeners, and the like known to be useful for stabilizing the active ingredients in the formulation and exerting the medicinal effect. These adjuvants are all conventional ingredients in the field of pesticide formulations, and the selection of specific ingredients and the determination of the amounts to be used are within the knowledge of those skilled in the art. Some of these adjuvants include, but are not limited to, the following ingredients:

(1) crop oil concentrate (mineral oil (85%) + emulsifier (15%)); benzyl coconut alkyl dimethyl quaternary ammonium salt; a blend of petroleum hydrocarbon, alkyl ester, organic acid, and anionic surfactant; C9-C11 alkyl polyglycoside; a phosphorylated alcohol ethoxylate; natural primary alcohol (C12-C16) ethoxylates; di-sec-butylphenol EO-PO block copolymers; a polysiloxane-methyl end-cap; an emulsified methylated seed oil; tridecyl alcohol (synthetic) ethoxylate (8 EO); tallow amine ethoxylate (15EO) and PEG (400) dioleate-99;

(2) liquid carriers that may be employed include water and organic solvents, commonly used organic solvents include, but are not limited to, petroleum fractions or hydrocarbons such as: mineral oils, aromatic solvents, paraffin oils, and the like; vegetable oils such as soybean oil, vine seed oil, olive oil, castor oil, sunflower seed oil, coconut oil, corn oil, cottonseed oil, linseed oil, palm oil, peanut oil, safflower oil, sesame oil, tung oil and the like; and esters of the above vegetable oils; esters of monohydric or dihydric alcohols, trihydric or other lower polyhydric alcohols (containing 4 to 6 hydroxyl groups), such as 2-ethylhexyl stearate, n-butyl oleate, isopropyl myristate, propylene glycol dioleate, dioctyl succinate, dibutyl adipate, dioctyl phthalate, etc.; esters of mono-, di-, and polycarboxylic acids, and the like. Specific organic solvents include toluene, xylene, naphtha, crop oil (crop oil), acetone, methyl ethyl ketone, cyclohexanone, trichloroethylene, perchloroethylene, ethyl acetate, amyl acetate, butyl acetate, propylene glycol monomethyl ether and diethylene glycol monomethyl ether, methyl alcohol, ethyl alcohol, isopropyl alcohol, amyl alcohol, ethylene glycol, propylene glycol, glycerol, N-methyl-2-pyrrolidone, N-dimethyl alkylamides, dimethyl sulfoxide, liquid fertilizers and the like. In some embodiments, water is the carrier used to dilute the concentrate.

(3) Suitable solid supports include, but are not limited to: talc, pyrophyllite (pyrophyllite clay), silica, activated clay (attapulgus clay), kaolin, diatomaceous earth (kieselguhr), chalk (chalk), diatomaceous earth (diatomaceous earth), lime, calcium carbonate, bentonite, Fuller's earth, cotton seed hulls (cottonsed hull), wheat flour, soy flour, pumice (pumice), wood flour, walnut shell flour (walnut shell flours), lignin, and the like.

(4) In certain embodiments, one or more surfactants are incorporated into the compositions described herein. Such surfactants are advantageously used in solid and liquid compositions, especially compositions designed to be diluted with a carrier prior to application. Surfactants can be anionic, cationic or nonionic in nature and can be used as emulsifying agents, wetting agents, suspending agents, or for other purposes.

(5) Typical surfactants include salts of alkyl sulfates such as diethanolammonium lauryl sulfate; alkyl aryl sulfonates such as calcium dodecylbenzenesulfonate; alkylphenol-alkylene oxide addition products, such as nonylphenol-C18 ethoxylate; alcohol-alkylene oxide addition products, such as tridecyl alcohol-C16 ethoxylate; soaps, such as sodium stearate; alkyl naphthalene sulfonates such as sodium dibutylnaphthalene-sulfonate; dialkyl esters of sulfosuccinates, such as sodium bis (2-ethylhexyl) sulfosuccinate; sorbitol esters, such as sorbitol oleate; quaternary amines, such as lauryl trimethyl ammonium chloride; polyethylene glycol esters of fatty acids, such as polyethylene glycol stearate; block copolymers of ethylene oxide and propylene oxide; and salts of monoalkyl phosphates and salts of dialkyl phosphates; vegetable or seed oils such as soybean oil, rapeseed oil/canola oil, olive oil, castor oil, sunflower oil, coconut oil, corn oil, cottonseed oil, linseed oil, palm oil, peanut oil, safflower oil, sesame oil, tung oil and the like; and esters, particularly methyl esters, of the above vegetable oils.

The herbicidal compositions of the present invention are useful for the control and control of undesirable weeds and plants in rice fields, such as the control of weeds in transplanted paddy fields or dry direct seeded paddy fields. The frequency of application and the amount of application of the herbicidal composition of the present invention vary depending on the weather conditions and the growth conditions of weeds, and the skilled person can determine the necessary frequency of application and the effective amount of application to achieve the effect of killing weeds by conventional means.

In another aspect, the present invention also relates to a method for controlling undesired plants in a paddy field, which comprises applying a herbicidally effective amount of the herbicidal composition or herbicidal composition of the present invention. The undesirable plants are, in particular, Echinochloa crusgalli, Euphorbia lathyris, digitaria sanguinalis, Polygonum syringae, Monochoria scandens, Amaranthus caudatus, Sagittaria indica, Cyperus rotundus.

The following examples are intended to further illustrate the invention, but the invention is not limited thereto. In these examples, all percentages (%) refer to weight percentages unless otherwise indicated.

Example 1

A 20% oxaziclomefone-metamifop suspension concentrate was prepared (weight ratio of oxaziclomefone to metamifop is 1: 3). Weighing the components according to the following proportion, pre-crushing the solid components, adding the solid components and other components into a sand mill for grinding, and mixing the mixture after high shear to prepare the 20% oxaziclomefone-metamifop suspending agent.

Example 2

Preparing 25% oxaziclomefone-pyraclonil wettable powder (the weight ratio of oxaziclomefone to pyraclonil is 1: 4). Weighing the components according to the following proportion, coarsely crushing the solid components, sending the crushed solid components and other components into a mixer, uniformly mixing, and performing jet milling to obtain the 25% oxaziclomefone-pyraclonil wettable powder.

Example 3

Preparing 10% oxaziclomefone-benzobicyclon water dispersible granules (the weight ratio of oxaziclomefone to benzobicyclon is 1: 3). The components are weighed according to the following proportion, and then the 10% oxaziclomefone-bicyclosulfulone water dispersible granule is prepared by dry crushing, granulation, drying and screening.

Example 4

6% oxaziclomefone-azimsulfuron wettable powder is prepared (the weight ratio of oxaziclomefone to azimsulfuron is 2: 1). Weighing the components according to the following proportion, coarsely crushing the solid components, sending the crushed solid components and other components into a mixer, uniformly mixing, and performing jet milling to obtain the 6% oxaziclomefone-tetrazolsulfuron wettable powder.

Example 5

6% oxaziclomefone-clomazone oil suspension is prepared (the weight ratio of oxaziclomefone to clomazone is 1: 2). Weighing the components according to the following proportion, uniformly mixing the original medicine, the solvent and the surfactant under high-speed stirring, and then grinding to obtain the 6% oxaziclomefone-clomazone pine oil suspending agent.

Example 6

A 20% oxaziclomefone-sulfentrazone suspension is prepared (wherein the weight ratio of oxaziclomefone to sulfentrazone is 1: 1). Weighing the components according to the following proportion, dispersing the components at a high speed, mixing uniformly, and grinding to obtain the 20% oxaziclomefone-sulfentrazone suspending agent.

Example 7 pharmacodynamic test

And (5) performing a drug effect test. In order to verify the compounding effect of oxaziclomefone, pyraclonil, sulfentrazone, clomazone and the like, a pesticide effect test is carried out in a paddy field. The agents used in the tests included a single dose of an active ingredient such as oxaziclomefone and the oxaziclomefone compositions of examples 1-6. In the test field, the paddy fields with more grassy weeds, broad-leaved weeds and nutgrass flatsedge, such as barnyard grass, are selected. According to different rice cultivation modes and different application times, 4 groups of experiments are carried out, and each group of experiments are repeated for 3 times. The number of weeds was counted 20 days or 30 days after administration, and weed simulation and rice safety evaluation were calculated according to the following methods.

And the weed control effect percent is (weed number in the blank control area-weed number in the treatment area)/weed number in the blank control area × 100 percent.

The fresh weight inhibition ratio (% as the average fresh weight of rice in the blank control area-the average fresh weight of rice in the treatment area)/the average fresh weight of rice in the blank control area is × 100%.

Specific conditions of each test set, including the agents used, the applied doses, the weeds selected as the subject of killing, the number of weeds before and after application, and the results of weed simulation, are shown in tables 1 to 4, respectively. The number of post-application weed plants listed in the table is the sum of the number of weed plants after each application in 3 replicates.

TABLE 1 closed weeding test for transplanted rice (7 days after transplantation in Qingpu district of Shanghai city)

Table 2: transplanting rice closed weeding test (Jiangsu province Jiangyan city, 11 days after transplantation)

Table 3: transplanting rice closed weeding test (Zhejiang Huzhou city, Zhejiang province, 12 days after transplantation)

Table 4: weeding test for dryland direct seeding rice (Anhui province, nest lake city, 11 days after sowing)

From the test results in tables 1-4, it can be seen that compared with the single agents such as oxaziclomefone, pyraclonil, sulfentrazone and clomazone, the oxaziclomefone compound of the present invention has obvious synergistic effect, for example, the simulation of various weeds selected in the test can reach or exceed 90%, even reach 100%. In addition, the oxaziclomefone mixture also overcomes the problem of narrow weed control spectrum of corresponding single agents, the oxaziclomefone mixture combined according to the mode of the invention greatly expands the weed control spectrum, and various weeds commonly seen in rice fields, such as barnyard grass, eclipta prostrata, monochoria vaginalis, amaranthus marsupium and cyperus rotundus, can be effectively killed by one-time application. Therefore, the oxaziclomefone mixture is more convenient and economical to use and is more environment-friendly.

In addition, compared with a single dose, the oxaziclomefone mixture provided by the invention can reduce the dosage of the herbicide, which is beneficial to reducing the damage of the herbicide to rice (see data on rice safety evaluation in table 1), and improving the safety of the herbicide in rice fields.

Claims

1. A herbicide composition for preventing undesired vegetation in a rice field comprising a first active ingredient oxaziclomefone and a second active ingredient selected from the group consisting of clomazone and sulfentrazone; wherein the ratio of the first active ingredient to the second active ingredient is from 1:1 to 1: 5.

2. The herbicidal composition according to claim 1, the second active ingredient may be one or two.

3. A method for controlling undesired vegetation in a paddy field, which comprises applying a herbicidally effective amount of the herbicide composition as claimed in any one of claims 1 to 2 to a paddy field.

4. The method of claim 3, wherein the paddy field is a transplanted paddy field or a dry direct-seeded paddy field.

5. A herbicidal composition for paddy field comprising a herbicidally effective amount of the herbicidal composition as claimed in any one of claims 1 to 2 and an agriculturally pharmaceutically acceptable adjuvant.

6. The herbicidal composition of claim 5, which is contained in an amount of 0.1 to 85% by weight based on the total weight of the herbicidal composition.