CN105561075A - Chinese herbal medicine electuary for treating psoriasis and preparation method thereof - Google Patents

Abstract

The invention discloses a Chinese herbal medicine electuary for treating psoriasis. The Chinese herbal medicine electuary is prepared from, by weight, 15-20 parts of roots of euphorbia fischeriana, 20-25 parts of chinaroot greenbrier rhizomes, 4-8 parts of euphorbia royleana, 6-10 parts of tea tree roots, 8-15 parts of allium tchongchanense Levl., 6-9 parts of epicarp of juglans regia, 2-4 parts of herb of Chinese buttercup, 16-20 parts of walnut exocarp, 22-25 parts of leaves of excoecaria venenata, 7-11 parts of horsehide, 3-8 parts of hibiscus flowers, 2-6 parts of axillary choerospondias fruit, 4-7 parts of caragana microphylla, 5-9 parts of radix achyranthis bidentatae, 1-6 parts of fraxinus mandshurica, 10-14 parts of herb of intricate clematis and 5-8 parts of anthocephalus chinensis. The Chinese herbal medicine electuary for treating the psoriasis is convenient to eat, lasting, effective, free of side effects, convenient to carry and capable of strengthening the physique.

Description

One treats psoriasic Chinese herbal medicine granule and preparation method thereof

Technical field

The present invention relates to one and treat psoriasic Chinese herbal medicine granule.

Background technology

Psoriasis is a kind of common chronic inflammatory dermatoses being easy to recur with characteristic skin lesion.From the beginning of being inflammatory red papules, about foxtail millet grain is to Semen phaseoli radiati size, and expanding gradually later or merging becomes brownish red speckle, clear border, and have inflammatory blush around, substrate infiltrates obviously, the canescence of surface coverage multilamellar drying or silvery white squama.Scraper surface squama gently, exposes the semitransparent thin film that one deck pale red is shinny gradually, claims film phenomenon.Strike off thin film again, then occur little petechia, claim petechial hemorrhage phenomenon.White squama, shinny thin film and petechial hemorrhage are the psoriatic key characters of diagnosis, are called that three levy.Psoriasis vulgaris is broadly divided into three periods from occurring to finally to disappear: carry out phase, resting stage, catagen.

The psoriasis vulgaris cause of disease is not yet clear, thinks relevant with following factors at present: inherited genetic factors, is the interactional disease of multifactorial inheritance of the many factors such as inherited genetic factors and environmental factors.How immune factor, thought that psoriasis is immunity or inflammation mediated disease in recent years.Infective agent, research confirms that streptococcal infection, infection of staphylococcus aureus, fungal infection are relevant with psoriatic morbidity, and whether viral infection is relevant to onset of psoriasis not yet clear and definite.Endocrine factors, gestation can make skin lesion disappear or alleviate, and skin lesion also can be made to increase the weight of.The impact of the endocrinopathy such as thyroid disease, diabetes on this disease is not obvious.Nervous and Mental Factors, patient can occur that psychoneural changes, and these changes can increase the weight of existing skin lesion.Living habit, medicine factor, environmental factors, research discovery is made moist, infect, drink, take medicine and psychentonia brings out psoriatic Major Risk Factors.May bring out or increase the weight of psoriatic medicine and have β1receptorblocker, NSAID (non-steroidal anti-inflammatory drug), lithium salts, antimalarial, tetracycline, calcium channel blocker, metformin, interferon-ALPHA etc.Environmental factors is relevant with age of onset, and season, weather have impact in psoriatic morbidity and recurrence.

At present for psoriasic external used medicine and innerlich anwenden thing effect general, have larger side effect.

Summary of the invention

The technical problem to be solved in the present invention is to provide a kind of instant, lastingly effectively, has no side effect, easy to carry, the psoriasic Chinese herbal medicine granule for the treatment of simultaneously can strengthened physique.

For solving the problem, the present invention adopts following technical scheme:

One treats psoriasic Chinese herbal medicine granule, is made up of following raw material: euphorbiae fischerianae, Rhizoma Smilacis Chinensis, Euphorbia royleana Boiss., Radix Camelliae sinensis, black colored fragrant-flowered garlic, Semen Juglandis epicarp of Juglans regia L., Herba Ranunculi Chinensis, Exocarpium Juglandis Immaturus, Excoecaria venenata F. N. Wei, Corium Equi, Hibiscus syriacus L., Fructus Choerospondiatis, Herba Caraganae intermediae, Radix Achyranthis Bidentatae, Cortex Fraxini mandshuricae, iron wire Herba speranskiae tuberculatae, group's flower; Described raw material is made up of following parts by weight proportioning: euphorbiae fischerianae 15-20 part, Rhizoma Smilacis Chinensis 20-25 part, Euphorbia royleana Boiss. 4-8 part, Radix Camelliae sinensis 6-10 part, black colored fragrant-flowered garlic 8-15 part, Semen Juglandis epicarp of Juglans regia L. 6-9 part, Herba Ranunculi Chinensis 2-4 part, Exocarpium Juglandis Immaturus 16-20 part, Excoecaria venenata F. N. Wei 22-25 part, Corium Equi 7-11 part, Hibiscus syriacus L. 3-8 part, Fructus Choerospondiatis 2-6 part, Herba Caraganae intermediae 4-7 part, Radix Achyranthis Bidentatae 5-9 part, Cortex Fraxini mandshuricae 1-6 part, iron wire Herba speranskiae tuberculatae 10-14 part, group flower 5-8 part.

Further, the optimum parts by weight proportioning of described raw material consists of: euphorbiae fischerianae 17.5 parts, Rhizoma Smilacis Chinensis 22.5 parts, Euphorbia royleana Boiss. 6 parts, Radix Camelliae sinensis 8 parts, black colored fragrant-flowered garlic 11.5 parts, Semen Juglandis epicarp of Juglans regia L. 7.5 parts, Herba Ranunculi Chinensis 3 parts, Exocarpium Juglandis Immaturus 18 parts, Excoecaria venenata F. N. Wei 23.5 parts, Corium Equi 9 parts, Hibiscus syriacus L. 5.5 parts, Fructus Choerospondiatis 4 parts, Herba Caraganae intermediae 5.5 parts, Radix Achyranthis Bidentatae 7 parts, 3.5 parts, Cortex Fraxini mandshuricae, iron wire Herba speranskiae tuberculatae 12 parts, group spend 6.5 parts.

Further, described euphorbiae fischerianae, through mixing thoroughly with vinegar, is put in pot and is fried to micro-dry, then dry or drying and processing.

Further, described group flower is for plucking summer.

Further, described Corium Equi is kept in shady and cool dry environment.

Further, described Chinese herbal medicine granule makes to take after mixing it with hot water, every day three times, each one bag, one after each meal.

Another technical problem that the present invention will solve is to provide a kind of preparation method for the treatment of psoriasic Chinese herbal medicine granule.

For solving the problems of the technologies described above, the present invention adopts following technical scheme: comprise the following steps:

1) euphorbiae fischerianae, Rhizoma Smilacis Chinensis, Euphorbia royleana Boiss., Radix Camelliae sinensis, black colored fragrant-flowered garlic are put in marmite after cleaning, soak 40-50 minute, first boiling boiling with high heat uses 30-40 minute at a simmer instead, pour out juice, add clear water again, step is the same decocts 45-60 minute, pours out medicinal liquid, the medicinal liquid of twice gained is mixed, for subsequent use;

2) step 1) gained medicinal liquid being put into evaporating dish keeps 90-100 DEG C to evaporate, until obtain medicinal liquid powder, for subsequent use;

3) get Semen Juglandis epicarp of Juglans regia L., Herba Ranunculi Chinensis, Exocarpium Juglandis Immaturus, Excoecaria venenata F. N. Wei, Corium Equi, Hibiscus syriacus L., Fructus Choerospondiatis adopt grind to form 20 order powder for twice, filter out impurity, for subsequent use;

4) by Herba Caraganae intermediae, Radix Achyranthis Bidentatae, Cortex Fraxini mandshuricae, iron wire Herba speranskiae tuberculatae, group's flower mix homogeneously, together put into pot and heat, being heated to smolders changes little fire heating 3-4 minute, flame-out, keeps material temperature to be down to room temperature;

5) use ethanol to extract step 4) gained raw material, obtain Chinese medicine extract, heating obtains powder, for subsequent use;

6) get dextrin and step 2), the drug powder of step 3) and step 5) gained mixs homogeneously, and together heats, then with fashion of extrusion by 20 eye mesh screens, makes uniform granule, for subsequent use;

7) step 6) gained granule is carried out drying, baking temperature is 60 DEG C-80 DEG C, makes granule water content within 2%, for subsequent use;

8) composite aluminium plastic bag is used to pack after step 7) gained dried particles being crossed 0.3-0.5mm mesh screening media.

The invention has the beneficial effects as follows: the euphorbiae fischerianae in the psoriasic Chinese herbal medicine granule of this treatment, Rhizoma Smilacis Chinensis, Euphorbia royleana Boiss. removing mass parasite killing, removing damp to relieve itching has good curative effect for psoriasis, Herba Ranunculi Chinensis, Exocarpium Juglandis Immaturus, Excoecaria venenata F. N. Wei etc. can heighten the effect of a treatment, eliminate the toxic component in medicine, drug administration is had no side effect, and Radix Achyranthis Bidentatae, Cortex Fraxini mandshuricae, iron wire Herba speranskiae tuberculatae etc. can keep lasting medicine.

Detailed description of the invention

Embodiment 1:

Treat a preparation method for psoriasic Chinese herbal medicine granule, comprise the following steps:

1) euphorbiae fischerianae 15 parts, Rhizoma Smilacis Chinensis 20 parts, Euphorbia royleana Boiss. 4 parts, Radix Camelliae sinensis 6 parts, black colored fragrant-flowered garlic 8 parts are put in marmite after cleaning, soak 40-50 minute, first boiling boiling with high heat uses 30-40 minute at a simmer instead, pour out juice, add clear water again, step is the same decocts 45-60 minute, pours out medicinal liquid, the medicinal liquid of twice gained is mixed, for subsequent use;

2) step 1) gained medicinal liquid being put into evaporating dish keeps 90-100 DEG C to evaporate, until obtain medicinal liquid powder, for subsequent use;

3) get Semen Juglandis epicarp of Juglans regia L. 6 parts, Herba Ranunculi Chinensis 2 parts, Exocarpium Juglandis Immaturus 16 parts, Excoecaria venenata F. N. Wei 22 parts, Corium Equi 7 parts, Hibiscus syriacus L. 3 parts, Fructus Choerospondiatis 2 parts adopt grind to form 20 order powder for twice, filter out impurity, for subsequent use;

4) Herba Caraganae intermediae 4 parts, Radix Achyranthis Bidentatae 5 parts, 1 part, Cortex Fraxini mandshuricae, iron wire Herba speranskiae tuberculatae 10 parts, group are spent 5 parts of mix homogeneously, together put into pot and heat, being heated to smolders changes little fire heating 3-4 minute, flame-out, keeps material temperature to be down to room temperature;

5) use ethanol to extract step 4) gained raw material, obtain Chinese medicine extract, heating obtains powder, for subsequent use;

6) get dextrin and step 2), the drug powder of step 3) and step 5) gained mixs homogeneously, and together heats, then with fashion of extrusion by 20 eye mesh screens, makes uniform granule, for subsequent use;

7) step 6) gained granule is carried out drying, baking temperature is 60 DEG C-80 DEG C, makes granule water content within 2%, for subsequent use;

8) composite aluminium plastic bag is used to pack after step 7) gained dried particles being crossed 0.3-0.5mm mesh screening media.

Embodiment 2:

Treat a preparation method for psoriasic Chinese herbal medicine granule, comprise the following steps:

1) euphorbiae fischerianae 17.5 parts, Rhizoma Smilacis Chinensis 22.5 parts, Euphorbia royleana Boiss. 6 parts, Radix Camelliae sinensis 8 parts, black colored fragrant-flowered garlic 11.5 parts are put in marmite after cleaning, soak 40-50 minute, first boiling boiling with high heat uses 30-40 minute at a simmer instead, pour out juice, add clear water again, step is the same decocts 45-60 minute, pours out medicinal liquid, the medicinal liquid of twice gained is mixed, for subsequent use;

2) step 1) gained medicinal liquid being put into evaporating dish keeps 90-100 DEG C to evaporate, until obtain medicinal liquid powder, for subsequent use;

3) get Semen Juglandis epicarp of Juglans regia L. 7.5 parts, Herba Ranunculi Chinensis 3 parts, Exocarpium Juglandis Immaturus 18 parts, Excoecaria venenata F. N. Wei 23.5 parts, Corium Equi 9 parts, Hibiscus syriacus L. 5.5 parts, Fructus Choerospondiatis 4 parts adopt grind to form 20 order powder for twice, filter out impurity, for subsequent use;

4) Herba Caraganae intermediae 5.5 parts, Radix Achyranthis Bidentatae 7 parts, 3.5 parts, Cortex Fraxini mandshuricae, iron wire Herba speranskiae tuberculatae 12 parts, group are spent 6.5 parts of mix homogeneously, together put into pot and heat, being heated to smolders changes little fire heating 3-4 minute, flame-out, keeps material temperature to be down to room temperature;

5) use ethanol to extract step 4) gained raw material, obtain Chinese medicine extract, heating obtains powder, for subsequent use;

6) get dextrin and step 2), the drug powder of step 3) and step 5) gained mixs homogeneously, and together heats, then with fashion of extrusion by 20 eye mesh screens, makes uniform granule, for subsequent use;

7) step 6) gained granule is carried out drying, baking temperature is 60 DEG C-80 DEG C, makes granule water content within 2%, for subsequent use;

8) composite aluminium plastic bag is used to pack after step 7) gained dried particles being crossed 0.3-0.5mm mesh screening media.

Embodiment 3:

Treat a preparation method for psoriasic Chinese herbal medicine granule, comprise the following steps:

1) euphorbiae fischerianae 20 parts, Rhizoma Smilacis Chinensis 25 parts, Euphorbia royleana Boiss. 8 parts, Radix Camelliae sinensis 10 parts, black colored fragrant-flowered garlic 15 parts are put in marmite after cleaning, soak 40-50 minute, first boiling boiling with high heat uses 30-40 minute at a simmer instead, pour out juice, add clear water again, step is the same decocts 45-60 minute, pours out medicinal liquid, the medicinal liquid of twice gained is mixed, for subsequent use;

2) step 1) gained medicinal liquid being put into evaporating dish keeps 90-100 DEG C to evaporate, until obtain medicinal liquid powder, for subsequent use;

3) get Semen Juglandis epicarp of Juglans regia L. 9 parts, Herba Ranunculi Chinensis 4 parts, Exocarpium Juglandis Immaturus 20 parts, Excoecaria venenata F. N. Wei 25 parts, Corium Equi 11 parts, Hibiscus syriacus L. 8 parts, Fructus Choerospondiatis 6 parts adopt grind to form 20 order powder for twice, filter out impurity, for subsequent use;

4) Herba Caraganae intermediae 7 parts, Radix Achyranthis Bidentatae 9 parts, 6 parts, Cortex Fraxini mandshuricae, iron wire Herba speranskiae tuberculatae 14 parts, group are spent 8 parts of mix homogeneously, together put into pot and heat, being heated to smolders changes little fire heating 3-4 minute, flame-out, keeps material temperature to be down to room temperature;

5) use ethanol to extract step 4) gained raw material, obtain Chinese medicine extract, heating obtains powder, for subsequent use;

6) get dextrin and step 2), the drug powder of step 3) and step 5) gained mixs homogeneously, and together heats, then with fashion of extrusion by 20 eye mesh screens, makes uniform granule, for subsequent use;

7) step 6) gained granule is carried out drying, baking temperature is 60 DEG C-80 DEG C, makes granule water content within 2%, for subsequent use;

8) composite aluminium plastic bag is used to pack after step 7) gained dried particles being crossed 0.3-0.5mm mesh screening media.

Experimental example:

Experimental subject: 120 psoriatics, are divided into 3 groups by Therapeutic Method at random: matched group one, matched group two and experimental group, often organizes 40 people.

Test method: matched group one is by external medication, and matched group two is treated by Western medicine for oral administration, and experimental group is treated by medium-height grass electuary of the present invention, and treatment time is 10 days.

Criterion:

Recovery from illness: white squama, shinny thin film and petechial hemorrhage symptom are eliminated.

In recovery from illness: white squama, shinny thin film and petechial hemorrhage symptom are eased.

Do not fully recover: occur white squama, shinny thin film and petechial hemorrhage symptom.

The patient treatment effectiveness comparison of 10 days of 3 groups, the results are shown in following table:

Group	Recovery from illness	In recovery from illness	Do not fully recover
				Matched group one	15	8	17
Matched group two	10	25	5
				Experimental group	30	4	6

By checking 3 groups of experiments, experimental group does not occur treating side effect, and therapeutic effect is good, and matched group one occurs that 10 people have side effect, and matched group two has 5 people's appearance untoward reaction in various degree.

The invention has the beneficial effects as follows: the euphorbiae fischerianae in the psoriasic Chinese herbal medicine granule of this treatment, Rhizoma Smilacis Chinensis, Euphorbia royleana Boiss. removing mass parasite killing, removing damp to relieve itching has good curative effect for psoriasis, Herba Ranunculi Chinensis, Exocarpium Juglandis Immaturus, Excoecaria venenata F. N. Wei etc. can heighten the effect of a treatment, eliminate the toxic component in medicine, drug administration is had no side effect, and Radix Achyranthis Bidentatae, Cortex Fraxini mandshuricae, iron wire Herba speranskiae tuberculatae etc. can keep lasting medicine.

Typical case:

Lee, female, 55 years old, there is psoriasic symptom, do not eradicate disease through long western medicine, cause the untoward reaction of drug side effect on the contrary, health body constitution is caused to decline, skin is from the beginning of being inflammatory red papules, and about foxtail millet grain is to Semen phaseoli radiati size, and expanding gradually later or merging becomes brownish red speckle, clear border, have inflammatory blush around, substrate infiltrates obviously, the canescence of surface coverage multilamellar drying or silvery white squama.Scraper surface squama gently, exposes the semitransparent thin film that one deck pale red is shinny gradually, then strikes off thin film, then there is little petechia, under the guidance of doctor, take the present invention treat psoriasic Chinese herbal medicine granule, after taking 10 days, disease is eradicated, and follows up a case by regular visits to, have no recurrence after half a year.

The above, be only the specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, and any change of expecting without creative work or replacement, all should be encompassed in the new protection domain of this practicality and be as the criterion.

Claims (7)

1. treat a psoriasic Chinese herbal medicine granule, it is characterized in that: be made up of following raw material: euphorbiae fischerianae, Rhizoma Smilacis Chinensis, Euphorbia royleana Boiss., Radix Camelliae sinensis, black colored fragrant-flowered garlic, Semen Juglandis epicarp of Juglans regia L., Herba Ranunculi Chinensis, Exocarpium Juglandis Immaturus, Excoecaria venenata F. N. Wei, Corium Equi, Hibiscus syriacus L., Fructus Choerospondiatis, Herba Caraganae intermediae, Radix Achyranthis Bidentatae, Cortex Fraxini mandshuricae, iron wire Herba speranskiae tuberculatae, group's flower; Described raw material is made up of following parts by weight proportioning: euphorbiae fischerianae 15-20 part, Rhizoma Smilacis Chinensis 20-25 part, Euphorbia royleana Boiss. 4-8 part, Radix Camelliae sinensis 6-10 part, black colored fragrant-flowered garlic 8-15 part, Semen Juglandis epicarp of Juglans regia L. 6-9 part, Herba Ranunculi Chinensis 2-4 part, Exocarpium Juglandis Immaturus 16-20 part, Excoecaria venenata F. N. Wei 22-25 part, Corium Equi 7-11 part, Hibiscus syriacus L. 3-8 part, Fructus Choerospondiatis 2-6 part, Herba Caraganae intermediae 4-7 part, Radix Achyranthis Bidentatae 5-9 part, Cortex Fraxini mandshuricae 1-6 part, iron wire Herba speranskiae tuberculatae 10-14 part, group flower 5-8 part.

2. one as claimed in claim 1 treats psoriasic Chinese herbal medicine granule, it is characterized in that, the optimum parts by weight proportioning of described raw material consists of: euphorbiae fischerianae 17.5 parts, Rhizoma Smilacis Chinensis 22.5 parts, Euphorbia royleana Boiss. 6 parts, Radix Camelliae sinensis 8 parts, black colored fragrant-flowered garlic 11.5 parts, Semen Juglandis epicarp of Juglans regia L. 7.5 parts, Herba Ranunculi Chinensis 3 parts, Exocarpium Juglandis Immaturus 18 parts, Excoecaria venenata F. N. Wei 23.5 parts, Corium Equi 9 parts, Hibiscus syriacus L. 5.5 parts, Fructus Choerospondiatis 4 parts, Herba Caraganae intermediae 5.5 parts, Radix Achyranthis Bidentatae 7 parts, 3.5 parts, Cortex Fraxini mandshuricae, iron wire Herba speranskiae tuberculatae 12 parts, group spend 6.5 parts.

3. one as claimed in claim 2 treats psoriasic Chinese herbal medicine granule, it is characterized in that: described euphorbiae fischerianae, through mixing thoroughly with vinegar, is put in pot and fried to micro-dry, then dry or drying and processing.

4. one as claimed in claim 3 treats psoriasic Chinese herbal medicine granule, it is characterized in that: described group flower is for plucking summer.

5. one as claimed in claim 4 treats psoriasic Chinese herbal medicine granule, it is characterized in that: described Corium Equi is kept in shady and cool dry environment.

6. one as claimed in claim 5 treats psoriasic Chinese herbal medicine granule, it is characterized in that: described Chinese herbal medicine granule makes to take after mixing it with hot water, every day three times, each one bag, one after each meal.

7. a kind of preparation method for the treatment of psoriasic Chinese herbal medicine granule as claimed in claim 1, is characterized in that: comprise the following steps:

1) euphorbiae fischerianae, Rhizoma Smilacis Chinensis, Euphorbia royleana Boiss., Radix Camelliae sinensis, black colored fragrant-flowered garlic are put in marmite after cleaning, soak 40-50 minute, first boiling boiling with high heat uses 30-40 minute at a simmer instead, pour out juice, add clear water again, step is the same decocts 45-60 minute, pours out medicinal liquid, the medicinal liquid of twice gained is mixed, for subsequent use;

2) step 1) gained medicinal liquid being put into evaporating dish keeps 90-100 DEG C to evaporate, until obtain medicinal liquid powder, for subsequent use;

3) get Semen Juglandis epicarp of Juglans regia L., Herba Ranunculi Chinensis, Exocarpium Juglandis Immaturus, Excoecaria venenata F. N. Wei, Corium Equi, Hibiscus syriacus L., Fructus Choerospondiatis adopt grind to form 20 order powder for twice, filter out impurity, for subsequent use;

4) by Herba Caraganae intermediae, Radix Achyranthis Bidentatae, Cortex Fraxini mandshuricae, iron wire Herba speranskiae tuberculatae, group's flower mix homogeneously, together put into pot and heat, being heated to smolders changes little fire heating 3-4 minute, flame-out, keeps material temperature to be down to room temperature;

5) use ethanol to extract step 4) gained raw material, obtain Chinese medicine extract, heating obtains powder, for subsequent use;

6) get dextrin and step 2), the drug powder of step 3) and step 5) gained mixs homogeneously, and together heats, then with fashion of extrusion by 20 eye mesh screens, makes uniform granule, for subsequent use;

7) step 6) gained granule is carried out drying, baking temperature is 60 DEG C-80 DEG C, makes granule water content within 2%, for subsequent use;

8) composite aluminium plastic bag is used to pack after step 7) gained dried particles being crossed 0.3-0.5mm mesh screening media.