CN105535593A - Chinese medical spray for treating periodontitis caused by orthodontic correction and preparation method of Chinese medical spray - Google Patents
Chinese medical spray for treating periodontitis caused by orthodontic correction and preparation method of Chinese medical spray Download PDFInfo
- Publication number
- CN105535593A CN105535593A CN201510995503.1A CN201510995503A CN105535593A CN 105535593 A CN105535593 A CN 105535593A CN 201510995503 A CN201510995503 A CN 201510995503A CN 105535593 A CN105535593 A CN 105535593A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- chinese medical
- spray
- medical spray
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
- A61K36/268—Asarum (wild ginger)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/37—Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/428—Trichosanthes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/634—Forsythia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to the field of traditional Chinese medicine, and particularly relates to Chinese medical spray for treating periodontitis caused by orthodontic correction and a preparation method of the Chinese medical spray. The spray is prepared from the following Chinese medicinal raw materials in parts by weight: 10-15 parts of dried rehmannia root, 15-20 parts of fructus forsythiae, 8-10 parts of cortex moutan, 6-8 parts of Chinese angelica, 6-8 parts of radix et rhizoma rhei, 15-20 parts of coptis root, 10-15 parts of bamboo leaf, 8-10 parts of gypsum, 15-20 parts of mongolian snakegourd root, 6-8 parts of cuttlebone, 10-15 parts of liquorice root, 10-15 parts of radix angelicae pubescentis, 10-15 parts of divaricate saposhnikovia root, 8-10 parts of herba menthae, 10-15 parts of herba taraxaci, 8-10 parts of bush cherry plum root, 4-6 parts of herba asari, 4-6 parts of tengyuch euonymus bark, 15-20 parts of red-rooted salvia root and 6-8 parts of cortex eucommiae. The Chinese medical spray can clear away heat and toxic materials, relieve swelling and pain, remove necrotic tissue, promote granulation and stop bleeding by astringency, can be sprayed at any time, is convenient to carry, effectively maintains periodontal drug concentration, can relieve pain of patients, improves the living quality of the patients, and is more beneficial to treatment of orthodontic correction.
Description
Technical field
The invention belongs to the field of Chinese medicines, particularly a kind for the treatment of is due to orthodontic Chinese medical spray causing periodontitis and preparation method thereof.
Background technology
Periodontitis is the chronic infectious disease involving four kinds of Periodontal Supporting Tissue (gingiva, periodontal membrane, alveolar bone and cementum), often causes the inflammatory destruction of Periodontal Supporting Tissue.Microorganism is the initiation factor causing chronic periodontitis, after orthodontic treatment, because treatments period cleaning of teeth is not thorough, be deposited in inflammation and swelling that bacterial plaque microorganism in the facing of dentogingival junction and gingival sulcus and product thereof cause gingiva, make local microecological environment more be conducive to some Grain-negative Periodontal Pathogens under anaerobic grown to grow, form pathogenic very strong biomembrane, expand by under gingivally on gum, and expand deep periodontal tissue to, every factor that can increase the weight of bacterial plaque and be detained, as tartar, ill fitting prosthesis, food impaction, irregular tooth alignment, anatomic form is abnormal, all can become the local promoting factor of periodontal disease, increase the weight of and accelerate the progress of periodontitis.The responsing reaction of host to microorganism determines that whether periodontitis occurs, and the necessary factor of state of an illness weight, range size, development speed etc.Some systemic disease such as diabetes etc. also have negative effect to periodontitis.In addition, environment and behavial factor, if smoking, stress etc. also may be risk factors.
For the treatment of periodontitis, current doctor trained in Western medicine many employings Perorally administrable antimicrobial anti-inflammation drugs and local periodontal surgery and topical medication etc.If alone anti-inflammation drugs, most drug can only relief of symptoms, is difficult to eradicate, usually can not obtains gratifying effect, and Western medicine to there is price higher, the shortcoming that side effect is larger.Long-term practice through inventor draws, Chinese medicine is controlled periodontitis and had better effect, obtains good effect.
Summary of the invention
According to the deficiencies in the prior art, the invention provides one can heat-clearing and toxic substances removing, reducing swelling and alleviating pain, removing the necrotic tissue and promoting granulation, astringing to arrest bleeding, can spray medicine at any time, easy to carry, drug level in effective maintenance periodontal, thus reach the Chinese medicine formula of significant therapeutic effect and the preparation method of spraying thereof.
A kind for the treatment of disclosed in this invention causes the Chinese medical spray of periodontitis due to orthodontic, formulated by the raw material of Chinese medicine of following parts by weight: Radix Rehmanniae 10-15 part, Fructus Forsythiae 15-20 part, Cortex Moutan 8-10 part, Radix Angelicae Sinensis 6-8 part, Radix Et Rhizoma Rhei 6-8 part, Rhizoma Coptidis 15-20 part, Folium Bambusae 10-15 part, Gypsum Fibrosum 8-10 part, Radix Trichosanthis 15-20 part, Endoconcha Sepiae 6-8 part, Radix Glycyrrhizae 10-15 part, Radix Angelicae Pubescentis 10-15 part, Radix Saposhnikoviae 10-15 part, Herba Menthae 8-10 part, Herba Taraxaci 10-15 part, Radix Pruni Japonicae 8-10 part, Herba Asari 4-6 part, Rhizoma Euonymus 4-6 part, Radix Salviae Miltiorrhizae 15-20 part, Cortex Eucommiae 6-8 part.
Treat because orthodontic causes the Chinese medical spray of periodontitis, preferably formulated by the raw material of Chinese medicine of following parts by weight: Radix Rehmanniae 12 parts, Fructus Forsythiae 17 parts, Cortex Moutan 9 parts, Radix Angelicae Sinensis 7 parts, Radix Et Rhizoma Rhei 7 parts, Rhizoma Coptidis 17 parts, 12 parts, Folium Bambusae, Gypsum Fibrosum 9 parts, Radix Trichosanthis 17 parts, Endoconcha Sepiae 7 parts, 13 parts, Radix Glycyrrhizae, Radix Angelicae Pubescentis 13 parts, Radix Saposhnikoviae 13 parts, Herba Menthae 9 parts, Herba Taraxaci 12 parts, Radix Pruni Japonicae 9 parts, Herba Asari 5 parts, Rhizoma Euonymus 5 parts, Radix Salviae Miltiorrhizae 17 parts, the Cortex Eucommiae 7 parts.
A kind for the treatment of causes the preparation method of the Chinese medical spray of periodontitis due to orthodontic, step is as follows: after being pulverized by proportioning by above-mentioned Chinese medicine, do extraction with the Diluted Alcohol of the 6-8 times amount of medicine gross weight, lixiviating solution is added macromolecule filming material, load to spray in bottle and make spray.
Preferred version is as follows:
Described macromolecule filming material is any one in polyvinyl alcohol, ethylene one acetate ethylene copolymer or cellulose derivative.
Instructions of taking: every two hours spray medicines once.It within 10 days, is a course for the treatment of.
Pharmacology analysis:
Radix Rehmanniae: sweet in the mouth, cold in nature.GUIXIN, liver, kidney channel.Can clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid.For calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis sends out speckle dermexanthesis.
Fructus Forsythiae: bitter in the mouth, cold nature.Return lung, the heart, small intestine meridian.Can heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.
Cortex Moutan: bitter in the mouth, pungent, cold nature.GUIXIN, liver, kidney channel.Can clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.
Radix Angelicae Sinensis: sweet in the mouth, pungent, warm in nature.Return liver, the heart, spleen channel.Can enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Radix Et Rhizoma Rhei: bitter in the mouth, cold in nature.Return spleen, stomach, large intestine, liver, pericardium channel.Can purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury.
Rhizoma Coptidis: bitter in the mouth, cold in nature.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Can heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle.
Folium Bambusae: slightly sweet flavor, cold in nature.GUIXIN, lung, gallbladder, stomach warp.Can clearing heat and relieving fidgetness, diuresis of promoting the production of body fluid.For calentura excessive thirst, pediatric epilepsy scared, cough with dyspnea tells nosebleed, flushed complexion, oliguria also, erosion of the oral mucosa tongue boil.
Gypsum Fibrosum: sweet in the mouth, pungent, property Great Cold.Attach to the lung and stomach meridians.Can clearing away heat-fire, relieving restlessness is quenched the thirst.For fever caused by exogenous pathogenic factors, high hot excessive thirst, dyspnea and cough due to lung-heat, the high Sheng of stomach-fire, headache, toothache.
Radix Trichosanthis: sweet in the mouth, micro-hardship, cold nature.Attach to the lung and stomach meridians.Can clearing away heat and promoting production of body fluid, detumescence and apocenosis.For calentura excessive thirst, lung-heat type cough, interior-heat is quenched one's thirst, sore swollen toxin.
Endoconcha Sepiae: salty in the mouth, puckery, warm in nature.Return spleen, kidney channel.Can astringing to arrest bleeding, relieving leukorrhea by astringents, antacid, sore.For acid regurgitation of having a stomachache, hematemesis and epistaxis, metrorrhagia is had blood in stool, emission and spermatorrhea, leucorrhea with red and white discharge; Peptic Ulcers.
Radix Glycyrrhizae: sweet in the mouth, property is put down.GUIXIN, lung, spleen, stomach warp.Can invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Radix Angelicae Pubescentis: acrid in the mouth, hardship, slightly warm in nature.Return kidney, urinary bladder channel.Can expelling wind and removing dampness, numbness relieving and pain relieving.For anemofrigid-damp arthralgia, lumbocrural pain, few cloudy volt wind headache.
Radix Saposhnikoviae: acrid in the mouth, sweet, warm in nature.Return bladder, liver, spleen channel.Can inducing diaphoresis to dispel wind, victory is wet, relieving convulsion.For headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.
Herba Menthae: acrid in the mouth, cool in nature.Return lung, Liver Channel.Can dispelling wind-heat.Refresh oneself, rash.For anemopyretic cold, pathogenic wind-warm from the beginning of, headache, conjunctival congestion, sore throat, aphtha, rubella, measles, breast the side of body feeling of distension and oppression.
Herba Taraxaci: bitter in the mouth, sweet, cold in nature.Return liver, stomach warp.Can heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.
Radix Pruni Japonicae: bitter in the mouth acid, cool in nature.Return spleen, stomach warp.Can heat clearing away, parasite killing, circulation of qi promoting removing mass.For dental caries pain, fever of children, the stagnation of QI is gathered.
Herba Asari: acrid in the mouth, warm in nature.GUIXIN, lung, kidney channel.Can expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.For anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.
Rhizoma Euonymus: lightly seasoned, property is put down.Return Liver Channel.Can stop blooding, granulation promoting.Cure mainly knife injury.
Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature.GUIXIN, Liver Channel.Can stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
The Cortex Eucommiae: sweet in the mouth, warm in nature.Return liver, kidney channel.Can invigorating the liver and kidney, bone and muscle strengthening, antiabortive.For lumbago due to renal deficiency, muscles and bones is unable, blood leaking in gestation, frequent fetal movement; Hypertension.
Chinese medicine of the present invention can heat-clearing and toxic substances removing, reducing swelling and alleviating pain, removing the necrotic tissue and promoting granulation, astringing to arrest bleeding, can spray medicine at any time, easy to carry, drug level in effective maintenance periodontal, patient's misery can be alleviated, improve the quality of life of patient, be more conducive to the treatment of orthodontic.
Now collection 350 causes the patient of periodontitis due to orthodontic, sprays medicine once every two hours.
Outcome measure:
Cure: inflammatory resolution, gingival swelling and pain disappears, and without inflammatory exudate, periodontal pocket disappears or shoal (<4mm), and frontal resorption is silent oscillation, and tooth mobility II0 turns I0, and masticatory function is improved, and General Symptoms is removed.
Effective: inflammatory resolution, gingival swelling and pain disappears substantially, and substantially without inflammatory exudate, periodontal pocket shoals, and frontal resorption situation is stablized, and tooth mobility alleviates, and masticatory function makes moderate progress, and General Symptoms alleviates;
Invalid: symptom, sign slightly alleviate or the person of not being any change.
It within 10 days, is a course for the treatment of.After using 3 course for the treatment of Chinese medical spray of the present invention, statistical result is as follows:
Case load | Cure number | Cure rate | Significant figure | Invalid number | Total effective rate |
350 | 287 | 82% | 35 | 28 | 92% |
As seen from the above table, after pharmaceutical treatment of the present invention, cure 287 examples, account for 82%, effective 35 examples, account for 10%, and invalid 28 examples, account for 8%, overall efficiency is 92%.As can be seen here, the present invention causes the treatment of periodontitis to have good effect to orthodontic.
Attached several routine case is described further:
Case 1:
Ma, man, 12 years old, carried out orthodontic treatment before three months, owing to not clearing up oral hygiene on time, red swelling of gingiva of now visiting, touches hemorrhage, lower front tooth gingival enlargement, and II degree that touches loosens, and the halitosis of news, large dry stool, red tongue, yellow fur is thick.Use Chinese medical spray of the present invention, treat 1 course for the treatment of, symptom obviously alleviates, and continues 2 courses for the treatment of of use, and recovery from illness is followed up a case by regular visits to after half a year without recurrence.
Case 2:
Grandson, female, 9 years old, had carried out orthodontic treatment before half a year, and existing gingiva is often hemorrhage, stings thing unable, lower front odontoseisis, occasionally has dental bed swelling, suppurates, oral administration " antibiotic medicine " remission afterwards.But can not cure, prolonged and repeated outbreak always.Rear use medicine of the present invention is after 5 days, and dental bed swelling, transference cure of suppurating, gingival hemorrhage phenomenon disappears substantially, and use after 15 days, above-mentioned symptom disappears completely, stings thing strong.Follow up a case by regular visits to after half a year, the state of an illness does not recur.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in detail, but the present invention is not limited to specific embodiment.
Embodiment 1:
Treat because orthodontic causes the Chinese medical spray of periodontitis, formulated by the raw material of Chinese medicine of following parts by weight: Radix Rehmanniae 15 parts, Fructus Forsythiae 15 parts, Cortex Moutan 10 parts, Radix Angelicae Sinensis 6 parts, Radix Et Rhizoma Rhei 8 parts, Rhizoma Coptidis 15 parts, 15 parts, Folium Bambusae, Gypsum Fibrosum 8 parts, Radix Trichosanthis 20 parts, Endoconcha Sepiae 6 parts, 15 parts, Radix Glycyrrhizae, Radix Angelicae Pubescentis 10 parts, Radix Saposhnikoviae 15 parts, Herba Menthae 8 parts, Herba Taraxaci 15 parts, Radix Pruni Japonicae 8 parts, Herba Asari 6 parts, Rhizoma Euonymus 4 parts, Radix Salviae Miltiorrhizae 20 parts, the Cortex Eucommiae 6 parts.
Embodiment 2:
Treat because orthodontic causes the Chinese medical spray of periodontitis, formulated by the raw material of Chinese medicine of following parts by weight: Radix Rehmanniae 10 parts, Fructus Forsythiae 20 parts, Cortex Moutan 8 parts, Radix Angelicae Sinensis 8 parts, Radix Et Rhizoma Rhei 6 parts, Rhizoma Coptidis 20 parts, 10 parts, Folium Bambusae, Gypsum Fibrosum 10 parts, Radix Trichosanthis 15 parts, Endoconcha Sepiae 8 parts, 10 parts, Radix Glycyrrhizae, Radix Angelicae Pubescentis 15 parts, Radix Saposhnikoviae 10 parts, Herba Menthae 10 parts, Herba Taraxaci 10 parts, Radix Pruni Japonicae 10 parts, Herba Asari 4 parts, Rhizoma Euonymus 6 parts, Radix Salviae Miltiorrhizae 15 parts, the Cortex Eucommiae 8 parts.
Embodiment 3:
Treat because orthodontic causes the Chinese medical spray of periodontitis, formulated by the raw material of Chinese medicine of following parts by weight: Radix Rehmanniae 12 parts, Fructus Forsythiae 17 parts, Cortex Moutan 9 parts, Radix Angelicae Sinensis 7 parts, Radix Et Rhizoma Rhei 7 parts, Rhizoma Coptidis 17 parts, 12 parts, Folium Bambusae, Gypsum Fibrosum 9 parts, Radix Trichosanthis 17 parts, Endoconcha Sepiae 7 parts, 13 parts, Radix Glycyrrhizae, Radix Angelicae Pubescentis 13 parts, Radix Saposhnikoviae 13 parts, Herba Menthae 9 parts, Herba Taraxaci 12 parts, Radix Pruni Japonicae 9 parts, Herba Asari 5 parts, Rhizoma Euonymus 5 parts, Radix Salviae Miltiorrhizae 17 parts, the Cortex Eucommiae 7 parts.
Embodiment 4:
A kind for the treatment of causes the preparation method of the Chinese medical spray of periodontitis due to orthodontic, step is as follows: after being pulverized by proportioning by the Chinese medicine in embodiment 1, extraction is done with the Diluted Alcohol of 6 times amount of medicine gross weight, lixiviating solution is added macromolecule filming material, loads to spray in bottle and make spray.Described macromolecule filming material is polyvinyl alcohol.
Instructions of taking: every two hours spray medicines once.It within 10 days, is a course for the treatment of.
Embodiment 5:
A kind for the treatment of causes the preparation method of the Chinese medical spray of periodontitis due to orthodontic, step is as follows: after being pulverized by proportioning by the Chinese medicine in embodiment 2, extraction is done with the Diluted Alcohol of 8 times amount of medicine gross weight, lixiviating solution is added macromolecule filming material, loads to spray in bottle and make spray.Described macromolecule filming material is ethylene one acetate ethylene copolymer.
Instructions of taking: every two hours spray medicines once.It within 10 days, is a course for the treatment of.
Embodiment 6:
A kind for the treatment of causes the preparation method of the Chinese medical spray of periodontitis due to orthodontic, step is as follows: after being pulverized by proportioning by the Chinese medicine in embodiment 3, extraction is done with the Diluted Alcohol of 8 times amount of medicine gross weight, lixiviating solution is added macromolecule filming material, loads to spray in bottle and make spray.Described macromolecule filming material is cellulose derivative.
Instructions of taking: every two hours spray medicines once.It within 10 days, is a course for the treatment of.
Below the present invention be described in detail, the above, be only the preferred embodiment of the present invention, when not limiting the scope of the present invention, namely allly does impartial change according to the application's scope and modify, all should still belong in covering scope of the present invention.
Claims (4)
1. treatment causes the Chinese medical spray of periodontitis due to orthodontic, it is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: Radix Rehmanniae 10-15 part, Fructus Forsythiae 15-20 part, Cortex Moutan 8-10 part, Radix Angelicae Sinensis 6-8 part, Radix Et Rhizoma Rhei 6-8 part, Rhizoma Coptidis 15-20 part, Folium Bambusae 10-15 part, Gypsum Fibrosum 8-10 part, Radix Trichosanthis 15-20 part, Endoconcha Sepiae 6-8 part, Radix Glycyrrhizae 10-15 part, Radix Angelicae Pubescentis 10-15 part, Radix Saposhnikoviae 10-15 part, Herba Menthae 8-10 part, Herba Taraxaci 10-15 part, Radix Pruni Japonicae 8-10 part, Herba Asari 4-6 part, Rhizoma Euonymus 4-6 part, Radix Salviae Miltiorrhizae 15-20 part, Cortex Eucommiae 6-8 part.
2. a kind for the treatment of according to claim 1 causes the Chinese medical spray of periodontitis due to orthodontic, it is characterized in that: formulated by the raw material of Chinese medicine of following parts by weight: Radix Rehmanniae 12 parts, Fructus Forsythiae 17 parts, Cortex Moutan 9 parts, Radix Angelicae Sinensis 7 parts, Radix Et Rhizoma Rhei 7 parts, Rhizoma Coptidis 17 parts, 12 parts, Folium Bambusae, Gypsum Fibrosum 9 parts, Radix Trichosanthis 17 parts, Endoconcha Sepiae 7 parts, 13 parts, Radix Glycyrrhizae, Radix Angelicae Pubescentis 13 parts, Radix Saposhnikoviae 13 parts, Herba Menthae 9 parts, Herba Taraxaci 12 parts, Radix Pruni Japonicae 9 parts, Herba Asari 5 parts, Rhizoma Euonymus 5 parts, Radix Salviae Miltiorrhizae 17 parts, the Cortex Eucommiae 7 parts.
3. a treatment according to claim 1 causes the preparation method of the Chinese medical spray of periodontitis due to orthodontic, it is characterized in that step is as follows: after being pulverized by proportioning by above-mentioned Chinese medicine, extraction is done with the Diluted Alcohol of the 6-8 times amount of medicine gross weight, lixiviating solution is added macromolecule filming material, loads to spray in bottle and make spray.
4. a kind for the treatment of according to claim 3 causes the preparation method of the Chinese medical spray of periodontitis due to orthodontic, it is characterized in that: described macromolecule filming material is any one in polyvinyl alcohol, ethylene one acetate ethylene copolymer or cellulose derivative.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510995503.1A CN105535593A (en) | 2015-12-24 | 2015-12-24 | Chinese medical spray for treating periodontitis caused by orthodontic correction and preparation method of Chinese medical spray |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510995503.1A CN105535593A (en) | 2015-12-24 | 2015-12-24 | Chinese medical spray for treating periodontitis caused by orthodontic correction and preparation method of Chinese medical spray |
Publications (1)
Publication Number | Publication Date |
---|---|
CN105535593A true CN105535593A (en) | 2016-05-04 |
Family
ID=55815489
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510995503.1A Pending CN105535593A (en) | 2015-12-24 | 2015-12-24 | Chinese medical spray for treating periodontitis caused by orthodontic correction and preparation method of Chinese medical spray |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105535593A (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1903329A (en) * | 2005-07-27 | 2007-01-31 | 霍二伟 | Traditional Chinese medicine for treating chronic periodontitis |
CN102091252A (en) * | 2010-12-06 | 2011-06-15 | 济南金鼎信息技术有限公司 | Traditional Chinese medicine composition for treating periodontitis |
CN102423428A (en) * | 2011-12-13 | 2012-04-25 | 赵丹 | Chinese medicine composition for treating periodontitis |
-
2015
- 2015-12-24 CN CN201510995503.1A patent/CN105535593A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1903329A (en) * | 2005-07-27 | 2007-01-31 | 霍二伟 | Traditional Chinese medicine for treating chronic periodontitis |
CN102091252A (en) * | 2010-12-06 | 2011-06-15 | 济南金鼎信息技术有限公司 | Traditional Chinese medicine composition for treating periodontitis |
CN102423428A (en) * | 2011-12-13 | 2012-04-25 | 赵丹 | Chinese medicine composition for treating periodontitis |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102698103B (en) | Chinese medicinal preparation for treating periodontitis | |
CN102641416A (en) | Chinese patent medicine for treating toothache disease | |
CN104940727A (en) | Paste for treating rhinitis and preparation method thereof | |
CN103156984A (en) | Traditional Chinese medicine composition for treating gingivitis and preparation method thereof | |
CN103381266B (en) | Traditional Chinese medicine for treating nervous vomiting | |
CN105106588A (en) | Traditional Chinese medicinal composition for effectively treating constipation | |
CN110393768A (en) | A kind of combined traditional Chinese medicine dabbling drug of Gilt Uterus anti-inflammatory and its preparation method and application | |
CN105412861A (en) | Traditional Chinese medicine composition for treating tubal nowhere and preparation method thereof | |
CN102293981B (en) | Oral drug for treating oral ulcer | |
CN104873862A (en) | Traditional Chinese medicine composition for treating chronic pharyngitis | |
CN105535593A (en) | Chinese medical spray for treating periodontitis caused by orthodontic correction and preparation method of Chinese medical spray | |
CN104815230A (en) | Mouthwash for treating chronic periodontitis | |
CN103520424A (en) | Traditional Chinese medicine preparation for treating periodontitis | |
CN103623196A (en) | Traditional Chinese medicine composition for treating yin-deficiency and fire-excess type periodontitis | |
CN102631554B (en) | Traditional Chinese medicinal composition for treating periodontitis | |
CN102671032B (en) | Traditional Chinese medicine for treating recurrent aphthae | |
CN105687873A (en) | Preparation for treating nasal polyp, and preparation method of preparation | |
CN105031267A (en) | Prescription for treating periodontitis and preparation method | |
CN105496924A (en) | Toothpaste for treating periodontitis | |
CN105687906A (en) | Traditional Chinese medicine preparation for treating periodontal diseases and preparation method | |
CN104940635A (en) | Scald and burn traditional Chinese medicine compound for external use | |
CN105412633A (en) | Traditional Chinese medicinal composition for treating recurrent aphthous ulcer | |
CN105147845A (en) | Traditional Chinese medicine for treating stomach fire toothache | |
CN103656093B (en) | Be used for the treatment of medicine of Sanguis sus domestica dysentery and preparation method thereof | |
CN104887808A (en) | Periodontitis treatment traditional Chinese medicine preparation |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160504 |
|
RJ01 | Rejection of invention patent application after publication |