CN105531289A - 抗cd83抗体及其用途 - Google Patents
抗cd83抗体及其用途 Download PDFInfo
- Publication number
- CN105531289A CN105531289A CN201480011458.5A CN201480011458A CN105531289A CN 105531289 A CN105531289 A CN 105531289A CN 201480011458 A CN201480011458 A CN 201480011458A CN 105531289 A CN105531289 A CN 105531289A
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- CN
- China
- Prior art keywords
- associated proteins
- sequence
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- seqidno
- antibody
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/626—Diabody or triabody
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/72—Increased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Abstract
Description
Claims (28)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361759780P | 2013-02-01 | 2013-02-01 | |
US61/759,780 | 2013-02-01 | ||
PCT/AU2014/000066 WO2014117220A1 (en) | 2013-02-01 | 2014-01-31 | Anti-cd83 antibodies and use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN105531289A true CN105531289A (zh) | 2016-04-27 |
CN105531289B CN105531289B (zh) | 2019-02-22 |
Family
ID=51261317
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201480011458.5A Active CN105531289B (zh) | 2013-02-01 | 2014-01-31 | 抗cd83抗体及其用途 |
Country Status (13)
Country | Link |
---|---|
US (3) | US9840559B2 (zh) |
EP (2) | EP2951208B1 (zh) |
JP (2) | JP6539585B2 (zh) |
KR (2) | KR102204127B1 (zh) |
CN (1) | CN105531289B (zh) |
AU (1) | AU2014213009B2 (zh) |
CA (1) | CA2899960C (zh) |
DK (1) | DK2951208T3 (zh) |
ES (1) | ES2762622T3 (zh) |
MX (1) | MX2015010023A (zh) |
NZ (1) | NZ711543A (zh) |
PT (1) | PT2951208T (zh) |
WO (1) | WO2014117220A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114615992A (zh) * | 2019-08-16 | 2022-06-10 | H.李.莫菲特癌症中心和研究所股份有限公司 | 表达t调节性细胞的抗cd83嵌合抗原受体 |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102204127B1 (ko) | 2013-02-01 | 2021-01-20 | 키라 바이오테크 피티와이 리미티드 | 항-cd83 항체 및 이의 용도 |
NZ731491A (en) * | 2014-10-23 | 2021-12-24 | Kira Biotech Pty Ltd | Cd83 binding proteins and uses thereof |
US20200277396A1 (en) * | 2017-09-13 | 2020-09-03 | Kira Biotech Pty Limited | Treatment Method |
SG11202007755YA (en) * | 2018-02-23 | 2020-09-29 | H Lee Moffitt Cancer Ct & Res | Cd83-binding chimeric antigen receptors |
MX2022000726A (es) | 2019-07-19 | 2022-02-10 | Oncoresponse Inc | Anticuerpos inmunomoduladores y metodos de uso de los mismos. |
Citations (3)
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CN1367688A (zh) * | 1999-04-14 | 2002-09-04 | 美国政府卫生与公众服务部 | 用于诱导对移植物的免疫耐受性的、包含免疫毒素和抑制树突细胞成熟的因子的组合物 |
CN1582165A (zh) * | 2001-11-09 | 2005-02-16 | 辉瑞产品公司 | Cd40的抗体 |
CN101155914A (zh) * | 2005-04-08 | 2008-04-02 | 阿戈斯治疗公司 | 树状细胞组合物和方法 |
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KR102204127B1 (ko) * | 2013-02-01 | 2021-01-20 | 키라 바이오테크 피티와이 리미티드 | 항-cd83 항체 및 이의 용도 |
NZ731491A (en) | 2014-10-23 | 2021-12-24 | Kira Biotech Pty Ltd | Cd83 binding proteins and uses thereof |
US20200277396A1 (en) | 2017-09-13 | 2020-09-03 | Kira Biotech Pty Limited | Treatment Method |
-
2014
- 2014-01-31 KR KR1020157023660A patent/KR102204127B1/ko active IP Right Grant
- 2014-01-31 PT PT147456370T patent/PT2951208T/pt unknown
- 2014-01-31 EP EP14745637.0A patent/EP2951208B1/en active Active
- 2014-01-31 KR KR1020207029681A patent/KR102449868B1/ko active IP Right Grant
- 2014-01-31 CN CN201480011458.5A patent/CN105531289B/zh active Active
- 2014-01-31 JP JP2015555498A patent/JP6539585B2/ja active Active
- 2014-01-31 AU AU2014213009A patent/AU2014213009B2/en active Active
- 2014-01-31 MX MX2015010023A patent/MX2015010023A/es active IP Right Grant
- 2014-01-31 US US14/765,236 patent/US9840559B2/en active Active
- 2014-01-31 ES ES14745637T patent/ES2762622T3/es active Active
- 2014-01-31 EP EP19203675.4A patent/EP3626743A1/en not_active Withdrawn
- 2014-01-31 CA CA2899960A patent/CA2899960C/en active Active
- 2014-01-31 DK DK14745637.0T patent/DK2951208T3/da active
- 2014-01-31 NZ NZ711543A patent/NZ711543A/en not_active IP Right Cessation
- 2014-01-31 WO PCT/AU2014/000066 patent/WO2014117220A1/en active Application Filing
-
2017
- 2017-11-09 US US15/808,423 patent/US10781255B2/en active Active
-
2019
- 2019-01-04 JP JP2019000340A patent/JP2019076102A/ja active Pending
-
2020
- 2020-07-09 US US16/924,860 patent/US11725054B2/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1367688A (zh) * | 1999-04-14 | 2002-09-04 | 美国政府卫生与公众服务部 | 用于诱导对移植物的免疫耐受性的、包含免疫毒素和抑制树突细胞成熟的因子的组合物 |
CN1582165A (zh) * | 2001-11-09 | 2005-02-16 | 辉瑞产品公司 | Cd40的抗体 |
CN101155914A (zh) * | 2005-04-08 | 2008-04-02 | 阿戈斯治疗公司 | 树状细胞组合物和方法 |
Non-Patent Citations (1)
Title |
---|
JOHN WILSON等: "Antibody to the dendritic cell surface activation antigen CD83 prevents acute graft-versus-host disease", 《THE JOURNAL OF EXPERIMENTAL MEDICINE》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114615992A (zh) * | 2019-08-16 | 2022-06-10 | H.李.莫菲特癌症中心和研究所股份有限公司 | 表达t调节性细胞的抗cd83嵌合抗原受体 |
Also Published As
Publication number | Publication date |
---|---|
JP2019076102A (ja) | 2019-05-23 |
US20180201681A1 (en) | 2018-07-19 |
DK2951208T3 (da) | 2020-01-13 |
EP2951208A1 (en) | 2015-12-09 |
EP3626743A1 (en) | 2020-03-25 |
US20150376277A1 (en) | 2015-12-31 |
CN105531289B (zh) | 2019-02-22 |
ES2762622T3 (es) | 2020-05-25 |
NZ711543A (en) | 2020-08-28 |
KR102449868B1 (ko) | 2022-10-04 |
US10781255B2 (en) | 2020-09-22 |
KR102204127B1 (ko) | 2021-01-20 |
KR20200120967A (ko) | 2020-10-22 |
MX2015010023A (es) | 2017-11-17 |
PT2951208T (pt) | 2019-12-30 |
JP2016507521A (ja) | 2016-03-10 |
EP2951208B1 (en) | 2019-11-13 |
CA2899960C (en) | 2022-05-03 |
AU2014213009A1 (en) | 2015-09-17 |
KR20150135250A (ko) | 2015-12-02 |
CA2899960A1 (en) | 2014-08-07 |
AU2014213009B2 (en) | 2019-01-03 |
WO2014117220A1 (en) | 2014-08-07 |
US20200339684A1 (en) | 2020-10-29 |
EP2951208A4 (en) | 2016-10-19 |
US9840559B2 (en) | 2017-12-12 |
JP6539585B2 (ja) | 2019-07-03 |
US11725054B2 (en) | 2023-08-15 |
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